Result of FASTA (ccds) for
pF1KB5593
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5593, 1863 aa
1>>>pF1KB5593 1863 - 1863 aa - 1863 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.5819+/-0.00133; mu= 15.0592+/- 0.081
mean_var=171.9828+/-35.568, 0's: 0 Z-trim(104.5): 112 B-trim: 0 in 0/50
Lambda= 0.097798
statistics sampled from 7848 (7957) to 7848 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.579), E-opt: 0.2 (0.244), width: 16
Scan time: 5.340
The best scores are: opt bits E(32554)
CCDS11453.1 BRCA1 gene_id:672|Hs108|chr17 (1863) 12231 1740.1 0
CCDS11459.2 BRCA1 gene_id:672|Hs108|chr17 (1816) 11906 1694.3 0
CCDS11456.2 BRCA1 gene_id:672|Hs108|chr17 (1884) 9496 1354.2 0
CCDS11454.2 BRCA1 gene_id:672|Hs108|chr17 ( 759) 3336 484.8 5.4e-136
CCDS11455.2 BRCA1 gene_id:672|Hs108|chr17 ( 699) 2733 399.7 2.1e-110
>>CCDS11453.1 BRCA1 gene_id:672|Hs108|chr17 (1863 aa)
initn: 12231 init1: 12231 opt: 12231 Z-score: 9332.5 bits: 1740.1 E(32554): 0
Smith-Waterman score: 12231; 100.0% identity (100.0% similar) in 1863 aa overlap (1-1863:1-1863)
10 20 30 40 50 60
pF1KB5 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB5 FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB5 NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB5 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB5 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB5 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB5 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB5 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB5 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB5 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB5 DLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSK
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB5 CPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 CPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEG
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB5 TPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTT
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB5 DTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLI
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB5 TEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDV
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB5 VNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTL
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB5 GTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPH
1810 1820 1830 1840 1850 1860
pF1KB5 SHY
:::
CCDS11 SHY
>>CCDS11459.2 BRCA1 gene_id:672|Hs108|chr17 (1816 aa)
initn: 11906 init1: 11906 opt: 11906 Z-score: 9084.8 bits: 1694.3 E(32554): 0
Smith-Waterman score: 11906; 100.0% identity (100.0% similar) in 1816 aa overlap (48-1863:1-1816)
20 30 40 50 60 70
pF1KB5 MQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQEST
::::::::::::::::::::::::::::::
CCDS11 MLKLLNQKKGPSQCPLCKNDITKRSLQEST
10 20 30
80 90 100 110 120 130
pF1KB5 RFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKDEVSIIQSMGYRNRAKRL
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 LQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDSSEDTVNKATYC
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB5 SVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTTEKRAAERH
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB5 PEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLARSQ
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB5 HNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPCSENPRDTEDVPWITLNS
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB5 SIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVDEYSGSSEKIDLLASDPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVDEYSGSSEKIDLLASDPH
340 350 360 370 380 390
440 450 460 470 480 490
pF1KB5 EALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTENLIIGAFVTEPQIIQERP
400 410 420 430 440 450
500 510 520 530 540 550
pF1KB5 LTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTEQNGQVMNITNSGHENKT
460 470 480 490 500 510
560 570 580 590 600 610
pF1KB5 KGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNIHNSKAPKKNRLRRKSST
520 530 540 550 560 570
620 630 640 650 660 670
pF1KB5 RHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPVRHSRNLQLMEGKEPATG
580 590 600 610 620 630
680 690 700 710 720 730
pF1KB5 AKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKEFVNPSLPREEKEEKLET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 AKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKEFVNPSLPREEKEEKLET
640 650 660 670 680 690
740 750 760 770 780 790
pF1KB5 VKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQESISLLEVSTLGKAKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQESISLLEVSTLGKAKTE
700 710 720 730 740 750
800 810 820 830 840 850
pF1KB5 PNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHSRETSIEMEESELDAQYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHSRETSIEMEESELDAQYL
760 770 780 790 800 810
860 870 880 890 900 910
pF1KB5 QNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVTFECEQKEENQGKNESNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVTFECEQKEENQGKNESNI
820 830 840 850 860 870
920 930 940 950 960 970
pF1KB5 KPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRGNETGLITPNKHGLLQNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRGNETGLITPNKHGLLQNP
880 890 900 910 920 930
980 990 1000 1010 1020 1030
pF1KB5 YRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIPSTVSTISRNNIRENVFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 YRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIPSTVSTISRNNIRENVFK
940 950 960 970 980 990
1040 1050 1060 1070 1080 1090
pF1KB5 EASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKLNAMLRLGVLQPEVYKQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKLNAMLRLGVLQPEVYKQS
1000 1010 1020 1030 1040 1050
1100 1110 1120 1130 1140 1150
pF1KB5 LPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSSHASQVCSETPDDLLDDG
1060 1070 1080 1090 1100 1110
1160 1170 1180 1190 1200 1210
pF1KB5 EIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQGYRRGAKKLESSEENLS
1120 1130 1140 1150 1160 1170
1220 1230 1240 1250 1260 1270
pF1KB5 SEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENLLSLKNSLNDCSNQVILA
1180 1190 1200 1210 1220 1230
1280 1290 1300 1310 1320 1330
pF1KB5 KASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGSSKQMRHQSESQGVGLSD
1240 1250 1260 1270 1280 1290
1340 1350 1360 1370 1380 1390
pF1KB5 KELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSEDCSGLSSQSDILTTQQR
1300 1310 1320 1330 1340 1350
1400 1410 1420 1430 1440 1450
pF1KB5 DTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALEDLRNPEQSTSEKAVLTS
1360 1370 1380 1390 1400 1410
1460 1470 1480 1490 1500 1510
pF1KB5 QKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QKSSEYPISQNPEGLSADKFEVSADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSL
1420 1430 1440 1450 1460 1470
1520 1530 1540 1550 1560 1570
pF1KB5 QNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QNRNYPSQEELIKVVDVEEQQLEESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPES
1480 1490 1500 1510 1520 1530
1580 1590 1600 1610 1620 1630
pF1KB5 DPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DPSEDRAPESARVGNIPSSTSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKP
1540 1550 1560 1570 1580 1590
1640 1650 1660 1670 1680 1690
pF1KB5 ELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ELTASTERVNKRMSMVVSGLTPEEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVC
1600 1610 1620 1630 1640 1650
1700 1710 1720 1730 1740 1750
pF1KB5 ERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQD
1660 1670 1680 1690 1700 1710
1760 1770 1780 1790 1800 1810
pF1KB5 RKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RKIFRGLEICCYGPFTNMPTDQLEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTE
1720 1730 1740 1750 1760 1770
1820 1830 1840 1850 1860
pF1KB5 DNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY
::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DNGFHAIGQMCEAPVVTREWVLDSVALYQCQELDTYLIPQIPHSHY
1780 1790 1800 1810
>>CCDS11456.2 BRCA1 gene_id:672|Hs108|chr17 (1884 aa)
initn: 9483 init1: 9483 opt: 9496 Z-score: 7246.9 bits: 1354.2 E(32554): 0
Smith-Waterman score: 12175; 98.8% identity (98.9% similar) in 1884 aa overlap (1-1863:1-1884)
10 20 30 40 50 60
pF1KB5 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MDLSALRVEEVQNVINAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 CPLCKNDITKRSLQESTRFSQLVEELLKIICAFQLDTGLEYANSYNFAKKENNSPEHLKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EVSIIQSMGYRNRAKRLLQSEPENPSLQETSLSVQLSNLGTVRTLRTKQRIQPQKTSVYI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ELGSDSSEDTVNKATYCSVGDQELLQITPQGTRDEISLDSAKKAACEFSETDVTNTEHHQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 PSNNDLNTTEKRAAERHPEKYQGSSVSNLHVEPCGTNTHASSLQHENSSLLLTKDRMNVE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KAEFCNKSKQPGLARSQHNRWAGSKETCNDRRTPSTEKKVDLNADPLCERKEWNKQKLPC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SENPRDTEDVPWITLNSSIQKVNEWFSRSDELLGSDDSHDGESESNAKVADVLDVLNEVD
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EYSGSSEKIDLLASDPHEALICKSERVHSKSVESNIEDKIFGKTYRKKASLPNLSHVTEN
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LIIGAFVTEPQIIQERPLTNKLKRKRRPTSGLHPEDFIKKADLAVQKTPEMINQGTNQTE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 QNGQVMNITNSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSSISNMELELNI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB5 HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEIKKKKYNQMPV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB5 RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RHSRNLQLMEGKEPATGAKKSNKPNEQTSKRHDSDTFPELKLTNAPGSFTKCSNTSELKE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB5 FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FVNPSLPREEKEEKLETVKVSNNAEDPKDLMLSGERVLQTERSVESSSISLVPGTDYGTQ
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB5 ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ESISLLEVSTLGKAKTEPNKCVSQCAAFENPKGLIHGCSKDNRNDTEGFKYPLGHEVNHS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB5 RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RETSIEMEESELDAQYLQNTFKVSKRQSFAPFSNPGNAEEECATFSAHSGSLKKQSPKVT
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB5 FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 FECEQKEENQGKNESNIKPVQTVNITAGFPVVGQKDKPVDNAKCSIKGGSRFCLSSQFRG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB5 NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NETGLITPNKHGLLQNPYRIPPLFPIKSFVKTKCKKNLLEENFEEHSMSPEREMGNENIP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB5 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 STVSTISRNNIRENVFKEASSSNINEVGSSTNEVGSSINEIGSSDENIQAELGRNRGPKL
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB5 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPMGSS
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB5 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HASQVCSETPDDLLDDGEIKEDTSFAENDIKESSAVFSKSVQKGELSRSPSPFTHTHLAQ
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB5 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 GYRRGAKKLESSEENLSSEDEELPCFQHLLFGKVNNIPSQSTRHSTVATECLSKNTEENL
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB5 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTANTNTQDPFLIGS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB5 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEAASGCESETSVSE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB5 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 DCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNSYPSIISDSSALE
1390 1400 1410 1420 1430 1440
1450 1460 1470
pF1KB5 DLRNPEQSTSEK---------------------AVLTSQKSSEYPISQNPEGLSADKFEV
:::::::::::: .::::::::::::::::::::::::::
CCDS11 DLRNPEQSTSEKDSHIHGQRNNSMFSKRPREHISVLTSQKSSEYPISQNPEGLSADKFEV
1450 1460 1470 1480 1490 1500
1480 1490 1500 1510 1520 1530
pF1KB5 SADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 SADSSTSKNKEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQL
1510 1520 1530 1540 1550 1560
1540 1550 1560 1570 1580 1590
pF1KB5 EESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EESGPHDLTETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSA
1570 1580 1590 1600 1610 1620
1600 1610 1620 1630 1640 1650
pF1KB5 LKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTP
1630 1640 1650 1660 1670 1680
1660 1670 1680 1690 1700 1710
pF1KB5 EEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 EEFMLVYKFARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWV
1690 1700 1710 1720 1730 1740
1720 1730 1740 1750 1760 1770
pF1KB5 TQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 TQSIKERKMLNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQ
1750 1760 1770 1780 1790 1800
1780 1790 1800 1810 1820 1830
pF1KB5 LEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LEWMVQLCGASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVL
1810 1820 1830 1840 1850 1860
1840 1850 1860
pF1KB5 DSVALYQCQELDTYLIPQIPHSHY
::::::::::::::::::::::::
CCDS11 DSVALYQCQELDTYLIPQIPHSHY
1870 1880
>>CCDS11454.2 BRCA1 gene_id:672|Hs108|chr17 (759 aa)
initn: 4462 init1: 2750 opt: 3336 Z-score: 2555.0 bits: 484.8 E(32554): 5.4e-136
Smith-Waterman score: 3336; 72.0% identity (83.3% similar) in 765 aa overlap (1108-1863:6-759)
1080 1090 1100 1110 1120 1130
pF1KB5 PKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPM
.. .: ..:..... . . . ...:.
CCDS11 MDLSALRVEEVQNVINAMQKILECPICLELIKEPV
10 20 30
1140 1150 1160 1170 1180 1190
pF1KB5 GSSHASQVCSETPDDLLDDGEIKEDTSFAENDI-KES---SAVFSKSVQKGELSRSPSPF
... :. ::.. . . . .::: :.: :. ::. :. :: . :
CCDS11 STKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVE--ELLKIICAF
40 50 60 70 80 90
1200 1210 1220 1230 1240
pF1KB5 ---THTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGK--VNNIPSQSTRHSTVA
: . :..: ::: ..: :.:..: . . . .: ... : . . . :
CCDS11 QLDTGLEYANSYNF-AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSL
100 110 120 130 140 150
1250 1260 1270 1280 1290 1300
pF1KB5 TECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTA
. ::. : :. .. ...: . .:. ::.: .:. : .:: ..:
CCDS11 SVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDS---SEDTVNKATYCSVGDQELLQITP
160 170 180 190 200
1310 1320 1330 1340 1350 1360
pF1KB5 NTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEA
. .:.: . . :.:. . : .... :... : :. :. .. :::
CCDS11 Q-GTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTT---EKRAAERHPEKYQGEA
210 220 230 240 250 260
1370 1380 1390 1400 1410 1420
pF1KB5 ASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNS
270 280 290 300 310 320
1430 1440 1450 1460 1470 1480
pF1KB5 YPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKN
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
CCDS11 YPSIISDSSALEDLRNPEQSTSEK-VLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKN
330 340 350 360 370 380
1490 1500 1510 1520 1530 1540
pF1KB5 KEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLT
390 400 410 420 430 440
1550 1560 1570 1580 1590 1600
pF1KB5 ETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVA
450 460 470 480 490 500
1610 1620 1630 1640 1650 1660
pF1KB5 ESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKF
510 520 530 540 550 560
1670 1680 1690 1700 1710 1720
pF1KB5 ARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKM
570 580 590 600 610 620
1730 1740 1750 1760 1770 1780
pF1KB5 LNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCG
630 640 650 660 670 680
1790 1800 1810 1820 1830 1840
pF1KB5 ASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQ
690 700 710 720 730 740
1850 1860
pF1KB5 ELDTYLIPQIPHSHY
:::::::::::::::
CCDS11 ELDTYLIPQIPHSHY
750
>>CCDS11455.2 BRCA1 gene_id:672|Hs108|chr17 (699 aa)
initn: 3859 init1: 2147 opt: 2733 Z-score: 2095.6 bits: 399.7 E(32554): 2.1e-110
Smith-Waterman score: 2733; 68.5% identity (81.1% similar) in 679 aa overlap (1108-1777:6-673)
1080 1090 1100 1110 1120 1130
pF1KB5 PKLNAMLRLGVLQPEVYKQSLPGSNCKHPEIKKQEYEEVVQTVNTDFSPYLISDNLEQPM
.. .: ..:..... . . . ...:.
CCDS11 MDLSALRVEEVQNVINAMQKILECPICLELIKEPV
10 20 30
1140 1150 1160 1170 1180 1190
pF1KB5 GSSHASQVCSETPDDLLDDGEIKEDTSFAENDI-KES---SAVFSKSVQKGELSRSPSPF
... :. ::.. . . . .::: :.: :. ::. :. :: . :
CCDS11 STKCDHIFCKFCMLKLLNQKKGPSQCPLCKNDITKRSLQESTRFSQLVE--ELLKIICAF
40 50 60 70 80 90
1200 1210 1220 1230 1240
pF1KB5 ---THTHLAQGYRRGAKKLESSEENLSSEDEELPCFQHLLFGK--VNNIPSQSTRHSTVA
: . :..: ::: ..: :.:..: . . . .: ... : . . . :
CCDS11 QLDTGLEYANSYNF-AKKENNSPEHLKDEVSIIQSMGYRNRAKRLLQSEPENPSLQETSL
100 110 120 130 140 150
1250 1260 1270 1280 1290 1300
pF1KB5 TECLSKNTEENLLSLKNSLNDCSNQVILAKASQEHHLSEETKCSASLFSSQCSELEDLTA
. ::. : :. .. ...: . .:. ::.: .:. : .:: ..:
CCDS11 SVQLSNLGTVRTLRTKQRIQPQKTSVYIELGSDS---SEDTVNKATYCSVGDQELLQITP
160 170 180 190 200
1310 1320 1330 1340 1350 1360
pF1KB5 NTNTQDPFLIGSSKQMRHQSESQGVGLSDKELVSDDEERGTGLEENNQEEQSMDSNLGEA
. .:.: . . :.:. . : .... :... : :. :. .. :::
CCDS11 Q-GTRDEISLDSAKKAACEFSETDVTNTEHHQPSNNDLNTT---EKRAAERHPEKYQGEA
210 220 230 240 250 260
1370 1380 1390 1400 1410 1420
pF1KB5 ASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ASGCESETSVSEDCSGLSSQSDILTTQQRDTMQHNLIKLQQEMAELEAVLEQHGSQPSNS
270 280 290 300 310 320
1430 1440 1450 1460 1470 1480
pF1KB5 YPSIISDSSALEDLRNPEQSTSEKAVLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKN
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
CCDS11 YPSIISDSSALEDLRNPEQSTSEK-VLTSQKSSEYPISQNPEGLSADKFEVSADSSTSKN
330 340 350 360 370 380
1490 1500 1510 1520 1530 1540
pF1KB5 KEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 KEPGVERSSPSKCPSLDDRWYMHSCSGSLQNRNYPSQEELIKVVDVEEQQLEESGPHDLT
390 400 410 420 430 440
1550 1560 1570 1580 1590 1600
pF1KB5 ETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ETSYLPRQDLEGTPYLESGISLFSDDPESDPSEDRAPESARVGNIPSSTSALKVPQLKVA
450 460 470 480 490 500
1610 1620 1630 1640 1650 1660
pF1KB5 ESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ESAQSPAAAHTTDTAGYNAMEESVSREKPELTASTERVNKRMSMVVSGLTPEEFMLVYKF
510 520 530 540 550 560
1670 1680 1690 1700 1710 1720
pF1KB5 ARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ARKHHITLTNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKM
570 580 590 600 610 620
1730 1740 1750 1760 1770 1780
pF1KB5 LNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTDQLEWMVQLCG
:::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LNEHDFEVRGDVVNGRNHQGPKRARESQDRKIFRGLEICCYGPFTNMPTGCPPNCGCAAR
630 640 650 660 670 680
1790 1800 1810 1820 1830 1840
pF1KB5 ASVVKELSSFTLGTGVHPIVVVQPDAWTEDNGFHAIGQMCEAPVVTREWVLDSVALYQCQ
CCDS11 CLDRGQWLPCNWADV
690
1863 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Wed Nov 2 23:02:39 2016 done: Wed Nov 2 23:02:40 2016
Total Scan time: 5.340 Total Display time: 0.590
Function used was FASTA [36.3.4 Apr, 2011]