Result of FASTA (omim) for
pF1KB5021
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5021, 496 aa
1>>>pF1KB5021 496 - 496 aa - 496 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.8329+/-0.00063; mu= -21.1456+/- 0.038
mean_var=670.6308+/-152.265, 0's: 0 Z-trim(115.4): 1759 B-trim: 0 in 0/53
Lambda= 0.049526
statistics sampled from 23473 (25813) to 23473 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.663), E-opt: 0.2 (0.303), width: 16
Scan time: 9.400
The best scores are: opt bits E(85289)
NP_001028750 (OMIM: 607591) serine/threonine-prote ( 496) 3354 255.9 1.9e-67
NP_037389 (OMIM: 607591) serine/threonine-protein ( 496) 3354 255.9 1.9e-67
NP_733827 (OMIM: 607591) serine/threonine-protein ( 464) 2182 172.2 2.9e-42
XP_011534373 (OMIM: 602958) PREDICTED: serine/thre ( 526) 1925 153.9 1.1e-36
NP_001137148 (OMIM: 602958) serine/threonine-prote ( 526) 1925 153.9 1.1e-36
NP_001137149 (OMIM: 602958) serine/threonine-prote ( 459) 1890 151.3 5.6e-36
NP_005618 (OMIM: 602958) serine/threonine-protein ( 431) 1887 151.0 6.2e-36
NP_001137150 (OMIM: 602958) serine/threonine-prote ( 445) 1887 151.1 6.3e-36
NP_733794 (OMIM: 607589) serine/threonine-protein ( 367) 1691 137.0 9.2e-32
NP_001186193 (OMIM: 607589) serine/threonine-prote ( 367) 1691 137.0 9.2e-32
NP_057360 (OMIM: 607589) serine/threonine-protein ( 427) 1691 137.0 1e-31
NP_001278924 (OMIM: 602958) serine/threonine-prote ( 387) 1232 104.2 7.1e-22
NP_859029 (OMIM: 611223,615937) RAC-gamma serine/t ( 465) 1095 94.5 7.1e-19
NP_001193658 (OMIM: 611223,615937) RAC-gamma serin ( 465) 1095 94.5 7.1e-19
XP_016855474 (OMIM: 611223,615937) PREDICTED: RAC- ( 418) 1091 94.1 8.1e-19
XP_005273052 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 1091 94.2 8.8e-19
NP_005456 (OMIM: 611223,615937) RAC-gamma serine/t ( 479) 1091 94.2 8.8e-19
XP_005273051 (OMIM: 611223,615937) PREDICTED: RAC- ( 479) 1091 94.2 8.8e-19
NP_001229957 (OMIM: 125853,164731,240900) RAC-beta ( 419) 1086 93.8 1e-18
NP_001229956 (OMIM: 125853,164731,240900) RAC-beta ( 419) 1086 93.8 1e-18
XP_011524922 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1086 93.9 1.1e-18
XP_011524921 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1086 93.9 1.1e-18
XP_011524920 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1086 93.9 1.1e-18
XP_011524917 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1086 93.9 1.1e-18
XP_016881959 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1086 93.9 1.1e-18
NP_001617 (OMIM: 125853,164731,240900) RAC-beta se ( 481) 1086 93.9 1.1e-18
XP_011524916 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1086 93.9 1.1e-18
XP_011524918 (OMIM: 125853,164731,240900) PREDICTE ( 481) 1086 93.9 1.1e-18
XP_005267458 (OMIM: 114480,114500,164730,167000,17 ( 480) 1041 90.6 1e-17
NP_001014432 (OMIM: 114480,114500,164730,167000,17 ( 480) 1041 90.6 1e-17
NP_001014431 (OMIM: 114480,114500,164730,167000,17 ( 480) 1041 90.6 1e-17
NP_005154 (OMIM: 114480,114500,164730,167000,17692 ( 480) 1041 90.6 1e-17
XP_011542314 (OMIM: 611223,615937) PREDICTED: RAC- ( 435) 1017 88.9 3.2e-17
NP_001258972 (OMIM: 608938) ribosomal protein S6 k ( 451) 1016 88.8 3.5e-17
NP_001258973 (OMIM: 608938) ribosomal protein S6 k ( 472) 1016 88.9 3.6e-17
NP_001258989 (OMIM: 608938) ribosomal protein S6 k ( 502) 1016 88.9 3.7e-17
NP_003152 (OMIM: 608938) ribosomal protein S6 kina ( 525) 1016 88.9 3.8e-17
NP_003943 (OMIM: 608939) ribosomal protein S6 kina ( 482) 1008 88.3 5.4e-17
XP_011531285 (OMIM: 176975) PREDICTED: protein kin ( 436) 995 87.3 9.6e-17
XP_006712113 (OMIM: 176975) PREDICTED: protein kin ( 460) 995 87.3 9.9e-17
XP_011531284 (OMIM: 176975) PREDICTED: protein kin ( 497) 995 87.4 1e-16
XP_016859979 (OMIM: 176975) PREDICTED: protein kin ( 587) 995 87.5 1.2e-16
XP_016859980 (OMIM: 176975) PREDICTED: protein kin ( 587) 995 87.5 1.2e-16
XP_011531282 (OMIM: 176975) PREDICTED: protein kin ( 587) 995 87.5 1.2e-16
XP_016859978 (OMIM: 176975) PREDICTED: protein kin ( 587) 995 87.5 1.2e-16
XP_011531283 (OMIM: 176975) PREDICTED: protein kin ( 587) 995 87.5 1.2e-16
XP_011531280 (OMIM: 176975) PREDICTED: protein kin ( 623) 995 87.5 1.2e-16
XP_016859976 (OMIM: 176975) PREDICTED: protein kin ( 623) 995 87.5 1.2e-16
XP_016859977 (OMIM: 176975) PREDICTED: protein kin ( 623) 995 87.5 1.2e-16
XP_011531277 (OMIM: 176975) PREDICTED: protein kin ( 641) 995 87.5 1.2e-16
>>NP_001028750 (OMIM: 607591) serine/threonine-protein k (496 aa)
initn: 3354 init1: 3354 opt: 3354 Z-score: 1331.9 bits: 255.9 E(85289): 1.9e-67
Smith-Waterman score: 3354; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KB5 MQRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 SPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 DFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 VLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 FYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADD
430 440 450 460 470 480
490
pF1KB5 AFVGFSYAPPSEDLFL
::::::::::::::::
NP_001 AFVGFSYAPPSEDLFL
490
>>NP_037389 (OMIM: 607591) serine/threonine-protein kina (496 aa)
initn: 3354 init1: 3354 opt: 3354 Z-score: 1331.9 bits: 255.9 E(85289): 1.9e-67
Smith-Waterman score: 3354; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KB5 MQRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MQRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 SPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 RKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 DFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 VLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 FYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 FYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 SLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADD
430 440 450 460 470 480
490
pF1KB5 AFVGFSYAPPSEDLFL
::::::::::::::::
NP_037 AFVGFSYAPPSEDLFL
490
>>NP_733827 (OMIM: 607591) serine/threonine-protein kina (464 aa)
initn: 3107 init1: 2179 opt: 2182 Z-score: 879.6 bits: 172.2 E(85289): 2.9e-42
Smith-Waterman score: 3047; 93.5% identity (93.5% similar) in 496 aa overlap (1-496:1-464)
10 20 30 40 50 60
pF1KB5 MQRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 MQRDHTMDYKESCPSVSIPSSDEHREKKKRFTVYKVLVSVGRSEWFVFRRYAEFDKLYNT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 LKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRAFLQMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 SPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 SPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGKVLLAK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 RKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 RKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEKLYFVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 DFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 DFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSVGHV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 VLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPP
:::::::::::::::::::::::::: ::
NP_733 VLTDFGLCKEGIAISDTTTTFCGTPE--------------------------------PP
310 320
370 380 390 400 410 420
pF1KB5 FYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 FYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQNHPFFE
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB5 SLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_733 SLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASVLEADD
390 400 410 420 430 440
490
pF1KB5 AFVGFSYAPPSEDLFL
::::::::::::::::
NP_733 AFVGFSYAPPSEDLFL
450 460
>>XP_011534373 (OMIM: 602958) PREDICTED: serine/threonin (526 aa)
initn: 1911 init1: 1790 opt: 1925 Z-score: 779.8 bits: 153.9 E(85289): 1.1e-36
Smith-Waterman score: 1925; 67.2% identity (84.2% similar) in 430 aa overlap (67-496:103-526)
40 50 60 70 80 90
pF1KB5 LVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNE
: : : : : : :: :.:::: :::.
XP_011 AFQRGVLPQENESCSWETQSGCEVREPCNHANILTKPDPRTFWTNDDPAFMKQRRMGLND
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB5 FIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPH
:::... .::.:...:....:. .: : . : : ::.::::::.:::
XP_011 FIQKIANNSYACKHPEVQSILKISQPQ---EP-ELMNANPSPP-PSPSQQINLGPSSNPH
140 150 160 170 180
160 170 180 190 200 210
pF1KB5 AKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLK
:::.:: ::::::::::::::::..: . :::::::::: .:..::.::::.:::::::
XP_011 AKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLK
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 NVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGY
:::::::::::.::::..:::::::..::::::.:::::: : : :::::::::::::::
XP_011 NVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGY
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 LHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQ
:::..::::::::::::::: ::.::::::::::.: ..::.:::::::::::::..::
XP_011 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 PYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELL
::: :::::::::::::::::::::: :..::::::::.:::.:.:... .: .:: ::
XP_011 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 EKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEE
.::: .:::::.::.::..: :: ..: ::..::: :::::::.::.:.:.:: ::::
XP_011 QKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEE
430 440 450 460 470 480
460 470 480 490
pF1KB5 TVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSEDLFL
:: :. : : .:.::: :: .::.:::::::. : ::
XP_011 PVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPT-DSFL
490 500 510 520
>>NP_001137148 (OMIM: 602958) serine/threonine-protein k (526 aa)
initn: 1911 init1: 1790 opt: 1925 Z-score: 779.8 bits: 153.9 E(85289): 1.1e-36
Smith-Waterman score: 1925; 67.2% identity (84.2% similar) in 430 aa overlap (67-496:103-526)
40 50 60 70 80 90
pF1KB5 LVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNE
: : : : : : :: :.:::: :::.
NP_001 AFQRGVLPQENESCSWETQSGCEVREPCNHANILTKPDPRTFWTNDDPAFMKQRRMGLND
80 90 100 110 120 130
100 110 120 130 140 150
pF1KB5 FIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPH
:::... .::.:...:....:. .: : . : : ::.::::::.:::
NP_001 FIQKIANNSYACKHPEVQSILKISQPQ---EP-ELMNANPSPP-PSPSQQINLGPSSNPH
140 150 160 170 180
160 170 180 190 200 210
pF1KB5 AKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLK
:::.:: ::::::::::::::::..: . :::::::::: .:..::.::::.:::::::
NP_001 AKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLK
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB5 NVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGY
:::::::::::.::::..:::::::..::::::.:::::: : : :::::::::::::::
NP_001 NVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGY
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB5 LHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQ
:::..::::::::::::::: ::.::::::::::.: ..::.:::::::::::::..::
NP_001 LHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQ
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB5 PYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELL
::: :::::::::::::::::::::: :..::::::::.:::.:.:... .: .:: ::
NP_001 PYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB5 EKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEE
.::: .:::::.::.::..: :: ..: ::..::: :::::::.::.:.:.:: ::::
NP_001 QKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEE
430 440 450 460 470 480
460 470 480 490
pF1KB5 TVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSEDLFL
:: :. : : .:.::: :: .::.:::::::. : ::
NP_001 PVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPT-DSFL
490 500 510 520
>>NP_001137149 (OMIM: 602958) serine/threonine-protein k (459 aa)
initn: 1895 init1: 1790 opt: 1890 Z-score: 766.9 bits: 151.3 E(85289): 5.6e-36
Smith-Waterman score: 1890; 65.7% identity (83.6% similar) in 434 aa overlap (66-496:32-459)
40 50 60 70 80 90
pF1KB5 VLVSVGRSEWFVFRRYAEFDKLYNTLKKQFPAMALKIPAKRIFGDNFDPD---FIKQRRA
: : ..:. . . : :.::::
NP_001 SSQSSSLSEACSREAYSSHNWALPPASRSNPQPAYPWATRRMKEEAIKPPLKAFMKQRRM
10 20 30 40 50 60
100 110 120 130 140 150
pF1KB5 GLNEFIQNLVRYPELYNHPDVRAFLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPS
:::.:::... .::.:...:....:. .: : . : : ::.::::::
NP_001 GLNDFIQKIANNSYACKHPEVQSILKISQPQ---EP-ELMNANPSPP-PSPSQQINLGPS
70 80 90 100 110
160 170 180 190 200 210
pF1KB5 GNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERN
.::::::.:: ::::::::::::::::..: . :::::::::: .:..::.::::.:::
NP_001 SNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERN
120 130 140 150 160 170
220 230 240 250 260 270
pF1KB5 VLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIAS
:::::::::::::::.::::..:::::::..::::::.:::::: : : :::::::::::
NP_001 VLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIAS
180 190 200 210 220 230
280 290 300 310 320 330
pF1KB5 ALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEV
:::::::..::::::::::::::: ::.::::::::::.: ..::.:::::::::::::
NP_001 ALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEV
240 250 260 270 280 290
340 350 360 370 380 390
pF1KB5 IRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSIL
..::::: :::::::::::::::::::::: :..::::::::.:::.:.:... .: .:
NP_001 LHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLL
300 310 320 330 340 350
400 410 420 430 440 450
pF1KB5 EELLEKDRQNRLGAKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTA
: ::.::: .:::::.::.::..: :: ..: ::..::: :::::::.::.:.:.::
NP_001 EGLLQKDRTKRLGAKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPE
360 370 380 390 400 410
460 470 480 490
pF1KB5 FTEETVPYSVCVSSDYSIVNASVLEADDAFVGFSYAPPSEDLFL
:::: :: :. : : .:.::: :: .::.:::::::. : ::
NP_001 FTEEPVPNSIGKSPDSVLVTASVKEAAEAFLGFSYAPPT-DSFL
420 430 440 450
>>NP_005618 (OMIM: 602958) serine/threonine-protein kina (431 aa)
initn: 1895 init1: 1790 opt: 1887 Z-score: 766.1 bits: 151.0 E(85289): 6.2e-36
Smith-Waterman score: 1887; 68.4% identity (86.1% similar) in 411 aa overlap (86-496:27-431)
60 70 80 90 100 110
pF1KB5 KLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRA
:.:::: :::.:::... .::.:..
NP_005 MTVKTEAAKGTLTYSRMRGMVAILIAFMKQRRMGLNDFIQKIANNSYACKHPEVQS
10 20 30 40 50
120 130 140 150 160 170
pF1KB5 FLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGK
.:....:. .: : . : : ::.::::::.::::::.:: ::::::::::::
NP_005 ILKISQPQ---EP-ELMNANPSPP-PSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGK
60 70 80 90 100 110
180 190 200 210 220 230
pF1KB5 VLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEK
::::..: . :::::::::: .:..::.::::.::::::::::::::::::.::::..:
NP_005 VLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADK
120 130 140 150 160 170
240 250 260 270 280 290
pF1KB5 LYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLD
::::::..::::::.:::::: : : ::::::::::::::::::..::::::::::::::
NP_005 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD
180 190 200 210 220 230
300 310 320 330 340 350
pF1KB5 SVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEML
: ::.::::::::::.: ..::.:::::::::::::..::::: :::::::::::::::
NP_005 SQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEML
240 250 260 270 280 290
360 370 380 390 400 410
pF1KB5 YGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQN
::::::: :..::::::::.:::.:.:... .: .:: ::.::: .:::::.::.::..
NP_005 YGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKS
300 310 320 330 340 350
420 430 440 450 460 470
pF1KB5 HPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASV
: :: ..: ::..::: :::::::.::.:.:.:: :::: :: :. : : .:.:::
NP_005 HVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASV
360 370 380 390 400 410
480 490
pF1KB5 LEADDAFVGFSYAPPSEDLFL
:: .::.:::::::. : ::
NP_005 KEAAEAFLGFSYAPPT-DSFL
420 430
>>NP_001137150 (OMIM: 602958) serine/threonine-protein k (445 aa)
initn: 1895 init1: 1790 opt: 1887 Z-score: 765.9 bits: 151.1 E(85289): 6.3e-36
Smith-Waterman score: 1887; 68.4% identity (86.1% similar) in 411 aa overlap (86-496:41-445)
60 70 80 90 100 110
pF1KB5 KLYNTLKKQFPAMALKIPAKRIFGDNFDPDFIKQRRAGLNEFIQNLVRYPELYNHPDVRA
:.:::: :::.:::... .::.:..
NP_001 ARLESLLRPRHKKRAEAQKRSESFLLSGLAFMKQRRMGLNDFIQKIANNSYACKHPEVQS
20 30 40 50 60 70
120 130 140 150 160 170
pF1KB5 FLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGK
.:....:. .: : . : : ::.::::::.::::::.:: ::::::::::::
NP_001 ILKISQPQ---EP-ELMNANPSPP-PSPSQQINLGPSSNPHAKPSDFHFLKVIGKGSFGK
80 90 100 110 120
180 190 200 210 220 230
pF1KB5 VLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEK
::::..: . :::::::::: .:..::.::::.::::::::::::::::::.::::..:
NP_001 VLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLHFSFQTADK
130 140 150 160 170 180
240 250 260 270 280 290
pF1KB5 LYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLD
::::::..::::::.:::::: : : ::::::::::::::::::..::::::::::::::
NP_001 LYFVLDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDLKPENILLD
190 200 210 220 230 240
300 310 320 330 340 350
pF1KB5 SVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEML
: ::.::::::::::.: ..::.:::::::::::::..::::: :::::::::::::::
NP_001 SQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCLGAVLYEML
250 260 270 280 290 300
360 370 380 390 400 410
pF1KB5 YGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQN
::::::: :..::::::::.:::.:.:... .: .:: ::.::: .:::::.::.::..
NP_001 YGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARHLLEGLLQKDRTKRLGAKDDFMEIKS
310 320 330 340 350 360
420 430 440 450 460 470
pF1KB5 HPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASV
: :: ..: ::..::: :::::::.::.:.:.:: :::: :: :. : : .:.:::
NP_001 HVFFSLINWDDLINKKITPPFNPNVSGPNDLRHFDPEFTEEPVPNSIGKSPDSVLVTASV
370 380 390 400 410 420
480 490
pF1KB5 LEADDAFVGFSYAPPSEDLFL
:: .::.:::::::. : ::
NP_001 KEAAEAFLGFSYAPPT-DSFL
430 440
>>NP_733794 (OMIM: 607589) serine/threonine-protein kina (367 aa)
initn: 1695 init1: 1632 opt: 1691 Z-score: 691.2 bits: 137.0 E(85289): 9.2e-32
Smith-Waterman score: 1691; 69.4% identity (88.9% similar) in 350 aa overlap (146-495:19-365)
120 130 140 150 160 170
pF1KB5 FLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGK
:::::::.::.:.:::::::::::::..::
NP_733 MNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGK
10 20 30 40
180 190 200 210 220 230
pF1KB5 VLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEK
::::::: :: :::::::::: .:..:::.::::::.::::::.:::::::.::::: ::
NP_733 VLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEK
50 60 70 80 90 100
240 250 260 270 280 290
pF1KB5 LYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLD
::::::.:::::::::::::: : : ::::::::.:::.:::::..:.::::::::::::
NP_733 LYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLD
110 120 130 140 150 160
300 310 320 330 340 350
pF1KB5 SVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEML
::::::::::::::. :::.:::::::::::::.::.::: .::::::::::::::
NP_733 CQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEML
170 180 190 200 210 220
360 370 380 390 400 410
pF1KB5 YGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQN
.:::::: .::..::.::::.::.. : ...: ..:. ::.::...:::.: :::::.:
NP_733 HGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKN
230 240 250 260 270 280
420 430 440 450 460 470
pF1KB5 HPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASV
: :: ..: :: .:.. :::::::.:: :...:: ::.:.: :. . : .....:
NP_733 HVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPD-TVASSS-
290 300 310 320 330 340
480 490
pF1KB5 LEADDAFVGFSYAPPSEDLFL
:..::.:::::: ..:..
NP_733 -GASSAFLGFSYAPEDDDILDC
350 360
>>NP_001186193 (OMIM: 607589) serine/threonine-protein k (367 aa)
initn: 1695 init1: 1632 opt: 1691 Z-score: 691.2 bits: 137.0 E(85289): 9.2e-32
Smith-Waterman score: 1691; 69.4% identity (88.9% similar) in 350 aa overlap (146-495:19-365)
120 130 140 150 160 170
pF1KB5 FLQMDSPKHQSDPSEDEDERSSQKLHSTSQNINLGPSGNPHAKPTDFDFLKVIGKGSFGK
:::::::.::.:.:::::::::::::..::
NP_001 MNSSPAGTPSPQPSRANGNINLGPSANPNAQPTDFDFLKVIGKGNYGK
10 20 30 40
180 190 200 210 220 230
pF1KB5 VLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTEK
::::::: :: :::::::::: .:..:::.::::::.::::::.:::::::.::::: ::
NP_001 VLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSFQTPEK
50 60 70 80 90 100
240 250 260 270 280 290
pF1KB5 LYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLHSIKIVYRDLKPENILLD
::::::.:::::::::::::: : : ::::::::.:::.:::::..:.::::::::::::
NP_001 LYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLD
110 120 130 140 150 160
300 310 320 330 340 350
pF1KB5 SVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEML
::::::::::::::. :::.:::::::::::::.::.::: .::::::::::::::
NP_001 CQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEML
170 180 190 200 210 220
360 370 380 390 400 410
pF1KB5 YGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWSILEELLEKDRQNRLGAKEDFLEIQN
.:::::: .::..::.::::.::.. : ...: ..:. ::.::...:::.: :::::.:
NP_001 HGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACDLLQSLLHKDQRQRLGSKADFLEIKN
230 240 250 260 270 280
420 430 440 450 460 470
pF1KB5 HPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNFDTAFTEETVPYSVCVSSDYSIVNASV
: :: ..: :: .:.. :::::::.:: :...:: ::.:.: :. . : .....:
NP_001 HVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHFDPEFTQEAVSKSIGCTPD-TVASSS-
290 300 310 320 330 340
480 490
pF1KB5 LEADDAFVGFSYAPPSEDLFL
:..::.:::::: ..:..
NP_001 -GASSAFLGFSYAPEDDDILDC
350 360
496 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 22:13:11 2016 done: Thu Nov 3 22:13:13 2016
Total Scan time: 9.400 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]