Result of FASTA (omim) for
pF1KB5178
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5178, 485 aa
1>>>pF1KB5178 485 - 485 aa - 485 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3148+/-0.000414; mu= 18.2874+/- 0.026
mean_var=75.7417+/-15.820, 0's: 0 Z-trim(110.0): 101 B-trim: 0 in 0/57
Lambda= 0.147369
statistics sampled from 18127 (18244) to 18127 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.575), E-opt: 0.2 (0.214), width: 16
Scan time: 9.550
The best scores are: opt bits E(85289)
NP_000020 (OMIM: 106150,145500,267430) angiotensin ( 485) 3162 682.3 8.2e-196
NP_001747 (OMIM: 122500,611489) corticosteroid-bin ( 405) 331 80.3 1.1e-14
NP_006211 (OMIM: 107410) putative alpha-1-antitryp ( 421) 318 77.6 7.7e-14
NP_001121177 (OMIM: 107400,606963,613490) alpha-1- ( 418) 304 74.6 6e-13
NP_001002235 (OMIM: 107400,606963,613490) alpha-1- ( 418) 304 74.6 6e-13
XP_016876859 (OMIM: 107400,606963,613490) PREDICTE ( 418) 304 74.6 6e-13
NP_001121179 (OMIM: 107400,606963,613490) alpha-1- ( 418) 304 74.6 6e-13
NP_001121172 (OMIM: 107400,606963,613490) alpha-1- ( 418) 304 74.6 6e-13
NP_001121175 (OMIM: 107400,606963,613490) alpha-1- ( 418) 304 74.6 6e-13
NP_001002236 (OMIM: 107400,606963,613490) alpha-1- ( 418) 304 74.6 6e-13
NP_001121173 (OMIM: 107400,606963,613490) alpha-1- ( 418) 304 74.6 6e-13
NP_000286 (OMIM: 107400,606963,613490) alpha-1-ant ( 418) 304 74.6 6e-13
NP_001121178 (OMIM: 107400,606963,613490) alpha-1- ( 418) 304 74.6 6e-13
NP_001121174 (OMIM: 107400,606963,613490) alpha-1- ( 418) 304 74.6 6e-13
NP_001121176 (OMIM: 107400,606963,613490) alpha-1- ( 418) 304 74.6 6e-13
XP_016876842 (OMIM: 605271) PREDICTED: protein Z-d ( 484) 287 71.0 8.2e-12
XP_005267790 (OMIM: 605271) PREDICTED: protein Z-d ( 444) 286 70.8 8.9e-12
NP_001094077 (OMIM: 605271) protein Z-dependent pr ( 444) 286 70.8 8.9e-12
NP_057270 (OMIM: 605271) protein Z-dependent prote ( 444) 286 70.8 8.9e-12
NP_001226 (OMIM: 600943,610504,613848) serpin H1 p ( 418) 273 68.0 5.8e-11
NP_001193943 (OMIM: 600943,610504,613848) serpin H ( 418) 273 68.0 5.8e-11
XP_011543629 (OMIM: 600943,610504,613848) PREDICTE ( 418) 273 68.0 5.8e-11
NP_000615 (OMIM: 601841) plasma serine protease in ( 406) 271 67.6 7.6e-11
NP_006208 (OMIM: 605587) serpin I2 isoform 2 precu ( 405) 261 65.5 3.3e-10
NP_001012303 (OMIM: 605587) serpin I2 isoform 1 pr ( 415) 261 65.5 3.4e-10
NP_000176 (OMIM: 142360,612356) heparin cofactor 2 ( 499) 252 63.6 1.5e-09
NP_008850 (OMIM: 600517) serpin B3 [Homo sapiens] ( 390) 236 60.1 1.3e-08
NP_001159393 (OMIM: 262850,613168) alpha-2-antipla ( 427) 230 58.9 3.3e-08
NP_000345 (OMIM: 300932,314200) thyroxine-binding ( 415) 222 57.2 1.1e-07
NP_001271204 (OMIM: 615677) serpin A9 isoform C [H ( 399) 215 55.7 2.9e-07
XP_011535016 (OMIM: 615677) PREDICTED: serpin A9 i ( 417) 215 55.7 3e-07
XP_011535017 (OMIM: 615677) PREDICTED: serpin A9 i ( 417) 215 55.7 3e-07
NP_783866 (OMIM: 615677) serpin A9 isoform A [Homo ( 435) 215 55.7 3.1e-07
NP_002606 (OMIM: 172860,613982) pigment epithelium ( 418) 211 54.8 5.4e-07
NP_001316832 (OMIM: 172860,613982) pigment epithel ( 418) 211 54.8 5.4e-07
NP_001271205 (OMIM: 615677) serpin A9 isoform D [H ( 286) 202 52.8 1.5e-06
NP_001035983 (OMIM: 615677) serpin A9 isoform B [H ( 335) 202 52.9 1.7e-06
XP_011535018 (OMIM: 615677) PREDICTED: serpin A9 i ( 337) 202 52.9 1.7e-06
XP_011535019 (OMIM: 615677) PREDICTED: serpin A9 i ( 337) 202 52.9 1.7e-06
NP_001316834 (OMIM: 172860,613982) pigment epithel ( 231) 199 52.1 2e-06
NP_001316833 (OMIM: 172860,613982) pigment epithel ( 231) 199 52.1 2e-06
NP_001027466 (OMIM: 106100,120790,606860) plasma p ( 500) 202 53.0 2.3e-06
NP_000053 (OMIM: 106100,120790,606860) plasma prot ( 500) 202 53.0 2.3e-06
NP_001076 (OMIM: 107280) alpha-1-antichymotrypsin ( 423) 187 49.7 1.9e-05
NP_005016 (OMIM: 602445,604218) neuroserpin precur ( 410) 177 47.6 7.9e-05
XP_016862107 (OMIM: 602445,604218) PREDICTED: neur ( 410) 177 47.6 7.9e-05
NP_001116224 (OMIM: 602445,604218) neuroserpin pre ( 410) 177 47.6 7.9e-05
NP_002631 (OMIM: 601697,617115) serpin B8 isoform ( 374) 175 47.2 9.9e-05
NP_942130 (OMIM: 601697,617115) serpin B8 isoform ( 374) 175 47.2 9.9e-05
NP_778206 (OMIM: 600518) serpin B4 isoform 2 [Homo ( 369) 171 46.3 0.00018
>>NP_000020 (OMIM: 106150,145500,267430) angiotensinogen (485 aa)
initn: 3162 init1: 3162 opt: 3162 Z-score: 3636.5 bits: 682.3 E(85289): 8.2e-196
Smith-Waterman score: 3162; 99.8% identity (99.8% similar) in 485 aa overlap (1-485:1-485)
10 20 30 40 50 60
pF1KB5 MRKRAPQSEMAPAGVSLRATILCLLAWAGLAAGDRVYIHPFHLVIHNESTCEQLAKANAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MRKRAPQSEMAPAGVSLRATILCLLAWAGLAAGDRVYIHPFHLVIHNESTCEQLAKANAG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 KPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDTEDKLRAAMVGMLANFLGFRIYGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KPKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDTEDKLRAAMVGMLANFLGFRIYGM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 HSELWGVVHGATVLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAHKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HSELWGVVHGATVLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAHKV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 LSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLALYTPVVLPRSLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLALYTPVVLPRSLD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 FTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNTYVHFQGKMKGFSLLAEPQEF
::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::
NP_000 FTELDVAAEKIDRFMQAVTGWKTGCSLMGASVDSTLAFNTYVHFQGKMKGFSLLAEPQEF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 WVDNSTSVSVPMLSGMGTFQHWSDIQDNFSVTQVPFTESACLLLIQPHYASDLDKVEGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 WVDNSTSVSVPMLSGMGTFQHWSDIQDNFSVTQVPFTESACLLLIQPHYASDLDKVEGLT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 FQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDRIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 FQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDRIR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 VGEVLNSIFFELEADEREPTESTQQLNKPEVLEVTLNRPFLFAVYDQSATALHFLGRVAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VGEVLNSIFFELEADEREPTESTQQLNKPEVLEVTLNRPFLFAVYDQSATALHFLGRVAN
430 440 450 460 470 480
pF1KB5 PLSTA
:::::
NP_000 PLSTA
>>NP_001747 (OMIM: 122500,611489) corticosteroid-binding (405 aa)
initn: 149 init1: 67 opt: 331 Z-score: 384.7 bits: 80.3 E(85289): 1.1e-14
Smith-Waterman score: 331; 23.5% identity (62.0% similar) in 358 aa overlap (134-482:65-405)
110 120 130 140 150 160
pF1KB5 AMVGMLANFLGFRIYGMHSELWGVVHGATVLSPTAVFGTLASLYLGALDHTADRLQAILG
.::... .:: : ::. :: : : . :
NP_001 HHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHT--RAQLLQG
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB5 VPWKDKNCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPF
. . : : : .. .. ...: .. :.. ..:.. .. ..... : .:.: . :
NP_001 LGF---NLTERSET-EIHQGFQHLHQLFA---KSDTSLEMTMGNAL--FLDGSLELLESF
100 110 120 130 140
230 240 250 260 270 280
pF1KB5 VQGLA-LYTPVVLPRSLDFTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNTYV
. : :: ...: . .:...:. ... : : ..: . . :.. .:.
NP_001 SADIKHYYESEVL--AMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYI
150 160 170 180 190 200
290 300 310 320 330 340
pF1KB5 HFQGKM-KGFSLLAEPQE-FWVDNSTSVSVPMLSGMGTFQHWSDIQDNFSVTQVPFTESA
:.: . :.: . .: :.::..: :.:::. .:... : . ...:. .. ..
NP_001 FFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNG
210 220 230 240 250 260
350 360 370 380 390
pF1KB5 CLLLIQPHYASDLDKVEGLTFQQNSLN-WMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQA
...: : .. . .:. ....: : :. . : .:.....: ::: :.: .
NP_001 TVFFILPDKGKMNTVIAALS--RDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEM
270 280 290 300 310
400 410 420 430 440 450
pF1KB5 ELPAILHTELNLQKLSND-RIRVGEVLNSIFFELEADEREPTESTQ-QLN---KPEVLEV
. .. .. :......: ... ..:... ..:. . . . :: :: :: .:.
NP_001 GIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILR-
320 330 340 350 360 370
460 470 480
pF1KB5 TLNRPFLFAVYDQSATALHFLGRVANPLSTA
.:.::.. ..:. . . ::.:: ::.
NP_001 -FNQPFIIMIFDHFTWSSLFLARVMNPV
380 390 400
>>NP_006211 (OMIM: 107410) putative alpha-1-antitrypsin- (421 aa)
initn: 171 init1: 80 opt: 318 Z-score: 369.5 bits: 77.6 E(85289): 7.7e-14
Smith-Waterman score: 318; 25.8% identity (57.5% similar) in 372 aa overlap (118-481:62-418)
90 100 110 120 130 140
pF1KB5 LVLVAAKLDTEDKLRAAMVGMLANFLGFRIYGMHSELWGVVHGATVL-SPTAVFGTLASL
. ...:: . . ..:: .::.: ..: :
NP_006 AQKTDTSHHDQGDWEDLACQKISYNVTDLAFDLYKELADLSQTSNVLVTPTSVAMAFAML
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB5 YLGALDHTADRLQAILGVPWKDKNCTSRLDAHKVLSALQAVQGLLVAQGRADSQAQLLLS
::. : : . . :. . : : .: :. .: : : : .: :.. :: .
NP_006 SLGTKADT--RTEILEGL---NVNLTETPEA-KIHECFQQV---LQALSRPDTRLQL--T
100 110 120 130 140
210 220 230 240 250 260
pF1KB5 TVVGVFTAPGLHLKQPFVQGLA-LYTPVVLPRSLDFTELDVAAEKIDRFMQAVTGWKTGC
: ..:. ...: . :.. :: . :..: . . : :.:. ... :: :.
NP_006 TGSSLFVNKSMKLVDTFLEDTKKLYHSEA--SSINFRDTEEAKEQINNYVEKRTGRKVVD
150 160 170 180 190
270 280 290 300 310 320
pF1KB5 SLTGASVDSTLAFNTYVHFQGKMKGFSLLAEP---QEFWVDNSTSVSVPMLSGMGTFQHW
. . :..::. :. :.:: : .. :: . : ::..: . :::.. .: :.
NP_006 LVKHLKKDTSLALVDYISFHGKWKD-KFKAEHIMVEGFHVDDKTIIRVPMINHLGRFDIH
200 210 220 230 240 250
330 340 350 360 370 380
pF1KB5 SDIQDNFSVTQVPFTESACLLLIQPHYASDLDKVEGLTFQQNSLNWMKKLSPRTIHLTMP
: . . : .. .: ..: : . . : ::... : .. .. :.:.: .:
NP_006 RDRELSSWVLAQHYVGNATAFFILPDPKKMWQLEEKLTYSHLE-NIQRAFDIRSINLHFP
260 270 280 290 300 310
390 400 410 420 430 440
pF1KB5 QLVLQGSYDLQDLLAQAELPAILHTELNLQKLSNDR-IRVGEVLNSIFFELEADEREPTE
.: ..:.: :. .: . . :. .: .:. .:.. ........ . .. : :
NP_006 KLSISGTYKLKRVLRNLGITKIFSNEADLSGVSQEAPLKLSKAVHVAVLTIDEKGTEATG
320 330 340 350 360 370
450 460 470 480
pF1KB5 STQQLNKP--EVLEVTLNRPFLFAVYDQSATALHFLGRVANPLSTA
. . .: . : .::::: . :. .. :.:.:.::
NP_006 APHLEEKAWSKYQTVMFNRPFLVIIKDDITNFPLFIGKVVNPTQK
380 390 400 410 420
>>NP_001121177 (OMIM: 107400,606963,613490) alpha-1-anti (418 aa)
initn: 168 init1: 93 opt: 304 Z-score: 353.5 bits: 74.6 E(85289): 6e-13
Smith-Waterman score: 304; 22.9% identity (59.1% similar) in 401 aa overlap (92-481:32-415)
70 80 90 100 110
pF1KB5 PKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDT--EDKLRAAMVGMLANFLGFRIYG
: : :: .:. . .. . :. : ..
NP_001 PSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEF-AFS
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB5 MHSELWGVVHGATVL-SPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAH
.. .: ...... ::... ..: : ::. : :.. . :. . : : .:.
NP_001 LYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI--LEGLNF---NLTEIPEAQ
70 80 90 100 110
180 190 200 210 220 230
pF1KB5 KVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLA-LYTPVVLPR
.. : :: . .. ::: :: .: :.: . ::.: . :.. . :: ..
NP_001 ----IHEGFQELLRTLNQPDSQLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHSEAF--
120 130 140 150 160
240 250 260 270 280 290
pF1KB5 SLDFTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNTYVHFQGKM-KGFSLL-A
...: . . : ..:. ... : : . . :...:. .:. :.:: . : . .
NP_001 TVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDT
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 EPQEFWVDNSTSVSVPMLSGMGTF--QHWSDIQDNFSVTQVPFTESACLLLIQPHYASDL
: ..: ::. :.:.:::.. .: : :: . ... : . . .: ... : . :
NP_001 EEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW--VLLMKYLGNATAIFFLPD-EGKL
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 DKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQK
...:. .. ..... . :. : .:.: . :.:::...:.: . .. . .:.
NP_001 QHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSG
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB5 LSNDR-IRVGEVLNSIFFELEADEREPTESTQQLNKPEVL--EVTLNRPFLFAVYDQSAT
.... ......... . .. : . . : . :: .:.::.: . .:..
NP_001 VTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTK
350 360 370 380 390 400
480
pF1KB5 ALHFLGRVANPLSTA
. :.:.:.::
NP_001 SPLFMGKVVNPTQK
410
>>NP_001002235 (OMIM: 107400,606963,613490) alpha-1-anti (418 aa)
initn: 168 init1: 93 opt: 304 Z-score: 353.5 bits: 74.6 E(85289): 6e-13
Smith-Waterman score: 304; 22.9% identity (59.1% similar) in 401 aa overlap (92-481:32-415)
70 80 90 100 110
pF1KB5 PKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDT--EDKLRAAMVGMLANFLGFRIYG
: : :: .:. . .. . :. : ..
NP_001 PSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEF-AFS
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB5 MHSELWGVVHGATVL-SPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAH
.. .: ...... ::... ..: : ::. : :.. . :. . : : .:.
NP_001 LYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI--LEGLNF---NLTEIPEAQ
70 80 90 100 110
180 190 200 210 220 230
pF1KB5 KVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLA-LYTPVVLPR
.. : :: . .. ::: :: .: :.: . ::.: . :.. . :: ..
NP_001 ----IHEGFQELLRTLNQPDSQLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHSEAF--
120 130 140 150 160
240 250 260 270 280 290
pF1KB5 SLDFTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNTYVHFQGKM-KGFSLL-A
...: . . : ..:. ... : : . . :...:. .:. :.:: . : . .
NP_001 TVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDT
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 EPQEFWVDNSTSVSVPMLSGMGTF--QHWSDIQDNFSVTQVPFTESACLLLIQPHYASDL
: ..: ::. :.:.:::.. .: : :: . ... : . . .: ... : . :
NP_001 EEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW--VLLMKYLGNATAIFFLPD-EGKL
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 DKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQK
...:. .. ..... . :. : .:.: . :.:::...:.: . .. . .:.
NP_001 QHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSG
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB5 LSNDR-IRVGEVLNSIFFELEADEREPTESTQQLNKPEVL--EVTLNRPFLFAVYDQSAT
.... ......... . .. : . . : . :: .:.::.: . .:..
NP_001 VTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTK
350 360 370 380 390 400
480
pF1KB5 ALHFLGRVANPLSTA
. :.:.:.::
NP_001 SPLFMGKVVNPTQK
410
>>XP_016876859 (OMIM: 107400,606963,613490) PREDICTED: a (418 aa)
initn: 168 init1: 93 opt: 304 Z-score: 353.5 bits: 74.6 E(85289): 6e-13
Smith-Waterman score: 304; 22.9% identity (59.1% similar) in 401 aa overlap (92-481:32-415)
70 80 90 100 110
pF1KB5 PKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDT--EDKLRAAMVGMLANFLGFRIYG
: : :: .:. . .. . :. : ..
XP_016 PSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEF-AFS
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB5 MHSELWGVVHGATVL-SPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAH
.. .: ...... ::... ..: : ::. : :.. . :. . : : .:.
XP_016 LYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI--LEGLNF---NLTEIPEAQ
70 80 90 100 110
180 190 200 210 220 230
pF1KB5 KVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLA-LYTPVVLPR
.. : :: . .. ::: :: .: :.: . ::.: . :.. . :: ..
XP_016 ----IHEGFQELLRTLNQPDSQLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHSEAF--
120 130 140 150 160
240 250 260 270 280 290
pF1KB5 SLDFTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNTYVHFQGKM-KGFSLL-A
...: . . : ..:. ... : : . . :...:. .:. :.:: . : . .
XP_016 TVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDT
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 EPQEFWVDNSTSVSVPMLSGMGTF--QHWSDIQDNFSVTQVPFTESACLLLIQPHYASDL
: ..: ::. :.:.:::.. .: : :: . ... : . . .: ... : . :
XP_016 EEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW--VLLMKYLGNATAIFFLPD-EGKL
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 DKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQK
...:. .. ..... . :. : .:.: . :.:::...:.: . .. . .:.
XP_016 QHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSG
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB5 LSNDR-IRVGEVLNSIFFELEADEREPTESTQQLNKPEVL--EVTLNRPFLFAVYDQSAT
.... ......... . .. : . . : . :: .:.::.: . .:..
XP_016 VTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTK
350 360 370 380 390 400
480
pF1KB5 ALHFLGRVANPLSTA
. :.:.:.::
XP_016 SPLFMGKVVNPTQK
410
>>NP_001121179 (OMIM: 107400,606963,613490) alpha-1-anti (418 aa)
initn: 168 init1: 93 opt: 304 Z-score: 353.5 bits: 74.6 E(85289): 6e-13
Smith-Waterman score: 304; 22.9% identity (59.1% similar) in 401 aa overlap (92-481:32-415)
70 80 90 100 110
pF1KB5 PKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDT--EDKLRAAMVGMLANFLGFRIYG
: : :: .:. . .. . :. : ..
NP_001 PSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEF-AFS
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB5 MHSELWGVVHGATVL-SPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAH
.. .: ...... ::... ..: : ::. : :.. . :. . : : .:.
NP_001 LYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI--LEGLNF---NLTEIPEAQ
70 80 90 100 110
180 190 200 210 220 230
pF1KB5 KVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLA-LYTPVVLPR
.. : :: . .. ::: :: .: :.: . ::.: . :.. . :: ..
NP_001 ----IHEGFQELLRTLNQPDSQLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHSEAF--
120 130 140 150 160
240 250 260 270 280 290
pF1KB5 SLDFTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNTYVHFQGKM-KGFSLL-A
...: . . : ..:. ... : : . . :...:. .:. :.:: . : . .
NP_001 TVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDT
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 EPQEFWVDNSTSVSVPMLSGMGTF--QHWSDIQDNFSVTQVPFTESACLLLIQPHYASDL
: ..: ::. :.:.:::.. .: : :: . ... : . . .: ... : . :
NP_001 EEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW--VLLMKYLGNATAIFFLPD-EGKL
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 DKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQK
...:. .. ..... . :. : .:.: . :.:::...:.: . .. . .:.
NP_001 QHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSG
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB5 LSNDR-IRVGEVLNSIFFELEADEREPTESTQQLNKPEVL--EVTLNRPFLFAVYDQSAT
.... ......... . .. : . . : . :: .:.::.: . .:..
NP_001 VTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTK
350 360 370 380 390 400
480
pF1KB5 ALHFLGRVANPLSTA
. :.:.:.::
NP_001 SPLFMGKVVNPTQK
410
>>NP_001121172 (OMIM: 107400,606963,613490) alpha-1-anti (418 aa)
initn: 168 init1: 93 opt: 304 Z-score: 353.5 bits: 74.6 E(85289): 6e-13
Smith-Waterman score: 304; 22.9% identity (59.1% similar) in 401 aa overlap (92-481:32-415)
70 80 90 100 110
pF1KB5 PKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDT--EDKLRAAMVGMLANFLGFRIYG
: : :: .:. . .. . :. : ..
NP_001 PSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEF-AFS
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB5 MHSELWGVVHGATVL-SPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAH
.. .: ...... ::... ..: : ::. : :.. . :. . : : .:.
NP_001 LYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI--LEGLNF---NLTEIPEAQ
70 80 90 100 110
180 190 200 210 220 230
pF1KB5 KVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLA-LYTPVVLPR
.. : :: . .. ::: :: .: :.: . ::.: . :.. . :: ..
NP_001 ----IHEGFQELLRTLNQPDSQLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHSEAF--
120 130 140 150 160
240 250 260 270 280 290
pF1KB5 SLDFTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNTYVHFQGKM-KGFSLL-A
...: . . : ..:. ... : : . . :...:. .:. :.:: . : . .
NP_001 TVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDT
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 EPQEFWVDNSTSVSVPMLSGMGTF--QHWSDIQDNFSVTQVPFTESACLLLIQPHYASDL
: ..: ::. :.:.:::.. .: : :: . ... : . . .: ... : . :
NP_001 EEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW--VLLMKYLGNATAIFFLPD-EGKL
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 DKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQK
...:. .. ..... . :. : .:.: . :.:::...:.: . .. . .:.
NP_001 QHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSG
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB5 LSNDR-IRVGEVLNSIFFELEADEREPTESTQQLNKPEVL--EVTLNRPFLFAVYDQSAT
.... ......... . .. : . . : . :: .:.::.: . .:..
NP_001 VTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTK
350 360 370 380 390 400
480
pF1KB5 ALHFLGRVANPLSTA
. :.:.:.::
NP_001 SPLFMGKVVNPTQK
410
>>NP_001121175 (OMIM: 107400,606963,613490) alpha-1-anti (418 aa)
initn: 168 init1: 93 opt: 304 Z-score: 353.5 bits: 74.6 E(85289): 6e-13
Smith-Waterman score: 304; 22.9% identity (59.1% similar) in 401 aa overlap (92-481:32-415)
70 80 90 100 110
pF1KB5 PKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDT--EDKLRAAMVGMLANFLGFRIYG
: : :: .:. . .. . :. : ..
NP_001 PSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEF-AFS
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB5 MHSELWGVVHGATVL-SPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAH
.. .: ...... ::... ..: : ::. : :.. . :. . : : .:.
NP_001 LYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI--LEGLNF---NLTEIPEAQ
70 80 90 100 110
180 190 200 210 220 230
pF1KB5 KVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLA-LYTPVVLPR
.. : :: . .. ::: :: .: :.: . ::.: . :.. . :: ..
NP_001 ----IHEGFQELLRTLNQPDSQLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHSEAF--
120 130 140 150 160
240 250 260 270 280 290
pF1KB5 SLDFTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNTYVHFQGKM-KGFSLL-A
...: . . : ..:. ... : : . . :...:. .:. :.:: . : . .
NP_001 TVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDT
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 EPQEFWVDNSTSVSVPMLSGMGTF--QHWSDIQDNFSVTQVPFTESACLLLIQPHYASDL
: ..: ::. :.:.:::.. .: : :: . ... : . . .: ... : . :
NP_001 EEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW--VLLMKYLGNATAIFFLPD-EGKL
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 DKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQK
...:. .. ..... . :. : .:.: . :.:::...:.: . .. . .:.
NP_001 QHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSG
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB5 LSNDR-IRVGEVLNSIFFELEADEREPTESTQQLNKPEVL--EVTLNRPFLFAVYDQSAT
.... ......... . .. : . . : . :: .:.::.: . .:..
NP_001 VTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTK
350 360 370 380 390 400
480
pF1KB5 ALHFLGRVANPLSTA
. :.:.:.::
NP_001 SPLFMGKVVNPTQK
410
>>NP_001002236 (OMIM: 107400,606963,613490) alpha-1-anti (418 aa)
initn: 168 init1: 93 opt: 304 Z-score: 353.5 bits: 74.6 E(85289): 6e-13
Smith-Waterman score: 304; 22.9% identity (59.1% similar) in 401 aa overlap (92-481:32-415)
70 80 90 100 110
pF1KB5 PKDPTFIPAPIQAKTSPVDEKALQDQLVLVAAKLDT--EDKLRAAMVGMLANFLGFRIYG
: : :: .:. . .. . :. : ..
NP_001 PSSVSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEF-AFS
10 20 30 40 50 60
120 130 140 150 160 170
pF1KB5 MHSELWGVVHGATVL-SPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKNCTSRLDAH
.. .: ...... ::... ..: : ::. : :.. . :. . : : .:.
NP_001 LYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI--LEGLNF---NLTEIPEAQ
70 80 90 100 110
180 190 200 210 220 230
pF1KB5 KVLSALQAVQGLLVAQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGLA-LYTPVVLPR
.. : :: . .. ::: :: .: :.: . ::.: . :.. . :: ..
NP_001 ----IHEGFQELLRTLNQPDSQLQL--TTGNGLFLSEGLKLVDKFLEDVKKLYHSEAF--
120 130 140 150 160
240 250 260 270 280 290
pF1KB5 SLDFTELDVAAEKIDRFMQAVTGWKTGCSLTGASVDSTLAFNTYVHFQGKM-KGFSLL-A
...: . . : ..:. ... : : . . :...:. .:. :.:: . : . .
NP_001 TVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDT
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB5 EPQEFWVDNSTSVSVPMLSGMGTF--QHWSDIQDNFSVTQVPFTESACLLLIQPHYASDL
: ..: ::. :.:.:::.. .: : :: . ... : . . .: ... : . :
NP_001 EEEDFHVDQVTTVKVPMMKRLGMFNIQHCKKLSSW--VLLMKYLGNATAIFFLPD-EGKL
230 240 250 260 270 280
360 370 380 390 400 410
pF1KB5 DKVEGLTFQQNSLNWMKKLSPRTIHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQK
...:. .. ..... . :. : .:.: . :.:::...:.: . .. . .:.
NP_001 QHLENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSG
290 300 310 320 330 340
420 430 440 450 460 470
pF1KB5 LSNDR-IRVGEVLNSIFFELEADEREPTESTQQLNKPEVL--EVTLNRPFLFAVYDQSAT
.... ......... . .. : . . : . :: .:.::.: . .:..
NP_001 VTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTK
350 360 370 380 390 400
480
pF1KB5 ALHFLGRVANPLSTA
. :.:.:.::
NP_001 SPLFMGKVVNPTQK
410
485 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:23:53 2016 done: Sat Nov 5 06:23:54 2016
Total Scan time: 9.550 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]