Result of FASTA (omim) for
pF1KB5813
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5813, 474 aa
1>>>pF1KB5813 474 - 474 aa - 474 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.4454+/-0.00031; mu= 10.7590+/- 0.020
mean_var=199.3792+/-40.875, 0's: 0 Z-trim(123.2): 62 B-trim: 0 in 0/53
Lambda= 0.090831
statistics sampled from 42533 (42622) to 42533 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.802), E-opt: 0.2 (0.5), width: 16
Scan time: 10.610
The best scores are: opt bits E(85289)
NP_036248 (OMIM: 608453) E3 ubiquitin-protein liga ( 474) 3339 449.7 7.9e-126
XP_011524990 (OMIM: 608453) PREDICTED: E3 ubiquiti ( 493) 3206 432.3 1.4e-120
XP_005258753 (OMIM: 608453) PREDICTED: E3 ubiquiti ( 431) 3003 405.7 1.3e-112
NP_001124324 (OMIM: 608453) E3 ubiquitin-protein l ( 428) 1832 252.2 2.1e-66
XP_011524991 (OMIM: 608453) PREDICTED: E3 ubiquiti ( 447) 1832 252.2 2.1e-66
XP_011524992 (OMIM: 608453) PREDICTED: E3 ubiquiti ( 283) 1509 209.7 8.6e-54
NP_001308727 (OMIM: 604491) E3 ubiquitin-protein l ( 889) 1408 197.0 1.8e-49
NP_001308726 (OMIM: 604491) E3 ubiquitin-protein l ( 889) 1408 197.0 1.8e-49
XP_011511561 (OMIM: 604491) PREDICTED: E3 ubiquiti ( 894) 1408 197.0 1.8e-49
NP_001308724 (OMIM: 604491) E3 ubiquitin-protein l ( 933) 1408 197.0 1.9e-49
NP_001308723 (OMIM: 604491) E3 ubiquitin-protein l ( 933) 1408 197.0 1.9e-49
NP_001308720 (OMIM: 604491) E3 ubiquitin-protein l ( 938) 1408 197.0 1.9e-49
NP_001308722 (OMIM: 604491) E3 ubiquitin-protein l ( 938) 1408 197.0 1.9e-49
NP_001308719 (OMIM: 604491) E3 ubiquitin-protein l ( 960) 1408 197.0 1.9e-49
NP_001308718 (OMIM: 604491) E3 ubiquitin-protein l ( 961) 1408 197.0 1.9e-49
XP_016862885 (OMIM: 604491) PREDICTED: E3 ubiquiti ( 966) 1408 197.0 1.9e-49
XP_011511559 (OMIM: 604491) PREDICTED: E3 ubiquiti ( 982) 1408 197.0 1.9e-49
NP_001308717 (OMIM: 604491) E3 ubiquitin-protein l ( 982) 1408 197.0 1.9e-49
NP_733762 (OMIM: 604491) E3 ubiquitin-protein liga ( 982) 1408 197.0 1.9e-49
XP_016862884 (OMIM: 604491) PREDICTED: E3 ubiquiti (1004) 1408 197.0 2e-49
NP_001308715 (OMIM: 604491) E3 ubiquitin-protein l (1010) 1408 197.0 2e-49
XP_011541359 (OMIM: 165360,607785,613563) PREDICTE ( 501) 1367 191.3 5.1e-48
NP_005179 (OMIM: 165360,607785,613563) E3 ubiquiti ( 906) 1367 191.6 7.6e-48
XP_016874000 (OMIM: 165360,607785,613563) PREDICTE ( 746) 1246 175.7 3.9e-43
NP_001308728 (OMIM: 604491) E3 ubiquitin-protein l ( 889) 1147 162.8 3.6e-39
XP_016862889 (OMIM: 604491) PREDICTED: E3 ubiquiti ( 917) 1147 162.8 3.6e-39
NP_001308725 (OMIM: 604491) E3 ubiquitin-protein l ( 933) 1147 162.8 3.7e-39
XP_016862888 (OMIM: 604491) PREDICTED: E3 ubiquiti ( 933) 1147 162.8 3.7e-39
XP_016862887 (OMIM: 604491) PREDICTED: E3 ubiquiti ( 955) 1147 162.8 3.7e-39
XP_016862886 (OMIM: 604491) PREDICTED: E3 ubiquiti ( 961) 1147 162.8 3.8e-39
NP_001308745 (OMIM: 604491) E3 ubiquitin-protein l ( 629) 822 120.0 1.9e-26
NP_001308740 (OMIM: 604491) E3 ubiquitin-protein l ( 673) 822 120.1 2e-26
NP_001308742 (OMIM: 604491) E3 ubiquitin-protein l ( 673) 822 120.1 2e-26
NP_001308737 (OMIM: 604491) E3 ubiquitin-protein l ( 678) 822 120.1 2e-26
NP_001308735 (OMIM: 604491) E3 ubiquitin-protein l ( 722) 822 120.1 2e-26
NP_001308736 (OMIM: 604491) E3 ubiquitin-protein l ( 722) 822 120.1 2e-26
>>NP_036248 (OMIM: 608453) E3 ubiquitin-protein ligase C (474 aa)
initn: 3339 init1: 3339 opt: 3339 Z-score: 2380.0 bits: 449.7 E(85289): 7.9e-126
Smith-Waterman score: 3339; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
430 440 450 460 470
>>XP_011524990 (OMIM: 608453) PREDICTED: E3 ubiquitin-pr (493 aa)
initn: 3206 init1: 3206 opt: 3206 Z-score: 2285.6 bits: 432.3 E(85289): 1.4e-120
Smith-Waterman score: 3206; 99.8% identity (99.8% similar) in 457 aa overlap (1-457:1-457)
10 20 30 40 50 60
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
:::::::::::::::::::::::::::::::::: ::
XP_011 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVALLALPRLRAPLLLPRIKAVASAAQE
430 440 450 460 470 480
XP_011 ATSSPQVVWDSQV
490
>>XP_005258753 (OMIM: 608453) PREDICTED: E3 ubiquitin-pr (431 aa)
initn: 3003 init1: 3003 opt: 3003 Z-score: 2142.5 bits: 405.7 E(85289): 1.3e-112
Smith-Waterman score: 3003; 100.0% identity (100.0% similar) in 428 aa overlap (1-428:1-428)
10 20 30 40 50 60
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
::::::::
XP_005 GRELELGQNSA
430
>>NP_001124324 (OMIM: 608453) E3 ubiquitin-protein ligas (428 aa)
initn: 1857 init1: 1822 opt: 1832 Z-score: 1313.3 bits: 252.2 E(85289): 2.1e-66
Smith-Waterman score: 2924; 90.3% identity (90.3% similar) in 474 aa overlap (1-474:1-428)
10 20 30 40 50 60
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
:::::::::::::::::::::
NP_001 FLTYDEVQERLQACRDKPGSY---------------------------------------
250 260
310 320 330 340 350 360
pF1KB5 GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -------LYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
270 280 290 300 310
370 380 390 400 410 420
pF1KB5 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
320 330 340 350 360 370
430 440 450 460 470
pF1KB5 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
380 390 400 410 420
>>XP_011524991 (OMIM: 608453) PREDICTED: E3 ubiquitin-pr (447 aa)
initn: 1884 init1: 1822 opt: 1832 Z-score: 1313.0 bits: 252.2 E(85289): 2.1e-66
Smith-Waterman score: 2791; 89.7% identity (89.7% similar) in 457 aa overlap (1-457:1-411)
10 20 30 40 50 60
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
:::::::::::::::::::::
XP_011 FLTYDEVQERLQACRDKPGSY---------------------------------------
250 260
310 320 330 340 350 360
pF1KB5 GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 -------LYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
270 280 290 300 310
370 380 390 400 410 420
pF1KB5 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
320 330 340 350 360 370
430 440 450 460 470
pF1KB5 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
:::::::::::::::::::::::::::::::::: ::
XP_011 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVALLALPRLRAPLLLPRIKAVASAAQE
380 390 400 410 420 430
XP_011 ATSSPQVVWDSQV
440
>>XP_011524992 (OMIM: 608453) PREDICTED: E3 ubiquitin-pr (283 aa)
initn: 1509 init1: 1509 opt: 1509 Z-score: 1086.7 bits: 209.7 E(85289): 8.6e-54
Smith-Waterman score: 1509; 100.0% identity (100.0% similar) in 219 aa overlap (1-219:1-219)
10 20 30 40 50 60
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
:::::::::::::::::::::::::::::::::::::::
XP_011 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQLHLPAQLYSPGAVGHRLCELR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
XP_011 WQHPADHPCQQTPVPGAPGGTEGRLVSLHSATSTQMERPTTQT
250 260 270 280
>>NP_001308727 (OMIM: 604491) E3 ubiquitin-protein ligas (889 aa)
initn: 1427 init1: 1310 opt: 1408 Z-score: 1009.1 bits: 197.0 E(85289): 1.8e-49
Smith-Waterman score: 1408; 49.4% identity (76.4% similar) in 403 aa overlap (4-404:32-426)
10 20 30
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCV
::.: . . :.. .. ...... . :
NP_001 ANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 DPRLSV--SPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKS
.:.:.. ::: . :.:: : : :: . . . . . .... ::. .: ::
NP_001 NPKLQLKNSPPYILDILPDTYQHLRLILSKY---DDNQKLAQLSENEYFKIYIDSLMKKS
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 RQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQL
... :. . ....... :. ::.:.::..::::: ::..:.::.:.. : ...
NP_001 KRAIRLF-----KEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRI
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 TKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEF
::: : :::. : . ..:: :.. : : . : :.::..::::::. ..:.:::
NP_001 TKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 DVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLG
:.:::::::: ..:.::..:::.:::::::::::::. ::: :::::::: ::::::
NP_001 DIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 QWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRI
:::::::..::.:::::: :::: :.:..:...::::::::...::::: : . :...:
NP_001 QWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHI
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 HVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRC
.:..:: .:: : :::.:::::::..:::::::::::.:. ::.:::.::.: ::::::
NP_001 KVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRC
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB5 EIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQ
:::: : . . :
NP_001 EIKGTEPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDR
420 430 440 450 460 470
>>NP_001308726 (OMIM: 604491) E3 ubiquitin-protein ligas (889 aa)
initn: 1427 init1: 1310 opt: 1408 Z-score: 1009.1 bits: 197.0 E(85289): 1.8e-49
Smith-Waterman score: 1408; 49.4% identity (76.4% similar) in 403 aa overlap (4-404:32-426)
10 20 30
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCV
::.: . . :.. .. ...... . :
NP_001 ANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 DPRLSV--SPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKS
.:.:.. ::: . :.:: : : :: . . . . . .... ::. .: ::
NP_001 NPKLQLKNSPPYILDILPDTYQHLRLILSKY---DDNQKLAQLSENEYFKIYIDSLMKKS
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 RQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQL
... :. . ....... :. ::.:.::..::::: ::..:.::.:.. : ...
NP_001 KRAIRLF-----KEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRI
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 TKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEF
::: : :::. : . ..:: :.. : : . : :.::..::::::. ..:.:::
NP_001 TKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 DVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLG
:.:::::::: ..:.::..:::.:::::::::::::. ::: :::::::: ::::::
NP_001 DIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 QWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRI
:::::::..::.:::::: :::: :.:..:...::::::::...::::: : . :...:
NP_001 QWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHI
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 HVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRC
.:..:: .:: : :::.:::::::..:::::::::::.:. ::.:::.::.: ::::::
NP_001 KVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRC
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB5 EIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQ
:::: : . . :
NP_001 EIKGTEPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDR
420 430 440 450 460 470
>>XP_011511561 (OMIM: 604491) PREDICTED: E3 ubiquitin-pr (894 aa)
initn: 1427 init1: 1310 opt: 1408 Z-score: 1009.1 bits: 197.0 E(85289): 1.8e-49
Smith-Waterman score: 1408; 49.4% identity (76.4% similar) in 403 aa overlap (4-404:60-454)
10 20 30
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCV
::.: . . :.. .. ...... . :
XP_011 ANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQ
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB5 DPRLSV--SPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKS
.:.:.. ::: . :.:: : : :: . . . . . .... ::. .: ::
XP_011 NPKLQLKNSPPYILDILPDTYQHLRLILSKY---DDNQKLAQLSENEYFKIYIDSLMKKS
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB5 RQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQL
... :. . ....... :. ::.:.::..::::: ::..:.::.:.. : ...
XP_011 KRAIRLF-----KEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRI
150 160 170 180 190 200
160 170 180 190 200 210
pF1KB5 TKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEF
::: : :::. : . ..:: :.. : : . : :.::..::::::. ..:.:::
XP_011 TKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEF
210 220 230 240 250 260
220 230 240 250 260 270
pF1KB5 DVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLG
:.:::::::: ..:.::..:::.:::::::::::::. ::: :::::::: ::::::
XP_011 DIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLG
270 280 290 300 310 320
280 290 300 310 320 330
pF1KB5 QWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRI
:::::::..::.:::::: :::: :.:..:...::::::::...::::: : . :...:
XP_011 QWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHI
330 340 350 360 370 380
340 350 360 370 380 390
pF1KB5 HVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRC
.:..:: .:: : :::.:::::::..:::::::::::.:. ::.:::.::.: ::::::
XP_011 KVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRC
390 400 410 420 430 440
400 410 420 430 440 450
pF1KB5 EIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQ
:::: : . . :
XP_011 EIKGTEPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDR
450 460 470 480 490 500
>>NP_001308724 (OMIM: 604491) E3 ubiquitin-protein ligas (933 aa)
initn: 1427 init1: 1310 opt: 1408 Z-score: 1008.9 bits: 197.0 E(85289): 1.9e-49
Smith-Waterman score: 1408; 49.4% identity (76.4% similar) in 403 aa overlap (4-404:32-426)
10 20 30
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCV
::.: . . :.. .. ...... . :
NP_001 ANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 DPRLSV--SPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKS
.:.:.. ::: . :.:: : : :: . . . . . .... ::. .: ::
NP_001 NPKLQLKNSPPYILDILPDTYQHLRLILSKY---DDNQKLAQLSENEYFKIYIDSLMKKS
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 RQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQL
... :. . ....... :. ::.:.::..::::: ::..:.::.:.. : ...
NP_001 KRAIRLF-----KEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRI
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 TKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEF
::: : :::. : . ..:: :.. : : . : :.::..::::::. ..:.:::
NP_001 TKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 DVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLG
:.:::::::: ..:.::..:::.:::::::::::::. ::: :::::::: ::::::
NP_001 DIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 QWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRI
:::::::..::.:::::: :::: :.:..:...::::::::...::::: : . :...:
NP_001 QWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHI
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 HVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRC
.:..:: .:: : :::.:::::::..:::::::::::.:. ::.:::.::.: ::::::
NP_001 KVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRC
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB5 EIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQ
:::: : . . :
NP_001 EIKGTEPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDR
420 430 440 450 460 470
474 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:57:29 2016 done: Sat Nov 5 14:57:31 2016
Total Scan time: 10.610 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]