Result of FASTA (omim) for
pF1KB5675
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5675, 1011 aa
1>>>pF1KB5675 1011 - 1011 aa - 1011 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2916+/-0.000396; mu= 22.3594+/- 0.025
mean_var=81.1851+/-16.618, 0's: 0 Z-trim(112.9): 19 B-trim: 9 in 2/54
Lambda= 0.142343
statistics sampled from 22052 (22066) to 22052 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.618), E-opt: 0.2 (0.259), width: 16
Scan time: 14.210
The best scores are: opt bits E(85289)
NP_000519 (OMIM: 248500,609458) lysosomal alpha-ma (1011) 6945 1436.8 0
XP_005259970 (OMIM: 248500,609458) PREDICTED: lyso (1012) 6933 1434.4 0
NP_001166969 (OMIM: 248500,609458) lysosomal alpha (1010) 6926 1432.9 0
XP_016882307 (OMIM: 248500,609458) PREDICTED: lyso ( 644) 4361 906.0 0
NP_006113 (OMIM: 600988) alpha-mannosidase 2x isof (1150) 478 108.8 1.7e-22
XP_016877674 (OMIM: 600988) PREDICTED: alpha-manno (1150) 478 108.8 1.7e-22
XP_005254967 (OMIM: 600988) PREDICTED: alpha-manno (1175) 478 108.9 1.7e-22
XP_016877673 (OMIM: 600988) PREDICTED: alpha-manno (1175) 478 108.9 1.7e-22
NP_001307906 (OMIM: 600988) alpha-mannosidase 2x i (1175) 478 108.9 1.7e-22
XP_011541697 (OMIM: 154582) PREDICTED: alpha-manno ( 884) 458 104.6 2.4e-21
XP_016864961 (OMIM: 154582) PREDICTED: alpha-manno (1095) 458 104.7 2.8e-21
NP_002363 (OMIM: 154582) alpha-mannosidase 2 [Homo (1144) 458 104.7 2.9e-21
XP_011519868 (OMIM: 600988) PREDICTED: alpha-manno ( 729) 312 74.6 2.2e-12
XP_011519867 (OMIM: 600988) PREDICTED: alpha-manno ( 754) 287 69.5 8e-11
>>NP_000519 (OMIM: 248500,609458) lysosomal alpha-mannos (1011 aa)
initn: 6945 init1: 6945 opt: 6945 Z-score: 7703.0 bits: 1436.8 E(85289): 0
Smith-Waterman score: 6945; 99.8% identity (99.9% similar) in 1011 aa overlap (1-1011:1-1011)
10 20 30 40 50 60
pF1KB5 MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 IAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 ASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TAQGRYYRTNHIVMTMGSDFQYENANMWFKNLDKLIQLVNAQQAKGSSVHVLYSTPACYL
::::::::::: ::::::::::::::::::::::::.:::::::::::::::::::::::
NP_000 TAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQQAKGSSVHVLYSTPACYL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 WELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 LAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNAL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 ARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 ARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDP
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 NGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 WSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAY
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNT
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 RIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRG
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 RHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB5 HLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQ
910 920 930 940 950 960
970 980 990 1000 1010
pF1KB5 LREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG
970 980 990 1000 1010
>>XP_005259970 (OMIM: 248500,609458) PREDICTED: lysosoma (1012 aa)
initn: 4564 init1: 4564 opt: 6933 Z-score: 7689.6 bits: 1434.4 E(85289): 0
Smith-Waterman score: 6933; 99.7% identity (99.8% similar) in 1012 aa overlap (1-1011:1-1012)
10 20 30 40 50 60
pF1KB5 MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 IAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 ASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVA
250 260 270 280 290 300
310 320 330 340 350
pF1KB5 TAQGRYYRTNHIVMTMGSDFQYENANMWFKNLDKLIQLVNAQQ-AKGSSVHVLYSTPACY
::::::::::: ::::::::::::::::::::::::.:::::: ::::::::::::::::
XP_005 TAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQQQAKGSSVHVLYSTPACY
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 LWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 GLAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GLAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB5 LARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKD
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB5 PNGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRR
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB5 SWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGA
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB5 YIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPI
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB5 PVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVN
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB5 TRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVR
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB5 GRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPS
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB5 VHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVAN
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB5 QLREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QLREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG
970 980 990 1000 1010
>>NP_001166969 (OMIM: 248500,609458) lysosomal alpha-man (1010 aa)
initn: 4557 init1: 4557 opt: 6926 Z-score: 7681.9 bits: 1432.9 E(85289): 0
Smith-Waterman score: 6926; 99.7% identity (99.8% similar) in 1011 aa overlap (1-1011:1-1010)
10 20 30 40 50 60
pF1KB5 MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGAYARASGVCARGCLDSAGPWTMSRALRPPLPPLCFFLLLLAAAGARAGGYETCPTVQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 NMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDIQHAGVQYILDSVISALLADPTRRFIYVE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 IAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IAFFSRWWHQQTNATQEVVRDLVRQGRLEFANGGWVMNDEAATHYGAIVDQMTLGLRFLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTFGNDGRPRVAWHIDPFGHSREQASLFAQMGFDGFFFGRLDYQDKWVRMQKLEMEQVWR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 ASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASTSLKPPTADLFTGVLPNGYNPPRNLCWDVLCVDQPLVEDPRSPEYNAKELVDYFLNVA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 TAQGRYYRTNHIVMTMGSDFQYENANMWFKNLDKLIQLVNAQQAKGSSVHVLYSTPACYL
::::::::::: ::::::::::::::::::::::::.::::: :::::::::::::::::
NP_001 TAQGRYYRTNHTVMTMGSDFQYENANMWFKNLDKLIRLVNAQ-AKGSSVHVLYSTPACYL
310 320 330 340 350
370 380 390 400 410 420
pF1KB5 WELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVG
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB5 LAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNAL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KB5 ARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGRKVNWMVRLPVSEGVFVVKDP
480 490 500 510 520 530
550 560 570 580 590 600
pF1KB5 NGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSVAQVPRWKPQARAPQPIPRRS
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB5 WSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAY
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB5 IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIP
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB5 VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNT
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB5 RIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRG
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB5 RHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB5 HLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLRDLFSTFTITRLQETTLVANQ
900 910 920 930 940 950
970 980 990 1000 1010
pF1KB5 LREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG
960 970 980 990 1000 1010
>>XP_016882307 (OMIM: 248500,609458) PREDICTED: lysosoma (644 aa)
initn: 4361 init1: 4361 opt: 4361 Z-score: 4837.8 bits: 906.0 E(85289): 0
Smith-Waterman score: 4361; 100.0% identity (100.0% similar) in 641 aa overlap (371-1011:4-644)
350 360 370 380 390 400
pF1KB5 AQQAKGSSVHVLYSTPACYLWELNKANLTWSVKHDDFFPYADGPHQFWTGYFSSRPALKR
::::::::::::::::::::::::::::::
XP_016 MRRSVKHDDFFPYADGPHQFWTGYFSSRPALKR
10 20 30
410 420 430 440 450 460
pF1KB5 YERLSYNFLQVCNQLEALVGLAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVAND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YERLSYNFLQVCNQLEALVGLAANVGPYGSGDSAPLNEAMAVLQHHDAVSGTSRQHVAND
40 50 60 70 80 90
470 480 490 500 510 520
pF1KB5 YARQLAAGWGPCEVLLSNALARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YARQLAAGWGPCEVLLSNALARLRGFKDHFTFCQQLNISICPLSQTAARFQVIVYNPLGR
100 110 120 130 140 150
530 540 550 560 570 580
pF1KB5 KVNWMVRLPVSEGVFVVKDPNGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVNWMVRLPVSEGVFVVKDPNGRTVPSDVVIFPSSDSQAHPPELLFSASLPALGFSTYSV
160 170 180 190 200 210
590 600 610 620 630 640
pF1KB5 AQVPRWKPQARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQVPRWKPQARAPQPIPRRSWSPALTIENEHIRATFDPDTGLLMEIMNMNQQLLLPVRQT
220 230 240 250 260 270
650 660 670 680 690 700
pF1KB5 FFWYNASIGDNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FFWYNASIGDNESDQASGAYIFRPNQQKPLPVSRWAQIHLVKTPLVQEVHQNFSAWCSQV
280 290 300 310 320 330
710 720 730 740 750 760
pF1KB5 VRLYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VRLYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDSNGREILERRRDYR
340 350 360 370 380 390
770 780 790 800 810 820
pF1KB5 PTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQGGSSLRDGSLELMVHRRLLKD
400 410 420 430 440 450
830 840 850 860 870 880
pF1KB5 DGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLAEQEVLAPQVVLAPGGGAAYN
460 470 480 490 500 510
890 900 910 920 930 940
pF1KB5 LGAPPRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGAPPRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQFAVGEDSGRNLSAPVTLNLR
520 530 540 550 560 570
950 960 970 980 990 1000
pF1KB5 DLFSTFTITRLQETTLVANQLREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLFSTFTITRLQETTLVANQLREAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTF
580 590 600 610 620 630
1010
pF1KB5 LASVQWKEVDG
:::::::::::
XP_016 LASVQWKEVDG
640
>>NP_006113 (OMIM: 600988) alpha-mannosidase 2x isoform (1150 aa)
initn: 900 init1: 302 opt: 478 Z-score: 524.8 bits: 108.8 E(85289): 1.7e-22
Smith-Waterman score: 1058; 28.6% identity (55.9% similar) in 984 aa overlap (63-956:166-1120)
40 50 60 70 80 90
pF1KB5 PPLCFFLLLLAAAGARAGGYETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDI
:.: ..::.:.: ::.:: :.:. ..
NP_006 EELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGWIKTFDKYY---TEQT
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB5 QHAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFAN
:: ::.:..: : :: :::...:..::..:: . . . .:: :: .:.::.:.
NP_006 QH-----ILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGNGQLEIAT
200 210 220 230 240
160 170 180 190 200 210
pF1KB5 GGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMG
::::: ::: .:: :..::. : ..:: ..: . :: .: .::::.: . :. . .
NP_006 GGWVMPDEANSHYFALIDQLIEGHQWLERNLG--ATPRSGWAVDPFGYSSTMPYLLRRAN
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB5 FDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLP-NGYNPPRNLCWD-
. .... :. : : .: .:: . . . ..:.: ..: .:. :.. :
NP_006 LTSMLIQRVHYAIKKHFAATHSLEFMWRQTWD-SDSSTDIFCHMMPFYSYDVPHTCGPDP
310 320 330 340 350 360
280 290 300 310
pF1KB5 -VLC-----------VDQPLVEDPRS-PEYNAKELVDYFLNVATAQGRYYRTNHIVMTMG
. : .. : ::. : :. : . .:. ... .:.: ... .:
NP_006 KICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLLVPLG
370 380 390 400 410 420
320 330 340 350 360
pF1KB5 SDFQYENANMW---FKNLDKLIQLVNAQQAKGSSVHVLYSTPACYLWELNKANLT-----
.::.:.. . : : : ..:... :.. . :.. ..: . :. : : . .
NP_006 DDFRYDKPQEWDAQFFNYQRLFDFFNSR--PNLHVQAQFGTLSDYFDALYKRTGVEPGAR
430 440 450 460 470 480
370 380 390 400 410 420
pF1KB5 ---WSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVGLAAN--
. : ::: ::: ..::::..::: : .:. :. . : .:.. :
NP_006 PPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHARRS
490 500 510 520 530 540
430 440 450 460 470
pF1KB5 --VGPYGSGDSAPLNEA---MAVLQHHDAVSGTSRQHVANDYA-RQLAAGWGPCEVLLSN
.: : .: . :.:: ....:::::..::... :. ::. : : . . .:..
NP_006 GLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVIIHA
550 560 570 580 590 600
480 490 500 510 520
pF1KB5 ALARLRGFKDHFTFCQQ---LNISICPLSQTA------------ARFQVIVYNPLGRKVN
: . : :. . : . :... ::. : :: :...::: ..
NP_006 AHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRF-VVLFNPLEQERF
610 620 630 640 650 660
530 540 550 560 570 580
pF1KB5 WMVRLPVSEGVFVVKDPNGRTVPSDVVIFPSSDSQAHPPELLFSAS--LPALGFSTYSVA
:: : :. : . .:. . .. :: ..: : :. :::::... ..
NP_006 SMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQLQ
670 680 690 700 710 720
590 600 610 620
pF1KB5 -------QVP---RWKPQARA-----PQPIPRR---SWSPALTIENEHIRATFDPDTGLL
.: : ..: . .: : : . ... :..... :. ::::
NP_006 LGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLL
730 740 750 760 770 780
630 640 650 660 670 680
pF1KB5 MEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAYIFRPN-QQKPLPVSRWAQIHLVK
: .... : . . : : : . ::::.: :. . :: .. .....
NP_006 KSIRRVDEEHEQQVDMQVLVY----GTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTE
790 800 810 820 830
690 700 710 720 730 740
pF1KB5 TPLVQEVHQNFSAWCSQVVRLY--PGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETK
:. .:: . :.:::: :: . : :. : . . . : .::. .. : ....
NP_006 GPFFSEV-VAYYEHIHQAVRLYNLPGVEGLSLDIS-SLVDIRDYVNKELALHIHTDIDSQ
840 850 860 870 880 890
750 760 770 780 790 800
pF1KB5 GRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQG
: :.:: :: .. :: :: :. .:.::. . :: :.. .::. : .. :
NP_006 GIFFTDLNGFQVQPRRY----LKKL----PLQANFYPMPVMAYIQDAQKRLTLHTAQALG
900 910 920 930 940
810 820 830 840 850 860
pF1KB5 GSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLA
:::.::.::... :::..::.::... : .: : : :. :. . . . .
NP_006 VSSLKDGQLEVILDRRLMQDDNRGLGQGLKDNKRTC-NRFRLLLERRTVGSEVQDSHSTS
950 960 970 980 990 1000
870 880 890 900 910
pF1KB5 EQEVLAPQVVL---APGGG---AAYNLGAPPRTQFSGLRRDLPPSVHLLTLAS-WGPEMV
.:. . . ::. . : ..: .: .: : .:: . :::.: . . : .
NP_006 YPSLLSHLTSMYLNAPALALPVARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDT
1010 1020 1030 1040 1050 1060
920 930 940 950 960
pF1KB5 LLRLEHQFAV---GEDSG---RNLSAPVTLN-----LRDLFSTFTITRLQETTLVANQLR
: : . . : : : .::. : . : .:: . .. :: :.:
NP_006 LPSAETALILHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPL
1070 1080 1090 1100 1110 1120
970 980 990 1000 1010
pF1KB5 EAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG
NP_006 ASPSNSTDVYLEPMEIATFRLRLG
1130 1140 1150
>>XP_016877674 (OMIM: 600988) PREDICTED: alpha-mannosida (1150 aa)
initn: 900 init1: 302 opt: 478 Z-score: 524.8 bits: 108.8 E(85289): 1.7e-22
Smith-Waterman score: 1058; 28.6% identity (55.9% similar) in 984 aa overlap (63-956:166-1120)
40 50 60 70 80 90
pF1KB5 PPLCFFLLLLAAAGARAGGYETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDI
:.: ..::.:.: ::.:: :.:. ..
XP_016 EELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGWIKTFDKYY---TEQT
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB5 QHAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFAN
:: ::.:..: : :: :::...:..::..:: . . . .:: :: .:.::.:.
XP_016 QH-----ILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGNGQLEIAT
200 210 220 230 240
160 170 180 190 200 210
pF1KB5 GGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMG
::::: ::: .:: :..::. : ..:: ..: . :: .: .::::.: . :. . .
XP_016 GGWVMPDEANSHYFALIDQLIEGHQWLERNLG--ATPRSGWAVDPFGYSSTMPYLLRRAN
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB5 FDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLP-NGYNPPRNLCWD-
. .... :. : : .: .:: . . . ..:.: ..: .:. :.. :
XP_016 LTSMLIQRVHYAIKKHFAATHSLEFMWRQTWD-SDSSTDIFCHMMPFYSYDVPHTCGPDP
310 320 330 340 350 360
280 290 300 310
pF1KB5 -VLC-----------VDQPLVEDPRS-PEYNAKELVDYFLNVATAQGRYYRTNHIVMTMG
. : .. : ::. : :. : . .:. ... .:.: ... .:
XP_016 KICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLLVPLG
370 380 390 400 410 420
320 330 340 350 360
pF1KB5 SDFQYENANMW---FKNLDKLIQLVNAQQAKGSSVHVLYSTPACYLWELNKANLT-----
.::.:.. . : : : ..:... :.. . :.. ..: . :. : : . .
XP_016 DDFRYDKPQEWDAQFFNYQRLFDFFNSR--PNLHVQAQFGTLSDYFDALYKRTGVEPGAR
430 440 450 460 470 480
370 380 390 400 410 420
pF1KB5 ---WSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVGLAAN--
. : ::: ::: ..::::..::: : .:. :. . : .:.. :
XP_016 PPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHARRS
490 500 510 520 530 540
430 440 450 460 470
pF1KB5 --VGPYGSGDSAPLNEA---MAVLQHHDAVSGTSRQHVANDYA-RQLAAGWGPCEVLLSN
.: : .: . :.:: ....:::::..::... :. ::. : : . . .:..
XP_016 GLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVIIHA
550 560 570 580 590 600
480 490 500 510 520
pF1KB5 ALARLRGFKDHFTFCQQ---LNISICPLSQTA------------ARFQVIVYNPLGRKVN
: . : :. . : . :... ::. : :: :...::: ..
XP_016 AHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRF-VVLFNPLEQERF
610 620 630 640 650 660
530 540 550 560 570 580
pF1KB5 WMVRLPVSEGVFVVKDPNGRTVPSDVVIFPSSDSQAHPPELLFSAS--LPALGFSTYSVA
:: : :. : . .:. . .. :: ..: : :. :::::... ..
XP_016 SMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQLQ
670 680 690 700 710 720
590 600 610 620
pF1KB5 -------QVP---RWKPQARA-----PQPIPRR---SWSPALTIENEHIRATFDPDTGLL
.: : ..: . .: : : . ... :..... :. ::::
XP_016 LGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLL
730 740 750 760 770 780
630 640 650 660 670 680
pF1KB5 MEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAYIFRPN-QQKPLPVSRWAQIHLVK
: .... : . . : : : . ::::.: :. . :: .. .....
XP_016 KSIRRVDEEHEQQVDMQVLVY----GTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTE
790 800 810 820 830
690 700 710 720 730 740
pF1KB5 TPLVQEVHQNFSAWCSQVVRLY--PGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETK
:. .:: . :.:::: :: . : :. : . . . : .::. .. : ....
XP_016 GPFFSEV-VAYYEHIHQAVRLYNLPGVEGLSLDIS-SLVDIRDYVNKELALHIHTDIDSQ
840 850 860 870 880 890
750 760 770 780 790 800
pF1KB5 GRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQG
: :.:: :: .. :: :: :. .:.::. . :: :.. .::. : .. :
XP_016 GIFFTDLNGFQVQPRRY----LKKL----PLQANFYPMPVMAYIQDAQKRLTLHTAQALG
900 910 920 930 940
810 820 830 840 850 860
pF1KB5 GSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLA
:::.::.::... :::..::.::... : .: : : :. :. . . . .
XP_016 VSSLKDGQLEVILDRRLMQDDNRGLGQGLKDNKRTC-NRFRLLLERRTVGSEVQDSHSTS
950 960 970 980 990 1000
870 880 890 900 910
pF1KB5 EQEVLAPQVVL---APGGG---AAYNLGAPPRTQFSGLRRDLPPSVHLLTLAS-WGPEMV
.:. . . ::. . : ..: .: .: : .:: . :::.: . . : .
XP_016 YPSLLSHLTSMYLNAPALALPVARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQAEEDT
1010 1020 1030 1040 1050 1060
920 930 940 950 960
pF1KB5 LLRLEHQFAV---GEDSG---RNLSAPVTLN-----LRDLFSTFTITRLQETTLVANQLR
: : . . : : : .::. : . : .:: . .. :: :.:
XP_016 LPSAETALILHRKGFDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPL
1070 1080 1090 1100 1110 1120
970 980 990 1000 1010
pF1KB5 EAASRLKWTTNTGPTPHQTPYQLDPANITLEPMEIRTFLASVQWKEVDG
XP_016 ASPSNSTDVYLEPMEIATFRLRLG
1130 1140 1150
>>XP_005254967 (OMIM: 600988) PREDICTED: alpha-mannosida (1175 aa)
initn: 839 init1: 302 opt: 478 Z-score: 524.7 bits: 108.9 E(85289): 1.7e-22
Smith-Waterman score: 1038; 29.3% identity (57.5% similar) in 842 aa overlap (63-832:166-979)
40 50 60 70 80 90
pF1KB5 PPLCFFLLLLAAAGARAGGYETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDI
:.: ..::.:.: ::.:: :.:. ..
XP_005 EELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGWIKTFDKYY---TEQT
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB5 QHAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFAN
:: ::.:..: : :: :::...:..::..:: . . . .:: :: .:.::.:.
XP_005 QH-----ILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGNGQLEIAT
200 210 220 230 240
160 170 180 190 200 210
pF1KB5 GGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMG
::::: ::: .:: :..::. : ..:: ..: . :: .: .::::.: . :. . .
XP_005 GGWVMPDEANSHYFALIDQLIEGHQWLERNLG--ATPRSGWAVDPFGYSSTMPYLLRRAN
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB5 FDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLP-NGYNPPRNLCWD-
. .... :. : : .: .:: . . . ..:.: ..: .:. :.. :
XP_005 LTSMLIQRVHYAIKKHFAATHSLEFMWRQTWD-SDSSTDIFCHMMPFYSYDVPHTCGPDP
310 320 330 340 350 360
280 290 300 310
pF1KB5 -VLC-----------VDQPLVEDPRS-PEYNAKELVDYFLNVATAQGRYYRTNHIVMTMG
. : .. : ::. : :. : . .:. ... .:.: ... .:
XP_005 KICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLLVPLG
370 380 390 400 410 420
320 330 340 350 360
pF1KB5 SDFQYENANMW---FKNLDKLIQLVNAQQAKGSSVHVLYSTPACYLWELNKANLT-----
.::.:.. . : : : ..:... :.. . :.. ..: . :. : : . .
XP_005 DDFRYDKPQEWDAQFFNYQRLFDFFNSR--PNLHVQAQFGTLSDYFDALYKRTGVEPGAR
430 440 450 460 470 480
370 380 390 400 410 420
pF1KB5 ---WSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVGLAAN--
. : ::: ::: ..::::..::: : .:. :. . : .:.. :
XP_005 PPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHARRS
490 500 510 520 530 540
430 440 450 460 470
pF1KB5 --VGPYGSGDSAPLNEA---MAVLQHHDAVSGTSRQHVANDYA-RQLAAGWGPCEVLLSN
.: : .: . :.:: ....:::::..::... :. ::. : : . . .:..
XP_005 GLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVIIHA
550 560 570 580 590 600
480 490 500 510 520
pF1KB5 ALARLRGFKDHFTFCQQ---LNISICPLSQTA------------ARFQVIVYNPLGRKVN
: . : :. . : . :... ::. : :: :...::: ..
XP_005 AHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRF-VVLFNPLEQERF
610 620 630 640 650 660
530 540 550 560 570 580
pF1KB5 WMVRLPVSEGVFVVKDPNGRTVPSDVVIFPSSDSQAHPPELLFSAS--LPALGFSTYSVA
:: : :. : . .:. . .. :: ..: : :. :::::... ..
XP_005 SMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQLQ
670 680 690 700 710 720
590 600 610 620
pF1KB5 -------QVP---RWKPQARA-----PQPIPRR---SWSPALTIENEHIRATFDPDTGLL
.: : ..: . .: : : . ... :..... :. ::::
XP_005 LGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLL
730 740 750 760 770 780
630 640 650 660 670 680
pF1KB5 MEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAYIFRPN-QQKPLPVSRWAQIHLVK
: .... : . . : : : . ::::.: :. . :: .. .....
XP_005 KSIRRVDEEHEQQVDMQVLVY----GTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTE
790 800 810 820 830
690 700 710 720 730 740
pF1KB5 TPLVQEVHQNFSAWCSQVVRLY--PGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETK
:. .:: . :.:::: :: . : :. : . . . : .::. .. : ....
XP_005 GPFFSEV-VAYYEHIHQAVRLYNLPGVEGLSLDIS-SLVDIRDYVNKELALHIHTDIDSQ
840 850 860 870 880 890
750 760 770 780 790 800
pF1KB5 GRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQG
: :.:: :: .. :: :: :. .:.::. . :: :.. .::. : .. :
XP_005 GIFFTDLNGFQVQPRRY----LKKL----PLQANFYPMPVMAYIQDAQKRLTLHTAQALG
900 910 920 930 940
810 820 830 840 850 860
pF1KB5 GSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLA
:::.::.::... :::..::.::... : .:
XP_005 VSSLKDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEPDFFSKLAA
950 960 970 980 990 1000
870 880 890 900 910 920
pF1KB5 EQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQ
XP_005 MFRGLIFHSSRSGNREVQDSHSTSYPSLLSHLTSMYLNAPALALPVARMQLPGPGLRSFH
1010 1020 1030 1040 1050 1060
>>XP_016877673 (OMIM: 600988) PREDICTED: alpha-mannosida (1175 aa)
initn: 839 init1: 302 opt: 478 Z-score: 524.7 bits: 108.9 E(85289): 1.7e-22
Smith-Waterman score: 1038; 29.3% identity (57.5% similar) in 842 aa overlap (63-832:166-979)
40 50 60 70 80 90
pF1KB5 PPLCFFLLLLAAAGARAGGYETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDI
:.: ..::.:.: ::.:: :.:. ..
XP_016 EELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGWIKTFDKYY---TEQT
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB5 QHAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFAN
:: ::.:..: : :: :::...:..::..:: . . . .:: :: .:.::.:.
XP_016 QH-----ILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGNGQLEIAT
200 210 220 230 240
160 170 180 190 200 210
pF1KB5 GGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMG
::::: ::: .:: :..::. : ..:: ..: . :: .: .::::.: . :. . .
XP_016 GGWVMPDEANSHYFALIDQLIEGHQWLERNLG--ATPRSGWAVDPFGYSSTMPYLLRRAN
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB5 FDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLP-NGYNPPRNLCWD-
. .... :. : : .: .:: . . . ..:.: ..: .:. :.. :
XP_016 LTSMLIQRVHYAIKKHFAATHSLEFMWRQTWD-SDSSTDIFCHMMPFYSYDVPHTCGPDP
310 320 330 340 350 360
280 290 300 310
pF1KB5 -VLC-----------VDQPLVEDPRS-PEYNAKELVDYFLNVATAQGRYYRTNHIVMTMG
. : .. : ::. : :. : . .:. ... .:.: ... .:
XP_016 KICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLLVPLG
370 380 390 400 410 420
320 330 340 350 360
pF1KB5 SDFQYENANMW---FKNLDKLIQLVNAQQAKGSSVHVLYSTPACYLWELNKANLT-----
.::.:.. . : : : ..:... :.. . :.. ..: . :. : : . .
XP_016 DDFRYDKPQEWDAQFFNYQRLFDFFNSR--PNLHVQAQFGTLSDYFDALYKRTGVEPGAR
430 440 450 460 470 480
370 380 390 400 410 420
pF1KB5 ---WSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVGLAAN--
. : ::: ::: ..::::..::: : .:. :. . : .:.. :
XP_016 PPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHARRS
490 500 510 520 530 540
430 440 450 460 470
pF1KB5 --VGPYGSGDSAPLNEA---MAVLQHHDAVSGTSRQHVANDYA-RQLAAGWGPCEVLLSN
.: : .: . :.:: ....:::::..::... :. ::. : : . . .:..
XP_016 GLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVIIHA
550 560 570 580 590 600
480 490 500 510 520
pF1KB5 ALARLRGFKDHFTFCQQ---LNISICPLSQTA------------ARFQVIVYNPLGRKVN
: . : :. . : . :... ::. : :: :...::: ..
XP_016 AHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRF-VVLFNPLEQERF
610 620 630 640 650 660
530 540 550 560 570 580
pF1KB5 WMVRLPVSEGVFVVKDPNGRTVPSDVVIFPSSDSQAHPPELLFSAS--LPALGFSTYSVA
:: : :. : . .:. . .. :: ..: : :. :::::... ..
XP_016 SMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQLQ
670 680 690 700 710 720
590 600 610 620
pF1KB5 -------QVP---RWKPQARA-----PQPIPRR---SWSPALTIENEHIRATFDPDTGLL
.: : ..: . .: : : . ... :..... :. ::::
XP_016 LGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLL
730 740 750 760 770 780
630 640 650 660 670 680
pF1KB5 MEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAYIFRPN-QQKPLPVSRWAQIHLVK
: .... : . . : : : . ::::.: :. . :: .. .....
XP_016 KSIRRVDEEHEQQVDMQVLVY----GTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTE
790 800 810 820 830
690 700 710 720 730 740
pF1KB5 TPLVQEVHQNFSAWCSQVVRLY--PGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETK
:. .:: . :.:::: :: . : :. : . . . : .::. .. : ....
XP_016 GPFFSEV-VAYYEHIHQAVRLYNLPGVEGLSLDIS-SLVDIRDYVNKELALHIHTDIDSQ
840 850 860 870 880 890
750 760 770 780 790 800
pF1KB5 GRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQG
: :.:: :: .. :: :: :. .:.::. . :: :.. .::. : .. :
XP_016 GIFFTDLNGFQVQPRRY----LKKL----PLQANFYPMPVMAYIQDAQKRLTLHTAQALG
900 910 920 930 940
810 820 830 840 850 860
pF1KB5 GSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLA
:::.::.::... :::..::.::... : .:
XP_016 VSSLKDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEPDFFSKLAA
950 960 970 980 990 1000
870 880 890 900 910 920
pF1KB5 EQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQ
XP_016 MFRGLIFHSSRSGNREVQDSHSTSYPSLLSHLTSMYLNAPALALPVARMQLPGPGLRSFH
1010 1020 1030 1040 1050 1060
>>NP_001307906 (OMIM: 600988) alpha-mannosidase 2x isofo (1175 aa)
initn: 839 init1: 302 opt: 478 Z-score: 524.7 bits: 108.9 E(85289): 1.7e-22
Smith-Waterman score: 1038; 29.3% identity (57.5% similar) in 842 aa overlap (63-832:166-979)
40 50 60 70 80 90
pF1KB5 PPLCFFLLLLAAAGARAGGYETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDI
:.: ..::.:.: ::.:: :.:. ..
NP_001 EELPFDNVDGGVWRQGFDISYDPHDWDAEDLQVFVVPHSHNDPGWIKTFDKYY---TEQT
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB5 QHAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFAN
:: ::.:..: : :: :::...:..::..:: . . . .:: :: .:.::.:.
NP_001 QH-----ILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGNGQLEIAT
200 210 220 230 240
160 170 180 190 200 210
pF1KB5 GGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMG
::::: ::: .:: :..::. : ..:: ..: . :: .: .::::.: . :. . .
NP_001 GGWVMPDEANSHYFALIDQLIEGHQWLERNLG--ATPRSGWAVDPFGYSSTMPYLLRRAN
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB5 FDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLP-NGYNPPRNLCWD-
. .... :. : : .: .:: . . . ..:.: ..: .:. :.. :
NP_001 LTSMLIQRVHYAIKKHFAATHSLEFMWRQTWD-SDSSTDIFCHMMPFYSYDVPHTCGPDP
310 320 330 340 350 360
280 290 300 310
pF1KB5 -VLC-----------VDQPLVEDPRS-PEYNAKELVDYFLNVATAQGRYYRTNHIVMTMG
. : .. : ::. : :. : . .:. ... .:.: ... .:
NP_001 KICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLLVPLG
370 380 390 400 410 420
320 330 340 350 360
pF1KB5 SDFQYENANMW---FKNLDKLIQLVNAQQAKGSSVHVLYSTPACYLWELNKANLT-----
.::.:.. . : : : ..:... :.. . :.. ..: . :. : : . .
NP_001 DDFRYDKPQEWDAQFFNYQRLFDFFNSR--PNLHVQAQFGTLSDYFDALYKRTGVEPGAR
430 440 450 460 470 480
370 380 390 400 410 420
pF1KB5 ---WSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVGLAAN--
. : ::: ::: ..::::..::: : .:. :. . : .:.. :
NP_001 PPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHARRS
490 500 510 520 530 540
430 440 450 460 470
pF1KB5 --VGPYGSGDSAPLNEA---MAVLQHHDAVSGTSRQHVANDYA-RQLAAGWGPCEVLLSN
.: : .: . :.:: ....:::::..::... :. ::. : : . . .:..
NP_001 GLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVIIHA
550 560 570 580 590 600
480 490 500 510 520
pF1KB5 ALARLRGFKDHFTFCQQ---LNISICPLSQTA------------ARFQVIVYNPLGRKVN
: . : :. . : . :... ::. : :: :...::: ..
NP_001 AHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALPERTVIQLDSSPRF-VVLFNPLEQERF
610 620 630 640 650 660
530 540 550 560 570 580
pF1KB5 WMVRLPVSEGVFVVKDPNGRTVPSDVVIFPSSDSQAHPPELLFSAS--LPALGFSTYSVA
:: : :. : . .:. . .. :: ..: : :. :::::... ..
NP_001 SMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVPDVYQVSVPVRLPALGLGVLQLQ
670 680 690 700 710 720
590 600 610 620
pF1KB5 -------QVP---RWKPQARA-----PQPIPRR---SWSPALTIENEHIRATFDPDTGLL
.: : ..: . .: : : . ... :..... :. ::::
NP_001 LGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLL
730 740 750 760 770 780
630 640 650 660 670 680
pF1KB5 MEIMNMNQQLLLPVRQTFFWYNASIGDNESDQASGAYIFRPN-QQKPLPVSRWAQIHLVK
: .... : . . : : : . ::::.: :. . :: .. .....
NP_001 KSIRRVDEEHEQQVDMQVLVY----GTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTE
790 800 810 820 830
690 700 710 720 730 740
pF1KB5 TPLVQEVHQNFSAWCSQVVRLY--PGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETK
:. .:: . :.:::: :: . : :. : . . . : .::. .. : ....
NP_001 GPFFSEV-VAYYEHIHQAVRLYNLPGVEGLSLDIS-SLVDIRDYVNKELALHIHTDIDSQ
840 850 860 870 880 890
750 760 770 780 790 800
pF1KB5 GRFYTDSNGREILERRRDYRPTWKLNQTEPVAGNYYPVNTRIYITDGNMQLTVLTDRSQG
: :.:: :: .. :: :: :. .:.::. . :: :.. .::. : .. :
NP_001 GIFFTDLNGFQVQPRRY----LKKL----PLQANFYPMPVMAYIQDAQKRLTLHTAQALG
900 910 920 930 940
810 820 830 840 850 860
pF1KB5 GSSLRDGSLELMVHRRLLKDDGRGVSEPLMENGSGAWVRGRHLVLLDTAQAAAAGHRLLA
:::.::.::... :::..::.::... : .:
NP_001 VSSLKDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSEPDFFSKLAA
950 960 970 980 990 1000
870 880 890 900 910 920
pF1KB5 EQEVLAPQVVLAPGGGAAYNLGAPPRTQFSGLRRDLPPSVHLLTLASWGPEMVLLRLEHQ
NP_001 MFRGLIFHSSRSGNREVQDSHSTSYPSLLSHLTSMYLNAPALALPVARMQLPGPGLRSFH
1010 1020 1030 1040 1050 1060
>>XP_011541697 (OMIM: 154582) PREDICTED: alpha-mannosida (884 aa)
initn: 563 init1: 271 opt: 458 Z-score: 504.2 bits: 104.6 E(85289): 2.4e-21
Smith-Waterman score: 806; 27.7% identity (58.0% similar) in 710 aa overlap (63-707:166-855)
40 50 60 70 80 90
pF1KB5 PPLCFFLLLLAAAGARAGGYETCPTVQPNMLNVHLLPHTHDDVGWLKTVDQYFYGIKNDI
:.: ..::.:.: ::::: ..::
XP_011 SLISFDNPDGGVWKQGFDITYESNEWDTEPLQVFVVPHSHNDPGWLKTFNDYFRD-----
140 150 160 170 180 190
100 110 120 130 140 150
pF1KB5 QHAGVQYILDSVISALLADPTRRFIYVEIAFFSRWWHQQTNATQEVVRDLVRQGRLEFAN
.:::..... : : :.::. ::...:.:: ...:..:...:.::...
XP_011 ---KTQYIFNNMVLKLKEDSRRKFIWSEISYLSKWWDIIDIQKKDAVKSLIENGQLEIVT
200 210 220 230 240
160 170 180 190 200 210
pF1KB5 GGWVMNDEAATHYGAIVDQMTLGLRFLEDTFGNDGRPRVAWHIDPFGHSREQASLFAQMG
::::: :::. :: :..::. : ..::...: .:: .: ::::::: .: :. . :
XP_011 GGWVMPDEATPHYFALIDQLIEGHQWLENNIGV--KPRSGWAIDPFGHSPTMAYLLNRAG
250 260 270 280 290 300
220 230 240 250 260 270
pF1KB5 FDGFFFGRLDYQDKWVRMQKLEMEQVWRASTSLKPPTADLFTGVLP-NGYNPPRNLCWDV
.. ... :. : : . .: :: . .: : :.. ..: .:. :.. :
XP_011 LSHMLIQRVHYAVKKHFALHKTLEFFWRQNWDLGSVT-DILCHMMPFYSYDIPHTCGPDP
310 320 330 340 350 360
280 290 300 310
pF1KB5 -LCVDQPLVEDPRS---------PEY----NAKELVDYFLNVATAQGRYYRTNHIVMTMG
.: . . . : . :: :.. . ..:. ... .::. .. .:
XP_011 KICCQFDFKRLPGGRFGCPWGVPPETIHPGNVQSRARMLLDQYRKKSKLFRTKVLLAPLG
370 380 390 400 410 420
320 330 340 350 360
pF1KB5 SDFQYENANMW---FKNLDKLIQLVNAQQAKGSSVHVLYSTPACYLWELNKANLT-----
.::.: . . : ::: ..:.. .:.:. .:.. ..: . .. :.::. :
XP_011 DDFRYCEYTEWDLQFKNYQQLFDYMNSQSK--FKVKIQFGTLSDFFDALDKADETQRDKG
430 440 450 460 470 480
370 380 390 400 410 420
pF1KB5 ---WSVKHDDFFPYADGPHQFWTGYFSSRPALKRYERLSYNFLQVCNQLEALVGLAAN--
. : ::: ::: ..:.:::.::: ::..:. . :.. . : .. :.
XP_011 QSMFPVLSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESHLRAAEILYYFALRQAHKY
490 500 510 520 530 540
430 440 450 460 470
pF1KB5 -VGPYGSGD-SAPLNEA---MAVLQHHDAVSGTSRQHVANDYARQLAAGWGPCEVLLSNA
.. . :.. . :.:: ....:::::..::... :. ::. .: . : ...:.
XP_011 KINKFLSSSLYTALTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFHSLMVLEKIIGNS
550 560 570 580 590 600
480 490 500 510 520
pF1KB5 LARLRGFKDHFTFCQQ-----LNISICPLSQ-----------TAARFQVIVYNPLGRKVN
: : .::..:. . :.... :: .: ..::::: .
XP_011 -AFLLILKDKLTYDSYSPDTFLEMDLKQKSQDSLPQKNIIRLSAEPRYLVVYNPLEQDRI
610 620 630 640 650 660
530 540 550 560 570 580
pF1KB5 WMVRLPVSEGVFVVKDPNGRTVPSDV-VIFPSSDSQAHPP-ELLFSASLPALGFSTYSV-
.: . :: . : . .:. : .: ... .... .. :. : : .: ::...:..
XP_011 SLVSVYVSSPTVQVFSASGKPVEVQVSAVWDTANTISETAYEISFRAHIPPLGLKVYKIL
670 680 690 700 710 720
590 600 610 620
pF1KB5 ---------AQVPRWKPQARAPQPIPRRSW---SPALTIENEHIRATFDPDTGLLMEIMN
:. .: ... . .. ..:.:: . :: .:::. ..:.
XP_011 ESASSNSHLADYVLYKNKVEDSGIFTIKNMINTEEGITLENSFVLLRFD-QTGLMKQMMT
730 740 750 760 770 780
630 640 650 660 670 680
pF1KB5 MNQQLLLPVRQTFFWYNASIGDNESDQASGAYIFRPN-QQKPLPVSRWAQIHLVKTPLVQ
.. : : ::...: . :. ::::.: :. . :: . ..... . .
XP_011 KEDGKHHEVNVQFSWYGTTI---KRDK-SGAYLFLPDGNAKPYVYTTPPFVRVTHGRIYS
790 800 810 820 830
690 700 710 720 730 740
pF1KB5 EVHQNFSAWCSQVVRLYPGQRHLELEWSVGPIPVGDTWGKEVISRFDTPLETKGRFYTDS
:: : .. :::: :
XP_011 EV-TCFFDHVTHRVRLYHIQGMKEKVILRDCKHILVTQIQNSEVIFGAV
840 850 860 870 880
1011 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 07:21:30 2016 done: Sat Nov 5 07:21:32 2016
Total Scan time: 14.210 Total Display time: 0.420
Function used was FASTA [36.3.4 Apr, 2011]