Result of FASTA (omim) for
pF1KB7583
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7583, 221 aa
1>>>pF1KB7583 221 - 221 aa - 221 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4959+/-0.00035; mu= 4.3177+/- 0.022
mean_var=133.7707+/-26.614, 0's: 0 Z-trim(117.2): 23 B-trim: 116 in 1/54
Lambda= 0.110890
statistics sampled from 28992 (29013) to 28992 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.34), width: 16
Scan time: 7.010
The best scores are: opt bits E(85289)
NP_002348 (OMIM: 600021) max dimerization protein ( 221) 1420 238.0 9.6e-63
NP_001189442 (OMIM: 600021) max dimerization prote ( 220) 1402 235.1 7e-62
NP_001189443 (OMIM: 600021) max dimerization prote ( 211) 1008 172.0 6.4e-43
NP_005953 (OMIM: 176807,600020) max-interacting pr ( 228) 672 118.3 1e-26
NP_569157 (OMIM: 176807,600020) max-interacting pr ( 295) 672 118.4 1.3e-26
NP_001008541 (OMIM: 176807,600020) max-interacting ( 182) 619 109.8 3.1e-24
NP_112590 (OMIM: 609450) max dimerization protein ( 206) 527 95.1 9.2e-20
NP_001136407 (OMIM: 609450) max dimerization prote ( 193) 482 87.9 1.3e-17
>>NP_002348 (OMIM: 600021) max dimerization protein 1 is (221 aa)
initn: 1420 init1: 1420 opt: 1420 Z-score: 1247.4 bits: 238.0 E(85289): 9.6e-63
Smith-Waterman score: 1420; 100.0% identity (100.0% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KB7 MAAAVRMNIQMLLEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNNSSSRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAAAVRMNIQMLLEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNNSSSRST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HNEMEKNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HNEMEKNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQID
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 QLQREQRHLKRQLEKLGIERIRMDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLDWSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QLQREQRHLKRQLEKLGIERIRMDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLDWSS
130 140 150 160 170 180
190 200 210 220
pF1KB7 SSVSDSDERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
:::::::::::::::::::::::::::::::::::::::::
NP_002 SSVSDSDERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
190 200 210 220
>>NP_001189442 (OMIM: 600021) max dimerization protein 1 (220 aa)
initn: 1027 init1: 1027 opt: 1402 Z-score: 1231.9 bits: 235.1 E(85289): 7e-62
Smith-Waterman score: 1402; 99.5% identity (99.5% similar) in 221 aa overlap (1-221:1-220)
10 20 30 40 50 60
pF1KB7 MAAAVRMNIQMLLEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNNSSSRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAVRMNIQMLLEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNNSSSRST
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 HNEMEKNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNEMEKNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQID
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 QLQREQRHLKRQLEKLGIERIRMDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLDWSS
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_001 QLQREQRHLKRQLEKLGIERIRMDSIGSTVSSERSDSDRE-IDVDVESTDYLTGDLDWSS
130 140 150 160 170
190 200 210 220
pF1KB7 SSVSDSDERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
:::::::::::::::::::::::::::::::::::::::::
NP_001 SSVSDSDERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
180 190 200 210 220
>>NP_001189443 (OMIM: 600021) max dimerization protein 1 (211 aa)
initn: 1001 init1: 1001 opt: 1008 Z-score: 891.5 bits: 172.0 E(85289): 6.4e-43
Smith-Waterman score: 1324; 95.5% identity (95.5% similar) in 221 aa overlap (1-221:1-211)
10 20 30 40 50 60
pF1KB7 MAAAVRMNIQMLLEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNNSSSRST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAVRMNIQMLLEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNNSSSR--
10 20 30 40 50
70 80 90 100 110 120
pF1KB7 HNEMEKNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQID
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --------RAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQID
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB7 QLQREQRHLKRQLEKLGIERIRMDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLDWSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLQREQRHLKRQLEKLGIERIRMDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLDWSS
120 130 140 150 160 170
190 200 210 220
pF1KB7 SSVSDSDERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
:::::::::::::::::::::::::::::::::::::::::
NP_001 SSVSDSDERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
180 190 200 210
>>NP_005953 (OMIM: 176807,600020) max-interacting protei (228 aa)
initn: 777 init1: 377 opt: 672 Z-score: 600.5 bits: 118.3 E(85289): 1e-26
Smith-Waterman score: 784; 59.1% identity (81.4% similar) in 220 aa overlap (5-207:4-223)
10 20 30 40 50
pF1KB7 MAAAVRM-NIQMLLEAADYLERREREAEHGYASMLPYNNKDR----DALKRRNKSKKNNS
:.: :.: :::::..::::::: :::::: .: . : .: ....:..:
NP_005 MERVKMINVQRLLEAAEFLERRERECEHGYASSFPSMPSPRLQHSKPPRRLSRAQKHSS
10 20 30 40 50
60 70 80 90 100
pF1KB7 SS-------RSTHNEMEKNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKL
.: ::::::.:::::::::::::.:: :.::::. .:::::.::.::: :::::
NP_005 GSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKL
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 EDCDRKAVHQIDQLQREQRHLKRQLEKLG----IERIRMDSIGSTVSSERSDSDREEIDV
:. .::. ::...:.:::: :: .::.: .:::::::::::.::.::::.::::.:
NP_005 EEAERKSQHQLENLEREQRFLKWRLEQLQGPQEMERIRMDSIGSTISSDRSDSEREEIEV
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 DVESTDYLTGDLD-WSSSSVSDSDERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
:::::.. :..: :..:.:: :...:. :.::::::::.:.:
NP_005 DVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSDEGYSSASVKLSFTS
180 190 200 210 220
>>NP_569157 (OMIM: 176807,600020) max-interacting protei (295 aa)
initn: 708 init1: 377 opt: 672 Z-score: 598.8 bits: 118.4 E(85289): 1.3e-26
Smith-Waterman score: 750; 57.5% identity (80.4% similar) in 219 aa overlap (8-207:72-290)
10 20 30
pF1KB7 MAAAVRMNIQMLLEAADYLERREREA---EHGYASML
:.:.:::::.:::. :.: :::::: .
NP_569 PAGAKPRCPFSDIFNTSENSMEKHINTFLQNVQILLEAASYLEQIEKENKKCEHGYASSF
50 60 70 80 90 100
40 50 60 70 80
pF1KB7 PYNNKDR----DALKRRNKSKKNNSSS-------RSTHNEMEKNRRAHLRLCLEKLKGLV
: . : .: ....:..:.: ::::::.:::::::::::::.:: :.
NP_569 PSMPSPRLQHSKPPRRLSRAQKHSSGSSNTSTANRSTHNELEKNRRAHLRLCLERLKVLI
110 120 130 140 150 160
90 100 110 120 130
pF1KB7 PLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQIDQLQREQRHLKRQLEKLG----IE
::::. .:::::.::.::: ::::::. .::. ::...:.:::: :: .::.: .:
NP_569 PLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLEQLQGPQEME
170 180 190 200 210 220
140 150 160 170 180 190
pF1KB7 RIRMDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLD-WSSSSVSDSDERGSMQSLGSD
::::::::::.::.::::.::::.::::::.. :..: :..:.:: :...:. :.:::
NP_569 RIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDHSSLPSIGSD
230 240 250 260 270 280
200 210 220
pF1KB7 EGYSSTSIKRIKLQDSHKACLGL
:::::.:.:
NP_569 EGYSSASVKLSFTS
290
>>NP_001008541 (OMIM: 176807,600020) max-interacting pro (182 aa)
initn: 614 init1: 322 opt: 619 Z-score: 556.1 bits: 109.8 E(85289): 3.1e-24
Smith-Waterman score: 619; 58.9% identity (85.1% similar) in 168 aa overlap (45-207:13-177)
20 30 40 50 60 70
pF1KB7 AADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKNNSSSRSTHNEMEKNRRAHLRL
.: ....:..:.: .: . ::::::::
NP_001 MPSPRLQHSKPPRRLSRAQKHSSGSSNTSTA---NRRAHLRL
10 20 30
80 90 100 110 120 130
pF1KB7 CLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAVHQIDQLQREQRHLKRQLE
:::.:: :.::::. .:::::.::.::: ::::::. .::. ::...:.:::: :: .::
NP_001 CLERLKVLIPLGPDCTRHTTLGLLNKAKAHIKKLEEAERKSQHQLENLEREQRFLKWRLE
40 50 60 70 80 90
140 150 160 170 180
pF1KB7 KLG----IERIRMDSIGSTVSSERSDSDREEIDVDVESTDYLTGDLD-WSSSSVSDSDER
.: .:::::::::::.::.::::.::::.::::::.. :..: :..:.:: :..
NP_001 QLQGPQEMERIRMDSIGSTISSDRSDSEREEIEVDVESTEFSHGEVDNISTTSISDIDDH
100 110 120 130 140 150
190 200 210 220
pF1KB7 GSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
.:. :.::::::::.:.:
NP_001 SSLPSIGSDEGYSSASVKLSFTS
160 170 180
>>NP_112590 (OMIM: 609450) max dimerization protein 3 is (206 aa)
initn: 574 init1: 295 opt: 527 Z-score: 475.8 bits: 95.1 E(85289): 9.2e-20
Smith-Waterman score: 527; 52.0% identity (79.2% similar) in 173 aa overlap (8-168:7-177)
10 20 30 40 50
pF1KB7 MAAAVRMNIQMLLEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKN----NSS
:::.::.::..::::::::::::::. :. .. ..::.: . ..:
NP_112 MEPLASNIQVLLQAAEFLERREREAEHGYASLCPH--RSPGPIHRRKKRPPQAPGAQDS
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 SRSTHNEMEKNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAV
.::.:::.:: :::.:. :::.:: .::: . .:.:::::: .:..::.:::: ...:
NP_112 GRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRAR
60 70 80 90 100 110
120 130 140 150 160
pF1KB7 HQIDQLQREQRHLKRQLEKL-GI------ERIRMDSIGST-VSSERSDSDREEIDVDVES
. ..:. .:. :.::::.: :. ::.: ::. :. .::::::::.::..:::::
NP_112 QLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVES
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 TDYLTGDLDWSSSSVSDSDERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
NP_112 LVFGGEAELLRGFVAGQEHSYSHGGGAWL
180 190 200
>>NP_001136407 (OMIM: 609450) max dimerization protein 3 (193 aa)
initn: 509 init1: 295 opt: 482 Z-score: 437.3 bits: 87.9 E(85289): 1.3e-17
Smith-Waterman score: 482; 50.6% identity (78.0% similar) in 164 aa overlap (8-159:7-168)
10 20 30 40 50
pF1KB7 MAAAVRMNIQMLLEAADYLERREREAEHGYASMLPYNNKDRDALKRRNKSKKN----NSS
:::.::.::..::::::::::::::. :. .. ..::.: . ..:
NP_001 MEPLASNIQVLLQAAEFLERREREAEHGYASLCPH--RSPGPIHRRKKRPPQAPGAQDS
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 SRSTHNEMEKNRRAHLRLCLEKLKGLVPLGPESSRHTTLSLLTKAKLHIKKLEDCDRKAV
.::.:::.:: :::.:. :::.:: .::: . .:.:::::: .:..::.:::: ...:
NP_001 GRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRAR
60 70 80 90 100 110
120 130 140 150 160
pF1KB7 HQIDQLQREQRHLKRQLEKL-GI------ERIRMDSIGST-VSSERSDSDREEIDVDVES
. ..:. .:. :.::::.: :. ::.: ::. :. .::::::::.
NP_001 QLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQVLPNENGGT
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB7 TDYLTGDLDWSSSSVSDSDERGSMQSLGSDEGYSSTSIKRIKLQDSHKACLGL
NP_001 PNHRPTGRGNNISSHH
180 190
221 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 08:50:36 2016 done: Fri Nov 4 08:50:37 2016
Total Scan time: 7.010 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]