Result of FASTA (omim) for
pF1KB6432
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6432, 344 aa
1>>>pF1KB6432 344 - 344 aa - 344 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0667+/-0.000342; mu= 13.2857+/- 0.021
mean_var=86.4471+/-17.068, 0's: 0 Z-trim(116.0): 25 B-trim: 26 in 1/52
Lambda= 0.137943
statistics sampled from 26898 (26922) to 26898 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.694), E-opt: 0.2 (0.316), width: 16
Scan time: 7.600
The best scores are: opt bits E(85289)
NP_057670 (OMIM: 609431) MAP3K12-binding inhibitor ( 344) 2243 456.0 5.3e-128
NP_001138363 (OMIM: 609431) MAP3K12-binding inhibi ( 343) 2224 452.2 7.3e-127
XP_005267813 (OMIM: 609431) PREDICTED: MAP3K12-bin ( 281) 1718 351.5 1.3e-96
NP_001295039 (OMIM: 609431) MAP3K12-binding inhibi ( 282) 1718 351.5 1.3e-96
XP_016876856 (OMIM: 609431) PREDICTED: MAP3K12-bin ( 259) 1216 251.6 1.4e-66
XP_005267811 (OMIM: 609431) PREDICTED: MAP3K12-bin ( 322) 1216 251.6 1.7e-66
>>NP_057670 (OMIM: 609431) MAP3K12-binding inhibitory pr (344 aa)
initn: 2243 init1: 2243 opt: 2243 Z-score: 2419.0 bits: 456.0 E(85289): 5.3e-128
Smith-Waterman score: 2243; 99.4% identity (99.4% similar) in 344 aa overlap (1-344:1-344)
10 20 30 40 50 60
pF1KB6 MAAATEHNRPSSGDRNLERRCSPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
:::::: :::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_057 MAAATELNRPSSGDRNLERRCRPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRPEGIPGSGHKPNSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 EFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRPEGIPGSGHKPNSML
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 RDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVSFSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 RDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVSFSG
250 260 270 280 290 300
310 320 330 340
pF1KB6 KRRKVQPPQQNYSLAELDEKISALKQALLRKSREAESMATHHLP
::::::::::::::::::::::::::::::::::::::::::::
NP_057 KRRKVQPPQQNYSLAELDEKISALKQALLRKSREAESMATHHLP
310 320 330 340
>>NP_001138363 (OMIM: 609431) MAP3K12-binding inhibitory (343 aa)
initn: 2028 init1: 2028 opt: 2224 Z-score: 2398.6 bits: 452.2 E(85289): 7.3e-127
Smith-Waterman score: 2224; 99.1% identity (99.1% similar) in 344 aa overlap (1-344:1-343)
10 20 30 40 50 60
pF1KB6 MAAATEHNRPSSGDRNLERRCSPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
:::::: :::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 MAAATELNRPSSGDRNLERRCRPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRPEGIPGSGHKPNSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRPEGIPGSGHKPNSML
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 RDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVSFSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVSFSG
250 260 270 280 290 300
310 320 330 340
pF1KB6 KRRKVQPPQQNYSLAELDEKISALKQALLRKSREAESMATHHLP
::::::::: ::::::::::::::::::::::::::::::::::
NP_001 KRRKVQPPQ-NYSLAELDEKISALKQALLRKSREAESMATHHLP
310 320 330 340
>>XP_005267813 (OMIM: 609431) PREDICTED: MAP3K12-binding (281 aa)
initn: 1718 init1: 1718 opt: 1718 Z-score: 1855.7 bits: 351.5 E(85289): 1.3e-96
Smith-Waterman score: 1718; 99.2% identity (99.2% similar) in 263 aa overlap (1-263:1-263)
10 20 30 40 50 60
pF1KB6 MAAATEHNRPSSGDRNLERRCSPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
:::::: :::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_005 MAAATELNRPSSGDRNLERRCRPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRPEGIPGSGHKPNSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRPEGIPGSGHKPNSML
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 RDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVSFSG
:::::::::::::::::::::::
XP_005 RDCGNQAVEERLQNIEAHLRLQTELFWKKKKSSTTSKLFTG
250 260 270 280
>>NP_001295039 (OMIM: 609431) MAP3K12-binding inhibitory (282 aa)
initn: 1718 init1: 1718 opt: 1718 Z-score: 1855.7 bits: 351.5 E(85289): 1.3e-96
Smith-Waterman score: 1718; 99.2% identity (99.2% similar) in 263 aa overlap (1-263:1-263)
10 20 30 40 50 60
pF1KB6 MAAATEHNRPSSGDRNLERRCSPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
:::::: :::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_001 MAAATELNRPSSGDRNLERRCRPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRPEGIPGSGHKPNSML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRPEGIPGSGHKPNSML
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 RDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVSFSG
:::::::::::::::::::::::
NP_001 RDCGNQAVEERLQNIEAHLRLQTELFWKKKKSSTTSTELFTG
250 260 270 280
>>XP_016876856 (OMIM: 609431) PREDICTED: MAP3K12-binding (259 aa)
initn: 1216 init1: 1216 opt: 1216 Z-score: 1316.3 bits: 251.6 E(85289): 1.4e-66
Smith-Waterman score: 1509; 90.9% identity (90.9% similar) in 263 aa overlap (1-263:1-241)
10 20 30 40 50 60
pF1KB6 MAAATEHNRPSSGDRNLERRCSPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
:::::: :::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_016 MAAATELNRPSSGDRNLERRCRPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRPEGIPGSGHKPNSML
:::::::::: ::::::::::::::::::::::::::::
XP_016 EFCNVIDCNQ----------------------VSRVVNTYGPQTRPEGIPGSGHKPNSML
190 200 210
250 260 270 280 290 300
pF1KB6 RDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVSFSG
:::::::::::::::::::::::
XP_016 RDCGNQAVEERLQNIEAHLRLQTELFWKKKKSSTTSKLFTG
220 230 240 250
>>XP_005267811 (OMIM: 609431) PREDICTED: MAP3K12-binding (322 aa)
initn: 1216 init1: 1216 opt: 1216 Z-score: 1314.9 bits: 251.6 E(85289): 1.7e-66
Smith-Waterman score: 2034; 93.0% identity (93.0% similar) in 344 aa overlap (1-344:1-322)
10 20 30 40 50 60
pF1KB6 MAAATEHNRPSSGDRNLERRCSPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
:::::: :::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_005 MAAATELNRPSSGDRNLERRCRPNLSREVLYEIFRSLHTLVGQLDLRDDVVKITIDWNKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QSLSAFQPALLFSALEQHILYLQPFLAKLQSPIKEENTTAVEEIGRTEMGNKNEVNDKFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGDLQEEEKHKESDLRDVKKTQIHFDPEVVQIKAGKAEIDRRISAFIERKQAEINENNVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EFCNVIDCNQENSCARTDAIFTPYPGFKSHVKVSRVVNTYGPQTRPEGIPGSGHKPNSML
:::::::::: ::::::::::::::::::::::::::::
XP_005 EFCNVIDCNQ----------------------VSRVVNTYGPQTRPEGIPGSGHKPNSML
190 200 210
250 260 270 280 290 300
pF1KB6 RDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVSFSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RDCGNQAVEERLQNIEAHLRLQTGGPVPRDIYQRIKKLEDKILELEGISPEYFQSVSFSG
220 230 240 250 260 270
310 320 330 340
pF1KB6 KRRKVQPPQQNYSLAELDEKISALKQALLRKSREAESMATHHLP
::::::::::::::::::::::::::::::::::::::::::::
XP_005 KRRKVQPPQQNYSLAELDEKISALKQALLRKSREAESMATHHLP
280 290 300 310 320
344 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:57:47 2016 done: Fri Nov 4 22:57:48 2016
Total Scan time: 7.600 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]