Result of FASTA (omim) for
pF1KB5055
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5055, 514 aa
1>>>pF1KB5055 514 - 514 aa - 514 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0884+/-0.000497; mu= 19.5060+/- 0.031
mean_var=69.5131+/-14.388, 0's: 0 Z-trim(107.8): 45 B-trim: 136 in 1/48
Lambda= 0.153830
statistics sampled from 15871 (15910) to 15871 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.536), E-opt: 0.2 (0.187), width: 16
Scan time: 9.260
The best scores are: opt bits E(85289)
NP_000875 (OMIM: 146691) inosine-5'-monophosphate ( 514) 3332 749.4 5.9e-216
NP_001136045 (OMIM: 146690,180105,613837) inosine- ( 514) 2882 649.5 6.9e-186
XP_016867661 (OMIM: 146690,180105,613837) PREDICTE ( 522) 2882 649.5 7e-186
NP_899066 (OMIM: 146690,180105,613837) inosine-5'- ( 563) 2882 649.5 7.4e-186
NP_001096075 (OMIM: 146690,180105,613837) inosine- ( 589) 2882 649.5 7.6e-186
NP_000874 (OMIM: 146690,180105,613837) inosine-5'- ( 599) 2882 649.5 7.7e-186
XP_016867660 (OMIM: 146690,180105,613837) PREDICTE ( 523) 2854 643.3 5.2e-184
XP_016867658 (OMIM: 146690,180105,613837) PREDICTE ( 564) 2854 643.3 5.5e-184
XP_016867657 (OMIM: 146690,180105,613837) PREDICTE ( 590) 2854 643.3 5.7e-184
NP_001136046 (OMIM: 146690,180105,613837) inosine- ( 509) 2833 638.6 1.3e-182
NP_001291450 (OMIM: 146690,180105,613837) inosine- ( 530) 2697 608.4 1.6e-173
NP_001136048 (OMIM: 146690,180105,613837) inosine- ( 566) 2697 608.5 1.7e-173
XP_016867659 (OMIM: 146690,180105,613837) PREDICTE ( 531) 2669 602.2 1.2e-171
XP_016861839 (OMIM: 146691) PREDICTED: inosine-5'- ( 559) 2627 592.9 8e-169
NP_001136047 (OMIM: 146690,180105,613837) inosine- ( 489) 2251 509.4 9.5e-144
XP_006713191 (OMIM: 146691) PREDICTED: inosine-5'- ( 608) 2180 493.7 6.2e-139
XP_016867662 (OMIM: 146690,180105,613837) PREDICTE ( 415) 1850 420.4 5.1e-117
XP_016861838 (OMIM: 146691) PREDICTED: inosine-5'- ( 583) 1475 337.3 7.5e-92
NP_001269952 (OMIM: 610781) GMP reductase 2 isofor ( 320) 435 106.3 1.4e-22
NP_006868 (OMIM: 139265) GMP reductase 1 [Homo sap ( 345) 433 105.9 2.1e-22
XP_016876847 (OMIM: 610781) PREDICTED: GMP reducta ( 312) 429 104.9 3.5e-22
XP_016876848 (OMIM: 610781) PREDICTED: GMP reducta ( 312) 429 104.9 3.5e-22
XP_016876846 (OMIM: 610781) PREDICTED: GMP reducta ( 312) 429 104.9 3.5e-22
NP_001002000 (OMIM: 610781) GMP reductase 2 isofor ( 348) 429 105.0 3.8e-22
NP_001002002 (OMIM: 610781) GMP reductase 2 isofor ( 348) 429 105.0 3.8e-22
NP_001002001 (OMIM: 610781) GMP reductase 2 isofor ( 348) 429 105.0 3.8e-22
NP_057660 (OMIM: 610781) GMP reductase 2 isoform 1 ( 366) 429 105.0 4e-22
XP_006720228 (OMIM: 610781) PREDICTED: GMP reducta ( 373) 381 94.3 6.5e-19
XP_016876845 (OMIM: 610781) PREDICTED: GMP reducta ( 373) 381 94.3 6.5e-19
NP_001269950 (OMIM: 610781) GMP reductase 2 isofor ( 373) 381 94.3 6.5e-19
XP_005267797 (OMIM: 610781) PREDICTED: GMP reducta ( 409) 381 94.4 7e-19
XP_005267799 (OMIM: 610781) PREDICTED: GMP reducta ( 409) 381 94.4 7e-19
XP_005267798 (OMIM: 610781) PREDICTED: GMP reducta ( 409) 381 94.4 7e-19
NP_001269951 (OMIM: 610781) GMP reductase 2 isofor ( 427) 381 94.4 7.2e-19
XP_016876849 (OMIM: 610781) PREDICTED: GMP reducta ( 246) 280 71.8 2.6e-12
XP_011512810 (OMIM: 139265) PREDICTED: GMP reducta ( 316) 277 71.2 5.1e-12
>>NP_000875 (OMIM: 146691) inosine-5'-monophosphate dehy (514 aa)
initn: 3332 init1: 3332 opt: 3332 Z-score: 3998.0 bits: 749.4 E(85289): 5.9e-216
Smith-Waterman score: 3332; 100.0% identity (100.0% similar) in 514 aa overlap (1-514:1-514)
10 20 30 40 50 60
pF1KB5 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR
430 440 450 460 470 480
490 500 510
pF1KB5 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
::::::::::::::::::::::::::::::::::
NP_000 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
490 500 510
>>NP_001136045 (OMIM: 146690,180105,613837) inosine-5'-m (514 aa)
initn: 2882 init1: 2882 opt: 2882 Z-score: 3458.3 bits: 649.5 E(85289): 6.9e-186
Smith-Waterman score: 2882; 84.0% identity (95.3% similar) in 514 aa overlap (1-514:1-514)
10 20 30 40 50 60
pF1KB5 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT
::::::::::.:::.::::::::: .:::::::::::::.::: ::.::::::::.:::
NP_001 MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV
:::::.:::::::::: ::::::: ::::::::::::::::::::::::.::::::::::
NP_001 LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQGFITDPVV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT
:::. : ::.::: :::: :::::.:: :::.::::..::::::: :..: .: :.::
NP_001 LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA
: .:::::::.:::::::::::::::::::::. ::::::::::::::::::::::::.
NP_001 PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI
.::::::::.::.::::::::::.::::::.:::::::::..:: :..:::.:::.::::
NP_001 QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP
:::::::::::::::::::.:::::: :::::::::.::::::.::::::.:::::::::
NP_001 GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM
.:::::::.:::..:::::::::::::::::::::::::::::::.::::::::::::::
NP_001 IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR
.: :::.:::::.::.:.::::::..::::::.::::::::::::.::::::.::. .:
NP_001 EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR
430 440 450 460 470 480
490 500 510
pF1KB5 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
.::::::::::::: :::.:::::.::::::::.
NP_001 SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
490 500 510
>>XP_016867661 (OMIM: 146690,180105,613837) PREDICTED: i (522 aa)
initn: 2882 init1: 2882 opt: 2882 Z-score: 3458.2 bits: 649.5 E(85289): 7e-186
Smith-Waterman score: 2882; 84.0% identity (95.3% similar) in 514 aa overlap (1-514:9-522)
10 20 30 40 50
pF1KB5 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLT
::::::::::.:::.::::::::: .:::::::::::::.::: ::.::::
XP_016 MDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 SALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQ
::::.::::::::.:::::::::: ::::::: ::::::::::::::::::::::::.::
XP_016 SALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHD
:::::::::::. : ::.::: :::: :::::.:: :::.::::..::::::: :..:
XP_016 GFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 CFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRD
.: :.:: : .:::::::.:::::::::::::::::::::. :::::::::::::::::
XP_016 TLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 YPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKD
:::::::..::::::::.::.::::::::::.::::::.:::::::::..:: :..:::.
XP_016 YPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 KYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSE
:::.:::::::::::::::::::::::.:::::: :::::::::.::::::.::::::.:
XP_016 KYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 YARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYR
::::::::.:::::::.:::..:::::::::::::::::::::::::::::::.::::::
XP_016 YARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 GMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIG
::::::::.: :::.:::::.::.:.::::::..::::::.::::::::::::.:::::
XP_016 GMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIG
430 440 450 460 470 480
480 490 500 510
pF1KB5 AKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
:.::. .:.::::::::::::: :::.:::::.::::::::.
XP_016 ARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
490 500 510 520
>>NP_899066 (OMIM: 146690,180105,613837) inosine-5'-mono (563 aa)
initn: 2909 init1: 2882 opt: 2882 Z-score: 3457.7 bits: 649.5 E(85289): 7.4e-186
Smith-Waterman score: 2882; 84.0% identity (95.3% similar) in 514 aa overlap (1-514:50-563)
10 20 30
pF1KB5 MADYLISGGTSYVPDDGLTAQQLFNCGDGL
::::::::::.:::.::::::::: .:::
NP_899 EPGARQHPGHETAAQRYSARLLQAGYEPESMADYLISGGTGYVPEDGLTAQQLFASADGL
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB5 TYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGF
::::::::::.::: ::.::::::::.::::::::.:::::::::: ::::::: :::::
NP_899 TYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGF
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB5 IHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRM
:::::::::::::::::::.:::::::::::::. : ::.::: :::: :::::.:: :
NP_899 IHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTM
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB5 GSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLP
::.::::..::::::: :..: .: :.:: : .:::::::.::::::::::::::::::
NP_899 GSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLP
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB5 IVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDV
:::. ::::::::::::::::::::::::..::::::::.::.::::::::::.::::::
NP_899 IVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDV
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB5 VVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSI
.:::::::::..:: :..:::.:::.:::::::::::::::::::::::.:::::: :::
NP_899 IVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSI
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB5 CITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLL
::::::.::::::.::::::.:::::::::.:::::::.:::..::::::::::::::::
NP_899 CITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLL
380 390 400 410 420 430
400 410 420 430 440 450
pF1KB5 AATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDK
:::::::::::::::.::::::::::::::.: :::.:::::.::.:.::::::..:::
NP_899 AATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDK
440 450 460 470 480 490
460 470 480 490 500 510
pF1KB5 GSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYE
:::.::::::::::::.::::::.::. .:.::::::::::::: :::.:::::.:::::
NP_899 GSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYE
500 510 520 530 540 550
pF1KB5 KRLF
:::.
NP_899 KRLY
560
>>NP_001096075 (OMIM: 146690,180105,613837) inosine-5'-m (589 aa)
initn: 2907 init1: 2882 opt: 2882 Z-score: 3457.5 bits: 649.5 E(85289): 7.6e-186
Smith-Waterman score: 2882; 84.0% identity (95.3% similar) in 514 aa overlap (1-514:76-589)
10 20 30
pF1KB5 MADYLISGGTSYVPDDGLTAQQLFNCGDGL
::::::::::.:::.::::::::: .:::
NP_001 EPESCFLLELSSVVLLAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGL
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB5 TYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGF
::::::::::.::: ::.::::::::.::::::::.:::::::::: ::::::: :::::
NP_001 TYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGF
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB5 IHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRM
:::::::::::::::::::.:::::::::::::. : ::.::: :::: :::::.:: :
NP_001 IHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTM
170 180 190 200 210 220
160 170 180 190 200 210
pF1KB5 GSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLP
::.::::..::::::: :..: .: :.:: : .:::::::.::::::::::::::::::
NP_001 GSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLP
230 240 250 260 270 280
220 230 240 250 260 270
pF1KB5 IVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDV
:::. ::::::::::::::::::::::::..::::::::.::.::::::::::.::::::
NP_001 IVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDV
290 300 310 320 330 340
280 290 300 310 320 330
pF1KB5 VVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSI
.:::::::::..:: :..:::.:::.:::::::::::::::::::::::.:::::: :::
NP_001 IVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSI
350 360 370 380 390 400
340 350 360 370 380 390
pF1KB5 CITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLL
::::::.::::::.::::::.:::::::::.:::::::.:::..::::::::::::::::
NP_001 CITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLL
410 420 430 440 450 460
400 410 420 430 440 450
pF1KB5 AATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDK
:::::::::::::::.::::::::::::::.: :::.:::::.::.:.::::::..:::
NP_001 AATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDK
470 480 490 500 510 520
460 470 480 490 500 510
pF1KB5 GSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYE
:::.::::::::::::.::::::.::. .:.::::::::::::: :::.:::::.:::::
NP_001 GSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYE
530 540 550 560 570 580
pF1KB5 KRLF
:::.
NP_001 KRLY
>>NP_000874 (OMIM: 146690,180105,613837) inosine-5'-mono (599 aa)
initn: 2907 init1: 2882 opt: 2882 Z-score: 3457.4 bits: 649.5 E(85289): 7.7e-186
Smith-Waterman score: 2882; 84.0% identity (95.3% similar) in 514 aa overlap (1-514:86-599)
10 20 30
pF1KB5 MADYLISGGTSYVPDDGLTAQQLFNCGDGL
::::::::::.:::.::::::::: .:::
NP_000 THPTTPRSELSSVVLLAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGL
60 70 80 90 100 110
40 50 60 70 80 90
pF1KB5 TYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGF
::::::::::.::: ::.::::::::.::::::::.:::::::::: ::::::: :::::
NP_000 TYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGF
120 130 140 150 160 170
100 110 120 130 140 150
pF1KB5 IHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRM
:::::::::::::::::::.:::::::::::::. : ::.::: :::: :::::.:: :
NP_000 IHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTM
180 190 200 210 220 230
160 170 180 190 200 210
pF1KB5 GSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLP
::.::::..::::::: :..: .: :.:: : .:::::::.::::::::::::::::::
NP_000 GSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLP
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB5 IVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDV
:::. ::::::::::::::::::::::::..::::::::.::.::::::::::.::::::
NP_000 IVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDV
300 310 320 330 340 350
280 290 300 310 320 330
pF1KB5 VVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSI
.:::::::::..:: :..:::.:::.:::::::::::::::::::::::.:::::: :::
NP_000 IVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSI
360 370 380 390 400 410
340 350 360 370 380 390
pF1KB5 CITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLL
::::::.::::::.::::::.:::::::::.:::::::.:::..::::::::::::::::
NP_000 CITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLL
420 430 440 450 460 470
400 410 420 430 440 450
pF1KB5 AATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDK
:::::::::::::::.::::::::::::::.: :::.:::::.::.:.::::::..:::
NP_000 AATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDK
480 490 500 510 520 530
460 470 480 490 500 510
pF1KB5 GSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYE
:::.::::::::::::.::::::.::. .:.::::::::::::: :::.:::::.:::::
NP_000 GSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYE
540 550 560 570 580 590
pF1KB5 KRLF
:::.
NP_000 KRLY
>>XP_016867660 (OMIM: 146690,180105,613837) PREDICTED: i (523 aa)
initn: 2854 init1: 2854 opt: 2854 Z-score: 3424.6 bits: 643.3 E(85289): 5.2e-184
Smith-Waterman score: 2854; 84.1% identity (95.3% similar) in 509 aa overlap (1-509:9-517)
10 20 30 40 50
pF1KB5 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLT
::::::::::.:::.::::::::: .:::::::::::::.::: ::.::::
XP_016 MDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLT
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB5 SALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQ
::::.::::::::.:::::::::: ::::::: ::::::::::::::::::::::::.::
XP_016 SALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANEVRKVKKFEQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 GFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHD
:::::::::::. : ::.::: :::: :::::.:: :::.::::..::::::: :..:
XP_016 GFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB5 CFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRD
.: :.:: : .:::::::.:::::::::::::::::::::. :::::::::::::::::
XP_016 TLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRD
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB5 YPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKD
:::::::..::::::::.::.::::::::::.::::::.:::::::::..:: :..:::.
XP_016 YPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQ
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB5 KYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSE
:::.:::::::::::::::::::::::.:::::: :::::::::.::::::.::::::.:
XP_016 KYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB5 YARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYR
::::::::.:::::::.:::..:::::::::::::::::::::::::::::::.::::::
XP_016 YARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYR
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB5 GMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIG
::::::::.: :::.:::::.::.:.::::::..::::::.::::::::::::.:::::
XP_016 GMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIG
430 440 450 460 470 480
480 490 500 510
pF1KB5 AKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
:.::. .:.::::::::::::: :::.:::::.::::
XP_016 ARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYTFLPCK
490 500 510 520
>>XP_016867658 (OMIM: 146690,180105,613837) PREDICTED: i (564 aa)
initn: 2854 init1: 2854 opt: 2854 Z-score: 3424.1 bits: 643.3 E(85289): 5.5e-184
Smith-Waterman score: 2854; 84.1% identity (95.3% similar) in 509 aa overlap (1-509:50-558)
10 20 30
pF1KB5 MADYLISGGTSYVPDDGLTAQQLFNCGDGL
::::::::::.:::.::::::::: .:::
XP_016 EPGARQHPGHETAAQRYSARLLQAGYEPESMADYLISGGTGYVPEDGLTAQQLFASADGL
20 30 40 50 60 70
40 50 60 70 80 90
pF1KB5 TYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGF
::::::::::.::: ::.::::::::.::::::::.:::::::::: ::::::: :::::
XP_016 TYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGF
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB5 IHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRM
:::::::::::::::::::.:::::::::::::. : ::.::: :::: :::::.:: :
XP_016 IHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTM
140 150 160 170 180 190
160 170 180 190 200 210
pF1KB5 GSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLP
::.::::..::::::: :..: .: :.:: : .:::::::.::::::::::::::::::
XP_016 GSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLP
200 210 220 230 240 250
220 230 240 250 260 270
pF1KB5 IVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDV
:::. ::::::::::::::::::::::::..::::::::.::.::::::::::.::::::
XP_016 IVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDV
260 270 280 290 300 310
280 290 300 310 320 330
pF1KB5 VVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSI
.:::::::::..:: :..:::.:::.:::::::::::::::::::::::.:::::: :::
XP_016 IVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSI
320 330 340 350 360 370
340 350 360 370 380 390
pF1KB5 CITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLL
::::::.::::::.::::::.:::::::::.:::::::.:::..::::::::::::::::
XP_016 CITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLL
380 390 400 410 420 430
400 410 420 430 440 450
pF1KB5 AATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDK
:::::::::::::::.::::::::::::::.: :::.:::::.::.:.::::::..:::
XP_016 AATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDK
440 450 460 470 480 490
460 470 480 490 500 510
pF1KB5 GSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYE
:::.::::::::::::.::::::.::. .:.::::::::::::: :::.:::::.::::
XP_016 GSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYT
500 510 520 530 540 550
pF1KB5 KRLF
XP_016 FLPCK
560
>>XP_016867657 (OMIM: 146690,180105,613837) PREDICTED: i (590 aa)
initn: 2854 init1: 2854 opt: 2854 Z-score: 3423.9 bits: 643.3 E(85289): 5.7e-184
Smith-Waterman score: 2854; 84.1% identity (95.3% similar) in 509 aa overlap (1-509:76-584)
10 20 30
pF1KB5 MADYLISGGTSYVPDDGLTAQQLFNCGDGL
::::::::::.:::.::::::::: .:::
XP_016 EPESCFLLELSSVVLLAGVGVQMDRLRRASMADYLISGGTGYVPEDGLTAQQLFASADGL
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB5 TYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGF
::::::::::.::: ::.::::::::.::::::::.:::::::::: ::::::: :::::
XP_016 TYNDFLILPGFIDFIADEVDLTSALTRKITLKTPLISSPMDTVTEADMAIAMALMGGIGF
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB5 IHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRM
:::::::::::::::::::.:::::::::::::. : ::.::: :::: :::::.:: :
XP_016 IHHNCTPEFQANEVRKVKKFEQGFITDPVVLSPSHTVGDVLEAKMRHGFSGIPITETGTM
170 180 190 200 210 220
160 170 180 190 200 210
pF1KB5 GSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLP
::.::::..::::::: :..: .: :.:: : .:::::::.::::::::::::::::::
XP_016 GSKLVGIVTSRDIDFLAEKDHTTLLSEVMTPRIELVVAPAGVTLKEANEILQRSKKGKLP
230 240 250 260 270 280
220 230 240 250 260 270
pF1KB5 IVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDV
:::. ::::::::::::::::::::::::..::::::::.::.::::::::::.::::::
XP_016 IVNDCDELVAIIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDV
290 300 310 320 330 340
280 290 300 310 320 330
pF1KB5 VVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSI
.:::::::::..:: :..:::.:::.:::::::::::::::::::::::.:::::: :::
XP_016 IVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSI
350 360 370 380 390 400
340 350 360 370 380 390
pF1KB5 CITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLL
::::::.::::::.::::::.:::::::::.:::::::.:::..::::::::::::::::
XP_016 CITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLL
410 420 430 440 450 460
400 410 420 430 440 450
pF1KB5 AATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDK
:::::::::::::::.::::::::::::::.: :::.:::::.::.:.::::::..:::
XP_016 AATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDK
470 480 490 500 510 520
460 470 480 490 500 510
pF1KB5 GSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYE
:::.::::::::::::.::::::.::. .:.::::::::::::: :::.:::::.::::
XP_016 GSIQKFVPYLIAGIQHGCQDIGARSLSVLRSMMYSGELKFEKRTMSAQIEGGVHGLHSYT
530 540 550 560 570 580
pF1KB5 KRLF
XP_016 FLPCK
590
>>NP_001136046 (OMIM: 146690,180105,613837) inosine-5'-m (509 aa)
initn: 2829 init1: 2238 opt: 2833 Z-score: 3399.6 bits: 638.6 E(85289): 1.3e-182
Smith-Waterman score: 2833; 83.1% identity (94.4% similar) in 514 aa overlap (1-514:1-509)
10 20 30 40 50 60
pF1KB5 MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKIT
::::::::::.:::.::::::::: .:::::::::::::.::: ::.::::::::.:::
NP_001 MADYLISGGTGYVPEDGLTAQQLFASADGLTYNDFLILPGFIDFIADEVDLTSALTRKIT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVV
:::::.:::::::::: ::::::: :::::::::::::::::: :.::::::::::
NP_001 LKTPLISSPMDTVTEADMAIAMALMGGIGFIHHNCTPEFQANE-----KFEQGFITDPVV
70 80 90 100 110
130 140 150 160 170 180
pF1KB5 LSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMT
:::. : ::.::: :::: :::::.:: :::.::::..::::::: :..: .: :.::
NP_001 LSPSHTVGDVLEAKMRHGFSGIPITETGTMGSKLVGIVTSRDIDFLAEKDHTTLLSEVMT
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 KREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDA
: .:::::::.:::::::::::::::::::::. ::::::::::::::::::::::::.
NP_001 PRIELVVAPAGVTLKEANEILQRSKKGKLPIVNDCDELVAIIARTDLKKNRDYPLASKDS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB5 KKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVI
.::::::::.::.::::::::::.::::::.:::::::::..:: :..:::.:::.::::
NP_001 QKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVI
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB5 GGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVP
:::::::::::::::::::.:::::: :::::::::.::::::.::::::.:::::::::
NP_001 GGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVP
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB5 VIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAM
.:::::::.:::..:::::::::::::::::::::::::::::::.::::::::::::::
NP_001 IIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAM
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB5 DKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVR
.: :::.:::::.::.:.::::::..::::::.::::::::::::.::::::.::. .:
NP_001 EKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVLR
420 430 440 450 460 470
490 500 510
pF1KB5 AMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLF
.::::::::::::: :::.:::::.::::::::.
NP_001 SMMYSGELKFEKRTMSAQIEGGVHGLHSYEKRLY
480 490 500
514 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 22:27:47 2016 done: Fri Nov 4 22:27:48 2016
Total Scan time: 9.260 Total Display time: 0.120
Function used was FASTA [36.3.4 Apr, 2011]