FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6128, 627 aa
  1>>>pF1KB6128 627 - 627 aa - 627 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 8.8165+/-0.000468; mu= 3.1245+/- 0.029
 mean_var=231.1353+/-47.388, 0's: 0 Z-trim(116.7): 132  B-trim: 322 in 2/55
 Lambda= 0.084361
 statistics sampled from 27882 (28056) to 27882 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.675), E-opt: 0.2 (0.329), width:  16
 Scan time: 11.420

The best scores are:                                      opt bits E(85289)
NP_054727 (OMIM: 300859,300963) coiled-coil domain ( 627) 4057 507.5 5.7e-143
XP_005272656 (OMIM: 300859,300963) PREDICTED: coil ( 626) 4037 505.1 3.1e-142


>>NP_054727 (OMIM: 300859,300963) coiled-coil domain-con  (627 aa)
 initn: 4057 init1: 4057 opt: 4057  Z-score: 2687.8  bits: 507.5 E(85289): 5.7e-143
Smith-Waterman score: 4057; 100.0% identity (100.0% similar) in 627 aa overlap (1-627:1-627)

               10        20        30        40        50        60
pF1KB6 MEEADRILIHSLRQAGTAVPPDVQTLRAFTTELVVEAVVRCLRVINPAVGSGLSPLLPLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MEEADRILIHSLRQAGTAVPPDVQTLRAFTTELVVEAVVRCLRVINPAVGSGLSPLLPLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 MSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDADQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 MSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDADQPA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 GDSAILLRAIGSQIRDQLALPWVPPHLRTPKLQHLQGSALQKPFHASRLVVPELSSRGEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 GDSAILLRAIGSQIRDQLALPWVPPHLRTPKLQHLQGSALQKPFHASRLVVPELSSRGEP
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 REFQASPLLLPVPTQVPQPVGRVASLLEHHALQLCQQTGRDRPGDEDWVHRTSRLPPQED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 REFQASPLLLPVPTQVPQPVGRVASLLEHHALQLCQQTGRDRPGDEDWVHRTSRLPPQED
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 TRAQRQRLQKQLTEHLRQSWGLLGAPIQARDLGELLQAWGAGAKTGAPKGSRFTHSEKFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 TRAQRQRLQKQLTEHLRQSWGLLGAPIQARDLGELLQAWGAGAKTGAPKGSRFTHSEKFT
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 FHLEPQAQATQVSDVPATSRRPEQVTWAAQEQELESLREQLEGVNRSIEEVEADMKTLGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 FHLEPQAQATQVSDVPATSRRPEQVTWAAQEQELESLREQLEGVNRSIEEVEADMKTLGV
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB6 SFVQAESECRHSKLSTAEREQALRLKSRAVELLPDGTANLAKLQLVVENSAQRVIHLAGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 SFVQAESECRHSKLSTAEREQALRLKSRAVELLPDGTANLAKLQLVVENSAQRVIHLAGQ
              370       380       390       400       410       420

              430       440       450       460       470       480
pF1KB6 WEKHRVPLLAEYRHLRKLQDCRELESSRRLAEIQELHQSVRAAAEEARRKEEVYKQLMSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 WEKHRVPLLAEYRHLRKLQDCRELESSRRLAEIQELHQSVRAAAEEARRKEEVYKQLMSE
              430       440       450       460       470       480

              490       500       510       520       530       540
pF1KB6 LETLPRDVSRLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 LETLPRDVSRLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTD
              490       500       510       520       530       540

              550       560       570       580       590       600
pF1KB6 ELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETELGKKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_054 ELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETELGKKTL
              550       560       570       580       590       600

              610       620       
pF1KB6 SNLEKIREDYRALRQENAGLLGRVREA
       :::::::::::::::::::::::::::
NP_054 SNLEKIREDYRALRQENAGLLGRVREA
              610       620       

>>XP_005272656 (OMIM: 300859,300963) PREDICTED: coiled-c  (626 aa)
 initn: 2890 init1: 2890 opt: 4037  Z-score: 2674.6  bits: 505.1 E(85289): 3.1e-142
Smith-Waterman score: 4037; 99.8% identity (99.8% similar) in 627 aa overlap (1-627:1-626)

               10        20        30        40        50        60
pF1KB6 MEEADRILIHSLRQAGTAVPPDVQTLRAFTTELVVEAVVRCLRVINPAVGSGLSPLLPLA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MEEADRILIHSLRQAGTAVPPDVQTLRAFTTELVVEAVVRCLRVINPAVGSGLSPLLPLA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 MSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDADQPA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MSARFRLAMSLAQACMDLGYPLELGYQNFLYPSEPDLRDLLLFLAERLPTDASEDADQPA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 GDSAILLRAIGSQIRDQLALPWVPPHLRTPKLQHLQGSALQKPFHASRLVVPELSSRGEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: ::
XP_005 GDSAILLRAIGSQIRDQLALPWVPPHLRTPKLQHLQGSALQKPFHASRLVVPELSSR-EP
              130       140       150       160       170          

              190       200       210       220       230       240
pF1KB6 REFQASPLLLPVPTQVPQPVGRVASLLEHHALQLCQQTGRDRPGDEDWVHRTSRLPPQED
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 REFQASPLLLPVPTQVPQPVGRVASLLEHHALQLCQQTGRDRPGDEDWVHRTSRLPPQED
     180       190       200       210       220       230         

              250       260       270       280       290       300
pF1KB6 TRAQRQRLQKQLTEHLRQSWGLLGAPIQARDLGELLQAWGAGAKTGAPKGSRFTHSEKFT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRAQRQRLQKQLTEHLRQSWGLLGAPIQARDLGELLQAWGAGAKTGAPKGSRFTHSEKFT
     240       250       260       270       280       290         

              310       320       330       340       350       360
pF1KB6 FHLEPQAQATQVSDVPATSRRPEQVTWAAQEQELESLREQLEGVNRSIEEVEADMKTLGV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FHLEPQAQATQVSDVPATSRRPEQVTWAAQEQELESLREQLEGVNRSIEEVEADMKTLGV
     300       310       320       330       340       350         

              370       380       390       400       410       420
pF1KB6 SFVQAESECRHSKLSTAEREQALRLKSRAVELLPDGTANLAKLQLVVENSAQRVIHLAGQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFVQAESECRHSKLSTAEREQALRLKSRAVELLPDGTANLAKLQLVVENSAQRVIHLAGQ
     360       370       380       390       400       410         

              430       440       450       460       470       480
pF1KB6 WEKHRVPLLAEYRHLRKLQDCRELESSRRLAEIQELHQSVRAAAEEARRKEEVYKQLMSE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WEKHRVPLLAEYRHLRKLQDCRELESSRRLAEIQELHQSVRAAAEEARRKEEVYKQLMSE
     420       430       440       450       460       470         

              490       500       510       520       530       540
pF1KB6 LETLPRDVSRLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LETLPRDVSRLAYTQRILEIVGNIRKQKEEITKILSDTKELQKEINSLSGKLDRTFAVTD
     480       490       500       510       520       530         

              550       560       570       580       590       600
pF1KB6 ELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETELGKKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ELVFKDAKKDDAVRKAYKYLAALHENCSQLIQTIEDTGTIMREVRDLEEQIETELGKKTL
     540       550       560       570       580       590         

              610       620       
pF1KB6 SNLEKIREDYRALRQENAGLLGRVREA
       :::::::::::::::::::::::::::
XP_005 SNLEKIREDYRALRQENAGLLGRVREA
     600       610       620      




627 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 10:08:23 2016 done: Sat Nov  5 10:08:25 2016
 Total Scan time: 11.420 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]