FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB7084, 127 aa
  1>>>pF1KB7084 127 - 127 aa - 127 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.2233+/-0.000311; mu= 10.3079+/- 0.019
 mean_var=54.7319+/-11.412, 0's: 0 Z-trim(115.8): 52  B-trim: 1404 in 1/54
 Lambda= 0.173362
 statistics sampled from 26460 (26502) to 26460 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.7), E-opt: 0.2 (0.311), width:  16
 Scan time:  4.540

The best scores are:                                      opt bits E(85289)
NP_036528 (OMIM: 607054) pleckstrin homology-like  ( 127)  827 214.4 3.9e-56
NP_003302 (OMIM: 602131) pleckstrin homology-like  ( 152)  368 99.7 1.7e-21
NP_031376 (OMIM: 605335) pleckstrin homology-like  ( 401)  170 50.3 3.2e-06


>>NP_036528 (OMIM: 607054) pleckstrin homology-like doma  (127 aa)
 initn: 827 init1: 827 opt: 827  Z-score: 1128.8  bits: 214.4 E(85289): 3.9e-56
Smith-Waterman score: 827; 100.0% identity (100.0% similar) in 127 aa overlap (1-127:1-127)

               10        20        30        40        50        60
pF1KB7 MTAAATATVLKEGVLEKRSGGLLQLWKRKRCVLTERGLQLFEAKGTGGRPKELSFARIKA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MTAAATATVLKEGVLEKRSGGLLQLWKRKRCVLTERGLQLFEAKGTGGRPKELSFARIKA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB7 VECVESTGRHIYFTLVTEGGGEIDFRCPLEDPGWNAQITLGLVKFKNQQAIQTVRARQSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VECVESTGRHIYFTLVTEGGGEIDFRCPLEDPGWNAQITLGLVKFKNQQAIQTVRARQSL
               70        80        90       100       110       120

              
pF1KB7 GTGTLVS
       :::::::
NP_036 GTGTLVS
              

>>NP_003302 (OMIM: 602131) pleckstrin homology-like doma  (152 aa)
 initn: 369 init1: 165 opt: 368  Z-score: 507.1  bits: 99.7 E(85289): 1.7e-21
Smith-Waterman score: 368; 55.5% identity (74.5% similar) in 110 aa overlap (9-118:7-114)

               10        20        30        40        50        60
pF1KB7 MTAAATATVLKEGVLEKRSGGLLQLWKRKRCVLTERGLQLFEAKGTGGRPKELSFARIKA
               ::.:: ::::: .:.::::.:: :::   :.:: :.  . ::::: :  :  
NP_003   MKSPDEVLREGELEKRSDSLFQLWKKKRGVLTSDRLSLFPASPRA-RPKELRFHSILK
                 10        20        30        40         50       

               70        80        90       100       110       120
pF1KB7 VECVESTGRHIYFTLVTEGGGEIDFRCPLEDPGWNAQITLGLVKFKNQQAIQTVRARQSL
       :.::: ::...:::.::    ::::::  :.  ::: :.:.:. :.:..:.:  :.::  
NP_003 VDCVERTGKYVYFTIVTTDHKEIDFRCAGES-CWNAAIALALIDFQNRRALQDFRSRQER
        60        70        80         90       100       110      

                                           
pF1KB7 GTGTLVS                             
                                           
NP_003 TAPAAPAEDAVAAAAAAPSEPSEPSRPSPQPKPRTP
        120       130       140       150  

>>NP_031376 (OMIM: 605335) pleckstrin homology-like doma  (401 aa)
 initn: 402 init1: 167 opt: 170  Z-score: 232.6  bits: 50.3 E(85289): 3.2e-06
Smith-Waterman score: 352; 43.9% identity (60.5% similar) in 157 aa overlap (1-118:142-297)

                                             10        20        30
pF1KB7                               MTAAATATVLKEGVLEKRSGGLLQLWKRKR
                                     :  ..   .:::::::::: :::::::.: 
NP_031 DGARLLLLPPARAAGNGEAEPSGGPSYAGRMLESSGCKALKEGVLEKRSDGLLQLWKKKC
             120       130       140       150       160       170 

               40                                50                
pF1KB7 CVLTERGLQLFEAK--------------------GTG----GRP--------------KE
       :.:::.:: :.  :                    : :    ..:              ::
NP_031 CILTEEGLLLIPPKQLQHQQQQQQQQQQQQQQQPGQGPAEPSQPSGPAVASLEPPVKLKE
             180       190       200       210       220       230 

             60        70        80        90       100       110  
pF1KB7 LSFARIKAVECVESTGRHIYFTLVTEGGGEIDFRCPLEDPGWNAQITLGLVKFKNQQAIQ
       : :. .:.:.:::  :...:::.:   : ::::::: .: ::::.::: .:..::.::: 
NP_031 LHFSNMKTVDCVERKGKYMYFTVVMAEGKEIDFRCP-QDQGWNAEITLQMVQYKNRQAIL
             240       250       260        270       280       290

             120                                                   
pF1KB7 TVRA-RQSLGTGTLVS                                            
       .:.. ::                                                     
NP_031 AVKSTRQKQQHLVQQQPPSQPQPQPQLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHP
              300       310       320       330       340       350




127 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 00:53:26 2016 done: Sat Nov  5 00:53:27 2016
 Total Scan time:  4.540 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]