Result of FASTA (ccds) for
pF1KB5813
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5813, 474 aa
1>>>pF1KB5813 474 - 474 aa - 474 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3982+/-0.000755; mu= 11.2448+/- 0.046
mean_var=192.0077+/-39.494, 0's: 0 Z-trim(116.0): 28 B-trim: 5 in 1/51
Lambda= 0.092558
statistics sampled from 16530 (16556) to 16530 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.809), E-opt: 0.2 (0.509), width: 16
Scan time: 3.860
The best scores are: opt bits E(32554)
CCDS12643.1 CBLC gene_id:23624|Hs108|chr19 ( 474) 3339 457.9 1.1e-128
CCDS46109.1 CBLC gene_id:23624|Hs108|chr19 ( 428) 1832 256.6 3.8e-68
CCDS2948.1 CBLB gene_id:868|Hs108|chr3 ( 982) 1408 200.3 7.4e-51
CCDS8418.1 CBL gene_id:867|Hs108|chr11 ( 906) 1367 194.8 3.1e-49
>>CCDS12643.1 CBLC gene_id:23624|Hs108|chr19 (474 aa)
initn: 3339 init1: 3339 opt: 3339 Z-score: 2423.9 bits: 457.9 E(32554): 1.1e-128
Smith-Waterman score: 3339; 100.0% identity (100.0% similar) in 474 aa overlap (1-474:1-474)
10 20 30 40 50 60
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
370 380 390 400 410 420
430 440 450 460 470
pF1KB5 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
430 440 450 460 470
>>CCDS46109.1 CBLC gene_id:23624|Hs108|chr19 (428 aa)
initn: 1857 init1: 1822 opt: 1832 Z-score: 1336.9 bits: 256.6 E(32554): 3.8e-68
Smith-Waterman score: 2924; 90.3% identity (90.3% similar) in 474 aa overlap (1-474:1-428)
10 20 30 40 50 60
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSVSPPSLRDLLPRTAQLLREVAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 SRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDELFRAGSRLRRQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 LAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVLPWAEFESLLG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 TCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQLLAVNHPGYMA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPANKPLSQVLLE
:::::::::::::::::::::
CCDS46 FLTYDEVQERLQACRDKPGSY---------------------------------------
250 260
310 320 330 340 350 360
pF1KB5 GQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
:::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 -------LYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFELCKICAESNKD
270 280 290 300 310
370 380 390 400 410 420
pF1KB5 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 VKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQFHGQATAEDSGNSSDQE
320 330 340 350 360 370
430 440 450 460 470
pF1KB5 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS46 GRELELGQVPLSAPPLPPRPDLPPRKPRNAQPKVRLLKGNSPPAALGPQDPAPA
380 390 400 410 420
>>CCDS2948.1 CBLB gene_id:868|Hs108|chr3 (982 aa)
initn: 1427 init1: 1310 opt: 1408 Z-score: 1026.5 bits: 200.3 E(32554): 7.4e-51
Smith-Waterman score: 1408; 49.4% identity (76.4% similar) in 403 aa overlap (4-404:32-426)
10 20 30
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCV
::.: . . :.. .. ...... . :
CCDS29 ANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB5 DPRLSV--SPPSLRDLLPRTAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKS
.:.:.. ::: . :.:: : : :: . . . . . .... ::. .: ::
CCDS29 NPKLQLKNSPPYILDILPDTYQHLRLILSKY---DDNQKLAQLSENEYFKIYIDSLMKKS
70 80 90 100 110
100 110 120 130 140 150
pF1KB5 RQVAALLPPRGRRSANDELFRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQL
... :. . ....... :. ::.:.::..::::: ::..:.::.:.. : ...
CCDS29 KRAIRLF-----KEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRI
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB5 TKAPAHTFWRESCGARCVLPWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEF
::: : :::. : . ..:: :.. : : . : :.::..::::::. ..:.:::
CCDS29 TKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEF
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB5 DVFTRLFQPWPTLLKNWQLLAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLG
:.:::::::: ..:.::..:::.:::::::::::::. ::: :::::::: ::::::
CCDS29 DIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB5 QWAIGYVSSDGSILQTIPANKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRI
:::::::..::.:::::: :::: :.:..:...::::::::...::::: : . :...:
CCDS29 QWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDHI
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB5 HVSEEQLQLYWAMDSTFELCKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRC
.:..:: .:: : :::.:::::::..:::::::::::.:. ::.:::.::.: ::::::
CCDS29 KVTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTAWQESDGQGCPFCRC
360 370 380 390 400 410
400 410 420 430 440 450
pF1KB5 EIKGWEAVSIYQFHGQATAEDSGNSSDQEGRELELGQVPLSAPPLPPRPDLPPRKPRNAQ
:::: : . . :
CCDS29 EIKGTEPIIVDPFDPRDEGSRCCSIIDPFGMPMLDLDDDDDREESLMMNRLANVRKCTDR
420 430 440 450 460 470
>>CCDS8418.1 CBL gene_id:867|Hs108|chr11 (906 aa)
initn: 1442 init1: 1307 opt: 1367 Z-score: 997.3 bits: 194.8 E(32554): 3.1e-49
Smith-Waterman score: 1449; 46.6% identity (71.3% similar) in 474 aa overlap (23-472:61-522)
10 20 30 40 50
pF1KB5 MALAVAPWGRQWEEARALGRAVRMLQRLEEQCVDPRLSV--SPPSLRDLLPR
...... . : .:.:.. ::: . ::::
CCDS84 DAFQPHHHHHHHLSPHPPGTVDKKMVEKCWKLMDKVVRLCQNPKLALKNSPPYILDLLPD
40 50 60 70 80 90
60 70 80 90 100 110
pF1KB5 TAQLLREVAHSRRAAGGGGPGGPGGSGDFLLIYLANLEAKSRQVAALLPPRGRRSANDEL
: : :: . :: : : .... ... :: :..:. .:. . .....
CCDS84 TYQHLRTIL-SRYE----GKMETLGENEYFRVFMENLMKKTKQTISLF-----KEGKERM
100 110 120 130 140
120 130 140 150 160 170
pF1KB5 FRAGSRLRRQLAKLAIIFSHMHAELHALFPGGKYCGHMYQLTKAPAHTFWRESCGARCVL
.. .:. ::.:.::..::::: :::...::.: . : ...::: : :::.. : . ..
CCDS84 YEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRITKADAAEFWRKAFGEKTIV
150 160 170 180 190 200
180 190 200 210 220 230
pF1KB5 PWAEFESLLGTCHPVEPGCTALALRTTIDLTCSGHVSIFEFDVFTRLFQPWPTLLKNWQL
:: :.. : ::. : :.::..::::::. ..:.::::.:::::::: .::.::.
CCDS84 PWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWSSLLRNWNS
210 220 230 240 250 260
240 250 260 270 280 290
pF1KB5 LAVNHPGYMAFLTYDEVQERLQACRDKPGSYIFRPSCTRLGQWAIGYVSSDGSILQTIPA
:::.:::::::::::::. ::: :::::::: :::::::::::::..::.::::::
CCDS84 LAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQWAIGYVTADGNILQTIPH
270 280 290 300 310 320
300 310 320 330 340 350
pF1KB5 NKPLSQVLLEGQKDGFYLYPDGKTHNPDLTELGQAEPQQRIHVSEEQLQLYWAMDSTFEL
:::: :.:..: ..::::.:::...::::: : . ::..:.:..:: .:: : :::.:
CCDS84 NKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIKVTQEQYELYCEMGSTFQL
330 340 350 360 370 380
360 370 380 390 400
pF1KB5 CKICAESNKDVKIEPCGHLLCSCCLAAWQHSDSQTCPFCRCEIKGWEAVSIYQF------
::::::..:::::::::::.:. ::..::.:..: :::::::::: : . . :
CCDS84 CKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCEIKGTEPIVVDPFDPRGSG
390 400 410 420 430 440
410 420 430 440
pF1KB5 ----HGQATAEDSGNSSDQEGRE-------LELGQVPLSAPPLP----PRPDLPPRKPR-
.: : . . ..:.. : ::. . . :: : :. .::: ::
CCDS84 SLLRQGAEGAPSPNYDDDDDERADDTLFMMKELAGAKVERPPSPFSMAPQASLPPVPPRL
450 460 470 480 490 500
450 460 470
pF1KB5 NAQPKVRLLKGNSPPAALGPQDPAPA
. :. :. .: .::: . :
CCDS84 DLLPQ-RVCVPSSA-SALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVGAES
510 520 530 540 550
474 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 14:57:28 2016 done: Sat Nov 5 14:57:29 2016
Total Scan time: 3.860 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]