Result of FASTA (omim) for
pF1KB7199
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7199, 467 aa
1>>>pF1KB7199 467 - 467 aa - 467 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6699+/-0.000426; mu= 3.5429+/- 0.026
mean_var=346.8726+/-77.541, 0's: 0 Z-trim(120.7): 1585 B-trim: 1961 in 1/54
Lambda= 0.068864
statistics sampled from 34193 (36201) to 34193 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.424), width: 16
Scan time: 8.600
The best scores are: opt bits E(85289)
NP_003404 (OMIM: 300265,306955,314390) zinc finger ( 467) 3303 342.3 1.7e-93
NP_001317590 (OMIM: 300265,306955,314390) zinc fin ( 457) 2912 303.4 8.2e-82
NP_003403 (OMIM: 600470,616602) zinc finger protei ( 447) 1790 192.0 2.9e-48
NP_009060 (OMIM: 603073,609637) zinc finger protei ( 532) 1720 185.1 4e-46
XP_011519412 (OMIM: 603073,609637) PREDICTED: zinc ( 427) 1577 170.8 6.6e-42
NP_115529 (OMIM: 608948) zinc finger protein ZIC 4 ( 334) 1346 147.7 4.6e-35
NP_001161851 (OMIM: 608948) zinc finger protein ZI ( 372) 1346 147.7 4.9e-35
NP_001161850 (OMIM: 608948) zinc finger protein ZI ( 384) 1346 147.8 5e-35
XP_016862803 (OMIM: 608948) PREDICTED: zinc finger ( 291) 922 105.5 2e-22
XP_011509275 (OMIM: 165230,610829,615849) PREDICTE (1461) 603 74.7 1.9e-12
XP_011509273 (OMIM: 165230,610829,615849) PREDICTE (1521) 603 74.8 1.9e-12
XP_011509272 (OMIM: 165230,610829,615849) PREDICTE (1539) 603 74.8 1.9e-12
XP_011509274 (OMIM: 165230,610829,615849) PREDICTE (1553) 603 74.8 1.9e-12
NP_005261 (OMIM: 165230,610829,615849) zinc finger (1586) 603 74.8 2e-12
XP_011509271 (OMIM: 165230,610829,615849) PREDICTE (1670) 603 74.8 2e-12
XP_011513576 (OMIM: 146510,165240,174200,174700,17 (1521) 600 74.5 2.3e-12
XP_016867486 (OMIM: 146510,165240,174200,174700,17 (1579) 600 74.5 2.4e-12
NP_000159 (OMIM: 146510,165240,174200,174700,17570 (1580) 600 74.5 2.4e-12
XP_011509276 (OMIM: 165230,610829,615849) PREDICTE (1444) 596 74.0 3e-12
XP_006712485 (OMIM: 165230,610829,615849) PREDICTE (1569) 596 74.1 3.1e-12
XP_016859307 (OMIM: 165230,610829,615849) PREDICTE (1653) 596 74.1 3.2e-12
XP_005251445 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 583 72.3 4.8e-12
XP_005251444 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 583 72.3 4.8e-12
XP_011516069 (OMIM: 610192,610199) PREDICTED: zinc ( 708) 583 72.3 4.8e-12
XP_016869850 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 583 72.4 5e-12
XP_011516068 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 583 72.4 5e-12
NP_689842 (OMIM: 610192,610199) zinc finger protei ( 775) 583 72.4 5e-12
XP_005251443 (OMIM: 610192,610199) PREDICTED: zinc ( 775) 583 72.4 5e-12
XP_011516067 (OMIM: 610192,610199) PREDICTED: zinc ( 868) 583 72.4 5.4e-12
NP_001035878 (OMIM: 610192,610199) zinc finger pro ( 930) 583 72.5 5.6e-12
XP_011516066 (OMIM: 610192,610199) PREDICTED: zinc ( 930) 583 72.5 5.6e-12
XP_011516065 (OMIM: 610192,610199) PREDICTED: zinc ( 930) 583 72.5 5.6e-12
NP_001161081 (OMIM: 165220) zinc finger protein GL (1065) 577 72.0 9.2e-12
NP_001153517 (OMIM: 165220) zinc finger protein GL ( 978) 576 71.8 9.4e-12
NP_005260 (OMIM: 165220) zinc finger protein GLI1 (1106) 577 72.0 9.4e-12
XP_011536491 (OMIM: 165220) PREDICTED: zinc finger (1106) 577 72.0 9.4e-12
NP_671726 (OMIM: 610378) zinc finger protein GLIS1 ( 620) 554 69.4 3.3e-11
XP_016855900 (OMIM: 610378) PREDICTED: zinc finger ( 629) 554 69.4 3.3e-11
XP_016855898 (OMIM: 610378) PREDICTED: zinc finger ( 791) 554 69.5 3.8e-11
XP_016855899 (OMIM: 610378) PREDICTED: zinc finger ( 795) 554 69.5 3.8e-11
XP_016855897 (OMIM: 610378) PREDICTED: zinc finger ( 795) 554 69.5 3.8e-11
XP_005253184 (OMIM: 603433) PREDICTED: zinc finger ( 435) 466 60.4 1.1e-08
XP_016873745 (OMIM: 603433) PREDICTED: zinc finger ( 606) 466 60.6 1.4e-08
NP_001269586 (OMIM: 603433) zinc finger protein 14 ( 607) 466 60.6 1.4e-08
XP_016873742 (OMIM: 603433) PREDICTED: zinc finger ( 621) 466 60.6 1.4e-08
XP_016873741 (OMIM: 603433) PREDICTED: zinc finger ( 622) 466 60.6 1.4e-08
XP_016873743 (OMIM: 603433) PREDICTED: zinc finger ( 637) 466 60.6 1.4e-08
XP_016873744 (OMIM: 603433) PREDICTED: zinc finger ( 637) 466 60.6 1.4e-08
NP_001269585 (OMIM: 603433) zinc finger protein 14 ( 637) 466 60.6 1.4e-08
NP_003433 (OMIM: 603433) zinc finger protein 143 i ( 638) 466 60.6 1.4e-08
>>NP_003404 (OMIM: 300265,306955,314390) zinc finger pro (467 aa)
initn: 3303 init1: 3303 opt: 3303 Z-score: 1799.6 bits: 342.3 E(85289): 1.7e-93
Smith-Waterman score: 3303; 100.0% identity (100.0% similar) in 467 aa overlap (1-467:1-467)
10 20 30 40 50 60
pF1KB7 MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSTHAAAAAAAAAAFKLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSTHAAAAAAAAAAFKLSP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AAAHDLSSGQSSAFTPQGSGYANALGHHHHHHHHHHHTSQVPSYGGAASAAFNSTREFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AAAHDLSSGQSSAFTPQGSGYANALGHHHHHHHHHHHTSQVPSYGGAASAAFNSTREFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 NNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHGPGAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHGPGAFF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 RYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHESQGSDSSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHESQGSDSSPA
370 380 390 400 410 420
430 440 450 460
pF1KB7 ASSGYESSTPPAIASANSKDTTKTPSAVQTSTSHNPGLPPNFNEWYV
:::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASSGYESSTPPAIASANSKDTTKTPSAVQTSTSHNPGLPPNFNEWYV
430 440 450 460
>>NP_001317590 (OMIM: 300265,306955,314390) zinc finger (457 aa)
initn: 2912 init1: 2912 opt: 2912 Z-score: 1589.8 bits: 303.4 E(85289): 8.2e-82
Smith-Waterman score: 2912; 100.0% identity (100.0% similar) in 408 aa overlap (1-408:1-408)
10 20 30 40 50 60
pF1KB7 MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSTHAAAAAAAAAAFKLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSTHAAAAAAAAAAFKLSP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 AAAHDLSSGQSSAFTPQGSGYANALGHHHHHHHHHHHTSQVPSYGGAASAAFNSTREFLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAAHDLSSGQSSAFTPQGSGYANALGHHHHHHHHHHHTSQVPSYGGAASAAFNSTREFLF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 NNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHGPGAFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHGPGAFF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 RYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 ECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHESQGSDSSPA
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKCCPAWYPGQSLI
370 380 390 400 410 420
430 440 450 460
pF1KB7 ASSGYESSTPPAIASANSKDTTKTPSAVQTSTSHNPGLPPNFNEWYV
NP_001 PDEELDTDVGMQQPALHNTTYPKCRVNAEPTVQEMIY
430 440 450
>>NP_003403 (OMIM: 600470,616602) zinc finger protein ZI (447 aa)
initn: 1851 init1: 1275 opt: 1790 Z-score: 987.5 bits: 192.0 E(85289): 2.9e-48
Smith-Waterman score: 2017; 64.5% identity (81.9% similar) in 476 aa overlap (3-467:1-447)
10 20 30 40 50
pF1KB7 MTMLLDGGPQFPGLGVGSFGAPRHH---EMPNREPAGMGLNPFGDSTHAAAAAAAAAAFK
::::.:::.:..:: .::: ::: .. .:. .:.:.:::.:. .:::
NP_003 MLLDAGPQYPAIGVTTFGASRHHSAGDVAERD-VGLGINPFADGM---------GAFK
10 20 30 40
60 70 80 90 100 110
pF1KB7 LSPAAAHDLSSGQSSAFTPQGSGYANA--LGHHHHHHHHHHHTSQVPSYGGAASAAFNST
:.:.. :.:.:. ..::: :. ::: : :::::: : : :: .:::::::
NP_003 LNPSS-HELASAGQTAFTSQAPGYAAAAALGHHHHPGH-------VGSY---SSAAFNST
50 60 70 80 90
120 130 140 150 160 170
pF1KB7 REFLFRQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSP
:.::::.:. : . ::....::.:::.::... .: : . ..:::::::::.::: ::
NP_003 RDFLFRNRGFG-DAAAAASAQHSLFAASAGGFGGPHGHTDAAGHLLFPGLHEQAAGHASP
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 TGHVDNNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHG
.: :.:..::. :... : . : :.:::.. ::: :. .:.:::.:: :::::
NP_003 --NVVNGQMRLGFSGDMYPRPEQYGQVTSPRSEHYAA-PQLHGYGPMNVNM----AAHHG
160 170 180 190 200
240 250 260 270 280 290
pF1KB7 PGAFFRYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNH
::::::::::::::: ::::. ::. :::::..:::::::::::::.::::::::.::
NP_003 AGAFFRYMRQPIKQELICKWIEPEQLANPKKSCNKTFSTMHELVTHVTVEHVGGPEQSNH
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB7 VCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGE
.:.::::::::: :::::::::::::::::::::::::::::.:::::::::::::::::
NP_003 ICFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGE
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB7 KPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKVHES--Q
:::::::::::::::::::::::::::::::::.::.:::::::::::::::::::: :
NP_003 KPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSYTHPSSLRKHMKVHESSSQ
330 340 350 360 370 380
420 430 440 450 460
pF1KB7 GSDSSPAASSGYESSTPPAIASANSKD-TTKTPSAVQTSTSHNPG---LPPNFNEWYV
::. ::::::::::::::.:.: .. . ::.. : .... :. : : :::::::
NP_003 GSQPSPAASSGYESSTPPTIVSPSTDNPTTSSLSPSSSAVHHTAGHSALSSNFNEWYV
390 400 410 420 430 440
>>NP_009060 (OMIM: 603073,609637) zinc finger protein ZI (532 aa)
initn: 1929 init1: 1152 opt: 1720 Z-score: 949.1 bits: 185.1 E(85289): 4e-46
Smith-Waterman score: 1926; 63.9% identity (79.1% similar) in 479 aa overlap (3-453:1-463)
10 20 30 40
pF1KB7 MTMLLDGGPQFPGLGVGSFGAPRHH----------EMPNREPA-GMGLNPFGDSTHAAAA
::::.:::::..:::::. .:: :: .:: . . . : : :: :
NP_009 MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDS-----A
10 20 30 40 50
50 60 70 80 90 100
pF1KB7 AAAAAAFKLSPAAAHDLSSGQSSAFTPQGSG-YANALGHHHHHHHHHHHTSQVPSYGGAA
:: .::::.:.: :.:: ::::::: :: : : .. . :...: ::.:
NP_009 AAHMGAFKLNPGA-HELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSGP-
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 SAAFNSTREFLFRQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQ
:::::.::::.: :....: ::::::::. .:..:: . . ..:::::: ::
NP_009 --PFNSTRDFLFRSR--GFGDSAPGGGQHGLFGPGAGGLHHAHS--DAQGHLLFPGLPEQ
120 130 140 150 160
170 180 190 200 210 220
pF1KB7 GAGHPSPTGHVDNNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPN-YSPMNMNMG
. : : .: :.:..::: ::.:::.. :: :::::::::.: ::. : :.:::::::
NP_009 HGPHGSQ--NVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSA-AQLHNQYGPMNMNMG
170 180 190 200 210 220
230 240 250 260 270
pF1KB7 VNVAA---------HHGPGAFFRYMRQP-IKQELSCKWIDEAQLSRPKKSCDRTFSTMHE
.:.:: :: :::::::::: ::::: ::::: ::: :::::..:::::::
NP_009 MNMAAAAAHHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHE
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB7 LVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGK
:::::..::::::::.::::.::::::::: :::::::::::::::::::::::::::::
NP_009 LVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGK
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB7 IFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSY
.::::::::::::::::::::.:::::::::::::::::::::::::::::.::.:::::
NP_009 VFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSY
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB7 THPSSLRKHMKVHES--QGSDSSPAASSGYESSTPPAIASANSKDTTKT---PSAVQTST
::::::::::::::: :::.:::::::::::::::...: ... ... :.:. ...
NP_009 THPSSLRKHMKVHESSPQGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAA
410 420 430 440 450 460
460
pF1KB7 SHNPGLPPNFNEWYV
.
NP_009 AAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSSGGGSGTAGGHSG
470 480 490 500 510 520
>>XP_011519412 (OMIM: 603073,609637) PREDICTED: zinc fin (427 aa)
initn: 1528 init1: 1124 opt: 1577 Z-score: 873.3 bits: 170.8 E(85289): 6.6e-42
Smith-Waterman score: 1783; 65.5% identity (78.8% similar) in 429 aa overlap (3-408:1-413)
10 20 30 40
pF1KB7 MTMLLDGGPQFPGLGVGSFGAPRHH----------EMPNREPA-GMGLNPFGDSTHAAAA
::::.:::::..:::::. .:: :: .:: . . . : : :: :
XP_011 MLLDAGPQFPAIGVGSFARHHHHSAAAAAAAAAEMQDRELSLAAAQNGFVDS-----A
10 20 30 40 50
50 60 70 80 90 100
pF1KB7 AAAAAAFKLSPAAAHDLSSGQSSAFTPQGSG-YANALGHHHHHHHHHHHTSQVPSYGGAA
:: .::::.:.: :.:: ::::::: :: : : .. . :...: ::.:
XP_011 AAHMGAFKLNPGA-HELSPGQSSAFTSQGPGAYPGSAAAAAAAAALGPHAAHVGSYSG--
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB7 SAAFNSTREFLFRQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQ
:::::.::::.: :....: ::::::::. .:..:: . . ..:::::: ::
XP_011 -PPFNSTRDFLFRSR--GFGDSAPGGGQHGLFGPGAGGLHHAHS--DAQGHLLFPGLPEQ
120 130 140 150 160
170 180 190 200 210 220
pF1KB7 GAGHPSPTGHVDNNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPN-YSPMNMNMG
. : : .: :.:..::: ::.:::.. :: :::::::::.: ::. : :.:::::::
XP_011 HGPHGSQ--NVLNGQMRLGLPGEVFGRSEQYRQVASPRTDPYSA-AQLHNQYGPMNMNMG
170 180 190 200 210 220
230 240 250 260 270
pF1KB7 VNVAA---------HHGPGAFFRYMRQP-IKQELSCKWIDEAQLSRPKKSCDRTFSTMHE
.:.:: :: :::::::::: ::::: ::::: ::: :::::..:::::::
XP_011 MNMAAAAAHHHHHHHHHPGAFFRYMRQQCIKQELICKWIDPEQLSNPKKSCNKTFSTMHE
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB7 LVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGK
:::::..::::::::.::::.::::::::: :::::::::::::::::::::::::::::
XP_011 LVTHVSVEHVGGPEQSNHVCFWEECPREGKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGK
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB7 IFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSY
.::::::::::::::::::::.:::::::::::::::::::::::::::::.::.:::::
XP_011 VFARSENLKIHKRTHTGEKPFQCEFEGCDRRFANSSDRKKHMHVHTSDKPYLCKMCDKSY
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB7 THPSSLRKHMKVHESQGSDSSPAASSGYESSTPPAIASANSKDTTKTPSAVQTSTSHNPG
:::::::::::
XP_011 THPSSLRKHMKSPLVPPPGFCLAGP
410 420
>>NP_115529 (OMIM: 608948) zinc finger protein ZIC 4 iso (334 aa)
initn: 1270 init1: 856 opt: 1346 Z-score: 750.4 bits: 147.7 E(85289): 4.6e-35
Smith-Waterman score: 1356; 60.9% identity (77.1% similar) in 340 aa overlap (120-453:13-330)
90 100 110 120 130 140
pF1KB7 HHHHHHHHTSQVPSYGGAASAAFNSTREFLFRQRSSGLSEAASGGGQHGLFAGSASSLHA
.: . :.:..:..:.:: .:::
NP_115 MRYKTSLVMRKRLRLYRNTLKESSSSSGHHGPQLTAASS---
10 20 30
150 160 170 180 190 200
pF1KB7 PAGIPEPPSYLLFPGLHEQGAGHPSPTGHVDNNQVHLGLRGELFGRADPYRPVASPRTDP
:: .::::::. . ::. . :. ..::: :....: .:. : . :.:
NP_115 -------PS--VFPGLHEEPP-QASPSRPL-NGLLRLGLPGDMYARPEPFPPGPAARSDA
40 50 60 70 80
210 220 230 240 250 260
pF1KB7 YAAGAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQPIKQELSCKWIDEAQLSRPKKSCD
::.: . .:. .::. ::.:: :::::::::::::::::: :::. . :. :.
NP_115 LAAAAALHGYG--GMNLTVNLAAPHGPGAFFRYMRQPIKQELICKWLAADGTATPSL-CS
90 100 110 120 130 140
270 280 290 300 310 320
pF1KB7 RTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFP
.:::::::::::::.:::::::: ::.:.::::::.:: :::::::::::::::::::::
NP_115 KTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFP
150 160 170 180 190 200
330 340 350 360 370 380
pF1KB7 CPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYI
::::::::.::::::::::::::::::::.::::::.:::::::::::: :::::::::
NP_115 CPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYT
210 220 230 240 250 260
390 400 410 420 430 440
pF1KB7 CKV--CDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYESSTPPAIASANS----KDTTK
::: ::: :::::::::::::: :: ::::.:.:: :..: .: :. .
NP_115 CKVRGCDKCYTHPSSLRKHMKVH-----GRSPPPSSGYDSATPSALVSPSSDCGHKSQVA
270 280 290 300 310 320
450 460
pF1KB7 TPSAVQTSTSHNPGLPPNFNEWYV
. .:: . :.
NP_115 SSAAVAARTADLSE
330
>>NP_001161851 (OMIM: 608948) zinc finger protein ZIC 4 (372 aa)
initn: 1270 init1: 856 opt: 1346 Z-score: 749.9 bits: 147.7 E(85289): 4.9e-35
Smith-Waterman score: 1357; 58.0% identity (75.0% similar) in 364 aa overlap (100-453:27-368)
70 80 90 100 110 120
pF1KB7 QSSAFTPQGSGYANALGHHHHHHHHHHHTSQVPSYGGAASAAFNSTREFLFRQR----SS
..: . : : . ...:.: .
NP_001 MNGPCQSLRKAEGLLEGCTSAVTVFRKLPLDSKAQSQKMRYKTSLVMRKRLRLYRN
10 20 30 40 50
130 140 150 160 170 180
pF1KB7 GLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVDNNQVH
:.:..:..:.:: .::: :: .::::::. . ::. . :. ..
NP_001 TLKESSSSSGHHGPQLTAASS----------PS--VFPGLHEEPP-QASPSRPL-NGLLR
60 70 80 90 100
190 200 210 220 230 240
pF1KB7 LGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQ
::: :....: .:. : . :.: ::.: . .:. ::.. ::.:: ::::::::::::
NP_001 LGLPGDMYARPEPFPPGPAARSDALAAAAALHGYGGMNLT--VNLAAPHGPGAFFRYMRQ
110 120 130 140 150 160
250 260 270 280 290 300
pF1KB7 PIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPRE
:::::: :::. . :. :..:::::::::::::.:::::::: ::.:.::::::.
NP_001 PIKQELICKWLAADGTATPSL-CSKTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQ
170 180 190 200 210
310 320 330 340 350 360
pF1KB7 GKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGC
:: :::::::::::::::::::::::::::::.::::::::::::::::::::.::::::
NP_001 GKPFKAKYKLVNHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGC
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB7 DRRFANSSDRKKHMHVHTSDKPYICKV--CDKSYTHPSSLRKHMKVHESQGSDSSPAASS
.:::::::::::: ::::::::: ::: ::: :::::::::::::: :: ::
NP_001 ERRFANSSDRKKHSHVHTSDKPYTCKVRGCDKCYTHPSSLRKHMKVH-----GRSPPPSS
280 290 300 310 320 330
430 440 450 460
pF1KB7 GYESSTPPAIASANS----KDTTKTPSAVQTSTSHNPGLPPNFNEWYV
::.:.:: :..: .: :. . . .:: . :.
NP_001 GYDSATPSALVSPSSDCGHKSQVASSAAVAARTADLSE
340 350 360 370
>>NP_001161850 (OMIM: 608948) zinc finger protein ZIC 4 (384 aa)
initn: 1270 init1: 856 opt: 1346 Z-score: 749.8 bits: 147.8 E(85289): 5e-35
Smith-Waterman score: 1356; 60.9% identity (77.1% similar) in 340 aa overlap (120-453:63-380)
90 100 110 120 130 140
pF1KB7 HHHHHHHHTSQVPSYGGAASAAFNSTREFLFRQRSSGLSEAASGGGQHGLFAGSASSLHA
.: . :.:..:..:.:: .:::
NP_001 LERIENNNTLWEKAQSQKMRYKTSLVMRKRLRLYRNTLKESSSSSGHHGPQLTAASS---
40 50 60 70 80
150 160 170 180 190 200
pF1KB7 PAGIPEPPSYLLFPGLHEQGAGHPSPTGHVDNNQVHLGLRGELFGRADPYRPVASPRTDP
:: .::::::. . ::. . :. ..::: :....: .:. : . :.:
NP_001 -------PS--VFPGLHEEPP-QASPSRPL-NGLLRLGLPGDMYARPEPFPPGPAARSDA
90 100 110 120 130
210 220 230 240 250 260
pF1KB7 YAAGAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQPIKQELSCKWIDEAQLSRPKKSCD
::.: . .:. .::. ::.:: :::::::::::::::::: :::. . :. :.
NP_001 LAAAAALHGYG--GMNLTVNLAAPHGPGAFFRYMRQPIKQELICKWLAADGTATPSL-CS
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB7 RTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFP
.:::::::::::::.:::::::: ::.:.::::::.:: :::::::::::::::::::::
NP_001 KTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFP
200 210 220 230 240 250
330 340 350 360 370 380
pF1KB7 CPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYI
::::::::.::::::::::::::::::::.::::::.:::::::::::: :::::::::
NP_001 CPFPGCGKVFARSENLKIHKRTHTGEKPFRCEFEGCERRFANSSDRKKHSHVHTSDKPYT
260 270 280 290 300 310
390 400 410 420 430 440
pF1KB7 CKV--CDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYESSTPPAIASANS----KDTTK
::: ::: :::::::::::::: :: ::::.:.:: :..: .: :. .
NP_001 CKVRGCDKCYTHPSSLRKHMKVH-----GRSPPPSSGYDSATPSALVSPSSDCGHKSQVA
320 330 340 350 360 370
450 460
pF1KB7 TPSAVQTSTSHNPGLPPNFNEWYV
. .:: . :.
NP_001 SSAAVAARTADLSE
380
>>XP_016862803 (OMIM: 608948) PREDICTED: zinc finger pro (291 aa)
initn: 994 init1: 580 opt: 922 Z-score: 523.4 bits: 105.5 E(85289): 2e-22
Smith-Waterman score: 932; 58.0% identity (76.5% similar) in 243 aa overlap (120-362:63-288)
90 100 110 120 130 140
pF1KB7 HHHHHHHHTSQVPSYGGAASAAFNSTREFLFRQRSSGLSEAASGGGQHGLFAGSASSLHA
.: . :.:..:..:.:: .:::
XP_016 LERIENNNTLWEKAQSQKMRYKTSLVMRKRLRLYRNTLKESSSSSGHHGPQLTAASS---
40 50 60 70 80
150 160 170 180 190 200
pF1KB7 PAGIPEPPSYLLFPGLHEQGAGHPSPTGHVDNNQVHLGLRGELFGRADPYRPVASPRTDP
:: .::::::. . ::. . :. ..::: :....: .:. : . :.:
XP_016 -------PS--VFPGLHEE-PPQASPSRPL-NGLLRLGLPGDMYARPEPFPPGPAARSDA
90 100 110 120 130
210 220 230 240 250 260
pF1KB7 YAAGAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQPIKQELSCKWIDEAQLSRPKKSCD
::.: . .:. .::. ::.:: :::::::::::::::::: :::. . :. :.
XP_016 LAAAAALHGYG--GMNLTVNLAAPHGPGAFFRYMRQPIKQELICKWLAADGTATPSL-CS
140 150 160 170 180 190
270 280 290 300 310 320
pF1KB7 RTFSTMHELVTHVTMEHVGGPEQNNHVCYWEECPREGKSFKAKYKLVNHIRVHTGEKPFP
.:::::::::::::.:::::::: ::.:.::::::.:: :::::::::::::::::::::
XP_016 KTFSTMHELVTHVTVEHVGGPEQANHICFWEECPRQGKPFKAKYKLVNHIRVHTGEKPFP
200 210 220 230 240 250
330 340 350 360 370 380
pF1KB7 CPFPGCGKIFARSENLKIHKRTHTGEKPFKCEFEGCDRRFANSSDRKKHMHVHTSDKPYI
::::::::.:::::::::::::::.: . .:
XP_016 CPFPGCGKVFARSENLKIHKRTHTAEAANRSKFLRS
260 270 280 290
390 400 410 420 430 440
pF1KB7 CKVCDKSYTHPSSLRKHMKVHESQGSDSSPAASSGYESSTPPAIASANSKDTTKTPSAVQ
>>XP_011509275 (OMIM: 165230,610829,615849) PREDICTED: z (1461 aa)
initn: 502 init1: 394 opt: 603 Z-score: 344.6 bits: 74.7 E(85289): 1.9e-12
Smith-Waterman score: 617; 32.6% identity (60.4% similar) in 371 aa overlap (103-453:147-508)
80 90 100 110 120 130
pF1KB7 AFTPQGSGYANALGHHHHHHHHHHHTSQVPSYGGAASAAFNSTREFLFRQRSSGLSEAAS
::: ...:.. . : : . . ..
XP_011 SLDLQRMIRTSPNSLVAYINNSRSSSAASGSYGHLSAGALSPA--FTFPHPINPVAYQQI
120 130 140 150 160 170
140 150 160 170 180
pF1KB7 GGGQHGLFAGSASSLHAPAGIPEPPSYLLF-PGLHEQGAGHPSPTGHV-----DNNQVHL
. :.:: ::: . :.: : :..: : . . :. . :.:: .
XP_011 LSQQRGL--GSAFG-HTPPLIQPSPTFLAQQPMALTSINATPTQLSSSSNCLSDTNQNKQ
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB7 GLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHGPGAFFRYMRQP
. .. . . ..: .. : . : ::. ...: .:..: . : . ..
XP_011 SSESAVSSTVNPVAIHKRSKVKTEPEGLR-PA-SPLALTQG-QVSGHGSCGCALPLSQEQ
240 250 260 270 280
250 260 270 280 290
pF1KB7 I---KQELS---CKWIDEAQLSRPK---KSCDRTFSTMHELVTHVTMEHVGGPEQNNHVC
. :..:. :: :. . . . ..: . ..:...:: :.. ::. : :... ::
XP_011 LADLKEDLDRDDCKQEAEVVIYETNCHWEDCTKEYDTQEQLVHHINNEHIHG-EKKEFVC
290 300 310 320 330 340
300 310 320 330 340 350
pF1KB7 YWEECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKP
:. : :: : :::.: :: :.: :::::: : : ::.: ..: :::: : :.::::::
XP_011 RWQACTREQKPFKAQYMLVVHMRRHTGEKPHKCTFEGCSKAYSRLENLKTHLRSHTGEKP
350 360 370 380 390 400
360 370 380 390 400 410
pF1KB7 FKCEFEGCDRRFANSSDRKKHMH-VHTSDKPYICKV--CDKSYTHPSSLRKHMKVHESQG
. :: :::.. :.:.::: ::.. .:...::::::. : : :: :::::::.:. ..
XP_011 YVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYICKIPGCTKRYTDPSSLRKHVKTVHGPD
410 420 430 440 450 460
420 430 440 450 460
pF1KB7 SDSSPAASSGYESSTPPAIASANSKDTTKT--PSAVQTSTSHNPGLPPNFNEWYV
. . . . :: ...:. :. : ....:..
XP_011 AHVTKKQRNDVHLRTPLLKENGDSEAGTEPGGPESTEASSTSQAVEDCLHVRAIKTESSG
470 480 490 500 510 520
XP_011 LCQSSPGAQSSCSSEPSPLGSAPNNDSGVEMPGTGPGSLGDLTALDDTPPGADTSALAAP
530 540 550 560 570 580
467 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:53:28 2016 done: Fri Nov 4 05:53:29 2016
Total Scan time: 8.600 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]