Result of FASTA (omim) for
pF1KB5026
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5026, 448 aa
1>>>pF1KB5026 448 - 448 aa - 448 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.8991+/-0.000655; mu= -32.2607+/- 0.038
mean_var=792.4038+/-176.642, 0's: 0 Z-trim(114.5): 1213 B-trim: 1260 in 1/51
Lambda= 0.045562
statistics sampled from 22625 (24388) to 22625 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.645), E-opt: 0.2 (0.286), width: 16
Scan time: 9.180
The best scores are: opt bits E(85289)
NP_660143 (OMIM: 602520) dual specificity mitogen- ( 448) 3000 213.6 8.6e-55
NP_001193733 (OMIM: 602520) dual specificity mitog ( 412) 2691 193.2 1.1e-48
NP_002748 (OMIM: 602520) dual specificity mitogen- ( 438) 2293 167.1 8.3e-41
XP_011520089 (OMIM: 602520) PREDICTED: dual specif ( 289) 1857 138.3 2.7e-32
XP_011520090 (OMIM: 602520) PREDICTED: dual specif ( 283) 1856 138.2 2.7e-32
XP_016877903 (OMIM: 602520) PREDICTED: dual specif ( 267) 1751 131.3 3.1e-30
XP_011520085 (OMIM: 163950,176872,615279) PREDICTE ( 371) 808 69.4 1.8e-11
NP_002746 (OMIM: 163950,176872,615279) dual specif ( 393) 808 69.4 1.9e-11
NP_002749 (OMIM: 601254) dual specificity mitogen- ( 334) 783 67.7 5.2e-11
XP_011523328 (OMIM: 601254) PREDICTED: dual specif ( 337) 783 67.7 5.3e-11
XP_011523327 (OMIM: 601254) PREDICTED: dual specif ( 345) 783 67.7 5.3e-11
NP_109587 (OMIM: 601263,615280) dual specificity m ( 400) 781 67.7 6.5e-11
XP_016882478 (OMIM: 601263,615280) PREDICTED: dual ( 512) 781 67.8 7.6e-11
NP_001317379 (OMIM: 601254) dual specificity mitog ( 278) 764 66.4 1.1e-10
XP_006722038 (OMIM: 601254) PREDICTED: dual specif ( 278) 764 66.4 1.1e-10
XP_011523329 (OMIM: 601254) PREDICTED: dual specif ( 278) 764 66.4 1.1e-10
XP_005257573 (OMIM: 601254) PREDICTED: dual specif ( 278) 764 66.4 1.1e-10
NP_001303261 (OMIM: 602315) dual specificity mitog ( 318) 638 58.2 3.7e-08
XP_011522261 (OMIM: 602315) PREDICTED: dual specif ( 318) 638 58.2 3.7e-08
XP_016880348 (OMIM: 602315) PREDICTED: dual specif ( 318) 638 58.2 3.7e-08
NP_002747 (OMIM: 602315) dual specificity mitogen- ( 318) 638 58.2 3.7e-08
XP_016880347 (OMIM: 602315) PREDICTED: dual specif ( 318) 638 58.2 3.7e-08
XP_005256780 (OMIM: 602315) PREDICTED: dual specif ( 318) 638 58.2 3.7e-08
XP_016880346 (OMIM: 602315) PREDICTED: dual specif ( 343) 638 58.2 3.9e-08
NP_659731 (OMIM: 602315) dual specificity mitogen- ( 347) 638 58.2 4e-08
XP_016882480 (OMIM: 601263,615280) PREDICTED: dual ( 252) 631 57.6 4.4e-08
XP_006722862 (OMIM: 601263,615280) PREDICTED: dual ( 307) 633 57.8 4.6e-08
XP_016882479 (OMIM: 601263,615280) PREDICTED: dual ( 419) 633 58.0 5.7e-08
NP_660186 (OMIM: 603014) dual specificity mitogen- ( 419) 618 57.0 1.1e-07
NP_001284484 (OMIM: 603014) dual specificity mitog ( 435) 618 57.0 1.2e-07
XP_016876283 (OMIM: 604984) PREDICTED: serine/thre ( 517) 587 55.0 5.3e-07
XP_011508798 (OMIM: 602255) PREDICTED: serine/thre ( 334) 575 54.1 6.8e-07
XP_016858657 (OMIM: 602255) PREDICTED: serine/thre ( 365) 575 54.1 7.2e-07
XP_016858658 (OMIM: 602255) PREDICTED: serine/thre ( 365) 575 54.1 7.2e-07
XP_011508795 (OMIM: 602255) PREDICTED: serine/thre ( 376) 575 54.1 7.4e-07
NP_001258907 (OMIM: 602255) serine/threonine-prote ( 426) 575 54.2 8e-07
NP_001258906 (OMIM: 602255) serine/threonine-prote ( 426) 575 54.2 8e-07
NP_006365 (OMIM: 602255) serine/threonine-protein ( 426) 575 54.2 8e-07
NP_057626 (OMIM: 300547) serine/threonine-protein ( 416) 573 54.0 8.7e-07
XP_016876284 (OMIM: 604984) PREDICTED: serine/thre ( 474) 570 53.9 1.1e-06
NP_001027467 (OMIM: 604984) serine/threonine-prote ( 431) 568 53.7 1.1e-06
NP_003567 (OMIM: 604984) serine/threonine-protein ( 443) 568 53.7 1.1e-06
NP_001243241 (OMIM: 605030) serine/threonine-prote ( 519) 566 53.7 1.4e-06
XP_016869246 (OMIM: 605030) PREDICTED: serine/thre ( 524) 566 53.7 1.4e-06
XP_011515550 (OMIM: 605030) PREDICTED: serine/thre ( 576) 566 53.7 1.5e-06
XP_016869245 (OMIM: 605030) PREDICTED: serine/thre ( 580) 566 53.7 1.5e-06
XP_011527322 (OMIM: 604965,614868) PREDICTED: seri ( 404) 560 53.2 1.5e-06
XP_005256812 (OMIM: 601335) PREDICTED: dual specif ( 253) 553 52.5 1.5e-06
XP_011522279 (OMIM: 601335) PREDICTED: dual specif ( 253) 553 52.5 1.5e-06
NP_001284485 (OMIM: 603014) dual specificity mitog ( 426) 560 53.2 1.6e-06
>>NP_660143 (OMIM: 602520) dual specificity mitogen-acti (448 aa)
initn: 3000 init1: 3000 opt: 3000 Z-score: 1104.6 bits: 213.6 E(85289): 8.6e-55
Smith-Waterman score: 3000; 100.0% identity (100.0% similar) in 448 aa overlap (1-448:1-448)
10 20 30 40 50 60
pF1KB5 MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 KNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_660 KNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV
370 380 390 400 410 420
430 440
pF1KB5 QFNDGNAAVVSMWVCRALEERRSQQGPP
::::::::::::::::::::::::::::
NP_660 QFNDGNAAVVSMWVCRALEERRSQQGPP
430 440
>>NP_001193733 (OMIM: 602520) dual specificity mitogen-a (412 aa)
initn: 2691 init1: 2691 opt: 2691 Z-score: 995.3 bits: 193.2 E(85289): 1.1e-48
Smith-Waterman score: 2691; 100.0% identity (100.0% similar) in 403 aa overlap (46-448:10-412)
20 30 40 50 60 70
pF1KB5 VLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAFEYEDEDGDRITVRSD
::::::::::::::::::::::::::::::
NP_001 MMEGHFPQSDVIGQVLPEATTTAFEYEDEDGDRITVRSD
10 20 30
80 90 100 110 120 130
pF1KB5 EEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPA
40 50 60 70 80 90
140 150 160 170 180 190
pF1KB5 VSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVK
100 110 120 130 140 150
200 210 220 230 240 250
pF1KB5 VILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRKM
160 170 180 190 200 210
260 270 280 290 300 310
pF1KB5 PEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSIAKT
220 230 240 250 260 270
320 330 340 350 360 370
pF1KB5 YVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLMPLQLLQCI
280 290 300 310 320 330
380 390 400 410 420 430
pF1KB5 VDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVC
340 350 360 370 380 390
440
pF1KB5 RALEERRSQQGPP
:::::::::::::
NP_001 RALEERRSQQGPP
400 410
>>NP_002748 (OMIM: 602520) dual specificity mitogen-acti (438 aa)
initn: 2293 init1: 2293 opt: 2293 Z-score: 853.6 bits: 167.1 E(85289): 8.3e-41
Smith-Waterman score: 2897; 97.8% identity (97.8% similar) in 448 aa overlap (1-448:1-438)
10 20 30 40 50 60
pF1KB5 MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQ
:::::::::::::::::::::::::::::::::::::::::::::::: ::
NP_002 DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFME----------IQ
310 320 330 340 350
370 380 390 400 410 420
pF1KB5 KNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KNQGSLMPLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIV
360 370 380 390 400 410
430 440
pF1KB5 QFNDGNAAVVSMWVCRALEERRSQQGPP
::::::::::::::::::::::::::::
NP_002 QFNDGNAAVVSMWVCRALEERRSQQGPP
420 430
>>XP_011520089 (OMIM: 602520) PREDICTED: dual specificit (289 aa)
initn: 1856 init1: 1856 opt: 1857 Z-score: 700.9 bits: 138.3 E(85289): 2.7e-32
Smith-Waterman score: 1857; 99.3% identity (99.3% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KB5 MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC
:::::::::::::::::::::::::::::::::::::::::: :
XP_011 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRANKDLCT
250 260 270 280
310 320 330 340 350 360
pF1KB5 DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQ
>>XP_011520090 (OMIM: 602520) PREDICTED: dual specificit (283 aa)
initn: 1856 init1: 1856 opt: 1856 Z-score: 700.7 bits: 138.2 E(85289): 2.7e-32
Smith-Waterman score: 1856; 100.0% identity (100.0% similar) in 282 aa overlap (1-282:1-282)
10 20 30 40 50 60
pF1KB5 MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC
::::::::::::::::::::::::::::::::::::::::::
XP_011 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRG
250 260 270 280
310 320 330 340 350 360
pF1KB5 DFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELALGRFPYPQIQ
>>XP_016877903 (OMIM: 602520) PREDICTED: dual specificit (267 aa)
initn: 1751 init1: 1751 opt: 1751 Z-score: 663.7 bits: 131.3 E(85289): 3.1e-30
Smith-Waterman score: 1751; 100.0% identity (100.0% similar) in 266 aa overlap (1-266:1-266)
10 20 30 40 50 60
pF1KB5 MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLWLALGPFPAMENQVLVIRIKIPNSGAVDWTVHSGPQLLFRDVLDVIGQVLPEATTTAF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYEDEDGDRITVRSDEEMKAMLSYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVENRISIC
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 TEFMDGGSLDVYRKMPEHVLGRIAVAVVKGLTYLWSLKILHRDVKPSNMLVNTRGQVKLC
::::::::::::::::::::::::::
XP_016 TEFMDGGSLDVYRKMPEHVLGRIAVAQ
250 260
>>XP_011520085 (OMIM: 163950,176872,615279) PREDICTED: d (371 aa)
initn: 917 init1: 400 opt: 808 Z-score: 326.9 bits: 69.4 E(85289): 1.8e-11
Smith-Waterman score: 885; 42.6% identity (69.7% similar) in 333 aa overlap (146-438:26-357)
120 130 140 150 160 170
pF1KB5 NIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHG
:. : : . :.....:.. . :: :
XP_011 MKLERTNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAG
10 20 30 40 50
180 190 200 210 220 230
pF1KB5 NGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVEN
:::.:.:. : ::: ..: :.: :.: ...::. ::..:..:.: ::.::::::. ..
XP_011 NGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDG
60 70 80 90 100 110
240 250 260 270 280 290
pF1KB5 RISICTEFMDGGSLD-VYRK---MPEHVLGRIAVAVVKGLTYLW-SLKILHRDVKPSNML
.:::: : ::::::: : .: .::..::....::.:::::: . ::.::::::::.:
XP_011 EISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNIL
120 130 140 150 160 170
300 310 320 330 340 350
pF1KB5 VNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELA
::.::..:::::::: ::..:.:...::: .::.:::..: .:...::.::.:.:..:.:
XP_011 VNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA
180 190 200 210 220 230
360 370
pF1KB5 LGRFPYPQIQKNQGSLM---------------------PL--------------QLLQCI
.::.: : . .. :: :: .::. :
XP_011 VGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYI
240 250 260 270 280 290
380 390 400 410 420 430
pF1KB5 VDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVC
:.: : :: : :: : :...:. :.: :: ..:: : :: . .:.. . . :.:
XP_011 VNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-KRSDAEEVDFAGWLC
300 310 320 330 340 350
440
pF1KB5 RALEERRSQQGPP
..
XP_011 STIGLNQPSTPTHAAGV
360 370
>>NP_002746 (OMIM: 163950,176872,615279) dual specificit (393 aa)
initn: 917 init1: 400 opt: 808 Z-score: 326.6 bits: 69.4 E(85289): 1.9e-11
Smith-Waterman score: 885; 42.6% identity (69.7% similar) in 333 aa overlap (146-438:48-379)
120 130 140 150 160 170
pF1KB5 NIHGLKVNTRAGPSQHSSPAVSDSLPSNSLKKSSAELKKILANGQMNEQDIRYRDTLGHG
:. : : . :.....:.. . :: :
NP_002 SAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAG
20 30 40 50 60 70
180 190 200 210 220 230
pF1KB5 NGGTVYKAYHVPSGKILAVKVILLDITLELQKQIMSELEILYKCDSSYIIGFYGAFFVEN
:::.:.:. : ::: ..: :.: :.: ...::. ::..:..:.: ::.::::::. ..
NP_002 NGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDG
80 90 100 110 120 130
240 250 260 270 280 290
pF1KB5 RISICTEFMDGGSLD-VYRK---MPEHVLGRIAVAVVKGLTYLW-SLKILHRDVKPSNML
.:::: : ::::::: : .: .::..::....::.:::::: . ::.::::::::.:
NP_002 EISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNIL
140 150 160 170 180 190
300 310 320 330 340 350
pF1KB5 VNTRGQVKLCDFGVSTQLVNSIAKTYVGTNAYMAPERISGEQYGIHSDVWSLGISFMELA
::.::..:::::::: ::..:.:...::: .::.:::..: .:...::.::.:.:..:.:
NP_002 VNSRGEIKLCDFGVSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMA
200 210 220 230 240 250
360 370
pF1KB5 LGRFPYPQIQKNQGSLM---------------------PL--------------QLLQCI
.::.: : . .. :: :: .::. :
NP_002 VGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYI
260 270 280 290 300 310
380 390 400 410 420 430
pF1KB5 VDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNAAVVSMWVC
:.: : :: : :: : :...:. :.: :: ..:: : :: . .:.. . . :.:
NP_002 VNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFI-KRSDAEEVDFAGWLC
320 330 340 350 360 370
440
pF1KB5 RALEERRSQQGPP
..
NP_002 STIGLNQPSTPTHAAGV
380 390
>>NP_002749 (OMIM: 601254) dual specificity mitogen-acti (334 aa)
initn: 765 init1: 195 opt: 783 Z-score: 318.6 bits: 67.7 E(85289): 5.2e-11
Smith-Waterman score: 783; 41.6% identity (67.7% similar) in 334 aa overlap (113-431:6-326)
90 100 110 120 130 140
pF1KB5 SYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPS
:.. :::. .: .: .:.. :
NP_002 MSQSKGKKRNPGLKIPKEA----FEQPQTSSTPPR
10 20 30
150 160 170 180 190 200
pF1KB5 NSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDIT
. .:. . . : ... .:.. ::.: :.: : :::::.:.::: : ..
NP_002 DLDSKACISIGN--QNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVN
40 50 60 70 80
210 220 230 240 250
pF1KB5 LELQKQIMSELEI-LYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRK-------
. ::... .:.: . : . . ::::.: :. . :: :.:: ::: . :
NP_002 SQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDT-SLDKFYKQVIDKGQ
90 100 110 120 130 140
260 270 280 290 300 310
pF1KB5 -MPEHVLGRIAVAVVKGLTYLWS-LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSI
.:: .::.:::..::.: .: : :...::::::::.:.:. ::::.::::.: ::.:.
NP_002 TIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSV
150 160 170 180 190 200
320 330 340 350 360
pF1KB5 AKTY-VGTNAYMAPERISGEQ----YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLM
::: .: . :::::::. : :...::.:::::...:::. :::: . :.
NP_002 AKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYD----SWGT--
210 220 230 240 250 260
370 380 390 400 410 420
pF1KB5 PLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNA
:.: :. .:.: :: ::. .:: :: : .::..:. ::::. ::: :::.. .. ..
NP_002 PFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGT
270 280 290 300 310 320
430 440
pF1KB5 AVVSMWVCRALEERRSQQGPP
:.:
NP_002 DVASFVKLILGD
330
>>XP_011523328 (OMIM: 601254) PREDICTED: dual specificit (337 aa)
initn: 765 init1: 195 opt: 783 Z-score: 318.6 bits: 67.7 E(85289): 5.3e-11
Smith-Waterman score: 783; 41.6% identity (67.7% similar) in 334 aa overlap (113-431:9-329)
90 100 110 120 130 140
pF1KB5 SYYYSTVMEQQVNGQLIEPLQIFPRACKPPGERNIHGLKVNTRAGPSQHSSPAVSDSLPS
:.. :::. .: .: .:.. :
XP_011 MSHRAWAEGKKRNPGLKIPKEA----FEQPQTSSTPPR
10 20 30
150 160 170 180 190 200
pF1KB5 NSLKKSSAELKKILANGQMNEQDIRYRDTLGHGNGGTVYKAYHVPSGKILAVKVILLDIT
. .:. . . : ... .:.. ::.: :.: : :::::.:.::: : ..
XP_011 DLDSKACISIGN--QNFEVKADDLEPIMELGRGAYGVVEKMRHVPSGQIMAVKRIRATVN
40 50 60 70 80 90
210 220 230 240 250
pF1KB5 LELQKQIMSELEI-LYKCDSSYIIGFYGAFFVENRISICTEFMDGGSLDVYRK-------
. ::... .:.: . : . . ::::.: :. . :: :.:: ::: . :
XP_011 SQEQKRLLMDLDISMRTVDCPFTVTFYGALFREGDVWICMELMDT-SLDKFYKQVIDKGQ
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB5 -MPEHVLGRIAVAVVKGLTYLWS-LKILHRDVKPSNMLVNTRGQVKLCDFGVSTQLVNSI
.:: .::.:::..::.: .: : :...::::::::.:.:. ::::.::::.: ::.:.
XP_011 TIPEDILGKIAVSIVKALEHLHSKLSVIHRDVKPSNVLINALGQVKMCDFGISGYLVDSV
160 170 180 190 200 210
320 330 340 350 360
pF1KB5 AKTY-VGTNAYMAPERISGEQ----YGIHSDVWSLGISFMELALGRFPYPQIQKNQGSLM
::: .: . :::::::. : :...::.:::::...:::. :::: . :.
XP_011 AKTIDAGCKPYMAPERINPELNQKGYSVKSDIWSLGITMIELAILRFPYD----SWGT--
220 230 240 250 260
370 380 390 400 410 420
pF1KB5 PLQLLQCIVDEDSPVLPVGEFSEPFVHFITQCMRKQPKERPAPEELMGHPFIVQFNDGNA
:.: :. .:.: :: ::. .:: :: : .::..:. ::::. ::: :::.. .. ..
XP_011 PFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSKERPTYPELMQHPFFTLHESKGT
270 280 290 300 310 320
430 440
pF1KB5 AVVSMWVCRALEERRSQQGPP
:.:
XP_011 DVASFVKLILGD
330
448 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:47:11 2016 done: Thu Nov 3 15:47:13 2016
Total Scan time: 9.180 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]