Result of FASTA (omim) for
pF1KB5659
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5659, 308 aa
1>>>pF1KB5659 308 - 308 aa - 308 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4168+/-0.000347; mu= 16.0609+/- 0.022
mean_var=94.8097+/-18.188, 0's: 0 Z-trim(116.3): 82 B-trim: 5 in 1/54
Lambda= 0.131719
statistics sampled from 27251 (27350) to 27251 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.695), E-opt: 0.2 (0.321), width: 16
Scan time: 7.130
The best scores are: opt bits E(85289)
NP_009016 (OMIM: 605547) follistatin-related prote ( 308) 2146 417.9 1.3e-116
XP_016864444 (OMIM: 136470) PREDICTED: follistatin ( 279) 249 57.3 4e-08
XP_005248460 (OMIM: 136470) PREDICTED: follistatin ( 316) 249 57.4 4.4e-08
NP_006341 (OMIM: 136470) follistatin isoform FST31 ( 317) 249 57.4 4.4e-08
XP_005248459 (OMIM: 136470) PREDICTED: follistatin ( 330) 249 57.4 4.5e-08
XP_016864443 (OMIM: 136470) PREDICTED: follistatin ( 337) 249 57.4 4.6e-08
XP_005248458 (OMIM: 136470) PREDICTED: follistatin ( 343) 249 57.4 4.7e-08
NP_037541 (OMIM: 136470) follistatin isoform FST34 ( 344) 249 57.4 4.7e-08
XP_011541401 (OMIM: 136470) PREDICTED: follistatin ( 352) 249 57.4 4.8e-08
XP_005248457 (OMIM: 136470) PREDICTED: follistatin ( 357) 249 57.4 4.8e-08
NP_001278906 (OMIM: 606041) SPARC-like protein 1 i ( 539) 198 47.9 5.3e-05
NP_001278905 (OMIM: 606041) SPARC-like protein 1 i ( 539) 198 47.9 5.3e-05
NP_004675 (OMIM: 606041) SPARC-like protein 1 isof ( 664) 198 48.0 6.2e-05
NP_001121782 (OMIM: 606041) SPARC-like protein 1 i ( 664) 198 48.0 6.2e-05
NP_001191282 (OMIM: 607989) testican-3 isoform 4 [ ( 316) 183 44.8 0.00026
NP_001191284 (OMIM: 607989) testican-3 isoform 6 [ ( 340) 183 44.9 0.00028
NP_001191283 (OMIM: 607989) testican-3 isoform 5 [ ( 344) 183 44.9 0.00028
NP_001191281 (OMIM: 607989) testican-3 isoform 3 [ ( 385) 183 44.9 0.0003
NP_001035249 (OMIM: 607989) testican-3 isoform 1 p ( 433) 183 45.0 0.00033
XP_016863747 (OMIM: 607989) PREDICTED: testican-3 ( 433) 183 45.0 0.00033
NP_058646 (OMIM: 607989) testican-3 isoform 2 prec ( 436) 183 45.0 0.00033
XP_011530320 (OMIM: 607989) PREDICTED: testican-3 ( 436) 183 45.0 0.00033
XP_016863746 (OMIM: 607989) PREDICTED: testican-3 ( 445) 183 45.0 0.00034
NP_003683 (OMIM: 603421) tomoregulin-1 precursor [ ( 380) 181 44.5 0.00039
NP_001292074 (OMIM: 605734) tomoregulin-2 isoform ( 175) 172 42.5 0.00073
XP_016859229 (OMIM: 605734) PREDICTED: tomoregulin ( 266) 172 42.7 0.00099
XP_016859228 (OMIM: 605734) PREDICTED: tomoregulin ( 337) 172 42.8 0.0012
NP_001292063 (OMIM: 605734) tomoregulin-2 isoform ( 346) 172 42.8 0.0012
XP_011509192 (OMIM: 605734) PREDICTED: tomoregulin ( 365) 172 42.8 0.0012
NP_057276 (OMIM: 605734) tomoregulin-2 isoform 1 p ( 374) 172 42.8 0.0013
NP_001191287 (OMIM: 607989) testican-3 isoform 9 p ( 313) 171 42.6 0.0013
NP_001191285 (OMIM: 607989) testican-3 isoform 7 p ( 393) 169 42.3 0.0019
NP_444514 (OMIM: 608021) WAP, Kazal, immunoglobuli ( 548) 169 42.4 0.0025
XP_011539731 (OMIM: 103320,615120) PREDICTED: agri (2004) 167 42.6 0.0081
NP_940978 (OMIM: 103320,615120) agrin isoform 2 pr (2045) 167 42.6 0.0082
XP_005244806 (OMIM: 103320,615120) PREDICTED: agri (2049) 167 42.6 0.0082
NP_001292204 (OMIM: 103320,615120) agrin isoform 1 (2068) 167 42.6 0.0083
NP_001317270 (OMIM: 610895) WAP, Kazal, immunoglob ( 483) 159 40.5 0.0084
NP_783165 (OMIM: 610895) WAP, Kazal, immunoglobuli ( 576) 159 40.5 0.0095
>>NP_009016 (OMIM: 605547) follistatin-related protein 1 (308 aa)
initn: 2146 init1: 2146 opt: 2146 Z-score: 2214.5 bits: 417.9 E(85289): 1.3e-116
Smith-Waterman score: 2146; 100.0% identity (100.0% similar) in 308 aa overlap (1-308:1-308)
10 20 30 40 50 60
pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCKP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKEKKSVSPSASPVVCYQSNRDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAIN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNETAIN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ITTYPDQENNKLLRGLCVDALIELSDENADWKLSFQEFLKCLNPSFNPPEKKCALEDETY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 ADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQETAEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ADGAETEVDCNRCVCACGNWVCTAMTCDGKNQKGAQTQTEEEMTRYVQELQKHQETAEKT
250 260 270 280 290 300
pF1KB5 KRVSTKEI
::::::::
NP_009 KRVSTKEI
>>XP_016864444 (OMIM: 136470) PREDICTED: follistatin iso (279 aa)
initn: 395 init1: 131 opt: 249 Z-score: 266.8 bits: 57.3 E(85289): 4e-08
Smith-Waterman score: 249; 38.5% identity (64.8% similar) in 91 aa overlap (31-117:17-107)
10 20 30 40 50
pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCK-
: :: :: :..: ...:..: :.: .:.
XP_016 MIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSN
10 20 30 40
60 70 80 90 100 110
pF1KB5 -PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKE--KKSVSPSASPVVCYQS
: :::: .:::: :.: : . : ...:.:.:.::. . :..: : :.
XP_016 ITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQT
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB5 NRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNE
:
XP_016 NNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCISRYS
110 120 130 140 150 160
>>XP_005248460 (OMIM: 136470) PREDICTED: follistatin iso (316 aa)
initn: 395 init1: 131 opt: 249 Z-score: 266.1 bits: 57.4 E(85289): 4.4e-08
Smith-Waterman score: 249; 38.5% identity (64.8% similar) in 91 aa overlap (31-117:95-185)
10 20 30 40 50
pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCK-
: :: :: :..: ...:..: :.: .:.
XP_005 WTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSN
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB5 -PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKE--KKSVSPSASPVVCYQS
: :::: .:::: :.: : . : ...:.:.:.::. . :..: : :.
XP_005 ITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQT
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB5 NRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNE
:
XP_005 NNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCITKSC
190 200 210 220 230 240
>>NP_006341 (OMIM: 136470) follistatin isoform FST317 pr (317 aa)
initn: 247 init1: 131 opt: 249 Z-score: 266.1 bits: 57.4 E(85289): 4.4e-08
Smith-Waterman score: 249; 38.5% identity (64.8% similar) in 91 aa overlap (31-117:95-185)
10 20 30 40 50
pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCK-
: :: :: :..: ...:..: :.: .:.
NP_006 WTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSN
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB5 -PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKE--KKSVSPSASPVVCYQS
: :::: .:::: :.: : . : ...:.:.:.::. . :..: : :.
NP_006 ITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQT
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB5 NRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNE
:
NP_006 NNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKS
190 200 210 220 230 240
>>XP_005248459 (OMIM: 136470) PREDICTED: follistatin iso (330 aa)
initn: 395 init1: 131 opt: 249 Z-score: 265.8 bits: 57.4 E(85289): 4.5e-08
Smith-Waterman score: 249; 38.5% identity (64.8% similar) in 91 aa overlap (31-117:95-185)
10 20 30 40 50
pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCK-
: :: :: :..: ...:..: :.: .:.
XP_005 WTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSN
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB5 -PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKE--KKSVSPSASPVVCYQS
: :::: .:::: :.: : . : ...:.:.:.::. . :..: : :.
XP_005 ITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQT
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB5 NRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNE
:
XP_005 NNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCISRYS
190 200 210 220 230 240
>>XP_016864443 (OMIM: 136470) PREDICTED: follistatin iso (337 aa)
initn: 395 init1: 131 opt: 249 Z-score: 265.7 bits: 57.4 E(85289): 4.6e-08
Smith-Waterman score: 249; 38.5% identity (64.8% similar) in 91 aa overlap (31-117:95-185)
10 20 30 40 50
pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCK-
: :: :: :..: ...:..: :.: .:.
XP_016 WTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSN
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB5 -PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKE--KKSVSPSASPVVCYQS
: :::: .:::: :.: : . : ...:.:.:.::. . :..: : :.
XP_016 ITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQT
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB5 NRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNE
:
XP_016 NNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCISRYS
190 200 210 220 230 240
>>XP_005248458 (OMIM: 136470) PREDICTED: follistatin iso (343 aa)
initn: 395 init1: 131 opt: 249 Z-score: 265.6 bits: 57.4 E(85289): 4.7e-08
Smith-Waterman score: 249; 38.5% identity (64.8% similar) in 91 aa overlap (31-117:95-185)
10 20 30 40 50
pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCK-
: :: :: :..: ...:..: :.: .:.
XP_005 WTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSN
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB5 -PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKE--KKSVSPSASPVVCYQS
: :::: .:::: :.: : . : ...:.:.:.::. . :..: : :.
XP_005 ITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQT
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB5 NRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNE
:
XP_005 NNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCITKSC
190 200 210 220 230 240
>>NP_037541 (OMIM: 136470) follistatin isoform FST344 pr (344 aa)
initn: 247 init1: 131 opt: 249 Z-score: 265.6 bits: 57.4 E(85289): 4.7e-08
Smith-Waterman score: 249; 38.5% identity (64.8% similar) in 91 aa overlap (31-117:95-185)
10 20 30 40 50
pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCK-
: :: :: :..: ...:..: :.: .:.
NP_037 WTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSN
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB5 -PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKE--KKSVSPSASPVVCYQS
: :::: .:::: :.: : . : ...:.:.:.::. . :..: : :.
NP_037 ITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQT
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB5 NRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNE
:
NP_037 NNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCIKAKS
190 200 210 220 230 240
>>XP_011541401 (OMIM: 136470) PREDICTED: follistatin iso (352 aa)
initn: 395 init1: 131 opt: 249 Z-score: 265.5 bits: 57.4 E(85289): 4.8e-08
Smith-Waterman score: 249; 38.5% identity (64.8% similar) in 91 aa overlap (31-117:90-180)
10 20 30 40 50
pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCK-
: :: :: :..: ...:..: :.: .:.
XP_011 WTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSN
60 70 80 90 100 110
60 70 80 90 100 110
pF1KB5 -PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKE--KKSVSPSASPVVCYQS
: :::: .:::: :.: : . : ...:.:.:.::. . :..: : :.
XP_011 ITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQT
120 130 140 150 160 170
120 130 140 150 160 170
pF1KB5 NRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNE
:
XP_011 NNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCISRYS
180 190 200 210 220 230
>>XP_005248457 (OMIM: 136470) PREDICTED: follistatin iso (357 aa)
initn: 395 init1: 131 opt: 249 Z-score: 265.4 bits: 57.4 E(85289): 4.8e-08
Smith-Waterman score: 249; 38.5% identity (64.8% similar) in 91 aa overlap (31-117:95-185)
10 20 30 40 50
pF1KB5 MWKRWLALALALVAVAWVRAEEELRSKSKICANVFCGAGRECAVTEKGEPTCLCIEQCK-
: :: :: :..: ...:..: :.: .:.
XP_005 WTEEDVNDNTLFKWMIFNGGAPNCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSN
70 80 90 100 110 120
60 70 80 90 100 110
pF1KB5 -PHKRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKE--KKSVSPSASPVVCYQS
: :::: .:::: :.: : . : ...:.:.:.::. . :..: : :.
XP_005 ITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQT
130 140 150 160 170 180
120 130 140 150 160 170
pF1KB5 NRDELRRRIIQWLEAEIIPDGWFSKGSNYSEILDKYFKNFDNGDSRLDSSEFLKFVEQNE
:
XP_005 NNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKCISRYS
190 200 210 220 230 240
308 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 13:11:02 2016 done: Sat Nov 5 13:11:03 2016
Total Scan time: 7.130 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]