Result of FASTA (omim) for
pF1KB5633
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5633, 522 aa
1>>>pF1KB5633 522 - 522 aa - 522 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6319+/-0.000454; mu= 14.3498+/- 0.028
mean_var=205.3279+/-45.036, 0's: 0 Z-trim(115.0): 140 B-trim: 0 in 0/54
Lambda= 0.089506
statistics sampled from 24975 (25132) to 24975 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.649), E-opt: 0.2 (0.295), width: 16
Scan time: 9.320
The best scores are: opt bits E(85289)
NP_004611 (OMIM: 602355) TNF receptor-associated f ( 522) 3654 485.3 1.9e-136
NP_665802 (OMIM: 602355) TNF receptor-associated f ( 522) 3654 485.3 1.9e-136
XP_016873709 (OMIM: 602355) PREDICTED: TNF recepto ( 324) 1444 199.6 1.2e-50
NP_004286 (OMIM: 602464) TNF receptor-associated f ( 470) 641 96.1 2.4e-19
XP_011535420 (OMIM: 601896,614849) PREDICTED: TNF ( 485) 625 94.1 1e-18
NP_001186356 (OMIM: 601896,614849) TNF receptor-as ( 485) 625 94.1 1e-18
NP_663777 (OMIM: 601896,614849) TNF receptor-assoc ( 568) 504 78.6 5.6e-14
XP_016877107 (OMIM: 601896,614849) PREDICTED: TNF ( 568) 504 78.6 5.6e-14
XP_016877106 (OMIM: 601896,614849) PREDICTED: TNF ( 568) 504 78.6 5.6e-14
NP_003291 (OMIM: 601896,614849) TNF receptor-assoc ( 568) 504 78.6 5.6e-14
NP_001029082 (OMIM: 602356) TNF receptor-associate ( 557) 498 77.8 9.5e-14
XP_016857710 (OMIM: 602356) PREDICTED: TNF recepto ( 557) 498 77.8 9.5e-14
NP_665702 (OMIM: 602356) TNF receptor-associated f ( 557) 498 77.8 9.5e-14
NP_004610 (OMIM: 602356) TNF receptor-associated f ( 557) 498 77.8 9.5e-14
XP_016877109 (OMIM: 601896,614849) PREDICTED: TNF ( 292) 486 75.9 1.9e-13
NP_663778 (OMIM: 601896,614849) TNF receptor-assoc ( 543) 411 66.5 2.3e-10
XP_016877108 (OMIM: 601896,614849) PREDICTED: TNF ( 543) 411 66.5 2.3e-10
XP_011535419 (OMIM: 601896,614849) PREDICTED: TNF ( 512) 401 65.2 5.3e-10
XP_016870584 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 399 64.9 6.3e-10
XP_011517280 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 399 64.9 6.3e-10
XP_011517279 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 399 64.9 6.3e-10
XP_011517277 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 399 64.9 6.3e-10
XP_011517276 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 399 64.9 6.3e-10
XP_011517278 (OMIM: 601895) PREDICTED: TNF recepto ( 501) 399 64.9 6.3e-10
NP_066961 (OMIM: 601895) TNF receptor-associated f ( 501) 399 64.9 6.3e-10
XP_016870583 (OMIM: 601895) PREDICTED: TNF recepto ( 533) 399 65.0 6.5e-10
XP_011517275 (OMIM: 601895) PREDICTED: TNF recepto ( 556) 399 65.0 6.7e-10
NP_001177876 (OMIM: 601711) TNF receptor-associate ( 294) 373 61.3 4.7e-09
NP_005649 (OMIM: 601711) TNF receptor-associated f ( 416) 373 61.5 5.8e-09
NP_001177874 (OMIM: 601711) TNF receptor-associate ( 416) 373 61.5 5.8e-09
XP_011535418 (OMIM: 601896,614849) PREDICTED: TNF ( 516) 366 60.7 1.2e-08
XP_011508261 (OMIM: 602356) PREDICTED: TNF recepto ( 568) 290 50.9 1.2e-05
NP_001306136 (OMIM: 602356) TNF receptor-associate ( 568) 290 50.9 1.2e-05
XP_011508262 (OMIM: 602356) PREDICTED: TNF recepto ( 568) 290 50.9 1.2e-05
XP_011508259 (OMIM: 602356) PREDICTED: TNF recepto ( 631) 284 50.2 2.1e-05
XP_011523808 (OMIM: 602464) PREDICTED: TNF recepto ( 454) 274 48.7 4.3e-05
XP_011523807 (OMIM: 602464) PREDICTED: TNF recepto ( 461) 274 48.7 4.3e-05
XP_011523806 (OMIM: 602464) PREDICTED: TNF recepto ( 477) 274 48.8 4.4e-05
XP_011523810 (OMIM: 602464) PREDICTED: TNF recepto ( 352) 268 47.8 6.3e-05
XP_011523809 (OMIM: 602464) PREDICTED: TNF recepto ( 352) 268 47.8 6.3e-05
XP_016861431 (OMIM: 609729) PREDICTED: E3 ubiquiti (1037) 253 46.5 0.00046
NP_055824 (OMIM: 609729) E3 ubiquitin-protein liga (1066) 253 46.5 0.00047
NP_001158067 (OMIM: 609730) PDZ domain-containing (1036) 220 42.2 0.0088
>>NP_004611 (OMIM: 602355) TNF receptor-associated facto (522 aa)
initn: 3654 init1: 3654 opt: 3654 Z-score: 2570.6 bits: 485.3 E(85289): 1.9e-136
Smith-Waterman score: 3654; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KB5 MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 QLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 HLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLE
430 440 450 460 470 480
490 500 510 520
pF1KB5 ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
::::::::::::::::::::::::::::::::::::::::::
NP_004 ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
490 500 510 520
>>NP_665802 (OMIM: 602355) TNF receptor-associated facto (522 aa)
initn: 3654 init1: 3654 opt: 3654 Z-score: 2570.6 bits: 485.3 E(85289): 1.9e-136
Smith-Waterman score: 3654; 100.0% identity (100.0% similar) in 522 aa overlap (1-522:1-522)
10 20 30 40 50 60
pF1KB5 MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 QLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 QLEGRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 GMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 GMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDS
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 HLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_665 HLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLE
430 440 450 460 470 480
490 500 510 520
pF1KB5 ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
::::::::::::::::::::::::::::::::::::::::::
NP_665 ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
490 500 510 520
>>XP_016873709 (OMIM: 602355) PREDICTED: TNF receptor-as (324 aa)
initn: 1444 init1: 1444 opt: 1444 Z-score: 1030.5 bits: 199.6 E(85289): 1.2e-50
Smith-Waterman score: 1449; 84.7% identity (88.0% similar) in 249 aa overlap (1-249:1-232)
10 20 30 40 50 60
pF1KB5 MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSLLNCENSCGSSQSESDCCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NFAKREILSLMVKCPNEGCLHKMELRHLEDHQAHCEFALMDCPQCQRPFQKFHINIHILK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 DCPRRQVSCDNCAASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPI
:::::::::::::::::::::: . :. . . .::. : :
XP_016 DCPRRQVSCDNCAASMAFEDKE----------------SFTLVAQAGVQWHDLSSPQ-PQ
190 200 210 220
250 260 270 280 290 300
pF1KB5 PCTFSTFGCHEKMQRNHLARHLQENTQSHMRMLAQAVHSLSVIPDSGYISEVRNFQETIH
: :. :.:
XP_016 PPGFKRFSCLSLLSSWDYRHVPPCPANIFVFLVETRFLHVGQAGLELPTSGNPPALASQS
230 240 250 260 270 280
>>NP_004286 (OMIM: 602464) TNF receptor-associated facto (470 aa)
initn: 749 init1: 143 opt: 641 Z-score: 468.4 bits: 96.1 E(85289): 2.4e-19
Smith-Waterman score: 746; 26.7% identity (57.8% similar) in 469 aa overlap (53-499:1-462)
30 40 50 60 70 80
pF1KB5 MASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALREAVQ
. :.: .: . . ::.: .:: ::
NP_004 MPGFDYKFLEKPKRRLLCPLCGKPMREPVQ
10 20 30
90 100 110 120 130
pF1KB5 -TPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKC--PNEGC
. :::::: .:. . . .. ::: :. : ...:: . ..:.: ..: .:::
NP_004 VSTCGHRFCDTCLQEFLSEGVFKCPEDQLPLDYAKIYPDPELEVQVLGLPIRCIHSEEGC
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 LHKMELRHLEDHQAHCEFALMDCP-QCQRPFQKFHINIHILKDCPRRQVSCDNCAASMAF
. ::::. : : : .. :: .: ... . :. .:::.:...:. :. ...
NP_004 RWSGPLRHLQGHLNTCSFNVIPCPNRCPMKLSRRDLPAHLQHDCPKRRLKCEFCGCDFSG
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB5 EDKEIHDQNCPLANVICEY-CNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEKMQRNH
: : :. :: .: :: :.. ..:. . .: .:: :::. : ... .
NP_004 EAYESHEGMCPQESVYCENKCGARMMRRLLAQHATSECPKRTQPCTY----CTKEFVFDT
160 170 180 190 200
260 270 280 290 300
pF1KB5 LARHLQENTQSHMRMLAQ-AVHSLSVIPDSGYISEVRN-------FQET--IHQLEGRLV
. : . . . : .: ... :.... : :... :. .:.
NP_004 IQSHQYQCPRLPVACPNQCGVGTVAREDLPGHLKDSCNTALVLCPFKDSGCKHRCP-KLA
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB5 RQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIEAQQCNGIYIWKIGNFGMHLKCQ
: . . .. . ::. .. .. :. .. :. . . .:. :::::..: .:.
NP_004 MARHVEESVKPHLAMMCALVSRQRQELQELRRELEELSVGS-DGVLIWKIGSYGRRLQEA
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB5 EEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSHLPWPFQ
. . . ::.::: : :::: . :. ... ....::..... : .:. : :::
NP_004 KAKPNLECFSPAFYTHKYGYKLQVSAFLN-GNGSGEGTHLSLYIRVLPGAFDNLLEWPFA
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB5 GTIRLTILDQSEAPVR--QNHEEIMDAKPELLAFQRP-----TIPRNPKGFGYVTFMHLE
. ...::::. . :. : . :. ::.: .. .. :::: :. .
NP_004 RRVTFSLLDQSDPGLAKPQHVTETFHPDPNWKNFQKPGTWRGSLDESSLGFGYPKFISHQ
390 400 410 420 430 440
490 500 510 520
pF1KB5 ALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
.:.:....::....: :
NP_004 DIRKRNYVRDDAVFIRAAVELPRKILS
450 460 470
>>XP_011535420 (OMIM: 601896,614849) PREDICTED: TNF rece (485 aa)
initn: 506 init1: 242 opt: 625 Z-score: 457.1 bits: 94.1 E(85289): 1e-18
Smith-Waterman score: 645; 28.7% identity (58.7% similar) in 470 aa overlap (49-501:32-479)
20 30 40 50 60 70
pF1KB5 CCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALR
:. : :: .: .:.::.: : ..:
XP_011 ESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLC
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB5 EAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNE-
:: ::::::..:. . ... :: . .: ......: :: :::::.:.. : ::
XP_011 SPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNES
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB5 -GCLHKMELRHLEDH-QAHCEFALMDC--PQCQRPFQKFHINIHILKDCPRRQVSCDNCA
:: ... : :: : . :.: . : :.:.. . . :. : : :...:..:
XP_011 RGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCK
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB5 ASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEK-
... . : : : : : ..: ... :. :.: ..:
XP_011 SQVPM----IALQVSLLQNESVEKNKSI---QSLHNQI----------CSFEIEIERQKE
190 200 210 220
260 270 280 290 300
pF1KB5 MQRNHLAR--HLQENTQSH---MRMLAQAVHSLSVIPD--SGYISEVRNFQETIHQLEGR
: ::. .. :::. .:. .. : . .. . . ... : :...:. . .::.
XP_011 MLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELES-
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 LVRQDHQIRELTAKMETQ-SMYVSELK-RTIRT--LEDKVAEIEAQQCNGIYIWKIGNFG
. .. :. . :. .:.: : . . :. . :: .. . .:. . ::. :::: ..
XP_011 VDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYK
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 MHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSH
. . : . ..: :::: :::.: :..:. . ....::: :.::::.
XP_011 RRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGK-GTHLSLFFVIMRGEYDAL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB5 LPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEA
:::::. . : ..::. . :.. . . :. .:..:: : . : .:. .
XP_011 LPWPFKQKVTLMLMDQGSS--RRHLGDAFKPDPNSSSFKKPTGEMNIAS-GCPVFVAQTV
410 420 430 440 450
490 500 510 520
pF1KB5 LRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
:.. :.:::::.... :.:
XP_011 LENGTYIKDDTIFIKVIVDTSDLPDP
460 470 480
>>NP_001186356 (OMIM: 601896,614849) TNF receptor-associ (485 aa)
initn: 506 init1: 242 opt: 625 Z-score: 457.1 bits: 94.1 E(85289): 1e-18
Smith-Waterman score: 645; 28.7% identity (58.7% similar) in 470 aa overlap (49-501:32-479)
20 30 40 50 60 70
pF1KB5 CCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALR
:. : :: .: .:.::.: : ..:
NP_001 ESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLC
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB5 EAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNE-
:: ::::::..:. . ... :: . .: ......: :: :::::.:.. : ::
NP_001 SPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNES
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB5 -GCLHKMELRHLEDH-QAHCEFALMDC--PQCQRPFQKFHINIHILKDCPRRQVSCDNCA
:: ... : :: : . :.: . : :.:.. . . :. : : :...:..:
NP_001 RGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCK
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB5 ASMAFEDKEIHDQNCPLANVICEYCNTILIREQMPNHYDLDCPTAPIPCTFSTFGCHEK-
... . : : : : : ..: ... :. :.: ..:
NP_001 SQVPM----IALQVSLLQNESVEKNKSI---QSLHNQI----------CSFEIEIERQKE
190 200 210 220
260 270 280 290 300
pF1KB5 MQRNHLAR--HLQENTQSH---MRMLAQAVHSLSVIPD--SGYISEVRNFQETIHQLEGR
: ::. .. :::. .:. .. : . .. . . ... : :...:. . .::.
NP_001 MLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNRVTELES-
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB5 LVRQDHQIRELTAKMETQ-SMYVSELK-RTIRT--LEDKVAEIEAQQCNGIYIWKIGNFG
. .. :. . :. .:.: : . . :. . :: .. . .:. . ::. :::: ..
NP_001 VDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYK
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB5 MHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQGEYDSH
. . : . ..: :::: :::.: :..:. . ....::: :.::::.
NP_001 RRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGK-GTHLSLFFVIMRGEYDAL
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB5 LPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVTFMHLEA
:::::. . : ..::. . :.. . . :. .:..:: : . : .:. .
NP_001 LPWPFKQKVTLMLMDQGSS--RRHLGDAFKPDPNSSSFKKPTGEMNIAS-GCPVFVAQTV
410 420 430 440 450
490 500 510 520
pF1KB5 LRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
:.. :.:::::.... :.:
NP_001 LENGTYIKDDTIFIKVIVDTSDLPDP
460 470 480
>>NP_663777 (OMIM: 601896,614849) TNF receptor-associate (568 aa)
initn: 506 init1: 242 opt: 504 Z-score: 371.9 bits: 78.6 E(85289): 5.6e-14
Smith-Waterman score: 638; 26.3% identity (54.2% similar) in 498 aa overlap (49-463:32-525)
20 30 40 50 60 70
pF1KB5 CCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALR
:. : :: .: .:.::.: : ..:
NP_663 ESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLC
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB5 EAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNE-
:: ::::::..:. . ... :: . .: ......: :: :::::.:.. : ::
NP_663 SPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNES
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB5 -GCLHKMELRHLEDH-QAHCEFALMDC--PQCQRPFQKFHINIHILKDCPRRQVSCDNCA
:: ... : :: : . :.: . : :.:.. . . :. : : :...:..:
NP_663 RGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCK
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB5 ASMAFEDKEIH-DQNCPLANVICEY-CNT-ILIREQMPNHYDLDCPTAPIPCTFSTFGCH
... . . : : .:: . : : . :.. :.: .. : . .: .:: :.:. .::
NP_663 SQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLS-ECVNAPSTCSFKRYGCV
190 200 210 220 230 240
260 270 280 290 300
pF1KB5 EKMQRNHLARHLQENTQSHMRMLAQAVHSL----SVIPDSGYISE--VRNFQETIHQLEG
. ... : .. .:. .: . .:: :.. . . .. ...... : ..:
NP_663 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
250 260 270 280 290 300
310 320 330 340
pF1KB5 RLVRQDHQIRELTAKM-------ETQSMYVSELKRTIR-----------------TLEDK
.. :: ...:. .:. ..:. ..:: . :: .:...
NP_663 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
310 320 330 340 350 360
350
pF1KB5 VAEIE-----AQQC----------------------------------------NGIYIW
:.:.: : : ::. ::
NP_663 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
370 380 390 400 410 420
360 370 380 390 400 410
pF1KB5 KIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQ
:: .. . . : . ..: :::: :::.: :..:. . ....::: :.
NP_663 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGK-GTHLSLFFVIMR
430 440 450 460 470
420 430 440 450 460 470
pF1KB5 GEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVT
::::. :::::. . : ..::. . :.. . . :. .:..::
NP_663 GEYDALLPWPFKQKVTLMLMDQGSS--RRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVF
480 490 500 510 520 530
480 490 500 510 520
pF1KB5 FMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
NP_663 VAQTVLENGTYIKDDTIFIKVIVDTSDLPDP
540 550 560
>>XP_016877107 (OMIM: 601896,614849) PREDICTED: TNF rece (568 aa)
initn: 506 init1: 242 opt: 504 Z-score: 371.9 bits: 78.6 E(85289): 5.6e-14
Smith-Waterman score: 638; 26.3% identity (54.2% similar) in 498 aa overlap (49-463:32-525)
20 30 40 50 60 70
pF1KB5 CCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALR
:. : :: .: .:.::.: : ..:
XP_016 ESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLC
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB5 EAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNE-
:: ::::::..:. . ... :: . .: ......: :: :::::.:.. : ::
XP_016 SPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNES
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB5 -GCLHKMELRHLEDH-QAHCEFALMDC--PQCQRPFQKFHINIHILKDCPRRQVSCDNCA
:: ... : :: : . :.: . : :.:.. . . :. : : :...:..:
XP_016 RGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCK
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB5 ASMAFEDKEIH-DQNCPLANVICEY-CNT-ILIREQMPNHYDLDCPTAPIPCTFSTFGCH
... . . : : .:: . : : . :.. :.: .. : . .: .:: :.:. .::
XP_016 SQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLS-ECVNAPSTCSFKRYGCV
190 200 210 220 230 240
260 270 280 290 300
pF1KB5 EKMQRNHLARHLQENTQSHMRMLAQAVHSL----SVIPDSGYISE--VRNFQETIHQLEG
. ... : .. .:. .: . .:: :.. . . .. ...... : ..:
XP_016 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
250 260 270 280 290 300
310 320 330 340
pF1KB5 RLVRQDHQIRELTAKM-------ETQSMYVSELKRTIR-----------------TLEDK
.. :: ...:. .:. ..:. ..:: . :: .:...
XP_016 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
310 320 330 340 350 360
350
pF1KB5 VAEIE-----AQQC----------------------------------------NGIYIW
:.:.: : : ::. ::
XP_016 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
370 380 390 400 410 420
360 370 380 390 400 410
pF1KB5 KIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQ
:: .. . . : . ..: :::: :::.: :..:. . ....::: :.
XP_016 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGK-GTHLSLFFVIMR
430 440 450 460 470
420 430 440 450 460 470
pF1KB5 GEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVT
::::. :::::. . : ..::. . :.. . . :. .:..::
XP_016 GEYDALLPWPFKQKVTLMLMDQGSS--RRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVF
480 490 500 510 520 530
480 490 500 510 520
pF1KB5 FMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
XP_016 VAQTVLENGTYIKDDTIFIKVIVDTSDLPDP
540 550 560
>>XP_016877106 (OMIM: 601896,614849) PREDICTED: TNF rece (568 aa)
initn: 506 init1: 242 opt: 504 Z-score: 371.9 bits: 78.6 E(85289): 5.6e-14
Smith-Waterman score: 638; 26.3% identity (54.2% similar) in 498 aa overlap (49-463:32-525)
20 30 40 50 60 70
pF1KB5 CCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALR
:. : :: .: .:.::.: : ..:
XP_016 ESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLC
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB5 EAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNE-
:: ::::::..:. . ... :: . .: ......: :: :::::.:.. : ::
XP_016 SPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNES
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB5 -GCLHKMELRHLEDH-QAHCEFALMDC--PQCQRPFQKFHINIHILKDCPRRQVSCDNCA
:: ... : :: : . :.: . : :.:.. . . :. : : :...:..:
XP_016 RGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCK
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB5 ASMAFEDKEIH-DQNCPLANVICEY-CNT-ILIREQMPNHYDLDCPTAPIPCTFSTFGCH
... . . : : .:: . : : . :.. :.: .. : . .: .:: :.:. .::
XP_016 SQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLS-ECVNAPSTCSFKRYGCV
190 200 210 220 230 240
260 270 280 290 300
pF1KB5 EKMQRNHLARHLQENTQSHMRMLAQAVHSL----SVIPDSGYISE--VRNFQETIHQLEG
. ... : .. .:. .: . .:: :.. . . .. ...... : ..:
XP_016 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
250 260 270 280 290 300
310 320 330 340
pF1KB5 RLVRQDHQIRELTAKM-------ETQSMYVSELKRTIR-----------------TLEDK
.. :: ...:. .:. ..:. ..:: . :: .:...
XP_016 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
310 320 330 340 350 360
350
pF1KB5 VAEIE-----AQQC----------------------------------------NGIYIW
:.:.: : : ::. ::
XP_016 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
370 380 390 400 410 420
360 370 380 390 400 410
pF1KB5 KIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQ
:: .. . . : . ..: :::: :::.: :..:. . ....::: :.
XP_016 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGK-GTHLSLFFVIMR
430 440 450 460 470
420 430 440 450 460 470
pF1KB5 GEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVT
::::. :::::. . : ..::. . :.. . . :. .:..::
XP_016 GEYDALLPWPFKQKVTLMLMDQGSS--RRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVF
480 490 500 510 520 530
480 490 500 510 520
pF1KB5 FMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
XP_016 VAQTVLENGTYIKDDTIFIKVIVDTSDLPDP
540 550 560
>>NP_003291 (OMIM: 601896,614849) TNF receptor-associate (568 aa)
initn: 506 init1: 242 opt: 504 Z-score: 371.9 bits: 78.6 E(85289): 5.6e-14
Smith-Waterman score: 638; 26.3% identity (54.2% similar) in 498 aa overlap (49-463:32-525)
20 30 40 50 60 70
pF1KB5 CCVAMASSCSAVTKDDSVGGTASTGNLSSSFMEEIQGYDVEFDPPLESKYECPICLMALR
:. : :: .: .:.::.: : ..:
NP_003 ESSKKMDSPGALQTNPPLKLHTDRSAGTPVFVPEQGGYKEKFVKTVEDKYKCEKCHLVLC
10 20 30 40 50 60
80 90 100 110 120 130
pF1KB5 EAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPDNFAKREILSLMVKCPNE-
:: ::::::..:. . ... :: . .: ......: :: :::::.:.. : ::
NP_003 SPKQTECGHRFCESCMAALLSSSSPKCTACQESIVKDKVFKDNCCKREILALQIYCRNES
70 80 90 100 110 120
140 150 160 170 180 190
pF1KB5 -GCLHKMELRHLEDH-QAHCEFALMDC--PQCQRPFQKFHINIHILKDCPRRQVSCDNCA
:: ... : :: : . :.: . : :.:.. . . :. : : :...:..:
NP_003 RGCAEQLMLGHLLVHLKNDCHFEELPCVRPDCKEKVLRKDLRDHVEKACKYREATCSHCK
130 140 150 160 170 180
200 210 220 230 240 250
pF1KB5 ASMAFEDKEIH-DQNCPLANVICEY-CNT-ILIREQMPNHYDLDCPTAPIPCTFSTFGCH
... . . : : .:: . : : . :.. :.: .. : . .: .:: :.:. .::
NP_003 SQVPMIALQKHEDTDCPCVVVSCPHKCSVQTLLRSELSAHLS-ECVNAPSTCSFKRYGCV
190 200 210 220 230 240
260 270 280 290 300
pF1KB5 EKMQRNHLARHLQENTQSHMRMLAQAVHSL----SVIPDSGYISE--VRNFQETIHQLEG
. ... : .. .:. .: . .:: :.. . . .. ...... : ..:
NP_003 FQGTNQQIKAHEASSAVQHVNLLKEWSNSLEKKVSLLQNESVEKNKSIQSLHNQICSFEI
250 260 270 280 290 300
310 320 330 340
pF1KB5 RLVRQDHQIRELTAKM-------ETQSMYVSELKRTIR-----------------TLEDK
.. :: ...:. .:. ..:. ..:: . :: .:...
NP_003 EIERQKEMLRNNESKILHLQRVIDSQAEKLKELDKEIRPFRQNWEEADSMKSSVESLQNR
310 320 330 340 350 360
350
pF1KB5 VAEIE-----AQQC----------------------------------------NGIYIW
:.:.: : : ::. ::
NP_003 VTELESVDKSAGQVARNTGLLESQLSRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIW
370 380 390 400 410 420
360 370 380 390 400 410
pF1KB5 KIGNFGMHLKCQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCANYISLFVHTMQ
:: .. . . : . ..: :::: :::.: :..:. . ....::: :.
NP_003 KIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGK-GTHLSLFFVIMR
430 440 450 460 470
420 430 440 450 460 470
pF1KB5 GEYDSHLPWPFQGTIRLTILDQSEAPVRQNHEEIMDAKPELLAFQRPTIPRNPKGFGYVT
::::. :::::. . : ..::. . :.. . . :. .:..::
NP_003 GEYDALLPWPFKQKVTLMLMDQGSS--RRHLGDAFKPDPNSSSFKKPTGEMNIASGCPVF
480 490 500 510 520 530
480 490 500 510 520
pF1KB5 FMHLEALRQRTFIKDDTLLVRCEVSTRFDMGSLRREGFQPRSTDAGV
NP_003 VAQTVLENGTYIKDDTIFIKVIVDTSDLPDP
540 550 560
522 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:46:51 2016 done: Thu Nov 3 17:46:52 2016
Total Scan time: 9.320 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]