Result of FASTA (omim) for
pF1KB7266
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7266, 344 aa
1>>>pF1KB7266 344 - 344 aa - 344 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6912+/-0.000397; mu= 13.8733+/- 0.024
mean_var=80.2834+/-17.254, 0's: 0 Z-trim(113.3): 57 B-trim: 1101 in 2/47
Lambda= 0.143140
statistics sampled from 22590 (22645) to 22590 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.652), E-opt: 0.2 (0.266), width: 16
Scan time: 5.500
The best scores are: opt bits E(85289)
NP_062559 (OMIM: 609226) WD repeat domain phosphoi ( 344) 2361 497.4 1.8e-140
XP_005256434 (OMIM: 609226) PREDICTED: WD repeat d ( 310) 1771 375.6 8e-104
XP_016880352 (OMIM: 609226) PREDICTED: WD repeat d ( 226) 1541 328.0 1.2e-89
XP_016880351 (OMIM: 609226) PREDICTED: WD repeat d ( 226) 1541 328.0 1.2e-89
NP_001025067 (OMIM: 300526,300894) WD repeat domai ( 360) 858 187.1 5.1e-47
NP_009006 (OMIM: 300526,300894) WD repeat domain p ( 361) 858 187.1 5.2e-47
NP_001028691 (OMIM: 609225) WD repeat domain phosp ( 425) 438 100.4 7.6e-21
NP_057087 (OMIM: 609225) WD repeat domain phosphoi ( 436) 438 100.4 7.7e-21
NP_060453 (OMIM: 609224) WD repeat domain phosphoi ( 446) 429 98.5 2.9e-20
NP_001028690 (OMIM: 609225) WD repeat domain phosp ( 443) 388 90.1 1e-17
NP_056425 (OMIM: 609225) WD repeat domain phosphoi ( 454) 388 90.1 1e-17
NP_001307701 (OMIM: 609224) WD repeat domain phosp ( 364) 382 88.8 2e-17
NP_001028692 (OMIM: 609225) WD repeat domain phosp ( 384) 377 87.8 4.3e-17
XP_016880297 (OMIM: 609224) PREDICTED: WD repeat d ( 318) 335 79.0 1.5e-14
XP_016867441 (OMIM: 609225) PREDICTED: WD repeat d ( 299) 318 75.5 1.6e-13
NP_001265228 (OMIM: 609225) WD repeat domain phosp ( 310) 318 75.5 1.7e-13
XP_006715748 (OMIM: 609225) PREDICTED: WD repeat d ( 310) 318 75.5 1.7e-13
NP_001290177 (OMIM: 609540) WD repeat-containing p ( 212) 145 39.7 0.007
XP_016878126 (OMIM: 609540) PREDICTED: WD repeat-c ( 270) 146 40.0 0.0074
>>NP_062559 (OMIM: 609226) WD repeat domain phosphoinosi (344 aa)
initn: 2361 init1: 2361 opt: 2361 Z-score: 2642.8 bits: 497.4 E(85289): 1.8e-140
Smith-Waterman score: 2361; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344)
10 20 30 40 50 60
pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEML
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 FRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 FRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_062 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA
250 260 270 280 290 300
310 320 330 340
pF1KB7 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL
::::::::::::::::::::::::::::::::::::::::::::
NP_062 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL
310 320 330 340
>>XP_005256434 (OMIM: 609226) PREDICTED: WD repeat domai (310 aa)
initn: 1771 init1: 1771 opt: 1771 Z-score: 1985.0 bits: 375.6 E(85289): 8e-104
Smith-Waterman score: 2040; 90.1% identity (90.1% similar) in 344 aa overlap (1-344:1-310)
10 20 30 40 50 60
pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGGVGHVEML
:::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQ-------------
10 20 30 40
70 80 90 100 110 120
pF1KB7 FRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI
:::::::::::::::::::::::::::::::::::::::
XP_005 ---------------------VMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMI
50 60 70 80
130 140 150 160 170 180
pF1KB7 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLASTEKPPVD
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB7 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAANIYCINFNQ
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB7 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DASLICVSSDHGTVHIFAAEDPKRNKQSSLASASFLPKYFSSKWSFSKFQVPSGSPCICA
210 220 230 240 250 260
310 320 330 340
pF1KB7 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL
::::::::::::::::::::::::::::::::::::::::::::
XP_005 FGTEPNAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMTDDKL
270 280 290 300 310
>>XP_016880352 (OMIM: 609226) PREDICTED: WD repeat domai (226 aa)
initn: 1541 init1: 1541 opt: 1541 Z-score: 1730.3 bits: 328.0 E(85289): 1.2e-89
Smith-Waterman score: 1541; 100.0% identity (100.0% similar) in 226 aa overlap (119-344:1-226)
90 100 110 120 130 140
pF1KB7 KKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLC
::::::::::::::::::::::::::::::
XP_016 MIKVFTFTHNPHQLHVFETCYNPKGLCVLC
10 20 30
150 160 170 180 190 200
pF1KB7 PNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGT
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB7 LIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQS
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB7 SLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEPNAVIAICADGSYYKFLFNPKGEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEPNAVIAICADGSYYKFLFNPKGEC
160 170 180 190 200 210
330 340
pF1KB7 IRDVYAQFLEMTDDKL
::::::::::::::::
XP_016 IRDVYAQFLEMTDDKL
220
>>XP_016880351 (OMIM: 609226) PREDICTED: WD repeat domai (226 aa)
initn: 1541 init1: 1541 opt: 1541 Z-score: 1730.3 bits: 328.0 E(85289): 1.2e-89
Smith-Waterman score: 1541; 100.0% identity (100.0% similar) in 226 aa overlap (119-344:1-226)
90 100 110 120 130 140
pF1KB7 KKKTVIEIEFSTEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLC
::::::::::::::::::::::::::::::
XP_016 MIKVFTFTHNPHQLHVFETCYNPKGLCVLC
10 20 30
150 160 170 180 190 200
pF1KB7 PNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNSNNSLLAFPGTHTGHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGT
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB7 LIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIRIFDTSSGHLIQELRRGSQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQS
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB7 SLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEPNAVIAICADGSYYKFLFNPKGEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLASASFLPKYFSSKWSFSKFQVPSGSPCICAFGTEPNAVIAICADGSYYKFLFNPKGEC
160 170 180 190 200 210
330 340
pF1KB7 IRDVYAQFLEMTDDKL
::::::::::::::::
XP_016 IRDVYAQFLEMTDDKL
220
>>NP_001025067 (OMIM: 300526,300894) WD repeat domain ph (360 aa)
initn: 731 init1: 359 opt: 858 Z-score: 965.0 bits: 187.1 E(85289): 5.1e-47
Smith-Waterman score: 1101; 47.9% identity (75.5% similar) in 351 aa overlap (12-342:8-357)
10 20 30 40 50
pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLE-GGVGHVEM
:. ::::..:: :.::.: :.::..:: :: . . . :..: :::
NP_001 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEM
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 LFRCNYLALVGGGKKPKYPPNKVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRIV
: : : :::::::..::. .:.:::: :.: :.:. :. : .:..:.:.::
NP_001 LHRSNLLALVGGGSSPKFSEISVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKIV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 VVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLAS
.:: . : :..: ::..: :.: :::::: :::. ...::.::: . : .:::::::
NP_001 IVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLAS
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 TEKP-----PVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGS
: :: : : ::.. ..:..:: :: .:.::.::::::.:::.: . . :::::.
NP_001 T-KPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRGT
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 QAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSKW
. :..:::::..:.:..:.:::.::::::: .: . :..:.:: .. .. .: .:.:
NP_001 DPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQW
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 SFSKFQVPSGSPCICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEMT
:...: ::. : :::::: . :.:::::.::...:..:.: :.: :... .:..
NP_001 SLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDIC
300 310 320 330 340 350
pF1KB7 DDKL
::
NP_001 DDDDF
360
>>NP_009006 (OMIM: 300526,300894) WD repeat domain phosp (361 aa)
initn: 836 init1: 359 opt: 858 Z-score: 965.0 bits: 187.1 E(85289): 5.2e-47
Smith-Waterman score: 1092; 47.7% identity (75.3% similar) in 352 aa overlap (12-342:8-358)
10 20 30 40 50
pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLE-GGVGHVEM
:. ::::..:: :.::.: :.::..:: :: . . . :..: :::
NP_009 MTQQPLRGVTSLRFNQDQSCFCCAMETGVRIYNVEPLMEKGHLDHEQVGSMGLVEM
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 LFRCNYLALVGGGKKPKYPP-NKVMIWDDL------KKKTVIEIEFSTEVKAVKLRRDRI
: : : :::::::..::. . :.:::: :.: :.:. :. : .:..:.:.:
NP_009 LHRSNLLALVGGGSSPKFSEISAVLIWDDAREGKDSKEKLVLEFTFTKPVLSVRMRHDKI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 VVVLDSMIKVFTFTHNPHQLHVFETCYNPKGLCVLCPNSNNSLLAFPGTHTGHVQLVDLA
:.:: . : :..: ::..: :.: :::::: :::. ...::.::: . : .::::::
NP_009 VIVLKNRIYVYSFPDNPRKLFEFDTRDNPKGLCDLCPSLEKQLLVFPGHKCGSLQLVDLA
120 130 140 150 160 170
180 190 200 210 220
pF1KB7 STEKP-----PVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRG
:: :: : : ::.. ..:..:: :: .:.::.::::::.:::.: . . :::::
NP_009 ST-KPGTSSAPFTINAHQSDIACVSLNQPGTVVASASQKGTLIRLFDTQSKEKLVELRRG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB7 SQAANIYCINFNQDASLICVSSDHGTVHIFAAEDPKRNKQSSLASAS----FLPKYFSSK
.. :..:::::..:.:..:.:::.::::::: .: . :..:.:: .. .. .: .:.
NP_009 TDPATLYCINFSHDSSFLCASSDKGTVHIFALKDTRLNRRSALARVGKVGPMIGQYVDSQ
240 250 260 270 280 290
290 300 310 320 330
pF1KB7 WSFSKFQVPSGSPCICAFGTEP----NAVIAICADGSYYKFLFNPKGECIRDVYAQFLEM
::...: ::. : :::::: . :.:::::.::...:..:.: :.: :... .:..
NP_009 WSLASFTVPAESACICAFGRNTSKNVNSVIAICVDGTFHKYVFTPDGNCNREAFDVYLDI
300 310 320 330 340 350
340
pF1KB7 TDDKL
::
NP_009 CDDDDF
360
>>NP_001028691 (OMIM: 609225) WD repeat domain phosphoin (425 aa)
initn: 376 init1: 276 opt: 438 Z-score: 495.2 bits: 100.4 E(85289): 7.6e-21
Smith-Waterman score: 489; 32.3% identity (59.4% similar) in 350 aa overlap (10-328:11-349)
10 20 30 40 50
pF1KB7 MNLLPCNPHGNG-LLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEK-QEFLEG-GVGH
: : ::.:.::::. .: : ..:.. .. . . . :. : . :
NP_001 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 VEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVL
:: :: . .:.:. : :. :. . : . . .:. . :::: :.:..: :
NP_001 VERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCL
70 80 90 100 110
120 130 140 150 160 170
pF1KB7 DSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDL
. . . :: ....:. :: :: :::.: :..: ::.::. : :.::. :
NP_001 EESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 ASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAA
. . . ::::.. :. .:.. .::..::::::::.::.:. :. . :.::: .
NP_001 INLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRC
180 190 200 210 220 230
240 250 260 270
pF1KB7 NIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS------------LASASFLP-
: . :..:. .. .::. ::::: : :.. .::.:.::
NP_001 VSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPS
240 250 260 270 280 290
280 290 300 310 320
pF1KB7 ---KYFSSKWSFSKFQVP-SGSPCICAFGTE---PNAVIAICADGSYYKFLFNPK--GEC
..:.. .:. ..: : ::...: : ... ::: : . ..:. :::
NP_001 QVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA-ADGYLYMYNLDPQEGGEC
300 310 320 330 340
330 340
pF1KB7 IRDVYAQFLEMTDDKL
NP_001 ALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYTDDLGAVGGACLEDEASAL
350 360 370 380 390 400
>>NP_057087 (OMIM: 609225) WD repeat domain phosphoinosi (436 aa)
initn: 376 init1: 276 opt: 438 Z-score: 495.1 bits: 100.4 E(85289): 7.7e-21
Smith-Waterman score: 489; 32.3% identity (59.4% similar) in 350 aa overlap (10-328:11-349)
10 20 30 40 50
pF1KB7 MNLLPCNPHGNG-LLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEK-QEFLEG-GVGH
: : ::.:.::::. .: : ..:.. .. . . . :. : . :
NP_057 MNLASQSGEAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 VEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDRIVVVL
:: :: . .:.:. : :. :. . : . . .:. . :::: :.:..: :
NP_057 VERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCL
70 80 90 100 110
120 130 140 150 160 170
pF1KB7 DSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNSLLAFPGTHT-GHVQLVDL
. . . :: ....:. :: :: :::.: :..: ::.::. : :.::. :
NP_057 EESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDT
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 ASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRRGSQAA
. . . ::::.. :. .:.. .::..::::::::.::.:. :. . :.::: .
NP_057 INLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRC
180 190 200 210 220 230
240 250 260 270
pF1KB7 NIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS------------LASASFLP-
: . :..:. .. .::. ::::: : :.. .::.:.::
NP_057 VSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPS
240 250 260 270 280 290
280 290 300 310 320
pF1KB7 ---KYFSSKWSFSKFQVP-SGSPCICAFGTE---PNAVIAICADGSYYKFLFNPK--GEC
..:.. .:. ..: : ::...: : ... ::: : . ..:. :::
NP_057 QVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA-ADGYLYMYNLDPQEGGEC
300 310 320 330 340
330 340
pF1KB7 IRDVYAQFLEMTDDKL
NP_057 ALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVG
350 360 370 380 390 400
>>NP_060453 (OMIM: 609224) WD repeat domain phosphoinosi (446 aa)
initn: 279 init1: 250 opt: 429 Z-score: 484.9 bits: 98.5 E(85289): 2.9e-20
Smith-Waterman score: 451; 29.9% identity (61.4% similar) in 345 aa overlap (18-329:22-352)
10 20 30 40 50
pF1KB7 MNLLPCNPHGNGLLYAGFNQDHGCFACGMENGFRVYNTDPLKEKEKQEFLEGG---
:::: .: : . :..... :. :. . ..:.
NP_060 MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFS---LSSVEQLDQVHGSNEI
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 --VGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEFSTEVKAVKLRRDR
: :: :: . ...:. : : .. .. : . . .:... ...: :.:
NP_060 PDVYIVERLFSSSLVVVVSHTK-----PRQMNVYHFKKGTEICNYSYSSNILSIRLNRQR
60 70 80 90 100 110
120 130 140 150 160
pF1KB7 IVVVLDSMIKVFTFTHNPHQLHVFETCY----NPKGLCVLCPNSNNSLLAFPGTHT-GHV
..: :. : . :: .......: :: :::.: : .:: ::.::. : :..
NP_060 LLVCLEESI----YIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEI
120 130 140 150 160
170 180 190 200 210 220
pF1KB7 QLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIFDTSSGHLIQELRR
: : ... : : ::::.:. :..: .:...:.::::::.::.:.. .:. . :.::
NP_060 VLYD-GNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRR
170 180 190 200 210 220
230 240 250 260 270
pF1KB7 G-SQAANIYCINFNQDASLICVSSDHGTVHIFAAED--PKRNKQSS----------LASA
: .. ..: . :..:....:.::. ::::: :. .: .. : .:..
NP_060 GMKRYVTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAAT
230 240 250 260 270 280
280 290 300 310 320
pF1KB7 SFLPKYFSSKW----SFSKFQVP-SGSPCICAFGT---EPNAVIAICADGSYYKFLFNPK
..:: :. .:. .. ::. ::...: : ..: ..: : . ..:.
NP_060 NYLPTQVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVA-SSSGHLYMYNLDPQ
290 300 310 320 330 340
330 340
pF1KB7 --GECIRDVYAQFLEMTDDKL
:::.
NP_060 DGGECVLIKTHSLLGSGTTEENKENDLRPSLPQSYAATVARPSASSASTVPGYSEDGGAL
350 360 370 380 390 400
>>NP_001028690 (OMIM: 609225) WD repeat domain phosphoin (443 aa)
initn: 343 init1: 276 opt: 388 Z-score: 439.2 bits: 90.1 E(85289): 1e-17
Smith-Waterman score: 443; 30.7% identity (56.5% similar) in 368 aa overlap (10-328:11-367)
10 20 30 40
pF1KB7 MNLLPCNPHGNG-LLYAGFNQDHG------------------CFACGMENGFRVYNTDP
: : ::.:.::::. .: : ..:.. .. .
NP_001 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
10 20 30 40 50 60
50 60 70 80 90
pF1KB7 LKEKEK-QEFLEG-GVGHVEMLFRCNYLALVGGGKKPKYPPNKVMIWDDLKKKTVIEIEF
. . :. : . : :: :: . .:.:. : :. :. . : . . .
NP_001 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSL-KAPR----KLKVCHFKKGTEICNYSY
70 80 90 100 110
100 110 120 130 140 150
pF1KB7 STEVKAVKLRRDRIVVVLDSMIKVFTFTHNPHQLHVF----ETCYNPKGLCVLCPNSNNS
:. . :::: :.:..: :. . . :: ....:. :: :: :::.: :..:
NP_001 SNTILAVKLNRQRLIVCLEESL----YIHNIRDMKVLHTIRETPPNPAGLCALSINNDNC
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB7 LLAFPGTHT-GHVQLVDLASTEKPPVDIPAHEGVLSCIALNLQGTRIATASEKGTLIRIF
::.::. : :.::. : . . . ::::.. :. .:.. .::..::::::::.::.:
NP_001 YLAYPGSATIGEVQVFDTINLRAANM-IPAHDSPLAALAFDASGTKLATASEKGTVIRVF
180 190 200 210 220 230
220 230 240 250 260
pF1KB7 DTSSGHLIQELRRGSQAANIYC-INFNQDASLICVSSDHGTVHIFAAEDPKRNKQSS---
. :. . :.::: . : . :..:. .. .::. ::::: : :..
NP_001 SIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTT
240 250 260 270 280 290
270 280 290 300 310
pF1KB7 ---------LASASFLP----KYFSSKWSFSKFQVP-SGSPCICAFGTE---PNAVIAIC
.::.:.:: ..:.. .:. ..: : ::...: : ...
NP_001 WTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGA-
300 310 320 330 340
320 330 340
pF1KB7 ADGSYYKFLFNPK--GECIRDVYAQFLEMTDDKL
::: : . ..:. :::
NP_001 ADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKAYT
350 360 370 380 390 400
344 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 06:28:50 2016 done: Fri Nov 4 06:28:51 2016
Total Scan time: 5.500 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]