FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5855, 459 aa
  1>>>pF1KB5855 459 - 459 aa - 459 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 10.3291+/-0.000371; mu= -2.8510+/- 0.023
 mean_var=347.9922+/-71.769, 0's: 0 Z-trim(123.8): 7  B-trim: 787 in 1/57
 Lambda= 0.068753
 statistics sampled from 44394 (44402) to 44394 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.814), E-opt: 0.2 (0.521), width:  16
 Scan time: 10.150

The best scores are:                                      opt bits E(85289)
NP_071898 (OMIM: 616014) E3 ubiquitin-protein liga ( 459) 3196 330.5 5.9e-90
XP_016860184 (OMIM: 616014) PREDICTED: E3 ubiquiti ( 347) 2463 257.6 3.7e-68


>>NP_071898 (OMIM: 616014) E3 ubiquitin-protein ligase R  (459 aa)
 initn: 3196 init1: 3196 opt: 3196  Z-score: 1735.9  bits: 330.5 E(85289): 5.9e-90
Smith-Waterman score: 3196; 100.0% identity (100.0% similar) in 459 aa overlap (1-459:1-459)

               10        20        30        40        50        60
pF1KB5 MAASASAAAGEEDWVLPSEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 MAASASAAAGEEDWVLPSEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQ
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 YVCFTLVLQVPAEYPHEVPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 YVCFTLVLQVPAEYPHEVPQISIRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEK
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 GKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQ
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 GKEILTDNNIPHGQCVICLYGFQEKEAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQ
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 EQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEERKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 EQERQHATTKQKAVGVQCPVCREPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEERKR
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 LYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 LYQRQQERGGIIDLEAERNRYFISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAV
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 QSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGEC
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 QSTLPPPLPVATQHICEKIPGTRSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGEC
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB5 HAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRW
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_071 HAPKGTRDTQELPPPEGPLKEPMDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRW
              370       380       390       400       410       420

              430       440       450         
pF1KB5 ERSKGRTPGSSYPRLPRGQGAYRPGTRRESLGLESKDGS
       :::::::::::::::::::::::::::::::::::::::
NP_071 ERSKGRTPGSSYPRLPRGQGAYRPGTRRESLGLESKDGS
              430       440       450         

>>XP_016860184 (OMIM: 616014) PREDICTED: E3 ubiquitin-pr  (347 aa)
 initn: 2463 init1: 2463 opt: 2463  Z-score: 1344.6  bits: 257.6 E(85289): 3.7e-68
Smith-Waterman score: 2463; 100.0% identity (100.0% similar) in 347 aa overlap (113-459:1-347)

             90       100       110       120       130       140  
pF1KB5 IRNPRGLSDEQIHTILQVLGHVAKAGLGTAMLYELIEKGKEILTDNNIPHGQCVICLYGF
                                     ::::::::::::::::::::::::::::::
XP_016                               MLYELIEKGKEILTDNNIPHGQCVICLYGF
                                             10        20        30

            150       160       170       180       190       200  
pF1KB5 QEKEAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQEQERQHATTKQKAVGVQCPVCR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEKEAFTKTPCYHYFHCHCLARYIQHMEQELKAQGQEQEQERQHATTKQKAVGVQCPVCR
               40        50        60        70        80        90

            210       220       230       240       250       260  
pF1KB5 EPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEERKRLYQRQQERGGIIDLEAERNRYF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPLVYDLASLKAAPEPQQPMELYQPSAESLRQQEERKRLYQRQQERGGIIDLEAERNRYF
              100       110       120       130       140       150

            270       280       290       300       310       320  
pF1KB5 ISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ISLQQPPAPAEPESAVDVSKGSQPPSTLAAELSTSPAVQSTLPPPLPVATQHICEKIPGT
              160       170       180       190       200       210

            330       340       350       360       370       380  
pF1KB5 RSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSNQQRLGETQKAMLDPPKPSRGPWRQPERRHPKGGECHAPKGTRDTQELPPPEGPLKEP
              220       230       240       250       260       270

            390       400       410       420       430       440  
pF1KB5 MDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLPRGQGAY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDLKPEPHSQGVEGPPQEKGPGSWQGPPPRRTRDCVRWERSKGRTPGSSYPRLPRGQGAY
              280       290       300       310       320       330

            450         
pF1KB5 RPGTRRESLGLESKDGS
       :::::::::::::::::
XP_016 RPGTRRESLGLESKDGS
              340       




459 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 10:31:43 2016 done: Sat Nov  5 10:31:45 2016
 Total Scan time: 10.150 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]