Result of FASTA (omim) for
pF1KB4980
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4980, 847 aa
1>>>pF1KB4980 847 - 847 aa - 847 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.0487+/-0.000435; mu= 3.1374+/- 0.027
mean_var=210.1618+/-43.821, 0's: 0 Z-trim(117.4): 49 B-trim: 0 in 0/53
Lambda= 0.088470
statistics sampled from 29324 (29373) to 29324 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.344), width: 16
Scan time: 13.840
The best scores are: opt bits E(85289)
XP_006719638 (OMIM: 601512) PREDICTED: signal tran ( 847) 5724 744.2 5.7e-214
NP_001171549 (OMIM: 601512) signal transducer and ( 847) 5724 744.2 5.7e-214
NP_003144 (OMIM: 601512) signal transducer and act ( 847) 5724 744.2 5.7e-214
NP_001171550 (OMIM: 601512) signal transducer and ( 847) 5724 744.2 5.7e-214
NP_001171551 (OMIM: 601512) signal transducer and ( 737) 4983 649.6 1.5e-185
NP_001171552 (OMIM: 601512) signal transducer and ( 737) 4983 649.6 1.5e-185
XP_011537007 (OMIM: 601512) PREDICTED: signal tran ( 865) 3358 442.2 4.6e-123
XP_011537009 (OMIM: 601512) PREDICTED: signal tran ( 865) 3358 442.2 4.6e-123
XP_011537008 (OMIM: 601512) PREDICTED: signal tran ( 865) 3358 442.2 4.6e-123
XP_011537006 (OMIM: 601512) PREDICTED: signal tran ( 865) 3358 442.2 4.6e-123
XP_011537005 (OMIM: 601512) PREDICTED: signal tran ( 865) 3358 442.2 4.6e-123
XP_011537011 (OMIM: 601512) PREDICTED: signal tran ( 755) 2617 347.6 1.2e-94
XP_011537010 (OMIM: 601512) PREDICTED: signal tran ( 755) 2617 347.6 1.2e-94
NP_001275648 (OMIM: 601511) signal transducer and ( 764) 1466 200.7 2.1e-50
XP_016880466 (OMIM: 245590,604260) PREDICTED: sign ( 693) 1461 200.1 3e-50
NP_036580 (OMIM: 245590,604260) signal transducer ( 787) 1461 200.1 3.3e-50
NP_003143 (OMIM: 601511) signal transducer and act ( 794) 1461 200.1 3.3e-50
NP_001275647 (OMIM: 601511) signal transducer and ( 794) 1461 200.1 3.3e-50
XP_005257681 (OMIM: 601511) PREDICTED: signal tran ( 761) 1432 196.4 4.2e-49
NP_001275649 (OMIM: 601511) signal transducer and ( 763) 761 110.7 2.5e-23
XP_005257683 (OMIM: 245590,604260) PREDICTED: sign ( 497) 703 103.2 3.1e-21
XP_016880464 (OMIM: 102582,147060,615952) PREDICTE ( 769) 603 90.6 3e-17
XP_005257673 (OMIM: 102582,147060,615952) PREDICTE ( 769) 603 90.6 3e-17
NP_003141 (OMIM: 102582,147060,615952) signal tran ( 769) 603 90.6 3e-17
XP_011523447 (OMIM: 102582,147060,615952) PREDICTE ( 770) 603 90.6 3e-17
XP_005257674 (OMIM: 102582,147060,615952) PREDICTE ( 770) 603 90.6 3e-17
NP_644805 (OMIM: 102582,147060,615952) signal tran ( 770) 603 90.6 3e-17
XP_016880465 (OMIM: 102582,147060,615952) PREDICTE ( 721) 595 89.5 5.8e-17
XP_016880463 (OMIM: 102582,147060,615952) PREDICTE ( 721) 595 89.5 5.8e-17
XP_016880462 (OMIM: 102582,147060,615952) PREDICTE ( 721) 595 89.5 5.8e-17
XP_011523448 (OMIM: 102582,147060,615952) PREDICTE ( 722) 595 89.5 5.8e-17
XP_016880461 (OMIM: 102582,147060,615952) PREDICTE ( 722) 595 89.5 5.8e-17
NP_998827 (OMIM: 102582,147060,615952) signal tran ( 722) 595 89.5 5.8e-17
XP_011510007 (OMIM: 600558,612253) PREDICTED: sign ( 748) 563 85.5 1e-15
NP_003142 (OMIM: 600558,612253) signal transducer ( 748) 563 85.5 1e-15
XP_006712782 (OMIM: 600558,612253) PREDICTED: sign ( 748) 563 85.5 1e-15
NP_001230764 (OMIM: 600558,612253) signal transduc ( 748) 563 85.5 1e-15
NP_644671 (OMIM: 600555,613796,614162,614892) sign ( 712) 550 83.8 3.1e-15
NP_009330 (OMIM: 600555,613796,614162,614892) sign ( 750) 550 83.8 3.2e-15
XP_006712781 (OMIM: 600555,613796,614162,614892) P ( 750) 550 83.8 3.2e-15
XP_016860272 (OMIM: 600555,613796,614162,614892) P ( 752) 550 83.8 3.2e-15
NP_938146 (OMIM: 600556,616636) signal transducer ( 847) 530 81.3 2.1e-14
NP_005410 (OMIM: 600556,616636) signal transducer ( 851) 530 81.3 2.1e-14
XP_016875393 (OMIM: 600556,616636) PREDICTED: sign ( 607) 479 74.7 1.5e-12
XP_011537002 (OMIM: 600556,616636) PREDICTED: sign ( 615) 446 70.5 2.7e-11
XP_011537000 (OMIM: 600556,616636) PREDICTED: sign ( 855) 446 70.6 3.5e-11
XP_011536999 (OMIM: 600556,616636) PREDICTED: sign ( 859) 446 70.6 3.6e-11
XP_011537001 (OMIM: 600556,616636) PREDICTED: sign ( 592) 248 45.2 0.0011
>>XP_006719638 (OMIM: 601512) PREDICTED: signal transduc (847 aa)
initn: 5724 init1: 5724 opt: 5724 Z-score: 3962.5 bits: 744.2 E(85289): 5.7e-214
Smith-Waterman score: 5724; 100.0% identity (100.0% similar) in 847 aa overlap (1-847:1-847)
10 20 30 40 50 60
pF1KB4 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD
790 800 810 820 830 840
pF1KB4 LRANPSW
:::::::
XP_006 LRANPSW
>>NP_001171549 (OMIM: 601512) signal transducer and acti (847 aa)
initn: 5724 init1: 5724 opt: 5724 Z-score: 3962.5 bits: 744.2 E(85289): 5.7e-214
Smith-Waterman score: 5724; 100.0% identity (100.0% similar) in 847 aa overlap (1-847:1-847)
10 20 30 40 50 60
pF1KB4 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD
790 800 810 820 830 840
pF1KB4 LRANPSW
:::::::
NP_001 LRANPSW
>>NP_003144 (OMIM: 601512) signal transducer and activat (847 aa)
initn: 5724 init1: 5724 opt: 5724 Z-score: 3962.5 bits: 744.2 E(85289): 5.7e-214
Smith-Waterman score: 5724; 100.0% identity (100.0% similar) in 847 aa overlap (1-847:1-847)
10 20 30 40 50 60
pF1KB4 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD
790 800 810 820 830 840
pF1KB4 LRANPSW
:::::::
NP_003 LRANPSW
>>NP_001171550 (OMIM: 601512) signal transducer and acti (847 aa)
initn: 5724 init1: 5724 opt: 5724 Z-score: 3962.5 bits: 744.2 E(85289): 5.7e-214
Smith-Waterman score: 5724; 100.0% identity (100.0% similar) in 847 aa overlap (1-847:1-847)
10 20 30 40 50 60
pF1KB4 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD
790 800 810 820 830 840
pF1KB4 LRANPSW
:::::::
NP_001 LRANPSW
>>NP_001171551 (OMIM: 601512) signal transducer and acti (737 aa)
initn: 4983 init1: 4983 opt: 4983 Z-score: 3452.2 bits: 649.6 E(85289): 1.5e-185
Smith-Waterman score: 4983; 100.0% identity (100.0% similar) in 737 aa overlap (111-847:1-737)
90 100 110 120 130 140
pF1KB4 ISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMPFHWKQEELKFKTGLRRLQHR
::::::::::::::::::::::::::::::
NP_001 MEQFRHLPMPFHWKQEELKFKTGLRRLQHR
10 20 30
150 160 170 180 190 200
pF1KB4 VGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALAMLLQETTGELEAAKALVLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALAMLLQETTGELEAAKALVLKR
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB4 IQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQEVGAAGGELEPKTRASLTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQEVGAAGGELEPKTRASLTGR
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB4 LDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLRFLGAPAKPPLVRADMVTEKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLRFLGAPAKPPLVRADMVTEKQ
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB4 ARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALFKNLLLKKIKRCERKGTESVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALFKNLLLKKIKRCERKGTESVT
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB4 EEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDNNAKATILWDNAFSEMDRVPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDNNAKATILWDNAFSEMDRVPF
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB4 VVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDNSLSMEAFQHRSVSWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDNSLSMEAFQHRSVSWS
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB4 QFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFL
400 410 420 430 440 450
570 580 590 600 610 620
pF1KB4 LRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKP
460 470 480 490 500 510
630 640 650 660 670 680
pF1KB4 KDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSM
520 530 540 550 560 570
690 700 710 720 730 740
pF1KB4 SMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPH
580 590 600 610 620 630
750 760 770 780 790 800
pF1KB4 PQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQ
640 650 660 670 680 690
810 820 830 840
pF1KB4 DLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMDLRANPSW
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMDLRANPSW
700 710 720 730
>>NP_001171552 (OMIM: 601512) signal transducer and acti (737 aa)
initn: 4983 init1: 4983 opt: 4983 Z-score: 3452.2 bits: 649.6 E(85289): 1.5e-185
Smith-Waterman score: 4983; 100.0% identity (100.0% similar) in 737 aa overlap (111-847:1-737)
90 100 110 120 130 140
pF1KB4 ISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMPFHWKQEELKFKTGLRRLQHR
::::::::::::::::::::::::::::::
NP_001 MEQFRHLPMPFHWKQEELKFKTGLRRLQHR
10 20 30
150 160 170 180 190 200
pF1KB4 VGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALAMLLQETTGELEAAKALVLKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALAMLLQETTGELEAAKALVLKR
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB4 IQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQEVGAAGGELEPKTRASLTGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQEVGAAGGELEPKTRASLTGR
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB4 LDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLRFLGAPAKPPLVRADMVTEKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLRFLGAPAKPPLVRADMVTEKQ
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB4 ARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALFKNLLLKKIKRCERKGTESVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALFKNLLLKKIKRCERKGTESVT
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB4 EEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDNNAKATILWDNAFSEMDRVPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDNNAKATILWDNAFSEMDRVPF
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB4 VVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDNSLSMEAFQHRSVSWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQKIFNDNSLSMEAFQHRSVSWS
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB4 QFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFL
400 410 420 430 440 450
570 580 590 600 610 620
pF1KB4 LRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKP
460 470 480 490 500 510
630 640 650 660 670 680
pF1KB4 KDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSM
520 530 540 550 560 570
690 700 710 720 730 740
pF1KB4 SMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPH
580 590 600 610 620 630
750 760 770 780 790 800
pF1KB4 PQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQ
640 650 660 670 680 690
810 820 830 840
pF1KB4 DLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMDLRANPSW
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMDLRANPSW
700 710 720 730
>>XP_011537007 (OMIM: 601512) PREDICTED: signal transduc (865 aa)
initn: 3332 init1: 3332 opt: 3358 Z-score: 2330.3 bits: 442.2 E(85289): 4.6e-123
Smith-Waterman score: 5678; 97.9% identity (97.9% similar) in 865 aa overlap (1-847:1-865)
10 20 30 40 50 60
pF1KB4 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
430 440 450 460 470 480
490 500 510 520
pF1KB4 IFNDNSLSMEAFQHRSVSWSQFNK------------------EILLGRGFTFWQWFDGVL
:::::::::::::::::::::::: ::::::::::::::::::
XP_011 IFNDNSLSMEAFQHRSVSWSQFNKMRNLMLRGLCSLFKFPKQEILLGRGFTFWQWFDGVL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB4 DLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDG
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB4 SPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB4 PATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPP
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB4 YQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLC
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB4 SDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQP
790 800 810 820 830 840
830 840
pF1KB4 LLQPSHYGQSGISMSHMDLRANPSW
:::::::::::::::::::::::::
XP_011 LLQPSHYGQSGISMSHMDLRANPSW
850 860
>>XP_011537009 (OMIM: 601512) PREDICTED: signal transduc (865 aa)
initn: 3332 init1: 3332 opt: 3358 Z-score: 2330.3 bits: 442.2 E(85289): 4.6e-123
Smith-Waterman score: 5678; 97.9% identity (97.9% similar) in 865 aa overlap (1-847:1-865)
10 20 30 40 50 60
pF1KB4 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
430 440 450 460 470 480
490 500 510 520
pF1KB4 IFNDNSLSMEAFQHRSVSWSQFNK------------------EILLGRGFTFWQWFDGVL
:::::::::::::::::::::::: ::::::::::::::::::
XP_011 IFNDNSLSMEAFQHRSVSWSQFNKMRNLMLRGLCSLFKFPKQEILLGRGFTFWQWFDGVL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB4 DLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDG
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB4 SPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB4 PATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPP
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB4 YQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLC
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB4 SDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQP
790 800 810 820 830 840
830 840
pF1KB4 LLQPSHYGQSGISMSHMDLRANPSW
:::::::::::::::::::::::::
XP_011 LLQPSHYGQSGISMSHMDLRANPSW
850 860
>>XP_011537008 (OMIM: 601512) PREDICTED: signal transduc (865 aa)
initn: 3332 init1: 3332 opt: 3358 Z-score: 2330.3 bits: 442.2 E(85289): 4.6e-123
Smith-Waterman score: 5678; 97.9% identity (97.9% similar) in 865 aa overlap (1-847:1-865)
10 20 30 40 50 60
pF1KB4 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
430 440 450 460 470 480
490 500 510 520
pF1KB4 IFNDNSLSMEAFQHRSVSWSQFNK------------------EILLGRGFTFWQWFDGVL
:::::::::::::::::::::::: ::::::::::::::::::
XP_011 IFNDNSLSMEAFQHRSVSWSQFNKMRNLMLRGLCSLFKFPKQEILLGRGFTFWQWFDGVL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB4 DLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDG
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB4 SPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB4 PATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPP
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB4 YQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLC
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB4 SDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQP
790 800 810 820 830 840
830 840
pF1KB4 LLQPSHYGQSGISMSHMDLRANPSW
:::::::::::::::::::::::::
XP_011 LLQPSHYGQSGISMSHMDLRANPSW
850 860
>>XP_011537006 (OMIM: 601512) PREDICTED: signal transduc (865 aa)
initn: 3332 init1: 3332 opt: 3358 Z-score: 2330.3 bits: 442.2 E(85289): 4.6e-123
Smith-Waterman score: 5678; 97.9% identity (97.9% similar) in 865 aa overlap (1-847:1-865)
10 20 30 40 50 60
pF1KB4 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNLASALLSDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVMEQFRHLPMP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLGAPAKPPLVRADMVTEKQARELSVPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
430 440 450 460 470 480
490 500 510 520
pF1KB4 IFNDNSLSMEAFQHRSVSWSQFNK------------------EILLGRGFTFWQWFDGVL
:::::::::::::::::::::::: ::::::::::::::::::
XP_011 IFNDNSLSMEAFQHRSVSWSQFNKMRNLMLRGLCSLFKFPKQEILLGRGFTFWQWFDGVL
490 500 510 520 530 540
530 540 550 560 570 580
pF1KB4 DLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLTKRCLRSYWSDRLIIGFISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDG
550 560 570 580 590 600
590 600 610 620 630 640
pF1KB4 SPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPQIENIQPFSAKDLSIRSLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYV
610 620 630 640 650 660
650 660 670 680 690 700
pF1KB4 PATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PATIKMTVERDQPLPTPELQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPP
670 680 690 700 710 720
710 720 730 740 750 760
pF1KB4 YQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YQGLSPEESVNVLSAFQEPHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLC
730 740 750 760 770 780
770 780 790 800 810 820
pF1KB4 SDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SDVTMVEDSCLSQPVTAFPQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQP
790 800 810 820 830 840
830 840
pF1KB4 LLQPSHYGQSGISMSHMDLRANPSW
:::::::::::::::::::::::::
XP_011 LLQPSHYGQSGISMSHMDLRANPSW
850 860
847 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:39:37 2016 done: Thu Nov 3 15:39:39 2016
Total Scan time: 13.840 Total Display time: 0.310
Function used was FASTA [36.3.4 Apr, 2011]