Result of FASTA (omim) for
pF1KB6616
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6616, 433 aa
1>>>pF1KB6616 433 - 433 aa - 433 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5025+/-0.000465; mu= 2.7993+/- 0.028
mean_var=420.4625+/-94.493, 0's: 0 Z-trim(119.1): 1901 B-trim: 0 in 0/52
Lambda= 0.062548
statistics sampled from 30151 (32682) to 30151 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.733), E-opt: 0.2 (0.383), width: 16
Scan time: 7.820
The best scores are: opt bits E(85289)
NP_000446 (OMIM: 175200,260350,273300,602216) seri ( 433) 2940 280.1 7.6e-75
XP_005259675 (OMIM: 175200,260350,273300,602216) P ( 404) 2554 245.2 2.2e-64
XP_005259674 (OMIM: 175200,260350,273300,602216) P ( 600) 2528 243.2 1.4e-63
XP_011526511 (OMIM: 175200,260350,273300,602216) P ( 526) 1902 186.6 1.3e-46
NP_006242 (OMIM: 602739) 5'-AMP-activated protein ( 559) 599 69.0 3.4e-11
NP_006243 (OMIM: 600497) 5'-AMP-activated protein ( 552) 574 66.8 1.6e-10
NP_996790 (OMIM: 602739) 5'-AMP-activated protein ( 574) 559 65.5 4.2e-10
XP_016865114 (OMIM: 602739) PREDICTED: 5'-AMP-acti ( 533) 526 62.4 3.2e-09
NP_115806 (OMIM: 609235) serine/threonine-protein ( 778) 527 62.8 3.6e-09
NP_001269147 (OMIM: 609236) serine/threonine-prote ( 614) 522 62.2 4.4e-09
XP_011518764 (OMIM: 609236) PREDICTED: serine/thre ( 660) 522 62.2 4.6e-09
NP_003948 (OMIM: 609236) serine/threonine-protein ( 668) 522 62.2 4.6e-09
NP_001243558 (OMIM: 609236) serine/threonine-prote ( 674) 522 62.2 4.6e-09
XP_011518763 (OMIM: 609236) PREDICTED: serine/thre ( 676) 522 62.2 4.6e-09
XP_006718439 (OMIM: 609236) PREDICTED: serine/thre ( 698) 522 62.2 4.7e-09
XP_005253275 (OMIM: 609236) PREDICTED: serine/thre ( 720) 522 62.3 4.8e-09
NP_001243556 (OMIM: 609236) serine/threonine-prote ( 736) 522 62.3 4.8e-09
XP_016874026 (OMIM: 609236) PREDICTED: serine/thre ( 752) 522 62.3 4.9e-09
XP_006718437 (OMIM: 609236) PREDICTED: serine/thre ( 758) 522 62.3 4.9e-09
NP_001243559 (OMIM: 609236) serine/threonine-prote ( 766) 522 62.3 4.9e-09
XP_016874024 (OMIM: 609236) PREDICTED: serine/thre ( 798) 522 62.3 5.1e-09
XP_016874023 (OMIM: 609236) PREDICTED: serine/thre ( 804) 522 62.3 5.1e-09
XP_016874021 (OMIM: 609236) PREDICTED: serine/thre ( 820) 522 62.4 5.1e-09
XP_016874025 (OMIM: 609236) PREDICTED: serine/thre ( 858) 522 62.4 5.2e-09
XP_016874022 (OMIM: 609236) PREDICTED: serine/thre ( 880) 522 62.4 5.3e-09
XP_011516388 (OMIM: 607025) PREDICTED: maternal em ( 373) 513 61.0 5.9e-09
XP_011516382 (OMIM: 607025) PREDICTED: maternal em ( 622) 514 61.4 7.3e-09
NP_001243614 (OMIM: 607025) maternal embryonic leu ( 610) 513 61.3 7.7e-09
NP_055606 (OMIM: 607025) maternal embryonic leucin ( 651) 513 61.4 8e-09
XP_011516380 (OMIM: 607025) PREDICTED: maternal em ( 651) 513 61.4 8e-09
XP_011516381 (OMIM: 607025) PREDICTED: maternal em ( 651) 513 61.4 8e-09
XP_011516378 (OMIM: 607025) PREDICTED: maternal em ( 651) 513 61.4 8e-09
XP_011516379 (OMIM: 607025) PREDICTED: maternal em ( 651) 513 61.4 8e-09
XP_011527839 (OMIM: 606532) PREDICTED: hormonally ( 698) 511 61.3 9.4e-09
NP_055401 (OMIM: 606532) hormonally up-regulated n ( 714) 511 61.3 9.5e-09
NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780) 505 60.8 1.4e-08
XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 505 60.8 1.4e-08
XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788) 505 60.8 1.5e-08
NP_061120 (OMIM: 606511) serine/threonine-protein ( 795) 505 60.8 1.5e-08
NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 505 60.8 1.5e-08
XP_006711389 (OMIM: 606511) PREDICTED: serine/thre ( 708) 501 60.4 1.8e-08
NP_004064 (OMIM: 602913) serine/threonine-protein ( 646) 490 59.3 3.3e-08
XP_016865113 (OMIM: 602739) PREDICTED: 5'-AMP-acti ( 548) 483 58.6 4.7e-08
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 481 58.5 5.9e-08
NP_006733 (OMIM: 177015) serine/threonine-protein ( 424) 477 57.9 6e-08
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 481 58.6 6.3e-08
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 481 58.6 6.3e-08
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 481 58.6 6.3e-08
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 481 58.6 6.3e-08
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 481 58.6 6.4e-08
>>NP_000446 (OMIM: 175200,260350,273300,602216) serine/t (433 aa)
initn: 2940 init1: 2940 opt: 2940 Z-score: 1464.7 bits: 280.1 E(85289): 7.6e-75
Smith-Waterman score: 2940; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KB6 MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 RQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 IYTQDFTVPGQVPEEEASHNGQRRGLPKAVCMNGTEAAQLSTKSRAEGRAPNPARKACSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IYTQDFTVPGQVPEEEASHNGQRRGLPKAVCMNGTEAAQLSTKSRAEGRAPNPARKACSA
370 380 390 400 410 420
430
pF1KB6 SSKIRRLSACKQQ
:::::::::::::
NP_000 SSKIRRLSACKQQ
430
>>XP_005259675 (OMIM: 175200,260350,273300,602216) PREDI (404 aa)
initn: 2561 init1: 2530 opt: 2554 Z-score: 1276.8 bits: 245.2 E(85289): 2.2e-64
Smith-Waterman score: 2554; 95.0% identity (96.5% similar) in 403 aa overlap (1-399:1-400)
10 20 30 40 50 60
pF1KB6 MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 RQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDI
310 320 330 340 350 360
370 380 390 400 410
pF1KB6 IYTQDFTVPGQVPEEEASHNGQR--RGLPKAVC--MNGTEAAQLSTKSRAEGRAPNPARK
:::::::::: ::::. : : ::: :. ..: ::..
XP_005 IYTQDFTVPGG---EEASEAGLRAERGLQKSEGSDLSGEEASRPAPQ
370 380 390 400
420 430
pF1KB6 ACSASSKIRRLSACKQQ
>>XP_005259674 (OMIM: 175200,260350,273300,602216) PREDI (600 aa)
initn: 2522 init1: 2522 opt: 2528 Z-score: 1262.4 bits: 243.2 E(85289): 1.4e-63
Smith-Waterman score: 2528; 91.0% identity (95.2% similar) in 413 aa overlap (1-413:1-411)
10 20 30 40 50 60
pF1KB6 MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEVVDPQQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKQKMYMVMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 NLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 RQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 IYTQDFTVPGQVPEEEASHNGQRRGLPKAVCMNGTEAAQLSTKSRAEGRAPNPARKACSA
:::::::::: :.. .. . : :.. .. ... . .. : .:.:
XP_005 IYTQDFTVPG--PRRGGQSQWTAPGPPQGRVYERHRGGAAEHQIQGGGPGPQPCPQGLLR
370 380 390 400 410
430
pF1KB6 SSKIRRLSACKQQ
XP_005 QQQDPPAVGLQAAVRLAACSPCPGAPPGARARPSVFLPVPPALPERWPPCFCADHAPGPP
420 430 440 450 460 470
>>XP_011526511 (OMIM: 175200,260350,273300,602216) PREDI (526 aa)
initn: 1896 init1: 1896 opt: 1902 Z-score: 957.7 bits: 186.6 E(85289): 1.3e-46
Smith-Waterman score: 1902; 88.3% identity (93.7% similar) in 316 aa overlap (98-413:24-337)
70 80 90 100 110 120
pF1KB6 DSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYM
::::::::::::::::::::::::::::::
XP_011 MGSCRPGAVTHESKRSRPSWPTWEIQLLRRLRHKNVIQLVDVLYNEEKQKMYM
10 20 30 40 50
130 140 150 160 170 180
pF1KB6 VMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VMEYCVCGMQEMLDSVPEKRFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTG
60 70 80 90 100 110
190 200 210 220 230 240
pF1KB6 GTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYN
120 130 140 150 160 170
250 260 270 280 290 300
pF1KB6 ITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQHS
180 190 200 210 220 230
310 320 330 340 350 360
pF1KB6 WFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDIIYTQDFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDIIYTQDFT
240 250 260 270 280 290
370 380 390 400 410 420
pF1KB6 VPGQVPEEEASHNGQRRGLPKAVCMNGTEAAQLSTKSRAEGRAPNPARKACSASSKIRRL
::: :.. .. . : :.. .. ... . .. : .:.:
XP_011 VPG--PRRGGQSQWTAPGPPQGRVYERHRGGAAEHQIQGGGPGPQPCPQGLLRQQQDPPA
300 310 320 330 340 350
430
pF1KB6 SACKQQ
XP_011 VGLQAAVRLAACSPCPGAPPGARARPSVFLPVPPALPERWPPCFCADHAPGPPERPAGPG
360 370 380 390 400 410
>>NP_006242 (OMIM: 602739) 5'-AMP-activated protein kina (559 aa)
initn: 541 init1: 243 opt: 599 Z-score: 322.0 bits: 69.0 E(85289): 3.4e-11
Smith-Waterman score: 602; 36.3% identity (65.8% similar) in 284 aa overlap (37-319:16-289)
10 20 30 40 50 60
pF1KB6 QQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEV
: . :.: ::.:..:: :: :..::::
NP_006 MRRLSSWRKMATAEKQKHDGRVK-IGHYILGDTLGVGTFGKVKVG
10 20 30 40
70 80 90 100 110 120
pF1KB6 LDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMY
: . :::::...:.: . . .....::: :. .:: ..:.: .:. . . ..
NP_006 KHELTGHKVAVKILNRQKIRSL-DVVGKIRREIQNLKLFRHPHIIKLYQVISTP--SDIF
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB6 MVMEYCVCGMQEMLDSVPEK-RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLT
::::: : :..: . .. :. ... : :...:..: : . .::.:.:: :.::
NP_006 MVMEYVSGG--ELFDYICKNGRLDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLD
110 120 130 140 150
190 200 210 220 230 240
pF1KB6 TGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTL
. . ::.:.:... . . . ::: ::: . ::. .: ..: .:::::.:: :
NP_006 AHMNAKIADFGLSNMM---SDGEFLRTSCGSPNYAAPEVISG-RLYAGPEVDIWSSGVIL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 YNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQ
: . : ::. :.. ::..: : . : .: . .::: ::. .: :: .:..::.
NP_006 YALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHMLQVDPMKRATIKDIRE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 HSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDIIYTQD
: ::.. : :
NP_006 HEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLSCLYNRNHQDPLAVAY
280 290 300 310 320 330
>>NP_006243 (OMIM: 600497) 5'-AMP-activated protein kina (552 aa)
initn: 542 init1: 221 opt: 574 Z-score: 309.9 bits: 66.8 E(85289): 1.6e-10
Smith-Waterman score: 577; 36.0% identity (64.0% similar) in 292 aa overlap (37-327:5-284)
10 20 30 40 50 60
pF1KB6 QQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEV
: . :.: ::.:..:: :: :..::::
NP_006 MAEKQKHDGRVK-IGHYVLGDTLGVGTFGKVKIG
10 20 30
70 80 90 100 110 120
pF1KB6 LDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMY
. : . :::::...:.: . . ...:.::: :. .:: ..:.: .:. . ..
NP_006 EHQLTGHKVAVKILNRQKIRSL-DVVGKIKREIQNLKLFRHPHIIKLYQVISTPT--DFF
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB6 MVMEYCVCGMQEMLDSVPEK-RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLT
::::: : :..: . .. : .:. : :......: : . .::.:.:: :.::
NP_006 MVMEYVSGG--ELFDYICKHGRVEEMEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLD
100 110 120 130 140
190 200 210 220 230 240
pF1KB6 TGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTL
. . ::.:.:... . . . ::: ::: . ::. .: ..: .::::: :: :
NP_006 AHMNAKIADFGLSNMM---SDGEFLRTSCGSPNYAAPEVISG-RLYAGPEVDIWSCGVIL
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB6 YNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQ
: . : ::. ... ::..: : . :: . .. :: ::. .: :: .:..::.
NP_006 YALLCGTLPFDDEHVPTLFKKIRGGVFYIPEYLNRSVATLLMHMLQVDPLKRATIKDIRE
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB6 HSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADEDEDLFDIEDDIIYTQD
: ::.. : : :: :
NP_006 HEWFKQDLPSYL--FPEDPSYDANVIDDEAVKEVCEKFECTESEVMNSLYSGDPQDQLAV
270 280 290 300 310 320
>>NP_996790 (OMIM: 602739) 5'-AMP-activated protein kina (574 aa)
initn: 541 init1: 243 opt: 559 Z-score: 302.4 bits: 65.5 E(85289): 4.2e-10
Smith-Waterman score: 576; 35.1% identity (62.9% similar) in 299 aa overlap (37-319:16-304)
10 20 30 40 50 60
pF1KB6 QQLGMFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEV
: . :.: ::.:..:: :: :..::::
NP_996 MRRLSSWRKMATAEKQKHDGRVK-IGHYILGDTLGVGTFGKVKVG
10 20 30 40
70 80 90 100 110 120
pF1KB6 LDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMY
: . :::::...:.: . . .....::: :. .:: ..:.: .:. . . ..
NP_996 KHELTGHKVAVKILNRQKIRSL-DVVGKIRREIQNLKLFRHPHIIKLYQVISTP--SDIF
50 60 70 80 90 100
130 140 150 160 170
pF1KB6 MVMEYCVCGMQEMLD---------SVP-------EKRFPVCQAHGYFCQLIDGLEYLHSQ
::::: : :..: .:: :.. ... : :...:..: : .
NP_996 MVMEYVSGG--ELFDYICKNGRKSDVPGVVKTGSTKELDEKESRRLFQQILSGVDYCHRH
110 120 130 140 150
180 190 200 210 220 230
pF1KB6 GIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDT
.::.:.:: :.:: . . ::.:.:... . . . ::: ::: . ::. .:
NP_996 MVVHRDLKPENVLLDAHMNAKIADFGLSNMM---SDGEFLRTSCGSPNYAAPEVISG-RL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 FSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGML
..: .:::::.:: :: . : ::. :.. ::..: : . : .: . .::: ::
NP_996 YAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVISLLKHML
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB6 EYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDLHGADED
. .: :: .:..::.: ::.. : :
NP_996 QVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECSEEEVLS
280 290 300 310 320 330
>>XP_016865114 (OMIM: 602739) PREDICTED: 5'-AMP-activate (533 aa)
initn: 435 init1: 243 opt: 526 Z-score: 286.6 bits: 62.4 E(85289): 3.2e-09
Smith-Waterman score: 526; 35.5% identity (66.5% similar) in 245 aa overlap (76-319:28-263)
50 60 70 80 90 100
pF1KB6 IGKYLMGDLLGEGSYGKVKEVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRL
:::::...:.: . . .....::: :. .
XP_016 MQVKNIRKLPCQIIQSVGKHELTGHKVAVKILNRQKIRSL-DVVGKIRREIQNLKLF
10 20 30 40 50
110 120 130 140 150 160
pF1KB6 RHKNVIQLVDVLYNEEKQKMYMVMEYCVCGMQEMLDSVPEK-RFPVCQAHGYFCQLIDGL
:: ..:.: .:. . . ..::::: : :..: . .. :. ... : :...:.
XP_016 RHPHIIKLYQVISTP--SDIFMVMEYVSGG--ELFDYICKNGRLDEKESRRLFQQILSGV
60 70 80 90 100 110
170 180 190 200 210 220
pF1KB6 EYLHSQGIVHKDIKPGNLLLTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEI
.: : . .::.:.:: :.:: . . ::.:.:... . . . ::: ::: . ::.
XP_016 DYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMM---SDGEFLRTSCGSPNYAAPEV
120 130 140 150 160
230 240 250 260 270 280
pF1KB6 ANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSD
.: ..: .:::::.:: :: . : ::. :.. ::..: : . : .: . .
XP_016 ISG-RLYAGPEVDIWSSGVILYALLCGTLPFDDDHVPTLFKKICDGIFYTPQYLNPSVIS
170 180 190 200 210 220
290 300 310 320 330 340
pF1KB6 LLKGMLEYEPAKRFSIRQIRQHSWFRKKHPPAEAPVPIPPSPDTKDRWRSMTVVPYLEDL
::: ::. .: :: .:..::.: ::.. : :
XP_016 LLKHMLQVDPMKRATIKDIREHEWFKQDLPKYLFPEDPSYSSTMIDDEALKEVCEKFECS
230 240 250 260 270 280
350 360 370 380 390 400
pF1KB6 HGADEDEDLFDIEDDIIYTQDFTVPGQVPEEEASHNGQRRGLPKAVCMNGTEAAQLSTKS
XP_016 EEEVLSCLYNRNHQDPLAVAYHLIIDNRRIMNEAKDFYLATSPPDSFLDDHHLTRPHPER
290 300 310 320 330 340
>>NP_115806 (OMIM: 609235) serine/threonine-protein kina (778 aa)
initn: 463 init1: 252 opt: 527 Z-score: 285.5 bits: 62.8 E(85289): 3.6e-09
Smith-Waterman score: 587; 30.9% identity (59.1% similar) in 421 aa overlap (41-426:26-429)
20 30 40 50 60 70
pF1KB6 MFTEGELMSVGMDTFIHRIDSTEVIYQPRRKRAKLIGKYLMGDLLGEGSYGKVKEVLDSE
..:. .: : . ::.:. : :: .
NP_115 MSSGAKEGGGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCI
10 20 30 40 50
80 90 100 110 120 130
pF1KB6 TLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQKMYMVME
: . :.::....:: . . .:..:: .:. ..: .:..: :: :.:. .:.:.:
NP_115 TGQKVAIKIVNREKLSE--SVLMKVEREIAILKLIEHPHVLKLHDVY--ENKKYLYLVLE
60 70 80 90 100 110
140 150 160 170 180
pF1KB6 YCVCGMQEMLDSVPEK-RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLLLTTGGT
. : :..: . .: :. .:. .: :....:.. :: .: :.:.:: :::: ..
NP_115 HVSGG--ELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNN
120 130 140 150 160
190 200 210 220 230 240
pF1KB6 LKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGVTLYNIT
..:.:.:.: .:. ..:. .:: ::: . ::. .: . ..: ..:.:: :: :. .
NP_115 IRIADFGMA-SLQ--VGDSLLETSCGSPHYACPEVIKG-EKYDGRRADMWSCGVILFALL
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 TGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQIRQHSWF
.: ::. ::. .:.:.. .: . .: : ..::.::.: :: ::.:..::..: :.
NP_115 VGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWY
230 240 250 260 270 280
310 320 330 340 350
pF1KB6 RK-KHPPAEAPVPIP---------PS-----PDTKDRWRSMTVVPYLEDLH----GADED
:: : : : :: ::. . :. : :: . .:.
NP_115 LGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEEN
290 300 310 320 330 340
360 370 380 390
pF1KB6 ED------LFD-------IED-DIIYTQDFTVPGQ-VPEEEASHNGQRRGLPKAVCMNGT
.. :.: :: :. .: : . : :..:.:: :. :.
NP_115 QEKMIYYLLLDRKERYPSCEDQDLPPRNDVDPPRKRVDSPMLSRHGKRR--PERKSME--
350 360 370 380 390 400
400 410 420 430
pF1KB6 EAAQLSTKSRAEGRAPNPARKACSASSKIRRLSACKQQ
:: . . : .: :.:.: ... .:
NP_115 ---VLSITDAGGGGSPVPTRRALEMAQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPE
410 420 430 440 450
NP_115 PGAGDEARGGGSPTSKTQTLPSRGPRGGGAGEQPPPPSARSTPLPGPPGSPRSSGGTPLH
460 470 480 490 500 510
>>NP_001269147 (OMIM: 609236) serine/threonine-protein k (614 aa)
initn: 449 init1: 248 opt: 522 Z-score: 284.1 bits: 62.2 E(85289): 4.4e-09
Smith-Waterman score: 550; 30.4% identity (62.1% similar) in 359 aa overlap (95-426:3-349)
70 80 90 100 110 120
pF1KB6 EVLDSETLCRRAVKILKKKKLRRIPNGEANVKKEIQLLRRLRHKNVIQLVDVLYNEEKQK
:..:: .:. ..: .:..: :: :.:.
NP_001 MKVEREIAILKLIEHPHVLKLHDVY--ENKKY
10 20 30
130 140 150 160 170 180
pF1KB6 MYMVMEYCVCGMQEMLDSVPEK-RFPVCQAHGYFCQLIDGLEYLHSQGIVHKDIKPGNLL
.:.:.:. : :..: . .: :. .:. .: :.:..:.. ::..: :.:.:: :::
NP_001 LYLVLEHVSGG--ELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLL
40 50 60 70 80
190 200 210 220 230 240
pF1KB6 LTTGGTLKISDLGVAEALHPFAADDTCRTSQGSPAFQPPEIANGLDTFSGFKVDIWSAGV
: ....:.:.:.: .:. ..:. .:: ::: . ::. : . ..: :.:.:: ::
NP_001 LDEKNNIRIADFGMA-SLQ--VGDSLLETSCGSPHYACPEVIRG-EKYDGRKADVWSCGV
90 100 110 120 130 140
250 260 270 280 290 300
pF1KB6 TLYNITTGLYPFEGDNIYKLFENIGKGSYAIPGDCGPPLSDLLKGMLEYEPAKRFSIRQI
:. . .: ::. ::. .:.:.. .: . .: : ..::.::.: . :.:.....:
NP_001 ILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFIPPDCQSLLRGMIEVDAARRLTLEHI
150 160 170 180 190 200
310 320 330 340
pF1KB6 RQHSWF--RKKHPPAEAPVP-------IPP----SPDTKDRWRSMTVV----PYLEDLHG
..: :. :..: : :.: .: .::. : .:. :.:: .
NP_001 QKHIWYIGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLS
210 220 230 240 250 260
350 360 370 380 390
pF1KB6 ADEDED------LFDIEDDIIYTQDFTVPGQVPEEEASHNGQRRGLPKAVCMNGT---EA
.:... :.: .. .: .: :..: . .: : . .: :
NP_001 EEENQEKMIYFLLLDRKERYPSQEDEDLP---PRNEIDPPRKRVDSP-MLNRHGKRRPER
270 280 290 300 310 320
400 410 420 430
pF1KB6 AQLSTKSRAEGRAPNPARKACSASSKIRRLSACKQQ
.. . : ..: .: :::.: ... .:
NP_001 KSMEVLSVTDGGSPVPARRAIEMAQHGQRSRSISGASSGLSTSPLSSPRVTPHPSPRGSP
330 340 350 360 370 380
433 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 09:09:41 2016 done: Sat Nov 5 09:09:42 2016
Total Scan time: 7.820 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]