Result of FASTA (omim) for
pF1KB6502
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6502, 381 aa
1>>>pF1KB6502 381 - 381 aa - 381 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2437+/-0.00036; mu= 11.9124+/- 0.023
mean_var=89.3303+/-18.015, 0's: 0 Z-trim(115.1): 119 B-trim: 33 in 1/49
Lambda= 0.135698
statistics sampled from 25227 (25346) to 25227 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.297), width: 16
Scan time: 6.790
The best scores are: opt bits E(85289)
NP_001937 (OMIM: 602748,615269) dual specificity p ( 381) 2531 505.6 7.6e-143
NP_001938 (OMIM: 602749) dual specificity protein ( 419) 1783 359.2 1e-98
XP_011529426 (OMIM: 300134) PREDICTED: dual specif ( 384) 1048 215.3 1.9e-55
NP_001386 (OMIM: 300134) dual specificity protein ( 384) 1048 215.3 1.9e-55
NP_001305432 (OMIM: 300134) dual specificity prote ( 384) 1048 215.3 1.9e-55
XP_011529425 (OMIM: 300134) PREDICTED: dual specif ( 415) 1048 215.3 2e-55
NP_073143 (OMIM: 602748,615269) dual specificity p ( 235) 882 182.7 7.7e-46
XP_016859035 (OMIM: 603068) PREDICTED: dual specif ( 342) 543 116.4 1e-25
NP_009138 (OMIM: 608867) dual specificity protein ( 482) 479 104.0 7.9e-22
XP_011542730 (OMIM: 602747) PREDICTED: dual specif ( 303) 472 102.5 1.4e-21
NP_476499 (OMIM: 602747) dual specificity protein ( 303) 472 102.5 1.4e-21
NP_001385 (OMIM: 602747) dual specificity protein ( 394) 472 102.5 1.7e-21
NP_004408 (OMIM: 600714) dual specificity protein ( 367) 470 102.1 2.1e-21
XP_011518235 (OMIM: 602038) PREDICTED: dual specif ( 625) 468 101.9 4.4e-21
NP_004411 (OMIM: 602038) dual specificity protein ( 625) 468 101.9 4.4e-21
XP_011518234 (OMIM: 602038) PREDICTED: dual specif ( 625) 468 101.9 4.4e-21
NP_004409 (OMIM: 603068) dual specificity protein ( 314) 460 100.1 7.3e-21
NP_085143 (OMIM: 607175) dual specificity protein ( 665) 446 97.6 9.2e-20
XP_011519158 (OMIM: 607175) PREDICTED: dual specif ( 665) 446 97.6 9.2e-20
XP_006719218 (OMIM: 607175) PREDICTED: dual specif ( 665) 446 97.6 9.2e-20
XP_011519159 (OMIM: 607175) PREDICTED: dual specif ( 665) 446 97.6 9.2e-20
NP_004410 (OMIM: 603069) dual specificity protein ( 384) 414 91.2 4.4e-18
XP_005253545 (OMIM: 607175) PREDICTED: dual specif ( 517) 360 80.7 8.7e-15
XP_016875477 (OMIM: 607175) PREDICTED: dual specif ( 517) 360 80.7 8.7e-15
NP_001154802 (OMIM: 606778) protein phosphatase Sl ( 692) 334 75.7 3.8e-13
NP_001154803 (OMIM: 606778) protein phosphatase Sl ( 703) 334 75.7 3.8e-13
XP_016874981 (OMIM: 606778) PREDICTED: protein pho ( 923) 334 75.7 4.8e-13
XP_005269042 (OMIM: 606778) PREDICTED: protein pho ( 969) 334 75.7 5e-13
XP_011536803 (OMIM: 606778) PREDICTED: protein pho ( 969) 334 75.7 5e-13
XP_011536802 (OMIM: 606778) PREDICTED: protein pho ( 969) 334 75.7 5e-13
XP_016874980 (OMIM: 606778) PREDICTED: protein pho (1033) 334 75.7 5.3e-13
NP_061857 (OMIM: 606778) protein phosphatase Sling (1049) 334 75.7 5.4e-13
XP_005269041 (OMIM: 606778) PREDICTED: protein pho (1049) 334 75.7 5.4e-13
XP_011536799 (OMIM: 606778) PREDICTED: protein pho (1060) 334 75.7 5.4e-13
NP_064570 (OMIM: 616778) dual specificity protein ( 184) 320 72.6 8.2e-13
NP_001273484 (OMIM: 616778) dual specificity prote ( 205) 320 72.6 9e-13
XP_016880743 (OMIM: 606779) PREDICTED: protein pho ( 480) 315 71.9 3.7e-12
NP_543152 (OMIM: 611437) dual specificity protein ( 217) 310 70.7 3.7e-12
XP_016880742 (OMIM: 606779) PREDICTED: protein pho ( 529) 315 71.9 4e-12
XP_016880741 (OMIM: 606779) PREDICTED: protein pho (1328) 319 72.9 5e-12
XP_011523708 (OMIM: 606779) PREDICTED: protein pho (1347) 319 72.9 5.1e-12
XP_011523709 (OMIM: 606779) PREDICTED: protein pho (1347) 319 72.9 5.1e-12
XP_011523707 (OMIM: 606779) PREDICTED: protein pho (1394) 319 72.9 5.2e-12
XP_006722212 (OMIM: 606779) PREDICTED: protein pho (1401) 319 72.9 5.3e-12
XP_011523706 (OMIM: 606779) PREDICTED: protein pho (1405) 319 72.9 5.3e-12
NP_203747 (OMIM: 606779) protein phosphatase Sling (1423) 319 72.9 5.3e-12
XP_011523704 (OMIM: 606779) PREDICTED: protein pho (1430) 319 72.9 5.4e-12
XP_005258116 (OMIM: 606779) PREDICTED: protein pho (1430) 319 72.9 5.4e-12
XP_016880740 (OMIM: 606779) PREDICTED: protein pho (1449) 319 72.9 5.4e-12
XP_005258115 (OMIM: 606779) PREDICTED: protein pho (1450) 319 72.9 5.4e-12
>>NP_001937 (OMIM: 602748,615269) dual specificity prote (381 aa)
initn: 2531 init1: 2531 opt: 2531 Z-score: 2685.5 bits: 505.6 E(85289): 7.6e-143
Smith-Waterman score: 2531; 99.7% identity (100.0% similar) in 381 aa overlap (1-381:1-381)
10 20 30 40 50 60
pF1KB6 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESLLGLLLK
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
NP_001 IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
310 320 330 340 350 360
370 380
pF1KB6 QLYFTTPSNQNVYQVDSLQST
:::::::::::::::::::::
NP_001 QLYFTTPSNQNVYQVDSLQST
370 380
>>NP_001938 (OMIM: 602749) dual specificity protein phos (419 aa)
initn: 1430 init1: 1398 opt: 1783 Z-score: 1893.4 bits: 359.2 E(85289): 1e-98
Smith-Waterman score: 1783; 71.7% identity (90.7% similar) in 367 aa overlap (18-381:55-419)
10 20 30 40
pF1KB6 MIDTLRPVPFASEMAISKTVAWLNEQLEL-GNERLLLMDCRPQELYE
:.. ::.:.:: :. :::.::::.::.:
NP_001 TRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWLQEELEARGGASLLLLDCRPHELFE
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB6 SSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWN
:::::.:::.::::.:::::.:::::.:... :..::. :: . ::.::::....:.
NP_001 SSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHADKERFATRCKAATVLLYDEATAEWQ
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB6 ENTGGE-SLLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCS-SSSPPLPV
. :. :.:::::.::.:.::.:.::.:::.:::.:.: :::::.:.: : ::::: :
NP_001 PEPGAPASVLGLLLQKLRDDGCQAYYLQGGFNKFQTEYSEHCETNVDSSSSPSSSPPTSV
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB6 LGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTN
::::::::::: : : ::: . :.:::.:::::. .:::.:::.:::.:::::::::::
NP_001 LGLGGLRISSDCS-DGESDREL-PSSATESDGSPVPSSQPAFPVQILPYLYLGCAKDSTN
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB6 LDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARG
:::: ..:::::::::::::: ::..::: :::::::::::::::::::::::::::::.
NP_001 LDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARS
270 280 290 300 310 320
290 300 310 320 330 340
pF1KB6 KNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFE
:.:::::::::::::::::::::::::.:::.:::::.:: :::::::::::::::::::
NP_001 KKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFE
330 340 350 360 370 380
350 360 370 380
pF1KB6 RTLGLSSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST
:::::::::::.. ..::::.::.:.:.. ...:.::
NP_001 RTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST
390 400 410
>>XP_011529426 (OMIM: 300134) PREDICTED: dual specificit (384 aa)
initn: 1198 init1: 791 opt: 1048 Z-score: 1116.4 bits: 215.3 E(85289): 1.9e-55
Smith-Waterman score: 1217; 54.2% identity (75.3% similar) in 384 aa overlap (16-375:4-381)
10 20 30 40 50 60
pF1KB6 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
.... :: ..: ::::.::: .:::::..: .:..::.:.
XP_011 MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPA
10 20 30 40
70 80 90 100 110
pF1KB6 IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWN--------ENTGGE
..::::..:.: ::::. : . :.:::.... :. .:
XP_011 LLLRRLRRGSLSVRALLP-GPP----LQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAE
50 60 70 80 90 100
120 130 140 150 160
pF1KB6 SLLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSS-SP---PLPVLGLG
:.:: ::.::..:: :.::.::::.:::: :::.: : .:: .: :.::.:::
XP_011 SVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLG
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 GLRISSDSSSDIESDLDRDPNS-ATDSDGS--PLSNSQPSFPVEILPFLYLGCAKDSTNL
.: ..:: : : ::. ::: : . ::.:. : . . ::::.::: :::: :.::.::
XP_011 SLCLGSDCS-DAESEADRDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB6 DVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGK
. : ..::.:::::::::::.::. :.:.:::::::::::::::.:::::: ::::: ..
XP_011 ESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQ
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB6 NCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFER
:::::::::::.:::::::::::::::.::.:::::.:: ::::::::::::::::::::
XP_011 NCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFER
290 300 310 320 330 340
350 360 370 380
pF1KB6 TLGL---------SSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST
.: : :. . . .::::........
XP_011 SLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT
350 360 370 380
>>NP_001386 (OMIM: 300134) dual specificity protein phos (384 aa)
initn: 1198 init1: 791 opt: 1048 Z-score: 1116.4 bits: 215.3 E(85289): 1.9e-55
Smith-Waterman score: 1217; 54.2% identity (75.3% similar) in 384 aa overlap (16-375:4-381)
10 20 30 40 50 60
pF1KB6 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
.... :: ..: ::::.::: .:::::..: .:..::.:.
NP_001 MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPA
10 20 30 40
70 80 90 100 110
pF1KB6 IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWN--------ENTGGE
..::::..:.: ::::. : . :.:::.... :. .:
NP_001 LLLRRLRRGSLSVRALLP-GPP----LQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAE
50 60 70 80 90 100
120 130 140 150 160
pF1KB6 SLLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSS-SP---PLPVLGLG
:.:: ::.::..:: :.::.::::.:::: :::.: : .:: .: :.::.:::
NP_001 SVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLG
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 GLRISSDSSSDIESDLDRDPNS-ATDSDGS--PLSNSQPSFPVEILPFLYLGCAKDSTNL
.: ..:: : : ::. ::: : . ::.:. : . . ::::.::: :::: :.::.::
NP_001 SLCLGSDCS-DAESEADRDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB6 DVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGK
. : ..::.:::::::::::.::. :.:.:::::::::::::::.:::::: ::::: ..
NP_001 ESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQ
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB6 NCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFER
:::::::::::.:::::::::::::::.::.:::::.:: ::::::::::::::::::::
NP_001 NCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFER
290 300 310 320 330 340
350 360 370 380
pF1KB6 TLGL---------SSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST
.: : :. . . .::::........
NP_001 SLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT
350 360 370 380
>>NP_001305432 (OMIM: 300134) dual specificity protein p (384 aa)
initn: 1198 init1: 791 opt: 1048 Z-score: 1116.4 bits: 215.3 E(85289): 1.9e-55
Smith-Waterman score: 1217; 54.2% identity (75.3% similar) in 384 aa overlap (16-375:4-381)
10 20 30 40 50 60
pF1KB6 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
.... :: ..: ::::.::: .:::::..: .:..::.:.
NP_001 MEGLGRSCLWLRRELSPPRPRLLLLDCRSRELYESARIGGALSVALPA
10 20 30 40
70 80 90 100 110
pF1KB6 IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWN--------ENTGGE
..::::..:.: ::::. : . :.:::.... :. .:
NP_001 LLLRRLRRGSLSVRALLP-GPP----LQPPPPAPVLLYDQGGGRRRRGEAEAEAEEWEAE
50 60 70 80 90 100
120 130 140 150 160
pF1KB6 SLLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSS-SP---PLPVLGLG
:.:: ::.::..:: :.::.::::.:::: :::.: : .:: .: :.::.:::
NP_001 SVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCETSLAGRAGSSMAPVPGPVPVVGLG
110 120 130 140 150 160
170 180 190 200 210 220
pF1KB6 GLRISSDSSSDIESDLDRDPNS-ATDSDGS--PLSNSQPSFPVEILPFLYLGCAKDSTNL
.: ..:: : : ::. ::: : . ::.:. : . . ::::.::: :::: :.::.::
NP_001 SLCLGSDCS-DAESEADRDSMSCGLDSEGATPPPVGLRASFPVQILPNLYLGSARDSANL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KB6 DVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGK
. : ..::.:::::::::::.::. :.:.:::::::::::::::.:::::: ::::: ..
NP_001 ESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSRFFPEAIEFIDEALSQ
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB6 NCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFER
:::::::::::.:::::::::::::::.::.:::::.:: ::::::::::::::::::::
NP_001 NCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNISPNFNFMGQLLDFER
290 300 310 320 330 340
350 360 370 380
pF1KB6 TLGL---------SSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST
.: : :. . . .::::........
NP_001 SLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT
350 360 370 380
>>XP_011529425 (OMIM: 300134) PREDICTED: dual specificit (415 aa)
initn: 1198 init1: 791 opt: 1048 Z-score: 1115.9 bits: 215.3 E(85289): 2e-55
Smith-Waterman score: 1217; 54.2% identity (75.3% similar) in 384 aa overlap (16-375:35-412)
10 20 30 40
pF1KB6 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELY
.... :: ..: ::::.::: .:::
XP_011 QVGPKGRQLPGKHVVAPVVQRVGSRSPMEGLGRSCLWLRRELSPPRPRLLLLDCRSRELY
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB6 ESSHIESAINVAIPGIMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDW
::..: .:..::.:...::::..:.: ::::. : . :.:::....
XP_011 ESARIGGALSVALPALLLRRLRRGSLSVRALLP-GPP----LQPPPPAPVLLYDQGGGRR
70 80 90 100 110
110 120 130 140 150
pF1KB6 N--------ENTGGESLLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSS
:. .::.:: ::.::..:: :.::.::::.:::: :::.: : .:
XP_011 RRGEAEAEAEEWEAESVLGTLLQKLREEGYLAYYLQGGFSRFQAECPHLCETSLAGRAGS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 S-SP---PLPVLGLGGLRISSDSSSDIESDLDRDPNS-ATDSDGS--PLSNSQPSFPVEI
: .: :.::.:::.: ..:: : : ::. ::: : . ::.:. : . . ::::.:
XP_011 SMAPVPGPVPVVGLGSLCLGSDCS-DAESEADRDSMSCGLDSEGATPPPVGLRASFPVQI
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 LPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQ
:: :::: :.::.::. : ..::.:::::::::::.::. :.:.:::::::::::::::.
XP_011 LPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNLSR
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 FFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNI
:::::: ::::: ..:::::::::::.:::::::::::::::.::.:::::.:: :::::
XP_011 FFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKSNI
300 310 320 330 340 350
340 350 360 370 380
pF1KB6 SPNFNFMGQLLDFERTLGL---------SSPCDNRVPAQQLYFTTPSNQNVYQVDSLQST
:::::::::::::::.: : :. . . .::::........
XP_011 SPNFNFMGQLLDFERSLRLEERHSQEQGSGGQASAASNPPSFFTTPTSDGAFELAPT
360 370 380 390 400 410
>>NP_073143 (OMIM: 602748,615269) dual specificity prote (235 aa)
initn: 879 init1: 879 opt: 882 Z-score: 944.0 bits: 182.7 E(85289): 7.7e-46
Smith-Waterman score: 1244; 61.4% identity (61.7% similar) in 381 aa overlap (1-381:1-235)
10 20 30 40 50 60
pF1KB6 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 MIDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESLLGLLLK
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
NP_073 IMLRRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESVLGLLLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 KLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSDI
:::::::::::::
NP_073 KLKDEGCRAFYLE-----------------------------------------------
130
190 200 210 220 230 240
pF1KB6 ESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVT
NP_073 ------------------------------------------------------------
250 260 270 280 290 300
pF1KB6 PNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRS
:::::::::::::::::::::
NP_073 ---------------------------------------DEARGKNCGVLVHCLAGISRS
140 150
310 320 330 340 350 360
pF1KB6 VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_073 VTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQ
160 170 180 190 200 210
370 380
pF1KB6 QLYFTTPSNQNVYQVDSLQST
:::::::::::::::::::::
NP_073 QLYFTTPSNQNVYQVDSLQST
220 230
>>XP_016859035 (OMIM: 603068) PREDICTED: dual specificit (342 aa)
initn: 573 init1: 332 opt: 543 Z-score: 582.8 bits: 116.4 E(85289): 1e-25
Smith-Waterman score: 543; 36.1% identity (61.7% similar) in 324 aa overlap (32-344:25-336)
10 20 30 40 50 60
pF1KB6 IDTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIP-G
:: ::.:::: . :...: .: .
XP_016 MGLEAARELECAALGTLLRDPREAERTLLLDCRPFLAFCRRHVRAA--RPVPWN
10 20 30 40 50
70 80 90 100 110
pF1KB6 IMLRRLQKGNLPVRALFTRGEDRDRFTR--RCGTDTVVLYDESSSDWNE---NTGGESLL
.::: .: :. .: :: :: : .:. ::.:.. : .. .. ::
XP_016 ALLRRRARGP-PAAVLACLLPDRALRTRLVRGELARAVVLDEGSASVAELRPDSPAHVLL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSD
. ::.. . ...:.: :: . . . .. ::.:. ::. .
XP_016 AALLHETRAGPTAVYFLRG----EQAGRPWPAPPDSSPAFPADRA-LPLLA-GGFDGFQG
120 130 140 150 160
180 190 200 210 220 230
pF1KB6 SSSDIESDLDRDPNSATDSDGSPLSNSQ-PSF----PVEILPFLYLGCAKDSTNLDVLEE
:. :. : .: . :.:. : . ::::::.:.:: . :..:. :.
XP_016 CCPDLCSEAPA-PALPPTGDKTSRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQA
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 FGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVL
:: .:::. . :: :: : :.::.::. :. ..: .: :::.::: ..... ::
XP_016 CGITAVLNVSASCPNHFE--GLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVL
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB6 VHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLS
::: ::::::.:. .:::::. . ...:.:.::.... :::::.::::::.::
XP_016 VHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH
290 300 310 320 330 340
360 370 380
pF1KB6 SPCDNRVPAQQLYFTTPSNQNVYQVDSLQST
>>NP_009138 (OMIM: 608867) dual specificity protein phos (482 aa)
initn: 638 init1: 477 opt: 479 Z-score: 512.8 bits: 104.0 E(85289): 7.9e-22
Smith-Waterman score: 646; 37.1% identity (67.3% similar) in 315 aa overlap (35-347:173-462)
10 20 30 40 50 60
pF1KB6 LRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPG-IML
...:::: :..:::..:... :
NP_009 QLASIKIIYPNDLAKKMTKCSKSHLPSQGPVIIDCRPFMEYNKSHIQGAVHINCADKISR
150 160 170 180 190 200
70 80 90 100 110 120
pF1KB6 RRLQKGNLPVRALFTRGEDRDRFTRRCGTDTVVLYDESSSDWNENTGGESLLGLLLKKLK
::::.:.. : :.. : .: : .: . ...:::.... .. .. : ..:..::
NP_009 RRLQQGKITVLDLISCREGKDSF-KRIFSKEIIVYDENTNEPSRVMPSQPL-HIVLESLK
210 220 230 240 250 260
130 140 150 160 170 180
pF1KB6 DEGCRAFYLEGGFSKFQAEFSLHCETNLD-GSCSSSSPPLPVLGLGGLRISSDSSSDIES
:: . . :.::.:.:. . :...:. : .: :: .: .:: . .
NP_009 REGKEPLVLKGGLSSFKQNHENLCDNSLQLQECRE-------VG-GG---ASAASSLLPQ
270 280 290 300
190 200 210 220 230 240
pF1KB6 DLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPN
. : : ... :. : :::::.:: .:. .::......: :..::: .
NP_009 PIPTTP----DIENAELT---P-----ILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTH
310 320 330 340 350
250 260 270 280 290 300
pF1KB6 LPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVT
:: . : :.::..: .: .::: :.: ::. ::.::. . :.:.:: ::.:::.:
NP_009 LPLYHYEKGLFNYKRLPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSAT
360 370 380 390 400 410
310 320 330 340 350 360
pF1KB6 VTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFERTLGLSSPCDNRVPAQQL
...::::.. ..:.::: .:: :. ::::.:::::::.::. :
NP_009 IVIAYLMKHTRMTMTDAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMG
420 430 440 450 460 470
370 380
pF1KB6 YFTTPSNQNVYQVDSLQST
NP_009 VETVV
480
>>XP_011542730 (OMIM: 602747) PREDICTED: dual specificit (303 aa)
initn: 503 init1: 318 opt: 472 Z-score: 508.5 bits: 102.5 E(85289): 1.4e-21
Smith-Waterman score: 485; 37.2% identity (62.1% similar) in 253 aa overlap (127-373:47-275)
100 110 120 130 140 150
pF1KB6 LYDESSSDWNENTGGESLLGLLLKKLKDEGCRAFYLEGGFSKFQAEFSLHCETNLDGSCS
: .::. .:..:. : . . .
XP_011 RSPRRTGRDCKPVRAPSMALGVSQLAGRSRCLCSESQGGYERFSSEYPEFCSKT--KALA
20 30 40 50 60 70
160 170 180 190 200 210
pF1KB6 SSSPPLPVLGLGGLRISSDSSSDIESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYL
. ::.: :. :: . .: :.:: .. ::::::::::
XP_011 AIPPPVP------------PSATEPLDL------GCSSCGTPLHDQGG--PVEILPFLYL
80 90 100 110
220 230 240 250 260 270
pF1KB6 GCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAI
: : .. :.:. .:: .:::. . :: :: :...:: ::. :. . ..:..: :::
XP_011 GSAYHAARRDMLDALGITALLNVSSDCPNHFE--GHYQYKCIPVEDNHKADISSWFMEAI
120 130 140 150 160 170
280 290 300 310 320 330
pF1KB6 SFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNF
.:: .. ::::: ::::::.:. .::::.: . ...:...::...: :::::.:
XP_011 EYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSF
180 190 200 210 220 230
340 350 360 370 380
pF1KB6 MGQLLDFE-RTLGLSSPCDNRVPAQQLYF-----TTPSNQNVYQVDSLQST
:::::.:: ..:. : . :. : .::..: :.
XP_011 MGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPY
240 250 260 270 280 290
XP_011 LHSPITTSPSC
300
381 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:04:07 2016 done: Fri Nov 4 21:04:08 2016
Total Scan time: 6.790 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]