FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB5273, 132 aa 1>>>pF1KB5273 132 - 132 aa - 132 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1410+/-0.000412; mu= 11.2735+/- 0.025 mean_var=55.8810+/-11.042, 0's: 0 Z-trim(110.0): 29 B-trim: 0 in 0/52 Lambda= 0.171570 statistics sampled from 18232 (18260) to 18232 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.599), E-opt: 0.2 (0.214), width: 16 Scan time: 4.630 The best scores are: opt bits E(85289) NP_002668 (OMIM: 170715) myelin P2 protein [Homo s ( 132) 838 215.6 1.9e-56 NP_001433 (OMIM: 600434) fatty acid-binding protei ( 132) 587 153.4 9.6e-38 NP_004093 (OMIM: 134651) fatty acid-binding protei ( 133) 559 146.5 1.2e-35 XP_011539309 (OMIM: 134651) PREDICTED: fatty acid- ( 126) 525 138.1 3.8e-33 NP_001437 (OMIM: 602965) fatty acid-binding protei ( 132) 512 134.9 3.7e-32 NP_001435 (OMIM: 605168) fatty acid-binding protei ( 135) 499 131.7 3.5e-31 NP_001305968 (OMIM: 602965) fatty acid-binding pro ( 166) 488 129.0 2.8e-30 NP_001307925 (OMIM: 134651) fatty acid-binding pro ( 144) 432 115.1 3.7e-26 NP_001305971 (OMIM: 602965) fatty acid-binding pro ( 128) 407 108.9 2.4e-24 NP_001305970 (OMIM: 602965) fatty acid-binding pro ( 97) 374 100.7 5.4e-22 NP_004369 (OMIM: 180230) cellular retinoic acid-bi ( 137) 315 86.1 1.8e-17 NP_001869 (OMIM: 180231) cellular retinoic acid-bi ( 138) 309 84.6 5.2e-17 NP_001186652 (OMIM: 180231) cellular retinoic acid ( 138) 309 84.6 5.2e-17 XP_016855832 (OMIM: 180231) PREDICTED: cellular re ( 138) 309 84.6 5.2e-17 NP_002890 (OMIM: 180260) retinol-binding protein 1 ( 197) 305 83.7 1.4e-16 NP_443192 (OMIM: 608604) retinoid-binding protein ( 134) 301 82.6 2e-16 NP_004155 (OMIM: 180280) retinol-binding protein 2 ( 134) 268 74.5 5.7e-14 NP_113679 (OMIM: 611866) retinol-binding protein 5 ( 135) 265 73.7 9.6e-14 NP_001124465 (OMIM: 180260) retinol-binding protei ( 153) 245 68.8 3.3e-12 NP_000125 (OMIM: 134640) fatty acid-binding protei ( 132) 243 68.3 4.1e-12 NP_001124464 (OMIM: 180260) retinol-binding protei ( 157) 243 68.3 4.8e-12 XP_016875491 (OMIM: 611866) PREDICTED: retinol-bin ( 126) 198 57.1 8.9e-09 NP_001316383 (OMIM: 611866) retinol-binding protei ( 86) 150 45.2 2.4e-05 NP_001434 (OMIM: 134650) fatty acid-binding protei ( 127) 133 41.1 0.00063 >>NP_002668 (OMIM: 170715) myelin P2 protein [Homo sapie (132 aa) initn: 838 init1: 838 opt: 838 Z-score: 1134.4 bits: 215.6 E(85289): 1.9e-56 Smith-Waterman score: 838; 100.0% identity (100.0% similar) in 132 aa overlap (1-132:1-132) 10 20 30 40 50 60 pF1KB5 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKM 70 80 90 100 110 120 130 pF1KB5 KGVVCTRIYEKV :::::::::::: NP_002 KGVVCTRIYEKV 130 >>NP_001433 (OMIM: 600434) fatty acid-binding protein, a (132 aa) initn: 585 init1: 571 opt: 587 Z-score: 798.6 bits: 153.4 E(85289): 9.6e-38 Smith-Waterman score: 587; 67.2% identity (88.5% similar) in 131 aa overlap (1-131:1-131) 10 20 30 40 50 60 pF1KB5 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKN : . :.:::::::::::::::: .:::.::::....:::..::: .::.:::..:::::: NP_001 MCDAFVGTWKLVSSENFDDYMKEVGVGFATRKVAGMAKPNMIISVNGDVITIKSESTFKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKM ::::: :::::.:.:::.::.:: .::. : : .::.:::: :::::: . :.:.:: : NP_001 TEISFILGQEFDEVTADDRKVKSTITLDGGVLVHVQKWDGKSTTIKRKREDDKLVVECVM 70 80 90 100 110 120 130 pF1KB5 KGVVCTRIYEKV :::. ::.::. NP_001 KGVTSTRVYERA 130 >>NP_004093 (OMIM: 134651) fatty acid-binding protein, h (133 aa) initn: 559 init1: 559 opt: 559 Z-score: 761.1 bits: 146.5 E(85289): 1.2e-35 Smith-Waterman score: 559; 63.4% identity (88.5% similar) in 131 aa overlap (1-131:1-131) 10 20 30 40 50 60 pF1KB5 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKN : . ::::::::.:.:::::::.::::.:::......:::.:: :.:::.:..:.::::: NP_004 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKM :::::::: ::.:::::.::.::::::. :.: ..:.:::.:::. :.:..::.. NP_004 TEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILTLTH 70 80 90 100 110 120 130 pF1KB5 KGVVCTRIYEKV .:::: ::: NP_004 GTAVCTRTYEKEA 130 >>XP_011539309 (OMIM: 134651) PREDICTED: fatty acid-bind (126 aa) initn: 515 init1: 515 opt: 525 Z-score: 716.0 bits: 138.1 E(85289): 3.8e-33 Smith-Waterman score: 525; 63.6% identity (91.7% similar) in 121 aa overlap (1-121:1-121) 10 20 30 40 50 60 pF1KB5 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKN : . ::::::::.:.:::::::.::::.:::......:::.:: :.:::.:..:.::::: XP_011 MVDAFLGTWKLVDSKNFDDYMKSLGVGFATRQVASMTKPTTIIEKNGDILTLKTHSTFKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKM :::::::: ::.:::::.::.::::::. :.: ..:.:::.:::. :.:..::.. :. XP_011 TEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVRELIDGKLILMEKL 70 80 90 100 110 120 130 pF1KB5 KGVVCTRIYEKV . XP_011 QLRNVK >>NP_001437 (OMIM: 602965) fatty acid-binding protein, b (132 aa) initn: 512 init1: 512 opt: 512 Z-score: 698.3 bits: 134.9 E(85289): 3.7e-32 Smith-Waterman score: 512; 59.5% identity (85.5% similar) in 131 aa overlap (1-131:1-131) 10 20 30 40 50 60 pF1KB5 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKN : . : .::::..:.:::.::::::::.:::..::..:::::::..:: ..::: ::::: NP_001 MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKM :::::.::.::.:::::.:. ::.:.:. .: ..:.::::::.. :.. .:::: . NP_001 TEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTLTF 70 80 90 100 110 120 130 pF1KB5 KGVVCTRIYEKV :: .: ::: NP_001 GDVVAVRHYEKA 130 >>NP_001435 (OMIM: 605168) fatty acid-binding protein, e (135 aa) initn: 499 init1: 499 opt: 499 Z-score: 680.7 bits: 131.7 E(85289): 3.5e-31 Smith-Waterman score: 499; 58.7% identity (84.1% similar) in 126 aa overlap (7-132:9-134) 10 20 30 40 50 pF1KB5 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTF : :.::.:..::.::: ::::.: ::.: .::: ::. : .::.::::. NP_001 MATVQQLEGRWRLVDSKGFDEYMKELGVGIALRKMGAMAKPDCIITCDGKNLTIKTESTL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB5 KNTEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAEC :.:..: ::..:::::::.:::... .. :.: : :.:::::.:: ::: .::.:.:: NP_001 KTTQFSCTLGEKFEETTADGRKTQTVCNFTDGALVQHQEWDGKESTITRKLKDGKLVVEC 70 80 90 100 110 120 120 130 pF1KB5 KMKGVVCTRIYEKV :..:.:::::::: NP_001 VMNNVTCTRIYEKVE 130 >>NP_001305968 (OMIM: 602965) fatty acid-binding protein (166 aa) initn: 488 init1: 488 opt: 488 Z-score: 664.6 bits: 129.0 E(85289): 2.8e-30 Smith-Waterman score: 488; 62.6% identity (90.4% similar) in 115 aa overlap (1-115:1-115) 10 20 30 40 50 60 pF1KB5 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKN : . : .::::..:.:::.::::::::.:::..::..:::::::..:: ..::: ::::: NP_001 MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKM :::::.::.::.:::::.:. ::.:.:. .: ..:.::::::.. :.. .:::: NP_001 TEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMVSND 70 80 90 100 110 120 130 pF1KB5 KGVVCTRIYEKV NP_001 NSPFFLVFFSSPHTSHLLPSSSLLLPFFLLPSFFNNTSLARFFNYM 130 140 150 160 >>NP_001307925 (OMIM: 134651) fatty acid-binding protein (144 aa) initn: 432 init1: 432 opt: 432 Z-score: 590.7 bits: 115.1 E(85289): 3.7e-26 Smith-Waterman score: 527; 58.5% identity (81.7% similar) in 142 aa overlap (1-131:1-142) 10 20 30 40 pF1KB5 MSNKFLGTWKLVSSENFDDYMKAL-----------GVGLATRKLGNLAKPTVIISKKGDI : . ::::::::.:.:::::::.: :::.:::......:::.:: :.::: NP_001 MVDAFLGTWKLVDSKNFDDYMKSLAHILITFPLPSGVGFATRQVASMTKPTTIIEKNGDI 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB5 ITIRTESTFKNTEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKL .:..:.::::::::::::: ::.:::::.::.::::::. :.: ..:.:::.:::. :.: NP_001 LTLKTHSTFKNTEISFKLGVEFDETTADDRKVKSIVTLDGGKLVHLQKWDGQETTLVREL 70 80 90 100 110 120 110 120 130 pF1KB5 VNGKMVAECKMKGVVCTRIYEKV ..::.. .:::: ::: NP_001 IDGKLILTLTHGTAVCTRTYEKEA 130 140 >>NP_001305971 (OMIM: 602965) fatty acid-binding protein (128 aa) initn: 407 init1: 407 opt: 407 Z-score: 558.0 bits: 108.9 E(85289): 2.4e-24 Smith-Waterman score: 407; 58.9% identity (85.0% similar) in 107 aa overlap (25-131:21-127) 10 20 30 40 50 60 pF1KB5 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKN :::.:::..::..:::::::..:: ..::: ::::: NP_001 MQLKEKDWRSALIKTANQQKGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKN 10 20 30 40 50 70 80 90 100 110 120 pF1KB5 TEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKM :::::.::.::.:::::.:. ::.:.:. .: ..:.::::::.. :.. .:::: . NP_001 TEISFQLGEEFDETTADDRNCKSVVSLDGDKLVHIQKWDGKETNFVREIKDGKMVMTLTF 60 70 80 90 100 110 130 pF1KB5 KGVVCTRIYEKV :: .: ::: NP_001 GDVVAVRHYEKA 120 >>NP_001305970 (OMIM: 602965) fatty acid-binding protein (97 aa) initn: 382 init1: 364 opt: 374 Z-score: 515.8 bits: 100.7 E(85289): 5.4e-22 Smith-Waterman score: 374; 68.3% identity (92.7% similar) in 82 aa overlap (1-82:1-82) 10 20 30 40 50 60 pF1KB5 MSNKFLGTWKLVSSENFDDYMKALGVGLATRKLGNLAKPTVIISKKGDIITIRTESTFKN : . : .::::..:.:::.::::::::.:::..::..:::::::..:: ..::: ::::: NP_001 MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKN 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB5 TEISFKLGQEFEETTADNRKTKSIVTLQRGSLNQVQRWDGKETTIKRKLVNGKMVAECKM :::::.::.::.:::::.:. : NP_001 TEISFQLGEEFDETTADDRNCKVRNCFFFRVGMGRGE 70 80 90 132 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 12:23:01 2016 done: Sat Nov 5 12:23:02 2016 Total Scan time: 4.630 Total Display time: -0.040 Function used was FASTA [36.3.4 Apr, 2011]