Result of FASTA (omim) for
pF1KB7239
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7239, 224 aa
1>>>pF1KB7239 224 - 224 aa - 224 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2379+/-0.00035; mu= 14.5479+/- 0.022
mean_var=69.2505+/-13.342, 0's: 0 Z-trim(114.8): 91 B-trim: 0 in 0/54
Lambda= 0.154121
statistics sampled from 24741 (24834) to 24741 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.291), width: 16
Scan time: 5.300
The best scores are: opt bits E(85289)
NP_000321 (OMIM: 300839,312700) retinoschisin prec ( 224) 1585 361.1 8.4e-100
NP_001297250 (OMIM: 602281) lactadherin isoform e ( 275) 394 96.4 5.2e-20
NP_001297248 (OMIM: 602281) lactadherin isoform d ( 343) 394 96.4 6.2e-20
NP_001297249 (OMIM: 602281) lactadherin isoform c ( 379) 394 96.4 6.7e-20
NP_005919 (OMIM: 602281) lactadherin isoform a pre ( 387) 394 96.4 6.8e-20
XP_016856149 (OMIM: 188055,227400,600880,601367,61 (2087) 387 95.4 7.8e-19
NP_000121 (OMIM: 188055,227400,600880,601367,61230 (2224) 387 95.4 8.3e-19
XP_011510721 (OMIM: 608698) PREDICTED: discoidin, ( 699) 349 86.6 1.1e-16
NP_563615 (OMIM: 608698) discoidin, CUB and LCCL d ( 775) 349 86.6 1.2e-16
NP_063916 (OMIM: 134500,300841,306700) coagulation ( 216) 338 83.8 2.4e-16
NP_001265571 (OMIM: 606018) EGF-like repeat and di ( 470) 333 82.9 9.7e-16
NP_005702 (OMIM: 606018) EGF-like repeat and disco ( 480) 333 82.9 9.9e-16
NP_000123 (OMIM: 134500,300841,306700) coagulation (2351) 338 84.5 1.6e-15
NP_001171628 (OMIM: 609555) probable carboxypeptid ( 660) 311 78.1 3.8e-14
NP_062555 (OMIM: 609555) probable carboxypeptidase ( 734) 311 78.2 4.1e-14
NP_957716 (OMIM: 602070) neuropilin-2 isoform 6 pr ( 555) 303 76.3 1.1e-13
XP_016860677 (OMIM: 602070) PREDICTED: neuropilin- ( 848) 303 76.4 1.6e-13
XP_016860676 (OMIM: 602070) PREDICTED: neuropilin- ( 853) 303 76.4 1.6e-13
XP_016860675 (OMIM: 602070) PREDICTED: neuropilin- ( 901) 303 76.4 1.7e-13
NP_957719 (OMIM: 602070) neuropilin-2 isoform 5 pr ( 901) 303 76.4 1.7e-13
NP_061004 (OMIM: 602070) neuropilin-2 isoform 4 pr ( 906) 303 76.5 1.7e-13
NP_958436 (OMIM: 602070) neuropilin-2 isoform 3 pr ( 909) 303 76.5 1.7e-13
XP_016860674 (OMIM: 602070) PREDICTED: neuropilin- ( 926) 303 76.5 1.7e-13
NP_003863 (OMIM: 602070) neuropilin-2 isoform 2 pr ( 926) 303 76.5 1.7e-13
XP_005246990 (OMIM: 602070) PREDICTED: neuropilin- ( 931) 303 76.5 1.7e-13
XP_005246991 (OMIM: 602070) PREDICTED: neuropilin- ( 931) 303 76.5 1.7e-13
NP_957718 (OMIM: 602070) neuropilin-2 isoform 1 pr ( 931) 303 76.5 1.7e-13
XP_016867439 (OMIM: 604569,610042,612100) PREDICTE ( 714) 296 74.8 4.1e-13
NP_054860 (OMIM: 604569,610042,612100) contactin-a (1331) 296 75.0 6.7e-13
XP_016877695 (OMIM: 602281) PREDICTED: lactadherin ( 243) 272 69.2 6.9e-12
XP_011513464 (OMIM: 602981) PREDICTED: adipocyte e (1132) 279 71.2 8.1e-12
NP_001120 (OMIM: 602981) adipocyte enhancer-bindin (1158) 279 71.2 8.3e-12
XP_011507890 (OMIM: 191311,271665) PREDICTED: disc ( 559) 255 65.6 1.9e-10
NP_006173 (OMIM: 191311,271665) discoidin domain-c ( 855) 255 65.8 2.6e-10
XP_006711407 (OMIM: 191311,271665) PREDICTED: disc ( 855) 255 65.8 2.6e-10
XP_011507889 (OMIM: 191311,271665) PREDICTED: disc ( 855) 255 65.8 2.6e-10
NP_001014796 (OMIM: 191311,271665) discoidin domai ( 855) 255 65.8 2.6e-10
XP_011507888 (OMIM: 191311,271665) PREDICTED: disc ( 855) 255 65.8 2.6e-10
NP_001309108 (OMIM: 610518) contactin-associated p (1228) 250 64.8 7.6e-10
NP_620481 (OMIM: 610518) contactin-associated prot (1235) 250 64.8 7.6e-10
NP_001309107 (OMIM: 610518) contactin-associated p (1258) 250 64.8 7.7e-10
NP_001309119 (OMIM: 610518) contactin-associated p (1260) 250 64.8 7.7e-10
NP_001309117 (OMIM: 610518) contactin-associated p (1273) 250 64.8 7.8e-10
XP_011521705 (OMIM: 610518) PREDICTED: contactin-a (1283) 250 64.8 7.8e-10
NP_001309110 (OMIM: 610518) contactin-associated p (1307) 250 64.8 7.9e-10
NP_207837 (OMIM: 610518) contactin-associated prot (1308) 250 64.8 8e-10
NP_387504 (OMIM: 610517) contactin-associated prot (1288) 249 64.5 9.2e-10
NP_003623 (OMIM: 602346,616286) contactin-associat (1384) 243 63.2 2.4e-09
XP_016880727 (OMIM: 602346,616286) PREDICTED: cont (1384) 243 63.2 2.4e-09
XP_016858805 (OMIM: 610519) PREDICTED: contactin-a (1227) 239 62.3 4.1e-09
>>NP_000321 (OMIM: 300839,312700) retinoschisin precurso (224 aa)
initn: 1585 init1: 1585 opt: 1585 Z-score: 1912.7 bits: 361.1 E(85289): 8.4e-100
Smith-Waterman score: 1585; 100.0% identity (100.0% similar) in 224 aa overlap (1-224:1-224)
10 20 30 40 50 60
pF1KB7 MSRKIEGFLLLLLFGYEATLGLSSTEDEGEDPWYQKACKCDCQGGPNALWSAGATSLDCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSRKIEGFLLLLLFGYEATLGLSSTEDEGEDPWYQKACKCDCQGGPNALWSAGATSLDCI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 PECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 PECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 QWLQIDLKEIKVISGILTQGRCDIDEWMTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QWLQIDLKEIKVISGILTQGRCDIDEWMTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNS
130 140 150 160 170 180
190 200 210 220
pF1KB7 DRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIRMELLECVSKCA
::::::::::::::::::::::::::::::::::::::::::::
NP_000 DRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIRMELLECVSKCA
190 200 210 220
>>NP_001297250 (OMIM: 602281) lactadherin isoform e [Hom (275 aa)
initn: 344 init1: 189 opt: 394 Z-score: 480.2 bits: 96.4 E(85289): 5.2e-20
Smith-Waterman score: 394; 39.1% identity (69.9% similar) in 156 aa overlap (68-219:121-275)
40 50 60 70 80 90
pF1KB7 CKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYS-SW
:::.... . ::: :. . : . ::
NP_001 QYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSW
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB7 TANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQGRCDID--EWMTKYSVQ
. . :::..:: ::.. ..::::.:: : ..::.::: .. .....:.:
NP_001 NPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVA
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB7 YRTDERLNWIYYKD-QTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIR
: .: :: :.: .::....: :: : : .::.. ::..:..:..:..:: :::.:
NP_001 YSNDSA-NWTEYQDPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALR
220 230 240 250 260
220
pF1KB7 MELLECVSKCA
.::: :
NP_001 LELLGC
270
>--
initn: 177 init1: 98 opt: 195 Z-score: 241.1 bits: 52.1 E(85289): 1.1e-06
Smith-Waterman score: 195; 27.4% identity (65.8% similar) in 117 aa overlap (111-224:4-119)
90 100 110 120 130 140
pF1KB7 ITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQG
:: . .:.. :.:..: . ..:..:::
NP_001 MVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQG
10 20 30
150 160 170 180 190
pF1KB7 --RCDIDEWMTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRTSTVQNLLRPPIISRF
: :.. ..: : . . .. . .: . ... : :: ..... ::.. :. ...
NP_001 ASRLASHEYLKAFKVAYSLNGH-EFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQY
40 50 60 70 80 90
200 210 220
pF1KB7 IRLIPLGWHVRIAIRMELLEC-VSKCA
.:: : . :. ..:.::: : .. ::
NP_001 VRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNP
100 110 120 130 140 150
>>NP_001297248 (OMIM: 602281) lactadherin isoform d prec (343 aa)
initn: 420 init1: 189 opt: 394 Z-score: 478.9 bits: 96.4 E(85289): 6.2e-20
Smith-Waterman score: 394; 39.1% identity (69.9% similar) in 156 aa overlap (68-219:189-343)
40 50 60 70 80 90
pF1KB7 CKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYS-SW
:::.... . ::: :. . : . ::
NP_001 QYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSW
160 170 180 190 200 210
100 110 120 130 140 150
pF1KB7 TANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQGRCDID--EWMTKYSVQ
. . :::..:: ::.. ..::::.:: : ..::.::: .. .....:.:
NP_001 NPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVA
220 230 240 250 260 270
160 170 180 190 200 210
pF1KB7 YRTDERLNWIYYKD-QTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIR
: .: :: :.: .::....: :: : : .::.. ::..:..:..:..:: :::.:
NP_001 YSNDSA-NWTEYQDPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALR
280 290 300 310 320 330
220
pF1KB7 MELLECVSKCA
.::: :
NP_001 LELLGC
340
>--
initn: 254 init1: 161 opt: 278 Z-score: 339.5 bits: 70.6 E(85289): 3.6e-12
Smith-Waterman score: 278; 29.7% identity (64.6% similar) in 175 aa overlap (54-224:17-187)
30 40 50 60 70 80
pF1KB7 STEDEGEDPWYQKACKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITC
: :: :: .:::.:.:... .::.
NP_001 MPRPRLLAALCGALLCAPSLLVALECV--EPLGLENGNIANSQIAA
10 20 30 40
90 100 110 120 130 140
pF1KB7 SNPE-QYVGWYSSWTANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQG--
:. . ..: . :. . :::: :. :: . .:.. :.:..: . ..:..:::
NP_001 SSVRVTFLG-LQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLLRRMWVTGVVTQGAS
50 60 70 80 90 100
150 160 170 180 190 200
pF1KB7 RCDIDEWMTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRTSTVQNLLRPPIISRFIR
: :.. ..: : . . .. . .: . ... : :: ..... ::.. :. ....:
NP_001 RLASHEYLKAFKVAYSLNGH-EFDFIHDVNKKHKEFVGNWNKNAVHVNLFETPVEAQYVR
110 120 130 140 150 160
210 220
pF1KB7 LIPLGWHVRIAIRMELLEC-VSKCA
: : . :. ..:.::: : .. ::
NP_001 LYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSY
170 180 190 200 210 220
>>NP_001297249 (OMIM: 602281) lactadherin isoform c [Hom (379 aa)
initn: 420 init1: 189 opt: 394 Z-score: 478.2 bits: 96.4 E(85289): 6.7e-20
Smith-Waterman score: 394; 39.1% identity (69.9% similar) in 156 aa overlap (68-219:225-379)
40 50 60 70 80 90
pF1KB7 CKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYS-SW
:::.... . ::: :. . : . ::
NP_001 QYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSW
200 210 220 230 240 250
100 110 120 130 140 150
pF1KB7 TANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQGRCDID--EWMTKYSVQ
. . :::..:: ::.. ..::::.:: : ..::.::: .. .....:.:
NP_001 NPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVA
260 270 280 290 300 310
160 170 180 190 200 210
pF1KB7 YRTDERLNWIYYKD-QTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIR
: .: :: :.: .::....: :: : : .::.. ::..:..:..:..:: :::.:
NP_001 YSNDSA-NWTEYQDPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALR
320 330 340 350 360 370
220
pF1KB7 MELLECVSKCA
.::: :
NP_001 LELLGC
>--
initn: 253 init1: 161 opt: 279 Z-score: 340.0 bits: 70.9 E(85289): 3.4e-12
Smith-Waterman score: 279; 28.9% identity (62.1% similar) in 190 aa overlap (40-224:47-223)
10 20 30 40 50 60
pF1KB7 LLLLFGYEATLGLSSTEDEGEDPWYQKACKCDCQGGPNALWSAGATSLDCIPECPYHKPL
: : : :: : .: .::
NP_001 DICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKG-----YAGN---HCETKCV--EPL
20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GFESGEVTPDQITCSNPE-QYVGWYSSWTANKARLNSQGFGCAWLSKFQDSSQWLQIDLK
:.:.:... .::. :. . ..: . :. . :::: :. :: . .:.. :.:..:
NP_001 GLENGNIANSQIAASSVRVTFLG-LQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 EIKVISGILTQG--RCDIDEWMTKYSVQYRTD-ERLNWIYYKDQTGNNRVFYGNSDRTST
. ..:..::: : :.. ..: : . .....:. : . ... : :: .....
NP_001 RRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIH--DVNKKHKEFVGNWNKNAV
130 140 150 160 170 180
190 200 210 220
pF1KB7 VQNLLRPPIISRFIRLIPLGWHVRIAIRMELLEC-VSKCA
::.. :. ....:: : . :. ..:.::: : .. ::
NP_001 HVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSS
190 200 210 220 230 240
NP_001 YKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFG
250 260 270 280 290 300
>>NP_005919 (OMIM: 602281) lactadherin isoform a preprop (387 aa)
initn: 420 init1: 189 opt: 394 Z-score: 478.1 bits: 96.4 E(85289): 6.8e-20
Smith-Waterman score: 394; 39.1% identity (69.9% similar) in 156 aa overlap (68-219:233-387)
40 50 60 70 80 90
pF1KB7 CKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYS-SW
:::.... . ::: :. . : . ::
NP_005 QYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSSYKTWGLHLFSW
210 220 230 240 250 260
100 110 120 130 140 150
pF1KB7 TANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQGRCDID--EWMTKYSVQ
. . :::..:: ::.. ..::::.:: : ..::.::: .. .....:.:
NP_005 NPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFGSVQFVASYKVA
270 280 290 300 310 320
160 170 180 190 200 210
pF1KB7 YRTDERLNWIYYKD-QTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIR
: .: :: :.: .::....: :: : : .::.. ::..:..:..:..:: :::.:
NP_005 YSNDSA-NWTEYQDPRTGSSKIFPGNWDNHSHKKNLFETPILARYVRILPVAWHNRIALR
330 340 350 360 370 380
220
pF1KB7 MELLECVSKCA
.::: :
NP_005 LELLGC
>--
initn: 253 init1: 161 opt: 279 Z-score: 339.9 bits: 70.9 E(85289): 3.4e-12
Smith-Waterman score: 279; 28.9% identity (62.1% similar) in 190 aa overlap (40-224:55-231)
10 20 30 40 50 60
pF1KB7 LLLLFGYEATLGLSSTEDEGEDPWYQKACKCDCQGGPNALWSAGATSLDCIPECPYHKPL
: : : :: : .: .::
NP_005 DICSKNPCHNGGLCEEISQEVRGDVFPSYTCTCLKG-----YAGN---HCETKCV--EPL
30 40 50 60 70
70 80 90 100 110 120
pF1KB7 GFESGEVTPDQITCSNPE-QYVGWYSSWTANKARLNSQGFGCAWLSKFQDSSQWLQIDLK
:.:.:... .::. :. . ..: . :. . :::: :. :: . .:.. :.:..:
NP_005 GLENGNIANSQIAASSVRVTFLG-LQHWVPELARLNRAGMVNAWTPSSNDDNPWIQVNLL
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB7 EIKVISGILTQG--RCDIDEWMTKYSVQYRTD-ERLNWIYYKDQTGNNRVFYGNSDRTST
. ..:..::: : :.. ..: : . .....:. : . ... : :: .....
NP_005 RRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIH--DVNKKHKEFVGNWNKNAV
140 150 160 170 180 190
190 200 210 220
pF1KB7 VQNLLRPPIISRFIRLIPLGWHVRIAIRMELLEC-VSKCA
::.. :. ....:: : . :. ..:.::: : .. ::
NP_005 HVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNGCANPLGLKNNSIPDKQITASSS
200 210 220 230 240 250
NP_005 YKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGIITQGARNFG
260 270 280 290 300 310
>>XP_016856149 (OMIM: 188055,227400,600880,601367,612309 (2087 aa)
initn: 338 init1: 159 opt: 387 Z-score: 459.1 bits: 95.4 E(85289): 7.8e-19
Smith-Waterman score: 387; 39.1% identity (71.8% similar) in 156 aa overlap (68-219:1932-2084)
40 50 60 70 80 90
pF1KB7 CKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWT
:::.:.:.. ::: :. .. : . :
XP_016 RYIRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSW-WGDYWE
1910 1920 1930 1940 1950 1960
100 110 120 130 140 150
pF1KB7 ANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQGRC---DIDEWMTKYSVQ
.::::.:: :: .: ....:::.::: .:: :..:.::: : . . .. .:...
XP_016 PFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQG-CKSLSSEMYVKSYTIH
1970 1980 1990 2000 2010
160 170 180 190 200 210
pF1KB7 YRTDERLNWIYYKDQTGN-NRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIR
: ... ..: :. ... ...: ::.. . :.:.. :::::::::.:: :. ::.:
XP_016 Y-SEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIALR
2020 2030 2040 2050 2060 2070
220
pF1KB7 MELLECVSKCA
.::. :
XP_016 LELFGCDIY
2080
>--
initn: 204 init1: 119 opt: 289 Z-score: 341.3 bits: 73.6 E(85289): 2.8e-12
Smith-Waterman score: 289; 31.5% identity (60.6% similar) in 165 aa overlap (68-224:1773-1930)
40 50 60 70 80 90
pF1KB7 CKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWT
:.:. .: .. .:: : ...:. :
XP_016 GWWLLNTEVGENQRAGMQTPFLIMDRDCRMPMGLSTGIISDSQIKAS---EFLGY---WE
1750 1760 1770 1780 1790
100 110 120 130 140 150
pF1KB7 ANKARLNSQGFGCAW----LSKFQDSSQWLQIDLKEIKVISGILTQGRCDIDE--WMTKY
::::. : :: :. :. :.:.:... .:.:: ::: . . :..
XP_016 PRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGIQTQGAKHYLKSCYTTEF
1800 1810 1820 1830 1840 1850
160 170 180 190 200 210
pF1KB7 SVQYRTDERLNWIYYKDQTGNNRVFY-GNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRI
: : ... .:: .: .. : ... :::: .. .: . :::..:.::. : . :
XP_016 YVAYSSNQ-INWQIFKGNSTRNVMYFNGNSDASTIKENQFDPPIVARYIRISPTRAYNRP
1860 1870 1880 1890 1900 1910
220
pF1KB7 AIRMELLEC-VSKCA
..:.:: : :. :.
XP_016 TLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSWWGDYWEPFRARLNAQGRVNAW
1920 1930 1940 1950 1960 1970
>>NP_000121 (OMIM: 188055,227400,600880,601367,612309,61 (2224 aa)
initn: 338 init1: 159 opt: 387 Z-score: 458.7 bits: 95.4 E(85289): 8.3e-19
Smith-Waterman score: 387; 39.1% identity (71.8% similar) in 156 aa overlap (68-219:2069-2221)
40 50 60 70 80 90
pF1KB7 CKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWT
:::.:.:.. ::: :. .. : . :
NP_000 RYIRISPTRAYNRPTLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSW-WGDYWE
2040 2050 2060 2070 2080 2090
100 110 120 130 140 150
pF1KB7 ANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQGRC---DIDEWMTKYSVQ
.::::.:: :: .: ....:::.::: .:: :..:.::: : . . .. .:...
NP_000 PFRARLNAQGRVNAWQAKANNNKQWLEIDLLKIKKITAIITQG-CKSLSSEMYVKSYTIH
2100 2110 2120 2130 2140 2150
160 170 180 190 200 210
pF1KB7 YRTDERLNWIYYKDQTGN-NRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIR
: ... ..: :. ... ...: ::.. . :.:.. :::::::::.:: :. ::.:
NP_000 Y-SEQGVEWKPYRLKSSMVDKIFEGNTNTKGHVKNFFNPPIISRFIRVIPKTWNQSIALR
2160 2170 2180 2190 2200 2210
220
pF1KB7 MELLECVSKCA
.::. :
NP_000 LELFGCDIY
2220
>--
initn: 210 init1: 119 opt: 289 Z-score: 340.9 bits: 73.6 E(85289): 3e-12
Smith-Waterman score: 289; 31.5% identity (60.6% similar) in 165 aa overlap (68-224:1910-2067)
40 50 60 70 80 90
pF1KB7 CKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWT
:.:. .: .. .:: : ...:. :
NP_000 GWWLLNTEVGENQRAGMQTPFLIMDRDCRMPMGLSTGIISDSQIKAS---EFLGY---WE
1880 1890 1900 1910 1920 1930
100 110 120 130 140 150
pF1KB7 ANKARLNSQGFGCAW----LSKFQDSSQWLQIDLKEIKVISGILTQGRCDIDE--WMTKY
::::. : :: :. :. :.:.:... .:.:: ::: . . :..
NP_000 PRLARLNNGGSYNAWSVEKLAAEFASKPWIQVDMQKEVIITGIQTQGAKHYLKSCYTTEF
1940 1950 1960 1970 1980 1990
160 170 180 190 200 210
pF1KB7 SVQYRTDERLNWIYYKDQTGNNRVFY-GNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRI
: : ... .:: .: .. : ... :::: .. .: . :::..:.::. : . :
NP_000 YVAYSSNQ-INWQIFKGNSTRNVMYFNGNSDASTIKENQFDPPIVARYIRISPTRAYNRP
2000 2010 2020 2030 2040 2050
220
pF1KB7 AIRMELLEC-VSKCA
..:.:: : :. :.
NP_000 TLRLELQGCEVNGCSTPLGMENGKIENKQITASSFKKSWWGDYWEPFRARLNAQGRVNAW
2060 2070 2080 2090 2100 2110
>>XP_011510721 (OMIM: 608698) PREDICTED: discoidin, CUB (699 aa)
initn: 305 init1: 194 opt: 349 Z-score: 420.3 bits: 86.6 E(85289): 1.1e-16
Smith-Waterman score: 349; 36.6% identity (63.4% similar) in 172 aa overlap (54-219:205-373)
30 40 50 60 70 80
pF1KB7 STEDEGEDPWYQKACKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITC
.::: . . ::.::: .. :::
XP_011 GGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTFKTSGCYGTLGMESGVIADPQITA
180 190 200 210 220 230
90 100 110 120 130 140
pF1KB7 SNPEQYV---GWYSSWTANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQG
:. ... : .:: .::::.. : : . : :::::::.. : :.::.: :
XP_011 SSVLEWTDHTGQENSWKPKKARLKKPG--PPWAAFATDEYQWLQIDLNKEKKITGIITTG
240 250 260 270 280 290
150 160 170 180 190
pF1KB7 RCDIDE--WMTKYSVQYRTDERLNWIYYKDQ-TGNNRVFYGNSDRTSTVQNLLRPPIISR
... ... : . : .:. .: :.. . ....: ::.: . :.: . ::::.:
XP_011 STMVEHNYYVSAYRILY-SDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIAR
300 310 320 330 340 350
200 210 220
pF1KB7 FIRLIPLGWHVRIAIRMELLECVSKCA
:::. : :. .::..:::: :
XP_011 FIRVNPTQWQQKIAMKMELLGCQFIPKGRPPKLTQPPPPRNSNDLKNTTAPPKIAKGRAP
360 370 380 390 400 410
>>NP_563615 (OMIM: 608698) discoidin, CUB and LCCL domai (775 aa)
initn: 305 init1: 194 opt: 349 Z-score: 419.6 bits: 86.6 E(85289): 1.2e-16
Smith-Waterman score: 349; 36.6% identity (63.4% similar) in 172 aa overlap (54-219:281-449)
30 40 50 60 70 80
pF1KB7 STEDEGEDPWYQKACKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITC
.::: . . ::.::: .. :::
NP_563 GGQISVVISKGIPYYESSLANNVTSVVGHLSTSLFTFKTSGCYGTLGMESGVIADPQITA
260 270 280 290 300 310
90 100 110 120 130 140
pF1KB7 SNPEQYV---GWYSSWTANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQG
:. ... : .:: .::::.. : : . : :::::::.. : :.::.: :
NP_563 SSVLEWTDHTGQENSWKPKKARLKKPG--PPWAAFATDEYQWLQIDLNKEKKITGIITTG
320 330 340 350 360
150 160 170 180 190
pF1KB7 RCDIDE--WMTKYSVQYRTDERLNWIYYKDQ-TGNNRVFYGNSDRTSTVQNLLRPPIISR
... ... : . : .:. .: :.. . ....: ::.: . :.: . ::::.:
NP_563 STMVEHNYYVSAYRILY-SDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIAR
370 380 390 400 410 420
200 210 220
pF1KB7 FIRLIPLGWHVRIAIRMELLECVSKCA
:::. : :. .::..:::: :
NP_563 FIRVNPTQWQQKIAMKMELLGCQFIPKGRPPKLTQPPPPRNSNDLKNTTAPPKIAKGRAP
430 440 450 460 470 480
>>NP_063916 (OMIM: 134500,300841,306700) coagulation fac (216 aa)
initn: 396 init1: 254 opt: 338 Z-score: 414.5 bits: 83.8 E(85289): 2.4e-16
Smith-Waterman score: 338; 33.3% identity (66.7% similar) in 153 aa overlap (68-219:61-210)
40 50 60 70 80 90
pF1KB7 CKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWT
:::.:: .. ::: :. ... ...:.
NP_063 RYIRLHPTHYSIRSTLRMELMGCDLNSCSMPLGMESKAISDAQITASS--YFTNMFATWS
40 50 60 70 80
100 110 120 130 140 150
pF1KB7 ANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQG-RCDIDEWMTKYSVQYR
.::::. :: . :: . .. ..:::.:... ..:. ::: . . ..: .
NP_063 PSKARLHLQGRSNAWRPQVNNPKEWLQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISS
90 100 110 120 130 140
160 170 180 190 200 210
pF1KB7 TDERLNWIYYKDQTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIRMEL
... .: . :.:. .:: ::.: . : : : ::...:..:. : .: .::.:::.
NP_063 SQDGHQWTLFF-QNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEV
150 160 170 180 190 200
220
pF1KB7 LECVSKCA
: :
NP_063 LGCEAQDLY
210
>--
initn: 166 init1: 156 opt: 163 Z-score: 204.2 bits: 44.9 E(85289): 0.00012
Smith-Waterman score: 163; 42.3% identity (76.9% similar) in 52 aa overlap (174-224:8-59)
150 160 170 180 190 200
pF1KB7 IDEWMTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIP
.::.:: : .. .:.. ::::.:.::: :
NP_063 MRIQDPGKVFFGNVDSSGIKHNIFNPPIIARYIRLHP
10 20 30
210 220
pF1KB7 LGWHVRIAIRMELLEC-VSKCA
. .: ..::::. : ...:.
NP_063 THYSIRSTLRMELMGCDLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQ
40 50 60 70 80 90
224 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 06:13:31 2016 done: Fri Nov 4 06:13:31 2016
Total Scan time: 5.300 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]