Result of FASTA (omim) for
pF1KB5593
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5593, 1863 aa
1>>>pF1KB5593 1863 - 1863 aa - 1863 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.3938+/-0.0006; mu= 10.0320+/- 0.037
mean_var=193.1792+/-40.866, 0's: 0 Z-trim(112.0): 156 B-trim: 1045 in 1/51
Lambda= 0.092277
statistics sampled from 20535 (20720) to 20535 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.576), E-opt: 0.2 (0.243), width: 16
Scan time: 17.540
The best scores are: opt bits E(85289)
NP_009225 (OMIM: 113705,114480,604370,614320) brea (1863) 12231 1643.1 0
NP_009228 (OMIM: 113705,114480,604370,614320) brea (1816) 11906 1599.9 0
NP_009231 (OMIM: 113705,114480,604370,614320) brea (1884) 9496 1279.0 0
NP_009229 (OMIM: 113705,114480,604370,614320) brea ( 759) 3336 458.7 1e-127
NP_009230 (OMIM: 113705,114480,604370,614320) brea ( 699) 2733 378.4 1.4e-103
XP_011512568 (OMIM: 609316) PREDICTED: E3 ubiquiti ( 261) 211 42.3 0.0076
XP_016869319 (OMIM: 251200,607117) PREDICTED: micr ( 830) 218 43.6 0.0098
>>NP_009225 (OMIM: 113705,114480,604370,614320) breast c (1863 aa)
initn: 12231 init1: 12231 opt: 12231 Z-score: 8808.3 bits: 1643.1 E(85289): 0
Smith-Waterman score: 12231; 100.0% identity (100.0% similar) in 1863 aa overlap (1-1863:1-1863)
10 20 30 40 50 60
pF1KB5 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB5 FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB5 NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB5 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB5 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB5 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB5 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB5 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB5 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB5 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB5 DLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSK
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB5 CPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 CPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEG
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB5 TPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTT
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB5 DTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLI
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB5 TEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDV
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB5 VNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTL
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB5 GTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPH
1810 1820 1830 1840 1850 1860
pF1KB5 SHY
:::
NP_009 SHY
>>NP_009228 (OMIM: 113705,114480,604370,614320) breast c (1816 aa)
initn: 11906 init1: 11906 opt: 11906 Z-score: 8574.6 bits: 1599.9 E(85289): 0
Smith-Waterman score: 11906; 100.0% identity (100.0% similar) in 1816 aa overlap (48-1863:1-1816)
20 30 40 50 60 70
pF1KB5 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST
::::::::::::::::::::::::::::::
NP_009 MLKLLNQKKGPSQCPLCKNDITKRSLQEST
10 20 30
80 90 100 110 120 130
pF1KB5 RFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 LQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYC
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB5 SVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERH
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB5 PEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQ
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB5 HNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB5 SIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVDEYSGSSEKIDLLASDPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVDEYSGSSEKIDLLASDPH
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB5 EALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB5 LTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKT
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB5 KGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSST
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB5 RHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATG
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB5 AKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKEFVNPSLPREEKEEKLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 AKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKEFVNPSLPREEKEEKLET
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB5 VKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQESISLLEVSTLGKAKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQESISLLEVSTLGKAKTE
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB5 PNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHSRETSIEMEESELDAQYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHSRETSIEMEESELDAQYL
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB5 QNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVTFECEQKEENQGKNESNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVTFECEQKEENQGKNESNI
820 830 840 850 860 870
920 930 940 950 960 970
pF1KB5 KPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRGNETGLITPNKHGLLQNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRGNETGLITPNKHGLLQNP
880 890 900 910 920 930
980 990 1000 1010 1020 1030
pF1KB5 YRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIPSTVSTISRNNIRENVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 YRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIPSTVSTISRNNIRENVFK
940 950 960 970 980 990
1040 1050 1060 1070 1080 1090
pF1KB5 EASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKLNAMLRLGVLQPEVYKQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKLNAMLRLGVLQPEVYKQS
1000 1010 1020 1030 1040 1050
1100 1110 1120 1130 1140 1150
pF1KB5 LPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDG
1060 1070 1080 1090 1100 1110
1160 1170 1180 1190 1200 1210
pF1KB5 EIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLS
1120 1130 1140 1150 1160 1170
1220 1230 1240 1250 1260 1270
pF1KB5 SEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILA
1180 1190 1200 1210 1220 1230
1280 1290 1300 1310 1320 1330
pF1KB5 KASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSD
1240 1250 1260 1270 1280 1290
1340 1350 1360 1370 1380 1390
pF1KB5 KELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQR
1300 1310 1320 1330 1340 1350
1400 1410 1420 1430 1440 1450
pF1KB5 DTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTS
1360 1370 1380 1390 1400 1410
1460 1470 1480 1490 1500 1510
pF1KB5 QKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSL
1420 1430 1440 1450 1460 1470
1520 1530 1540 1550 1560 1570
pF1KB5 QNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPES
1480 1490 1500 1510 1520 1530
1580 1590 1600 1610 1620 1630
pF1KB5 DPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKP
1540 1550 1560 1570 1580 1590
1640 1650 1660 1670 1680 1690
pF1KB5 ELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVC
1600 1610 1620 1630 1640 1650
1700 1710 1720 1730 1740 1750
pF1KB5 ERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQD
1660 1670 1680 1690 1700 1710
1760 1770 1780 1790 1800 1810
pF1KB5 RKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTE
1720 1730 1740 1750 1760 1770
1820 1830 1840 1850 1860
pF1KB5 DNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY
::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY
1780 1790 1800 1810
>>NP_009231 (OMIM: 113705,114480,604370,614320) breast c (1884 aa)
initn: 9483 init1: 9483 opt: 9496 Z-score: 6840.5 bits: 1279.0 E(85289): 0
Smith-Waterman score: 12175; 98.8% identity (98.9% similar) in 1884 aa overlap (1-1863:1-1884)
10 20 30 40 50 60
pF1KB5 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB5 FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB5 NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB5 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB5 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB5 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB5 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB5 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB5 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB5 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE
1390 1400 1410 1420 1430 1440
1450 1460 1470
pF1KB5 DLRNPEQSTSEK---------------------AVLTSQKSSEYPISQNPEGLSADKFEV
:::::::::::: .::::::::::::::::::::::::::
NP_009 DLRNPEQSTSEKDSHIHGQRNNSMFSKRPREHISVLTSQKSSEYPISQNPEGLSADKFEV
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KB5 SADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQL
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KB5 EESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSA
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KB5 LKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTP
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KB5 EEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 EEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWV
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KB5 TQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 TQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQ
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KB5 LEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVL
1810 1820 1830 1840 1850 1860
1840 1850 1860
pF1KB5 DSVALYQCQELDTYLIPQIPHSHY
::::::::::::::::::::::::
NP_009 DSVALYQCQELDTYLIPQIPHSHY
1870 1880
>>NP_009229 (OMIM: 113705,114480,604370,614320) breast c (759 aa)
initn: 4462 init1: 2750 opt: 3336 Z-score: 2414.0 bits: 458.7 E(85289): 1e-127
Smith-Waterman score: 3336; 72.0% identity (83.3% similar) in 765 aa overlap (1108-1863:6-759)
1080 1090 1100 1110 1120 1130
pF1KB5 PKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPM
.. .: ..:..... . . . ...:.
NP_009 MDLSALRVEEVQNVINAMQKILECPICLELIKEPV
10 20 30
1140 1150 1160 1170 1180 1190
pF1KB5 GSSHASQVCSETPDDLLDDGEIKEDTSFAENDI-KES---SAVFSKSVQKGELSRSPSPF
... :. ::.. . . . .::: :.: :. ::. :. :: . :
NP_009 STKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVE--ELLKIICAF
40 50 60 70 80 90
1200 1210 1220 1230 1240
pF1KB5 ---THTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGK--VNNIPSQSTRHSTVA
: . :..: ::: ..: :.:..: . . . .: ... : . . . :
NP_009 QLDTGLEYANSYNF-AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSL
100 110 120 130 140 150
1250 1260 1270 1280 1290 1300
pF1KB5 TECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTA
. ::. : :. .. ...: . .:. ::.: .:. : .:: ..:
NP_009 SVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDS---SEDTVNKATYCSVGDQELLQITP
160 170 180 190 200
1310 1320 1330 1340 1350 1360
pF1KB5 NTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEA
. .:.: . . :.:. . : .... :... : :. :. .. :::
NP_009 Q-GTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTT---EKRAAERHPEKYQGEA
210 220 230 240 250 260
1370 1380 1390 1400 1410 1420
pF1KB5 ASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNS
270 280 290 300 310 320
1430 1440 1450 1460 1470 1480
pF1KB5 YPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKN
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
NP_009 YPSIISDSSALEDLRNPEQSTSEK-VLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKN
330 340 350 360 370 380
1490 1500 1510 1520 1530 1540
pF1KB5 KEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLT
390 400 410 420 430 440
1550 1560 1570 1580 1590 1600
pF1KB5 ETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVA
450 460 470 480 490 500
1610 1620 1630 1640 1650 1660
pF1KB5 ESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKF
510 520 530 540 550 560
1670 1680 1690 1700 1710 1720
pF1KB5 ARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKM
570 580 590 600 610 620
1730 1740 1750 1760 1770 1780
pF1KB5 LNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCG
630 640 650 660 670 680
1790 1800 1810 1820 1830 1840
pF1KB5 ASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQ
690 700 710 720 730 740
1850 1860
pF1KB5 ELDTYLIPQIPHSHY
:::::::::::::::
NP_009 ELDTYLIPQIPHSHY
750
>>NP_009230 (OMIM: 113705,114480,604370,614320) breast c (699 aa)
initn: 3859 init1: 2147 opt: 2733 Z-score: 1980.6 bits: 378.4 E(85289): 1.4e-103
Smith-Waterman score: 2733; 68.5% identity (81.1% similar) in 679 aa overlap (1108-1777:6-673)
1080 1090 1100 1110 1120 1130
pF1KB5 PKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPM
.. .: ..:..... . . . ...:.
NP_009 MDLSALRVEEVQNVINAMQKILECPICLELIKEPV
10 20 30
1140 1150 1160 1170 1180 1190
pF1KB5 GSSHASQVCSETPDDLLDDGEIKEDTSFAENDI-KES---SAVFSKSVQKGELSRSPSPF
... :. ::.. . . . .::: :.: :. ::. :. :: . :
NP_009 STKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVE--ELLKIICAF
40 50 60 70 80 90
1200 1210 1220 1230 1240
pF1KB5 ---THTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGK--VNNIPSQSTRHSTVA
: . :..: ::: ..: :.:..: . . . .: ... : . . . :
NP_009 QLDTGLEYANSYNF-AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSL
100 110 120 130 140 150
1250 1260 1270 1280 1290 1300
pF1KB5 TECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTA
. ::. : :. .. ...: . .:. ::.: .:. : .:: ..:
NP_009 SVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDS---SEDTVNKATYCSVGDQELLQITP
160 170 180 190 200
1310 1320 1330 1340 1350 1360
pF1KB5 NTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEA
. .:.: . . :.:. . : .... :... : :. :. .. :::
NP_009 Q-GTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTT---EKRAAERHPEKYQGEA
210 220 230 240 250 260
1370 1380 1390 1400 1410 1420
pF1KB5 ASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNS
270 280 290 300 310 320
1430 1440 1450 1460 1470 1480
pF1KB5 YPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKN
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
NP_009 YPSIISDSSALEDLRNPEQSTSEK-VLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKN
330 340 350 360 370 380
1490 1500 1510 1520 1530 1540
pF1KB5 KEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 KEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLT
390 400 410 420 430 440
1550 1560 1570 1580 1590 1600
pF1KB5 ETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVA
450 460 470 480 490 500
1610 1620 1630 1640 1650 1660
pF1KB5 ESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKF
510 520 530 540 550 560
1670 1680 1690 1700 1710 1720
pF1KB5 ARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 ARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKM
570 580 590 600 610 620
1730 1740 1750 1760 1770 1780
pF1KB5 LNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCG
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTGCPPNCGCAAR
630 640 650 660 670 680
1790 1800 1810 1820 1830 1840
pF1KB5 ASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQ
NP_009 CLDRGQWLPCNWADV
690
>>XP_011512568 (OMIM: 609316) PREDICTED: E3 ubiquitin-pr (261 aa)
initn: 227 init1: 191 opt: 211 Z-score: 172.0 bits: 42.3 E(85289): 0.0076
Smith-Waterman score: 220; 32.0% identity (65.0% similar) in 103 aa overlap (15-117:7-98)
10 20 30 40 50 60
pF1KB5 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
.: .:. . :::::.....::. : : :: :. .. . . : .
XP_011 MASGQFVNKLQEEVICPICLDILQKPVTIDCGHNFCLKCITQIGETSCGFFK
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
:::::... : .. ::..:...:.. : :.: :. . .:: . :.:
XP_011 CPLCKTSVRKNAI----RFNSLLRNLVEKIQALQ-------ASEVQSKRKEATCPRHQEM
60 70 80 90 100
130 140 150 160 170 180
pF1KB5 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
XP_011 FHYFCEDDGKFLCFVCRESKDHKSHNVSLIEEAAQNYQGQIQEQIQVLQQKEKETVQVKA
110 120 130 140 150 160
>>XP_016869319 (OMIM: 251200,607117) PREDICTED: microcep (830 aa)
initn: 150 init1: 113 opt: 218 Z-score: 170.1 bits: 43.6 E(85289): 0.0098
Smith-Waterman score: 218; 19.7% identity (49.4% similar) in 695 aa overlap (1163-1820:163-820)
1140 1150 1160 1170 1180 1190
pF1KB5 LEQPMGSSHASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSP
: : . .. ::. .. . : .. ::
XP_016 KMAKELQRQKTNLDDDVPILLFESNGSLIYTPTIEINSRHHSAMEKRLQEMKEKRENLSP
140 150 160 170 180 190
1200 1210 1220 1230 1240 1250
pF1KB5 FTHTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECL
. . :.. ...: . :.: .. : .. . : . ::. :
XP_016 TSSQMIQQSHDNPSNSLCEAPLNIS---RDTLCSDEYFAGGL---------HSSFDDLCG
200 210 220 230 240
1260 1270 1280 1290 1300
pF1KB5 SKNTEENLLSLKNSLND-----CSNQVILAKASQEHH---LSEETKCSASLFSSQCSELE
... .. .:..:.:: : ....: ::.. : ... : : . : :. :. :
XP_016 NSGCGNQERKLEGSINDIKSDVCISSLVL-KANNIHSSPSFTHLDKSSPQKFLSNLSK-E
250 260 270 280 290
1310 1320 1330 1340 1350 1360
pF1KB5 DLTANTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSN
... . : . ..:: .:. . .: .: : ... .: . .
XP_016 EINLQRNIAGKVVTPDQKQAAGMSQET---FEEKYRLSPTLSSTKGHLLIHSRPRSSSVK
300 310 320 330 340 350
1370 1380 1390 1400 1410
pF1KB5 LGEAASGCESETSVSEDCS-GLSSQSDILTTQQ----RDTMQHNLIKLQQEMAELEAVLE
... : :.. .: :. :.. .:. : .: .:: . .. :. .
XP_016 RKRVSHG--SHSPPKEKCKRKRSTRRSIMPRLQLCRSEDRLQHVAGPALEALSCGESSYD
360 370 380 390 400 410
1420 1430 1440 1450 1460 1470
pF1KB5 QHGSQPSN---SYPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQ----NPEGL
.. : :.: : . : : . .: : : ... ....: . .:. . .
XP_016 DYFS-PDNLKERYSENLPPESQLPS--SPAQ-LSCRSLSKKERTSIFEMSDFSCVGKKTR
420 430 440 450 460
1480 1490 1500 1510 1520 1530
pF1KB5 SADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVV
..: . .: . .: : . : . :.: . . .. : . .. : . .
XP_016 TVDITNFTAKTISSPRKTGNGEGRATSSCVTSAPEEALRCCRQAGKEDACPEGNGF--SY
470 480 490 500 510 520
1540 1550 1560 1570 1580
pF1KB5 DVEEQQLEESGPHDLT--ETSYLPRQDLEGTPYLESG--ISLFSDDPESDPSEDRAPESA
.:. : .. ::: : : .. : .. : .:.. :.. . .. :
XP_016 TIEDPALPKGHDDDLTPLEGSLEEMKEAVGLKSTQNKGTTSKISNSSEGEAQSEHEPCFI
530 540 550 560 570 580
1590 1600 1610 1620 1630 1640
pF1KB5 RVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNK
:. .:: . . :... . : . . ..... . . . :: : . .
XP_016 VDCNMETSTEEKENLPGGYSGSVKNRPTRHDVLDDSCDGFKDLI-KPHEELKKSGRGKKP
590 600 610 620 630 640
1650 1660 1670 1680 1690 1700
pF1KB5 RMSMVVSGLTPEEFMLVYKFARK-HHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGI
..:.... :. .: . . : . .... . : ::::. :::. .:::
XP_016 TRTLVMTSMPSEKQNVVIQVVDKLKGFSIAPDVCETTTHVLSGKPL-----RTLNVLLGI
650 660 670 680 690 700
1710 1720 1730 1740 1750 1760
pF1KB5 AGGKWVVSYFWVTQSIKERKMLNEHDFEVR-----GDVVNGRNH--QGPKRARESQDRKI
: : ::.:: :: :.. . ..:. ::. . . .. : :: :. .
XP_016 ARGCWVLSYDWVLWSLELGHWISEEPFELSHHFPAAPLCRSECHLSAGPYRGT------L
710 720 730 740 750
1770 1780 1790 1800 1810
pF1KB5 FRGLEICCYGPFTNMPTDQLEWMVQLCGASV--VKELSSFTLG--TGVHPIVV-VQPDAW
: .: .. :. .: .:.:::. : : . .:...: .: . .: . :
XP_016 FADQPAMFVSPASSPPVAKLCELVHLCGGRVSQVPRQASIVIGPYSGKKKATVKYLSEKW
760 770 780 790 800 810
1820 1830 1840 1850 1860
pF1KB5 TEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY
. . :
XP_016 VLEPGALADTLDVAY
820 830
1863 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:02:40 2016 done: Wed Nov 2 23:02:43 2016
Total Scan time: 17.540 Total Display time: 0.650
Function used was FASTA [36.3.4 Apr, 2011]