FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB5349, 376 aa
  1>>>pF1KB5349 376 - 376 aa - 376 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1955+/-0.000388; mu= 17.1791+/- 0.024
 mean_var=62.3553+/-12.350, 0's: 0 Z-trim(111.2): 19  B-trim: 25 in 1/52
 Lambda= 0.162419
 statistics sampled from 19665 (19683) to 19665 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.603), E-opt: 0.2 (0.231), width:  16
 Scan time:  7.560

The best scores are:                                      opt bits E(85289)
NP_002808 (OMIM: 603481) 26S proteasome non-ATPase ( 376) 2468 587.1 2.2e-167
NP_787128 (OMIM: 603481) 26S proteasome non-ATPase ( 378) 2170 517.3 2.3e-146
XP_011518537 (OMIM: 603481) PREDICTED: 26S proteas ( 310) 1839 439.7 4.4e-123


>>NP_002808 (OMIM: 603481) 26S proteasome non-ATPase reg  (376 aa)
 initn: 2468 init1: 2468 opt: 2468  Z-score: 3126.1  bits: 587.1 E(85289): 2.2e-167
Smith-Waterman score: 2468; 99.7% identity (100.0% similar) in 376 aa overlap (1-376:1-376)

               10        20        30        40        50        60
pF1KB5 MKDVPGFLQQSQSSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLY
       ::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MKDVPGFLQQSQNSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 ENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 GCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLYAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLYAF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 NSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSA
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB5 KITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDV
              310       320       330       340       350       360

              370      
pF1KB5 KSMEMLVEHQAHDILT
       ::::::::::::::::
NP_002 KSMEMLVEHQAHDILT
              370      

>>NP_787128 (OMIM: 603481) 26S proteasome non-ATPase reg  (378 aa)
 initn: 2199 init1: 1990 opt: 2170  Z-score: 2748.7  bits: 517.3 E(85289): 2.3e-146
Smith-Waterman score: 2170; 89.9% identity (94.2% similar) in 378 aa overlap (1-376:1-378)

               10        20        30          40        50        
pF1KB5 MKDVPGFLQQSQSSGPGQPAVWHRLEELYTKKLWHQLT--LQVLDFVQDPCFAQGDGLIK
       ::::::::::::.::::::::::::::::::.. . :.  :..   ...    ... .  
NP_787 MKDVPGFLQQSQNSGPGQPAVWHRLEELYTKNFMKTLSVNLNTGKSLSSVFHFENECIDA
               10        20        30        40        50        60

       60        70        80        90       100       110        
pF1KB5 LYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAI
          .  . :  :::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 RRCSKAGGFYFRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAI
               70        80        90       100       110       120

      120       130       140       150       160       170        
pF1KB5 GALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 GALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALR
              130       140       150       160       170       180

      180       190       200       210       220       230        
pF1KB5 FLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 FLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLY
              190       200       210       220       230       240

      240       250       260       270       280       290        
pF1KB5 AFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 AFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAK
              250       260       270       280       290       300

      300       310       320       330       340       350        
pF1KB5 SAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_787 SAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCT
              310       320       330       340       350       360

      360       370      
pF1KB5 DVKSMEMLVEHQAHDILT
       ::::::::::::::::::
NP_787 DVKSMEMLVEHQAHDILT
              370        

>>XP_011518537 (OMIM: 603481) PREDICTED: 26S proteasome   (310 aa)
 initn: 1839 init1: 1839 opt: 1839  Z-score: 2330.8  bits: 439.7 E(85289): 4.4e-123
Smith-Waterman score: 1909; 82.2% identity (82.4% similar) in 376 aa overlap (1-376:1-310)

               10        20        30        40        50        60
pF1KB5 MKDVPGFLQQSQSSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLY
       ::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKDVPGFLQQSQNSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB5 ENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB5 LKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB5 GCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLYAF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLYAF
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB5 NSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSA
       :::::::::::::::::::::::::::::::::::::::                     
XP_011 NSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLME---------------------
              250       260       270                              

              310       320       330       340       350       360
pF1KB5 KITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDV
                                                    :::::::::::::::
XP_011 ---------------------------------------------IKGMKDRLEFWCTDV
                                                  280       290    

              370      
pF1KB5 KSMEMLVEHQAHDILT
       ::::::::::::::::
XP_011 KSMEMLVEHQAHDILT
          300       310




376 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 12:29:23 2016 done: Sat Nov  5 12:29:24 2016
 Total Scan time:  7.560 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]