Result of FASTA (omim) for
pF1KB5977
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5977, 519 aa
1>>>pF1KB5977 519 - 519 aa - 519 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.5485+/-0.000377; mu= 3.0379+/- 0.024
mean_var=162.6372+/-33.345, 0's: 0 Z-trim(118.0): 39 B-trim: 390 in 1/55
Lambda= 0.100569
statistics sampled from 30476 (30518) to 30476 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.358), width: 16
Scan time: 8.820
The best scores are: opt bits E(85289)
NP_003091 (OMIM: 605929) sorting nexin-2 isoform 1 ( 519) 3334 495.9 1.2e-139
NP_001265128 (OMIM: 605929) sorting nexin-2 isofor ( 402) 2576 385.9 1.2e-106
NP_003090 (OMIM: 601272) sorting nexin-1 isoform a ( 522) 1894 287.0 9.5e-77
NP_001229862 (OMIM: 601272) sorting nexin-1 isofor ( 557) 1799 273.2 1.4e-72
NP_683758 (OMIM: 601272) sorting nexin-1 isoform b ( 457) 1766 268.4 3.3e-71
XP_005254668 (OMIM: 601272) PREDICTED: sorting nex ( 399) 1647 251.1 4.6e-66
XP_006710741 (OMIM: 614904) PREDICTED: sorting nex ( 387) 307 56.6 1.5e-07
XP_016856914 (OMIM: 614904) PREDICTED: sorting nex ( 387) 307 56.6 1.5e-07
XP_011539866 (OMIM: 614904) PREDICTED: sorting nex ( 387) 307 56.6 1.5e-07
XP_016856915 (OMIM: 614904) PREDICTED: sorting nex ( 387) 307 56.6 1.5e-07
XP_016856916 (OMIM: 614904) PREDICTED: sorting nex ( 387) 307 56.6 1.5e-07
NP_057060 (OMIM: 614904) sorting nexin-7 isoform a ( 451) 307 56.7 1.7e-07
XP_016856917 (OMIM: 614904) PREDICTED: sorting nex ( 336) 299 55.5 3e-07
XP_006710740 (OMIM: 614904) PREDICTED: sorting nex ( 422) 299 55.5 3.7e-07
NP_003786 (OMIM: 605930) sorting nexin-3 isoform a ( 162) 231 45.4 0.00015
NP_037478 (OMIM: 300883) sorting nexin-12 isoform ( 162) 217 43.4 0.00061
NP_001243114 (OMIM: 300883) sorting nexin-12 isofo ( 162) 217 43.4 0.00061
NP_689419 (OMIM: 606098) sorting nexin-6 isoform b ( 418) 219 43.9 0.0011
NP_003785 (OMIM: 605931) sorting nexin-4 [Homo sap ( 450) 218 43.8 0.0013
XP_016862903 (OMIM: 605931) PREDICTED: sorting nex ( 482) 206 42.0 0.0047
NP_001243117 (OMIM: 300883) sorting nexin-12 isofo ( 158) 194 40.1 0.0061
NP_055241 (OMIM: 605937) sorting nexin-5 isoform a ( 404) 201 41.3 0.0067
NP_689413 (OMIM: 605937) sorting nexin-5 isoform a ( 404) 201 41.3 0.0067
>>NP_003091 (OMIM: 605929) sorting nexin-2 isoform 1 [Ho (519 aa)
initn: 3334 init1: 3334 opt: 3334 Z-score: 2628.0 bits: 495.9 E(85289): 1.2e-139
Smith-Waterman score: 3334; 100.0% identity (100.0% similar) in 519 aa overlap (1-519:1-519)
10 20 30 40 50 60
pF1KB5 MAAEREPPPLGDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAEDISANSNGPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAAEREPPPLGDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAEDISANSNGPK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PTEVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PTEVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 RYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 ESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTAL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 QITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEK
430 440 450 460 470 480
490 500 510
pF1KB5 ERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA
:::::::::::::::::::::::::::::::::::::::
NP_003 ERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA
490 500 510
>>NP_001265128 (OMIM: 605929) sorting nexin-2 isoform 2 (402 aa)
initn: 2576 init1: 2576 opt: 2576 Z-score: 2035.4 bits: 385.9 E(85289): 1.2e-106
Smith-Waterman score: 2576; 100.0% identity (100.0% similar) in 402 aa overlap (118-519:1-402)
90 100 110 120 130 140
pF1KB5 REPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVS
::::::::::::::::::::::::::::::
NP_001 MSAPVIFDRSREEIEEEANGDIFDIEIGVS
10 20 30
150 160 170 180 190 200
pF1KB5 DPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPP
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB5 APEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSEL
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB5 PRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSV
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB5 EALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFY
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB5 MFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAK
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB5 NEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKY
340 350 360 370 380 390
510
pF1KB5 WEAFLPEAKAIA
::::::::::::
NP_001 WEAFLPEAKAIA
400
>>NP_003090 (OMIM: 601272) sorting nexin-1 isoform a [Ho (522 aa)
initn: 2007 init1: 1868 opt: 1894 Z-score: 1498.8 bits: 287.0 E(85289): 9.5e-77
Smith-Waterman score: 1971; 60.1% identity (79.6% similar) in 534 aa overlap (2-519:10-522)
10 20 30 40
pF1KB5 MAAEREPPPL-----------GDGKPTDFEDLEDGEDLFTSTVSTLESSPSS
:.:: :::. : ..: .. .:::.::. ... :. .:
NP_003 MASGGGGCSASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTG--AAVVSKHQS
10 20 30 40 50
50 60 70 80 90
pF1KB5 PEPAS--LPAEDISANSNGPKPTEVVLDDDRE--DLFAEATEEVSLDSPEREPILSSEPS
:. .. :: .:: : . . ..:.: ::::.:: :.:::: . .
NP_003 PKITTSLLPI------NNGSKENGIHEEQDQEPQDLFADATVELSLDSTQNNQ-------
60 70 80 90 100
100 110 120 130 140 150
pF1KB5 PAVTPVTPTTLIA-PRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGM
: :::. : :. . : : . . ::.::: . : ::. .:..::::.::::
NP_003 ---KKVLAKTLISLPPQEATNSSKP---QPTYEELEEEEQEDQFDLTVGITDPEKIGDGM
110 120 130 140 150
160 170 180 190 200 210
pF1KB5 NAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGM
:::.::.:::.::: .: ...:.:::::::::::. ::. :. . :.:::: ::::..::
NP_003 NAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGM
160 170 180 190 200 210
220 230 240 250 260 270
pF1KB5 TKVKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQAL
::::::::::::.::.::::::::::::: :.:::.:::::.:.:::. ::::::.::.:
NP_003 TKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTL
220 230 240 250 260 270
280 290 300 310 320 330
pF1KB5 SGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKE
::::.:.: :::.:::.:::::::::: ::::: :. : .:.:::::. ::.:: ::::
NP_003 SGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKE
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB5 LSANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDY
:. ::: :::: ::::.:::.:::::::::::::::::.::::::: ::....::::::
NP_003 LALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDY
340 350 360 370 380 390
400 410 420 430 440 450
pF1KB5 IRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAK
:::.: :...::.::: ::.:.::: :: :::::::... ::::::.::::.:: :::..
NP_003 IRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESR
400 410 420 430 440 450
460 470 480 490 500 510
pF1KB5 VQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAK
: : :::::.:: ..:::: :::::. ::::. .:::::.:. .:::: :::::::::::
NP_003 VTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAK
460 470 480 490 500 510
pF1KB5 AIA
::.
NP_003 AIS
520
>>NP_001229862 (OMIM: 601272) sorting nexin-1 isoform d (557 aa)
initn: 1888 init1: 1774 opt: 1799 Z-score: 1423.9 bits: 273.2 E(85289): 1.4e-72
Smith-Waterman score: 1876; 59.3% identity (79.7% similar) in 516 aa overlap (2-503:10-506)
10 20 30 40
pF1KB5 MAAEREPPPL-----------GDGKPTDFEDLEDGEDLFTSTVSTLESSPSS
:.:: :::. : ..: .. .:::.::. ... :. .:
NP_001 MASGGGGCSASERLPPPFPGLEPESEGAAGGSEPEAGDSDTEGEDIFTG--AAVVSKHQS
10 20 30 40 50
50 60 70 80 90
pF1KB5 PEPAS--LPAEDISANSNGPKPTEVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPA
:. .. :: .. : . :: . . :.. .::::.:: :.:::: . .
NP_001 PKITTSLLPINNGSKE-NGIHEEQ---DQEPQDLFADATVELSLDSTQNNQ---------
60 70 80 90 100
100 110 120 130 140 150
pF1KB5 VTPVTPTTLIA-PRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNA
: :::. : :. . : : . . ::.::: . : ::. .:..::::.::::::
NP_001 -KKVLAKTLISLPPQEATNSSKP---QPTYEELEEEEQEDQFDLTVGITDPEKIGDGMNA
110 120 130 140 150 160
160 170 180 190 200 210
pF1KB5 YMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTK
:.::.:::.::: .: ...:.:::::::::::. ::. :. . :.:::: ::::..::::
NP_001 YVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTK
170 180 190 200 210 220
220 230 240 250 260 270
pF1KB5 VKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSG
::::::::::.::.::::::::::::: :.:::.:::::.:.:::. ::::::.::.:::
NP_001 VKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSG
230 240 250 260 270 280
280 290 300 310 320 330
pF1KB5 AGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELS
::.:.: :::.:::.:::::::::: ::::: :. : .:.:::::. ::.:: :::::.
NP_001 AGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELA
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB5 ANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIR
::: :::: ::::.:::.:::::::::::::::::.::::::: ::....::::::::
NP_001 LNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIR
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB5 LIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQ
:.: :...::.::: ::.:.::: :: :::::::... ::::::.::::.:: :::..:
NP_001 LLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESRVT
410 420 430 440 450 460
460 470 480 490 500 510
pF1KB5 QGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAI
: :::::.:: ..:::: :::::. ::::. .:::::.:. .:::
NP_001 QYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQAGEQLGIRSGILLTK
470 480 490 500 510 520
pF1KB5 A
NP_001 KLPRYSKFFSTVHKFCAAASLWKWGFFLSAYLSYLF
530 540 550
>>NP_683758 (OMIM: 601272) sorting nexin-1 isoform b [Ho (457 aa)
initn: 1844 init1: 1766 opt: 1766 Z-score: 1399.4 bits: 268.4 E(85289): 3.3e-71
Smith-Waterman score: 1773; 60.2% identity (79.5% similar) in 487 aa overlap (33-519:9-457)
10 20 30 40 50 60
pF1KB5 AEREPPPLGDGKPTDFEDLEDGEDLFTSTVSTLESSPSSPEPASLPAEDISANSNGPKPT
:. : : : :. : . .:... :.
NP_683 MASGGGGCSASERLPP-PFPGLEPESEGAAGGSEPEAG
10 20 30
70 80 90 100 110 120
pF1KB5 EVVLDDDREDLFAEATEEVSLDSPEREPILSSEPSPAVTPVTPTTLIAPRIESKSMSAPV
. : . ::.:. :. ..:.. :: .: :.:. : :.. : .
NP_683 DS--DTEGEDIFTGAA------------VVSKHQSPKIT----TSLL-P-INNGSKENGI
40 50 60 70
130 140 150 160 170 180
pF1KB5 IFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKR
.:: ..: . :.: .:::::::.::.:::.::: .: ...:.:::
NP_683 -----HEEQDQEPQ-DLF-----------AGDGMNAYVAYKVTTQTSLPLFRSKQFAVKR
80 90 100 110 120
190 200 210 220 230 240
pF1KB5 RFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERY
::::::::. ::. :. . :.:::: ::::..::::::::::::::.::.::::::::::
NP_683 RFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERY
130 140 150 160 170 180
250 260 270 280 290 300
pF1KB5 LQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNES
::: :.:::.:::::.:.:::. ::::::.::.:::::.:.: :::.:::.:::::::::
NP_683 LQRIVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNES
190 200 210 220 230 240
310 320 330 340 350 360
pF1KB5 DAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSR
: ::::: :. : .:.:::::. ::.:: :::::. ::: :::: ::::.:::.:::::
NP_683 DIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSR
250 260 270 280 290 300
370 380 390 400 410 420
pF1KB5 ALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQI
::::::::::::.::::::: ::....:::::::::.: :...::.::: ::.:.:::
NP_683 ALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQA
310 320 330 340 350 360
430 440 450 460 470 480
pF1KB5 TLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKER
:: :::::::... ::::::.::::.:: :::..: : :::::.:: ..:::: :::::.
NP_683 TLQKKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEK
370 380 390 400 410 420
490 500 510
pF1KB5 VKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA
::::. .:::::.:. .:::: :::::::::::::.
NP_683 SKDFKNHVIKYLETLLYSQQQLAKYWEAFLPEAKAIS
430 440 450
>>XP_005254668 (OMIM: 601272) PREDICTED: sorting nexin-1 (399 aa)
initn: 1647 init1: 1647 opt: 1647 Z-score: 1307.0 bits: 251.1 E(85289): 4.6e-66
Smith-Waterman score: 1647; 71.6% identity (89.9% similar) in 348 aa overlap (156-503:1-348)
130 140 150 160 170 180
pF1KB5 RSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFS
::::.::.:::.::: .: ...:.::::::
XP_005 MNAYVAYKVTTQTSLPLFRSKQFAVKRRFS
10 20 30
190 200 210 220 230 240
pF1KB5 DFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERYLQR
:::::. ::. :. . :.:::: ::::..::::::::::::::.::.:::::::::::::
XP_005 DFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERYLQR
40 50 60 70 80 90
250 260 270 280 290 300
pF1KB5 TVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAW
:.:::.:::::.:.:::. ::::::.::.:::::.:.: :::.:::.:::::::::: :
XP_005 IVNHPTMLQDPDVREFLEKEELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIW
100 110 120 130 140 150
310 320 330 340 350 360
pF1KB5 FEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAAMLGNSEDHTALSRALS
:::: :. : .:.:::::. ::.:: :::::. ::: :::: ::::.:::.::::::::
XP_005 FEEKLQEVECEEQRLRKLHAVVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALS
160 170 180 190 200 210
370 380 390 400 410 420
pF1KB5 QLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLL
:::::::::.::::::: ::....:::::::::.: :...::.::: ::.:.::: ::
XP_005 QLAEVEEKIEQLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQ
220 230 240 250 260 270
430 440 450 460 470 480
pF1KB5 KKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKD
:::::::... ::::::.::::.:: :::..: : :::::.:: ..:::: :::::. ::
XP_005 KKREAEARLLWANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKD
280 290 300 310 320 330
490 500 510
pF1KB5 FKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA
::. .:::::.:. .:::
XP_005 FKNHVIKYLETLLYSQQQAGEQLGIRSGILLTKKLPRYSKFFSTVHKFCAAASLWKWGFF
340 350 360 370 380 390
>>XP_006710741 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa)
initn: 327 init1: 163 opt: 307 Z-score: 256.4 bits: 56.6 E(85289): 1.5e-07
Smith-Waterman score: 355; 24.4% identity (58.2% similar) in 340 aa overlap (130-465:20-346)
100 110 120 130 140 150
pF1KB5 VTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAY
.:. : . :. :. : :..::. ....
XP_006 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETF
10 20 30 40
160 170 180 190 200 210
pF1KB5 MAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKV
..::. :::: . :..::: :.::..::: :..:: : :.:: ::: ::
XP_006 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVK----
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB5 KVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGA
: . . .:.: :: ::...:.: . :::: . :.. :: .. .... .:
XP_006 --GMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE--LSSHKKQGP
110 120 130 140 150
280 290 300 310 320 330
pF1KB5 GILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSA
:.: ..... :: . ... : : .. .: ..:.. . . . ...:
XP_006 GLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFD
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 NTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRL
. .. . . ::. : .:...: .. . ... . . .. .:.
XP_006 EMKEYGPIHILWSASEED--LVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLY
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 IAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMM---VANKPDKIQQAKNEIR-EWEA
. ::. .: . : :... .: ..:.. .. ... ::.. :.: .. .::
XP_006 SEMLMGVMKRRDQI-QAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWER
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB5 KVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEA
:. . :..
XP_006 WKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP
340 350 360 370 380
>>XP_016856914 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa)
initn: 327 init1: 163 opt: 307 Z-score: 256.4 bits: 56.6 E(85289): 1.5e-07
Smith-Waterman score: 355; 24.4% identity (58.2% similar) in 340 aa overlap (130-465:20-346)
100 110 120 130 140 150
pF1KB5 VTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAY
.:. : . :. :. : :..::. ....
XP_016 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETF
10 20 30 40
160 170 180 190 200 210
pF1KB5 MAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKV
..::. :::: . :..::: :.::..::: :..:: : :.:: ::: ::
XP_016 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVK----
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB5 KVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGA
: . . .:.: :: ::...:.: . :::: . :.. :: .. .... .:
XP_016 --GMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE--LSSHKKQGP
110 120 130 140 150
280 290 300 310 320 330
pF1KB5 GILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSA
:.: ..... :: . ... : : .. .: ..:.. . . . ...:
XP_016 GLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFD
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 NTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRL
. .. . . ::. : .:...: .. . ... . . .. .:.
XP_016 EMKEYGPIHILWSASEED--LVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLY
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 IAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMM---VANKPDKIQQAKNEIR-EWEA
. ::. .: . : :... .: ..:.. .. ... ::.. :.: .. .::
XP_016 SEMLMGVMKRRDQI-QAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWER
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB5 KVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEA
:. . :..
XP_016 WKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP
340 350 360 370 380
>>XP_011539866 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa)
initn: 327 init1: 163 opt: 307 Z-score: 256.4 bits: 56.6 E(85289): 1.5e-07
Smith-Waterman score: 355; 24.4% identity (58.2% similar) in 340 aa overlap (130-465:20-346)
100 110 120 130 140 150
pF1KB5 VTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAY
.:. : . :. :. : :..::. ....
XP_011 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETF
10 20 30 40
160 170 180 190 200 210
pF1KB5 MAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKV
..::. :::: . :..::: :.::..::: :..:: : :.:: ::: ::
XP_011 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVK----
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB5 KVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGA
: . . .:.: :: ::...:.: . :::: . :.. :: .. .... .:
XP_011 --GMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE--LSSHKKQGP
110 120 130 140 150
280 290 300 310 320 330
pF1KB5 GILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSA
:.: ..... :: . ... : : .. .: ..:.. . . . ...:
XP_011 GLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFD
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 NTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRL
. .. . . ::. : .:...: .. . ... . . .. .:.
XP_011 EMKEYGPIHILWSASEED--LVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLY
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 IAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMM---VANKPDKIQQAKNEIR-EWEA
. ::. .: . : :... .: ..:.. .. ... ::.. :.: .. .::
XP_011 SEMLMGVMKRRDQI-QAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWER
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB5 KVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEA
:. . :..
XP_011 WKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP
340 350 360 370 380
>>XP_016856915 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa)
initn: 327 init1: 163 opt: 307 Z-score: 256.4 bits: 56.6 E(85289): 1.5e-07
Smith-Waterman score: 355; 24.4% identity (58.2% similar) in 340 aa overlap (130-465:20-346)
100 110 120 130 140 150
pF1KB5 VTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAY
.:. : . :. :. : :..::. ....
XP_016 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETF
10 20 30 40
160 170 180 190 200 210
pF1KB5 MAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKV
..::. :::: . :..::: :.::..::: :..:: : :.:: ::: ::
XP_016 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVK----
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB5 KVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGA
: . . .:.: :: ::...:.: . :::: . :.. :: .. .... .:
XP_016 --GMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE--LSSHKKQGP
110 120 130 140 150
280 290 300 310 320 330
pF1KB5 GILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSA
:.: ..... :: . ... : : .. .: ..:.. . . . ...:
XP_016 GLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFD
160 170 180 190 200 210
340 350 360 370 380 390
pF1KB5 NTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRL
. .. . . ::. : .:...: .. . ... . . .. .:.
XP_016 EMKEYGPIHILWSASEED--LVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLY
220 230 240 250 260 270
400 410 420 430 440 450
pF1KB5 IAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMM---VANKPDKIQQAKNEIR-EWEA
. ::. .: . : :... .: ..:.. .. ... ::.. :.: .. .::
XP_016 SEMLMGVMKRRDQI-QAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWER
280 290 300 310 320 330
460 470 480 490 500 510
pF1KB5 KVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEA
:. . :..
XP_016 WKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP
340 350 360 370 380
519 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 21:41:57 2016 done: Fri Nov 4 21:41:59 2016
Total Scan time: 8.820 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]