Result of FASTA (ccds) for
pF1KB4872
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4872, 2944 aa
1>>>pF1KB4872 2944 - 2944 aa - 2944 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 12.0629+/-0.00155; mu= 2.7071+/- 0.094
mean_var=748.7976+/-152.265, 0's: 0 Z-trim(112.9): 281 B-trim: 0 in 0/52
Lambda= 0.046870
statistics sampled from 13326 (13596) to 13326 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.418), width: 16
Scan time: 8.660
The best scores are: opt bits E(32554)
CCDS2773.1 COL7A1 gene_id:1294|Hs108|chr3 (2944) 20871 1429.7 0
CCDS42828.1 COL4A4 gene_id:1286|Hs108|chr2 (1690) 3566 259.2 1.5e-67
CCDS76010.1 COL4A6 gene_id:1288|Hs108|chrX (1707) 3398 247.9 4e-64
CCDS41778.1 COL2A1 gene_id:1280|Hs108|chr12 (1487) 3287 240.3 6.7e-62
CCDS8759.1 COL2A1 gene_id:1280|Hs108|chr12 (1418) 3277 239.6 1e-61
CCDS9511.1 COL4A1 gene_id:1282|Hs108|chr13 (1669) 3261 238.6 2.4e-61
CCDS6982.1 COL5A1 gene_id:1289|Hs108|chr9 (1838) 3197 234.3 5.1e-60
CCDS75932.1 COL5A1 gene_id:1289|Hs108|chr9 (1838) 3197 234.3 5.1e-60
CCDS41907.1 COL4A2 gene_id:1284|Hs108|chr13 (1712) 3191 233.9 6.5e-60
CCDS14542.1 COL4A6 gene_id:1288|Hs108|chrX (1690) 3161 231.8 2.6e-59
CCDS14541.1 COL4A6 gene_id:1288|Hs108|chrX (1691) 3161 231.8 2.6e-59
CCDS76009.1 COL4A6 gene_id:1288|Hs108|chrX (1666) 3130 229.7 1.1e-58
CCDS53348.1 COL11A1 gene_id:1301|Hs108|chr1 (1767) 3057 224.8 3.5e-57
CCDS778.1 COL11A1 gene_id:1301|Hs108|chr1 (1806) 3057 224.8 3.6e-57
CCDS780.2 COL11A1 gene_id:1301|Hs108|chr1 (1690) 3041 223.7 7.3e-57
CCDS76008.1 COL4A6 gene_id:1288|Hs108|chrX (1633) 3039 223.6 7.8e-57
CCDS6376.1 COL22A1 gene_id:169044|Hs108|chr8 (1626) 2900 214.2 5.3e-54
CCDS2297.1 COL3A1 gene_id:1281|Hs108|chr2 (1466) 2862 211.5 3e-53
CCDS12222.1 COL5A3 gene_id:50509|Hs108|chr19 (1745) 2864 211.8 3e-53
CCDS35366.1 COL4A5 gene_id:1287|Hs108|chrX (1691) 2702 200.8 5.8e-50
CCDS42829.1 COL4A3 gene_id:1285|Hs108|chr2 (1670) 2699 200.6 6.6e-50
CCDS33350.1 COL5A2 gene_id:1290|Hs108|chr2 (1499) 2632 196.0 1.4e-48
CCDS14543.1 COL4A5 gene_id:1287|Hs108|chrX (1685) 2595 193.6 8.7e-48
CCDS43452.1 COL11A2 gene_id:1302|Hs108|chr6 (1650) 2494 186.7 9.8e-46
CCDS34682.1 COL1A2 gene_id:1278|Hs108|chr7 (1366) 2350 176.9 7.5e-43
CCDS11561.1 COL1A1 gene_id:1277|Hs108|chr17 (1464) 2227 168.6 2.5e-40
CCDS41297.1 COL16A1 gene_id:1307|Hs108|chr1 (1604) 2084 159.0 2.1e-37
CCDS6802.1 COL27A1 gene_id:85301|Hs108|chr9 (1860) 2084 159.1 2.3e-37
CCDS4970.1 COL19A1 gene_id:1310|Hs108|chr6 (1142) 1986 152.1 1.7e-35
CCDS41353.1 COL24A1 gene_id:255631|Hs108|chr1 (1714) 1875 144.9 4e-33
CCDS450.1 COL9A2 gene_id:1298|Hs108|chr1 ( 689) 1750 135.9 8.3e-31
CCDS4971.1 COL9A1 gene_id:1297|Hs108|chr6 ( 921) 1727 134.5 2.9e-30
CCDS47447.1 COL9A1 gene_id:1297|Hs108|chr6 ( 678) 1723 134.0 2.9e-30
CCDS42971.1 COL18A1 gene_id:80781|Hs108|chr21 (1339) 1700 132.9 1.3e-29
CCDS42972.1 COL18A1 gene_id:80781|Hs108|chr21 (1519) 1700 133.0 1.4e-29
CCDS77643.1 COL18A1 gene_id:80781|Hs108|chr21 (1754) 1700 133.1 1.5e-29
CCDS44419.1 COL13A1 gene_id:1305|Hs108|chr10 ( 717) 1540 121.7 1.6e-26
CCDS43258.1 COL25A1 gene_id:84570|Hs108|chr4 ( 654) 1460 116.2 6.5e-25
CCDS13505.1 COL9A3 gene_id:1299|Hs108|chr20 ( 684) 1436 114.6 2e-24
CCDS43553.1 COL28A1 gene_id:340267|Hs108|chr7 (1125) 1442 115.3 2e-24
CCDS5105.1 COL10A1 gene_id:1300|Hs108|chr6 ( 680) 1430 114.2 2.7e-24
CCDS44424.2 COL13A1 gene_id:1305|Hs108|chr10 ( 695) 1406 112.6 8.4e-24
CCDS43259.1 COL25A1 gene_id:84570|Hs108|chr4 ( 642) 1380 110.8 2.7e-23
CCDS44427.2 COL13A1 gene_id:1305|Hs108|chr10 ( 645) 1372 110.3 4e-23
CCDS44425.2 COL13A1 gene_id:1305|Hs108|chr10 ( 686) 1362 109.6 6.6e-23
CCDS2934.1 COL8A1 gene_id:1295|Hs108|chr3 ( 744) 1362 109.7 6.9e-23
CCDS58922.1 COL25A1 gene_id:84570|Hs108|chr4 ( 645) 1349 108.7 1.2e-22
CCDS403.1 COL8A2 gene_id:1296|Hs108|chr1 ( 703) 1349 108.8 1.2e-22
CCDS44423.2 COL13A1 gene_id:1305|Hs108|chr10 ( 668) 1338 108.0 2e-22
CCDS72756.1 COL8A2 gene_id:1296|Hs108|chr1 ( 638) 1289 104.6 1.9e-21
>>CCDS2773.1 COL7A1 gene_id:1294|Hs108|chr3 (2944 aa)
initn: 20871 init1: 20871 opt: 20871 Z-score: 7647.7 bits: 1429.7 E(32554): 0
Smith-Waterman score: 20871; 100.0% identity (100.0% similar) in 2944 aa overlap (1-2944:1-2944)
10 20 30 40 50 60
pF1KB4 MTLRLLVAALCAGILAEAPRVRAQHRERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 MTLRLLVAALCAGILAEAPRVRAQHRERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 LEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 LEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 AAILHVADHVFLPQLARPGVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 AAILHVADHVFLPQLARPGVPKVCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EELKRVASQPTSDFFFFVNDFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 EELKRVASQPTSDFFFFVNDFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 SEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGATGYRVTW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 TEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGATGYRVTW
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 RVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 RVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 LRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 LRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 RLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGATQYRII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 RLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGATQYRII
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 VRSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 VRSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 VPGLRVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLPPDSTATDITGLQPGTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 VPGLRVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLPPDSTATDITGLQPGTT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 YQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 YQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWH
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 SAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 SAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVS
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 RLQILNASSDVLRITWVGVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 RLQILNASSDVLRITWVGVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSY
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 SVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQGFLLHW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 SVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQGFLLHW
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 QPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 QPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSI
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 ELRVVDTSIDSVTLAWTPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 ELRVVDTSIDSVTLAWTPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 GVSYIFSLTPVLDGVRGPEASVTQTPVCPRGLADVVFLPHATQDNAHRAEATRRVLERLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 GVSYIFSLTPVLDGVRGPEASVTQTPVCPRGLADVVFLPHATQDNAHRAEATRRVLERLV
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB4 LALGPLGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 LALGPLGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVT
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB4 AHRYMLAPDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 AHRYMLAPDAPGRRQHVPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQL
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KB4 RRLAPGMDSVQTFFAVDDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 RRLAPGMDSVQTFFAVDDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPG
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KB4 EMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 EMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPG
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KB4 APGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 APGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRG
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420 1430 1440
pF1KB4 PLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 PLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGP
1390 1400 1410 1420 1430 1440
1450 1460 1470 1480 1490 1500
pF1KB4 PGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 PGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPP
1450 1460 1470 1480 1490 1500
1510 1520 1530 1540 1550 1560
pF1KB4 GPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 GPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVG
1510 1520 1530 1540 1550 1560
1570 1580 1590 1600 1610 1620
pF1KB4 PAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 PAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGR
1570 1580 1590 1600 1610 1620
1630 1640 1650 1660 1670 1680
pF1KB4 PGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 PGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGE
1630 1640 1650 1660 1670 1680
1690 1700 1710 1720 1730 1740
pF1KB4 DGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 DGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPG
1690 1700 1710 1720 1730 1740
1750 1760 1770 1780 1790 1800
pF1KB4 APGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 APGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAG
1750 1760 1770 1780 1790 1800
1810 1820 1830 1840 1850 1860
pF1KB4 KAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 KAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKG
1810 1820 1830 1840 1850 1860
1870 1880 1890 1900 1910 1920
pF1KB4 DSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 DSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGS
1870 1880 1890 1900 1910 1920
1930 1940 1950 1960 1970 1980
pF1KB4 KGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 KGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGP
1930 1940 1950 1960 1970 1980
1990 2000 2010 2020 2030 2040
pF1KB4 KGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 KGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPG
1990 2000 2010 2020 2030 2040
2050 2060 2070 2080 2090 2100
pF1KB4 IPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 IPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPG
2050 2060 2070 2080 2090 2100
2110 2120 2130 2140 2150 2160
pF1KB4 PGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 PGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGM
2110 2120 2130 2140 2150 2160
2170 2180 2190 2200 2210 2220
pF1KB4 AGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 AGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLT
2170 2180 2190 2200 2210 2220
2230 2240 2250 2260 2270 2280
pF1KB4 GPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 GPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSP
2230 2240 2250 2260 2270 2280
2290 2300 2310 2320 2330 2340
pF1KB4 GLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 GLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGE
2290 2300 2310 2320 2330 2340
2350 2360 2370 2380 2390 2400
pF1KB4 KGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 KGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAP
2350 2360 2370 2380 2390 2400
2410 2420 2430 2440 2450 2460
pF1KB4 GVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 GVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDK
2410 2420 2430 2440 2450 2460
2470 2480 2490 2500 2510 2520
pF1KB4 GDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 GDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKG
2470 2480 2490 2500 2510 2520
2530 2540 2550 2560 2570 2580
pF1KB4 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR
2530 2540 2550 2560 2570 2580
2590 2600 2610 2620 2630 2640
pF1KB4 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEK
2590 2600 2610 2620 2630 2640
2650 2660 2670 2680 2690 2700
pF1KB4 GDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 GDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEK
2650 2660 2670 2680 2690 2700
2710 2720 2730 2740 2750 2760
pF1KB4 GERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 GERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPG
2710 2720 2730 2740 2750 2760
2770 2780 2790 2800 2810 2820
pF1KB4 APGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 APGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYA
2770 2780 2790 2800 2810 2820
2830 2840 2850 2860 2870 2880
pF1KB4 ADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEAPWDSDDPCSLPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 ADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEAPWDSDDPCSLPL
2830 2840 2850 2860 2870 2880
2890 2900 2910 2920 2930 2940
pF1KB4 DEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRCPPRVVQSQGTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS27 DEGSCTAYTLRWYHRAVTGSTEACHPFVYGGCGGNANRFGTREACERRCPPRVVQSQGTG
2890 2900 2910 2920 2930 2940
pF1KB4 TAQD
::::
CCDS27 TAQD
>>CCDS42828.1 COL4A4 gene_id:1286|Hs108|chr2 (1690 aa)
initn: 1716 init1: 915 opt: 3566 Z-score: 1326.2 bits: 259.2 E(32554): 1.5e-67
Smith-Waterman score: 3909; 43.1% identity (53.8% similar) in 1591 aa overlap (1261-2800:60-1473)
1240 1250 1260 1270 1280 1290
pF1KB4 TALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPG
: : :: :::: : : ::::: : :
CCDS42 LFSVQYVYGSGKKYIGPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSG
30 40 50 60 70 80
1300 1310 1320 1330 1340 1350
pF1KB4 SATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPG
.:.:: ::: : :. : .: :: :: :. : :: ::::: :: : : .:.::
CCDS42 EKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPG
90 100 110 120 130 140
1360 1370 1380 1390 1400 1410
pF1KB4 APGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGP
:: :: : :: :::: :: .: : . . :: .:.::
CCDS42 FPG-----------GR-------GALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRG-
150 160 170 180 190
1420 1430 1440 1450 1460 1470
pF1KB4 PGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPR
.::::::::: : ::.:: : :: ::: : ::.::. : .
CCDS42 -----------DPGLPGLPGSWGAGGPAGPTGYPGE--------PGLVGPPGQPGRPGLK
200 210 220 230
1480 1490 1500 1510 1520
pF1KB4 GPPGAIGPKGDRGFPGPLGEAGEKGER---GPPGPAGSRGLPGVAGRPGAKGPEGPPGPT
: :: .: ::. : :: .:. : : :: .: :. : :: : ::::
CCDS42 GNPG-VGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRK
240 250 260 270 280 290
1530 1540 1550 1560 1570 1580
pF1KB4 GRQG--EKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDP
:..: ::: : :: : ::.:. :. : : : : : : ::: :
CCDS42 GESGIGAKGEKGIPGFP--------GPRGDPGSYGSPGFPGLKGELGLVGDPGLF--GLI
300 310 320 330 340
1590 1600 1610 1620 1630
pF1KB4 GPKGDPGDRGPIGLTGR--------AGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEV-
:::::::.:: : : ::::: : ::. :. : ::::: : :: ::.
CCDS42 GPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEAC
350 360 370 380 390 400
1640 1650 1660 1670 1680 1690
pF1KB4 -GEKGDEGPPGDPGLPGKAGERGLRGAP-GVRGPVGEKGDQGDPGEDGRNGSPGSSGPKG
: : :: : ::::: :: :. : : .. : :. :. : :: : .: ::::
CCDS42 AGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYC
410 420 430 440 450 460
1700 1710 1720 1730 1740
pF1KB4 DRGEPGPPGPPGRLVDTGPGAR-EKGEPGDRG----QEGPRGPKGDPGLPGAPGERGIEG
. :.::: : :.. ::.: ::: :..: . :: :: : ::::: : .:
CCDS42 SVGNPGPQGIKGKV--GPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKG---
470 480 490 500 510
1750 1760 1770 1780 1790 1800
pF1KB4 FRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDG
: :. : : ::: :::: .: :: :: ::.:: : .:: :: .
CCDS42 ---------DLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGA---KGDMVVSR
520 530 540 550 560
1810 1820 1830 1840 1850 1860
pF1KB4 LPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREG
. : .::.: :.::::.::.:: :. : :..:.:: ::.
CCDS42 VKGHKGERG---PDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDH----------------
570 580 590 600
1870 1880 1890 1900 1910 1920
pF1KB4 RDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGE
.:. : .: :: : :::: ::::::: ::: :: :.::. : :. :. :
CCDS42 EDATPGGKGFPG---PLGPPGKAGPVGPPGLGFP------GPPGERGHPGVPGHPGVRGP
610 620 630 640 650
1930 1940 1950 1960 1970 1980
pF1KB4 RGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGP
::.:. :.. . . . : :..::
CCDS42 DGLKGQKGDTISCN---------------------------VTYP----------GRHGP
660 670
1990 2000 2010 2020 2030 2040
pF1KB4 PGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAG
:: .:: :: .:. ::::: :::. : .: :.:: :: .:: :
CCDS42 PGFDGP---PGPKGF------PGPQGAPGLS-------GSDGHKGRPGTPGTAEIPGPPG
680 690 700 710 720
2050 2060 2070 2080 2090 2100
pF1KB4 GVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGP
:. : :: ::.: . : :::: ::. : : :: . :: : .:
CCDS42 FRGDMGDPGFGGEKGSS----PVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGV
730 740 750 760 770
2110 2120 2130 2140 2150 2160
pF1KB4 PGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPG---ERGMAGPEGK
::.:: .:.:: : .:: : : :.:: .:. : : : :: :: ::: : :.
CCDS42 PGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQ
780 790 800 810 820 830
2170 2180 2190 2200 2210 2220
pF1KB4 PGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGR-GLTGPTGA
::: : : :: ::.:.:: : :: ::: .: :: :.:: :::: :. :: :
CCDS42 PGLPGYPGSPGAPGGKGQPGDVGPPG---PAGMKGLPGLPGRPGAHGPPGLPGIPGPFGD
840 850 860 870 880 890
2230 2240 2250 2260 2270 2280
pF1KB4 VGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGP
::::::::.: :.: ::.:: :: ::::: : ::.:. :..: :.::. :: :
CCDS42 DGLPGPPGPKG---PRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGA
900 910 920 930 940 950
2290 2300 2310 2320 2330 2340
pF1KB4 VGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAG
: : :: : .:... :. :: : :: : : :: .::.: :: .:..:: :
CCDS42 KGAIGPPGDEGE--MAIISQKGTPGEPGPPGD---D--GFPGERGDKGTPGMQGRRGEPG
960 970 980 990 1000
2350 2360 2370 2380 2390 2400
pF1KB4 RAGEPG-DPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVG
: : :: :: :.:: ::: : : :: : : : ::. :: : :: :: :: :
CCDS42 RYGPPGFHRGEPGEKGQPGPPGPPGPPGS--TGLRGFIGFPGLPGDQGEPGSPGPPGFSG
1010 1020 1030 1040 1050 1060
2410 2420 2430 2440 2450
pF1KB4 FPGQTGPRGEMGQP----GPSGERGLAGPPG---------REGIPGPLGPPGPPGSVGPP
. : ::.:. :.: :: : .: : :: ..:.:: :: : :: :::
CCDS42 IDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPP
1070 1080 1090 1100 1110 1120
2460 2470 2480 2490 2500 2510
pF1KB4 GASGLKGDKGDPGV-GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDV
:.:: : :: :. :: : :: :.:: :: .: :: :: :. :: :: : : .:
CCDS42 GSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLK
1130 1140 1150 1160 1170 1180
2520 2530 2540 2550 2560
pF1KB4 GSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDG--DKGPRGDNGDPGDKGSKGEP
:. : :: .: : ::::: : : :::: : : :::: .: :: ::.: :
CCDS42 GQKGTKGASGLHDV--GPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPP
1190 1200 1210 1220 1230 1240
2570 2580 2590 2600 2610 2620
pF1KB4 GDKGSAGL-------PGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGP
: :..: :: : :: : : : :: :: :: .: .::: :: :. ::
CCDS42 GPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPG--SVDLLRGEPGDCGLPGP
1250 1260 1270 1280 1290
2630 2640 2650 2660 2670 2680
pF1KB4 RGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGP
: : : : :. : : :. :: : :: .: : :: ::..: :: : ::
CCDS42 PGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPG---PQGPHGFPGPPGEKGLPGPPGRKGP
1300 1310 1320 1330 1340 1350
2690 2700 2710 2720 2730
pF1KB4 KGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGP--RGPEGLQ
: : :.::: .: . . ::. : :: : .:. : :: : :: .: ::.
CCDS42 TGLPGPRGEPGPPADVDDCPR--IPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLD
1360 1370 1380 1390 1400 1410
2740 2750 2760 2770 2780 2790
pF1KB4 GQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMS
:..: : :: : :: : :: : : ::: :: :. : .. . ::. :
CCDS42 GRRGVDGVPGS--PGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLGGFLLVLHS
1420 1430 1440 1450 1460 1470
2800 2810 2820 2830 2840 2850
pF1KB4 QHCACQGQFIASGSRPLPSYAADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYS
:
CCDS42 QTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCH
1480 1490 1500 1510 1520 1530
>>CCDS76010.1 COL4A6 gene_id:1288|Hs108|chrX (1707 aa)
initn: 1911 init1: 978 opt: 3398 Z-score: 1264.8 bits: 247.9 E(32554): 4e-64
Smith-Waterman score: 3668; 42.9% identity (54.4% similar) in 1589 aa overlap (1247-2769:39-1483)
1220 1230 1240 1250 1260 1270
pF1KB4 DDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGL
: . :: .:.:: .:..: .:: : .
CCDS76 LVTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQG---F
10 20 30 40 50 60
1280 1290 1300 1310 1320 1330
pF1KB4 PGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGD
: :: : :::::::: : : .: :. : :.::. : :.::
CCDS76 TGSTGLSG---------LKGERGFPGLLG-PYGP--KGDKGPMGVPGFLGINGIPG---H
70 80 90 100 110
1340 1350 1360 1370 1380 1390
pF1KB4 PGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGT
::. ::::: ::: : .: : : ::: : :: :::::::
CCDS76 PGQPGPRGP---------------PGLDGCNGTQGAVGFPGPD---GYPGLLGPPGLPG-
120 130 140 150
1400 1410 1420 1430 1440 1450
pF1KB4 AMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPG
.::.::: :: .: :.:::::: : :::: .: : ::
CCDS76 -QKGSKGD--PVLAPGSFKG--MKGDPGLPGLDGITGPQG--AP------------GFPG
160 170 180 190
1460 1470 1480 1490 1500 1510
pF1KB4 LPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAG---SRGLPGVAG
: : :: ::: :::: .:: :. :. : :: : ::. : ::::: : : :
CCDS76 AVGPAGPPGLQGPPGPPGPLGPDGNMGL-GFQGEKGVKGDVGLPGPAGPPPSTGELEFMG
200 210 220 230 240 250
1520 1530 1540 1550 1560 1570
pF1KB4 RP-GAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQG
: : :: .: ::: : : .: :: :: ...: : ::::: : :::: : .:
CCDS76 FPKGKKGSKGEPGPKGFPGISGPPGFPGL-GTTGEK--GEKGEKGIPGLPGPRGPMGSEG
260 270 280 290 300
1580 1590 1600 1610 1620
pF1KB4 ERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPP------GE--KGDPGRPGPP
.:::: : : : :: : :. :. : : :: : .:.:: :: :
CCDS76 VQGPPGQ--QGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVP
310 320 330 340 350 360
1630 1640 1650 1660 1670 1680
pF1KB4 GPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRN
: : .: .: : .: : :: :.: : : : .: ::. :::::.::.
CCDS76 GLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGL------KGDQGNPGRT-TI
370 380 390 400 410
1690 1700 1710 1720 1730
pF1KB4 GSPGSSGPKGDRGEPGPPGPPGRLVDTGP-GAREKGEPGDRGQEGPRGP------KGDPG
:. : : : : :::::::. .: .:.: :: ::..::.: ::: :
CCDS76 GAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSG
420 430 440 450 460 470
1740 1750 1760 1770 1780 1790
pF1KB4 L----PGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPS
. :.:. : : ::::: : :. : : .:::: : .: .: :: .::
CCDS76 FCACDGGVPNT-GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAG---APGLVGPL
480 490 500 510 520 530
1800 1810 1820 1830 1840 1850
pF1KB4 GPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED
::.: :: :.: . . :. :..: : .: :. :.::.:: ::: : : ::: :.
CCDS76 GPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-
540 550 560 570 580 590
1860 1870 1880 1890 1900 1910
pF1KB4 GRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKG
: :::: : : ::.: :: :::::: .:.::.:: : :
CCDS76 GFPGEKGLPGL--------P-GEKGHPG------PPGLPG------NGLPGLPGPRGLPG
600 610 620 630
1920 1930 1940 1950 1960 1970
pF1KB4 DRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVE-TWDESSGSFLP
:.:. : :.::::: .: : ::. . : : ::
CCDS76 DKGKDGLPGQQGLPGSKG-----------D----------CCCREVGKGDLDTERGITLP
640 650 660 670
1980 1990 2000 2010 2020
pF1KB4 --VPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLA-LGER-GPPG
.: ::.: : : :: .: :.:: : :. :. : : :::. : : : ::
CCDS76 CIIPGSY-GPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPG
680 690 700 710 720 730
2030 2040 2050 2060 2070 2080
pF1KB4 PSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERG-----EKGERGEQGRDGPPGLPGT
: : : :: ::.:: : : .: : :: .: : :.: :::: .: : :
CCDS76 PRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGF
740 750 760 770 780 790
2090 2100 2110 2120 2130 2140
pF1KB4 PGPPGPPGPKVSVDEPGP-GLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGE
: : :: : .:: : .::.: :: : :.::. :..:: : .: :. : :
CCDS76 LGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGF
800 810 820 830 840 850
2150 2160 2170 2180 2190
pF1KB4 PGPRGQDGNPGLPGERGMAGPEG---KPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGP
: : .:.:: : :: :: : : :: : .: :: : : : ::.::.:: .
CCDS76 P---GISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPAL
860 870 880 890 900
2200 2210 2220 2230 2240 2250
pF1KB4 QGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGA
.::.: :: : .: :: :: : :. :: : :: .: .::.: : ::. :. :.::
CCDS76 SGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGP
910 920 930 940 950 960
2260 2270 2280 2290 2300 2310
pF1KB4 PG----RDGASGK--DGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEK
: : :. ::.:: : :: :.::: : ::: : : :: :::: :
CCDS76 VGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPG-----LPGAPGLP
970 980 990 1000 1010 1020
2320 2330 2340 2350 2360
pF1KB4 GAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPG-P-----KG
: :..: : :: : ::::: .: .: .: : ::. : .: .:.:: : :
CCDS76 GIIKGVSGK-PGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPG
1030 1040 1050 1060 1070 1080
2370 2380 2390 2400 2410 2420
pF1KB4 FKGDPG--VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGER
.::: : : . ::::: : :: .: : : : : .::::. .:: :. : ::.
CCDS76 LKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGN---KGEDGKVGVSGDV
1090 1100 1110 1120 1130
2430 2440 2450 2460 2470 2480
pF1KB4 GLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDG
:: : :: :. : : :: ::: : :: : :.: :: ::.: : ::..: .:
CCDS76 GLPGAPGFPGVAGMRGEPGLPGSSGHQGA---IGPLGSP--GLIGPKGFPGFPGLHGLNG
1140 1150 1160 1170 1180 1190
2490 2500 2510 2520 2530 2540
pF1KB4 RPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPR
:: .: .: :: . : : .: : ::.:: .. .: :: : .: ..: :
CCDS76 LPGTKGTHGTPGPSIT----GVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRG---QKGDR
1200 1210 1220 1230 1240
2550 2560 2570 2580 2590
pF1KB4 GLDGDKGPRGDNGDPGDKGSK---GEPGDKGSAGLPGLRGLLGPQGQPGAAGIP----GD
:. : .:: : : :: . . :.::: : :: : :: :: : :: : : ::
CCDS76 GFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPG-PSSNQGD
1250 1260 1270 1280 1290 1300
2600 2610 2620 2630 2640 2650
pF1KB4 PGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGH
:.:: :.:: .: ::: :. : :: :: :.:: : : : :..:::: ::. :
CCDS76 TGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGM
1310 1320 1330 1340 1350 1360
2660 2670 2680 2690 2700 2710
pF1KB4 KGEMGEPGVPGQSGAPGKEGLI-------GPKGDRGFDGQPGPKGDQGEKGERGTPGIGG
::. : : : .: ::. :: : :.:: :: :: : .: : : :
CCDS76 KGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKG
1370 1380 1390 1400 1410 1420
2720 2730 2740 2750 2760 2770
pF1KB4 FPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGR
.:: :.:: .: :::::..: : :::: : .: ::.. : :.:: ::. . :
CCDS76 LPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQ--GPFGMPGMPGQSMRVGY
1430 1440 1450 1460 1470 1480
2780 2790 2800 2810 2820 2830
pF1KB4 PGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYAADTAGSQLHA
CCDS76 TLVKHSQSEQVPPCPIGMSQLWVGYSLLFVEGQEKAHNQDLGFAGSCLPRFSTMPFIYCN
1490 1500 1510 1520 1530 1540
>>CCDS41778.1 COL2A1 gene_id:1280|Hs108|chr12 (1487 aa)
initn: 2804 init1: 1049 opt: 3287 Z-score: 1224.8 bits: 240.3 E(32554): 6.7e-62
Smith-Waterman score: 3508; 44.5% identity (55.1% similar) in 1381 aa overlap (1342-2685:78-1276)
1320 1330 1340 1350 1360
pF1KB4 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGE--PGAPGQVIGGEG-PGLPGRKG
:. : :: : : .. . : :: :.::
CCDS41 KPEPCRICVCDTGTVLCDDIICEDVKDCLSPEIPFGECCPICPTDLATASGQPGPKGQKG
50 60 70 80 90 100
1370 1380 1390 1400 1410 1420
pF1KB4 DPG-------PSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPG
.:: :.:::::.:: :. :::: :.::.::.: ::: .: :
CCDS41 EPGDIKDIVGPKGPPGPQGPAGEQGPRG-----------DRGDKGEKGAPGP-RG--RDG
110 120 130 140 150
1430 1440 1450 1460 1470
pF1KB4 EPGLPGLPGSPGPQGPVGPPGKKGE-----KG--DSEDGAPGLPGQPGSPGEQGPRGPPG
::: :: :: ::: :: :::: :. : : . :. : . : : .:::::::
CCDS41 EPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG
160 170 180 190 200 210
1480 1490 1500 1510 1520
pF1KB4 AIGPKGDRGFPGPLGEAGEKG------ERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTG
: : .:: : :: :: : :::::: :. : : ::.:: : .:::::
CCDS41 PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP--
220 230 240 250 260 270
1530 1540 1550 1560 1570 1580
pF1KB4 RQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLV-LPGDPGP
:: .: :: :: :.: : .: : : : :: ::.:: : :: :: ::
CCDS41 -QGARGFPGTPG-----LPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP
280 290 300 310 320
1590 1600 1610 1620 1630 1640
pF1KB4 KGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGD
.: ::.:: :.:: : .: :. :.:: :::::::: : : ::
CCDS41 RGLPGERG------RTGPAGAAGARGNDGQPGPAGPPGPVGP---------AGGPGFPGA
330 340 350 360 370
1650 1660 1670 1680 1690 1700
pF1KB4 PGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR
:: :.:: : :: :..:: :: : :.:: : .:.::..: : .: : :: :
CCDS41 PGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG-
380 390 400 410 420
1710 1720 1730 1740 1750 1760
pF1KB4 LVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAG
. :: : : :: .: :: ::::. : :: : ::.: ::.:.:: :::
CCDS41 -APGFPGPR--GPPGPQGATGPLGPKGQTGEPG------IAGFKGEQGPKGEPG---PAG
430 440 450 460 470
1770 1780 1790 1800 1810 1820
pF1KB4 EKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPG
.: :: : .:. : :.::..:: :: ::. : :: :: : : .:: :
CCDS41 PQGAPGPAGEEGKRGARGEPGGVGPIGP---------PGERGAPGNRGFPGQDGLAGPKG
480 490 500 510 520
1830 1840 1850 1860 1870 1880
pF1KB4 LPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQG
::. : .: : .: ::.:: ::: : : .: .:: : ::.:. : : : .:
CCDS41 APGERGPSGLAGPKGANGDPGRPGEPGLPGARG---LTGRPGDAGPQGKVGPSGAPGEDG
530 540 550 560 570 580
1890 1900 1910 1920 1930 1940
pF1KB4 PPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLE
:: ::: : :: ::: : :::: :: :. ::.:::: :::: ::.
CCDS41 RPGPPGPQGARGQ--PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGK---------
590 600 610 620 630
1950 1960 1970 1980 1990 2000
pF1KB4 TAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGD
:..: :::: :: : ::: .
CCDS41 ---------------------------------DGETGAAGPPGPAGPAG---ERG---E
640 650
2010 2020 2030 2040 2050 2060
pF1KB4 RGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKG
.: :::.: :: ::::: :: :::: :.::.::. : .: :::: ::.:
CCDS41 QGAPGPSGFQGLP----GPPGPP---GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERG
660 670 680 690 700
2070 2080 2090 2100 2110 2120
pF1KB4 ERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGP-GLSGEQGPPGLKGAKGEPGSNGDQG
: :: .:: ::::::: :: : . :: : : ::::::.: :: :. : :
CCDS41 SPGAQGLQGPRGLPGTPGTDGPKGAS------GPAGPPGAQGPPGLQGMPGERGAAGIAG
710 720 730 740 750 760
2130 2140 2150 2160 2170 2180
pF1KB4 PKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPG
:::::: : :: :: .: :: : :: : :: :::::.:..:. :
CCDS41 PKGDRG------DVGEKGP---EGAPGKDGGRG---------LTGPIGPPGPAGANGEKG
770 780 790 800
2190 2200 2210 2220 2230 2240
pF1KB4 PPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPG
: :: ::: : : :: ::::::: :..:: :: : :: : .: .: .:. :
CCDS41 EVGPPG---PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG
810 820 830 840 850 860
2250 2260 2270 2280 2290 2300
pF1KB4 LPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGL
:: : .: :: : :..: : ::. : ::. :.:: .: : :: .: :: :
CCDS41 APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP--GP
870 880 890 900 910
2310 2320 2330 2340 2350 2360
pF1KB4 PGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPK
:: .:. : : : :: : :: :. :: :: : :: ::::: : .: .: :::.
CCDS41 PGPSGKDG-PKGARGD-SGPPGRAGEPGLQGPAGPPGE---KGEPGDDGPSGAEGPPGPQ
920 930 940 950 960 970
2370 2380 2390 2400 2410 2420
pF1KB4 GFKGDPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGER
:. :. : ::.::. : : : :::: : :: : :: .: :: : :: :
CCDS41 GLAGQRGIVGLPGQRGERGFP------GLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT
980 990 1000 1010 1020
2430 2440 2450 2460 2470 2480
pF1KB4 GLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV----GLPGPRGERGEPGIR
: :: ::::: :: :::: :..: : : : : ::. : ::: : :. : :
CCDS41 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR
1030 1040 1050 1060 1070 1080
2490 2500 2510 2520 2530
pF1KB4 GEDGRPGQEGP------RGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGA
:: : : :: ::. :: : ::..:: :. : :::: .: .. . : ::: :
CCDS41 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG-LQGLPGPPGP
1090 1100 1110 1120 1130 1140
2540 2550 2560 2570 2580 2590
pF1KB4 KGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGI
.::.: :: : .: .:: : : : :..: :: : : : : :: : :: :
CCDS41 SGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGP
1150 1160 1170 1180 1190 1200
2600 2610 2620 2630 2640 2650
pF1KB4 PGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGL
:: :: :: ::: . . . .::: :: :. ..:.. :: ::
CCDS41 PGPPGPPG----PGI--DMSAFAGLGPRE-------KGPDPLQYMRADQA-AG-----GL
1210 1220 1230 1240
2660 2670 2680 2690 2700 2710
pF1KB4 AGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGP
: .:. . .: :.. .:.:.:
CCDS41 RQHDAEV---DATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQG
1250 1260 1270 1280 1290 1300
2720 2730 2740 2750 2760 2770
pF1KB4 SGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPA
CCDS41 CTLDAMKVFCNMETGETCVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDN
1310 1320 1330 1340 1350 1360
>>CCDS8759.1 COL2A1 gene_id:1280|Hs108|chr12 (1418 aa)
initn: 2804 init1: 1049 opt: 3277 Z-score: 1221.4 bits: 239.6 E(32554): 1e-61
Smith-Waterman score: 3497; 44.5% identity (55.0% similar) in 1373 aa overlap (1340-2685:29-1207)
1310 1320 1330 1340 1350 1360
pF1KB4 PGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGD
: : ::::. : ::.. :
CCDS87 MIRLGAPQTLVLLTLLVAAVLRCQGQDVRQP-GPKGQKGEPGDI-----------KDI
10 20 30 40
1370 1380 1390 1400 1410 1420
pF1KB4 PGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLP
::.:::::.:: :. :::: :.::.::.: ::: .: :::: :: :
CCDS87 VGPKGPPGPQGPAGEQGPRG-----------DRGDKGEKGAPGP-RG--RDGEPGTPGNP
50 60 70 80 90
1430 1440 1450 1460 1470 1480
pF1KB4 GSPGPQGPVGPPGKKGE-----KG--DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDR
: ::: :: :::: :. : : . :. : . : : .::::::: : : .
CCDS87 GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQ
100 110 120 130 140 150
1490 1500 1510 1520 1530
pF1KB4 GFPGPLGEAGEKG------ERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEP
:: : :: :: : :::::: :. : : ::.:: : .::::: :: .: :
CCDS87 GFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP---QGARGFP
160 170 180 190 200
1540 1550 1560 1570 1580 1590
pF1KB4 GRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLV-LPGDPGPKGDPGDRG
: :: :.: : .: : : : :: ::.:: : :: :: ::.: ::.::
CCDS87 GTPGLPGV-----KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERG
210 220 230 240 250 260
1600 1610 1620 1630 1640 1650
pF1KB4 PIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAG
:.:: : .: :. :.:: :::::::: : : :: :: :.::
CCDS87 ------RTGPAGAAGARGNDGQPGPAGPPGPVGP---------AGGPGFPGAPGAKGEAG
270 280 290 300
1660 1670 1680 1690 1700 1710
pF1KB4 ERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGA
: :: :..:: :: : :.:: : .:.::..: : .: : :: : . ::
CCDS87 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG--APGFPGP
310 320 330 340 350 360
1720 1730 1740 1750 1760 1770
pF1KB4 REKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPP
: : :: .: :: ::::. : :: : ::.: ::.:.:: ::: .: ::
CCDS87 R--GPPGPQGATGPLGPKGQTGEPG------IAGFKGEQGPKGEPG---PAGPQGAPGPA
370 380 390 400 410
1780 1790 1800 1810 1820 1830
pF1KB4 GLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGED
: .:. : :.::..:: :: ::. : :: :: : : .:: : ::. : .
CCDS87 GEEGKRGARGEPGGVGPIGP---------PGERGAPGNRGFPGQDGLAGPKGAPGERGPS
420 430 440 450 460
1840 1850 1860 1870 1880 1890
pF1KB4 GKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPV
: : .: ::.:: ::: : : .: .:: : ::.:. : : : .: :: :::
CCDS87 GLAGPKGANGDPGRPGEPGLPGARG---LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ
470 480 490 500 510 520
1900 1910 1920 1930 1940 1950
pF1KB4 GPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASA
: :: ::: : :::: :: :. ::.:::: :::: ::.
CCDS87 GARGQ--PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGK-----------------
530 540 550 560
1960 1970 1980 1990 2000 2010
pF1KB4 LREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQG
:..: :::: :: : ::: ..: :::.:
CCDS87 -------------------------DGETGAAGPPGPAGPAG---ERG---EQGAPGPSG
570 580 590
2020 2030 2040 2050 2060 2070
pF1KB4 PPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRD
:: ::::: :: :::: :.::.::. : .: :::: ::.: : :: .
CCDS87 FQGLP----GPPGP---PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ
600 610 620 630 640
2080 2090 2100 2110 2120 2130
pF1KB4 GPPGLPGTPGPPGPPGPKVSVDEPGP-GLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVP
:: ::::::: :: : . :: : : ::::::.: :: :. : :::::::
CCDS87 GPRGLPGTPGTDGPKGAS------GPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRG--
650 660 670 680 690
2140 2150 2160 2170 2180 2190
pF1KB4 GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLA
: :: :: .: :: : :: : :: :::::.:..:. : : ::
CCDS87 ----DVGEKGP---EGAPGKDGGRG---------LTGPIGPPGPAGANGEKGEVGPPG--
700 710 720 730 740
2200 2210 2220 2230 2240 2250
pF1KB4 GPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGET
::: : : :: ::::::: :..:: :: : :: : .: .: .:. : :: : .
CCDS87 -PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPS
750 760 770 780 790 800
2260 2270 2280 2290 2300 2310
pF1KB4 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKG
: :: : :..: : ::. : ::. :.:: .: : :: .: :: : :: .:. :
CCDS87 GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPP--GPPGPSGKDG
810 820 830 840 850
2320 2330 2340 2350 2360 2370
pF1KB4 APGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPG-
: : :: : :: :. :: :: : :: : :::: : .: .: :::.:. :. :
CCDS87 -PKGARGD-SGPPGRAGEPGLQGPAGPPGEKG---EPGDDGPSGAEGPPGPQGLAGQRGI
860 870 880 890 900 910
2380 2390 2400 2410 2420 2430
pF1KB4 VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGR
::.::. : : :: ::: : :: : :: .: :: : :: : : :: :::
CCDS87 VGLPGQRGERGFPG------LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGR
920 930 940 950 960
2440 2450 2460 2470 2480
pF1KB4 EGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV----GLPGPRGERGEPGIRGEDGRPGQ
:: :: :::: :..: : : : : ::. : ::: : :. : ::: : :
CCDS87 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP
970 980 990 1000 1010 1020
2490 2500 2510 2520 2530 2540
pF1KB4 EGP------RGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERG
:: ::. :: : ::..:: :. : :::: .: .. . : ::: : .::.: :
CCDS87 MGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG-LQGLPGPPGPSGDQGASG
1030 1040 1050 1060 1070 1080
2550 2560 2570 2580 2590 2600
pF1KB4 PRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG
: : .: .:: : : : :..: :: : : : : :: : :: : :: :: ::
CCDS87 PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG
1090 1100 1110 1120 1130 1140
2610 2620 2630 2640 2650 2660
pF1KB4 KDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMG
::: . . . .::: :: :. ..:.. :: :: : .:.
CCDS87 ----PGI--DMSAFAGLGPRE-------KGPDPLQYMRADQA-AG-----GLRQHDAEVD
1150 1160 1170 1180
2670 2680 2690 2700 2710 2720
pF1KB4 EPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAG
. .: :.. .:.:.:
CCDS87 ---ATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKV
1190 1200 1210 1220 1230 1240
>>CCDS9511.1 COL4A1 gene_id:1282|Hs108|chr13 (1669 aa)
initn: 1193 init1: 1193 opt: 3261 Z-score: 1214.8 bits: 238.6 E(32554): 2.4e-61
Smith-Waterman score: 4138; 44.9% identity (57.7% similar) in 1562 aa overlap (1247-2769:39-1432)
1220 1230 1240 1250 1260 1270
pF1KB4 DDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGL
: . :::::: : ::.: .: .
CCDS95 LLLLPAALLLHEEHSRAAAKGGCAGSGCGKCDCHGVKGQKGERGLPGLQGVIG------F
10 20 30 40 50 60
1280 1290 1300 1310 1320 1330
pF1KB4 PGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGD
:: : :::::::. :: :.::. : : :: .: ::.:: ::. :. : ::: :
CCDS95 PGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGI
70 80 90 100 110 120
1340 1350 1360 1370 1380 1390
pF1KB4 PGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGT
:: : .: .: : .: ::::: :.::: : :: .: ::: . .::
CCDS95 PGCNGTKGERG-PLGP--------PGLPGFAGNPGPPGLPGMKG---DPG-EILGHVPGM
130 140 150 160
1400 1410 1420 1430 1440 1450
pF1KB4 AMKGDKGDRGERGPPGP-GEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAP
.::..: : : ::: : :. : : ::. : ::: :: ::::.::. : :
CCDS95 LLKGERGFPGIPGTPGPPGLPGLQ-GPVGPPGFTGPPGPPGPPGPPGEKGQMGLS-----
170 180 190 200 210 220
1460 1470 1480 1490 1500 1510
pF1KB4 GLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVA--G
. : :. :.:: ::::. : ... : .. ::::..: : : .:.:::. :
CCDS95 -FQGPKGDKGDQGVSGPPGVPG-QAQVQEKGDFATKGEKGQKGEP---GFQGMPGVGEKG
230 240 250 260 270
1520 1530 1540 1550 1560
pF1KB4 RPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVG-PAVAGPKGEKGDVGPAGPRG---ATG
.:: ::.: :: : .:::: :: ::.:. : . ::.::::..:: :: : .::
CCDS95 EPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTG
280 290 300 310 320 330
1570 1580 1590 1600 1610 1620
pF1KB4 VQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGP-PGEKGDPGRPGPPGPVG
::.: : :: :::.:.:: .: :: :. :::: : ::. : :: ::
CCDS95 PLGEKGERG--YPGTPGPRGEPGPKGFPGLPGQPGPPGL--PVPGQAGAPGFPG------
340 350 360 370 380
1630 1640 1650 1660 1670 1680
pF1KB4 PRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNG-SP
: :::::.: :: .::: .:. :: : :: :: :.:: ::
CCDS95 ------ERGEKGDRGFPGT-SLPGPSGRDGLPGPPGSPGP------PGQPGYT--NGIVE
390 400 410 420 430
1690 1700 1710 1720 1730
pF1KB4 GSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEP-------GDRGQEGPRGPKGD---PG
. :: ::.: :: :: :: . . : . .::: : :: ::.:: :. ::
CCDS95 CQPGPPGDQGPPGIPGQPGFIGEIGEKG-QKGESCLICDIDGYRGPPGPQGPPGEIGFPG
440 450 460 470 480 490
1740 1750 1760 1770 1780 1790
pF1KB4 LPGAPGERGI---EGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSG
::: :.::. .: : ::::: ::. : : ::. : .: : : : : : :
CCDS95 QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLR--LKGDKGDPGFPG
500 510 520 530 540 550
1800 1810 1820 1830 1840 1850
pF1KB4 PNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDG
: :.::.::::: ::: : .: :: : : : :: : :: : .: :: :: :
CCDS95 QPGMPGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY-G
560 570 580 590 600
1860 1870 1880 1890 1900 1910
pF1KB4 RKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPG--LPGPVGPPG-QGFPGVPGGTGP
: ::.: .: : :: :.::. ::.: :: .: : :::: .:.:: :: ::
CCDS95 PAGPIGDKGQAGFPG--GP----GSPGLPGPKGEPGKIVPLP-GPPGAEGLPGSPGFPGP
610 620 630 640 650 660
1920 1930 1940 1950 1960 1970
pF1KB4 KGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFL
.:::: :. :. :::::.: :.:: .
CCDS95 QGDRGFPGTPGRPGLPGEKGAVGQPG---------------------------------I
670 680
1980 1990 2000 2010 2020 2030
pF1KB4 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPS-
: :: : .: .: :: :: : ::. :..: :.:: :: ..: :: .
CCDS95 GFP----GPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQG-------QKGEPGVGL
690 700 710 720 730
2040 2050 2060 2070 2080
pF1KB4 -GLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGP
:: : :: ::::: ::. :..: : :::.: : : .: .:. :::::::. : ::
CCDS95 PGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGV
740 750 760 770 780 790
2090 2100 2110 2120 2130 2140
pF1KB4 PG--PKVSVDEPG-PGLSGEQGPPGLKGAKGEPGSNG-DQ-GPKGDRG---VPGIKGDRG
:: : . :: : : .::::.:: :: :: : :. :::::.: .::: :. :
CCDS95 PGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSG
800 810 820 830 840 850
2150 2160 2170 2180 2190 2200
pF1KB4 EPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQG
:: ::.: ::.:: : : : : : : :::::. : :: : :. : .::.:
CCDS95 LPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRG
860 870 880 890 900 910
2210 2220 2230 2240 2250 2260
pF1KB4 PSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGR
::::. :..: ::. : : . . : . : :: : : .:: :. : ::
CCDS95 DPGLKGDKGDVGLPGK--PGSMDKVDMGSMKGQK---GDQGEKGQIGPIGEKGSRGDPGT
920 930 940 950 960 970
2270 2280 2290 2300 2310
pF1KB4 DGASGKDGDRGSPGVPG---SPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGL
:. ::::. :.:: :: .::. : : : ::: :. : .::::. ::::.::
CCDS95 PGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGG--MGLPGTPGEKGVPGI-
980 990 1000 1010 1020 1030
2320 2330 2340 2350 2360 2370
pF1KB4 AGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGS
:: .:. :::: .: ::: :.:: :: : :: .: ::: :.. :
CCDS95 -------PGPQGSPGLPGDKGAKGEKGQAGPPG-------IGIPGLRGEKGDQGIA--GF
1040 1050 1060 1070
2380 2390 2400 2410 2420 2430
pF1KB4 PGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGP
:: :: : ::..:.::.::.::. : ::..: : : :: .:..:: :: .::::
CCDS95 PGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGL---PGLDGIPGV
1080 1090 1100 1110 1120 1130
2440 2450 2460 2470 2480 2490
pF1KB4 LGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPP
: : ::. :: : .: ::. :. :. :: ::.::::. :: ::. : :
CCDS95 KGEAGLPGTPGPTGPAGQKGEPGSDGI--PGSAGEKGEPGL------PG----RGFPGFP
1140 1150 1160 1170
2500 2510 2520 2530 2540 2550
pF1KB4 GSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGD
:..:..: ::.:: :: :. : :: .: .: :: ::.: : : :
CCDS95 GAKGDKGSKGEVGFPGLAGSPG-------IPGSKGEQGFMGPPGPQGQPGLPGSPGH---
1180 1190 1200 1210 1220
2560 2570 2580 2590 2600 2610
pF1KB4 PGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGF
. .: ::. : .:. ::::: : .:: : :: :. :: :.:: :.::. : ::: ::
CCDS95 -ATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGF
1230 1240 1250 1260 1270 1280
2620 2630 2640 2650 2660 2670
pF1KB4 MGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGL
.: :. : :. :. : : : : :: : ::: : ::..:. :::: .: :: :
CCDS95 QGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGP
1290 1300 1310 1320 1330 1340
2680 2690 2700 2710 2720 2730
pF1KB4 IGPKGD-RGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEG
:: .: : :::.: : :: .: :: : : .: : :::: :: .:
CCDS95 PGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGF------DG
1350 1360 1370 1380 1390 1400
2740 2750 2760 2770 2780 2790
pF1KB4 LQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQE
::::: :: : .: : :: :: : :
CCDS95 APGQKGEMGPAGP--TGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTIDDPQC
1410 1420 1430 1440 1450 1460
2800 2810 2820 2830 2840 2850
pF1KB4 MSQHCACQGQFIASGSRPLPSYAADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSE
CCDS95 PSGTKILYHGYSLLYVQGNERAHGQDLGTAGSCLRKFSTMPFLFCNINNVCNFASRNDYS
1470 1480 1490 1500 1510 1520
>>CCDS6982.1 COL5A1 gene_id:1289|Hs108|chr9 (1838 aa)
initn: 2828 init1: 1049 opt: 3197 Z-score: 1191.0 bits: 234.3 E(32554): 5.1e-60
Smith-Waterman score: 3526; 40.9% identity (52.9% similar) in 1573 aa overlap (1208-2745:220-1585)
1180 1190 1200 1210 1220 1230
pF1KB4 REAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGLATALCQAS
: : .:. : . : . :...
CCDS69 FLDRSDHPMIDINGIIVFGTRILDEEVFEGDIQQLLFVSDHRAAYDYCEH--YSPDCDTA
190 200 210 220 230 240
1240 1250 1260 1270 1280 1290
pF1KB4 FTTQPRPE-PCP-VYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAK
:. . : : : .:. :: :: . :: :. : :. : : ::
CCDS69 VPDTPQSQDPNPDEYYTEGD-GE-GET-YYYEYPYYEDPEDLGKE--PTPSKKPVEA-AK
250 260 270 280 290 300
1300 1310 1320 1330 1340 1350
pF1KB4 GERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQV
: . : : : : . : . . :. :: . : :. ..
CCDS69 ETTEVP-EELTPTPTEAAPMPETSEGAGKEEDVGI----GDY-DYVPSEDYYTPSPYDDL
310 320 330 340 350
1360 1370 1380 1390 1400 1410
pF1KB4 IGGEGPGLPGRKGDPGPSG--PPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPP--
::: : . ::: .. : . .. .: ::: . ..:. .. :.
CCDS69 TYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDEN
360 370 380 390 400 410
1420 1430 1440 1450 1460
pF1KB4 --GPG-EGGIAPGEPGLPGLPGSPGP--QGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGE
: . .:.: : ::.:.. .: :: :.::.::. ::. . : ::
CCDS69 YYDPYYDPTSSPSEIG-PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIE-GPPGP
420 430 440 450 460 470
1470 1480 1490 1500 1510 1520
pF1KB4 QGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGP
.:: : :: : : : : :..:. ::::::: ::. ::: : ::::
CCDS69 EGPAGLPG---PPGTMG---PTGQVGDPGERGPPG------RPGL---PGADGLPGPPGT
480 490 500 510
1530 1540 1550 1560 1570
pF1KB4 TGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDV---------GPAGPRGATGVQGERGPP
. : :: . :: :.. ... . ::::: : :: : :::
CCDS69 MLMLPFRFGGG--GDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPP
520 530 540 550 560 570
1580 1590 1600 1610 1620 1630
pF1KB4 GLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVG
: . : ::.::: :: :: : .:::: : ::: : : : :: :..:
CCDS69 G-----SGGLKGEPGDVGP------QGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTG
580 590 600 610 620
1640 1650 1660 1670 1680 1690
pF1KB4 EKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRG
:::.: : ::::. :.:: : : :: :. :..:: :: : : :: ::.: :
CCDS69 PKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLG
630 640 650 660 670 680
1700 1710 1720 1730 1740 1750
pF1KB4 EPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQ
::::::: ::. : :: ::.: : : :: ::..: : .: ::::
CCDS69 PKGPPGPPG-----PPGVT-----GMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQ
690 700 710 720 730
1760 1770 1780 1790 1800 1810
pF1KB4 GDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQ
: . :: :::: : ::: : : :: :: ::..: :: .: :
CCDS69 G---AIGPPGEKGPLGKPGLPGMPGADGPPG---------------HPGKEGPPGEKGGQ
740 750 760 770
1820 1830 1840 1850 1860 1870
pF1KB4 GLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGER
: :::.:: : :: : : :. : .: :. :::: : ::: : .: .:. :: : :
CCDS69 GPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPR
780 790 800 810 820 830
1880 1890 1900 1910 1920 1930
pF1KB4 GAPGILGPQG---PPGLPGPVGPPGQ----GFPGVPGGTGPKGDRGETGSKGEQGLPGER
: : ::.: : : :::.::::. : ::.:: : .: .: : : : ::.
CCDS69 GEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEK
840 850 860 870 880 890
1940 1950 1960 1970 1980 1990
pF1KB4 GLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPP
: :: :: . ::.:. : ::
CCDS69 GGRGTPG---------------------------------------KPGPRGQRGPTGPR
900 910
2000 2010 2020 2030 2040 2050
pF1KB4 GKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGG
:..:: :. :. : ::. : :: :::: :::: ::.: .: :: : :: ::.
CCDS69 GERGPRGITGKPGPKGNSGGDGPAGPPG----ERGPNGPQGPTGFPGPKGPPGPPGKD--
920 930 940 950 960 970
2060 2070 2080 2090 2100
pF1KB4 VGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGP-GLSGEQGP
: :.::.: :: : ::. :::: ::. :: :: : : :: : :. ::
CCDS69 -GLPGHPGQR------GETGFQGKTGPPGPPGVVGPQGPTG------ETGPMGERGHPGP
980 990 1000 1010
2110 2120 2130 2140 2150 2160
pF1KB4 PGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGL
:: : .: :: : .: ::: : :. : : :: :: .::.::. :: : ::
CCDS69 PGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRG------FPGDRGLPGPVGALGL
1020 1030 1040 1050 1060 1070
2170 2180 2190 2200 2210 2220
pF1KB4 QGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLP
.: .::::: ::: :.:: :::: :: :. :.:: :::: .: :: :
CCDS69 KGNEGPPGP------PGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGP--AGEKGAPGEK
1080 1090 1100 1110 1120
2230 2240 2250 2260 2270 2280
pF1KB4 GPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPK
:: ::.: : :: :::: .: .: :: : : :. :..:: : : : :::.::.
CCDS69 GPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQ
1130 1140 1150 1160 1170 1180
2290 2300 2310 2320 2330 2340
pF1KB4 G---EPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGR
: .:::.:: :. :: .:..: : :. : .: ::.::: : : :
CCDS69 GPIGQPGPSGADGE-----PGPRGQQG--------LFGQKGDEGPRGFPGPPGPVGLQGL
1190 1200 1210 1220 1230
2350 2360 2370 2380 2390 2400
pF1KB4 AGEPGDPGEDG---QKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVV
: ::. :: : : : ::: : .: :. :.::. :: :::: :. : : : :: .
CCDS69 PGPPGEKGETGDVGQMGPPGPPGPRG-PS-GAPGADGPQGPPGGIGNPGAVGEKGEPGEA
1240 1250 1260 1270 1280 1290
2410 2420 2430 2440 2450 2460
pF1KB4 GFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDP
: :: : :: : :::.:::: : : : :: :: ::::. :: :. : : :::
CCDS69 GEPGL--P-GEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDP
1300 1310 1320 1330 1340
2470 2480 2490 2500 2510 2520
pF1KB4 GV-GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDS
: : ::: :. : :: .:.::.::: : : :: :: : :..:
CCDS69 GPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRG--------------
1350 1360 1370 1380 1390
2530 2540 2550 2560 2570 2580
pF1KB4 AVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGL
:::: : .: .::.: .: : .:: : .: : .:. :.:: ::::.
CCDS69 -----PPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGP------DGLRGI
1400 1410 1420 1430 1440
2590 2600 2610 2620 2630 2640
pF1KB4 LGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGD
:: :. : : :: : :: : ::. : ::: ::.: ::. :. : : ::.:.
CCDS69 PGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGD---SGPKGEKGHPGLIGLIGPPGEQGE
1450 1460 1470 1480 1490
2650 2660 2670 2680 2690 2700
pF1KB4 KGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGE
::. : :: : .: :::.: . : :: : ::: : :. : ::::: .: .:
CCDS69 KGDRGLPGPQGSSGPKGEQG---ITGPSG-P-----IGPPGPPGLPGPPGPKGAKGSSGP
1500 1510 1520 1530 1540 1550
2710 2720 2730 2740 2750 2760
pF1KB4 RGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAP
: : .: ::: ::::::: : : .:... .:
CCDS69 TGPKGEAGHPGP------PGPPGPPGEVIQ--PLPIQASRTRRNIDASQLLDDGNGENYV
1560 1570 1580 1590 1600
2770 2780 2790 2800 2810 2820
pF1KB4 GERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYAAD
CCDS69 DYADGMEEIFGSLNSLKLEIEQMKRPLGTQQNPARTCKDLQLCHPDFPDGEYWVDPNQGC
1610 1620 1630 1640 1650 1660
>>CCDS75932.1 COL5A1 gene_id:1289|Hs108|chr9 (1838 aa)
initn: 2828 init1: 1049 opt: 3197 Z-score: 1191.0 bits: 234.3 E(32554): 5.1e-60
Smith-Waterman score: 3526; 40.9% identity (52.9% similar) in 1573 aa overlap (1208-2745:220-1585)
1180 1190 1200 1210 1220 1230
pF1KB4 REAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQAVSGLATALCQAS
: : .:. : . : . :...
CCDS75 FLDRSDHPMIDINGIIVFGTRILDEEVFEGDIQQLLFVSDHRAAYDYCEH--YSPDCDTA
190 200 210 220 230 240
1240 1250 1260 1270 1280 1290
pF1KB4 FTTQPRPE-PCP-VYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAK
:. . : : : .:. :: :: . :: :. : :. : : ::
CCDS75 VPDTPQSQDPNPDEYYTEGD-GE-GET-YYYEYPYYEDPEDLGKE--PTPSKKPVEA-AK
250 260 270 280 290 300
1300 1310 1320 1330 1340 1350
pF1KB4 GERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQV
: . : : : : . : . . :. :: . : :. ..
CCDS75 ETTEVP-EELTPTPTEAAPMPETSEGAGKEEDVGI----GDY-DYVPSEDYYTPSPYDDL
310 320 330 340 350
1360 1370 1380 1390 1400 1410
pF1KB4 IGGEGPGLPGRKGDPGPSG--PPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPP--
::: : . ::: .. : . .. .: ::: . ..:. .. :.
CCDS75 TYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDEN
360 370 380 390 400 410
1420 1430 1440 1450 1460
pF1KB4 --GPG-EGGIAPGEPGLPGLPGSPGP--QGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGE
: . .:.: : ::.:.. .: :: :.::.::. ::. . : ::
CCDS75 YYDPYYDPTSSPSEIG-PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIE-GPPGP
420 430 440 450 460 470
1470 1480 1490 1500 1510 1520
pF1KB4 QGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGP
.:: : :: : : : : :..:. ::::::: ::. ::: : ::::
CCDS75 EGPAGLPG---PPGTMG---PTGQVGDPGERGPPG------RPGL---PGADGLPGPPGT
480 490 500 510
1530 1540 1550 1560 1570
pF1KB4 TGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDV---------GPAGPRGATGVQGERGPP
. : :: . :: :.. ... . ::::: : :: : :::
CCDS75 MLMLPFRFGGG--GDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPP
520 530 540 550 560 570
1580 1590 1600 1610 1620 1630
pF1KB4 GLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVG
: . : ::.::: :: :: : .:::: : ::: : : : :: :..:
CCDS75 G-----SGGLKGEPGDVGP------QGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTG
580 590 600 610 620
1640 1650 1660 1670 1680 1690
pF1KB4 EKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRG
:::.: : ::::. :.:: : : :: :. :..:: :: : : :: ::.: :
CCDS75 PKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLG
630 640 650 660 670 680
1700 1710 1720 1730 1740 1750
pF1KB4 EPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQ
::::::: ::. : :: ::.: : : :: ::..: : .: ::::
CCDS75 PKGPPGPPG-----PPGVT-----GMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQ
690 700 710 720 730
1760 1770 1780 1790 1800 1810
pF1KB4 GDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQ
: . :: :::: : ::: : : :: :: ::..: :: .: :
CCDS75 G---AIGPPGEKGPLGKPGLPGMPGADGPPG---------------HPGKEGPPGEKGGQ
740 750 760 770
1820 1830 1840 1850 1860 1870
pF1KB4 GLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGER
: :::.:: : :: : : :. : .: :. :::: : ::: : .: .:. :: : :
CCDS75 GPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPR
780 790 800 810 820 830
1880 1890 1900 1910 1920 1930
pF1KB4 GAPGILGPQG---PPGLPGPVGPPGQ----GFPGVPGGTGPKGDRGETGSKGEQGLPGER
: : ::.: : : :::.::::. : ::.:: : .: .: : : : ::.
CCDS75 GEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEK
840 850 860 870 880 890
1940 1950 1960 1970 1980 1990
pF1KB4 GLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPP
: :: :: . ::.:. : ::
CCDS75 GGRGTPG---------------------------------------KPGPRGQRGPTGPR
900 910
2000 2010 2020 2030 2040 2050
pF1KB4 GKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGG
:..:: :. :. : ::. : :: :::: :::: ::.: .: :: : :: ::.
CCDS75 GERGPRGITGKPGPKGNSGGDGPAGPPG----ERGPNGPQGPTGFPGPKGPPGPPGKD--
920 930 940 950 960 970
2060 2070 2080 2090 2100
pF1KB4 VGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGP-GLSGEQGP
: :.::.: :: : ::. :::: ::. :: :: : : :: : :. ::
CCDS75 -GLPGHPGQR------GETGFQGKTGPPGPPGVVGPQGPTG------ETGPMGERGHPGP
980 990 1000 1010
2110 2120 2130 2140 2150 2160
pF1KB4 PGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGL
:: : .: :: : .: ::: : :. : : :: :: .::.::. :: : ::
CCDS75 PGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRG------FPGDRGLPGPVGALGL
1020 1030 1040 1050 1060 1070
2170 2180 2190 2200 2210 2220
pF1KB4 QGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLP
.: .::::: ::: :.:: :::: :: :. :.:: :::: .: :: :
CCDS75 KGNEGPPGP------PGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGP--AGEKGAPGEK
1080 1090 1100 1110 1120
2230 2240 2250 2260 2270 2280
pF1KB4 GPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPK
:: ::.: : :: :::: .: .: :: : : :. :..:: : : : :::.::.
CCDS75 GPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQ
1130 1140 1150 1160 1170 1180
2290 2300 2310 2320 2330 2340
pF1KB4 G---EPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGR
: .:::.:: :. :: .:..: : :. : .: ::.::: : : :
CCDS75 GPIGQPGPSGADGE-----PGPRGQQG--------LFGQKGDEGPRGFPGPPGPVGLQGL
1190 1200 1210 1220 1230
2350 2360 2370 2380 2390 2400
pF1KB4 AGEPGDPGEDG---QKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVV
: ::. :: : : : ::: : .: :. :.::. :: :::: :. : : : :: .
CCDS75 PGPPGEKGETGDVGQMGPPGPPGPRG-PS-GAPGADGPQGPPGGIGNPGAVGEKGEPGEA
1240 1250 1260 1270 1280 1290
2410 2420 2430 2440 2450 2460
pF1KB4 GFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDP
: :: : :: : :::.:::: : : : :: :: ::::. :: :. : : :::
CCDS75 GEPGL--P-GEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDP
1300 1310 1320 1330 1340
2470 2480 2490 2500 2510 2520
pF1KB4 GV-GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDS
: : ::: :. : :: .:.::.::: : : :: :: : :..:
CCDS75 GPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRG--------------
1350 1360 1370 1380 1390
2530 2540 2550 2560 2570 2580
pF1KB4 AVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGL
:::: : .: .::.: .: : .:: : .: : .:. :.:: ::::.
CCDS75 -----PPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGP------DGLRGI
1400 1410 1420 1430 1440
2590 2600 2610 2620 2630 2640
pF1KB4 LGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGD
:: :. : : :: : :: : ::. : ::: ::.: ::. :. : : ::.:.
CCDS75 PGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGD---SGPKGEKGHPGLIGLIGPPGEQGE
1450 1460 1470 1480 1490
2650 2660 2670 2680 2690 2700
pF1KB4 KGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGE
::. : :: : .: :::.: . : :: : ::: : :. : ::::: .: .:
CCDS75 KGDRGLPGPQGSSGPKGEQG---ITGPSG-P-----IGPPGPPGLPGPPGPKGAKGSSGP
1500 1510 1520 1530 1540 1550
2710 2720 2730 2740 2750 2760
pF1KB4 RGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAP
: : .: ::: ::::::: : : .:... .:
CCDS75 TGPKGEAGHPGP------PGPPGPPGEVIQ--PLPIQASRTRRNIDASQLLDDGNGENYV
1560 1570 1580 1590 1600
2770 2780 2790 2800 2810 2820
pF1KB4 GERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYAAD
CCDS75 DYADGMEEIFGSLNSLKLEIEQMKRPLGTQQNPARTCKDLQLCHPDFPDGEYWVDPNQGC
1610 1620 1630 1640 1650 1660
>>CCDS41907.1 COL4A2 gene_id:1284|Hs108|chr13 (1712 aa)
initn: 753 init1: 753 opt: 3191 Z-score: 1189.1 bits: 233.9 E(32554): 6.5e-60
Smith-Waterman score: 3740; 43.2% identity (55.3% similar) in 1585 aa overlap (1247-2763:51-1483)
1220 1230 1240 1250 1260 1270
pF1KB4 DDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGD---
: : :: .:.:: .: .: ::::
CCDS41 TVTVGFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGF
30 40 50 60 70 80
1280 1290 1300 1310 1320
pF1KB4 PGLPGRTG------APGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGS
::: :: : ::: :: :.. :.: ::::::: :: ::..: : :: : .:.
CCDS41 PGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGT
90 100 110 120 130 140
1330 1340 1350 1360
pF1KB4 PGLPGPRGDPGERG------PRGPKG------------------EPGAPGQVIGGEGP-G
: ::.: :: .: :.:::: ::: :: ..: .:: :
CCDS41 QGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPG-LVGFQGPPG
150 160 170 180 190
1370 1380 1390 1400 1410 1420
pF1KB4 LPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGE
::. :. :: : :: :: : :::.: : : .. : ::..:. : :::. :: :..
CCDS41 RPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPN--GI-PSD
200 210 220 230 240 250
1430 1440 1450 1460 1470
pF1KB4 PGLP-----GLPGSP----GPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPP
: :. : : .: : :: .: . .:.: :.:: : :: .: .: :
CCDS41 TLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSP
260 270 280 290 300 310
1480 1490 1500 1510 1520 1530
pF1KB4 GAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPG-AKGPEGPPGPTGRQGE
: : .: :. :: : : ::: : ::: :::. . .:. ::: .: :: : :::
CCDS41 GQKGSRGLDGYQGPDGPRGPKGEAGDPGPP---GLPAYSPHPSLAKGARGDPGFPGAQGE
320 330 340 350 360 370
1540 1550 1560 1570 1580
pF1KB4 KGEPGRPGDPAVVGP---AVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKG
: :.::::.. :: ... ..: : ::.: :. : :.: : ::: :
CCDS41 PGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFI---GDPGIPALY-GGPPGPDG
380 390 400 410 420
1590 1600 1610 1620 1630 1640
pF1KB4 DPGDRGPIGLTGRAGPPG----DSGPPGEKGDPGRPGPPGPVGPRGRDGEVGE----KGD
: :: :: : :: : .: :. : :: :: :: ::.: :..:: .::
CCDS41 KRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGD
430 440 450 460 470 480
1650 1660 1670 1680 1690 1700
pF1KB4 EGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGP
:. : ::::: : :. : :: .:::.::::. : : :: .: :. : :::
CCDS41 EAIKGLPGLPGPKGFAGINGEPG------RKGDRGDPGQHGLPGFPGLKGVPGNIGAPGP
490 500 510 520 530 540
1710 1720 1730 1740 1750 1760
pF1KB4 PGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPG
: : .: :.::: : : : : :.::. :..:: : ::: :: :
CCDS41 KGAKG-------DSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-G
550 560 570 580 590
1770 1780 1790 1800 1810 1820
pF1KB4 VRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPG
..:: :. : : :: : : : :: . : : :. : :: :::: : : ::
CCDS41 IKGPPGDPGYPGIPGTKGTPGEMGPPGLGLP----GLKGQRGFPGDAGLPGPPGFLGPPG
600 610 620 630 640 650
1830 1840 1850 1860 1870 1880
pF1KB4 PSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPG
:.: :: : : ...: : .:: : : :: : : : : :: :: ::
CCDS41 PAGTPGQIDCD-TDVKRAVGGDRQEAIQPGCIG--GPKGLPGLPGPPGPTGAKGLRGIPG
660 670 680 690 700
1890 1900 1910 1920 1930
pF1KB4 ILGPQGPPG---LPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGS
. : .: :: ::: .: .:::: :: ::.:..: .: : .: :: :: : :
CCDS41 FAGADGGPGPRGLPGDAGR--EGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDG-
710 720 730 740 750 760
1940 1950 1960 1970 1980 1990
pF1KB4 VPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGF
: .: :. . .: :. : ::.::.: : :: .: .
CCDS41 -PPGER-----GLPGEVL-----------GA-QP------GPRGDAGVPGQPGLKG---L
770 780 790
2000 2010 2020 2030 2040 2050
pF1KB4 PGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPG
::.:: : ::. : : ::: :. : ::::: : : ::. :.:: : : : ::
CCDS41 PGDRGPPGFRGSQGMPGMPGLK-GQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPG
800 810 820 830 840 850
2060 2070 2080 2090 2100 2110
pF1KB4 ERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGE
:..: :.::. :: :.::: : : .: :. :..:::: :: : ::
CCDS41 IPGREGLPGDRGD------PGDTGAPGPVGMKG--LSGDRGDAGFTGEQGHPGSPGFKGI
860 870 880 890 900
2120 2130 2140 2150 2160 2170
pF1KB4 PGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGP
: : : ::::: ::. : .: :: .:. ::.:: .: :: : :::.: : ::
CCDS41 DGMPGTPGLKGDRGSPGMDGFQGMPGLKGR---PGFPGSKGEAGFFGIPGLKGLAGEPGF
910 920 930 940 950 960
2180 2190 2200 2210 2220 2230
pF1KB4 VGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGL
:..::::::: : . : : . .::: :. :: : .: : : :.:: :: ::.
CCDS41 KGSRGDPGPPGPPPVILP----GMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGI
970 980 990 1000 1010 1020
2240 2250 2260 2270 2280 2290
pF1KB4 VGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGA
:::::. ::. .: :: : ::.:: ::.:: .:: :: ::
CCDS41 ------PGLPGR---------PGH--IKGVKGDIGVPGIPGLPGFPGVAGP---PGITGF
1030 1040 1050 1060
2300 2310 2320 2330 2340 2350
pF1KB4 PGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRG-------LPGPRGEKGEAGRAGEP
:: . :..:.::::: :: : :: :: :: : ::: : ::: : .: :
CCDS41 PG-----FIGSRGDKGAPGR-AG-LYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIP
1070 1080 1090 1100 1110
2360 2370 2380 2390 2400 2410
pF1KB4 GDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTG
: : :.::. : :: :: . : : ::::.::. :.::: : :: : :. :
CCDS41 GLKGFFGEKGTEGDIGF---PG--ITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIG
1120 1130 1140 1150 1160 1170
2420 2430 2440 2450 2460 2470
pF1KB4 PRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGP
: :. : : :: : :: .:: : : :: : : ::.. .:::: .:::
CCDS41 LPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDI----HGDPG--FPGP
1180 1190 1200 1210 1220
2480 2490 2500 2510 2520 2530
pF1KB4 RGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPG
::::.:: . : :: :. : :..: ::.: :: ::.: : : : .
CCDS41 PGERGDPG--EANTLP---GPVGVPGQKGDQGAPGERGPPGSPGLQGFPG----ITPPSN
1230 1240 1250 1260 1270
2540 2550 2560 2570 2580 2590
pF1KB4 PRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPG
:: :: : : :: : .:: :: :: . ::.::..: :: .: : ::
CCDS41 ISGAPGDKGAPGIFGLKGYRGP------PGPPGSAALPGSKGDTGNPG-----AP-GTPG
1280 1290 1300 1310 1320
2600 2610 2620 2630 2640 2650
pF1KB4 AAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPG
. : :: : :. :: :. :::: ::: :.: : : : ::.: :: :
CCDS41 TKGWAGDSGPQGRPGVFGLPGEKG------PRG---EQGFMGNTGPTGAVGDRGPKGPKG
1330 1340 1350 1360 1370
2660 2670 2680 2690 2700
pF1KB4 RPGLAGHKGEMGEPGVPG--QSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGI
::. : : .: ::. : :. : . : .::.: :: : :: : :: :: ::.
CCDS41 DPGFPGAPGTVGAPGIAGIPQKIAV-QPGTVGPQGRRGPPGAPGEMGPQGPPGE---PGF
1380 1390 1400 1410 1420 1430
2710 2720 2730 2740 2750 2760
pF1KB4 GGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQ
: :: .: .: .: . :: : .:: : :: :..: ::. :.::.:: ::
CCDS41 RGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRP--GSPGLPGMPGRSVSI
1440 1450 1460 1470 1480
2770 2780 2790 2800 2810 2820
pF1KB4 GRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYAADTAGSQL
CCDS41 GYLLVKHSQTDQEPMCPVGMNKLWSGYSLLYFEGQEKAHNQDLGLAGSCLARFSTMPFLY
1490 1500 1510 1520 1530 1540
>>CCDS14542.1 COL4A6 gene_id:1288|Hs108|chrX (1690 aa)
initn: 2360 init1: 1198 opt: 3161 Z-score: 1178.2 bits: 231.8 E(32554): 2.6e-59
Smith-Waterman score: 3665; 42.5% identity (54.5% similar) in 1586 aa overlap (1247-2769:39-1466)
1220 1230 1240 1250 1260 1270
pF1KB4 DDGPSLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGL
: . :: .:.:: .:..: .:: : .
CCDS14 LVTLCLTEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQG---F
10 20 30 40 50 60
1280 1290 1300 1310 1320 1330
pF1KB4 PGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGD
: :: : :::::::: : : .: :. : :.::. : :.::
CCDS14 TGSTGLSG---------LKGERGFPGLLG-PYGP--KGDKGPMGVPGFLGINGIPG---H
70 80 90 100 110
1340 1350 1360 1370 1380 1390
pF1KB4 PGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGT
::. ::::: ::: : .: : : ::: : :: :::::::
CCDS14 PGQPGPRGP---------------PGLDGCNGTQGAVGFPGPD---GYPGLLGPPGLPG-
120 130 140 150
1400 1410 1420 1430 1440 1450
pF1KB4 AMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPG
.::.::: :: .: :.:::::: : :::: .: : ::
CCDS14 -QKGSKGD--PVLAPGSFKG--MKGDPGLPGLDGITGPQG--AP------------GFPG
160 170 180 190
1460 1470 1480 1490 1500 1510
pF1KB4 LPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAG---SRGLPGVAG
: : :: ::: :::: .:: :. :. : :: : ::. : ::::: : : :
CCDS14 AVGPAGPPGLQGPPGPPGPLGPDGNMGL-GFQGEKGVKGDVGLPGPAGPPPSTGELEFMG
200 210 220 230 240 250
1520 1530 1540 1550 1560 1570
pF1KB4 RP-GAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQG
: : :: .: ::: : : .: :: :: ...: : ::::: : :::: : .:
CCDS14 FPKGKKGSKGEPGPKGFPGISGPPGFPGL-GTTGEK--GEKGEKGIPGLPGPRGPMGSEG
260 270 280 290 300
1580 1590 1600 1610 1620
pF1KB4 ERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPP------GE--KGDPGRPGPP
.:::: : : : :: : :. :. : : :: : .:.:: :: :
CCDS14 VQGPPGQ--QGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVP
310 320 330 340 350 360
1630 1640 1650 1660 1670 1680
pF1KB4 GPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRN
: : .: .: : .: : :: :.: : : : .: ::. :::::.::.
CCDS14 GLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGL------KGDQGNPGRT-TI
370 380 390 400 410
1690 1700 1710 1720 1730
pF1KB4 GSPGSSGPKGDRGEPGPPGPPGRLVDTGP-GAREKGEPGDRGQEGPRGP------KGDPG
:. : : : : :::::::. .: .:.: :: ::..::.: ::: :
CCDS14 GAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSG
420 430 440 450 460 470
1740 1750 1760 1770 1780 1790
pF1KB4 L----PGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPS
. :.:. : : ::::: : :. : : .:::: : .: .: :: .::
CCDS14 FCACDGGVPNT-GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAG---APGLVGPL
480 490 500 510 520 530
1800 1810 1820 1830 1840 1850
pF1KB4 GPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED
::.: :: :.: . . :. :..: : .: :. :.::.:: ::: : : ::: :.
CCDS14 GPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-
540 550 560 570 580 590
1860 1870 1880 1890 1900 1910
pF1KB4 GRKGEKGDSGASGREGRDGPKGE--RGAPGILGPQGPPGLPGPVGPPGQ-GFPGVPGGTG
: :::: : :..:. :: : : ::. ::.: :: : : ::: :.:: : :
CCDS14 GFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITL
600 610 620 630 640 650
1920 1930 1940 1950 1960
pF1KB4 P---KGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESS
: :. : .: : :.:: .: :: ::. :
CCDS14 PCIIPGSYGPSGFPGTPGFPGPKGSRGLPGT-P---------------------------
660 670 680
1970 1980 1990 2000 2010 2020
pF1KB4 GSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPP
: :.:: .: ::. : . .: :. : ::. : : ::: :
CCDS14 -----------GQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGL-------P
690 700 710 720
2030 2040 2050 2060 2070 2080
pF1KB4 GPSGLAGEPGKPGIPGLPGRAGGV--GEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG
: .:: : :.::.:: : .: . .: : :::.: .: :..: : .: ::: :. :
CCDS14 GKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHG
730 740 750 760 770 780
2090 2100 2110 2120 2130 2140
pF1KB4 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGP
:: ::: ::.: :: : :.::. :..:: : .: :. : : ::
CCDS14 KPGLLGPK-----------GERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPG-
790 800 810 820 830
2150 2160 2170 2180 2190 2200
pF1KB4 RGQDGNPGLPGERGMAGPEG---KPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP
.:.:: : :: :: : : :: : .: :: : : : ::.::.:: . .::
CCDS14 --ISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGP
840 850 860 870 880 890
2210 2220 2230 2240 2250 2260
pF1KB4 SGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPG-
.: :: : .: :: :: : :. :: : :: .: .::.: : ::. :. :.:: :
CCDS14 KGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGI
900 910 920 930 940 950
2270 2280 2290 2300 2310
pF1KB4 ---RDGASGK--DGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAP
: :. ::.:: : :: :.::: : ::: : : :: :::: : :
CCDS14 PSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPG-----LPGAPGLPGII
960 970 980 990 1000
2320 2330 2340 2350 2360
pF1KB4 GGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPG-P-----KGFKG
:..: : :: : ::::: .: .: .: : ::. : .: .:.:: : :.::
CCDS14 KGVSGK-PGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKG
1010 1020 1030 1040 1050 1060
2370 2380 2390 2400 2410 2420
pF1KB4 DPG--VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLA
: : : . ::::: : :: .: : : : : .::::. .:: :. : ::. ::
CCDS14 DNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGN---KGEDGKVGVSGDVGLP
1070 1080 1090 1100 1110 1120
2430 2440 2450 2460 2470 2480
pF1KB4 GPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPG
: :: :. : : :: ::: : :: : :.: :: ::.: : ::..: .: ::
CCDS14 GAPGFPGVAGMRGEPGLPGSSGHQGA---IGPLGSP--GLIGPKGFPGFPGLHGLNGLPG
1130 1140 1150 1160 1170 1180
2490 2500 2510 2520 2530 2540
pF1KB4 QEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLD
.: .: :: . : : .: : ::.:: .. .: :: : .: ..: ::.
CCDS14 TKGTHGTPGPSIT----GVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRG---QKGDRGFP
1190 1200 1210 1220 1230
2550 2560 2570 2580 2590 2600
pF1KB4 GDKGPRGDNGDPGDKGSK---GEPGDKGSAGLPGLRGLLGPQGQPGAAGIP----GDPGS
: .:: : : :: . . :.::: : :: : :: :: : :: : : :: :.
CCDS14 GLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPG-PSSNQGDTGD
1240 1250 1260 1270 1280 1290
2610 2620 2630 2640 2650 2660
pF1KB4 PGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGE
:: :.:: .: ::: :. : :: :: :.:: : : : :..:::: ::. : ::.
CCDS14 PGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGK
1300 1310 1320 1330 1340 1350
2670 2680 2690 2700 2710
pF1KB4 MGEPGVPGQSGAPGKEGLI-------GPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPG
: : : .: ::. :: : :.:: :: :: : .: : : :.::
CCDS14 AGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPG
1360 1370 1380 1390 1400 1410
2720 2730 2740 2750 2760 2770
pF1KB4 PSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGP
:.:: .: :::::..: : :::: : .: ::.. : :.:: ::. . :
CCDS14 IPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQ--GPFGMPGMPGQSMRVGYTLV
1420 1430 1440 1450 1460 1470
2780 2790 2800 2810 2820 2830
pF1KB4 AGPRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYAADTAGSQLHAVPV
CCDS14 KHSQSEQVPPCPIGMSQLWVGYSLLFVEGQEKAHNQDLGFAGSCLPRFSTMPFIYCNINE
1480 1490 1500 1510 1520 1530
2944 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 19:26:40 2016 done: Sat Nov 5 19:26:42 2016
Total Scan time: 8.660 Total Display time: 2.120
Function used was FASTA [36.3.4 Apr, 2011]