Result of FASTA (omim) for
pF1KB5988
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5988, 558 aa
1>>>pF1KB5988 558 - 558 aa - 558 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4553+/-0.000532; mu= 12.2579+/- 0.033
mean_var=78.7530+/-15.903, 0's: 0 Z-trim(107.2): 152 B-trim: 0 in 0/50
Lambda= 0.144524
statistics sampled from 15114 (15267) to 15114 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.516), E-opt: 0.2 (0.179), width: 16
Scan time: 10.300
The best scores are: opt bits E(85289)
NP_001093899 (OMIM: 179502) rap1 GTPase-GDP dissoc ( 558) 3494 739.0 9.1e-213
NP_001093898 (OMIM: 179502) rap1 GTPase-GDP dissoc ( 559) 3487 737.5 2.5e-212
NP_001093897 (OMIM: 179502) rap1 GTPase-GDP dissoc ( 607) 2737 581.2 3.2e-165
NP_001093896 (OMIM: 179502) rap1 GTPase-GDP dissoc ( 608) 2737 581.2 3.2e-165
NP_066982 (OMIM: 179502) rap1 GTPase-GDP dissociat ( 607) 2720 577.6 3.8e-164
NP_001093900 (OMIM: 179502) rap1 GTPase-GDP dissoc ( 516) 2485 528.6 1.8e-149
XP_016866329 (OMIM: 604545) PREDICTED: importin su ( 536) 196 51.4 8.8e-06
NP_002260 (OMIM: 604545) importin subunit alpha-6 ( 539) 196 51.4 8.9e-06
XP_016866328 (OMIM: 604545) PREDICTED: importin su ( 539) 196 51.4 8.9e-06
XP_011534107 (OMIM: 604545) PREDICTED: importin su ( 559) 196 51.4 9.2e-06
XP_016866327 (OMIM: 604545) PREDICTED: importin su ( 559) 196 51.4 9.2e-06
NP_001307540 (OMIM: 600685) importin subunit alpha ( 529) 180 48.0 8.8e-05
NP_002257 (OMIM: 600685) importin subunit alpha-1 ( 529) 180 48.0 8.8e-05
XP_016871321 (OMIM: 611226) PREDICTED: armadillo r ( 681) 178 47.6 0.00015
XP_011517652 (OMIM: 611226) PREDICTED: armadillo r ( 682) 178 47.6 0.00015
NP_001269675 (OMIM: 611226) armadillo repeat-conta ( 688) 178 47.6 0.00015
NP_001269674 (OMIM: 611226) armadillo repeat-conta ( 865) 178 47.7 0.00019
NP_775104 (OMIM: 611226) armadillo repeat-containi ( 872) 178 47.7 0.00019
XP_005252438 (OMIM: 611226) PREDICTED: armadillo r ( 784) 171 46.2 0.00047
NP_036448 (OMIM: 610563) importin subunit alpha-7 ( 536) 157 43.2 0.0025
XP_005270768 (OMIM: 610563) PREDICTED: importin su ( 566) 157 43.2 0.0026
XP_016867705 (OMIM: 614107) PREDICTED: importin su ( 425) 148 41.3 0.0073
XP_016867704 (OMIM: 614107) PREDICTED: importin su ( 487) 148 41.3 0.0083
NP_001139187 (OMIM: 614107) importin subunit alpha ( 516) 148 41.3 0.0088
XP_016867703 (OMIM: 614107) PREDICTED: importin su ( 521) 148 41.3 0.0089
XP_016867701 (OMIM: 614107) PREDICTED: importin su ( 521) 148 41.3 0.0089
XP_016867702 (OMIM: 614107) PREDICTED: importin su ( 521) 148 41.3 0.0089
XP_016867700 (OMIM: 614107) PREDICTED: importin su ( 522) 148 41.3 0.0089
XP_016867699 (OMIM: 614107) PREDICTED: importin su ( 537) 148 41.3 0.0091
XP_011514517 (OMIM: 614107) PREDICTED: importin su ( 543) 148 41.4 0.0092
XP_016867697 (OMIM: 614107) PREDICTED: importin su ( 548) 148 41.4 0.0093
>>NP_001093899 (OMIM: 179502) rap1 GTPase-GDP dissociati (558 aa)
initn: 3494 init1: 3494 opt: 3494 Z-score: 3940.8 bits: 739.0 E(85289): 9.1e-213
Smith-Waterman score: 3494; 100.0% identity (100.0% similar) in 558 aa overlap (1-558:1-558)
10 20 30 40 50 60
pF1KB5 MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 HSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDAN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 CIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 FLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 ESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHEN
490 500 510 520 530 540
550
pF1KB5 KSVAQQASLTEQRLTVES
::::::::::::::::::
NP_001 KSVAQQASLTEQRLTVES
550
>>NP_001093898 (OMIM: 179502) rap1 GTPase-GDP dissociati (559 aa)
initn: 3487 init1: 3487 opt: 3487 Z-score: 3932.9 bits: 737.5 E(85289): 2.5e-212
Smith-Waterman score: 3487; 100.0% identity (100.0% similar) in 557 aa overlap (2-558:3-559)
10 20 30 40 50
pF1KB5 MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 SHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEEL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 VKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 LKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDA
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 NCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVL
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 KFLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 LLSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKD
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB5 LESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHE
490 500 510 520 530 540
540 550
pF1KB5 NKSVAQQASLTEQRLTVES
:::::::::::::::::::
NP_001 NKSVAQQASLTEQRLTVES
550
>>NP_001093897 (OMIM: 179502) rap1 GTPase-GDP dissociati (607 aa)
initn: 2734 init1: 2734 opt: 2737 Z-score: 3087.2 bits: 581.2 E(85289): 3.2e-165
Smith-Waterman score: 3285; 91.7% identity (91.7% similar) in 590 aa overlap (18-558:18-607)
10 20 30 40 50 60
pF1KB5 MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP
:::::::::::::::::::::::::::::::::::::::::::
NP_001 MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 QSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDS
70 80 90 100 110 120
130
pF1KB5 H-------------------------------------------------SLQAQLINMG
: ::::::::::
NP_001 HEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINMG
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB5 VIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDK
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB5 REMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLLL
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB5 LGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIVE
310 320 330 340 350 360
320 330 340 350 360 370
pF1KB5 KLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQF
370 380 390 400 410 420
380 390 400 410 420 430
pF1KB5 KLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKSK
430 440 450 460 470 480
440 450 460 470 480 490
pF1KB5 DVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHR
490 500 510 520 530 540
500 510 520 530 540 550
pF1KB5 LLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLTE
550 560 570 580 590 600
pF1KB5 QRLTVES
:::::::
NP_001 QRLTVES
>>NP_001093896 (OMIM: 179502) rap1 GTPase-GDP dissociati (608 aa)
initn: 2734 init1: 2734 opt: 2737 Z-score: 3087.2 bits: 581.2 E(85289): 3.2e-165
Smith-Waterman score: 3285; 91.7% identity (91.7% similar) in 590 aa overlap (18-558:19-608)
10 20 30 40 50
pF1KB5 MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT
::::::::::::::::::::::::::::::::::::::::::
NP_001 MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD
70 80 90 100 110 120
120 130
pF1KB5 SH-------------------------------------------------SLQAQLINM
:: :::::::::
NP_001 SHEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINM
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB5 GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB5 KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB5 LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV
310 320 330 340 350 360
320 330 340 350 360 370
pF1KB5 EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ
370 380 390 400 410 420
380 390 400 410 420 430
pF1KB5 FKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS
430 440 450 460 470 480
440 450 460 470 480 490
pF1KB5 KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH
490 500 510 520 530 540
500 510 520 530 540 550
pF1KB5 RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT
550 560 570 580 590 600
pF1KB5 EQRLTVES
::::::::
NP_001 EQRLTVES
>>NP_066982 (OMIM: 179502) rap1 GTPase-GDP dissociation (607 aa)
initn: 2484 init1: 1661 opt: 2720 Z-score: 3068.0 bits: 577.6 E(85289): 3.8e-164
Smith-Waterman score: 3268; 91.5% identity (91.5% similar) in 590 aa overlap (18-558:19-607)
10 20 30 40 50
pF1KB5 MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT
::::::::::::::::::::::::::::::::::::::::::
NP_066 MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD
70 80 90 100 110 120
120 130
pF1KB5 SH-------------------------------------------------SLQAQLINM
:: :::::::::
NP_066 SHEGRSAVDQAGGAQIVIDHLRSLCSITDPANEKLLTVFCGMLMNYSNENDSLQAQLINM
130 140 150 160 170 180
140 150 160 170 180 190
pF1KB5 GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 GVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQIEHD
190 200 210 220 230 240
200 210 220 230 240 250
pF1KB5 KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 KREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITELKTGSDLMVLL
250 260 270 280 290 300
260 270 280 290 300 310
pF1KB5 LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 LLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVDNGIV
310 320 330 340 350 360
320 330 340 350 360 370
pF1KB5 EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 EKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKSEMPPVQ
370 380 390 400 410 420
380 390 400 410 420 430
pF1KB5 FKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
NP_066 FKLLGTLRMLIDAQ-EAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHSKS
430 440 450 460 470
440 450 460 470 480 490
pF1KB5 KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 KDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKDLESAKLVQILH
480 490 500 510 520 530
500 510 520 530 540 550
pF1KB5 RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHENKSVAQQASLT
540 550 560 570 580 590
pF1KB5 EQRLTVES
::::::::
NP_066 EQRLTVES
600
>>NP_001093900 (OMIM: 179502) rap1 GTPase-GDP dissociati (516 aa)
initn: 2456 init1: 2456 opt: 2485 Z-score: 2804.4 bits: 528.6 E(85289): 1.8e-149
Smith-Waterman score: 3110; 92.1% identity (92.3% similar) in 557 aa overlap (2-558:3-516)
10 20 30 40 50
pF1KB5 MDNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MADNLSDTLKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQSSCKAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 SHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEEL
: .:::::::::::::::
NP_001 S-------------------------------------------QSSKEQFASTNIAEEL
130
180 190 200 210 220 230
pF1KB5 VKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSDKEDDITE
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB5 LKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDA
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB5 NCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVL
260 270 280 290 300 310
360 370 380 390 400 410
pF1KB5 KFLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNR
320 330 340 350 360 370
420 430 440 450 460 470
pF1KB5 LLSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLSALIRHSKSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELGTAEKD
380 390 400 410 420 430
480 490 500 510 520 530
pF1KB5 LESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LESAKLVQILHRLLADERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDVVSKLRSHE
440 450 460 470 480 490
540 550
pF1KB5 NKSVAQQASLTEQRLTVES
:::::::::::::::::::
NP_001 NKSVAQQASLTEQRLTVES
500 510
>>XP_016866329 (OMIM: 604545) PREDICTED: importin subuni (536 aa)
initn: 153 init1: 107 opt: 196 Z-score: 224.8 bits: 51.4 E(85289): 8.8e-06
Smith-Waterman score: 196; 22.2% identity (60.3% similar) in 252 aa overlap (38-279:113-362)
10 20 30 40 50 60
pF1KB5 LKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQSSC--K
: .. :: :..: :...: . .: .
XP_016 TDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQ
90 100 110 120 130 140
70 80 90 100 110 120
pF1KB5 AKVANIIAEVAKNEFMRIPCV-DAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQ
..: ....:.. :.. : ..: . ...::::. ..: :. ::::: :. .
XP_016 FEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECR
150 160 170 180 190 200
130 140 150 160 170 180
pF1KB5 AQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFK
..: ..: :..:: . . . :. . :..:: . .. .:.... .... .
XP_016 DFVLNCEILPPLLELL-TNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLL
210 220 230 240 250 260
190 200 210 220 230 240
pF1KB5 KQIEHDKREMIFEVLAPLAENDAIKLQ-LVEAGLVECLLEIVQQ---KVDSDKEDDITEL
. . : . .:. :... :.: ....:. . :.:.... :: : . ..
XP_016 FSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNI
270 280 290 300 310 320
250 260 270 280 290
pF1KB5 KTGSDLMVLLLLGDESMQ---KLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARN
::.:... ..:. .. .:. . : :. .. : ::
XP_016 VTGDDIQTQVILNCSALPCLLHLLSSPKESI-RKEACWTVSNITAGNRAQIQAVIDANIF
330 340 350 360 370 380
300 310 320 330 340 350
pF1KB5 DANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEA
XP_016 PVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQV
390 400 410 420 430 440
>>NP_002260 (OMIM: 604545) importin subunit alpha-6 [Hom (539 aa)
initn: 153 init1: 107 opt: 196 Z-score: 224.7 bits: 51.4 E(85289): 8.9e-06
Smith-Waterman score: 196; 22.2% identity (60.3% similar) in 252 aa overlap (38-279:116-365)
10 20 30 40 50 60
pF1KB5 LKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQSSC--K
: .. :: :..: :...: . .: .
NP_002 TDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQ
90 100 110 120 130 140
70 80 90 100 110 120
pF1KB5 AKVANIIAEVAKNEFMRIPCV-DAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQ
..: ....:.. :.. : ..: . ...::::. ..: :. ::::: :. .
NP_002 FEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECR
150 160 170 180 190 200
130 140 150 160 170 180
pF1KB5 AQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFK
..: ..: :..:: . . . :. . :..:: . .. .:.... .... .
NP_002 DFVLNCEILPPLLELL-TNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLL
210 220 230 240 250 260
190 200 210 220 230 240
pF1KB5 KQIEHDKREMIFEVLAPLAENDAIKLQ-LVEAGLVECLLEIVQQ---KVDSDKEDDITEL
. . : . .:. :... :.: ....:. . :.:.... :: : . ..
NP_002 FSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNI
270 280 290 300 310 320
250 260 270 280 290
pF1KB5 KTGSDLMVLLLLGDESMQ---KLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARN
::.:... ..:. .. .:. . : :. .. : ::
NP_002 VTGDDIQTQVILNCSALPCLLHLLSSPKESI-RKEACWTVSNITAGNRAQIQAVIDANIF
330 340 350 360 370 380
300 310 320 330 340 350
pF1KB5 DANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEA
NP_002 PVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQV
390 400 410 420 430 440
>>XP_016866328 (OMIM: 604545) PREDICTED: importin subuni (539 aa)
initn: 153 init1: 107 opt: 196 Z-score: 224.7 bits: 51.4 E(85289): 8.9e-06
Smith-Waterman score: 196; 22.2% identity (60.3% similar) in 252 aa overlap (38-279:116-365)
10 20 30 40 50 60
pF1KB5 LKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQSSC--K
: .. :: :..: :...: . .: .
XP_016 TDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQ
90 100 110 120 130 140
70 80 90 100 110 120
pF1KB5 AKVANIIAEVAKNEFMRIPCV-DAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQ
..: ....:.. :.. : ..: . ...::::. ..: :. ::::: :. .
XP_016 FEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECR
150 160 170 180 190 200
130 140 150 160 170 180
pF1KB5 AQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFK
..: ..: :..:: . . . :. . :..:: . .. .:.... .... .
XP_016 DFVLNCEILPPLLELL-TNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLL
210 220 230 240 250 260
190 200 210 220 230 240
pF1KB5 KQIEHDKREMIFEVLAPLAENDAIKLQ-LVEAGLVECLLEIVQQ---KVDSDKEDDITEL
. . : . .:. :... :.: ....:. . :.:.... :: : . ..
XP_016 FSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNI
270 280 290 300 310 320
250 260 270 280 290
pF1KB5 KTGSDLMVLLLLGDESMQ---KLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARN
::.:... ..:. .. .:. . : :. .. : ::
XP_016 VTGDDIQTQVILNCSALPCLLHLLSSPKESI-RKEACWTVSNITAGNRAQIQAVIDANIF
330 340 350 360 370 380
300 310 320 330 340 350
pF1KB5 DANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEA
XP_016 PVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQV
390 400 410 420 430 440
>>XP_011534107 (OMIM: 604545) PREDICTED: importin subuni (559 aa)
initn: 153 init1: 107 opt: 196 Z-score: 224.4 bits: 51.4 E(85289): 9.2e-06
Smith-Waterman score: 196; 22.2% identity (60.3% similar) in 252 aa overlap (38-279:136-385)
10 20 30 40 50 60
pF1KB5 LKKLKITAVDKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLTPQSSC--K
: .. :: :..: :...: . .: .
XP_011 TDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFLERNENCTLQ
110 120 130 140 150 160
70 80 90 100 110 120
pF1KB5 AKVANIIAEVAKNEFMRIPCV-DAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQ
..: ....:.. :.. : ..: . ...::::. ..: :. ::::: :. .
XP_011 FEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGNIAGDNAECR
170 180 190 200 210 220
130 140 150 160 170 180
pF1KB5 AQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFK
..: ..: :..:: . . . :. . :..:: . .. .:.... .... .
XP_011 DFVLNCEILPPLLELL-TNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLL
230 240 250 260 270 280
190 200 210 220 230 240
pF1KB5 KQIEHDKREMIFEVLAPLAENDAIKLQ-LVEAGLVECLLEIVQQ---KVDSDKEDDITEL
. . : . .:. :... :.: ....:. . :.:.... :: : . ..
XP_011 FSSDPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNI
290 300 310 320 330 340
250 260 270 280 290
pF1KB5 KTGSDLMVLLLLGDESMQ---KLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARN
::.:... ..:. .. .:. . : :. .. : ::
XP_011 VTGDDIQTQVILNCSALPCLLHLLSSPKESI-RKEACWTVSNITAGNRAQIQAVIDANIF
350 360 370 380 390 400
300 310 320 330 340 350
pF1KB5 DANCIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEA
XP_011 PVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQV
410 420 430 440 450 460
558 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:44:41 2016 done: Fri Nov 4 21:44:42 2016
Total Scan time: 10.300 Total Display time: 0.090
Function used was FASTA [36.3.4 Apr, 2011]