Result of FASTA (omim) for
pF1KB5974
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5974, 560 aa
1>>>pF1KB5974 560 - 560 aa - 560 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.9971+/-0.000446; mu= -2.7602+/- 0.027
mean_var=288.8497+/-61.102, 0's: 0 Z-trim(118.2): 98 B-trim: 1174 in 1/59
Lambda= 0.075464
statistics sampled from 30889 (30995) to 30889 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.363), width: 16
Scan time: 10.180
The best scores are: opt bits E(85289)
NP_001128660 (OMIM: 600862) arf-GAP domain and FG ( 560) 3682 414.8 3.6e-115
NP_004495 (OMIM: 600862) arf-GAP domain and FG rep ( 562) 3668 413.3 1e-114
XP_006712543 (OMIM: 600862) PREDICTED: arf-GAP dom ( 578) 3094 350.8 6.8e-96
XP_016859443 (OMIM: 600862) PREDICTED: arf-GAP dom ( 345) 2113 243.8 6.5e-64
XP_005246573 (OMIM: 600862) PREDICTED: arf-GAP dom ( 586) 1971 228.6 4.4e-59
XP_006712542 (OMIM: 600862) PREDICTED: arf-GAP dom ( 600) 1954 226.7 1.6e-58
XP_006712541 (OMIM: 600862) PREDICTED: arf-GAP dom ( 602) 1953 226.6 1.7e-58
NP_001128659 (OMIM: 600862) arf-GAP domain and FG ( 584) 1922 223.2 1.8e-57
NP_001128661 (OMIM: 600862) arf-GAP domain and FG ( 522) 1778 207.5 8.5e-53
XP_006712544 (OMIM: 600862) PREDICTED: arf-GAP dom ( 385) 1324 158.0 5.1e-38
XP_005250363 (OMIM: 604019) PREDICTED: arf-GAP dom ( 492) 917 113.8 1.3e-24
NP_006067 (OMIM: 604019) arf-GAP domain and FG rep ( 481) 908 112.8 2.6e-24
XP_016867602 (OMIM: 604019) PREDICTED: arf-GAP dom ( 295) 871 108.6 2.9e-23
XP_016867601 (OMIM: 604019) PREDICTED: arf-GAP dom ( 394) 641 83.6 1.3e-15
XP_005248817 (OMIM: 611372) PREDICTED: stromal mem ( 250) 245 40.4 0.0085
>>NP_001128660 (OMIM: 600862) arf-GAP domain and FG repe (560 aa)
initn: 3682 init1: 3682 opt: 3682 Z-score: 2188.7 bits: 414.8 E(85289): 3.6e-115
Smith-Waterman score: 3682; 100.0% identity (100.0% similar) in 560 aa overlap (1-560:1-560)
10 20 30 40 50 60
pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPF
490 500 510 520 530 540
550 560
pF1KB5 MTGAPTGQFPTGSSSTNPFL
::::::::::::::::::::
NP_001 MTGAPTGQFPTGSSSTNPFL
550 560
>>NP_004495 (OMIM: 600862) arf-GAP domain and FG repeat- (562 aa)
initn: 3368 init1: 3368 opt: 3668 Z-score: 2180.5 bits: 413.3 E(85289): 1e-114
Smith-Waterman score: 3668; 99.6% identity (99.6% similar) in 562 aa overlap (1-560:1-562)
10 20 30 40 50 60
pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNG--FAAFGQTKPVVTPFGQVAAAGVSSN
::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
NP_004 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSN
490 500 510 520 530 540
540 550 560
pF1KB5 PFMTGAPTGQFPTGSSSTNPFL
::::::::::::::::::::::
NP_004 PFMTGAPTGQFPTGSSSTNPFL
550 560
>>XP_006712543 (OMIM: 600862) PREDICTED: arf-GAP domain (578 aa)
initn: 3318 init1: 3010 opt: 3094 Z-score: 1842.6 bits: 350.8 E(85289): 6.8e-96
Smith-Waterman score: 3626; 96.9% identity (96.9% similar) in 578 aa overlap (1-560:1-578)
10 20 30 40 50 60
pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS
370 380 390 400 410 420
430 440 450 460
pF1KB5 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGAT----------------AATFG
::::::::::::::::::::::::::::::::::::::: :::::
XP_006 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATGLSGAMHSQVFPHAHFAATFG
430 440 450 460 470 480
470 480 490 500 510 520
pF1KB5 TASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNG--FAAFGQTKP
::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::
XP_006 TASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKP
490 500 510 520 530 540
530 540 550 560
pF1KB5 VVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
::::::::::::::::::::::::::::::::::::::
XP_006 VVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
550 560 570
>>XP_016859443 (OMIM: 600862) PREDICTED: arf-GAP domain (345 aa)
initn: 1813 init1: 1813 opt: 2113 Z-score: 1268.4 bits: 243.8 E(85289): 6.5e-64
Smith-Waterman score: 2113; 99.4% identity (99.4% similar) in 331 aa overlap (232-560:15-345)
210 220 230 240 250 260
pF1KB5 DLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTA
::::::::::::::::::::::::::::::
XP_016 MDTSTTKSCLAYLIAQNSANADFANFDAFGQSSGSSNFGGFPTA
10 20 30 40
270 280 290 300 310 320
pF1KB5 SHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGL
50 60 70 80 90 100
330 340 350 360 370 380
pF1KB5 QTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELD
110 120 130 140 150 160
390 400 410 420 430 440
pF1KB5 SVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAG
170 180 190 200 210 220
450 460 470 480 490 500
pF1KB5 PSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAF
230 240 250 260 270 280
510 520 530 540 550
pF1KB5 PQQTAFSQQPNG--FAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPF
:::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPF
290 300 310 320 330 340
560
pF1KB5 L
:
XP_016 L
>>XP_005246573 (OMIM: 600862) PREDICTED: arf-GAP domain (586 aa)
initn: 2241 init1: 1839 opt: 1971 Z-score: 1181.7 bits: 228.6 E(85289): 4.4e-59
Smith-Waterman score: 3602; 95.4% identity (95.6% similar) in 586 aa overlap (1-560:1-586)
10 20 30 40 50 60
pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
190 200 210 220 230 240
250 260 270
pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTG------------------------GSAA
:::::::::::::::::::::::::::::::. ::::
XP_005 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB5 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNG--F
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_005 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGF
490 500 510 520 530 540
520 530 540 550 560
pF1KB5 AAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
550 560 570 580
>>XP_006712542 (OMIM: 600862) PREDICTED: arf-GAP domain (600 aa)
initn: 2574 init1: 1839 opt: 1954 Z-score: 1171.6 bits: 226.7 E(85289): 1.6e-58
Smith-Waterman score: 3524; 93.1% identity (93.2% similar) in 592 aa overlap (1-552:1-592)
10 20 30 40 50 60
pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
190 200 210 220 230 240
250 260 270
pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTG------------------------GSAA
:::::::::::::::::::::::::::::::. ::::
XP_006 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR
430 440 450 460 470 480
460 470 480 490 500
pF1KB5 GAT----------------AATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAA
::: :::::::::::::::::::::::::::::::::::::::::
XP_006 GATGLSGAMHSQVFPHAHFAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAA
490 500 510 520 530 540
510 520 530 540 550 560
pF1KB5 FPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FPQQTAFSQQPNGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
550 560 570 580 590 600
>>XP_006712541 (OMIM: 600862) PREDICTED: arf-GAP domain (602 aa)
initn: 2260 init1: 1839 opt: 1953 Z-score: 1171.0 bits: 226.6 E(85289): 1.7e-58
Smith-Waterman score: 3497; 92.7% identity (92.9% similar) in 592 aa overlap (1-550:1-592)
10 20 30 40 50 60
pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
190 200 210 220 230 240
250 260 270
pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTG------------------------GSAA
:::::::::::::::::::::::::::::::. ::::
XP_006 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR
430 440 450 460 470 480
460 470 480 490 500
pF1KB5 GAT----------------AATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAA
::: :::::::::::::::::::::::::::::::::::::::::
XP_006 GATGLSGAMHSQVFPHAHFAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAA
490 500 510 520 530 540
510 520 530 540 550
pF1KB5 FPQQTAFSQQPNG--FAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNP
::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_006 FPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNP
550 560 570 580 590 600
560
pF1KB5 FL
XP_006 FL
>>NP_001128659 (OMIM: 600862) arf-GAP domain and FG repe (584 aa)
initn: 1980 init1: 1850 opt: 1922 Z-score: 1152.9 bits: 223.2 E(85289): 1.8e-57
Smith-Waterman score: 3616; 95.7% identity (95.9% similar) in 584 aa overlap (1-560:1-584)
10 20 30 40 50 60
pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
190 200 210 220 230 240
250 260 270
pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTG------------------------GSAA
:::::::::::::::::::::::::::::::. ::::
NP_001 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAA
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVNANFAHFDNFPKSSSADFGTFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNI
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSAGQGGDQGSGFGTTGKAPVGSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTS
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSNASSNVFGTVPVVASAQTQPASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNAR
430 440 450 460 470 480
460 470 480 490 500 510
pF1KB5 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GATAATFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGFAA
490 500 510 520 530 540
520 530 540 550 560
pF1KB5 FGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGQTKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
550 560 570 580
>>NP_001128661 (OMIM: 600862) arf-GAP domain and FG repe (522 aa)
initn: 2012 init1: 1563 opt: 1778 Z-score: 1068.9 bits: 207.5 E(85289): 8.5e-53
Smith-Waterman score: 3306; 92.5% identity (92.5% similar) in 562 aa overlap (1-560:1-522)
10 20 30 40 50 60
pF1KB5 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAASAKRKQEEKHLKMLRDMTGLPHNRKCFDCDQRGPTYVNMTVGSFVCTSCSGSLRGLN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPHRVKSISMTTFTQQEIEFLQKHGNEVCKQIWLGLFDDRSSAIPDFRDPQKVKEFLQEK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEKKRWYVPPEQAKVVASVHASISGSSASSTSSTPEVKPLKSLLGDSAPTLHLNKGTPSQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADF
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPVVGRSQGQQQEKKQFDLLSDLGSDIFAAPAPQSTATANFANFAHFNSHA---------
190 200 210 220 230
250 260 270 280 290 300
pF1KB5 ANFDAFGQSSGSSNFGGFPTASHSPFQPQTTGGSAASVNANFAHFDNFPKSSSADFGTFN
:::::::::::::::::::::::::::::
NP_001 -------------------------------GGSAASVNANFAHFDNFPKSSSADFGTFN
240 250 260
310 320 330 340 350 360
pF1KB5 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPVGSV
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB5 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQPAS
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB5 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATAATFGTASMSMPTGFGTPAPY
390 400 410 420 430 440
490 500 510 520 530
pF1KB5 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNG--FAAFGQTKPVVTPFGQVAAAGVSSN
::::::::::::::::::::::::::::::::: :::::::::::::::::::::::::
NP_001 SLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQTKPVVTPFGQVAAAGVSSN
450 460 470 480 490 500
540 550 560
pF1KB5 PFMTGAPTGQFPTGSSSTNPFL
::::::::::::::::::::::
NP_001 PFMTGAPTGQFPTGSSSTNPFL
510 520
>>XP_006712544 (OMIM: 600862) PREDICTED: arf-GAP domain (385 aa)
initn: 1486 init1: 1178 opt: 1324 Z-score: 803.5 bits: 158.0 E(85289): 5.1e-38
Smith-Waterman score: 2005; 88.4% identity (88.7% similar) in 371 aa overlap (232-560:15-385)
210 220 230 240 250 260
pF1KB5 DLGSDIFAAPAPQSTATANFANFAHFNSHAAQNSANADFANFDAFGQSSGSSNFGGFPTA
::::::::::::::::::::::::::::::
XP_006 MDTSTTKSCLAYLIAQNSANADFANFDAFGQSSGSSNFGGFPTA
10 20 30 40
270 280 290
pF1KB5 SHSPFQPQTTG------------------------GSAASVNANFAHFDNFPKSSSADFG
::::::::::. :::::::::::::::::::::::::
XP_006 SHSPFQPQTTAFRMLSSSCSFGEFTSAFPLQATHSGSAASVNANFAHFDNFPKSSSADFG
50 60 70 80 90 100
300 310 320 330 340 350
pF1KB5 TFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFNTSQSHQTASAVSKVSTNKAGLQTADKYAALANLDNIFSAGQGGDQGSGFGTTGKAPV
110 120 130 140 150 160
360 370 380 390 400 410
pF1KB5 GSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSVVSVPSQSSASSDKYAALAELDSVFSSAATSSNAYTSTSNASSNVFGTVPVVASAQTQ
170 180 190 200 210 220
420 430 440 450 460
pF1KB5 PASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGAT----------------AA
:::::::::::::::::::::::::::::::::::::::::: ::
XP_006 PASSSVPAPFGATPSTNPFVAAAGPSVASSTNPFQTNARGATGLSGAMHSQVFPHAHFAA
230 240 250 260 270 280
470 480 490 500 510
pF1KB5 TFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNG--FAAFGQ
:::::::::::::::::::::::::::::::::::::::::::::::::::: ::::::
XP_006 TFGTASMSMPTGFGTPAPYSLPTSFSGSFQQPAFPAQAAFPQQTAFSQQPNGAGFAAFGQ
290 300 310 320 330 340
520 530 540 550 560
pF1KB5 TKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
:::::::::::::::::::::::::::::::::::::::::
XP_006 TKPVVTPFGQVAAAGVSSNPFMTGAPTGQFPTGSSSTNPFL
350 360 370 380
560 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 10:49:55 2016 done: Sat Nov 5 10:49:56 2016
Total Scan time: 10.180 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]