Result of FASTA (omim) for
pF1KB6525
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6525, 365 aa
1>>>pF1KB6525 365 - 365 aa - 365 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4050+/-0.000286; mu= 16.4760+/- 0.018
mean_var=75.8040+/-15.443, 0's: 0 Z-trim(118.8): 156 B-trim: 208 in 1/59
Lambda= 0.147309
statistics sampled from 31881 (32044) to 31881 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.745), E-opt: 0.2 (0.376), width: 16
Scan time: 9.360
The best scores are: opt bits E(85289)
NP_004098 (OMIM: 601437) IgG receptor FcRn large s ( 365) 2530 546.7 3.1e-155
NP_001129491 (OMIM: 601437) IgG receptor FcRn larg ( 365) 2530 546.7 3.1e-155
XP_005258714 (OMIM: 601437) PREDICTED: IgG recepto ( 225) 1544 337.0 2.5e-92
XP_011524929 (OMIM: 601437) PREDICTED: IgG recepto ( 273) 1113 245.4 1.1e-64
NP_001522 (OMIM: 600764) major histocompatibility ( 341) 537 123.1 9.4e-28
NP_005505 (OMIM: 106300,142830,608579) major histo ( 362) 516 118.6 2.2e-26
NP_001229971 (OMIM: 142840,177900,609423) HLA clas ( 366) 511 117.6 4.6e-26
XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 507 116.7 7.8e-26
NP_002108 (OMIM: 142840,177900,609423) HLA class I ( 366) 506 116.5 9.5e-26
NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 499 115.0 2.6e-25
XP_016866302 (OMIM: 143110) PREDICTED: HLA class I ( 388) 499 115.1 2.8e-25
XP_016866301 (OMIM: 143110) PREDICTED: HLA class I ( 420) 499 115.1 3e-25
XP_016866300 (OMIM: 143110) PREDICTED: HLA class I ( 431) 499 115.1 3e-25
XP_016866299 (OMIM: 143110) PREDICTED: HLA class I ( 435) 499 115.1 3.1e-25
NP_001091949 (OMIM: 143110) HLA class I histocompa ( 442) 499 115.1 3.1e-25
NP_001287678 (OMIM: 104300,176100,176200,235200,61 ( 337) 492 113.5 7e-25
NP_000401 (OMIM: 104300,176100,176200,235200,61263 ( 348) 492 113.5 7.2e-25
XP_011512845 (OMIM: 104300,176100,176200,235200,61 ( 348) 492 113.5 7.2e-25
NP_005507 (OMIM: 143010) HLA class I histocompatib ( 358) 455 105.7 1.7e-22
XP_016866298 (OMIM: 143010) PREDICTED: HLA class I ( 359) 455 105.7 1.7e-22
XP_016866296 (OMIM: 143010) PREDICTED: HLA class I ( 399) 455 105.7 1.9e-22
XP_016866297 (OMIM: 143010) PREDICTED: HLA class I ( 399) 455 105.7 1.9e-22
NP_001176 (OMIM: 194460) zinc-alpha-2-glycoprotein ( 298) 453 105.2 2e-22
NP_620578 (OMIM: 104300,176100,176200,235200,61263 ( 325) 447 104.0 5.2e-22
NP_001229687 (OMIM: 142800,608579) HLA class I his ( 365) 446 103.8 6.5e-22
XP_011512859 (OMIM: 106300,142830,608579) PREDICTE ( 323) 440 102.5 1.4e-21
NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 432 100.8 5.2e-21
NP_002118 (OMIM: 142871,600807) HLA class I histoc ( 338) 415 97.2 5.9e-20
XP_016866305 (OMIM: 142871,600807) PREDICTED: HLA ( 343) 415 97.2 6e-20
XP_016885777 (OMIM: 142800,608579) PREDICTED: HLA ( 362) 407 95.5 2e-19
XP_005275388 (OMIM: 142800,608579) PREDICTED: HLA ( 391) 407 95.5 2.2e-19
NP_620576 (OMIM: 104300,176100,176200,235200,61263 ( 260) 400 93.9 4.4e-19
XP_011507765 (OMIM: 600764) PREDICTED: major histo ( 254) 397 93.3 6.7e-19
XP_016866304 (OMIM: 143110) PREDICTED: HLA class I ( 228) 388 91.3 2.3e-18
XP_016866303 (OMIM: 143110) PREDICTED: HLA class I ( 324) 388 91.4 3.1e-18
NP_001170990 (OMIM: 600169) MHC class I polypeptid ( 332) 351 83.6 7.3e-16
NP_001307581 (OMIM: 188370) T-cell surface glycopr ( 316) 334 79.9 8.5e-15
NP_005922 (OMIM: 602436) MHC class I polypeptide-r ( 383) 333 79.8 1.2e-14
NP_000238 (OMIM: 600169) MHC class I polypeptide-r ( 383) 333 79.8 1.2e-14
NP_001754 (OMIM: 188370) T-cell surface glycoprote ( 327) 320 77.0 6.9e-14
NP_001181928 (OMIM: 600764) major histocompatibili ( 296) 317 76.3 9.9e-14
NP_001755 (OMIM: 188360) T-cell surface glycoprote ( 333) 311 75.1 2.6e-13
NP_001757 (OMIM: 188410) antigen-presenting glycop ( 335) 308 74.4 4.1e-13
XP_011508427 (OMIM: 188410) PREDICTED: antigen-pre ( 335) 308 74.4 4.1e-13
NP_001276089 (OMIM: 602436) MHC class I polypeptid ( 351) 299 72.5 1.6e-12
NP_001181929 (OMIM: 600764) major histocompatibili ( 249) 283 69.0 1.3e-11
NP_001181964 (OMIM: 600764) major histocompatibili ( 214) 278 67.9 2.4e-11
XP_011508429 (OMIM: 188410) PREDICTED: antigen-pre ( 231) 278 67.9 2.5e-11
XP_006711684 (OMIM: 188410) PREDICTED: antigen-pre ( 231) 278 67.9 2.5e-11
XP_005245640 (OMIM: 188410) PREDICTED: antigen-pre ( 231) 278 67.9 2.5e-11
>>NP_004098 (OMIM: 601437) IgG receptor FcRn large subun (365 aa)
initn: 2530 init1: 2530 opt: 2530 Z-score: 2907.9 bits: 546.7 E(85289): 3.1e-155
Smith-Waterman score: 2530; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KB6 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV
310 320 330 340 350 360
pF1KB6 IPATA
:::::
NP_004 IPATA
>>NP_001129491 (OMIM: 601437) IgG receptor FcRn large su (365 aa)
initn: 2530 init1: 2530 opt: 2530 Z-score: 2907.9 bits: 546.7 E(85289): 3.1e-155
Smith-Waterman score: 2530; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KB6 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV
310 320 330 340 350 360
pF1KB6 IPATA
:::::
NP_001 IPATA
>>XP_005258714 (OMIM: 601437) PREDICTED: IgG receptor Fc (225 aa)
initn: 1544 init1: 1544 opt: 1544 Z-score: 1778.5 bits: 337.0 E(85289): 2.5e-92
Smith-Waterman score: 1544; 100.0% identity (100.0% similar) in 225 aa overlap (141-365:1-225)
120 130 140 150 160 170
pF1KB6 YTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKA
::::::::::::::::::::::::::::::
XP_005 MNFDLKQGTWGGDWPEALAISQRWQQQDKA
10 20 30
180 190 200 210 220 230
pF1KB6 ANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPE
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB6 LQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVEL
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB6 ESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESPAKSSVLVVGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEA
160 170 180 190 200 210
360
pF1KB6 QDADLKDVNVIPATA
:::::::::::::::
XP_005 QDADLKDVNVIPATA
220
>>XP_011524929 (OMIM: 601437) PREDICTED: IgG receptor Fc (273 aa)
initn: 1138 init1: 1112 opt: 1113 Z-score: 1282.2 bits: 245.4 E(85289): 1.1e-64
Smith-Waterman score: 1678; 74.8% identity (74.8% similar) in 365 aa overlap (1-365:1-273)
10 20 30 40 50 60
pF1KB6 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCE
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGGK------------
70 80 90 100
130 140 150 160 170 180
pF1KB6 LGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLF
XP_011 ------------------------------------------------------------
190 200 210 220 230 240
pF1KB6 SCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL
::::::::::::::::::::::::::::::::::::::::
XP_011 --------------------EPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGL
110 120 130 140
250 260 270 280 290 300
pF1KB6 AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPAKSSVLV
150 160 170 180 190 200
310 320 330 340 350 360
pF1KB6 VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGIVIGVLLLTAAAVGGALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDADLKDVNV
210 220 230 240 250 260
pF1KB6 IPATA
:::::
XP_011 IPATA
270
>>NP_001522 (OMIM: 600764) major histocompatibility comp (341 aa)
initn: 482 init1: 167 opt: 537 Z-score: 619.3 bits: 123.1 E(85289): 9.4e-28
Smith-Waterman score: 541; 29.7% identity (59.3% similar) in 344 aa overlap (11-347:9-339)
10 20 30 40 50 60
pF1KB6 MGVPRPQPWALGLLLFLLPGSLGAESHLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLS
: :.. :. ...: :: : .::.: :.: : :.. . .
NP_001 MGELMAFLLPLIIVLMVKHSDSRTH-SLRYFRLGVSDPIHGVPEFISVGYVDSHPITT
10 20 30 40 50
70 80 90 100 110
pF1KB6 YNSLRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKAL----GGKGPYTLQGL
:.:. . :: . :. :: . .::. : :: ...: .: : . .: .: : .
NP_001 YDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 LGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELT
.:::: :.... ..: .:..:. :. .: . : .:.: :. ... . .
NP_001 IGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 FLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFL
.: : :.. :: :. .:. ::: .:.. . . :: ..: :.: .:::::. . ..
NP_001 WLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 RNG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESPA
.:: .. ::. :..::...: .:. . . . : : :.: :. . :.: ::
NP_001 KNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQES--
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 KSSVLVVGIVIGVLLLTAAAVG-GALLWRRMRSGLPAPWISLRGDDTGVLLPTPGEAQDA
.. ::. : : ..:. . .: :.:.::: : : .. .. ::::
NP_001 ETIPLVMKAVSGSIVLVIVLAGVGVLVWRRR------P----REQNGAIYLPTPDR
300 310 320 330 340
360
pF1KB6 DLKDVNVIPATA
>>NP_005505 (OMIM: 106300,142830,608579) major histocomp (362 aa)
initn: 315 init1: 176 opt: 516 Z-score: 594.8 bits: 118.6 E(85289): 2.2e-26
Smith-Waterman score: 518; 30.3% identity (60.4% similar) in 333 aa overlap (14-327:9-338)
10 20 30 40 50
pF1KB6 MGVPRPQPWALGLLLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGP
.:.:: ..:. : :: :. : :.:: :. : : : :..
NP_005 MLVMAPRTVLLLLSAALALTETWAGSH-SMRYFYTSVSRPGRGEPRFISVGYVDD
10 20 30 40 50
60 70 80 90 100
pF1KB6 QQYLSYNS--LRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------
:.. ..: . :: . :. :.. ::...: . . . :... : :
NP_005 TQFVRFDSDAASPREEPRAPWI-EQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 KGPYTLQGLLGCELGPDNTSV-PTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQ
: .:::.. ::..:::. . ..: .:.... .. .: . : :.:: .
NP_005 AGSHTLQSMYGCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAA-DTAAQITQRKWE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 QDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSF
. :... ..: : . ::..:: :. .:: .::. .. .: : ..: : :..:
NP_005 AAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEATLRCWALGF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 YPPELQLRFLRNG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQ
:: :. : . :.: . : . : .: .:. ....: ::.:..: : ::: :: .
NP_005 YPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPK
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB6 PLRVELESPAKSSVLVVGIVIGVLLLTAAAVGG---ALLWRRMRSGLPAPWISLRGDDTG
:: .. : ..:.: .:::: :. .:.....:. :.. :: ::
NP_005 PLTLRWEPSSQSTVPIVGIVAGLAVLAVVVIGAVVAAVMCRRKSSGGKGGSYSQAACSDS
300 310 320 330 340 350
350 360
pF1KB6 VLLPTPGEAQDADLKDVNVIPATA
NP_005 AQGSDVSLTA
360
>>NP_001229971 (OMIM: 142840,177900,609423) HLA class I (366 aa)
initn: 367 init1: 183 opt: 511 Z-score: 589.0 bits: 117.6 E(85289): 4.6e-26
Smith-Waterman score: 521; 31.7% identity (59.3% similar) in 334 aa overlap (14-327:9-339)
10 20 30 40 50
pF1KB6 MGVPRPQPWALGLLLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGP
::.:: :.:. : :: :. : :::: :. : : : :..
NP_001 MRVMAPRALLLLLSGGLALTETWACSH-SMRYFDTAVSRPGRGEPRFISVGYVDD
10 20 30 40 50
60 70 80 90 100
pF1KB6 QQYLSYNS--LRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------
:.. ..: ..:: . :: :.. ::..:: . . . . ... : :
NP_001 TQFVRFDSDAASPRGEPRAPWV-EQEGPEYWDRETQNYKRQAQADRVSLRNLRGYYNQSE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 KGPYTLQGLLGCELGPDNTSV-PTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQ
: .::: . ::.::::. . . : .:.... .. .: . : :.:: .
NP_001 DGSHTLQRMYGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAA-DTAAQITQRKLE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 QDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSF
.::.. ..: .: . ::..:: :. .:. :::. .. .: : ..: : :..:
NP_001 AARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 YPPELQLRFLRNG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQ
:: :. : . :.: . : . : .::.:. ....: ::.:..: : .:: :: .
NP_001 YPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQE
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB6 PLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGA----LLWRRMRSGLPAPWISLRGDDT
:: . : .. .. ..::: :. .:.. :: :: .. :: ::
NP_001 PLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSN
300 310 320 330 340 350
350 360
pF1KB6 GVLLPTPGEAQDADLKDVNVIPATA
NP_001 SAQGSDESLITCKA
360
>>XP_011512866 (OMIM: 143110) PREDICTED: HLA class I his (343 aa)
initn: 387 init1: 187 opt: 507 Z-score: 584.8 bits: 116.7 E(85289): 7.8e-26
Smith-Waterman score: 521; 32.1% identity (61.0% similar) in 336 aa overlap (14-327:6-335)
10 20 30 40 50
pF1KB6 MGVPRPQPWALGLLLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGP
::.:: :.:. : :: :: : :::: :. : : . . ..
XP_011 MAPRSLLLLLSGALALTDTWAGSH-SLRYFSTAVSRPGRGEPRYIAVEYVDD
10 20 30 40 50
60 70 80 90 100
pF1KB6 QQYLSYNSLRG--EAEPCGAWVWENQVSWYWEKET--------TDLRIKEKLFLEAFKAL
:.: ..: . . :: :: :.. ::: : :: :. . .:. ..
XP_011 TQFLRFDSDAAIPRMEPREPWV-EQEGPQYWEWTTGYAKANAQTD-RVALRNLLRRYNQ-
60 70 80 90 100
110 120 130 140 150 160
pF1KB6 GGKGPYTLQGLLGCELGPDNTSV-PTAKFALNGEEFMNFDLKQGTWGGDWPEALA-ISQR
. : .::::. ::..:::. . . : .:....... .: . ...: :.::
XP_011 SEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTA--ADTVAQITQR
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 WQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSA
. . .. :.. :.: : . ::..:: :. .:. .::. .. .: : ..: : :
XP_011 FYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWA
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB6 FSFYPPELQLRFLRNG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAG
..::: :. : . :.: . : . : .::.:. ....: :.:..: : ::: :
XP_011 LGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEG
230 240 250 260 270 280
290 300 310 320 330
pF1KB6 LAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGG---ALLWRRMRSGLPAPWISLRGD
: ::: .. :. . .. .:::: :...: :...:. :..::. ::
XP_011 LPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSGKLTHTGVQ
290 300 310 320 330 340
340 350 360
pF1KB6 DTGVLLPTPGEAQDADLKDVNVIPATA
>>NP_002108 (OMIM: 142840,177900,609423) HLA class I his (366 aa)
initn: 337 init1: 181 opt: 506 Z-score: 583.2 bits: 116.5 E(85289): 9.5e-26
Smith-Waterman score: 516; 31.7% identity (59.0% similar) in 334 aa overlap (14-327:9-339)
10 20 30 40 50
pF1KB6 MGVPRPQPWALGLLLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGP
::.:: :.:. : :: :. : :::: :. : : : :..
NP_002 MRVMAPRALLLLLSGGLALTETWACSH-SMRYFDTAVSRPGRGEPRFISVGYVDD
10 20 30 40 50
60 70 80 90 100
pF1KB6 QQYLSYNS--LRGEAEPCGAWVWENQVSWYWEKETTDLRIKEKLFLEAFKALGG------
:.. ..: ..:: . :: :.. ::..:: . . . ... : :
NP_002 TQFVRFDSDAASPRGEPRAPWV-EQEGPEYWDRETQKYKRQAQADRVSLRNLRGYYNQSE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB6 KGPYTLQGLLGCELGPDNTSV-PTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQ
: .::: . ::.::::. . . : .:.... .. .: . : :.:: .
NP_002 DGSHTLQRMSGCDLGPDGRLLRGYDQSAYDGKDYIALNEDLRSWTAA-DTAAQITQRKLE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB6 QDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSF
.::.. ..: .: . ::..:: :. .:. :::. .. .: : ..: : :..:
NP_002 AARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSDHEATLRCWALGF
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB6 YPPELQLRFLRNG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQ
:: :. : . :.: . : . : .::.:. ....: ::.:..: : .:: :: .
NP_002 YPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQE
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB6 PLRVELESPAKSSVLVVGIVIGVLLLTAAAVGGA----LLWRRMRSGLPAPWISLRGDDT
:: . : .. .. ..::: :. .:.. :: :: .. :: ::
NP_002 PLTLSWEPSSQPTIPIMGIVAGLAVLVVLAVLGAVVTAMMCRRKSSGGKGGSCSQAACSN
300 310 320 330 340 350
350 360
pF1KB6 GVLLPTPGEAQDADLKDVNVIPATA
NP_002 SAQGSDESLITCKA
360
>>NP_061823 (OMIM: 143110) HLA class I histocompatibilit (346 aa)
initn: 415 init1: 187 opt: 499 Z-score: 575.5 bits: 115.0 E(85289): 2.6e-25
Smith-Waterman score: 513; 31.9% identity (60.9% similar) in 335 aa overlap (14-326:6-334)
10 20 30 40 50
pF1KB6 MGVPRPQPWALGLLLFLLPGSLG-----AESHLSLLYHLTAVSSPAPGTPAFWVSGWLGP
::.:: :.:. : :: :: : :::: :. : : . . ..
NP_061 MAPRSLLLLLSGALALTDTWAGSH-SLRYFSTAVSRPGRGEPRYIAVEYVDD
10 20 30 40 50
60 70 80 90 100
pF1KB6 QQYLSYNSLRG--EAEPCGAWVWENQVSWYWEKET--------TDLRIKEKLFLEAFKAL
:.: ..: . . :: :: :.. ::: : :: :. . .:. ..
NP_061 TQFLRFDSDAAIPRMEPREPWV-EQEGPQYWEWTTGYAKANAQTD-RVALRNLLRRYNQ-
60 70 80 90 100
110 120 130 140 150 160
pF1KB6 GGKGPYTLQGLLGCELGPDNTSV-PTAKFALNGEEFMNFDLKQGTWGGDWPEALA-ISQR
. : .::::. ::..:::. . . : .:....... .: . ...: :.::
NP_061 SEAGSHTLQGMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTA--ADTVAQITQR
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 WQQQDKAANKELTFLLFSCPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSA
. . .. :.. :.: : . ::..:: :. .:. .::. .. .: : ..: : :
NP_061 FYEAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWA
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB6 FSFYPPELQLRFLRNG--LAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAG
..::: :. : . :.: . : . : .::.:. ....: :.:..: : ::: :
NP_061 LGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEG
230 240 250 260 270 280
290 300 310 320 330
pF1KB6 LAQPLRVELESPAKSSVLVVGIVIGVLLLTAAAVGG---ALLWRRMRSGLPAPWISLRGD
: ::: .. :. . .. .:::: :...: :...:. :..::. :
NP_061 LPQPLILRWEQSPQPTIPIVGIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAV
290 300 310 320 330 340
340 350 360
pF1KB6 DTGVLLPTPGEAQDADLKDVNVIPATA
365 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:06:25 2016 done: Fri Nov 4 21:06:27 2016
Total Scan time: 9.360 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]