Result of FASTA (omim) for
pF1KB6922
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6922, 227 aa
1>>>pF1KB6922 227 - 227 aa - 227 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1528+/-0.000297; mu= 15.5851+/- 0.019
mean_var=69.4866+/-13.369, 0's: 0 Z-trim(117.3): 11 B-trim: 0 in 0/55
Lambda= 0.153859
statistics sampled from 29237 (29246) to 29237 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.343), width: 16
Scan time: 7.040
The best scores are: opt bits E(85289)
NP_006849 (OMIM: 605395) transmembrane emp24 domai ( 227) 1483 337.6 1.1e-92
XP_006722694 (OMIM: 605395) PREDICTED: transmembra ( 189) 1073 246.5 2.3e-65
NP_057124 (OMIM: 616876) transmembrane emp24 domai ( 229) 814 189.1 5.4e-48
NP_001161302 (OMIM: 616876) transmembrane emp24 do ( 193) 552 130.8 1.5e-30
NP_872353 (OMIM: 612038) transmembrane emp24 domai ( 227) 159 43.7 0.00032
NP_001289991 (OMIM: 612038) transmembrane emp24 do ( 168) 157 43.1 0.00034
NP_001289990 (OMIM: 612038) transmembrane emp24 do ( 168) 157 43.1 0.00034
>>NP_006849 (OMIM: 605395) transmembrane emp24 domain-co (227 aa)
initn: 1483 init1: 1483 opt: 1483 Z-score: 1785.2 bits: 337.6 E(85289): 1.1e-92
Smith-Waterman score: 1483; 100.0% identity (100.0% similar) in 227 aa overlap (1-227:1-227)
10 20 30 40 50 60
pF1KB6 MMAAGAALALALWLLMPPVEVGGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MMAAGAALALALWLLMPPVEVGGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 QVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVF
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 FELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 FELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEA
130 140 150 160 170 180
190 200 210 220
pF1KB6 RDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT
:::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT
190 200 210 220
>>XP_006722694 (OMIM: 605395) PREDICTED: transmembrane e (189 aa)
initn: 1073 init1: 1073 opt: 1073 Z-score: 1294.5 bits: 246.5 E(85289): 2.3e-65
Smith-Waterman score: 1073; 100.0% identity (100.0% similar) in 167 aa overlap (61-227:23-189)
40 50 60 70 80 90
pF1KB6 DGEFTFLLPAGRKQCFYQSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKAD
::::::::::::::::::::::::::::::
XP_006 MRVEARGAATGTGWGGCGCAAVQVIGGAGLDVDFTLESPQGVLLVSESRKAD
10 20 30 40 50
100 110 120 130 140 150
pF1KB6 GVHTVEPTEAGDYKLCFDNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GVHTVEPTEAGDYKLCFDNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVK
60 70 80 90 100 110
160 170 180 190 200 210
pF1KB6 MEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVL
120 130 140 150 160 170
220
pF1KB6 QVCTLKRFFQDKRPVPT
:::::::::::::::::
XP_006 QVCTLKRFFQDKRPVPT
180
>>NP_057124 (OMIM: 616876) transmembrane emp24 domain-co (229 aa)
initn: 629 init1: 629 opt: 814 Z-score: 982.6 bits: 189.1 E(85289): 5.4e-48
Smith-Waterman score: 814; 58.1% identity (82.9% similar) in 210 aa overlap (16-223:17-225)
10 20 30 40 50
pF1KB6 MMAAGAALALALWLLMPPVEV-GGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLET
.::: . :.:: : :..::: ::::.:.:::: : .::::
NP_057 MGDKIWLPFPVLLLAALPPVLLPGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 EYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKL
::::. :::::.:: : ::.: :: :.::.::::::: ::.::: .::::.:::::::.
NP_057 EYQVLDGAGLDIDFHLASPEGKTLVFEQRKSDGVHTVE-TEVGDYMFCFDNTFSTISEKV
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 VFFELIFDSLQDD-EEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRA
.:::::.:.. .. .: : : . . ..::.:.::: :::.....:: .: .. :::::
NP_057 IFFELILDNMGEQAQEQEDWKKYITGTDILDMKLEDILESINSIKSRLSKSGHIQTLLRA
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 FEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT
:::::::.::.:..:::::: ::..:...:...:: :: .:.:::
NP_057 FEARDRNIQESNFDRVNFWSMVNLVVMVVVSAIQVYMLKSLFEDKRKSRT
180 190 200 210 220
>>NP_001161302 (OMIM: 616876) transmembrane emp24 domain (193 aa)
initn: 560 init1: 359 opt: 552 Z-score: 669.3 bits: 130.8 E(85289): 1.5e-30
Smith-Waterman score: 552; 57.9% identity (79.3% similar) in 145 aa overlap (16-158:17-160)
10 20 30 40 50
pF1KB6 MMAAGAALALALWLLMPPVEV-GGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLET
.::: . :.:: : :..::: ::::.:.:::: : .::::
NP_001 MGDKIWLPFPVLLLAALPPVLLPGAAGFTPSLDSDFTFTLPAGQKECFYQPMPLKASLEI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 EYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKL
::::. :::::.:: : ::.: :: :.::.::::::: ::.::: .::::.:::::::.
NP_001 EYQVLDGAGLDIDFHLASPEGKTLVFEQRKSDGVHTVE-TEVGDYMFCFDNTFSTISEKV
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 VFFELIFDSLQDD-EEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRA
.:::::.:.. .. .: : : . . ..::.:.::: . :
NP_001 IFFELILDNMGEQAQEQEDWKKYITGTDILDMKLEDILDPIIKIASDVQIRLHLGIHQQH
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 FEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT
NP_001 QVQTKQKWAHTNSA
180 190
>>NP_872353 (OMIM: 612038) transmembrane emp24 domain-co (227 aa)
initn: 117 init1: 84 opt: 159 Z-score: 196.9 bits: 43.7 E(85289): 0.00032
Smith-Waterman score: 159; 21.4% identity (52.7% similar) in 201 aa overlap (36-225:32-227)
10 20 30 40 50 60
pF1KB6 AALALALWLLMPPVEVGGAGPPPIQDGEFTFLLPAGRKQCFYQSAPANASLETEYQ----
: . .:.:: . : .. . .:.
NP_872 AGVGAGPLRAMGRQALLLLALCATGAQGLYFHIGETEKRCFIEEIPDETMVIGNYRTQMW
10 20 30 40 50 60
70 80 90 100 110
pF1KB6 -------VIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTI
. . :: . ...:.: ...:.. ..: : ::...:. ..
NP_872 DKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSN----
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 SEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTL
: ....: .. : .: : :: :. ... . . ..:. .
NP_872 STRMALFAGGKLRVHLDIQV-GEHANNYPEIAAKDKLTELQLRARQLLDQVEQIQKEQDY
120 130 140 150 160 170
180 190 200 210 220
pF1KB6 LRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT
: : : : .:.. .:: .:: .....:.:... :. :: ::. :. :
NP_872 QRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLKSFFEAKKLV
180 190 200 210 220
>>NP_001289991 (OMIM: 612038) transmembrane emp24 domain (168 aa)
initn: 116 init1: 84 opt: 157 Z-score: 196.3 bits: 43.1 E(85289): 0.00034
Smith-Waterman score: 157; 23.3% identity (56.0% similar) in 159 aa overlap (67-225:15-168)
40 50 60 70 80 90
pF1KB6 LLPAGRKQCFYQSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVE
:: . ...:.: ...:.. ..: :
NP_001 MWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFT
10 20 30 40
100 110 120 130 140 150
pF1KB6 PTEAGDYKLCFDNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKE
::...:. .. : ....: .. : .: : :: :. ...
NP_001 SHTPGDHQICLHSN----STRMALFAGGKLRVHLDIQV-GEHANNYPEIAAKDKLTELQL
50 60 70 80 90
160 170 180 190 200 210
pF1KB6 SIETMRTRLERSIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLK
. . ..:. . : : : : .:.. .:: .:: .....:.:... :. ::
NP_001 RARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLK
100 110 120 130 140 150
220
pF1KB6 RFFQDKRPVPT
::. :. :
NP_001 SFFEAKKLV
160
>>NP_001289990 (OMIM: 612038) transmembrane emp24 domain (168 aa)
initn: 116 init1: 84 opt: 157 Z-score: 196.3 bits: 43.1 E(85289): 0.00034
Smith-Waterman score: 157; 23.3% identity (56.0% similar) in 159 aa overlap (67-225:15-168)
40 50 60 70 80 90
pF1KB6 LLPAGRKQCFYQSAPANASLETEYQVIGGAGLDVDFTLESPQGVLLVSESRKADGVHTVE
:: . ...:.: ...:.. ..: :
NP_001 MWDKQKEVFLPSTPGLGMHVEVKDPDGKVVLSRQYGSEGRFTFT
10 20 30 40
100 110 120 130 140 150
pF1KB6 PTEAGDYKLCFDNSFSTISEKLVFFELIFDSLQDDEEVEGWAEAVEPEEMLDVKMEDIKE
::...:. .. : ....: .. : .: : :: :. ...
NP_001 SHTPGDHQICLHSN----STRMALFAGGKLRVHLDIQV-GEHANNYPEIAAKDKLTELQL
50 60 70 80 90
160 170 180 190 200 210
pF1KB6 SIETMRTRLERSIQMLTLLRAFEARDRNLQEGNLERVNFWSAVNVAVLLLVAVLQVCTLK
. . ..:. . : : : : .:.. .:: .:: .....:.:... :. ::
NP_001 RARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQRVLWWSIAQTVILILTGIWQMRHLK
100 110 120 130 140 150
220
pF1KB6 RFFQDKRPVPT
::. :. :
NP_001 SFFEAKKLV
160
227 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:24:00 2016 done: Sat Nov 5 14:24:01 2016
Total Scan time: 7.040 Total Display time: -0.040
Function used was FASTA [36.3.4 Apr, 2011]