Result of FASTA (omim) for
pF1KB5941
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5941, 508 aa
1>>>pF1KB5941 508 - 508 aa - 508 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1609+/-0.000287; mu= 15.4886+/- 0.018
mean_var=112.9622+/-22.878, 0's: 0 Z-trim(121.1): 91 B-trim: 0 in 0/54
Lambda= 0.120672
statistics sampled from 37077 (37178) to 37077 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.436), width: 16
Scan time: 11.350
The best scores are: opt bits E(85289)
NP_000112 (OMIM: 133100,133171) erythropoietin rec ( 508) 3509 621.5 1.8e-177
NP_005364 (OMIM: 159530,254450,601977,604498) thro ( 635) 262 56.3 3.1e-07
XP_016856809 (OMIM: 159530,254450,601977,604498) P ( 692) 262 56.4 3.3e-07
NP_001191245 (OMIM: 176761,615554,615555) prolacti ( 376) 241 52.5 2.6e-06
NP_001191244 (OMIM: 176761,615554,615555) prolacti ( 349) 236 51.6 4.5e-06
XP_011512370 (OMIM: 176761,615554,615555) PREDICTE ( 622) 236 51.8 6.9e-06
XP_006714547 (OMIM: 176761,615554,615555) PREDICTE ( 622) 236 51.8 6.9e-06
XP_011512371 (OMIM: 176761,615554,615555) PREDICTE ( 622) 236 51.8 6.9e-06
NP_000940 (OMIM: 176761,615554,615555) prolactin r ( 622) 236 51.8 6.9e-06
NP_001191246 (OMIM: 176761,615554,615555) prolacti ( 288) 223 49.2 1.9e-05
XP_016865135 (OMIM: 176761,615554,615555) PREDICTE ( 309) 223 49.3 2e-05
NP_851564 (OMIM: 147050,605383,615207) interleukin ( 538) 223 49.5 3e-05
XP_016878746 (OMIM: 147050,605383,615207) PREDICTE ( 538) 223 49.5 3e-05
NP_068570 (OMIM: 147050,605383,615207) interleukin ( 538) 223 49.5 3e-05
XP_011544159 (OMIM: 147050,605383,615207) PREDICTE ( 560) 223 49.5 3.1e-05
NP_851565 (OMIM: 147050,605383,615207) interleukin ( 560) 223 49.5 3.1e-05
XP_011526726 (OMIM: 272430,604237) PREDICTED: cyto ( 404) 213 47.6 8.1e-05
XP_011526725 (OMIM: 272430,604237) PREDICTED: cyto ( 419) 213 47.6 8.3e-05
NP_004741 (OMIM: 272430,604237) cytokine receptor- ( 422) 213 47.6 8.3e-05
XP_011526724 (OMIM: 272430,604237) PREDICTED: cyto ( 423) 213 47.6 8.3e-05
NP_000386 (OMIM: 138981,614370) cytokine receptor ( 897) 214 48.1 0.00013
XP_005261397 (OMIM: 138981,614370) PREDICTED: cyto ( 903) 210 47.4 0.00021
XP_011528206 (OMIM: 138981,614370) PREDICTED: cyto ( 909) 210 47.4 0.00021
XP_011528205 (OMIM: 138981,614370) PREDICTED: cyto ( 915) 206 46.7 0.00034
NP_000197 (OMIM: 300400,308380,312863) cytokine re ( 369) 198 45.0 0.00046
NP_001191247 (OMIM: 176761,615554,615555) prolacti ( 268) 194 44.2 0.00059
XP_016885541 (OMIM: 300007) PREDICTED: interleukin ( 381) 194 44.3 0.00076
XP_016884992 (OMIM: 300007) PREDICTED: interleukin ( 381) 194 44.3 0.00076
XP_016884991 (OMIM: 300007) PREDICTED: interleukin ( 386) 194 44.3 0.00077
XP_016885540 (OMIM: 300007) PREDICTED: interleukin ( 386) 194 44.3 0.00077
XP_011529458 (OMIM: 300007) PREDICTED: interleukin ( 449) 194 44.4 0.00086
XP_011543953 (OMIM: 300007) PREDICTED: interleukin ( 449) 194 44.4 0.00086
XP_011529457 (OMIM: 300007) PREDICTED: interleukin ( 460) 194 44.4 0.00088
XP_011543952 (OMIM: 300007) PREDICTED: interleukin ( 460) 194 44.4 0.00088
XP_016885538 (OMIM: 300007) PREDICTED: interleukin ( 499) 194 44.4 0.00093
XP_016884989 (OMIM: 300007) PREDICTED: interleukin ( 499) 194 44.4 0.00093
XP_011529456 (OMIM: 300007) PREDICTED: interleukin ( 500) 194 44.4 0.00094
XP_016884988 (OMIM: 300007) PREDICTED: interleukin ( 500) 194 44.4 0.00094
XP_016885537 (OMIM: 300007) PREDICTED: interleukin ( 500) 194 44.4 0.00094
XP_016884986 (OMIM: 300007) PREDICTED: interleukin ( 500) 194 44.4 0.00094
XP_016885536 (OMIM: 300007) PREDICTED: interleukin ( 500) 194 44.4 0.00094
XP_016884987 (OMIM: 300007) PREDICTED: interleukin ( 500) 194 44.4 0.00094
XP_016885535 (OMIM: 300007) PREDICTED: interleukin ( 500) 194 44.4 0.00094
XP_011543951 (OMIM: 300007) PREDICTED: interleukin ( 500) 194 44.4 0.00094
NP_002177 (OMIM: 300007) interleukin-9 receptor is ( 521) 194 44.4 0.00096
XP_011543948 (OMIM: 300007) PREDICTED: interleukin ( 560) 194 44.4 0.001
XP_011529454 (OMIM: 300007) PREDICTED: interleukin ( 560) 194 44.4 0.001
XP_016885533 (OMIM: 300007) PREDICTED: interleukin ( 567) 194 44.4 0.001
XP_016884984 (OMIM: 300007) PREDICTED: interleukin ( 567) 194 44.4 0.001
XP_011529453 (OMIM: 300007) PREDICTED: interleukin ( 568) 194 44.4 0.001
>>NP_000112 (OMIM: 133100,133171) erythropoietin recepto (508 aa)
initn: 3509 init1: 3509 opt: 3509 Z-score: 3307.3 bits: 621.5 E(85289): 1.8e-177
Smith-Waterman score: 3509; 100.0% identity (100.0% similar) in 508 aa overlap (1-508:1-508)
10 20 30 40 50 60
pF1KB5 MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 VCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 ELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ELRVTAASGAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EVDVSAGNGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 SLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SLLTPSDLDPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KGNFQLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SEHAQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGAS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 AASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 AASFEYTILDPSSQLLRPWTLCPELPPTPPHLKYLYLVVSDSGISTDYSSGDSQGAQGGL
430 440 450 460 470 480
490 500
pF1KB5 SDGPYSNPYENSLIPAAEPLPPSYVACS
::::::::::::::::::::::::::::
NP_000 SDGPYSNPYENSLIPAAEPLPPSYVACS
490 500
>>NP_005364 (OMIM: 159530,254450,601977,604498) thrombop (635 aa)
initn: 269 init1: 143 opt: 262 Z-score: 251.0 bits: 56.3 E(85289): 3.1e-07
Smith-Waterman score: 265; 25.1% identity (51.1% similar) in 395 aa overlap (5-382:249-605)
10 20 30
pF1KB5 MDHLGASLWPQVGSL--CLLLAGA--AWAPPPNL
: : : :. : . :.:. .:. : ..
NP_005 QDGPKQTSPSREASALTAEGGSCLISGLQPGNSYWLQLRSEPDGISLGGSWGSWSLPVTV
220 230 240 250 260 270
40 50 60 70 80
pF1KB5 PDPKFESKAALLAARGPEELLCFTERLEDLVCFWEE---AASAGVGPGNYSFSYQLEDEP
: . :. :. : ::: :....: :.. :.: : . . . :
NP_005 DLP---GDAVALG------LQCFTLDLKNVTCQWQQQDHASSQGFFYHSRARCCPRDRYP
280 290 300 310 320
90 100 110 120 130 140
pF1KB5 -WKLCRLHQA--PTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYH--RVIHINEV
:. :. .. : . : . . . .:.. . ..::.: :. . . . :...
NP_005 IWENCEEEEKTNPGLQTPQFSRCHFKSRN-DSIIHILVEVTTAPGTVHSYLGSPFWIHQA
330 340 350 360 370 380
150 160 170 180 190 200
pF1KB5 VLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGR
: : .: .: : . :::. :.: : . ... :.. . :.: . . .: :
NP_005 VRLPTP-NLHWREIS-SGHLELEW-QHPSSWAAQETCYQLRYT-GEGHQDWKVLEPPLGA
390 400 410 420 430 440
210 220 230 240 250
pF1KB5 TECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSDLD--PLILTLSLIL-
.: .:: :.:: . .:::. :.. : ::.::.:. . : .. :. .: :.:
NP_005 RGGTL-ELRPRSRYRLQLRARLNGPTYQGPWSSWSDPTRVETATETAWISLVTALHLVLG
450 460 470 480 490 500
260 270 280 290 300 310
pF1KB5 --VVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWW
.:. .:: . .: : :.. .::..:. :. : : :
NP_005 LSAVLGLLLLRWQFPAHYRRLRHALWPSLPD----------LHR---VLGQYLRDT----
510 520 530 540
320 330 340 350 360 370
pF1KB5 SPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLDKWLLP
. .: : :.. :. .. . : .... :: :. : .:: : :. :
NP_005 AALSP----PKATVSDTCEEVEPSLLEILPKSSERTPL--PLCSSQAQMDYRRLQPSCLG
550 560 570 580 590 600
380 390 400 410 420 430
pF1KB5 RNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGASAASFEYTILDPSSQLLR
: :
NP_005 TMPLSVCPPMAESGSCCTTHIANHSYLPLSYWQQP
610 620 630
>--
initn: 156 init1: 113 opt: 227 Z-score: 218.1 bits: 50.2 E(85289): 2.1e-05
Smith-Waterman score: 227; 28.2% identity (53.3% similar) in 195 aa overlap (16-205:12-194)
10 20 30 40 50 60
pF1KB5 MDHLGASLWPQVGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDL
::::: : :: . :. . : : : : ::.. .:::
NP_005 MPSWALFMVTSCLLLA------PQNL--AQVSSQDVSLLASDSEPLKCFSRTFEDL
10 20 30 40
70 80 90 100 110
pF1KB5 VCFWEEAASAGVGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSS-FVP
.:::.: .: :.:.. : : . : : . . ..:. :..: . : :
NP_005 TCFWDEEEAAP--SGTYQLLYAYPREKPRACPLSSQSMPHFGTRYVCQFPDQEEVRLFFP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 LELRVTAAS-GAPRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPP-PETPMTSH
:.: : . . : .::. .. : : : . : ... :.. . : : :: ...
NP_005 LHLWVKNVFLNQTRTQRVLFVDSVGLPAPPSIIKAMGGSQPGELQISWEEPAPE--ISDF
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB5 IRYEVDVSAGNGAGSV--QRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSA
.:::. . . .:. .... .: :
NP_005 LRYELRYGPRDPKNSTGPTVIQLIATETCCPALQRPHSASALDQSPCAQPTMPWQDGPKQ
170 180 190 200 210 220
>>XP_016856809 (OMIM: 159530,254450,601977,604498) PREDI (692 aa)
initn: 242 init1: 143 opt: 262 Z-score: 250.5 bits: 56.4 E(85289): 3.3e-07
Smith-Waterman score: 265; 25.1% identity (51.1% similar) in 395 aa overlap (5-382:306-662)
10 20 30
pF1KB5 MDHLGASLWPQVGSL--CLLLAGA--AWAPPPNL
: : : :. : . :.:. .:. : ..
XP_016 QDGPKQTSPSREASALTAEGGSCLISGLQPGNSYWLQLRSEPDGISLGGSWGSWSLPVTV
280 290 300 310 320 330
40 50 60 70 80
pF1KB5 PDPKFESKAALLAARGPEELLCFTERLEDLVCFWEE---AASAGVGPGNYSFSYQLEDEP
: . :. :. : ::: :....: :.. :.: : . . . :
XP_016 DLP---GDAVALG------LQCFTLDLKNVTCQWQQQDHASSQGFFYHSRARCCPRDRYP
340 350 360 370 380
90 100 110 120 130 140
pF1KB5 -WKLCRLHQA--PTARGAVRFWCSLPTADTSSFVPLELRVTAASGAPRYH--RVIHINEV
:. :. .. : . : . . . .:.. . ..::.: :. . . . :...
XP_016 IWENCEEEEKTNPGLQTPQFSRCHFKSRN-DSIIHILVEVTTAPGTVHSYLGSPFWIHQA
390 400 410 420 430 440
150 160 170 180 190 200
pF1KB5 VLLDAPVGLVARLADESGHVVLRWLPPPETPMTSHIRYEVDVSAGNGAGSVQRVEILEGR
: : .: .: : . :::. :.: : . ... :.. . :.: . . .: :
XP_016 VRLPTP-NLHWREIS-SGHLELEW-QHPSSWAAQETCYQLRYT-GEGHQDWKVLEPPLGA
450 460 470 480 490 500
210 220 230 240 250
pF1KB5 TECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSDLD--PLILTLSLIL-
.: .:: :.:: . .:::. :.. : ::.::.:. . : .. :. .: :.:
XP_016 RGGTL-ELRPRSRYRLQLRARLNGPTYQGPWSSWSDPTRVETATETAWISLVTALHLVLG
510 520 530 540 550 560
260 270 280 290 300 310
pF1KB5 --VVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNFQLWLYQNDGCLWW
.:. .:: . .: : :.. .::..:. :. : : :
XP_016 LSAVLGLLLLRWQFPAHYRRLRHALWPSLPD----------LHR---VLGQYLRDT----
570 580 590 600
320 330 340 350 360 370
pF1KB5 SPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHAQDTYLVLDKWLLP
. .: : :.. :. .. . : .... :: :. : .:: : :. :
XP_016 AALSP----PKATVSDTCEEVEPSLLEILPKSSERTPL--PLCSSQAQMDYRRLQPSCLG
610 620 630 640 650
380 390 400 410 420 430
pF1KB5 RNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGASAASFEYTILDPSSQLLR
: :
XP_016 TMPLSVCPPMAESGSCCTTHIANHSYLPLSYWQQP
660 670 680 690
>--
initn: 156 init1: 113 opt: 208 Z-score: 199.7 bits: 47.0 E(85289): 0.00022
Smith-Waterman score: 208; 27.2% identity (54.4% similar) in 169 aa overlap (42-205:87-251)
20 30 40 50 60 70
pF1KB5 VGSLCLLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAG
: : : : ::.. .:::.:::.: .:
XP_016 RGSPAGPLPFHINMPGRTQGQLTSCSLDVSLLASDSEPLKCFSRTFEDLTCFWDEEEAAP
60 70 80 90 100 110
80 90 100 110 120
pF1KB5 VGPGNYSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSS-FVPLELRVTAAS-G
:.:.. : : . : : . . ..:. :..: . : ::.: : . .
XP_016 --SGTYQLLYAYPREKPRACPLSSQSMPHFGTRYVCQFPDQEEVRLFFPLHLWVKNVFLN
120 130 140 150 160 170
130 140 150 160 170 180
pF1KB5 APRYHRVIHINEVVLLDAPVGLVARLADESGHVVLRWLPP-PETPMTSHIRYEVDVSAGN
: .::. .. : : : . : ... :.. . : : :: ... .:::. . .
XP_016 QTRTQRVLFVDSVGLPAPPSIIKAMGGSQPGELQISWEEPAPE--ISDFLRYELRYGPRD
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB5 GAGSV--QRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPS
.:. .... .: :
XP_016 PKNSTGPTVIQLIATETCCPALQRPHSASALDQSPCAQPTMPWQDGPKQTSPSREASALT
240 250 260 270 280 290
>>NP_001191245 (OMIM: 176761,615554,615555) prolactin re (376 aa)
initn: 91 init1: 63 opt: 241 Z-score: 234.3 bits: 52.5 E(85289): 2.6e-06
Smith-Waterman score: 241; 21.9% identity (51.4% similar) in 333 aa overlap (47-366:31-349)
20 30 40 50 60 70
pF1KB5 LLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGN
:: . : . : ..:.:. ....:. : :
NP_001 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGL-PTN
10 20 30 40 50
80 90 100 110 120 130
pF1KB5 YSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAAS--GAPRYH
::..:. : : .:. : . : . :: . . :.:.. :.
NP_001 YSLTYHREGETL----MHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSD
60 70 80 90 100 110
140 150 160 170 180
pF1KB5 RV-IHINEVVLLDAPVGLVARLA---DESGHVVLRWLPPPETPMTSH---IRYEVDVSAG
.. . .. .: : :. :.... :.. .. ..: :: . . . ::. ..
NP_001 ELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 NGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD
..: .... .:: . .:. .: :: . :. : .::::: . . :::
NP_001 KAAE--WEIHFAGQQTEFKILSLHPGQKYLVQVRCK---PDHG-YWSAWSPATFIQIPSD
180 190 200 210 220
250 260 270 280 290 300
pF1KB5 L---DPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNF
. : . .: ... :. : :. . .. :.: .:.:. . .::.
NP_001 FTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 QLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEG-PLLEPVGSEH
. : . :: . : . . . ::: . . :.. ..: ::. .:. :
NP_001 EE-LLSALGCQDFPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGDPLM--LGASH
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 AQDTYLVLDKWLLPRNPPSEDLPGPGGSVDIVAMDEGSEASSCSSALASKPSPEGASAAS
..
NP_001 YKNLKSYRPRKISSQGRLAVFTKATLTTVQ
350 360 370
>>NP_001191244 (OMIM: 176761,615554,615555) prolactin re (349 aa)
initn: 63 init1: 63 opt: 236 Z-score: 230.0 bits: 51.6 E(85289): 4.5e-06
Smith-Waterman score: 236; 22.4% identity (51.5% similar) in 299 aa overlap (47-333:31-317)
20 30 40 50 60 70
pF1KB5 LLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGN
:: . : . : ..:.:. ....:. : :
NP_001 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGL-PTN
10 20 30 40 50
80 90 100 110 120 130
pF1KB5 YSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAAS--GAPRYH
::..:. : : .:. : . : . :: . . :.:.. :.
NP_001 YSLTYHREGETL----MHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSD
60 70 80 90 100 110
140 150 160 170 180
pF1KB5 RV-IHINEVVLLDAPVGLVARLA---DESGHVVLRWLPPPETPMTSH---IRYEVDVSAG
.. . .. .: : :. :.... :.. .. ..: :: . . . ::. ..
NP_001 ELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 NGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD
..: .... .:: . .:. .: :: . :. : .::::: . . :::
NP_001 KAAE--WEIHFAGQQTEFKILSLHPGQKYLVQVRCK---PDHG-YWSAWSPATFIQIPSD
180 190 200 210 220
250 260 270 280 290 300
pF1KB5 L---DPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNF
. : . .: ... :. : :. . .. :.: .:.:. . .::.
NP_001 FTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 QLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHA
. : . :: . : . . . :::
NP_001 EE-LLSALGCQDFPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQEREQRQAQEARD
290 300 310 320 330 340
>>XP_011512370 (OMIM: 176761,615554,615555) PREDICTED: p (622 aa)
initn: 63 init1: 63 opt: 236 Z-score: 226.7 bits: 51.8 E(85289): 6.9e-06
Smith-Waterman score: 236; 22.4% identity (51.5% similar) in 299 aa overlap (47-333:31-317)
20 30 40 50 60 70
pF1KB5 LLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGN
:: . : . : ..:.:. ....:. : :
XP_011 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGL-PTN
10 20 30 40 50
80 90 100 110 120 130
pF1KB5 YSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAAS--GAPRYH
::..:. : : .:. : . : . :: . . :.:.. :.
XP_011 YSLTYHREGETL----MHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSD
60 70 80 90 100 110
140 150 160 170 180
pF1KB5 RV-IHINEVVLLDAPVGLVARLA---DESGHVVLRWLPPPETPMTSH---IRYEVDVSAG
.. . .. .: : :. :.... :.. .. ..: :: . . . ::. ..
XP_011 ELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 NGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD
..: .... .:: . .:. .: :: . :. : .::::: . . :::
XP_011 KAAE--WEIHFAGQQTEFKILSLHPGQKYLVQVRCK---PDHG-YWSAWSPATFIQIPSD
180 190 200 210 220
250 260 270 280 290 300
pF1KB5 L---DPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNF
. : . .: ... :. : :. . .. :.: .:.:. . .::.
XP_011 FTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 QLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHA
. : . :: . : . . . :::
XP_011 EE-LLSALGCQDFPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTD
290 300 310 320 330 340
>>XP_006714547 (OMIM: 176761,615554,615555) PREDICTED: p (622 aa)
initn: 63 init1: 63 opt: 236 Z-score: 226.7 bits: 51.8 E(85289): 6.9e-06
Smith-Waterman score: 236; 22.4% identity (51.5% similar) in 299 aa overlap (47-333:31-317)
20 30 40 50 60 70
pF1KB5 LLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGN
:: . : . : ..:.:. ....:. : :
XP_006 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGL-PTN
10 20 30 40 50
80 90 100 110 120 130
pF1KB5 YSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAAS--GAPRYH
::..:. : : .:. : . : . :: . . :.:.. :.
XP_006 YSLTYHREGETL----MHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSD
60 70 80 90 100 110
140 150 160 170 180
pF1KB5 RV-IHINEVVLLDAPVGLVARLA---DESGHVVLRWLPPPETPMTSH---IRYEVDVSAG
.. . .. .: : :. :.... :.. .. ..: :: . . . ::. ..
XP_006 ELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 NGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD
..: .... .:: . .:. .: :: . :. : .::::: . . :::
XP_006 KAAE--WEIHFAGQQTEFKILSLHPGQKYLVQVRCK---PDHG-YWSAWSPATFIQIPSD
180 190 200 210 220
250 260 270 280 290 300
pF1KB5 L---DPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNF
. : . .: ... :. : :. . .. :.: .:.:. . .::.
XP_006 FTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 QLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHA
. : . :: . : . . . :::
XP_006 EE-LLSALGCQDFPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTD
290 300 310 320 330 340
>>XP_011512371 (OMIM: 176761,615554,615555) PREDICTED: p (622 aa)
initn: 63 init1: 63 opt: 236 Z-score: 226.7 bits: 51.8 E(85289): 6.9e-06
Smith-Waterman score: 236; 22.4% identity (51.5% similar) in 299 aa overlap (47-333:31-317)
20 30 40 50 60 70
pF1KB5 LLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGN
:: . : . : ..:.:. ....:. : :
XP_011 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGL-PTN
10 20 30 40 50
80 90 100 110 120 130
pF1KB5 YSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAAS--GAPRYH
::..:. : : .:. : . : . :: . . :.:.. :.
XP_011 YSLTYHREGETL----MHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSD
60 70 80 90 100 110
140 150 160 170 180
pF1KB5 RV-IHINEVVLLDAPVGLVARLA---DESGHVVLRWLPPPETPMTSH---IRYEVDVSAG
.. . .. .: : :. :.... :.. .. ..: :: . . . ::. ..
XP_011 ELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 NGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD
..: .... .:: . .:. .: :: . :. : .::::: . . :::
XP_011 KAAE--WEIHFAGQQTEFKILSLHPGQKYLVQVRCK---PDHG-YWSAWSPATFIQIPSD
180 190 200 210 220
250 260 270 280 290 300
pF1KB5 L---DPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNF
. : . .: ... :. : :. . .. :.: .:.:. . .::.
XP_011 FTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 QLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHA
. : . :: . : . . . :::
XP_011 EE-LLSALGCQDFPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTD
290 300 310 320 330 340
>>NP_000940 (OMIM: 176761,615554,615555) prolactin recep (622 aa)
initn: 63 init1: 63 opt: 236 Z-score: 226.7 bits: 51.8 E(85289): 6.9e-06
Smith-Waterman score: 236; 22.4% identity (51.5% similar) in 299 aa overlap (47-333:31-317)
20 30 40 50 60 70
pF1KB5 LLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGN
:: . : . : ..:.:. ....:. : :
NP_000 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGL-PTN
10 20 30 40 50
80 90 100 110 120 130
pF1KB5 YSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAAS--GAPRYH
::..:. : : .:. : . : . :: . . :.:.. :.
NP_000 YSLTYHREGETL----MHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSD
60 70 80 90 100 110
140 150 160 170 180
pF1KB5 RV-IHINEVVLLDAPVGLVARLA---DESGHVVLRWLPPPETPMTSH---IRYEVDVSAG
.. . .. .: : :. :.... :.. .. ..: :: . . . ::. ..
NP_000 ELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 NGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD
..: .... .:: . .:. .: :: . :. : .::::: . . :::
NP_000 KAAE--WEIHFAGQQTEFKILSLHPGQKYLVQVRCK---PDHG-YWSAWSPATFIQIPSD
180 190 200 210 220
250 260 270 280 290 300
pF1KB5 L---DPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNF
. : . .: ... :. : :. . .. :.: .:.:. . .::.
NP_000 FTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEKGKS
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 QLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHA
. : . :: . : . . . :::
NP_000 EE-LLSALGCQDFPPTSDYEDLLVEYLEVDDSEDQHLMSVHSKEHPSQGMKPTYLDPDTD
290 300 310 320 330 340
>>NP_001191246 (OMIM: 176761,615554,615555) prolactin re (288 aa)
initn: 63 init1: 63 opt: 223 Z-score: 218.9 bits: 49.2 E(85289): 1.9e-05
Smith-Waterman score: 223; 22.7% identity (53.1% similar) in 256 aa overlap (47-290:31-275)
20 30 40 50 60 70
pF1KB5 LLLAGAAWAPPPNLPDPKFESKAALLAARGPEELLCFTERLEDLVCFWEEAASAGVGPGN
:: . : . : ..:.:. ....:. : :
NP_001 MKENVASATVFTLLLFLNTCLLNGQLPPGKPEIFKCRSPNKETFTCWWRPGTDGGL-PTN
10 20 30 40 50
80 90 100 110 120 130
pF1KB5 YSFSYQLEDEPWKLCRLHQAPTARGAVRFWCSLPTADTSSFVPLELRVTAAS--GAPRYH
::..:. : : .:. : . : . :: . . :.:.. :.
NP_001 YSLTYHREGETL----MHECPDYITGGPNSCHFGKQYTSMWRTYIMMVNATNQMGSSFSD
60 70 80 90 100 110
140 150 160 170 180
pF1KB5 RV-IHINEVVLLDAPVGLVARLA---DESGHVVLRWLPPPETPMTSH---IRYEVDVSAG
.. . .. .: : :. :.... :.. .. ..: :: . . . ::. ..
NP_001 ELYVDVTYIVQPDPPLELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 NGAGSVQRVEILEGRTECVLSNLRGRTRYTFAVRARMAEPSFGGFWSAWSEPVSLLTPSD
..: .... .:: . .:. .: :: . :. : .::::: . . :::
NP_001 KAA--EWEIHFAGQQTEFKILSLHPGQKYLVQVRCK---PDHG-YWSAWSPATFIQIPSD
180 190 200 210 220
250 260 270 280 290 300
pF1KB5 L---DPLILTLSLILVVILVLLTVLALLSHRRALKQKIWPGIPSPESEFEGLFTTHKGNF
. : . .: ... :. : :. . .. :.: .:.:.
NP_001 FTMNDTTVWISVAVLSAVICLIIVWAVALKGYSMVTCIFPPVPGPKIKGFDAHLLEVTP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 QLWLYQNDGCLWWSPCTPFTEDPPASLEVLSERCWGTMQAVEPGTDDEGPLLEPVGSEHA
508 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 15:38:53 2016 done: Sat Nov 5 15:38:55 2016
Total Scan time: 11.350 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]