Result of FASTA (omim) for
pF1KB5375
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5375, 225 aa
1>>>pF1KB5375 225 - 225 aa - 225 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0660+/-0.000373; mu= 15.5043+/- 0.023
mean_var=63.6906+/-12.750, 0's: 0 Z-trim(112.8): 41 B-trim: 815 in 1/53
Lambda= 0.160708
statistics sampled from 21791 (21832) to 21791 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.63), E-opt: 0.2 (0.256), width: 16
Scan time: 5.280
The best scores are: opt bits E(85289)
NP_000840 (OMIM: 138390) glutathione S-transferase ( 225) 1546 366.9 1.5e-101
NP_000841 (OMIM: 138333) glutathione S-transferase ( 218) 1101 263.7 1.7e-70
NP_000552 (OMIM: 138350) glutathione S-transferase ( 218) 1093 261.9 6.2e-70
NP_000842 (OMIM: 138385) glutathione S-transferase ( 218) 1083 259.6 3.1e-69
XP_005270841 (OMIM: 138385) PREDICTED: glutathione ( 218) 1083 259.6 3.1e-69
NP_000839 (OMIM: 138380) glutathione S-transferase ( 218) 1062 254.7 9e-68
NP_671489 (OMIM: 138333) glutathione S-transferase ( 195) 999 240.1 2e-63
XP_016856574 (OMIM: 138333) PREDICTED: glutathione ( 254) 999 240.1 2.5e-63
NP_001135840 (OMIM: 138380) glutathione S-transfer ( 191) 951 228.9 4.5e-60
XP_005270839 (OMIM: 138350) PREDICTED: glutathione ( 184) 896 216.2 3e-56
NP_666533 (OMIM: 138350) glutathione S-transferase ( 181) 792 192.0 5.4e-49
XP_016856576 (OMIM: 138333) PREDICTED: glutathione ( 177) 759 184.4 1.1e-46
XP_016856575 (OMIM: 138333) PREDICTED: glutathione ( 213) 657 160.8 1.6e-39
XP_005270842 (OMIM: 138385) PREDICTED: glutathione ( 114) 483 120.3 1.4e-27
XP_016856577 (OMIM: 138333) PREDICTED: glutathione ( 150) 401 101.3 9e-22
NP_000843 (OMIM: 134660) glutathione S-transferase ( 210) 372 94.7 1.3e-19
NP_000837 (OMIM: 138360) glutathione S-transferase ( 222) 218 59.0 7.3e-09
XP_011512834 (OMIM: 138360) PREDICTED: glutathione ( 222) 218 59.0 7.3e-09
NP_714543 (OMIM: 607605) glutathione S-transferase ( 222) 207 56.5 4.3e-08
NP_000838 (OMIM: 605449) glutathione S-transferase ( 222) 200 54.8 1.3e-07
NP_055300 (OMIM: 602598) hematopoietic prostagland ( 199) 197 54.1 2e-07
NP_665683 (OMIM: 138359) glutathione S-transferase ( 222) 197 54.1 2.1e-07
XP_016866283 (OMIM: 605449) PREDICTED: glutathione ( 172) 166 46.9 2.5e-05
XP_006715135 (OMIM: 605449) PREDICTED: glutathione ( 172) 166 46.9 2.5e-05
XP_005249091 (OMIM: 138359) PREDICTED: glutathione ( 225) 155 44.4 0.00019
XP_005249092 (OMIM: 605450) PREDICTED: glutathione ( 222) 152 43.7 0.0003
NP_001503 (OMIM: 605450) glutathione S-transferase ( 222) 152 43.7 0.0003
XP_005262989 (OMIM: 602598) PREDICTED: hematopoiet ( 168) 148 42.7 0.00045
XP_011512837 (OMIM: 605450) PREDICTED: glutathione ( 185) 145 42.0 0.00079
XP_011512836 (OMIM: 605450) PREDICTED: glutathione ( 185) 145 42.0 0.00079
>>NP_000840 (OMIM: 138390) glutathione S-transferase Mu (225 aa)
initn: 1546 init1: 1546 opt: 1546 Z-score: 1944.0 bits: 366.9 E(85289): 1.5e-101
Smith-Waterman score: 1546; 99.6% identity (99.6% similar) in 225 aa overlap (1-225:1-225)
10 20 30 40 50 60
pF1KB5 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
130 140 150 160 170 180
190 200 210 220
pF1KB5 EFSNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
:: ::::::::::::::::::::::::::::::::::::::::::
NP_000 EFPNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
190 200 210 220
>>NP_000841 (OMIM: 138333) glutathione S-transferase Mu (218 aa)
initn: 1101 init1: 1101 opt: 1101 Z-score: 1386.6 bits: 263.7 E(85289): 1.7e-70
Smith-Waterman score: 1101; 71.9% identity (89.4% similar) in 217 aa overlap (6-222:2-218)
10 20 30 40 50 60
pF1KB5 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
::.::::::::::::::::::.::.:::::.:: :.::::::::::. :::: ::
NP_000 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLD
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
:::::::.:: .::::::::: :::::::.:::::::::::::.:::.:: .:: :.::
NP_000 FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
: : :::::.:::::: ....::.:::: ::.:.:.::::::.::.:: .:::.:.:::
NP_000 SPDFEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLD
120 130 140 150 160 170
190 200 210 220
pF1KB5 EFSNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
: ::: :. :::.::::.::..:..: :. ...: ::::
NP_000 AFPNLKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK
180 190 200 210
>>NP_000552 (OMIM: 138350) glutathione S-transferase Mu (218 aa)
initn: 1093 init1: 1093 opt: 1093 Z-score: 1376.6 bits: 261.9 E(85289): 6.2e-70
Smith-Waterman score: 1093; 72.7% identity (88.0% similar) in 216 aa overlap (7-222:3-218)
10 20 30 40 50 60
pF1KB5 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
:.::::::::::::::::::.::.:::::.:: :.::::::::::. :::: ::
NP_000 MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLD
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
:::::::.:: .::::::::: :::::::.:::::::::::::.:::.:: . :: .::
NP_000 FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
. . :::::.:::::: .:: .: :::: ::::.:.::::::.::.:: .:::.:::::
NP_000 NPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLD
120 130 140 150 160 170
190 200 210 220
pF1KB5 EFSNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
: ::: :. :::.::::.::..:..: :. .::: ::::
NP_000 AFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
180 190 200 210
>>NP_000842 (OMIM: 138385) glutathione S-transferase Mu (218 aa)
initn: 1083 init1: 1055 opt: 1083 Z-score: 1364.1 bits: 259.6 E(85289): 3.1e-69
Smith-Waterman score: 1083; 72.2% identity (88.9% similar) in 216 aa overlap (7-222:3-218)
10 20 30 40 50 60
pF1KB5 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
:.::::::::::::::::::.::.:: ::.:: :.::::::::::. :::: ::
NP_000 MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLD
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
:::::::.:: .:::::::::::::::::.:::::::::::::.:::::: . .:.::::
NP_000 FPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
. : :::::.:::::: .:: .: :::: ::::.:.::::::.::.::..:::.:::::
NP_000 DPDFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLD
120 130 140 150 160 170
190 200 210 220
pF1KB5 EFSNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
: ::: :. :::.:.::.::..:.:: . . .: : :..:
NP_000 AFLNLKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK
180 190 200 210
>>XP_005270841 (OMIM: 138385) PREDICTED: glutathione S-t (218 aa)
initn: 1083 init1: 1055 opt: 1083 Z-score: 1364.1 bits: 259.6 E(85289): 3.1e-69
Smith-Waterman score: 1083; 72.2% identity (88.9% similar) in 216 aa overlap (7-222:3-218)
10 20 30 40 50 60
pF1KB5 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
:.::::::::::::::::::.::.:: ::.:: :.::::::::::. :::: ::
XP_005 MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLD
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
:::::::.:: .:::::::::::::::::.:::::::::::::.:::::: . .:.::::
XP_005 FPNLPYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
. : :::::.:::::: .:: .: :::: ::::.:.::::::.::.::..:::.:::::
XP_005 DPDFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLD
120 130 140 150 160 170
190 200 210 220
pF1KB5 EFSNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
: ::: :. :::.:.::.::..:.:: . . .: : :..:
XP_005 AFLNLKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK
180 190 200 210
>>NP_000839 (OMIM: 138380) glutathione S-transferase Mu (218 aa)
initn: 1062 init1: 1062 opt: 1062 Z-score: 1337.7 bits: 254.7 E(85289): 9e-68
Smith-Waterman score: 1062; 68.5% identity (88.0% similar) in 216 aa overlap (7-222:3-218)
10 20 30 40 50 60
pF1KB5 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
:.::::.::::::.::::::.::.:::::.:: :.::::::::::. :::: ::
NP_000 MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLD
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
:::::::.:: .:::::::::::::::::.:::.:.:.:: ::.::: :: : :: .:::
NP_000 FPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
. : :::::.::. :: .:: .:.:::: :: :.:.:::::..::.:..:..:.:.:::
NP_000 DPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLD
120 130 140 150 160 170
190 200 210 220
pF1KB5 EFSNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
: ::: :. :::.::::.::..:..: :. .::: ::::
NP_000 AFPNLKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK
180 190 200 210
>>NP_671489 (OMIM: 138333) glutathione S-transferase Mu (195 aa)
initn: 999 init1: 999 opt: 999 Z-score: 1259.5 bits: 240.1 E(85289): 2e-63
Smith-Waterman score: 999; 75.5% identity (90.4% similar) in 188 aa overlap (6-193:2-189)
10 20 30 40 50 60
pF1KB5 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
::.::::::::::::::::::.::.:::::.:: :.::::::::::. :::: ::
NP_671 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLD
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
:::::::.:: .::::::::: :::::::.:::::::::::::.:::.:: .:: :.::
NP_671 FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
: : :::::.:::::: ....::.:::: ::.:.:.::::::.::.:: .:::.:.:::
NP_671 SPDFEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLD
120 130 140 150 160 170
190 200 210 220
pF1KB5 EFSNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
: ::: :. :::
NP_671 AFPNLKDFISRFEVSCGIM
180 190
>>XP_016856574 (OMIM: 138333) PREDICTED: glutathione S-t (254 aa)
initn: 999 init1: 999 opt: 999 Z-score: 1257.8 bits: 240.1 E(85289): 2.5e-63
Smith-Waterman score: 999; 75.5% identity (90.4% similar) in 188 aa overlap (6-193:2-189)
10 20 30 40 50 60
pF1KB5 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
::.::::::::::::::::::.::.:::::.:: :.::::::::::. :::: ::
XP_016 MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLD
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
:::::::.:: .::::::::: :::::::.:::::::::::::.:::.:: .:: :.::
XP_016 FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
: : :::::.:::::: ....::.:::: ::.:.:.::::::.::.:: .:::.:.:::
XP_016 SPDFEKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLD
120 130 140 150 160 170
190 200 210 220
pF1KB5 EFSNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
: ::: :. :::
XP_016 AFPNLKDFISRFECSKCSPCEMSSTLILLLFTDLLLCMRQGVRHSGSCIDDCPILEMSAV
180 190 200 210 220 230
>>NP_001135840 (OMIM: 138380) glutathione S-transferase (191 aa)
initn: 951 init1: 951 opt: 951 Z-score: 1199.5 bits: 228.9 E(85289): 4.5e-60
Smith-Waterman score: 951; 70.6% identity (88.8% similar) in 187 aa overlap (7-193:3-189)
10 20 30 40 50 60
pF1KB5 MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLD
:.::::.::::::.::::::.::.:::::.:: :.::::::::::. :::: ::
NP_001 MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLD
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 FPNLPYLLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCY
:::::::.:: .:::::::::::::::::.:::.:.:.:: ::.::: :: : :: .:::
NP_001 FPNLPYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCY
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 SSDHEKLKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLD
. : :::::.::. :: .:: .:.:::: :: :.:.:::::..::.:..:..:.:.:::
NP_001 DPDFEKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLD
120 130 140 150 160 170
190 200 210 220
pF1KB5 EFSNLKAFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
: ::: :. :::
NP_001 AFPNLKDFISRFEHS
180 190
>>XP_005270839 (OMIM: 138350) PREDICTED: glutathione S-t (184 aa)
initn: 896 init1: 896 opt: 896 Z-score: 1130.8 bits: 216.2 E(85289): 3e-56
Smith-Waterman score: 896; 70.5% identity (86.3% similar) in 183 aa overlap (40-222:2-184)
10 20 30 40 50 60
pF1KB5 GYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPYLLD
:.::::::::::. :::: :::::::::.:
XP_005 MGDAPDYDRSQWLNEKFKLGLDFPNLPYLID
10 20 30
70 80 90 100 110 120
pF1KB5 GKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEKLKP
: .::::::::: :::::::.:::::::::::::.:::.:: . :: .::. . :::::
XP_005 GAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEKLKP
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 QYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFSNLKAFM
.:::::: .:: .: :::: ::::.:.::::::.::.:: .:::.::::: : ::: :.
XP_005 KYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLKDFI
100 110 120 130 140 150
190 200 210 220
pF1KB5 CRFEALEKIAAYLQSDQFCKMPINNKMAQWGNKPVC
:::.::::.::..:..: :. .::: ::::
XP_005 SRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
160 170 180
225 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 12:32:55 2016 done: Sat Nov 5 12:32:56 2016
Total Scan time: 5.280 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]