Result of FASTA (omim) for
pF1KB6134
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6134, 631 aa
1>>>pF1KB6134 631 - 631 aa - 631 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.6195+/-0.00062; mu= -22.4723+/- 0.038
mean_var=806.2787+/-161.638, 0's: 0 Z-trim(120.9): 53 B-trim: 0 in 0/58
Lambda= 0.045168
statistics sampled from 36636 (36690) to 36636 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.43), width: 16
Scan time: 9.460
The best scores are: opt bits E(85289)
NP_071330 (OMIM: 610094) differentially expressed ( 631) 4166 287.4 1e-76
NP_055870 (OMIM: 604762) switch-associated protein ( 585) 1712 127.5 1.3e-28
NP_001284643 (OMIM: 604762) switch-associated prot ( 527) 1086 86.7 2.3e-16
XP_005252887 (OMIM: 604762) PREDICTED: switch-asso ( 436) 1059 84.8 7e-16
>>NP_071330 (OMIM: 610094) differentially expressed in F (631 aa)
initn: 4166 init1: 4166 opt: 4166 Z-score: 1498.5 bits: 287.4 E(85289): 1e-76
Smith-Waterman score: 4166; 99.8% identity (100.0% similar) in 631 aa overlap (1-631:1-631)
10 20 30 40 50 60
pF1KB6 MALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLHIPHDPVALEEHFRDDDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLHIPHDPVALEEHFRDDDD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 GPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYRADSNGNSMLSNQDAFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYRADSNGNSMLSNQDAFR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 LWCLFNFLSEDKYPLIMVPDEVEYLLKKVLSSMSLEVSLGELEELLAQEAQVAQTTGGLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LWCLFNFLSEDKYPLIMVPDEVEYLLKKVLSSMSLEVSLGELEELLAQEAQVAQTTGGLS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 VWQFLELFNSGRCLRGVGRDTLSMAIHEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 VWQFLELFNSGRCLRGVGRDTLSMAIHEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 QPSCLCYFGSEECKEKRGIIPLDAHCCVEVLPDRDGKRCMFCVKTATRTYEMSASDTRQR
::::::::::::::::::::::::::::::::::::::::::::::.:::::::::::::
NP_071 QPSCLCYFGSEECKEKRGIIPLDAHCCVEVLPDRDGKRCMFCVKTANRTYEMSASDTRQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 QEWTAAIQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QEWTAAIQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB6 LQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKEEE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB6 AARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 AARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB6 ERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 ERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB6 KHWNVQMNRLMHPIEPGDKRPVTSSSFSGFQPPLLAHRDSSLKRLTRWGSQGNRTPSPNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 KHWNVQMNRLMHPIEPGDKRPVTSSSFSGFQPPLLAHRDSSLKRLTRWGSQGNRTPSPNS
550 560 570 580 590 600
610 620 630
pF1KB6 NEQQKSLNGGDEAPAPASTPQEDKLDPAPEN
:::::::::::::::::::::::::::::::
NP_071 NEQQKSLNGGDEAPAPASTPQEDKLDPAPEN
610 620 630
>>NP_055870 (OMIM: 604762) switch-associated protein 70 (585 aa)
initn: 1740 init1: 647 opt: 1712 Z-score: 634.6 bits: 127.5 E(85289): 1.3e-28
Smith-Waterman score: 1712; 45.6% identity (76.2% similar) in 588 aa overlap (2-583:3-579)
10 20 30 40 50
pF1KB6 MALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLHIPHDPVALEEHFRDDD
.:..::::.::.:::::: ..:::::::::::::::: :::..:::::::::::::::
NP_055 MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 DGPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYRADSNGNSMLSNQDAF
.::::.::::::::..::.::... : : .:...:::: .::: ... .....:::
NP_055 EGPVSNQGYMPYLNRFILEKVQDN-FDKIEFNRMCWTLCVKKNL---TKNPLLITEEDAF
70 80 90 100 110
120 130 140 150 160 170
pF1KB6 RLWCLFNFLSEDKYPLIMVPDEVEYLLKKVLSSMSLEVSLGELEELLAQEAQVAQTTGGL
..: .::::::::::::.: .:.::::::. .:. . . :.. . . .. .::
NP_055 KIWVIFNFLSEDKYPLIIVSEEIEYLLKKLTEAMG---GGWQQEQFEHYKINFDDSKNGL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 SVWQFLELFNSGRCLRGVGRDTLSMAIHEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQ
:.:...::...:. .:. :.:.::::.::..::: :::::::. :.:: :.::.::::
NP_055 SAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 LQPSCLCYFGSEECKEKRGIIPLDAHCCVEVLPDRDGKRCMFCVKTATRTYEMSASDTRQ
:.:. . :. ::. :.:.: : :: .:::: :::.:::.:.: :: .:.:.:::: ..
NP_055 LKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 RQEWTAAIQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLR-LQQLQEEKE
.::: ::. .:.: :. ::. .:.:.: : ... :..::: : ...:: .:
NP_055 KQEWIQAIHSTIHLLKLGSPPPHKEARQRRKELR----KKQLAEQEELERQMKELQAANE
300 310 320 330 340
360 370 380 390 400 410
pF1KB6 RKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKE
: :::: ... ..: :::..: . . ::: . .:.. . : .:. .. :
NP_055 SKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKS
350 360 370 380 390 400
420 430 440 450 460 470
pF1KB6 EEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKE
: . ::..:::.: .:::::. : .::.:::.:: :.:::::: : .: . .
NP_055 SELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHL
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB6 EQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQAST
::.. :. .. ::.::... . . ..::.:..:::... .:..: :. : ...::..:..
NP_055 EQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLEQLELERKQALEQYEEVKKKLEMATN
470 480 490 500 510 520
540 550 560 570 580 590
pF1KB6 NVKHWNVQMNR---LMHPIEPGDKRP--VTSSSFSGFQPPLLAHRDSSLKRLTRWGSQGN
..: :. .. . :.. ::::.: : .:. . ..: : .:... :
NP_055 KTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE
530 540 550 560 570 580
600 610 620 630
pF1KB6 RTPSPNSNEQQKSLNGGDEAPAPASTPQEDKLDPAPEN
>>NP_001284643 (OMIM: 604762) switch-associated protein (527 aa)
initn: 1615 init1: 647 opt: 1086 Z-score: 414.7 bits: 86.7 E(85289): 2.3e-16
Smith-Waterman score: 1380; 40.6% identity (67.7% similar) in 588 aa overlap (2-583:3-521)
10 20 30 40 50
pF1KB6 MALRKELLKSIWYAFTALDVEKSGKVSKSQLKVLSHNLYTVLHIPHDPVALEEHFRDDD
.:..::::.::.:::::: ..:::::::::::::::: :::..:::::::::::::::
NP_001 MGSLKEELLKAIWHAFTALDQDHSGKVSKSQLKVLSHNLCTVLKVPHDPVALEEHFRDDD
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 DGPVSSQGYMPYLNKYILDKVEEGAFVKEHFDELCWTLTAKKNYRADSNGNSMLSNQDAF
.::::.::::::::..::.:.:
NP_001 EGPVSNQGYMPYLNRFILEKIE--------------------------------------
70 80
120 130 140 150 160 170
pF1KB6 RLWCLFNFLSEDKYPLIMVPDEVEYLLKKVLSSMSLEVSLGELEELLAQEAQVAQTTGGL
:::::. .:. . . :.. . . .. .::
NP_001 ------------------------YLLKKLTEAMG---GGWQQEQFEHYKINFDDSKNGL
90 100 110
180 190 200 210 220 230
pF1KB6 SVWQFLELFNSGRCLRGVGRDTLSMAIHEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQ
:.:...::...:. .:. :.:.::::.::..::: :::::::. :.:: :.::.::::
NP_001 SAWELIELIGNGQFSKGMDRQTVSMAINEVFNELILDVLKQGYMMKKGHRRKNWTERWFV
120 130 140 150 160 170
240 250 260 270 280 290
pF1KB6 LQPSCLCYFGSEECKEKRGIIPLDAHCCVEVLPDRDGKRCMFCVKTATRTYEMSASDTRQ
:.:. . :. ::. :.:.: : :: .:::: :::.:::.:.: :: .:.:.:::: ..
NP_001 LKPNIISYYVSEDLKDKKGDILLDENCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKK
180 190 200 210 220 230
300 310 320 330 340 350
pF1KB6 RQEWTAAIQMAIRLQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLR-LQQLQEEKE
.::: ::. .:.: :. ::. .:.:.: : ... :..::: : ...:: .:
NP_001 KQEWIQAIHSTIHLLKLGSPPPHKEARQRRKELR----KKQLAEQEELERQMKELQAANE
240 250 260 270 280 290
360 370 380 390 400 410
pF1KB6 RKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKE
: :::: ... ..: :::..: . . ::: . .:.. . : .:. .. :
NP_001 SKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQARFSTELEREKLIRQQMEEQVAQKS
300 310 320 330 340 350
420 430 440 450 460 470
pF1KB6 EEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKE
: . ::..:::.: .:::::. : .::.:::.:: :.:::::: : .: . .
NP_001 SELEQYLQRVRELEDMYLKLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHL
360 370 380 390 400 410
480 490 500 510 520 530
pF1KB6 EQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQAST
::.. :. .. ::.::... . . ..::.:..:::... .:..: :. : ...::..:..
NP_001 EQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLEQLELERKQALEQYEEVKKKLEMATN
420 430 440 450 460 470
540 550 560 570 580 590
pF1KB6 NVKHWNVQMNR---LMHPIEPGDKRP--VTSSSFSGFQPPLLAHRDSSLKRLTRWGSQGN
..: :. .. . :.. ::::.: : .:. . ..: : .:... :
NP_001 KTKSWKDKVAHHEGLIRLIEPGSKNPHLITNWGPAAFTEAELEEREKNWKEKKTTE
480 490 500 510 520
600 610 620 630
pF1KB6 RTPSPNSNEQQKSLNGGDEAPAPASTPQEDKLDPAPEN
>>XP_005252887 (OMIM: 604762) PREDICTED: switch-associat (436 aa)
initn: 1232 init1: 647 opt: 1059 Z-score: 406.2 bits: 84.8 E(85289): 7e-16
Smith-Waterman score: 1059; 40.7% identity (73.0% similar) in 415 aa overlap (175-583:20-430)
150 160 170 180 190 200
pF1KB6 LLKKVLSSMSLEVSLGELEELLAQEAQVAQTTGGLSVWQFLELFNSGRCLRGVGRDTLSM
. .:::.:...::...:. .:. :.:.::
XP_005 MGGGWQQEQFEHYKINFDDSKNGLSAWELIELIGNGQFSKGMDRQTVSM
10 20 30 40
210 220 230 240 250 260
pF1KB6 AIHEVYQELIQDVLKQGYLWKRGHLRRNWAERWFQLQPSCLCYFGSEECKEKRGIIPLDA
::.::..::: :::::::. :.:: :.::.:::: :.:. . :. ::. :.:.: : ::
XP_005 AINEVFNELILDVLKQGYMMKKGHRRKNWTERWFVLKPNIISYYVSEDLKDKKGDILLDE
50 60 70 80 90 100
270 280 290 300 310 320
pF1KB6 HCCVEVLPDRDGKRCMFCVKTATRTYEMSASDTRQRQEWTAAIQMAIRLQAEGKTSLHKD
.:::: :::.:::.:.: :: .:.:.:::: ...::: ::. .:.: :. ::.
XP_005 NCCVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEWIQAIHSTIHLLKLGSPPPHKE
110 120 130 140 150 160
330 340 350 360 370 380
pF1KB6 LKQKRREQREQRERRRAAKEEELLR-LQQLQEEKERKLQELELLQEAQRQAERLLQEEEE
.:.:.: : ... :..::: : ...:: .: : :::: ... ..: :::.
XP_005 ARQRRKELR----KKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEK
170 180 190 200 210 220
390 400 410 420 430 440
pF1KB6 RRRSQHRELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQ
.: . . ::: . .:.. . : .:. .. : : . ::..:::.: .:::::.
XP_005 KRLQTQVELQARFSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALE
230 240 250 260 270 280
450 460 470 480 490 500
pF1KB6 LEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSR
: .::.:::.:: :.:::::: : .: . . ::.. :. .. ::.::... . . .
XP_005 DERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELENQRVLKEQ
290 300 310 320 330 340
510 520 530 540 550 560
pF1KB6 SLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKHWNVQMNR---LMHPIEPGDKR
.::.:..:::... .:..: :. : ...::..:....: :. .. . :.. ::::.:
XP_005 ALQEAMEQLEQLELERKQALEQYEEVKKKLEMATNKTKSWKDKVAHHEGLIRLIEPGSKN
350 360 370 380 390 400
570 580 590 600 610
pF1KB6 P--VTSSSFSGFQPPLLAHRDSSLKRLTRWGSQGNRTPSPNSNEQQKSLNGGDEAPAPAS
: .:. . ..: : .:... :
XP_005 PHLITNWGPAAFTEAELEEREKNWKEKKTTE
410 420 430
631 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 11:00:47 2016 done: Sat Nov 5 11:00:48 2016
Total Scan time: 9.460 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]