Result of FASTA (omim) for
pF1KB6940
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6940, 229 aa
1>>>pF1KB6940 229 - 229 aa - 229 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0407+/-0.000362; mu= 15.2358+/- 0.022
mean_var=59.7630+/-12.130, 0's: 0 Z-trim(113.9): 44 B-trim: 549 in 1/50
Lambda= 0.165904
statistics sampled from 23460 (23473) to 23460 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.275), width: 16
Scan time: 6.400
The best scores are: opt bits E(85289)
NP_002563 (OMIM: 602508) platelet-activating facto ( 229) 1549 378.9 3.8e-105
XP_016873329 (OMIM: 602508) PREDICTED: platelet-ac ( 242) 1549 378.9 4e-105
NP_001296360 (OMIM: 602508) platelet-activating fa ( 181) 1205 296.5 1.9e-80
NP_002564 (OMIM: 603074) platelet-activating facto ( 231) 1040 257.1 1.8e-68
NP_001139412 (OMIM: 603074) platelet-activating fa ( 231) 1040 257.1 1.8e-68
NP_001139411 (OMIM: 603074) platelet-activating fa ( 231) 1040 257.1 1.8e-68
NP_001171675 (OMIM: 602508) platelet-activating fa ( 202) 940 233.1 2.6e-61
NP_001171676 (OMIM: 602508) platelet-activating fa ( 155) 934 231.6 5.7e-61
NP_001171677 (OMIM: 602508) platelet-activating fa ( 132) 906 224.9 5.2e-59
XP_016882335 (OMIM: 603074) PREDICTED: platelet-ac ( 218) 647 163.0 3.6e-40
XP_016882336 (OMIM: 603074) PREDICTED: platelet-ac ( 218) 647 163.0 3.6e-40
XP_016882337 (OMIM: 603074) PREDICTED: platelet-ac ( 218) 647 163.0 3.6e-40
>>NP_002563 (OMIM: 602508) platelet-activating factor ac (229 aa)
initn: 1549 init1: 1549 opt: 1549 Z-score: 2008.6 bits: 378.9 E(85289): 3.8e-105
Smith-Waterman score: 1549; 100.0% identity (100.0% similar) in 229 aa overlap (1-229:1-229)
10 20 30 40 50 60
pF1KB6 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
130 140 150 160 170 180
190 200 210 220
pF1KB6 HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
190 200 210 220
>>XP_016873329 (OMIM: 602508) PREDICTED: platelet-activa (242 aa)
initn: 1549 init1: 1549 opt: 1549 Z-score: 2008.3 bits: 378.9 E(85289): 4e-105
Smith-Waterman score: 1549; 100.0% identity (100.0% similar) in 229 aa overlap (1-229:14-242)
10 20 30 40
pF1KB6 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGD
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MCSERLVTCPRCRMSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGD
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 SMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SMVQLMQQYEIWRELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNH
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 ENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ENTAEEVAGGIEAIVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKL
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB6 ANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ANVQLLDTDGGFVHSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTT
190 200 210 220 230 240
pF1KB6 IA
::
XP_016 IA
>>NP_001296360 (OMIM: 602508) platelet-activating factor (181 aa)
initn: 1205 init1: 1205 opt: 1205 Z-score: 1565.2 bits: 296.5 E(85289): 1.9e-80
Smith-Waterman score: 1205; 100.0% identity (100.0% similar) in 181 aa overlap (49-229:1-181)
20 30 40 50 60 70
pF1KB6 QGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELFSPLHALNFGIGGDTT
::::::::::::::::::::::::::::::
NP_001 MVQLMQQYEIWRELFSPLHALNFGIGGDTT
10 20 30
80 90 100 110 120 130
pF1KB6 RHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQLINTRQPQAKIIVLG
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB6 LLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHDMFDFLHLT
100 110 120 130 140 150
200 210 220
pF1KB6 GGGYAKICKPLHELIMQLLEETPEEKQTTIA
:::::::::::::::::::::::::::::::
NP_001 GGGYAKICKPLHELIMQLLEETPEEKQTTIA
160 170 180
>>NP_002564 (OMIM: 603074) platelet-activating factor ac (231 aa)
initn: 1047 init1: 1031 opt: 1040 Z-score: 1350.2 bits: 257.1 E(85289): 1.8e-68
Smith-Waterman score: 1040; 65.3% identity (88.0% similar) in 216 aa overlap (4-219:3-218)
10 20 30 40 50 60
pF1KB6 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
:. :::. : ..:.::: :::: :.::: : :::::.:.:.:::.::::.: ::::
NP_002 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWR
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
:::::::::::::::: :.::::::.:::::.:.::..::::::::: .:::.:.:::.:
NP_002 ELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
::::.: :::::...::::::::..:::::.:: .::.:....: ...::.: :::
NP_002 IVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFV
120 130 140 150 160 170
190 200 210 220
pF1KB6 HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
::::.:: :::.:.:::. ::. .:. :: :...:: .
NP_002 HSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
180 190 200 210 220 230
>>NP_001139412 (OMIM: 603074) platelet-activating factor (231 aa)
initn: 1047 init1: 1031 opt: 1040 Z-score: 1350.2 bits: 257.1 E(85289): 1.8e-68
Smith-Waterman score: 1040; 65.3% identity (88.0% similar) in 216 aa overlap (4-219:3-218)
10 20 30 40 50 60
pF1KB6 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
:. :::. : ..:.::: :::: :.::: : :::::.:.:.:::.::::.: ::::
NP_001 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWR
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
:::::::::::::::: :.::::::.:::::.:.::..::::::::: .:::.:.:::.:
NP_001 ELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
::::.: :::::...::::::::..:::::.:: .::.:....: ...::.: :::
NP_001 IVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFV
120 130 140 150 160 170
190 200 210 220
pF1KB6 HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
::::.:: :::.:.:::. ::. .:. :: :...:: .
NP_001 HSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
180 190 200 210 220 230
>>NP_001139411 (OMIM: 603074) platelet-activating factor (231 aa)
initn: 1047 init1: 1031 opt: 1040 Z-score: 1350.2 bits: 257.1 E(85289): 1.8e-68
Smith-Waterman score: 1040; 65.3% identity (88.0% similar) in 216 aa overlap (4-219:3-218)
10 20 30 40 50 60
pF1KB6 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
:. :::. : ..:.::: :::: :.::: : :::::.:.:.:::.::::.: ::::
NP_001 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWR
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
:::::::::::::::: :.::::::.:::::.:.::..::::::::: .:::.:.:::.:
NP_001 ELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
::::.: :::::...::::::::..:::::.:: .::.:....: ...::.: :::
NP_001 IVQLVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFV
120 130 140 150 160 170
190 200 210 220
pF1KB6 HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
::::.:: :::.:.:::. ::. .:. :: :...:: .
NP_001 HSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
180 190 200 210 220 230
>>NP_001171675 (OMIM: 602508) platelet-activating factor (202 aa)
initn: 940 init1: 940 opt: 940 Z-score: 1221.7 bits: 233.1 E(85289): 2.6e-61
Smith-Waterman score: 940; 100.0% identity (100.0% similar) in 138 aa overlap (1-138:1-138)
10 20 30 40 50 60
pF1KB6 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
::::::::::::::::::
NP_001 IVQLINTRQPQAKIIVLGKAAASKYSISEIVRLEQGSVNWSIGTYPDDTPATTRPAILQL
130 140 150 160 170 180
>>NP_001171676 (OMIM: 602508) platelet-activating factor (155 aa)
initn: 932 init1: 932 opt: 934 Z-score: 1215.6 bits: 231.6 E(85289): 5.7e-61
Smith-Waterman score: 934; 92.1% identity (94.7% similar) in 151 aa overlap (1-151:1-151)
10 20 30 40 50 60
pF1KB6 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
::::::::::::::::: . . :. :.
NP_001 IVQLINTRQPQAKIIVLIIYWQDEQDYHERKVQMD
130 140 150
190 200 210 220
pF1KB6 HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
>>NP_001171677 (OMIM: 602508) platelet-activating factor (132 aa)
initn: 906 init1: 906 opt: 906 Z-score: 1180.5 bits: 224.9 E(85289): 5.2e-59
Smith-Waterman score: 906; 100.0% identity (100.0% similar) in 132 aa overlap (1-132:1-132)
10 20 30 40 50 60
pF1KB6 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
::::::::::::
NP_001 IVQLINTRQPQA
130
>>XP_016882335 (OMIM: 603074) PREDICTED: platelet-activa (218 aa)
initn: 964 init1: 647 opt: 647 Z-score: 842.2 bits: 163.0 E(85289): 3.6e-40
Smith-Waterman score: 937; 61.6% identity (82.4% similar) in 216 aa overlap (4-219:3-205)
10 20 30 40 50 60
pF1KB6 MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
:. :::. : ..:.::: :::: :.::: : :::::.:.:.:::.::::.: ::::
XP_016 MSGEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWR
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
:::::::::::::::: :.::::::.:::::.:.::..::::::::: .:::.:.:::.:
XP_016 ELFSPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
:::: ::::::..:::::.:: .::.:....: ...::.: :::
XP_016 IVQL-------------GLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFV
120 130 140 150 160
190 200 210 220
pF1KB6 HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
::::.:: :::.:.:::. ::. .:. :: :...:: .
XP_016 HSDGTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQDQGQGAPLLEPAP
170 180 190 200 210
229 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 17:45:17 2016 done: Sat Nov 5 17:45:18 2016
Total Scan time: 6.400 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]