Result of FASTA (omim) for
pF1KB6657
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6657, 423 aa
1>>>pF1KB6657 423 - 423 aa - 423 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4012+/-0.000524; mu= 11.8864+/- 0.032
mean_var=181.6642+/-42.906, 0's: 0 Z-trim(112.0): 322 B-trim: 322 in 1/52
Lambda= 0.095157
statistics sampled from 20280 (20738) to 20280 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.602), E-opt: 0.2 (0.243), width: 16
Scan time: 8.290
The best scores are: opt bits E(85289)
NP_060726 (OMIM: 616620) ribosome biogenesis prote ( 423) 2855 405.3 1.5e-112
XP_011509771 (OMIM: 616620) PREDICTED: ribosome bi ( 285) 1851 267.3 3.6e-71
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 284 52.2 2.3e-06
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 284 52.2 2.3e-06
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 284 52.2 2.3e-06
NP_006089 (OMIM: 176981) receptor of activated pro ( 317) 270 50.3 8.4e-06
XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD re ( 540) 270 50.6 1.2e-05
NP_001013433 (OMIM: 606278) F-box/WD repeat-contai ( 589) 270 50.6 1.2e-05
NP_060785 (OMIM: 606278) F-box/WD repeat-containin ( 627) 270 50.7 1.3e-05
XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 270 50.7 1.3e-05
XP_011530388 (OMIM: 606278) PREDICTED: F-box/WD re ( 679) 270 50.7 1.3e-05
XP_011530387 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 270 50.7 1.4e-05
XP_011530386 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 270 50.7 1.4e-05
XP_016863851 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 270 50.7 1.4e-05
XP_011530385 (OMIM: 606278) PREDICTED: F-box/WD re ( 707) 270 50.7 1.4e-05
NP_361014 (OMIM: 606278) F-box/WD repeat-containin ( 707) 270 50.7 1.4e-05
NP_001128728 (OMIM: 602923) histone-binding protei ( 390) 265 49.7 1.5e-05
NP_001128727 (OMIM: 602923) histone-binding protei ( 424) 265 49.8 1.6e-05
NP_005601 (OMIM: 602923) histone-binding protein R ( 425) 265 49.8 1.6e-05
XP_011531867 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 261 48.9 1.7e-05
XP_011531865 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 261 48.9 1.7e-05
XP_011531866 (OMIM: 614783,614813) PREDICTED: POC1 ( 246) 261 48.9 1.7e-05
XP_011531864 (OMIM: 614783,614813) PREDICTED: POC1 ( 300) 261 49.0 1.9e-05
XP_011531863 (OMIM: 614783,614813) PREDICTED: POC1 ( 326) 261 49.1 2e-05
NP_001155052 (OMIM: 614783,614813) POC1 centriolar ( 359) 261 49.1 2.1e-05
XP_011531862 (OMIM: 614783,614813) PREDICTED: POC1 ( 374) 261 49.1 2.2e-05
NP_056241 (OMIM: 614783,614813) POC1 centriolar pr ( 407) 261 49.2 2.3e-05
NP_001309196 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 251 47.6 4.7e-05
NP_001309195 (OMIM: 607795,615922) U4/U6 small nuc ( 279) 251 47.6 4.7e-05
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 234 45.5 0.0003
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 234 45.5 0.0003
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 234 45.5 0.0003
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 234 45.5 0.0003
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 234 45.5 0.00031
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 234 45.5 0.00031
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 234 45.5 0.00031
NP_002884 (OMIM: 300825) histone-binding protein R ( 425) 232 45.2 0.00037
NP_001185648 (OMIM: 300825) histone-binding protei ( 469) 232 45.3 0.0004
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 229 44.7 0.00044
XP_016878353 (OMIM: 602703,616212) PREDICTED: kata ( 655) 232 45.5 0.00048
XP_016878352 (OMIM: 602703,616212) PREDICTED: kata ( 655) 232 45.5 0.00048
NP_005877 (OMIM: 602703,616212) katanin p80 WD40 r ( 655) 232 45.5 0.00048
XP_006721186 (OMIM: 602703,616212) PREDICTED: kata ( 658) 232 45.5 0.00049
XP_016878351 (OMIM: 602703,616212) PREDICTED: kata ( 672) 232 45.5 0.00049
XP_005255829 (OMIM: 602703,616212) PREDICTED: kata ( 672) 232 45.5 0.00049
XP_016878350 (OMIM: 602703,616212) PREDICTED: kata ( 672) 232 45.5 0.00049
XP_006721184 (OMIM: 602703,616212) PREDICTED: kata ( 675) 232 45.5 0.00049
XP_006721185 (OMIM: 602703,616212) PREDICTED: kata ( 675) 232 45.5 0.00049
XP_011521112 (OMIM: 602703,616212) PREDICTED: kata ( 675) 232 45.5 0.00049
XP_016878349 (OMIM: 602703,616212) PREDICTED: kata ( 675) 232 45.5 0.00049
>>NP_060726 (OMIM: 616620) ribosome biogenesis protein W (423 aa)
initn: 2855 init1: 2855 opt: 2855 Z-score: 2141.7 bits: 405.3 E(85289): 1.5e-112
Smith-Waterman score: 2855; 100.0% identity (100.0% similar) in 423 aa overlap (1-423:1-423)
10 20 30 40 50 60
pF1KB6 MAQLQTRFYTDNKKYAVDDVPFSIPAASEIADLSNIINKLLKDKNEFHKHVEFDFLIKGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MAQLQTRFYTDNKKYAVDDVPFSIPAASEIADLSNIINKLLKDKNEFHKHVEFDFLIKGQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 FLRMPLDKHMEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 FLRMPLDKHMEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 KTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 ALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 ALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EQLGLTRTPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EQLGLTRTPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 NCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 NCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLIS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 GSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSH
370 380 390 400 410 420
pF1KB6 VGA
:::
NP_060 VGA
>>XP_011509771 (OMIM: 616620) PREDICTED: ribosome biogen (285 aa)
initn: 1851 init1: 1851 opt: 1851 Z-score: 1398.7 bits: 267.3 E(85289): 3.6e-71
Smith-Waterman score: 1851; 99.3% identity (100.0% similar) in 274 aa overlap (150-423:12-285)
120 130 140 150 160 170
pF1KB6 DKTSRIWSLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKV
..::::::::::::::::::::::::::::
XP_011 MMTGSVQLKGQRNDSLSCLLLSASMDQTILLWEWNVERNKV
10 20 30 40
180 190 200 210 220 230
pF1KB6 KALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQK
50 60 70 80 90 100
240 250 260 270 280 290
pF1KB6 TEQLGLTRTPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEQLGLTRTPIVTLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKV
110 120 130 140 150 160
300 310 320 330 340 350
pF1KB6 FNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNCISYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLI
170 180 190 200 210 220
360 370 380 390 400 410
pF1KB6 SGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTS
230 240 250 260 270 280
420
pF1KB6 HVGA
::::
XP_011 HVGA
>>NP_060058 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 216 init1: 98 opt: 284 Z-score: 235.3 bits: 52.2 E(85289): 2.3e-06
Smith-Waterman score: 330; 29.2% identity (55.6% similar) in 277 aa overlap (100-370:44-286)
70 80 90 100 110 120
pF1KB6 MEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAE--EWILTGSYDKTSRIW-
: .::.: . ::. ..: :: .::
NP_060 RAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG
20 30 40 50 60 70
130 140 150 160 170 180
pF1KB6 SLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCR
. .:: :: :: ..:::: .: : ::.::: :.:. .: . .. : :. .
NP_060 AYDGKFEKTISGHKLGISDVAW---SSDSNLLVSASDDKTLKIW----DVSSGKCLKTLK
80 90 100 110 120
190 200 210 220 230 240
pF1KB6 GHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLT
::.. : . ... . :::.:. ..::.. .:.. :
NP_060 GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV-----------KTGKCLK----------
130 140 150 160
250 260 270 280 290 300
pF1KB6 RTPIVTLSGHMEAVSSVLWS-DAEEICSASWDHTIRVWDVESGSLKSTLTG--NKVFNCI
:: .: . ::.: .. :. : :.:.: :.::. ::. .:: : . .
NP_060 -----TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB6 SYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSL
..:: : . ... : ..::: .: : . . .. . ...: : . ..:::
NP_060 KFSPNGKYILAATLDNTLKLWD-YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE
230 240 250 260 270
370 380 390 400 410 420
pF1KB6 DNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA
::.: .:
NP_060 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
280 290 300 310 320 330
>>NP_438172 (OMIM: 609012) WD repeat-containing protein (334 aa)
initn: 216 init1: 98 opt: 284 Z-score: 235.3 bits: 52.2 E(85289): 2.3e-06
Smith-Waterman score: 330; 29.2% identity (55.6% similar) in 277 aa overlap (100-370:44-286)
70 80 90 100 110 120
pF1KB6 MEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAE--EWILTGSYDKTSRIW-
: .::.: . ::. ..: :: .::
NP_438 RAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG
20 30 40 50 60 70
130 140 150 160 170 180
pF1KB6 SLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCR
. .:: :: :: ..:::: .: : ::.::: :.:. .: . .. : :. .
NP_438 AYDGKFEKTISGHKLGISDVAW---SSDSNLLVSASDDKTLKIW----DVSSGKCLKTLK
80 90 100 110 120
190 200 210 220 230 240
pF1KB6 GHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLT
::.. : . ... . :::.:. ..::.. .:.. :
NP_438 GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV-----------KTGKCLK----------
130 140 150 160
250 260 270 280 290 300
pF1KB6 RTPIVTLSGHMEAVSSVLWS-DAEEICSASWDHTIRVWDVESGSLKSTLTG--NKVFNCI
:: .: . ::.: .. :. : :.:.: :.::. ::. .:: : . .
NP_438 -----TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB6 SYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSL
..:: : . ... : ..::: .: : . . .. . ...: : . ..:::
NP_438 KFSPNGKYILAATLDNTLKLWD-YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE
230 240 250 260 270
370 380 390 400 410 420
pF1KB6 DNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA
::.: .:
NP_438 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
280 290 300 310 320 330
>>XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-conta (334 aa)
initn: 216 init1: 98 opt: 284 Z-score: 235.3 bits: 52.2 E(85289): 2.3e-06
Smith-Waterman score: 330; 29.2% identity (55.6% similar) in 277 aa overlap (100-370:44-286)
70 80 90 100 110 120
pF1KB6 MEMENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAE--EWILTGSYDKTSRIW-
: .::.: . ::. ..: :: .::
XP_005 RAQPTPSSSATQSKPTPVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG
20 30 40 50 60 70
130 140 150 160 170 180
pF1KB6 SLEGKSIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCR
. .:: :: :: ..:::: .: : ::.::: :.:. .: . .. : :. .
XP_005 AYDGKFEKTISGHKLGISDVAW---SSDSNLLVSASDDKTLKIW----DVSSGKCLKTLK
80 90 100 110 120
190 200 210 220 230 240
pF1KB6 GHAGSVDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLT
::.. : . ... . :::.:. ..::.. .:.. :
XP_005 GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDV-----------KTGKCLK----------
130 140 150 160
250 260 270 280 290 300
pF1KB6 RTPIVTLSGHMEAVSSVLWS-DAEEICSASWDHTIRVWDVESGSLKSTLTG--NKVFNCI
:: .: . ::.: .. :. : :.:.: :.::. ::. .:: : . .
XP_005 -----TLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFV
170 180 190 200 210 220
310 320 330 340 350 360
pF1KB6 SYSPLCKRLASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSL
..:: : . ... : ..::: .: : . . .. . ...: : . ..:::
XP_005 KFSPNGKYILAATLDNTLKLWD-YSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSE
230 240 250 260 270
370 380 390 400 410 420
pF1KB6 DNIVKLWDTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA
::.: .:
XP_005 DNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLWKSDC
280 290 300 310 320 330
>>NP_006089 (OMIM: 176981) receptor of activated protein (317 aa)
initn: 148 init1: 99 opt: 270 Z-score: 225.2 bits: 50.3 E(85289): 8.4e-06
Smith-Waterman score: 274; 29.8% identity (56.1% similar) in 228 aa overlap (186-408:12-215)
160 170 180 190 200 210
pF1KB6 CLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGS-GTKFCSGSWDKMLK
.:: : : .::. . . :.: :: .
NP_006 MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTII
10 20 30 40
220 230 240 250 260 270
pF1KB6 IWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWS-DAEEICS
.:. . .:: :: :. : .: :: . ::.:. : :.. :
NP_006 MWKLT----RDE----TNY----------GI---PQRALRGHSHFVSDVVISSDGQFALS
50 60 70 80
280 290 300 310 320 330
pF1KB6 ASWDHTIRVWDVESGSLKSTLTGN-KVFNCISYSPLCKRLASGSTDRHIRLWDPRTKDGS
.::: :.:.::. .:. ..:. : ...: ....::: :. :.::. :
NP_006 GSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN--TLGVC
90 100 110 120 130
340 350 360 370 380 390
pF1KB6 LVSLSLTSHTGWVTSVKWSPTHEQQLI-SGSLDNIVKLWDTRSCKAPLYDLAAHEDKVLS
... ::. ::. :..::. . .: : . :..::.:. .:: .. : . .
NP_006 KYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIG-HTGYLNT
140 150 160 170 180 190
400 410 420
pF1KB6 VDWTDTG-LLLSGGADNKLYSYRYSPTTSHVGA
: . : : ::: :..
NP_006 VTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIK
200 210 220 230 240 250
>>XP_011530390 (OMIM: 606278) PREDICTED: F-box/WD repeat (540 aa)
initn: 273 init1: 82 opt: 270 Z-score: 222.6 bits: 50.6 E(85289): 1.2e-05
Smith-Waterman score: 334; 30.3% identity (57.3% similar) in 274 aa overlap (103-374:258-486)
80 90 100 110 120 130
pF1KB6 ENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYDKTSRIWSLE-GK
: :... .. :..:: :.: ..:. : :.
XP_011 VSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGE
230 240 250 260 270 280
140 150 160 170 180 190
pF1KB6 SIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGS
: :. :::..:. . .: ..:.: : :. .:. .: .. :: ::...
XP_011 CIHTLYGHTSTVRCMHLHEKR-----VVSGSRDATLRVWD--IETGQC--LHVLMGHVAA
290 300 310 320 330
200 210 220 230 240 250
pF1KB6 VDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIV
: . :: . ::..: :.:.: : : : : .
XP_011 VRCVQYDGR--RVVSGAYDFMVKVW-----DPETE---------------------TCLH
340 350 360
260 270 280 290 300 310
pF1KB6 TLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKR
::.:: . : : : :. .. :.: : .:::::::.:. ::::.. .. : :
XP_011 TLQGHTNRVYS-LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT--SGMELKDN
370 380 390 400 410 420
320 330 340 350 360 370
pF1KB6 -LASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW
:.::..: ...:: .: . . . ..: . :: .... . .:..: :. ::::
XP_011 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF---VITSSDDGTVKLW
430 440 450 460 470 480
380 390 400 410 420
pF1KB6 DTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA
: ..
XP_011 DLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
490 500 510 520 530 540
>>NP_001013433 (OMIM: 606278) F-box/WD repeat-containing (589 aa)
initn: 329 init1: 82 opt: 270 Z-score: 222.2 bits: 50.6 E(85289): 1.2e-05
Smith-Waterman score: 334; 30.3% identity (57.3% similar) in 274 aa overlap (103-374:307-535)
80 90 100 110 120 130
pF1KB6 ENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYDKTSRIWSLE-GK
: :... .. :..:: :.: ..:. : :.
NP_001 VSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGE
280 290 300 310 320 330
140 150 160 170 180 190
pF1KB6 SIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGS
: :. :::..:. . .: ..:.: : :. .:. .: .. :: ::...
NP_001 CIHTLYGHTSTVRCMHLHEKR-----VVSGSRDATLRVWD--IETGQC--LHVLMGHVAA
340 350 360 370 380
200 210 220 230 240 250
pF1KB6 VDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIV
: . :: . ::..: :.:.: : : : : .
NP_001 VRCVQYDGR--RVVSGAYDFMVKVW-----DPETE---------------------TCLH
390 400 410
260 270 280 290 300 310
pF1KB6 TLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKR
::.:: . : : : :. .. :.: : .:::::::.:. ::::.. .. : :
NP_001 TLQGHTNRVYS-LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT--SGMELKDN
420 430 440 450 460 470
320 330 340 350 360 370
pF1KB6 -LASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW
:.::..: ...:: .: . . . ..: . :: .... . .:..: :. ::::
NP_001 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF---VITSSDDGTVKLW
480 490 500 510 520 530
380 390 400 410 420
pF1KB6 DTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA
: ..
NP_001 DLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
540 550 560 570 580
>>NP_060785 (OMIM: 606278) F-box/WD repeat-containing pr (627 aa)
initn: 275 init1: 82 opt: 270 Z-score: 221.9 bits: 50.7 E(85289): 1.3e-05
Smith-Waterman score: 334; 30.3% identity (57.3% similar) in 274 aa overlap (103-374:345-573)
80 90 100 110 120 130
pF1KB6 ENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYDKTSRIWSLE-GK
: :... .. :..:: :.: ..:. : :.
NP_060 VSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGE
320 330 340 350 360 370
140 150 160 170 180 190
pF1KB6 SIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGS
: :. :::..:. . .: ..:.: : :. .:. .: .. :: ::...
NP_060 CIHTLYGHTSTVRCMHLHEKR-----VVSGSRDATLRVWD--IETGQC--LHVLMGHVAA
380 390 400 410 420
200 210 220 230 240 250
pF1KB6 VDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIV
: . :: . ::..: :.:.: : : : : .
NP_060 VRCVQYDGR--RVVSGAYDFMVKVW-----DPETE---------------------TCLH
430 440 450
260 270 280 290 300 310
pF1KB6 TLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKR
::.:: . : : : :. .. :.: : .:::::::.:. ::::.. .. : :
NP_060 TLQGHTNRVYS-LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT--SGMELKDN
460 470 480 490 500 510
320 330 340 350 360 370
pF1KB6 -LASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW
:.::..: ...:: .: . . . ..: . :: .... . .:..: :. ::::
NP_060 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF---VITSSDDGTVKLW
520 530 540 550 560
380 390 400 410 420
pF1KB6 DTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA
: ..
NP_060 DLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
570 580 590 600 610 620
>>XP_011530389 (OMIM: 606278) PREDICTED: F-box/WD repeat (679 aa)
initn: 329 init1: 82 opt: 270 Z-score: 221.6 bits: 50.7 E(85289): 1.3e-05
Smith-Waterman score: 334; 30.3% identity (57.3% similar) in 274 aa overlap (103-374:397-625)
80 90 100 110 120 130
pF1KB6 ENISSEEVVEIEYVEKYTAPQPEQCMFHDDWISSIKGAEEWILTGSYDKTSRIWSLE-GK
: :... .. :..:: :.: ..:. : :.
XP_011 VSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMR--DNIIISGSTDRTLKVWNAETGE
370 380 390 400 410 420
140 150 160 170 180 190
pF1KB6 SIMTIVGHTDVVKDVAWVKKDSLSCLLLSASMDQTILLWEWNVERNKVKALHCCRGHAGS
: :. :::..:. . .: ..:.: : :. .:. .: .. :: ::...
XP_011 CIHTLYGHTSTVRCMHLHEKR-----VVSGSRDATLRVWD--IETGQC--LHVLMGHVAA
430 440 450 460 470
200 210 220 230 240 250
pF1KB6 VDSIAVDGSGTKFCSGSWDKMLKIWSTVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIV
: . :: . ::..: :.:.: : : : : .
XP_011 VRCVQYDGR--RVVSGAYDFMVKVW-----DPETE---------------------TCLH
480 490 500
260 270 280 290 300 310
pF1KB6 TLSGHMEAVSSVLWSDAEEICSASWDHTIRVWDVESGSLKSTLTGNKVFNCISYSPLCKR
::.:: . : : : :. .. :.: : .:::::::.:. ::::.. .. : :
XP_011 TLQGHTNRVYS-LQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLT--SGMELKDN
510 520 530 540 550 560
320 330 340 350 360 370
pF1KB6 -LASGSTDRHIRLWDPRTKDGSLVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLW
:.::..: ...:: .: . . . ..: . :: .... . .:..: :. ::::
XP_011 ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNF---VITSSDDGTVKLW
570 580 590 600 610 620
380 390 400 410 420
pF1KB6 DTRSCKAPLYDLAAHEDKVLSVDWTDTGLLLSGGADNKLYSYRYSPTTSHVGA
: ..
XP_011 DLKTGEFIRNLVTLESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDMK
630 640 650 660 670
423 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:17:12 2016 done: Sat Nov 5 11:17:13 2016
Total Scan time: 8.290 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]