Result of FASTA (omim) for
pF1KB6528
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6528, 388 aa
1>>>pF1KB6528 388 - 388 aa - 388 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3559+/-0.000475; mu= 16.3181+/- 0.029
mean_var=64.0740+/-12.567, 0's: 0 Z-trim(108.7): 61 B-trim: 0 in 0/49
Lambda= 0.160226
statistics sampled from 16712 (16773) to 16712 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.555), E-opt: 0.2 (0.197), width: 16
Scan time: 6.330
The best scores are: opt bits E(85289)
NP_002551 (OMIM: 600846) P2X purinoceptor 4 isofor ( 388) 2612 613.0 3.8e-175
NP_001243725 (OMIM: 600846) P2X purinoceptor 4 iso ( 404) 2324 546.4 4.3e-155
NP_001248327 (OMIM: 600846) P2X purinoceptor 4 iso ( 341) 2256 530.7 2e-150
NP_001248326 (OMIM: 600846) P2X purinoceptor 4 iso ( 361) 1455 345.5 1.1e-94
XP_011536718 (OMIM: 600846) PREDICTED: P2X purinoc ( 258) 1444 342.9 5e-94
NP_002549 (OMIM: 600845,609821) P2X purinoceptor 1 ( 399) 1431 340.0 5.8e-93
XP_011522201 (OMIM: 600845,609821) PREDICTED: P2X ( 411) 1249 298.0 2.8e-80
NP_002552 (OMIM: 602836) P2X purinoceptor 5 isofor ( 422) 1196 285.7 1.4e-76
NP_001191448 (OMIM: 602836) P2X purinoceptor 5 iso ( 421) 1179 281.8 2.1e-75
NP_777362 (OMIM: 600844,608224) P2X purinoceptor 2 ( 404) 1176 281.1 3.3e-75
NP_733782 (OMIM: 600844,608224) P2X purinoceptor 2 ( 471) 1175 280.9 4.4e-75
XP_016874524 (OMIM: 600844,608224) PREDICTED: P2X ( 462) 1173 280.4 5.9e-75
NP_002553 (OMIM: 602566) P2X purinoceptor 7 [Homo ( 595) 1137 272.1 2.4e-72
XP_005266213 (OMIM: 600844,608224) PREDICTED: P2X ( 430) 1111 266.1 1.1e-70
XP_005266212 (OMIM: 600844,608224) PREDICTED: P2X ( 488) 1111 266.1 1.3e-70
NP_733783 (OMIM: 600844,608224) P2X purinoceptor 2 ( 497) 1111 266.1 1.3e-70
XP_011522199 (OMIM: 600845,609821) PREDICTED: P2X ( 419) 1096 262.6 1.2e-69
NP_001269094 (OMIM: 600844,608224) P2X purinocepto ( 349) 1035 248.5 1.9e-65
NP_002550 (OMIM: 600843) P2X purinoceptor 3 [Homo ( 397) 1002 240.9 4.1e-63
XP_011543371 (OMIM: 600843) PREDICTED: P2X purinoc ( 397) 1002 240.9 4.1e-63
XP_011543372 (OMIM: 600843) PREDICTED: P2X purinoc ( 397) 1002 240.9 4.1e-63
XP_011543373 (OMIM: 600843) PREDICTED: P2X purinoc ( 395) 990 238.1 2.8e-62
XP_011543374 (OMIM: 600843) PREDICTED: P2X purinoc ( 323) 987 237.3 3.8e-62
XP_011536721 (OMIM: 602566) PREDICTED: P2X purinoc ( 491) 950 228.9 2.1e-59
XP_011522198 (OMIM: 600845,609821) PREDICTED: P2X ( 431) 914 220.5 5.9e-57
NP_005437 (OMIM: 608077) P2X purinoceptor 6 isofor ( 441) 910 219.6 1.1e-56
XP_016884557 (OMIM: 608077) PREDICTED: P2X purinoc ( 393) 909 219.4 1.2e-56
XP_011528800 (OMIM: 608077) PREDICTED: P2X purinoc ( 539) 909 219.4 1.6e-56
XP_005266211 (OMIM: 600844,608224) PREDICTED: P2X ( 512) 907 218.9 2.1e-56
NP_777361 (OMIM: 600844,608224) P2X purinoceptor 2 ( 379) 881 212.9 1e-54
NP_057402 (OMIM: 600844,608224) P2X purinoceptor 2 ( 447) 881 212.9 1.2e-54
XP_011522200 (OMIM: 600845,609821) PREDICTED: P2X ( 414) 837 202.7 1.3e-51
XP_016874853 (OMIM: 602566) PREDICTED: P2X purinoc ( 475) 833 201.8 2.8e-51
XP_016874854 (OMIM: 602566) PREDICTED: P2X purinoc ( 475) 833 201.8 2.8e-51
NP_036358 (OMIM: 600844,608224) P2X purinoceptor 2 ( 399) 829 200.9 4.5e-51
NP_001153026 (OMIM: 608077) P2X purinoceptor 6 iso ( 415) 819 198.6 2.3e-50
XP_011528802 (OMIM: 608077) PREDICTED: P2X purinoc ( 513) 818 198.4 3.3e-50
XP_011533088 (OMIM: 600844,608224) PREDICTED: P2X ( 473) 817 198.1 3.6e-50
XP_011528804 (OMIM: 608077) PREDICTED: P2X purinoc ( 324) 802 194.6 2.9e-49
XP_016884555 (OMIM: 608077) PREDICTED: P2X purinoc ( 425) 802 194.6 3.6e-49
XP_005261876 (OMIM: 608077) PREDICTED: P2X purinoc ( 473) 802 194.7 4e-49
NP_001191449 (OMIM: 602836) P2X purinoceptor 5 iso ( 398) 790 191.8 2.3e-48
NP_778255 (OMIM: 602836) P2X purinoceptor 5 isofor ( 397) 773 187.9 3.5e-47
XP_011543375 (OMIM: 600843) PREDICTED: P2X purinoc ( 233) 733 178.6 1.4e-44
XP_006721592 (OMIM: 600845,609821) PREDICTED: P2X ( 382) 711 173.6 7.1e-43
XP_016884558 (OMIM: 608077) PREDICTED: P2X purinoc ( 391) 588 145.1 2.6e-34
XP_016884556 (OMIM: 608077) PREDICTED: P2X purinoc ( 417) 588 145.2 2.8e-34
XP_011528801 (OMIM: 608077) PREDICTED: P2X purinoc ( 515) 587 145.0 3.9e-34
XP_011522202 (OMIM: 600845,609821) PREDICTED: P2X ( 316) 519 129.2 1.4e-29
XP_016884565 (OMIM: 608077) PREDICTED: P2X purinoc ( 290) 516 128.4 2.1e-29
>>NP_002551 (OMIM: 600846) P2X purinoceptor 4 isoform 2 (388 aa)
initn: 2612 init1: 2612 opt: 2612 Z-score: 3265.5 bits: 613.0 E(85289): 3.8e-175
Smith-Waterman score: 2612; 100.0% identity (100.0% similar) in 388 aa overlap (1-388:1-388)
10 20 30 40 50 60
pF1KB6 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
310 320 330 340 350 360
370 380
pF1KB6 MKKRLYYREKKYKYVEDYEQGLASELDQ
::::::::::::::::::::::::::::
NP_002 MKKRLYYREKKYKYVEDYEQGLASELDQ
370 380
>>NP_001243725 (OMIM: 600846) P2X purinoceptor 4 isoform (404 aa)
initn: 2598 init1: 2324 opt: 2324 Z-score: 2905.5 bits: 546.4 E(85289): 4.3e-155
Smith-Waterman score: 2570; 96.0% identity (96.0% similar) in 404 aa overlap (1-388:1-404)
10 20 30 40
pF1KB6 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIG---------------
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGCYHPHLAEVEMESPR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 -WVFVWEKGYQETDSVVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTN
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RWVFVWEKGYQETDSVVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTN
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB6 VILTMNQTQGLCPEIPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VILTMNQTQGLCPEIPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAW
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB6 CPVEDDTHVPQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CPVEDDTHVPQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTD
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB6 PFCPIFRLGKIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFCPIFRLGKIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDV
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB6 EHNVSPGYNFRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHNVSPGYNFRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLA
310 320 330 340 350 360
350 360 370 380
pF1KB6 LLGMATVLCDIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ
::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGMATVLCDIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ
370 380 390 400
>>NP_001248327 (OMIM: 600846) P2X purinoceptor 4 isoform (341 aa)
initn: 2256 init1: 2256 opt: 2256 Z-score: 2821.6 bits: 530.7 E(85289): 2e-150
Smith-Waterman score: 2256; 99.7% identity (99.7% similar) in 334 aa overlap (1-334:1-334)
10 20 30 40 50 60
pF1KB6 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
:::::::::::::::::::::::::::::::: :
NP_001 RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDITPEKFLESD
310 320 330 340
370 380
pF1KB6 MKKRLYYREKKYKYVEDYEQGLASELDQ
>>NP_001248326 (OMIM: 600846) P2X purinoceptor 4 isoform (361 aa)
initn: 1443 init1: 1443 opt: 1455 Z-score: 1820.6 bits: 345.5 E(85289): 1.1e-94
Smith-Waterman score: 2345; 93.0% identity (93.0% similar) in 388 aa overlap (1-388:1-361)
10 20 30 40 50 60
pF1KB6 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLK
:::::::::::::::::::::::::::: :::::
NP_001 DATTVCKSDASCTAGSAGTHSNGVSTGR---------------------------PAFLK
130 140 150
190 200 210 220 230 240
pF1KB6 AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB6 HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB6 RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
280 290 300 310 320 330
370 380
pF1KB6 MKKRLYYREKKYKYVEDYEQGLASELDQ
::::::::::::::::::::::::::::
NP_001 MKKRLYYREKKYKYVEDYEQGLASELDQ
340 350 360
>>XP_011536718 (OMIM: 600846) PREDICTED: P2X purinocepto (258 aa)
initn: 1442 init1: 1442 opt: 1444 Z-score: 1809.1 bits: 342.9 E(85289): 5e-94
Smith-Waterman score: 1460; 66.5% identity (66.5% similar) in 388 aa overlap (1-388:1-258)
10 20 30 40 50 60
pF1KB6 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIG---------------
10 20 30 40
70 80 90 100 110 120
pF1KB6 VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
XP_011 ------------------------------------------------------------
130 140 150 160 170 180
pF1KB6 DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLK
:::::
XP_011 -------------------------------------------------------PAFLK
50
190 200 210 220 230 240
pF1KB6 AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
60 70 80 90 100 110
250 260 270 280 290 300
pF1KB6 HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
120 130 140 150 160 170
310 320 330 340 350 360
pF1KB6 RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
180 190 200 210 220 230
370 380
pF1KB6 MKKRLYYREKKYKYVEDYEQGLASELDQ
::::::::::::::::::::::::::::
XP_011 MKKRLYYREKKYKYVEDYEQGLASELDQ
240 250
>>NP_002549 (OMIM: 600845,609821) P2X purinoceptor 1 [Ho (399 aa)
initn: 1394 init1: 579 opt: 1431 Z-score: 1789.9 bits: 340.0 E(85289): 5.8e-93
Smith-Waterman score: 1431; 51.8% identity (82.4% similar) in 380 aa overlap (8-387:9-382)
10 20 30 40 50
pF1KB6 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDS
::::::::::::.::.:..:::.. : .::..:.:::::::..::::: ...
NP_002 MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 VVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEI
..:::..:.::.:::. :: ..:::::::.::: .::. :::: :.: .:::: : :
NP_002 LISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEH
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 PDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFL
:.. .:: :..:: :.: ...:. ::.::::: .:::::. .::::: : .:.::.:
NP_002 PEGG-ICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALL
130 140 150 160 170
180 190 200 210 220 230
pF1KB6 KAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENA
. ::::::..::.: .:.:. ..::.. .......:.:.. :.::.:.:: .:...
NP_002 REAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQES
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 GHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKY
:..:. .: .::..:: ..: :.:: . : : : :. : :.:.:::.:::::..
NP_002 GQNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYE---EKNLSPGFNFRFARH
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 YRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLY
. . :.. : :.:..::::::.: :::::::::::: .::::....:.::::::...:.
NP_002 FVE-NGTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLH
300 310 320 330 340 350
360 370 380
pF1KB6 CMKKRLYYREKKYKYVEDYEQGLASELDQ
. :: ::..::.::.::. : :.: :
NP_002 ILPKRHYYKQKKFKYAEDMGPG-AAERDLAATSSTLGLQENMRTS
360 370 380 390
>>XP_011522201 (OMIM: 600845,609821) PREDICTED: P2X puri (411 aa)
initn: 1212 init1: 579 opt: 1249 Z-score: 1562.4 bits: 298.0 E(85289): 2.8e-80
Smith-Waterman score: 1249; 50.0% identity (81.0% similar) in 342 aa overlap (46-387:59-394)
20 30 40 50 60 70
pF1KB6 DTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSVVSSVTTKVKGVAVTN
:::..::::: .....:::..:.::.:::.
XP_011 GSAESEAAWDAPAVWLSREPRQAWQRLAHLWVFLYEKGYQTSSGLISSVSVKLKGLAVTQ
30 40 50 60 70 80
80 90 100 110 120 130
pF1KB6 TSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIPDATTVCKSDASCTAG
:: ..:::::::.::: .::. :::: :.: .:::: : : :.. .:: :..:: :
XP_011 LPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEHPEGG-ICKEDSGCTPG
90 100 110 120 130 140
140 150 160 170 180 190
pF1KB6 SAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLKAAENFTLLVKNNIWY
.: ...:. ::.::::: .:::::. .::::: : .:.::.:. ::::::..::.: .
XP_011 KAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLREAENFTLFIKNSISF
150 160 170 180 190 200
200 210 220 230 240 250
pF1KB6 PKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAGHSFQDMAVEGGIMGI
:.:. ..::.. .......:.:.. :.::.:.:: .:...:..:. .: .::..::
XP_011 PRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESGQNFSTLAEKGGVVGI
210 220 230 240 250 260
260 270 280 290 300 310
pF1KB6 QVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYYRDLAGNEQRTLIKAY
..: :.:: . : : : :. : :.:.:::.:::::... . :.. : :.:..
XP_011 TIDWHCDLDWHVRHCRPIYEFHGLYE---EKNLSPGFNFRFARHFVE-NGTNYRHLFKVF
270 280 290 300 310 320
320 330 340 350 360 370
pF1KB6 GIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYCMKKRLYYREKKYKYV
::::::.: :::::::::::: .::::....:.::::::...:. . :: ::..::.::.
XP_011 GIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKRHYYKQKKFKYA
330 340 350 360 370 380
380
pF1KB6 EDYEQGLASELDQ
::. : :.: :
XP_011 EDMGPG-AAERDLAATSSTLGLQENMRTS
390 400 410
>>NP_002552 (OMIM: 602836) P2X purinoceptor 5 isoform A (422 aa)
initn: 1105 init1: 407 opt: 1196 Z-score: 1496.0 bits: 285.7 E(85289): 1.4e-76
Smith-Waterman score: 1246; 50.3% identity (74.0% similar) in 392 aa overlap (2-388:4-367)
10 20 30 40 50
pF1KB6 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETD
::: .: ::.: : . :. ...::::. : .: ::::.. :::. .::::..:
NP_002 MGQAGC-KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVD
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 -SVVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCP
:. :.: ::::::: :::: :: ::::::::::::: :: .::.::.:.: :: :..:
NP_002 TSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 E---IPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVK-TCEVAAWCPVEDDTHV
: :::. .:..:..: :: : : .:::.::::. .. .. :::. ::::.: ...
NP_002 ENEGIPDG--ACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSR-
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 PQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLG
:. ::: ::.::...::.: .::::::: :.. ..:::: . : . .:::::::
NP_002 PEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPK-NHYCPIFRLG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 KIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYN
.... :: .:::.:.:::..::...:.:.::.::: : :.::: :::.. . ..:: :::
NP_002 SVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNK-LSKSVSSGYN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 FRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLC
::::.:::: :: : :::.::::::::..: :: : : .:
NP_002 FRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK-GAF---------------------FC
300 310 320 330
360 370 380
pF1KB6 DIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ
:....: .::: .::.:::. :. :.. :.
NP_002 DLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQEL
340 350 360 370 380 390
NP_002 QEPPEAKRGSSSQKGNGSVCPQLLEPHRST
400 410 420
>>NP_001191448 (OMIM: 602836) P2X purinoceptor 5 isoform (421 aa)
initn: 992 init1: 292 opt: 1179 Z-score: 1474.8 bits: 281.8 E(85289): 2.1e-75
Smith-Waterman score: 1229; 50.0% identity (74.0% similar) in 392 aa overlap (2-388:4-366)
10 20 30 40 50
pF1KB6 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETD
::: .: ::.: : . :. ...::::. : .: ::::.. :::. .::::..:
NP_001 MGQAGC-KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVD
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 -SVVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCP
:. :.: ::::::: :::: :: ::::::::::::: :: .::.::.:.: :: :..:
NP_001 TSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 E---IPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVK-TCEVAAWCPVEDDTHV
: :::. .:..:..: :: : : .:::.::::. .. .. :::. ::::.: ...
NP_001 ENEGIPDG--ACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSR-
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 PQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLG
:. ::: ::.::...::.: .::::::. :.. ..:::: . : . .:::::::
NP_001 PEEPFLKEAEDFTIFIKNHIRFPKFNFSN-NVMDVKDRSFLKSCHFGPK-NHYCPIFRLG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 KIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYN
.... :: .:::.:.:::..::...:.:.::.::: : :.::: :::.. . ..:: :::
NP_001 SVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNK-LSKSVSSGYN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 FRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLC
::::.:::: :: : :::.::::::::..: :: : : .:
NP_001 FRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK-GAF---------------------FC
300 310 320 330
360 370 380
pF1KB6 DIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ
:....: .::: .::.:::. :. :.. :.
NP_001 DLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQEL
340 350 360 370 380 390
NP_001 QEPPEAKRGSSSQKGNGSVCPQLLEPHRST
400 410 420
>>NP_777362 (OMIM: 600844,608224) P2X purinoceptor 2 iso (404 aa)
initn: 793 init1: 330 opt: 1176 Z-score: 1471.3 bits: 281.1 E(85289): 3.3e-75
Smith-Waterman score: 1176; 49.5% identity (73.9% similar) in 380 aa overlap (3-377:20-383)
10 20 30 40
pF1KB6 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYV
:: .:: ..:.::.....:.:..:.. :::::::: :
NP_777 MAAAQPKYPAGATARRLARGCWSAL----WDYETPKVIVVRNRRLGVLYRAVQLLILLYF
10 20 30 40 50
50 60 70 80 90 100
pF1KB6 IGWVFVWEKGYQETDS-VVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLF-V
. .::. .:.:::... ::. :::::..... ..::: .:: : : .:.: .
NP_777 VWYVFIVQKSYQESETGPESSIITKVKGITTSE-----HKVWDVEEYVKPP-EGGSVFSI
60 70 80 90 100 110
110 120 130 140 150
pF1KB6 MTNVILTMNQTQGLCPE-IPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAF-NGSVKTC
.: : : .:::: ::: : ...: :::.:.:: .::. ::::: . .: :::
NP_777 ITRVEATHSQTQGTCPESIRVHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTC
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 EVAAWCPVEDDTHVPQPAFLKA-AENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCI
:: .:::::: . : : :: . : :::.:.::.: ::::.::: :: . : ::: :
NP_777 EVFGWCPVEDGASVSQ--FLGTMAPNFTILIKNSIHYPKFHFSKGNI-ADRTDGYLKRCT
180 190 200 210 220
220 230 240 250 260 270
pF1KB6 YDAKTDPFCPIFRLGKIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRR
. .: .::::.:: :::.::.:: ..: .::..:. .::::.:: :: : :.:::::
NP_777 FHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRR
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB6 LDTRDVEHNVSPGYNFRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMIN
:: . : .: ::::::::::. . :. ::::::::::.:.:: :.::::..:::.::
NP_777 LDPKHVP--ASSGYNFRFAKYYK-INGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIIN
290 300 310 320 330 340
340 350 360 370 380
pF1KB6 IGSGLALLGMATVLCDIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ
....:. .:... ::: :.: :.: : .::. . :
NP_777 LATALTSVGVGSFLCDWILLTFMNKNKVYSHKKFDKMVDTPASEPAQASTPTDPKGLAQL
350 360 370 380 390 400
388 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:15:21 2016 done: Fri Nov 4 23:15:23 2016
Total Scan time: 6.330 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]