Result of FASTA (omim) for
pF1KB5864
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5864, 491 aa
1>>>pF1KB5864 491 - 491 aa - 491 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6398+/-0.000421; mu= 11.2376+/- 0.026
mean_var=112.1409+/-23.495, 0's: 0 Z-trim(114.3): 419 B-trim: 420 in 2/51
Lambda= 0.121113
statistics sampled from 23517 (24039) to 23517 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.653), E-opt: 0.2 (0.282), width: 16
Scan time: 8.230
The best scores are: opt bits E(85289)
NP_783860 (OMIM: 613528) synaptotagmin-9 [Homo sap ( 491) 3359 598.3 1.6e-170
XP_011518206 (OMIM: 613528) PREDICTED: synaptotagm ( 492) 3346 596.0 7.8e-170
XP_011518203 (OMIM: 613528) PREDICTED: synaptotagm ( 564) 3346 596.1 8.7e-170
XP_011518202 (OMIM: 613528) PREDICTED: synaptotagm ( 567) 3346 596.1 8.7e-170
XP_011518204 (OMIM: 613528) PREDICTED: synaptotagm ( 535) 3001 535.8 1.2e-151
XP_011518209 (OMIM: 613528) PREDICTED: synaptotagm ( 349) 2396 429.9 5.5e-120
XP_011518208 (OMIM: 613528) PREDICTED: synaptotagm ( 351) 2396 429.9 5.5e-120
NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo ( 425) 1776 321.7 2.6e-87
NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sap ( 425) 1776 321.7 2.6e-87
XP_016855860 (OMIM: 607718) PREDICTED: synaptotagm ( 443) 1776 321.7 2.7e-87
NP_001153800 (OMIM: 600327) synaptotagmin-3 [Homo ( 590) 1296 237.9 6e-62
XP_011525693 (OMIM: 600327) PREDICTED: synaptotagm ( 590) 1296 237.9 6e-62
XP_011525692 (OMIM: 600327) PREDICTED: synaptotagm ( 590) 1296 237.9 6e-62
NP_001153801 (OMIM: 600327) synaptotagmin-3 [Homo ( 590) 1296 237.9 6e-62
NP_115674 (OMIM: 600327) synaptotagmin-3 [Homo sap ( 590) 1296 237.9 6e-62
XP_006723403 (OMIM: 600782) PREDICTED: synaptotagm ( 385) 949 177.1 7.7e-44
XP_005269170 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 947 176.8 1e-43
NP_001278830 (OMIM: 185605) synaptotagmin-1 isofor ( 419) 947 176.8 1e-43
XP_006719639 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 947 176.8 1e-43
XP_011537012 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 947 176.8 1.1e-43
XP_016875398 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 947 176.8 1.1e-43
NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 ( 422) 947 176.8 1.1e-43
NP_001129277 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 947 176.8 1.1e-43
NP_001129278 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 947 176.8 1.1e-43
XP_016882664 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 940 175.6 2.3e-43
XP_016882665 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 940 175.6 2.3e-43
XP_006723402 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 940 175.6 2.3e-43
NP_003171 (OMIM: 600782) synaptotagmin-5 isoform 1 ( 386) 940 175.6 2.3e-43
NP_796376 (OMIM: 600104,616040) synaptotagmin-2 [H ( 419) 934 174.5 5e-43
NP_001129976 (OMIM: 600104,616040) synaptotagmin-2 ( 419) 934 174.5 5e-43
XP_016855802 (OMIM: 600104,616040) PREDICTED: syna ( 419) 934 174.5 5e-43
XP_016855801 (OMIM: 600104,616040) PREDICTED: syna ( 422) 934 174.5 5.1e-43
XP_016855800 (OMIM: 600104,616040) PREDICTED: syna ( 422) 934 174.5 5.1e-43
XP_011507494 (OMIM: 600104,616040) PREDICTED: syna ( 422) 934 174.5 5.1e-43
XP_016855799 (OMIM: 600104,616040) PREDICTED: syna ( 476) 934 174.6 5.6e-43
XP_016855798 (OMIM: 600104,616040) PREDICTED: syna ( 479) 934 174.6 5.6e-43
NP_001284703 (OMIM: 600782) synaptotagmin-5 isofor ( 382) 922 172.4 2e-42
XP_006723404 (OMIM: 600782) PREDICTED: synaptotagm ( 383) 913 170.8 6e-42
XP_011543643 (OMIM: 604146) PREDICTED: synaptotagm ( 453) 842 158.5 3.7e-38
XP_006718799 (OMIM: 604146) PREDICTED: synaptotagm ( 293) 838 157.7 4.2e-38
NP_004191 (OMIM: 604146) synaptotagmin-7 isoform 2 ( 403) 838 157.8 5.5e-38
XP_011543645 (OMIM: 604146) PREDICTED: synaptotagm ( 409) 838 157.8 5.5e-38
NP_001287702 (OMIM: 604146) synaptotagmin-7 isofor ( 447) 838 157.8 6e-38
XP_005274444 (OMIM: 604146) PREDICTED: synaptotagm ( 449) 838 157.8 6e-38
NP_001238994 (OMIM: 604146) synaptotagmin-7 isofor ( 478) 838 157.8 6.3e-38
XP_011543642 (OMIM: 604146) PREDICTED: synaptotagm ( 484) 838 157.8 6.3e-38
XP_011543641 (OMIM: 604146) PREDICTED: synaptotagm ( 528) 838 157.8 6.8e-38
XP_005274442 (OMIM: 604146) PREDICTED: synaptotagm ( 611) 838 157.9 7.7e-38
XP_011543640 (OMIM: 604146) PREDICTED: synaptotagm ( 617) 838 157.9 7.7e-38
XP_005274441 (OMIM: 604146) PREDICTED: synaptotagm ( 642) 838 157.9 8e-38
>>NP_783860 (OMIM: 613528) synaptotagmin-9 [Homo sapiens (491 aa)
initn: 3359 init1: 3359 opt: 3359 Z-score: 3182.4 bits: 598.3 E(85289): 1.6e-170
Smith-Waterman score: 3359; 100.0% identity (100.0% similar) in 491 aa overlap (1-491:1-491)
10 20 30 40 50 60
pF1KB5 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_783 EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKP
430 440 450 460 470 480
490
pF1KB5 IAHWHSLVEKR
:::::::::::
NP_783 IAHWHSLVEKR
490
>>XP_011518206 (OMIM: 613528) PREDICTED: synaptotagmin-9 (492 aa)
initn: 3346 init1: 3346 opt: 3346 Z-score: 3170.1 bits: 596.0 E(85289): 7.8e-170
Smith-Waterman score: 3346; 100.0% identity (100.0% similar) in 489 aa overlap (1-489:1-489)
10 20 30 40 50 60
pF1KB5 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKP
430 440 450 460 470 480
490
pF1KB5 IAHWHSLVEKR
:::::::::
XP_011 IAHWHSLVEAHG
490
>>XP_011518203 (OMIM: 613528) PREDICTED: synaptotagmin-9 (564 aa)
initn: 3346 init1: 3346 opt: 3346 Z-score: 3169.2 bits: 596.1 E(85289): 8.7e-170
Smith-Waterman score: 3346; 100.0% identity (100.0% similar) in 489 aa overlap (1-489:1-489)
10 20 30 40 50 60
pF1KB5 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKP
430 440 450 460 470 480
490
pF1KB5 IAHWHSLVEKR
:::::::::
XP_011 IAHWHSLVEIKEPHFPLRTHPSSPSNHVVWVEASTSSAPGMSLHLPRLKPNHHIQGLVRE
490 500 510 520 530 540
>>XP_011518202 (OMIM: 613528) PREDICTED: synaptotagmin-9 (567 aa)
initn: 3346 init1: 3346 opt: 3346 Z-score: 3169.2 bits: 596.1 E(85289): 8.7e-170
Smith-Waterman score: 3346; 100.0% identity (100.0% similar) in 489 aa overlap (1-489:1-489)
10 20 30 40 50 60
pF1KB5 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKP
430 440 450 460 470 480
490
pF1KB5 IAHWHSLVEKR
:::::::::
XP_011 IAHWHSLVEIKEPHFPLRTHPSSPSNHVVWVEASTSSAPGMSLHLPRLKPNHHIQGLVRG
490 500 510 520 530 540
>>XP_011518204 (OMIM: 613528) PREDICTED: synaptotagmin-9 (535 aa)
initn: 3001 init1: 3001 opt: 3001 Z-score: 2843.8 bits: 535.8 E(85289): 1.2e-151
Smith-Waterman score: 3001; 100.0% identity (100.0% similar) in 441 aa overlap (49-489:17-457)
20 30 40 50 60 70
pF1KB5 LCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVTACGLALFGVSLFVSWKLC
::::::::::::::::::::::::::::::
XP_011 MLAKVVEGDLAFKGGRDISVSLLTLVVTACGLALFGVSLFVSWKLC
10 20 30 40
80 90 100 110 120 130
pF1KB5 WVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPTPCPDSSMKISHTSPDIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPTPCPDSSMKISHTSPDIPL
50 60 70 80 90 100
140 150 160 170 180 190
pF1KB5 STQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 STQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGRI
110 120 130 140 150 160
200 210 220 230 240 250
pF1KB5 KPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDP
170 180 190 200 210 220
260 270 280 290 300 310
pF1KB5 YVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDL
230 240 250 260 270 280
320 330 340 350 360 370
pF1KB5 IGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARN
290 300 310 320 330 340
380 390 400 410 420 430
pF1KB5 LKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLS
350 360 370 380 390 400
440 450 460 470 480 490
pF1KB5 IAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVEKR
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVEIKEPHFPLR
410 420 430 440 450 460
XP_011 THPSSPSNHVVWVEASTSSAPGMSLHLPRLKPNHHIQGLVRGECVTQFRPRNFVGTIRKS
470 480 490 500 510 520
>>XP_011518209 (OMIM: 613528) PREDICTED: synaptotagmin-9 (349 aa)
initn: 2396 init1: 2396 opt: 2396 Z-score: 2275.1 bits: 429.9 E(85289): 5.5e-120
Smith-Waterman score: 2396; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348)
10 20 30 40 50 60
pF1KB5 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNG
310 320 330 340
370 380 390 400 410 420
pF1KB5 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN
>>XP_011518208 (OMIM: 613528) PREDICTED: synaptotagmin-9 (351 aa)
initn: 2396 init1: 2396 opt: 2396 Z-score: 2275.1 bits: 429.9 E(85289): 5.5e-120
Smith-Waterman score: 2396; 100.0% identity (100.0% similar) in 348 aa overlap (1-348:1-348)
10 20 30 40 50 60
pF1KB5 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGARDALCHQALQLLAELCARGALEHDSCQDFIYHLRDRARPRLRDPDISVSLLTLVVT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHNSIRRQLNLSNPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVDLGELMFSL
::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIEYVTNILS
310 320 330 340 350
370 380 390 400 410 420
pF1KB5 CYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYN
>>NP_001257734 (OMIM: 607718) synaptotagmin-6 [Homo sapi (425 aa)
initn: 1583 init1: 1583 opt: 1776 Z-score: 1688.4 bits: 321.7 E(85289): 2.6e-87
Smith-Waterman score: 1776; 62.2% identity (84.1% similar) in 415 aa overlap (80-489:1-413)
50 60 70 80 90 100
pF1KB5 ISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQ
.:::.. : :. : ::. ... . .
NP_001 MPWRNKEASSPSSAN--PPLEALQSPSFRG
10 20
110 120 130 140 150 160
pF1KB5 ENSEDFLDPPT-PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHN
. .. . :: : ....:::::::::: .: ...:. . .:.:::.:::.::.::.
NP_001 NMADKLKDPSTLGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTRLQRQTTEPASSTRHT
30 40 50 60 70 80
170 180 190 200 210 220
pF1KB5 SIRR----QLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKL
:..: :...:. :.. . :: :.:::::::::::.:.:..:.. .:.:::.
NP_001 SFKRHLPRQMHVSSVDYGNELPPAAEQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGKI
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB5 NFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPV
:: :.:: . : :::.: :: .:::::: :.:::::::::::::: : ::.::::::::.
NP_001 NFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPT
150 160 170 180 190 200
290 300 310 320 330 340
pF1KB5 FDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIE
::: : :::::..: ::::.::.:::::::::.::.:..:.... .:. :: .::::.
NP_001 FDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQ
210 220 230 240 250 260
350 360 370 380 390 400
pF1KB5 YVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLK
:.:...:::::.::::::::::::::.:.:: :::::::::: :::::::::.:::::::
NP_001 YATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLK
270 280 290 300 310 320
410 420 430 440 450 460
pF1KB5 KRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAER
:.::. :.:::::::::::.::.::::.::. : :.::::::::::::::::.:: ::
NP_001 KKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEG
330 340 350 360 370 380
470 480 490
pF1KB5 LGRDHWSEMLSYPRKPIAHWHSLVEKR
::::::.:::.::::::::::::::
NP_001 LGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKEGNPRL
390 400 410 420
>>NP_995320 (OMIM: 607718) synaptotagmin-6 [Homo sapiens (425 aa)
initn: 1583 init1: 1583 opt: 1776 Z-score: 1688.4 bits: 321.7 E(85289): 2.6e-87
Smith-Waterman score: 1776; 62.2% identity (84.1% similar) in 415 aa overlap (80-489:1-413)
50 60 70 80 90 100
pF1KB5 ISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQ
.:::.. : :. : ::. ... . .
NP_995 MPWRNKEASSPSSAN--PPLEALQSPSFRG
10 20
110 120 130 140 150 160
pF1KB5 ENSEDFLDPPT-PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHN
. .. . :: : ....:::::::::: .: ...:. . .:.:::.:::.::.::.
NP_995 NMADKLKDPSTLGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTRLQRQTTEPASSTRHT
30 40 50 60 70 80
170 180 190 200 210 220
pF1KB5 SIRR----QLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKL
:..: :...:. :.. . :: :.:::::::::::.:.:..:.. .:.:::.
NP_995 SFKRHLPRQMHVSSVDYGNELPPAAEQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGKI
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB5 NFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPV
:: :.:: . : :::.: :: .:::::: :.:::::::::::::: : ::.::::::::.
NP_995 NFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPT
150 160 170 180 190 200
290 300 310 320 330 340
pF1KB5 FDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIE
::: : :::::..: ::::.::.:::::::::.::.:..:.... .:. :: .::::.
NP_995 FDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQ
210 220 230 240 250 260
350 360 370 380 390 400
pF1KB5 YVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLK
:.:...:::::.::::::::::::::.:.:: :::::::::: :::::::::.:::::::
NP_995 YATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLK
270 280 290 300 310 320
410 420 430 440 450 460
pF1KB5 KRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAER
:.::. :.:::::::::::.::.::::.::. : :.::::::::::::::::.:: ::
NP_995 KKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEG
330 340 350 360 370 380
470 480 490
pF1KB5 LGRDHWSEMLSYPRKPIAHWHSLVEKR
::::::.:::.::::::::::::::
NP_995 LGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKEGNPRL
390 400 410 420
>>XP_016855860 (OMIM: 607718) PREDICTED: synaptotagmin-6 (443 aa)
initn: 1583 init1: 1583 opt: 1776 Z-score: 1688.2 bits: 321.7 E(85289): 2.7e-87
Smith-Waterman score: 1776; 62.2% identity (84.1% similar) in 415 aa overlap (80-489:1-413)
50 60 70 80 90 100
pF1KB5 ISVSLLTLVVTACGLALFGVSLFVSWKLCWVPWRERGLPSGSKDNNQEPLNYMDTETNEQ
.:::.. : :. : ::. ... . .
XP_016 MPWRNKEASSPSSAN--PPLEALQSPSFRG
10 20
110 120 130 140 150 160
pF1KB5 ENSEDFLDPPT-PCPDSSMKISHTSPDIPLSTQTGIQENCAHGVRVQRQVTEPTSSARHN
. .. . :: : ....:::::::::: .: ...:. . .:.:::.:::.::.::.
XP_016 NMADKLKDPSTLGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTRLQRQTTEPASSTRHT
30 40 50 60 70 80
170 180 190 200 210 220
pF1KB5 SIRR----QLNLSNPDFNIQQLQKQEQLTGIGRIKPELYKQRSLDNDDGRRSNSKACGKL
:..: :...:. :.. . :: :.:::::::::::.:.:..:.. .:.:::.
XP_016 SFKRHLPRQMHVSSVDYGNELPPAAEQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGKI
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB5 NFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLPDRKTKHQTKVHRKTLNPV
:: :.:: . : :::.: :: .:::::: :.:::::::::::::: : ::.::::::::.
XP_016 NFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPT
150 160 170 180 190 200
290 300 310 320 330 340
pF1KB5 FDEVFLFPVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVVDHFLDLADFPRECILWKDIE
::: : :::::..: ::::.::.:::::::::.::.:..:.... .:. :: .::::.
XP_016 FDENFHFPVPYEELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQ
210 220 230 240 250 260
350 360 370 380 390 400
pF1KB5 YVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLK
:.:...:::::.::::::::::::::.:.:: :::::::::: :::::::::.:::::::
XP_016 YATSESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLK
270 280 290 300 310 320
410 420 430 440 450 460
pF1KB5 KRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAER
:.::. :.:::::::::::.::.::::.::. : :.::::::::::::::::.:: ::
XP_016 KKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEG
330 340 350 360 370 380
470 480 490
pF1KB5 LGRDHWSEMLSYPRKPIAHWHSLVEKR
::::::.:::.::::::::::::::
XP_016 LGRDHWNEMLAYPRKPIAHWHSLVEVKKSFKEWQGRAASFDSESSCPSPKPPPTP
390 400 410 420 430 440
491 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:31:31 2016 done: Sat Nov 5 16:31:32 2016
Total Scan time: 8.230 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]