Result of FASTA (omim) for
pF1KB6215
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6215, 669 aa
1>>>pF1KB6215 669 - 669 aa - 669 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6710+/-0.000428; mu= -8.4645+/- 0.027
mean_var=398.0369+/-81.577, 0's: 0 Z-trim(123.2): 66 B-trim: 808 in 1/56
Lambda= 0.064285
statistics sampled from 42655 (42723) to 42655 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.79), E-opt: 0.2 (0.501), width: 16
Scan time: 12.900
The best scores are: opt bits E(85289)
NP_002419 (OMIM: 602261) matrix metalloproteinase- ( 669) 4818 461.2 5.6e-129
XP_011526802 (OMIM: 604871) PREDICTED: matrix meta ( 556) 1331 137.7 1.1e-31
NP_005932 (OMIM: 602262) matrix metalloproteinase- ( 607) 1092 115.6 5.6e-25
XP_016883087 (OMIM: 604871) PREDICTED: matrix meta ( 614) 1073 113.8 1.9e-24
NP_006681 (OMIM: 604871) matrix metalloproteinase- ( 645) 1073 113.8 2e-24
NP_004986 (OMIM: 277950,600754) matrix metalloprot ( 582) 1071 113.6 2.1e-24
XP_016883086 (OMIM: 604871) PREDICTED: matrix meta ( 591) 1069 113.4 2.4e-24
NP_071913 (OMIM: 608482) matrix metalloproteinase- ( 562) 832 91.4 9.5e-18
XP_011520904 (OMIM: 608482) PREDICTED: matrix meta ( 528) 682 77.5 1.4e-13
XP_011520906 (OMIM: 608482) PREDICTED: matrix meta ( 478) 680 77.3 1.5e-13
NP_002412 (OMIM: 120353,226600,606963) interstitia ( 469) 652 74.7 8.8e-13
NP_001139410 (OMIM: 120353,226600,606963) intersti ( 403) 648 74.3 1e-12
NP_004762 (OMIM: 604629,612529) matrix metalloprot ( 483) 648 74.3 1.2e-12
NP_001291370 (OMIM: 120355) neutrophil collagenase ( 444) 611 70.9 1.2e-11
XP_016873260 (OMIM: 120355) PREDICTED: neutrophil ( 444) 611 70.9 1.2e-11
NP_001291371 (OMIM: 120355) neutrophil collagenase ( 444) 611 70.9 1.2e-11
XP_011541137 (OMIM: 120355) PREDICTED: neutrophil ( 444) 611 70.9 1.2e-11
NP_002415 (OMIM: 120355) neutrophil collagenase is ( 467) 611 70.9 1.2e-11
XP_011541136 (OMIM: 120355) PREDICTED: neutrophil ( 476) 611 70.9 1.2e-11
NP_002417 (OMIM: 601046) macrophage metalloelastas ( 470) 606 70.4 1.7e-11
NP_002418 (OMIM: 250400,600108,602111) collagenase ( 471) 598 69.7 2.8e-11
XP_016879050 (OMIM: 608482) PREDICTED: matrix meta ( 287) 546 64.7 5.5e-10
NP_002414 (OMIM: 178990) matrilysin preproprotein ( 267) 526 62.8 1.9e-09
NP_005931 (OMIM: 185261) stromelysin-3 preproprote ( 488) 532 63.6 2e-09
XP_016874796 (OMIM: 602285) PREDICTED: matrix meta ( 434) 515 62.0 5.6e-09
XP_011536658 (OMIM: 602285) PREDICTED: matrix meta ( 519) 515 62.0 6.3e-09
XP_011536657 (OMIM: 602285) PREDICTED: matrix meta ( 519) 515 62.0 6.3e-09
XP_011536659 (OMIM: 602285) PREDICTED: matrix meta ( 519) 515 62.0 6.3e-09
NP_057239 (OMIM: 602285) matrix metalloproteinase- ( 603) 515 62.1 7.1e-09
NP_001289438 (OMIM: 120360,259600) 72 kDa type IV ( 584) 514 62.0 7.4e-09
NP_001289437 (OMIM: 120360,259600) 72 kDa type IV ( 584) 514 62.0 7.4e-09
NP_001289439 (OMIM: 120360,259600) 72 kDa type IV ( 584) 514 62.0 7.4e-09
NP_001121363 (OMIM: 120360,259600) 72 kDa type IV ( 610) 514 62.0 7.6e-09
NP_004521 (OMIM: 120360,259600) 72 kDa type IV col ( 660) 514 62.0 8.1e-09
XP_011541138 (OMIM: 120355) PREDICTED: neutrophil ( 377) 481 58.7 4.4e-08
NP_002413 (OMIM: 185250,614466) stromelysin-1 prep ( 477) 443 55.3 6.1e-07
NP_002416 (OMIM: 185260) stromelysin-2 preproprote ( 476) 411 52.3 4.8e-06
XP_011518521 (OMIM: 605470) PREDICTED: matrix meta ( 191) 372 48.4 2.9e-05
NP_068573 (OMIM: 605470) matrix metalloproteinase- ( 261) 372 48.5 3.7e-05
NP_008914 (OMIM: 603321) matrix metalloproteinase- ( 390) 329 44.7 0.0008
XP_016858106 (OMIM: 603321) PREDICTED: matrix meta ( 468) 331 44.9 0.00081
XP_016858105 (OMIM: 603321) PREDICTED: matrix meta ( 525) 331 45.0 0.00088
XP_016858104 (OMIM: 603321) PREDICTED: matrix meta ( 526) 331 45.0 0.00088
NP_004985 (OMIM: 120361,613073) matrix metalloprot ( 707) 326 44.6 0.0015
XP_016880552 (OMIM: 608417) PREDICTED: matrix meta ( 378) 312 43.1 0.0023
XP_016880551 (OMIM: 608417) PREDICTED: matrix meta ( 378) 312 43.1 0.0023
XP_016880553 (OMIM: 608417) PREDICTED: matrix meta ( 378) 312 43.1 0.0023
XP_011523533 (OMIM: 608417) PREDICTED: matrix meta ( 390) 312 43.1 0.0024
NP_116568 (OMIM: 608417) matrix metalloproteinase- ( 393) 312 43.1 0.0024
XP_011523532 (OMIM: 608417) PREDICTED: matrix meta ( 418) 312 43.1 0.0025
>>NP_002419 (OMIM: 602261) matrix metalloproteinase-15 p (669 aa)
initn: 4818 init1: 4818 opt: 4818 Z-score: 2436.5 bits: 461.2 E(85289): 5.6e-129
Smith-Waterman score: 4818; 100.0% identity (100.0% similar) in 669 aa overlap (1-669:1-669)
10 20 30 40 50 60
pF1KB6 MGSDPSAPGRPGWTGSLLGDREEAARPRLLPLLLVLLGCLGLGVAAEDAEVHAENWLRLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGSDPSAPGRPGWTGSLLGDREEAARPRLLPLLLVLLGCLGLGVAAEDAEVHAENWLRLY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 VKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 WTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 WTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 QLYGTPDGQPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QLYGTPDGQPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 RPDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RPDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDIS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 AAYERQDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AAYERQDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFF
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 FQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 RLRMEPGYPKSILRDFMGCQEHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RLRMEPGYPKSILRDFMGCQEHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGD
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB6 FGAGVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FGAGVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLY
610 620 630 640 650 660
pF1KB6 CKRSLQEWV
:::::::::
NP_002 CKRSLQEWV
>>XP_011526802 (OMIM: 604871) PREDICTED: matrix metallop (556 aa)
initn: 1592 init1: 757 opt: 1331 Z-score: 689.8 bits: 137.7 E(85289): 1.1e-31
Smith-Waterman score: 1755; 45.7% identity (61.4% similar) in 692 aa overlap (5-669:17-556)
10 20 30 40
pF1KB6 MGSDPSAPGR-PGWTGSLLGDREEAARPRLLPLLLVLLGCL-------
: ::. : :. : .. ::: ::: : ::
XP_011 MPRSRGGRAAPGPPPPPPPPGQAPRWS------RWRVP-GRLLLLLLPALCCLPGAARAA
10 20 30 40 50
50 60 70 80
pF1KB6 ----GLG----VA-----AEDAEVH--AENWLRLYGYL-PQPSRHMSTMRSAQILASALA
: : :: :..::. ..:::. :::: : :: :...::. : ::..
XP_011 AAAAGAGNRAAVAVAVARADEAEAPFAGQNWLKSYGYLLPYDSR-ASALHSAKALQSAVS
60 70 80 90 100 110
90 100 110 120 130 140
pF1KB6 EMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNHHL
::.:::::::::::. : ::::.:::::::. . . ::: :::::::.:: ..:.
XP_011 TMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHL----SRRRRNKRYALTGQKWRQKHI
120 130 140 150 160
150 160 170 180 190 200
pF1KB6 TFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFASG
:.::.::: :.: . .:.:.:: ::...:::.:.::::..:. : ::::::..::::
XP_011 TYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDR-KEADIMIFFASG
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB6 FHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGNNLFLVAVHELGHA
:::::::::: :::::::::::::.:::::::.:::::..... ::.::::::::::::
XP_011 FHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHA
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB6 LGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPTQPLPTVTPRRP
:::::::.:.::::::::. .. :::::.:::.:::..:: : .::.::::. ::
XP_011 LGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRI
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB6 GRPDHRP-PRPPQPP-PPGGKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTVAMLRG
:..: : :.:: :: : .:: :: ::::::.:.:::..::
XP_011 HSPSERKHERQPRPPRPPLG--DRPSTPGTK-------------PNICDGNFNTVALFRG
350 360 370 380 390
390 400 410 420 430 440
pF1KB6 EMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDISAAYERQDGRFVFFKGDRYWLFR
:::::: :::::.:.::: ..::: : .::.:::. :.::::: ::::::::
XP_011 EMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKD-------
400 410 420 430 440
450 460 470 480 490 500
pF1KB6 EANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEETQRGDPGYPK
XP_011 ------------------------------------------------------------
510 520 530 540 550 560
pF1KB6 PISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMGC-QE
::::::: ::::::..: .:::::..::::.::: :.
XP_011 ----------------------YTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCNQK
450 460 470 480
570 580 590 600 610 620
pF1KB6 HVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDFGAGVNKDGGSRVVVQMEEVA
.:: : . : . :: ..: ...:
XP_011 EVE---RRKERRLP---------------QDDVD-----------------IMVTINDVP
490 500
630 640 650 660
pF1KB6 RTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLYCKRSLQEWV
.::.: :..: .: ::.: :.:.. :.. : .:. . : :: .::::
XP_011 GSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRPVQEWV
510 520 530 540 550
>>NP_005932 (OMIM: 602262) matrix metalloproteinase-16 p (607 aa)
initn: 1543 init1: 1053 opt: 1092 Z-score: 569.5 bits: 115.6 E(85289): 5.6e-25
Smith-Waterman score: 2394; 53.8% identity (76.6% similar) in 638 aa overlap (32-669:22-607)
10 20 30 40 50 60
pF1KB6 GSDPSAPGRPGWTGSLLGDREEAARPRLLPLLLVLLGCLGLGVAAEDAEVHAENWLRLYG
.: .:: : : . . ..: ::. ::
NP_005 MILLTFSTGRRLDFVHHSGVFFLQTLLWILCATVCGTEQYFNVEVWLQKYG
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 YLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRV
::: . .::..:::. . :::: ::.:::: .:: .:..: .:::.:::::::: .:
NP_005 YLPPTDPRMSVLRSAETMQSALAAMQQFYGINMTGKVDRNTIDWMKKPRCGVPDQ--TRG
60 70 80 90 100
130 140 150 160 170 180
pF1KB6 KANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQE
..... :::::::::.::...:.:.::.: : :.: .. .:.:::: ::...:::.:.:
NP_005 SSKFHIRRKRYALTGQKWQHKHITYSIKNVTPKVGDPETRKAIRRAFDVWQNVTPLTFEE
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB6 VPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPW
::: ... ....:: ..:::::::::::::: :::::::::::::.:::::::.::::
NP_005 VPYSELE-NGKRDVDITIIFASGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPW
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB6 TFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQ
:... . ::.::::::::::::::::::..:.::::::::. ..::::::.:::.:::.
NP_005 TLGNPNHDGNDLFLVAVHELGHALGLEHSNDPTAIMAPFYQYMETDNFKLPNDDLQGIQK
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB6 LYGTPDGQPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATER
.:: :: : ::.::::: :.: . : : . .: :: ::: : : : :
NP_005 IYGPPDKIPPPTRPLPTVPPHR-SIPPADPRKNDRPKPP-----RPPT-GRPSYPGAK--
290 300 310 320 330
370 380 390 400 410 420
pF1KB6 PDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDISA
::::::.:.:.:.:: :::::: .::::::.:::.:.::: : .:::::: .:.:
NP_005 -----PNICDGNFNTLAILRREMFVFKDQWFWRVRNNRVMDGYPMQITYFWRGLPPSIDA
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB6 AYERQDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFF
.:: .:: ::::::..::.:....:.::::. : . : ::: ::.::::: .:.:.::
NP_005 VYENSDGNFVFFKGNKYWVFKDTTLQPGYPHDLITLGSGIPPHGIDSAIWWEDVGKTYFF
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB6 QEDRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNER
. :::::..:: . ::::::::.::.::: ::.:::. .. ..:::::: .::::.:.
NP_005 KGDRYWRYSEEMKTMDPGYPKPITVWKGIPESPQGAFVHKENGFTYFYKGKEYWKFNNQI
460 470 480 490 500 510
550 560 570 580 590 600
pF1KB6 LRMEPGYPKSILRDFMGCQEHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDF
:..:::::.:::.:::::. :: : .. :: : :
NP_005 LKVEPGYPRSILKDFMGCD-----GPT--DRVK----------------EGHSPPDDVD-
520 530 540 550
610 620 630 640 650 660
pF1KB6 GAGVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLYC
.:......: ::... ...: .: ::.: :.:.. :..:::.:: .:::
NP_005 -----------IVIKLDNTASTVKAIAIVIPCILALCLLVLVYTVFQFKRKGTPRHILYC
560 570 580 590
pF1KB6 KRSLQEWV
:::.::::
NP_005 KRSMQEWV
600
>>XP_016883087 (OMIM: 604871) PREDICTED: matrix metallop (614 aa)
initn: 2277 init1: 1001 opt: 1073 Z-score: 559.9 bits: 113.8 E(85289): 1.9e-24
Smith-Waterman score: 2342; 55.3% identity (75.8% similar) in 620 aa overlap (54-669:51-614)
30 40 50 60 70 80
pF1KB6 AARPRLLPLLLVLLGCLGLGVAAEDAEVHAENWLRLYGYL-PQPSRHMSTMRSAQILASA
.:::. :::: : :: :...::. : ::
XP_016 QPLPSRMLKSQHFGRRRRRRRRRRLLSRVFQNWLKSYGYLLPYDSR-ASALHSAKALQSA
30 40 50 60 70
90 100 110 120 130 140
pF1KB6 LAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNH
.. ::.:::::::::::. : ::::.:::::::. . . ::: :::::::.:: ..
XP_016 VSTMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHL----SRRRRNKRYALTGQKWRQK
80 90 100 110 120 130
150 160 170 180 190 200
pF1KB6 HLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFA
:.:.::.::: :.: . .:.:.:: ::...:::.:.::::..:. : ::::::..::
XP_016 HITYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDR-KEADIMIFFA
140 150 160 170 180 190
210 220 230 240 250 260
pF1KB6 SGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGNNLFLVAVHELG
:::::::::::: :::::::::::::.:::::::.:::::..... ::.::::::::::
XP_016 SGFHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELG
200 210 220 230 240 250
270 280 290 300 310 320
pF1KB6 HALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPTQPLPTVTPR
:::::::::.:.::::::::. .. :::::.:::.:::..:: : .::.::::. :
XP_016 HALGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVR
260 270 280 290 300 310
330 340 350 360 370 380
pF1KB6 RPGRPDHRP-PRPPQPP-PPGGKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTVAML
: :..: : :.:: :: : .:: :: ::::::.:.:::..
XP_016 RIHSPSERKHERQPRPPRPPLG--DRPSTPGTK-------------PNICDGNFNTVALF
320 330 340 350
390 400 410 420 430 440
pF1KB6 RGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDISAAYERQDGRFVFFKGDRYWL
:::::::: :::::.:.::: ..::: : .::.:::. :.::::: ::::::::::.::.
XP_016 RGEMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWV
360 370 380 390 400 410
450 460 470 480 490 500
pF1KB6 FREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEETQRGDPGY
:.:...:::::. : : .: . ::::. :::.:.:.::. .::::..:: . ::::
XP_016 FKEVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGY
420 430 440 450 460 470
510 520 530 540 550
pF1KB6 PKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMGC-
::::.::.::: .:.:::.:... ::::::: ::::::..: .:::::..::::.:::
XP_016 PKPITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCN
480 490 500 510 520 530
560 570 580 590 600 610
pF1KB6 QEHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDFGAGVNKDGGSRVVVQMEE
:..:: : . : . :: ..: ...
XP_016 QKEVE---RRKERRLP---------------QDDVD-----------------IMVTIND
540 550 560
620 630 640 650 660
pF1KB6 VARTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLYCKRSLQEWV
: .::.: :..: .: ::.: :.:.. :.. : .:. . : :: .::::
XP_016 VPGSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRPVQEWV
570 580 590 600 610
>>NP_006681 (OMIM: 604871) matrix metalloproteinase-24 p (645 aa)
initn: 2132 init1: 1001 opt: 1073 Z-score: 559.6 bits: 113.8 E(85289): 2e-24
Smith-Waterman score: 2349; 52.7% identity (72.3% similar) in 692 aa overlap (5-669:17-645)
10 20 30 40
pF1KB6 MGSDPSAPGR-PGWTGSLLGDREEAARPRLLPLLLVLLGCL-------
: ::. : :. : .. ::: ::: : ::
NP_006 MPRSRGGRAAPGPPPPPPPPGQAPRWS------RWRVP-GRLLLLLLPALCCLPGAARAA
10 20 30 40 50
50 60 70 80
pF1KB6 ----GLG----VA-----AEDAEVH--AENWLRLYGYL-PQPSRHMSTMRSAQILASALA
: : :: :..::. ..:::. :::: : :: :...::. : ::..
NP_006 AAAAGAGNRAAVAVAVARADEAEAPFAGQNWLKSYGYLLPYDSR-ASALHSAKALQSAVS
60 70 80 90 100 110
90 100 110 120 130 140
pF1KB6 EMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNHHL
::.:::::::::::. : ::::.:::::::. . . ::: :::::::.:: ..:.
NP_006 TMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHL----SRRRRNKRYALTGQKWRQKHI
120 130 140 150 160
150 160 170 180 190 200
pF1KB6 TFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFASG
:.::.::: :.: . .:.:.:: ::...:::.:.::::..:. : ::::::..::::
NP_006 TYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDR-KEADIMIFFASG
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB6 FHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGNNLFLVAVHELGHA
:::::::::: :::::::::::::.:::::::.:::::..... ::.::::::::::::
NP_006 FHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHA
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB6 LGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPTQPLPTVTPRRP
:::::::.:.::::::::. .. :::::.:::.:::..:: : .::.::::. ::
NP_006 LGLEHSSDPSAIMAPFYQYMETHNFKLPQDDLQGIQKIYGPPAEPLEPTRPLPTLPVRRI
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB6 GRPDHRP-PRPPQPP-PPGGKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTVAMLRG
:..: : :.:: :: : .:: :: ::::::.:.:::..::
NP_006 HSPSERKHERQPRPPRPPLG--DRPSTPGTK-------------PNICDGNFNTVALFRG
350 360 370 380 390
390 400 410 420 430 440
pF1KB6 EMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDISAAYERQDGRFVFFKGDRYWLFR
:::::: :::::.:.::: ..::: : .::.:::. :.::::: ::::::::::.::.:.
NP_006 EMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFK
400 410 420 430 440 450
450 460 470 480 490 500
pF1KB6 EANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEETQRGDPGYPK
:...:::::. : : .: . ::::. :::.:.:.::. .::::..:: . ::::::
NP_006 EVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPK
460 470 480 490 500 510
510 520 530 540 550 560
pF1KB6 PISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMGC-QE
::.::.::: .:.:::.:... ::::::: ::::::..: .:::::..::::.::: :.
NP_006 PITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCNQK
520 530 540 550 560 570
570 580 590 600 610 620
pF1KB6 HVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDFGAGVNKDGGSRVVVQMEEVA
.:: : . : . :: ..: ...:
NP_006 EVE---RRKERRLP---------------QDDVD-----------------IMVTINDVP
580 590
630 640 650 660
pF1KB6 RTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLYCKRSLQEWV
.::.: :..: .: ::.: :.:.. :.. : .:. . : :: .::::
NP_006 GSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRPVQEWV
600 610 620 630 640
>>NP_004986 (OMIM: 277950,600754) matrix metalloproteina (582 aa)
initn: 2098 init1: 1033 opt: 1071 Z-score: 559.2 bits: 113.6 E(85289): 2.1e-24
Smith-Waterman score: 2312; 53.6% identity (73.6% similar) in 645 aa overlap (27-669:8-582)
10 20 30 40 50
pF1KB6 MGSDPSAPGRPGWTGSLLGDREEAARPR--LLPLLLVLLGCLGLGVAAEDAEVHAENWLR
:: ::::: . . .:: .:... : ::.
NP_004 MSPAPRPPRCLLLPLLTLGTALASLG-SAQSSSFSPEAWLQ
10 20 30 40
60 70 80 90 100 110
pF1KB6 LYGYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFG
::::: . . :.:: : :..:.: ::.:::. ::: : .: . :.::::::::.::
NP_004 QYGYLPPGDLRTHTQRSPQSLSAAIAAMQKFYGLQVTGKADADTMKAMRRPRCGVPDKFG
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 VRVKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLV
...:::.: :::::. : ::.....:: ::::: :.: : ..::.:.::::::.::::
NP_004 AEIKANVR--RKRYAIQGLKWQHNEITFCIQNYTPKVGEYATYEAIRKAFRVWESATPLR
110 120 130 140 150
180 190 200 210 220 230
pF1KB6 FQEVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDAD
:.:::: :: ..:.::::..:: ::::::.:::: ::::::::::::..:::::::.
NP_004 FREVPYAYIREGHEKQADIMIFFAEGFHGDSTPFDGEGGFLAHAYFPGPNIGGDTHFDSA
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB6 EPWTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRG
:::: . ::.::..::::::::::::::::::.:.::::::::: :..:: ::.:: ::
NP_004 EPWTVRNEDLNGNDIFLVAVHELGHALGLEHSSDPSAIMAPFYQWMDTENFVLPDDDRRG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB6 IQQLYGTPDGQPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRA
:::::: .: : : : .: : :. :: ::. :
NP_004 IQQLYGGESGFPTKMPPQPRTTSR-PSVPD--------------KPKNPT----------
280 290 300 310
360 370 380 390 400 410
pF1KB6 TERPDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGD
::::::::.::::::::::::::: :::::::.:.:.:.::::::.::::::..
NP_004 ------YGPNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPAS
320 330 340 350 360
420 430 440 450 460 470
pF1KB6 ISAAYERQDGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHT
:..::::.::.:::::::..:.: ::.::::::. . : :.: :.::.:..: :.:.:
NP_004 INTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKT
370 380 390 400 410 420
480 490 500 510 520 530
pF1KB6 FFFQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFD
.::. ..:.::::: . : ::: :.::.::: ::.:.:...: ..::::::.:::::.
NP_004 YFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFN
430 440 450 460 470 480
540 550 560 570 580 590
pF1KB6 NERLRMEPGYPKSILRDFMGCQEHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGD
:..:..::::::: :::.::: : :: . : .:
NP_004 NQKLKVEPGYPKSALRDWMGC-------------------PSGGRPDEGTEEETEV----
490 500 510 520
600 610 620 630 640 650
pF1KB6 GDFGAGVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVL
. :...::. .:... :..:.:::: ::.. :. ..:.:.:: :
NP_004 --IIIEVDEEGGG-----------AVSAAAVVLPVLLLLLVLAVGLAVFFFRRHGTPRRL
530 540 550 560 570
660
pF1KB6 LYCKRSLQEWV
:::.::: . :
NP_004 LYCQRSLLDKV
580
>>XP_016883086 (OMIM: 604871) PREDICTED: matrix metallop (591 aa)
initn: 2078 init1: 1001 opt: 1069 Z-score: 558.1 bits: 113.4 E(85289): 2.4e-24
Smith-Waterman score: 1942; 47.3% identity (64.9% similar) in 692 aa overlap (5-669:17-591)
10 20 30 40
pF1KB6 MGSDPSAPGR-PGWTGSLLGDREEAARPRLLPLLLVLLGCL-------
: ::. : :. : .. ::: ::: : ::
XP_016 MPRSRGGRAAPGPPPPPPPPGQAPRWS------RWRVP-GRLLLLLLPALCCLPGAARAA
10 20 30 40 50
50 60 70 80
pF1KB6 ----GLG----VA-----AEDAEVH--AENWLRLYGYL-PQPSRHMSTMRSAQILASALA
: : :: :..::. ..:::. :::: : :: :...::. : ::..
XP_016 AAAAGAGNRAAVAVAVARADEAEAPFAGQNWLKSYGYLLPYDSR-ASALHSAKALQSAVS
60 70 80 90 100 110
90 100 110 120 130 140
pF1KB6 EMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALTGRKWNNHHL
::.:::::::::::. : ::::.:::::::. . . ::: :::::::.:: ..:.
XP_016 TMQQFYGIPVTGVLDQTTIEWMKKPRCGVPDHPHL----SRRRRNKRYALTGQKWRQKHI
120 130 140 150 160
150 160 170 180 190 200
pF1KB6 TFSIQNYTEKLGWYHSMEAVRRAFRVWEQATPLVFQEVPYEDIRLRRQKEADIMVLFASG
:.::.::: :.: . .:.:.:: ::...:::.:.::::..:. : ::::::..::::
XP_016 TYSIHNYTPKVGELDTRKAIRQAFDVWQKVTPLTFEEVPYHEIKSDR-KEADIMIFFASG
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB6 FHGDSSPFDGTGGFLAHAYFPGPGLGGDTHFDADEPWTFSSTDLHGNNLFLVAVHELGHA
:::::::::: :::::::::::::.:::::::.:::::. :: : :.
XP_016 FHGDSSPFDGEGGFLAHAYFPGPGIGGDTHFDSDEPWTL------GN-----ANHD----
230 240 250 260 270
270 280 290 300 310 320
pF1KB6 LGLEHSSNPNAIMAPFYQWKDVDNFKLPEDDLRGIQQLYGTPDGQPQPTQPLPTVTPRRP
: : .::.::::. ::
XP_016 ---------------------------------------GPPAEPLEPTRPLPTLPVRRI
280 290
330 340 350 360 370 380
pF1KB6 GRPDHRP-PRPPQPP-PPGGKPERPPKPGPPVQPRATERPDQYGPNICDGDFDTVAMLRG
:..: : :.:: :: : .:: :: ::::::.:.:::..::
XP_016 HSPSERKHERQPRPPRPPLG--DRPSTPGTK-------------PNICDGNFNTVALFRG
300 310 320 330
390 400 410 420 430 440
pF1KB6 EMFVFKGRWFWRVRHNRVLDNYPMPIGHFWRGLPGDISAAYERQDGRFVFFKGDRYWLFR
:::::: :::::.:.::: ..::: : .::.:::. :.::::: ::::::::::.::.:.
XP_016 EMFVFKDRWFWRLRNNRVQEGYPMQIEQFWKGLPARIDAAYERADGRFVFFKGDKYWVFK
340 350 360 370 380 390
450 460 470 480 490 500
pF1KB6 EANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQEDRYWRFNEETQRGDPGYPK
:...:::::. : : .: . ::::. :::.:.:.::. .::::..:: . ::::::
XP_016 EVTVEPGYPHSLGELGSCLPREGIDTALRWEPVGKTYFFKGERYWRYSEERRATDPGYPK
400 410 420 430 440 450
510 520 530 540 550 560
pF1KB6 PISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLRMEPGYPKSILRDFMGC-QE
::.::.::: .:.:::.:... ::::::: ::::::..: .:::::..::::.::: :.
XP_016 PITVWKGIPQAPQGAFISKEGYYTYFYKGRDYWKFDNQKLSVEPGYPRNILRDWMGCNQK
460 470 480 490 500 510
570 580 590 600 610 620
pF1KB6 HVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDFGAGVNKDGGSRVVVQMEEVA
.:: : . : . :: ..: ...:
XP_016 EVE---RRKERRLP---------------QDDVD-----------------IMVTINDVP
520 530 540
630 640 650 660
pF1KB6 RTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLYCKRSLQEWV
.::.: :..: .: ::.: :.:.. :.. : .:. . : :: .::::
XP_016 GSVNAVAVVIPCILSLCILVLVYTIFQFKNKTGPQPVTYYKRPVQEWV
550 560 570 580 590
>>NP_071913 (OMIM: 608482) matrix metalloproteinase-25 p (562 aa)
initn: 948 init1: 261 opt: 832 Z-score: 439.6 bits: 91.4 E(85289): 9.5e-18
Smith-Waterman score: 1399; 40.9% identity (65.1% similar) in 565 aa overlap (26-576:4-521)
10 20 30 40 50
pF1KB6 MGSDPSAPGRPGWTGSLLGDREEAARPRLLPLLLVLLG--CLGLGVAAEDAEVHAENWLR
: ::: :::.::. . .:.:. . .. ::
NP_071 MRLRLRLLALLLLLLAPPARAPKPSAQDVSLGVD-WLT
10 20 30
60 70 80 90 100 110
pF1KB6 LYGYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFG
::::: : .. ..: . : .:. :::: :.: :: .: : :..:::..:: .:
NP_071 RYGYLPPPHPAQAQLQSPEKLRDAIKVMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLG
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB6 VRVKANLRRRRKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVR----RAFRVWEQA
: :.: :::.::::.: :... ::. .... .. :.:.:: :. .: .
NP_071 V---AGLVRRRRRYALSGSVWKKRTLTWRVRSFPQSSQL--SQETVRVLMSYALMAWGME
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB6 TPLVFQEVPYEDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPG-LGGDT
. :.:.:: . .: ::.. :: .:: :: :::: :: ::::.::: ..:::
NP_071 SGLTFHEVDSP-----QGQEPDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDT
160 170 180 190 200
240 250 260 270 280 290
pF1KB6 HFDADEPWTFSSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWK--DVDNFKL
::: .: :::.: : .:..:: :::::.:::::: ::: ::.:: :::: : :...:
NP_071 HFDDEETWTFGSKDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRL
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB6 PEDDLRGIQQLYGTPDGQPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPG
.:: :.::::: . : : .: : : :::
NP_071 SQDDRDGLQQLYG-----------------KAPQTPYDKPTRKPLAPPPQ----------
270 280 290 300
360 370 380 390 400 410
pF1KB6 PPVQPRATERPDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHN-RVLDNYPMPIGH
::..: :. :. :. :.:.::..: .::: : ::: ::::.. . .... : . .
NP_071 PPASP--THSPSFPIPDRCEGNFDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHR
310 320 330 340 350
420 430 440 450 460
pF1KB6 FWRGLPGDI---SAAYERQ-DGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRI
::.:::... .::: :. :::...:.: ..:.:.. .:: : .::: :: : ...
NP_071 FWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQDRQLEGG-ARPLTELGLP-PGEEV
360 370 380 390 400 410
470 480 490 500 510 520
pF1KB6 DTAIWWEPTGHTFFFQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYT
:... : .:.:.. . .:::..: . : :::::. .:.:.: : :: . .:: :. :
NP_071 DAVFSWPQNGKTYLVRGRQYWRYDEAAARPDPGYPRDLSLWEGAPPSPDDVTVSN-AGDT
420 430 440 450 460 470
530 540 550 560 570 580
pF1KB6 YFYKGTKYWKFDNERLRMEPGYPKSILRDFMGCQEHVEPGPRWPDVARPPFNPHGGAEPG
::.::..::.: .. .. :: :. . ... : ::: : :::
NP_071 YFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCPAP-SSGPRAP---RPPKATPVSETCD
480 490 500 510 520 530
590 600 610 620 630 640
pF1KB6 ADSAEGDVGDGDGDFGAGVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVLGLTYAL
NP_071 CQCELNQAAGRWPAPIPLLLLPLLVGGVASR
540 550 560
>>XP_011520904 (OMIM: 608482) PREDICTED: matrix metallop (528 aa)
initn: 831 init1: 261 opt: 682 Z-score: 364.8 bits: 77.5 E(85289): 1.4e-13
Smith-Waterman score: 1249; 41.0% identity (65.3% similar) in 490 aa overlap (99-576:44-487)
70 80 90 100 110 120
pF1KB6 HMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRR
: : :..:::..:: .:: :.: ::
XP_011 KTPRHAEACVPGAKGALKSSGERPQPRALKDPGTVATMRKPRCSLPDVLGV---AGLVRR
20 30 40 50 60 70
130 140 150 160 170 180
pF1KB6 RKRYALTGRKWNNHHLTFSIQNYTEKLGWYHSMEAVR----RAFRVWEQATPLVFQEVPY
:.::::.: :... ::. .... .. :.:.:: :. .: . . :.:.::
XP_011 RRRYALSGSVWKKRTLTWRVRSFPQSSQL--SQETVRVLMSYALMAWGMESGLTFHEVDS
80 90 100 110 120
190 200 210 220 230 240
pF1KB6 EDIRLRRQKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPG-LGGDTHFDADEPWTF
. .: ::.. :: .:: :: :::: :: ::::.::: ..:::::: .: :::
XP_011 P-----QGQEPDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTF
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB6 SSTDLHGNNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWK--DVDNFKLPEDDLRGIQQ
.: : .:..:: :::::.:::::: ::: ::.:: :::: : :...: .:: :.::
XP_011 GSKDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQ
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB6 LYGTPDGQPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATER
::: . : : .: : : ::: ::..: :.
XP_011 LYG-----------------KAPQTPYDKPTRKPLAPPPQ----------PPASP--THS
250 260 270
370 380 390 400 410
pF1KB6 PDQYGPNICDGDFDTVAMLRGEMFVFKGRWFWRVRHN-RVLDNYPMPIGHFWRGLPGDI-
:. :. :.:.::..: .::: : ::: ::::.. . .... : . .::.:::...
XP_011 PSFPIPDRCEGNFDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHRFWEGLPAQVR
280 290 300 310 320 330
420 430 440 450 460 470
pF1KB6 --SAAYERQ-DGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTG
.::: :. :::...:.: ..:.:.. .:: : .::: :: : ...:... : .:
XP_011 VVQAAYARHRDGRILLFSGPQFWVFQDRQLEGG-ARPLTELGLP-PGEEVDAVFSWPQNG
340 350 360 370 380 390
480 490 500 510 520 530
pF1KB6 HTFFFQEDRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWK
.:.. . .:::..: . : :::::. .:.:.: : :: . .:: :. :::.::..::.
XP_011 KTYLVRGRQYWRYDEAAARPDPGYPRDLSLWEGAPPSPDDVTVSN-AGDTYFFKGAHYWR
400 410 420 430 440 450
540 550 560 570 580 590
pF1KB6 FDNERLRMEPGYPKSILRDFMGCQEHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGD
: .. .. :: :. . ... : ::: : :::
XP_011 FPKNSIKTEPDAPQPMGPNWLDCPAP-SSGPRAP---RPPKATPVSETCDCQCELNQAAG
460 470 480 490 500
600 610 620 630 640 650
pF1KB6 GDGDFGAGVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPR
XP_011 RWPAPIPLLLLPLLVGGVASR
510 520
>>XP_011520906 (OMIM: 608482) PREDICTED: matrix metallop (478 aa)
initn: 831 init1: 261 opt: 680 Z-score: 364.4 bits: 77.3 E(85289): 1.5e-13
Smith-Waterman score: 1247; 41.2% identity (65.8% similar) in 483 aa overlap (106-576:1-437)
80 90 100 110 120 130
pF1KB6 AQILASALAEMQRFYGIPVTGVLDEETKEWMKRPRCGVPDQFGVRVKANLRRRRKRYALT
:..:::..:: .:: :.: :::.::::.
XP_011 MRKPRCSLPDVLGV---AGLVRRRRRYALS
10 20
140 150 160 170 180 190
pF1KB6 GRKWNNHHLTFSIQNYTEKLGWYHSMEAVR----RAFRVWEQATPLVFQEVPYEDIRLRR
: :... ::. .... .. :.:.:: :. .: . . :.:.:: .
XP_011 GSVWKKRTLTWRVRSFPQSSQL--SQETVRVLMSYALMAWGMESGLTFHEVDSP-----Q
30 40 50 60 70 80
200 210 220 230 240 250
pF1KB6 QKEADIMVLFASGFHGDSSPFDGTGGFLAHAYFPGPG-LGGDTHFDADEPWTFSSTDLHG
.: ::.. :: .:: :: :::: :: ::::.::: ..:::::: .: :::.: : .:
XP_011 GQEPDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEG
90 100 110 120 130 140
260 270 280 290 300
pF1KB6 NNLFLVAVHELGHALGLEHSSNPNAIMAPFYQWK--DVDNFKLPEDDLRGIQQLYGTPDG
..:: :::::.:::::: ::: ::.:: :::: : :...: .:: :.:::::
XP_011 TDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYG----
150 160 170 180 190
310 320 330 340 350 360
pF1KB6 QPQPTQPLPTVTPRRPGRPDHRPPRPPQPPPPGGKPERPPKPGPPVQPRATERPDQYGPN
. : : .: : : ::: ::..: :. :. :.
XP_011 -------------KAPQTPYDKPTRKPLAPPPQ----------PPASP--THSPSFPIPD
200 210 220 230
370 380 390 400 410 420
pF1KB6 ICDGDFDTVAMLRGEMFVFKGRWFWRVRHN-RVLDNYPMPIGHFWRGLPGDI---SAAYE
:.:.::..: .::: : ::: ::::.. . .... : . .::.:::... .:::
XP_011 RCEGNFDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHRFWEGLPAQVRVVQAAYA
240 250 260 270 280 290
430 440 450 460 470 480
pF1KB6 RQ-DGRFVFFKGDRYWLFREANLEPGYPQPLTSYGLGIPYDRIDTAIWWEPTGHTFFFQE
:. :::...:.: ..:.:.. .:: : .::: :: : ...:... : .:.:.. .
XP_011 RHRDGRILLFSGPQFWVFQDRQLEGG-ARPLTELGLP-PGEEVDAVFSWPQNGKTYLVRG
300 310 320 330 340
490 500 510 520 530 540
pF1KB6 DRYWRFNEETQRGDPGYPKPISVWQGIPASPKGAFLSNDAAYTYFYKGTKYWKFDNERLR
.:::..: . : :::::. .:.:.: : :: . .:: :. :::.::..::.: .. ..
XP_011 RQYWRYDEAAARPDPGYPRDLSLWEGAPPSPDDVTVSN-AGDTYFFKGAHYWRFPKNSIK
350 360 370 380 390 400
550 560 570 580 590 600
pF1KB6 MEPGYPKSILRDFMGCQEHVEPGPRWPDVARPPFNPHGGAEPGADSAEGDVGDGDGDFGA
:: :. . ... : ::: : :::
XP_011 TEPDAPQPMGPNWLDCPAP-SSGPRAP---RPPKATPVSETCDCQCELNQAAGRWPAPIP
410 420 430 440 450 460
610 620 630 640 650 660
pF1KB6 GVNKDGGSRVVVQMEEVARTVNVVMVLVPLLLLLCVLGLTYALVQMQRKGAPRVLLYCKR
XP_011 LLLLPLLVGGVASR
470
669 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:13:59 2016 done: Sat Nov 5 14:14:01 2016
Total Scan time: 12.900 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]