Result of FASTA (omim) for
pF1KB6596
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6596, 407 aa
1>>>pF1KB6596 407 - 407 aa - 407 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4107+/-0.000467; mu= 16.5436+/- 0.029
mean_var=103.5565+/-26.872, 0's: 0 Z-trim(110.5): 715 B-trim: 1902 in 2/52
Lambda= 0.126033
statistics sampled from 18076 (18920) to 18076 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.573), E-opt: 0.2 (0.222), width: 16
Scan time: 7.950
The best scores are: opt bits E(85289)
NP_001049 (OMIM: 162323) substance-P receptor isof ( 407) 2726 507.1 3.2e-143
NP_056542 (OMIM: 162323) substance-P receptor isof ( 311) 2100 393.1 4.9e-109
NP_001050 (OMIM: 162332,614840) neuromedin-K recep ( 465) 1621 306.2 1.1e-82
NP_001048 (OMIM: 162321) substance-K receptor [Hom ( 398) 1294 246.7 7.5e-65
NP_057624 (OMIM: 605569) probable G-protein couple ( 423) 646 128.9 2.3e-29
XP_005263090 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 586 117.9 4.1e-26
XP_005263091 (OMIM: 162642) PREDICTED: neuropeptid ( 381) 586 117.9 4.1e-26
NP_000901 (OMIM: 162642) neuropeptide Y receptor t ( 381) 586 117.9 4.1e-26
NP_004239 (OMIM: 600895) prolactin-releasing pepti ( 370) 549 111.2 4.3e-24
NP_001305426 (OMIM: 165196) kappa-type opioid rece ( 409) 487 100.0 1.1e-20
NP_000903 (OMIM: 165196) kappa-type opioid recepto ( 380) 486 99.8 1.2e-20
NP_000902 (OMIM: 165195) delta-type opioid recepto ( 372) 482 99.0 2e-20
NP_000900 (OMIM: 162641) neuropeptide Y receptor t ( 384) 480 98.7 2.6e-20
XP_011530312 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 480 98.7 2.6e-20
XP_005263088 (OMIM: 162641) PREDICTED: neuropeptid ( 384) 480 98.7 2.6e-20
NP_658986 (OMIM: 244200,607123) prokineticin recep ( 384) 478 98.3 3.4e-20
XP_016883135 (OMIM: 244200,607123) PREDICTED: prok ( 384) 478 98.3 3.4e-20
XP_011527461 (OMIM: 244200,607123) PREDICTED: prok ( 348) 472 97.2 6.8e-20
NP_620414 (OMIM: 607122) prokineticin receptor 1 [ ( 393) 469 96.7 1.1e-19
NP_001138758 (OMIM: 600018) mu-type opioid recepto ( 420) 466 96.2 1.6e-19
NP_001041 (OMIM: 182452) somatostatin receptor typ ( 369) 464 95.7 1.9e-19
NP_001138757 (OMIM: 600018) mu-type opioid recepto ( 389) 464 95.8 2e-19
NP_001008504 (OMIM: 600018) mu-type opioid recepto ( 392) 464 95.8 2e-19
NP_001138755 (OMIM: 600018) mu-type opioid recepto ( 397) 464 95.8 2e-19
NP_000905 (OMIM: 600018) mu-type opioid receptor i ( 400) 464 95.8 2e-19
NP_001138756 (OMIM: 600018) mu-type opioid recepto ( 403) 464 95.8 2e-19
NP_001138754 (OMIM: 600018) mu-type opioid recepto ( 406) 464 95.8 2.1e-19
NP_001272452 (OMIM: 600018) mu-type opioid recepto ( 414) 464 95.8 2.1e-19
NP_001008503 (OMIM: 600018) mu-type opioid recepto ( 418) 464 95.8 2.1e-19
NP_001008505 (OMIM: 600018) mu-type opioid recepto ( 446) 464 95.8 2.2e-19
NP_001272453 (OMIM: 600018) mu-type opioid recepto ( 493) 464 95.9 2.3e-19
NP_001138751 (OMIM: 600018) mu-type opioid recepto ( 493) 464 95.9 2.3e-19
NP_001471 (OMIM: 600377) galanin receptor type 1 [ ( 349) 449 93.0 1.2e-18
NP_001186948 (OMIM: 602548) nociceptin receptor is ( 370) 447 92.7 1.6e-18
NP_000904 (OMIM: 602548) nociceptin receptor isofo ( 370) 447 92.7 1.6e-18
XP_016883343 (OMIM: 602548) PREDICTED: nociceptin ( 370) 447 92.7 1.6e-18
NP_872588 (OMIM: 602548) nociceptin receptor isofo ( 370) 447 92.7 1.6e-18
XP_016883342 (OMIM: 602548) PREDICTED: nociceptin ( 388) 447 92.7 1.7e-18
XP_011527130 (OMIM: 602548) PREDICTED: nociceptin ( 388) 447 92.7 1.7e-18
XP_016883341 (OMIM: 602548) PREDICTED: nociceptin ( 388) 447 92.7 1.7e-18
NP_002502 (OMIM: 162341) neuromedin-B receptor iso ( 390) 447 92.7 1.7e-18
NP_001305782 (OMIM: 602548) nociceptin receptor is ( 399) 447 92.7 1.7e-18
NP_001042 (OMIM: 182453) somatostatin receptor typ ( 418) 444 92.2 2.6e-18
XP_011528651 (OMIM: 182453) PREDICTED: somatostati ( 418) 444 92.2 2.6e-18
XP_006724374 (OMIM: 182453) PREDICTED: somatostati ( 418) 444 92.2 2.6e-18
XP_005261778 (OMIM: 182453) PREDICTED: somatostati ( 418) 444 92.2 2.6e-18
XP_016884412 (OMIM: 182453) PREDICTED: somatostati ( 418) 444 92.2 2.6e-18
NP_001265616 (OMIM: 182453) somatostatin receptor ( 418) 444 92.2 2.6e-18
XP_016884413 (OMIM: 182453) PREDICTED: somatostati ( 418) 444 92.2 2.6e-18
NP_005305 (OMIM: 305670) gastrin-releasing peptide ( 384) 436 90.7 6.8e-18
>>NP_001049 (OMIM: 162323) substance-P receptor isoform (407 aa)
initn: 2726 init1: 2726 opt: 2726 Z-score: 2692.3 bits: 507.1 E(85289): 3.2e-143
Smith-Waterman score: 2726; 100.0% identity (100.0% similar) in 407 aa overlap (1-407:1-407)
10 20 30 40 50 60
pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 NPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTIST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTIST
310 320 330 340 350 360
370 380 390 400
pF1KB6 VVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS
370 380 390 400
>>NP_056542 (OMIM: 162323) substance-P receptor isoform (311 aa)
initn: 2100 init1: 2100 opt: 2100 Z-score: 2078.6 bits: 393.1 E(85289): 4.9e-109
Smith-Waterman score: 2100; 100.0% identity (100.0% similar) in 311 aa overlap (1-311:1-311)
10 20 30 40 50 60
pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 YSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVVC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYHEQV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 NPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLETTIST
:::::::::::
NP_056 NPIIYCCLNDR
310
>>NP_001050 (OMIM: 162332,614840) neuromedin-K receptor (465 aa)
initn: 1590 init1: 866 opt: 1621 Z-score: 1605.7 bits: 306.2 E(85289): 1.1e-82
Smith-Waterman score: 1621; 60.1% identity (82.0% similar) in 401 aa overlap (13-404:61-456)
10 20 30
pF1KB6 MDNVLPVDSDLSPNISTNTSEP-----NQFVQPAWQIVLWAA
: : :.: ::::::.:.:.::.
NP_001 GAATGAVETGWLQLLDQAGNLSSSPSALGLPVASPAPSQPWANLTNQFVQPSWRIALWSL
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB6 AYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNE
:: :.:...:.::..:.::::::::::::::::::::::..::::::::.::: ::.:.:
NP_001 AYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSE
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB6 WYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVL
::.: ::.:.:::::.:::::::::::.: ::::::: ::.:::::::::.:: ::.:
NP_001 WYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIWIL
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB6 ALLLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYT
:.:::::: :: :..::.:..:...::: :.. . .::: : .:.: .:::..: .::
NP_001 AFLLAFPQCLYSKTKVMPGRTLCFVQWPEGPKQHF--TYHIIVIILVYCFPLLIMGITYT
220 230 240 250 260
220 230 240 250 260 270
pF1KB6 VVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDL
.::::::..:::::. :.::::..::::::::::.:: ::::::::.::.:.: : .:
NP_001 IVGITLWGGEIPGDTCDKYHEQLKAKRKVVKMMIIVVMTFAICWLPYHIYFILTAIYQQL
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB6 YLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMK
:.::::::: .:::::::::::::::::: ::: :::.::: ::::....:. ::.:
NP_001 NRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWCPFIKVSSYDELELK
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB6 STRYLQT-QGSVYKVSRLETTISTVVGAHEEEPEDGPK---ATPSSLDLTSNCSSRSDSK
.::. . :.:.: :.:.:. ...: .. . . . ::: : . : :: .::
NP_001 TTRFHPNRQSSMYTVTRMES-MTVVFDPNDADTTRSSRKKRATPR--DPSFNGCSRRNSK
390 400 410 420 430 440
400
pF1KB6 TMTESFSFSSNVLS
. . . :: :.
NP_001 SASATSSFISSPYTSVDEYS
450 460
>>NP_001048 (OMIM: 162321) substance-K receptor [Homo sa (398 aa)
initn: 1275 init1: 838 opt: 1294 Z-score: 1285.2 bits: 246.7 E(85289): 7.5e-65
Smith-Waterman score: 1294; 50.7% identity (77.6% similar) in 371 aa overlap (8-372:9-379)
10 20 30 40 50
pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILA
....: . .::. . : .:.::..:::.:: ..:...:.::..:.:::::
NP_001 MGTCDIVTEANISSGPESNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 HKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFAS
:.:::::::::.::::.:. :::::.. ::.:: :: ::.: .: :.:.:::.:.:.:
NP_001 HRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 IYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVV
::::::.: ::::::.::.:::::: .::.:: ::..:: :: :: .:::. . .
NP_001 IYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALASPQCFYSTVTMDQGATK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 CMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRYH-E
:.. ::: . .::. : .::::::: :. ::.:.:.::: .:: .. . .
NP_001 CVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLR
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 QVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSST
...: .: :: :..:: ::::::::.:..:.: .. :.: .:::::::::..:::::::
NP_001 HLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAMSST
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 MYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRL----
::::::::::: ::: ::. ::::::... . ::. : :.:. . ....
NP_001 MYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTKEDKLELTPTTSLSTRVNRCHTKETLFMA
310 320 330 340 350 360
360 370 380 390 400
pF1KB6 -ETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSKTMTESFSFSSNVLS
.:. : ..... .:.::
NP_001 GDTAPSEATSGEAGRPQDGSGLWFGYGLLAPTKTHVEI
370 380 390
>>NP_057624 (OMIM: 605569) probable G-protein coupled re (423 aa)
initn: 601 init1: 317 opt: 646 Z-score: 648.1 bits: 128.9 E(85289): 2.3e-29
Smith-Waterman score: 646; 34.3% identity (67.0% similar) in 297 aa overlap (34-323:73-363)
10 20 30 40 50 60
pF1KB6 VLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRM
: .::. :.: :. :::.: .:. ..::
NP_057 SWNNYTFSDWQNFVGRRRYGAESQNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRM
50 60 70 80 90 100
70 80 90 100 110 120
pF1KB6 RTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSM
...:. :.:::: :. .. .:: ... :.. : .: .:. : .. .: ..
NP_057 HSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSRFAQYCSLHVSALTL
110 120 130 140 150 160
130 140 150 160 170
pF1KB6 TAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGY------YSTTETMPSR
::.: ::...:.:::.::.: : . : :::..: ....:.. .. .: . :
NP_057 TAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATFFSLPHAICQKLFTFKYSEDI-VR
170 180 190 200 210 220
180 190 200 210 220 230
pF1KB6 VVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGD-SSDRY
.:. ..:: : .. : . . .:.:.::::.:. ::. :. :: .. :: ....:
NP_057 SLCLPDFPE-PADLFWKYLDLATFILLYILPLLIISVAYARVAKKLWLCNMIGDVTTEQY
230 240 250 260 270 280
240 250 260 270 280 290
pF1KB6 HEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMS
:.:..::...:: ::.::.:.. . :: .. . . . .:.:. :.:::
NP_057 FALRRKKKKTIKMLMLVVVLFALCWFPLNCYVLL--LSSKVI--RTNNALYFAFHWFAMS
290 300 310 320 330
300 310 320 330 340 350
pF1KB6 STMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQGSVYKVSRLET
:: :::.::: ::. ::. .: . :
NP_057 STCYNPFIYCWLNENFRIELKALLSMCQRPPKPQEDRPPSPVPSFRVAWTEKNDGQRAPL
340 350 360 370 380 390
>>XP_005263090 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 444 init1: 263 opt: 586 Z-score: 589.7 bits: 117.9 E(85289): 4.1e-26
Smith-Waterman score: 586; 30.4% identity (62.6% similar) in 342 aa overlap (10-345:31-366)
10 20 30
pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAY
.: :. . . ..... :.:: ::
XP_005 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEV--QVVL-ILAY
10 20 30 40 50
40 50 60 70 80 90
pF1KB6 TVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWY
:.. .:.:: .:. ... : ::::::.:..::: :. . .. ..::.. .::
XP_005 CSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWK
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB6 YGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLAL
.: :.. . :: .: ..:..:.::. :.. :. ..: . ..: . : ..
XP_005 MGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISA
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 LLAFPQGY---YSTTETMPSR--VVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY
::: : . :: : .:. :.: .:: . ..:: :: . ...: ::: .:..
XP_005 LLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN
.:: . : :: ..:.::.. ..:..::.. :: .::. :::.: : : :.
XP_005 SYTRIWSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDID
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 PDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYE-G
.. : . .. .. .:: ::. ::..: .:. .: .: :::: ..: : .
XP_005 SQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVS
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 LEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSK
. .:. . :...
XP_005 VTFKAKKNLEVRKNSGPNDSFTEATNV
360 370 380
>>XP_005263091 (OMIM: 162642) PREDICTED: neuropeptide Y (381 aa)
initn: 444 init1: 263 opt: 586 Z-score: 589.7 bits: 117.9 E(85289): 4.1e-26
Smith-Waterman score: 586; 30.4% identity (62.6% similar) in 342 aa overlap (10-345:31-366)
10 20 30
pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAY
.: :. . . ..... :.:: ::
XP_005 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEV--QVVL-ILAY
10 20 30 40 50
40 50 60 70 80 90
pF1KB6 TVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWY
:.. .:.:: .:. ... : ::::::.:..::: :. . .. ..::.. .::
XP_005 CSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWK
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB6 YGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLAL
.: :.. . :: .: ..:..:.::. :.. :. ..: . ..: . : ..
XP_005 MGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISA
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 LLAFPQGY---YSTTETMPSR--VVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY
::: : . :: : .:. :.: .:: . ..:: :: . ...: ::: .:..
XP_005 LLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN
.:: . : :: ..:.::.. ..:..::.. :: .::. :::.: : : :.
XP_005 SYTRIWSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDID
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 PDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYE-G
.. : . .. .. .:: ::. ::..: .:. .: .: :::: ..: : .
XP_005 SQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVS
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 LEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSK
. .:. . :...
XP_005 VTFKAKKNLEVRKNSGPNDSFTEATNV
360 370 380
>>NP_000901 (OMIM: 162642) neuropeptide Y receptor type (381 aa)
initn: 444 init1: 263 opt: 586 Z-score: 589.7 bits: 117.9 E(85289): 4.1e-26
Smith-Waterman score: 586; 30.4% identity (62.6% similar) in 342 aa overlap (10-345:31-366)
10 20 30
pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAAAY
.: :. . . ..... :.:: ::
NP_000 MGPIGAEADENQTVEEMKVEQYGPQTTPRGELVPDPEPELIDSTKLIEV--QVVL-ILAY
10 20 30 40 50
40 50 60 70 80 90
pF1KB6 TVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWY
:.. .:.:: .:. ... : ::::::.:..::: :. . .. ..::.. .::
NP_000 CSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWK
60 70 80 90 100 110
100 110 120 130 140 150
pF1KB6 YGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLAL
.: :.. . :: .: ..:..:.::. :.. :. ..: . ..: . : ..
NP_000 MGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISA
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 LLAFPQGY---YSTTETMPSR--VVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGY
::: : . :: : .:. :.: .:: . ..:: :: . ...: ::: .:..
NP_000 LLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 AYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFLLPYIN
.:: . : :: ..:.::.. ..:..::.. :: .::. :::.: : : :.
NP_000 SYTRIWSKLKNHVSPGAANDHYHQR---RQKTTKMLVCVVVVFAVSWLPLHAFQLAVDID
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 PDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYE-G
.. : . .. .. .:: ::. ::..: .:. .: .: :::: ..: : .
NP_000 SQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSEVS
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB6 LEMKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTSNCSSRSDSK
. .:. . :...
NP_000 VTFKAKKNLEVRKNSGPNDSFTEATNV
360 370 380
>>NP_004239 (OMIM: 600895) prolactin-releasing peptide r (370 aa)
initn: 340 init1: 230 opt: 549 Z-score: 553.5 bits: 111.2 E(85289): 4.3e-24
Smith-Waterman score: 549; 32.3% identity (65.3% similar) in 297 aa overlap (22-313:49-343)
10 20 30 40 50
pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIV-LWAAAYTVIVVTSVVGN
: : .: . :. : . :.:.::...:::
NP_004 PPAVTTPANQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGN
20 30 40 50 60 70
60 70 80 90 100
pF1KB6 VVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNE-WYYGLFYCKFHN
... .: .:...:::... :::.... : . . ....:: . . : .: :..
NP_004 CLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVF
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB6 FFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYS
:. ..:..:....:..: :::....:::. :.: . .. .::.:. .::.: . ..
NP_004 FLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHT
140 150 160 170 180 190
170 180 190 200 210 220
pF1KB6 T-TETMPSRV-VCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASE
.: : : .: : . . ...: . .. :.:::::: .:. :.. :
NP_004 YHVELKPHDVRLCEEFWGSQERQ--RQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRNRV
200 210 220 230 240 250
230 240 250 260 270 280
pF1KB6 IPGDSSDRYHEQVSAKRK-VVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQV
.:: .. . :.:. . ...::: .::.::::.:.: :: ..: . :
NP_004 VPGCVTQSQADWDRARRRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLV
260 270 280 290 300 310
290 300 310 320 330 340
pF1KB6 YLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAGDYEGLEMKSTRYLQTQG
: ::::::. :::.:: :.: ::
NP_004 QLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLVAWPRKIAPHGQNMTVSVVI
320 330 340 350 360 370
>>NP_001305426 (OMIM: 165196) kappa-type opioid receptor (409 aa)
initn: 285 init1: 141 opt: 487 Z-score: 492.1 bits: 100.0 E(85289): 1.1e-20
Smith-Waterman score: 487; 26.3% identity (60.7% similar) in 377 aa overlap (8-371:37-399)
10 20 30
pF1KB6 MDNVLPVDSDLSPNISTNTSEPNQFVQPAWQIVLWAA
::. : . :: . ..:: ... .:
NP_001 IFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAH-ISPAIPVII-TA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 AYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNFTYAVH--
.:.:. :...::: .::..:. . .:.:.:: .. :::.:.: .. :.. : .:.
NP_001 VYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVT---TTMPFQSTVYLM
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 NEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQP---RLSATATKVVIC
: : .: ::. . .:.::...: .. :::.:. ::.. : : . ::
NP_001 NSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINIC
130 140 150 160 170 180
160 170 180 190 200
pF1KB6 VIWVLAL---LLAFPQGYYSTTETMPSRVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPL
::.:. . :. : .. : . . . : ...:. . .. ..::: .. . .:.
NP_001 -IWLLSSSVGISAIVLGGTKVREDV-DVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPV
190 200 210 220 230
210 220 230 240 250 260
pF1KB6 LVIGYAYTVVGITLWASEIPGDSSDRYHEQVSAKRKVVKMMIVVVCTFAICWLPFHIFFL
:.: ::.. . : . .. . : .. .. :.......::: .:..:: :.:::.:
NP_001 LIIIVCYTLMILRLKSVRLLSGSREKDRNL----RRITRLVLVVVAVFVVCWTPIHIFIL
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB6 LPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCCPFISAG
. .. . ... :. : :..... :::.: :.. :. :. : : :.
NP_001 VEALGSTSHSTAALSSYYFCIA-LGYTNSSLNPILYAFLDENFKRCFRD-F-CFPLKMRM
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB6 DYEGLE-----MKSTRYLQTQGSVYKVSRLETTISTVVGAHEEEPEDGPKATPSSLDLTS
. .. ... ::. .. : : . .:. .. .:: .:
NP_001 ERQSTSRVRNTVQDPAYLRDIDGMNKPVXLVVEMSSYSSSGREEFNDLGLTQITTAV
360 370 380 390 400
390 400
pF1KB6 NCSSRSDSKTMTESFSFSSNVLS
407 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sun Nov 6 07:04:38 2016 done: Sun Nov 6 07:04:39 2016
Total Scan time: 7.950 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]