FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6904, 223 aa
  1>>>pF1KB6904     223 - 223 aa - 223 aa
Library: human.CCDS.faa
  18921897 residues in 33420 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7651+/-0.00068; mu= 16.7348+/- 0.041
 mean_var=59.3967+/-11.703, 0's: 0 Z-trim(109.4): 21  B-trim: 0 in 0/51
 Lambda= 0.166415
 statistics sampled from 11018 (11029) to 11018 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.33), width:  16
 Scan time:  1.030

The best scores are:                                      opt bits E(33420)
CCDS2362.1 CTLA4 gene_id:1493|Hs109|chr2           ( 223) 1501 368.2 2.4e-102
CCDS42803.1 CTLA4 gene_id:1493|Hs109|chr2          ( 174) 1021 252.9 9.7e-68
CCDS2361.1 CD28 gene_id:940|Hs109|chr2             ( 220)  280 75.1 4.2e-14


>>CCDS2362.1 CTLA4 gene_id:1493|Hs109|chr2                (223 aa)
 initn: 1501 init1: 1501 opt: 1501  Z-score: 1951.1  bits: 368.2 E(33420): 2.4e-102
Smith-Waterman score: 1501; 99.6% identity (100.0% similar) in 223 aa overlap (1-223:1-223)

               10        20        30        40        50        60
pF1KB6 MACLGFQRHKAQLNLAARTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEY
       ::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
CCDS23 MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 ASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 ASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 AMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 AMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFL
              130       140       150       160       170       180

              190       200       210       220   
pF1KB6 LTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN
       :::::::::::::::::::::::::::::::::::::::::::
CCDS23 LTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN
              190       200       210       220   

>>CCDS42803.1 CTLA4 gene_id:1493|Hs109|chr2               (174 aa)
 initn: 1021 init1: 1021 opt: 1021  Z-score: 1329.8  bits: 252.9 E(33420): 9.7e-68
Smith-Waterman score: 1021; 96.8% identity (97.5% similar) in 158 aa overlap (1-158:1-158)

               10        20        30        40        50        60
pF1KB6 MACLGFQRHKAQLNLAARTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEY
       ::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::::
CCDS42 MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 ASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 ASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 AMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFL
       ::::::::::::::::::::::::::::::::  :  :                      
CCDS42 AMDTGLYICKVELMYPPPYYLGIGNGTQIYVIAKEKKPSYNRGLCENAPNRARM      
              130       140       150       160       170          

              190       200       210       220   
pF1KB6 LTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN

>>CCDS2361.1 CD28 gene_id:940|Hs109|chr2                  (220 aa)
 initn: 150 init1: 128 opt: 280  Z-score: 366.9  bits: 75.1 E(33420): 4.2e-14
Smith-Waterman score: 280; 31.0% identity (61.9% similar) in 210 aa overlap (24-221:5-212)

               10        20        30          40        50        
pF1KB6 MACLGFQRHKAQLNLAARTWPCTLLFFLLF--IPVFCKAMHVAQPAVVLASSRGIASFVC
                              :: . ::  : :  . . : :  ...: . .. .. :
CCDS23                    MLRLLLALNLFPSIQVTGNKILVKQSPMLVAYDNAV-NLSC
                                  10        20        30         40

       60        70        80        90       100         110      
pF1KB6 EYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDS--ICTGTSSGNQVNLTI
       .:.    . : :... .  :: : :::..   ....:   . .   : :  ....:.. .
CCDS23 KYSYNLFSREFRASLHKGLDSAV-EVCVVYGNYSQQLQVYSKTGFNCDGKLGNESVTFYL
               50        60         70        80        90         

        120       130       140        150       160            170
pF1KB6 QGLRAMDTGLYICKVELMYPPPYYLG-IGNGTQIYVIDPEPCPDSDFL-----LWILAAV
       :.: . .: .:.::.:.::::::  .  .::: :.:   . ::.  :      .:.:..:
CCDS23 QNLYVNQTDIYFCKIEVMYPPPYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKPFWVLVVV
     100       110       120       130       140       150         

              180       190        200        210       220        
pF1KB6 SSGLFFYSFLLTAVSLSKMLK-KRSPLTTGVYVKMPPTEP-ECEKQFQPYFIPIN     
       .. :  ::.:.:.. .   .. ::: :  . :..: : .:   .:..:::  :       
CCDS23 GGVLACYSLLVTVAFIIFWVRSKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPPRDFAAYR
     160       170       180       190       200       210         

CCDS23 S
     220




223 residues in 1 query   sequences
18921897 residues in 33420 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Thu Oct 24 21:38:19 2019 done: Thu Oct 24 21:38:19 2019
 Total Scan time:  1.030 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]