FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6433, 313 aa
  1>>>pF1KB6433 313 - 313 aa - 313 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 7.7628+/-0.000436; mu= 6.7889+/- 0.027
 mean_var=255.0362+/-53.273, 0's: 0 Z-trim(119.4): 34  B-trim: 601 in 1/53
 Lambda= 0.080311
 statistics sampled from 33435 (33469) to 33435 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.723), E-opt: 0.2 (0.392), width:  16
 Scan time:  8.190

The best scores are:                                      opt bits E(85289)
NP_003170 (OMIM: 300802,313475) synaptophysin [Hom ( 313) 2167 263.9 3.1e-70
NP_006745 (OMIM: 616665) synaptophysin-like protei ( 259)  705 94.4 2.7e-19
NP_874384 (OMIM: 616665) synaptophysin-like protei ( 241)  701 93.9 3.5e-19


>>NP_003170 (OMIM: 300802,313475) synaptophysin [Homo sa  (313 aa)
 initn: 2167 init1: 2167 opt: 2167  Z-score: 1382.0  bits: 263.9 E(85289): 3.1e-70
Smith-Waterman score: 2167; 100.0% identity (100.0% similar) in 313 aa overlap (1-313:1-313)

               10        20        30        40        50        60
pF1KB6 MLLLADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLLLADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANK
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 TESDLSIEVEFEYPFRLHQVYFDAPTCRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYSMG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TESDLSIEVEFEYPFRLHQVYFDAPTCRGGTTKVFLVGDYSSSAEFFVTVAVFAFLYSMG
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 ALATYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEM
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ALATYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENIIKEM
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 PVCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PVCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAPPGAP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 EKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPAGSGGSGYGPQGDYGQQGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPAGSGGSGYGPQGDYGQQGY
              250       260       270       280       290       300

              310   
pF1KB6 GPQGAPTSFSNQM
       :::::::::::::
NP_003 GPQGAPTSFSNQM
              310   

>>NP_006745 (OMIM: 616665) synaptophysin-like protein 1   (259 aa)
 initn: 695 init1: 294 opt: 705  Z-score: 467.5  bits: 94.4 E(85289): 2.7e-19
Smith-Waterman score: 705; 43.6% identity (70.4% similar) in 243 aa overlap (10-246:15-256)

                    10        20          30        40        50   
pF1KB6      MLLLADMDVVNQLVAGGQFRV--VKEPLGFVKVLQWVFAIFAFATCGSYSGELQL
                     ..: ..: :. .  .::::::.:::.:. .::::::::...:. ..
NP_006 MAPNIYLVRQRISRLGQRMSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEI
               10        20        30        40        50        60

            60        70        80            90       100         
pF1KB6 SVDCANKTESDLSIEVEFEYPFRLHQVYFDAPT----CRGGTTKVFLVGDYSSSAEFFVT
       .:.:   .  . .. . : :::::... :. :     :  .     :.:::::::.:.::
NP_006 QVNCPPAVTENKTVTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVT
               70        80        90       100       110       120

     110       120       130       140       150       160         
pF1KB6 VAVFAFLYSMGALATYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKM
        :::.::: ..::  :.   . : .. : ::.::..: : .:.::::.:::::.:.:.:.
NP_006 FAVFVFLYCIAALLLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKI
              130       140       150       160       170       180

     170       180       190       200       210       220         
pF1KB6 ATDPENIIKEMPVCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWA
       ::  .::: :.: :.. .  :        ..::.::.:::::..:: :: :::.:::.  
NP_006 ATG-HNIIDELPPCKKKAVLCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLH
               190       200       210       220       230         

     230       240       250       260       270       280         
pF1KB6 APFLRAPPGAPEKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPAGSGGSGY
       .:   . : .    : :                                           
NP_006 SPSNTSAPHSQGGIPPPTGI                                        
     240       250                                                 

>>NP_874384 (OMIM: 616665) synaptophysin-like protein 1   (241 aa)
 initn: 695 init1: 294 opt: 701  Z-score: 465.3  bits: 93.9 E(85289): 3.5e-19
Smith-Waterman score: 701; 45.0% identity (70.7% similar) in 229 aa overlap (22-246:11-238)

               10        20        30        40        50        60
pF1KB6 MLLLADMDVVNQLVAGGQFRVVKEPLGFVKVLQWVFAIFAFATCGSYSGELQLSVDCANK
                            .::::::.:::.:. .::::::::...:. ...:.:   
NP_874            MSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPA
                          10        20        30        40         

               70        80            90       100       110      
pF1KB6 TESDLSIEVEFEYPFRLHQVYFDAPT----CRGGTTKVFLVGDYSSSAEFFVTVAVFAFL
       .  . .. . : :::::... :. :     :  .     :.:::::::.:.:: :::.::
NP_874 VTENKTVTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFL
      50        60        70        80        90       100         

        120       130       140       150       160       170      
pF1KB6 YSMGALATYIFLQNKYRENNKGPMLDFLATAVFAFMWLVSSSAWAKGLSDVKMATDPENI
       : ..::  :.   . : .. : ::.::..: : .:.::::.:::::.:.:.:.::  .::
NP_874 YCIAALLLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATG-HNI
     110       120       130       140       150       160         

        180       190       200       210       220       230      
pF1KB6 IKEMPVCRQTGNTCKELRDPVTSGLNTSVVFGFLNLVLWVGNLWFVFKETGWAAPFLRAP
       : :.: :.. .  :        ..::.::.:::::..:: :: :::.:::.  .:   . 
NP_874 IDELPPCKKKAVLCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSA
      170       180       190       200       210       220        

        240       250       260       270       280       290      
pF1KB6 PGAPEKQPAPGDAYGDAGYGQGPGGYGPQDSYGPQGGYQPDYGQPAGSGGSGYGPQGDYG
       : .    : :                                                  
NP_874 PHSQGGIPPPTGI                                               
      230       240                                                




313 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 22:58:21 2016 done: Fri Nov  4 22:58:22 2016
 Total Scan time:  8.190 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]