Result of FASTA (omim) for
pF1KB5841
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5841, 403 aa
1>>>pF1KB5841 403 - 403 aa - 403 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.3434+/-0.000348; mu= -6.0456+/- 0.022
mean_var=269.8035+/-55.329, 0's: 0 Z-trim(123.2): 7 B-trim: 820 in 2/57
Lambda= 0.078082
statistics sampled from 42633 (42640) to 42633 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.804), E-opt: 0.2 (0.5), width: 16
Scan time: 10.460
The best scores are: opt bits E(85289)
NP_001013863 (OMIM: 607881) signal-transducing ada ( 403) 2763 324.1 3.8e-88
NP_060190 (OMIM: 607881) signal-transducing adapto ( 449) 2477 291.9 2.1e-78
XP_011526425 (OMIM: 607881) PREDICTED: signal-tran ( 448) 2475 291.7 2.4e-78
NP_001304698 (OMIM: 604298) signal-transducing ada ( 295) 325 49.4 1.4e-05
NP_036240 (OMIM: 604298) signal-transducing adapto ( 295) 325 49.4 1.4e-05
XP_016863507 (OMIM: 604298) PREDICTED: signal-tran ( 314) 325 49.4 1.5e-05
>>NP_001013863 (OMIM: 607881) signal-transducing adaptor (403 aa)
initn: 2763 init1: 2763 opt: 2763 Z-score: 1703.4 bits: 324.1 E(85289): 3.8e-88
Smith-Waterman score: 2763; 99.8% identity (100.0% similar) in 403 aa overlap (1-403:1-403)
10 20 30 40 50 60
pF1KB5 MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRNQEIKFKVETLECREMWKGFILTVVELR
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_001 EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEPK
310 320 330 340 350 360
370 380 390 400
pF1KB5 VFNGGLGRKLPVSSAQPLFPTAGLADMTAELQKKLEKRRALEH
:::::::::::::::::::::::::::::::::::::::::::
NP_001 VFNGGLGRKLPVSSAQPLFPTAGLADMTAELQKKLEKRRALEH
370 380 390 400
>>NP_060190 (OMIM: 607881) signal-transducing adaptor pr (449 aa)
initn: 2546 init1: 2471 opt: 2477 Z-score: 1528.6 bits: 291.9 E(85289): 2.1e-78
Smith-Waterman score: 2574; 89.2% identity (89.4% similar) in 435 aa overlap (1-389:1-435)
10 20 30 40 50 60
pF1KB5 MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRNQEIKFKVETLECREMWKGFILTVVELR
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
NP_060 EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL
250 260 270 280 290 300
310 320 330 340 350
pF1KB5 PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKP---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPVEK
310 320 330 340 350 360
360 370
pF1KB5 -------------------------------------------EPKVFNGGLGRKLPVSS
:::::::::::::::::
NP_060 GFHHVAQAGLELLTSSDPPTSASQSAGITGVSHHTWPHLSSLPEPKVFNGGLGRKLPVSS
370 380 390 400 410 420
380 390 400
pF1KB5 AQPLFPTAGLADMTAELQKKLEKRRALEH
:::::::::::::::
NP_060 AQPLFPTAGLADMTAELQKKLEKRRALEH
430 440
>>XP_011526425 (OMIM: 607881) PREDICTED: signal-transduc (448 aa)
initn: 2470 init1: 2470 opt: 2475 Z-score: 1527.4 bits: 291.7 E(85289): 2.4e-78
Smith-Waterman score: 2582; 89.4% identity (89.7% similar) in 435 aa overlap (1-390:1-435)
10 20 30 40 50 60
pF1KB5 MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MASALRPPRVPKPKGVLPSHYYESFLEKKGPCDRDYKKFWAGLQGLTIYFYNSNRDFQHV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRNQEIKFKVETLECREMWKGFILTVVELR
::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::::
XP_011 EKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRDQEIKFKVETLECREMWKGFILTVVELR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPTDLTLLPGHLYMMSEVLAKEEARRALETPSCFLKVSRLEAQLLLERYPECGNLLLRPS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDGADGVSVTTRQMHNGTHVVRHYKVKREGPKYVIDVEQPFSCTSLDAVVNYFVSHTKKA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVPFLLDEDYEKVLGYVEADKENGENVWVAPSAPGPGPAPCTGGPKPLSPASSQDKLPPL
250 260 270 280 290 300
310 320 330 340 350
pF1KB5 PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPE--
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPLPNQEENYVTPIGDGPAVDYENQDVASSSWPVILKPKKLPKPPAKLPKPPVGPKPEKG
310 320 330 340 350 360
360 370
pF1KB5 -------------------------------------------PKVFNGGLGRKLPVSSA
:::::::::::::::::
XP_011 FHHVAQAGLELLTSSDPPTSASQSAGITGVSHHTWPHLSSLPEPKVFNGGLGRKLPVSSA
370 380 390 400 410 420
380 390 400
pF1KB5 QPLFPTAGLADMTAELQKKLEKRRALEH
:::::::::::::::
XP_011 QPLFPTAGLADMTAELQKKLEKRRALEH
430 440
>>NP_001304698 (OMIM: 604298) signal-transducing adaptor (295 aa)
initn: 514 init1: 203 opt: 325 Z-score: 221.1 bits: 49.4 E(85289): 1.4e-05
Smith-Waterman score: 516; 33.9% identity (64.3% similar) in 277 aa overlap (4-249:3-272)
10 20 30 40 50
pF1KB5 MASALRPPRVPKPKGVLPSH--------YYESFLEKKGPCDRDYKKFWAGLQGLTIYFYN
: .::. : :. .. . :.:.:: : :.:...:. :.: :..::.
NP_001 MMAKKPPK-PAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYT
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 SNRDFQHVEKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRNQEIKFKVETLECREMWKGF
..... .:.::.. . ::.. .:.. ..:.:.: ..:...:.:. : : :.::
NP_001 DKKSIIYVDKLDIVDLTCLTEQ---NSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGF
60 70 80 90 100 110
120 130 140 150
pF1KB5 ILTVVELRVPTDLTLLPGHLYMMSEVLAKEEARRALET----------------------
::::.:: :: ...::::.. . ::: .:. :: .::
NP_001 ILTVTELSVPQNVSLLPGQVIKLHEVLEREKKRR-IETEQSTSVEKEKEPTEDYVDVLNP
120 130 140 150 160 170
160 170 180 190 200
pF1KB5 -PSCFLKVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKRE
:.:: ::: :: .:.. : ::..:::..:. . :.: :: . .. .::::
NP_001 MPACFYTVSRKEATEMLQKNPSLGNMILRPGSDSRN-YSITIRQEIDIPRI-KHYKVMSV
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB5 GPKYVIDVEQPFSCTSLDAVVNYFVSHTKKALVPFLLDEDYEKVLGYVEADKENGENVWV
: .:.:..:.: . .: .:..:::..:. : ::. . :
NP_001 GQNYTIELEKPVTLPNLFSVIDYFVKETRGNLRPFICSTDENTGQEPSMEGRSEKLKKNP
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB5 APSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVAS
NP_001 HIA
>>NP_036240 (OMIM: 604298) signal-transducing adaptor pr (295 aa)
initn: 514 init1: 203 opt: 325 Z-score: 221.1 bits: 49.4 E(85289): 1.4e-05
Smith-Waterman score: 516; 33.9% identity (64.3% similar) in 277 aa overlap (4-249:3-272)
10 20 30 40 50
pF1KB5 MASALRPPRVPKPKGVLPSH--------YYESFLEKKGPCDRDYKKFWAGLQGLTIYFYN
: .::. : :. .. . :.:.:: : :.:...:. :.: :..::.
NP_036 MMAKKPPK-PAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYT
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 SNRDFQHVEKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRNQEIKFKVETLECREMWKGF
..... .:.::.. . ::.. .:.. ..:.:.: ..:...:.:. : : :.::
NP_036 DKKSIIYVDKLDIVDLTCLTEQ---NSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGF
60 70 80 90 100 110
120 130 140 150
pF1KB5 ILTVVELRVPTDLTLLPGHLYMMSEVLAKEEARRALET----------------------
::::.:: :: ...::::.. . ::: .:. :: .::
NP_036 ILTVTELSVPQNVSLLPGQVIKLHEVLEREKKRR-IETEQSTSVEKEKEPTEDYVDVLNP
120 130 140 150 160 170
160 170 180 190 200
pF1KB5 -PSCFLKVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKRE
:.:: ::: :: .:.. : ::..:::..:. . :.: :: . .. .::::
NP_036 MPACFYTVSRKEATEMLQKNPSLGNMILRPGSDSRN-YSITIRQEIDIPRI-KHYKVMSV
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB5 GPKYVIDVEQPFSCTSLDAVVNYFVSHTKKALVPFLLDEDYEKVLGYVEADKENGENVWV
: .:.:..:.: . .: .:..:::..:. : ::. . :
NP_036 GQNYTIELEKPVTLPNLFSVIDYFVKETRGNLRPFICSTDENTGQEPSMEGRSEKLKKNP
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB5 APSAPGPGPAPCTGGPKPLSPASSQDKLPPLPPLPNQEENYVTPIGDGPAVDYENQDVAS
NP_036 HIA
>>XP_016863507 (OMIM: 604298) PREDICTED: signal-transduc (314 aa)
initn: 389 init1: 203 opt: 325 Z-score: 220.7 bits: 49.4 E(85289): 1.5e-05
Smith-Waterman score: 402; 33.9% identity (63.3% similar) in 221 aa overlap (4-193:3-217)
10 20 30 40 50
pF1KB5 MASALRPPRVPKPKGVLPSH--------YYESFLEKKGPCDRDYKKFWAGLQGLTIYFYN
: .::. : :. .. . :.:.:: : :.:...:. :.: :..::.
XP_016 MMAKKPPK-PAPRRIFQERLKITALPLYFEGFLLIKRSGYREYEHYWTELRGTTLFFYT
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 SNRDFQHVEKLNLGAFEKLTDEIPWGSSRDPGTHFSLILRNQEIKFKVETLECREMWKGF
..... .:.::.. . ::.. .:.. ..:.:.: ..:...:.:. : : :.::
XP_016 DKKSIIYVDKLDIVDLTCLTEQ---NSTEKNCAKFTLVLPKEEVQLKTENTESGEEWRGF
60 70 80 90 100 110
120 130 140 150
pF1KB5 ILTVVELRVPTDLTLLPGHLYMMSEVLAKEEARRALET----------------------
::::.:: :: ...::::.. . ::: .:. :: .::
XP_016 ILTVTELSVPQNVSLLPGQVIKLHEVLEREKKRR-IETEQSTSVEKEKEPTEDYVDVLNP
120 130 140 150 160 170
160 170 180 190 200
pF1KB5 -PSCFLKVSRLEAQLLLERYPECGNLLLRPSGDGADGVSVTTRQMHNGTHVVRHYKVKRE
:.:: ::: :: .:.. : ::..:::..:. . :.: ::
XP_016 MPACFYTVSRKEATEMLQKNPSLGNMILRPGSDSRN-YSITIRQEIDFAIDDDDDDDDDD
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB5 GPKYVIDVEQPFSCTSLDAVVNYFVSHTKKALVPFLLDEDYEKVLGYVEADKENGENVWV
XP_016 DDMMSFFCCCCCFLFLFFLRRGLALSHRLEYSGASSAHCHLRLPGSRHSPASASRVAGTT
240 250 260 270 280 290
403 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 15:08:58 2016 done: Sat Nov 5 15:08:59 2016
Total Scan time: 10.460 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]