Result of FASTA (omim) for
pF1KB4835
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4835, 478 aa
1>>>pF1KB4835 478 - 478 aa - 478 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1488+/-0.000365; mu= 19.4067+/- 0.023
mean_var=73.7874+/-15.274, 0's: 0 Z-trim(113.4): 12 B-trim: 1340 in 2/52
Lambda= 0.149308
statistics sampled from 22702 (22713) to 22702 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.266), width: 16
Scan time: 9.400
The best scores are: opt bits E(85289)
NP_037408 (OMIM: 605060) sedoheptulokinase [Homo s ( 478) 3185 695.6 7.9e-200
NP_149991 (OMIM: 600148) glycerol kinase 2 [Homo s ( 553) 157 43.4 0.002
NP_000158 (OMIM: 300474,307030) glycerol kinase is ( 524) 147 41.2 0.0084
NP_976325 (OMIM: 300474,307030) glycerol kinase is ( 530) 147 41.2 0.0084
NP_001121599 (OMIM: 300474,307030) glycerol kinase ( 553) 147 41.2 0.0087
NP_001191948 (OMIM: 300474,307030) glycerol kinase ( 559) 147 41.2 0.0088
>>NP_037408 (OMIM: 605060) sedoheptulokinase [Homo sapie (478 aa)
initn: 3185 init1: 3185 opt: 3185 Z-score: 3708.6 bits: 695.6 E(85289): 7.9e-200
Smith-Waterman score: 3185; 100.0% identity (100.0% similar) in 478 aa overlap (1-478:1-478)
10 20 30 40 50 60
pF1KB4 MAARPITLGIDLGTTSVKAALLRAAPDDPSGFAVLASCARAARAEAAVESAVAGPQGREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MAARPITLGIDLGTTSVKAALLRAAPDDPSGFAVLASCARAARAEAAVESAVAGPQGREQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DVSRILQALHECLAALPRPQLRSVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 DVSRILQALHECLAALPRPQLRSVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VSHLVTWQDGRCSSEFLASLPQPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAAGTIHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VSHLVTWQDGRCSSEFLASLPQPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAAGTIHD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 YVVAMLCGLPRPLMSDQNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 YVVAMLCGLPRPLMSDQNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SHMWFEIPKGTQVGVALGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SHMWFEIPKGTQVGVALGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TAPVAYFPYFNRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 TAPVAYFPYFNRTYLGVAASLNGGNVLATFVHMLVQWMADLGLEVEESTVYSRMIQAAVQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 QRDTHLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPIQQLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 QRDTHLTITPTVLGERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSMLPIQQLQ
370 380 390 400 410 420
430 440 450 460 470
pF1KB4 EWGVERVMGSGSALSRNDVLKQEVQRAFPLPMSFGQDVDAAVGAALVMLRRHLNQKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 EWGVERVMGSGSALSRNDVLKQEVQRAFPLPMSFGQDVDAAVGAALVMLRRHLNQKES
430 440 450 460 470
>>NP_149991 (OMIM: 600148) glycerol kinase 2 [Homo sapie (553 aa)
initn: 115 init1: 65 opt: 157 Z-score: 182.6 bits: 43.4 E(85289): 0.002
Smith-Waterman score: 157; 22.5% identity (50.1% similar) in 445 aa overlap (59-465:54-466)
30 40 50 60 70 80
pF1KB4 PSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRILQALHECLAALPRP------QLR
::: ..:::...::.: . ..
NP_149 RFLVFNSKTAELLSHHKVELTQEFPKEGWVEQDPKEILQSVYECIARTCEKLDELNIDIS
30 40 50 60 70 80
90 100 110 120 130
pF1KB4 SVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQDGRCSS---EFLAS
.. ..:::.: . .:.: : :: . . :.: : : .. .. .
NP_149 NIKAVGVSNQRETTVIWDKLTG------------EP--LYNAVVWLDLRTQTTVEDLSKK
90 100 110 120
140 150 160 170 180
pF1KB4 LP------QPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAA----GTIHDYVVAMLCGL
.: . :. : ..: :. . . :.: . :. . . ::: .... : :
NP_149 IPGNSNFVKSKTGLPLSTYFSAVKLRWMLDNVRNVQKAVEEGRALFGTIDSWLIWSLTGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PRPLM--SD-QNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRTSHMWFE
. .: ::. :: .: :. : .:. :::.. . . : . .:
NP_149 VNGGVHCTDVTNASRTMLFNIHSLEWDKELCDFFEIPMDLLPNVFSSSEIYGLIKTGALE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 IPKGTQVGVALGDLQASVYSCMA-QRTDAVLNISTSVQLAASMPSGFQPAQTPDPT-APV
:. .. ::: :.. . : :. .: . .:. : . .: . . . . :
NP_149 ---GVPISGCLGDQCAALVGQMCFQEGQAKNTYGTGCFLLCN--TGRKCVFSEHGLLTTV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 AYFPYFNRTYLGVAASLNGGNVLATFVHMLVQWMAD-LGLEVEESTVYSRMIQAAVQQRD
:: ..: . : :.:. ..: : ..:. : ::. .: : :. . . .
NP_149 AY--KLGREKPAYYA-LEGSVAIAGAV---IRWLRDNLGI-IETSGDIERLAKEVGTSYG
310 320 330 340 350
370 380 390 400 410
pF1KB4 THLTITPTVLG------ERHLPDQLASVTRISSSDLSLGHVTRALCRGIVQNLHSM----
... :. : : : ..:..... . .:.: . :..:
NP_149 CYFV--PAFSGLYAPYWEPSARGILCGLTQFTNKCHIAFAALEAVCFQTREILEAMNRDC
360 370 380 390 400 410
420 430 440 450 460 470
pF1KB4 -LPIQQLQEWGVERVMGSGSALSR--NDVLKQEVQRAFPLPMSFGQDVDAAVGAALVMLR
.:...:: :. : ....: . :.:. : . : .: . . . :.:::
NP_149 GIPLRHLQ---VDGGMTNNKVLMQLQADILHIPVIKPF-MPETTALGAAMAAGAAEGVSV
420 430 440 450 460 470
pF1KB4 RHLNQKES
NP_149 WSLEPQALSVLRMERFEPQIQATESEIRYATWKKAVMKSMGWVTSQSPEGGDPSIFSSLP
480 490 500 510 520 530
>>NP_000158 (OMIM: 300474,307030) glycerol kinase isofor (524 aa)
initn: 111 init1: 71 opt: 147 Z-score: 171.3 bits: 41.2 E(85289): 0.0084
Smith-Waterman score: 158; 25.4% identity (50.9% similar) in 232 aa overlap (59-268:54-268)
30 40 50 60 70 80
pF1KB4 PSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRILQALHECLAALPRP--QLR----
::: ..::....::. . ::
NP_000 RFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILHSVYECIEKTCEKLGQLNIDIS
30 40 50 60 70 80
90 100 110 120 130
pF1KB4 SVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQDGRCSS--EFLAS-
.. .::::.: . .: : : :: . . :.: : : .: : :..
NP_000 NIKAIGVSNQRETTVVWDKITG------------EP--LYNAVVWLDLRTQSTVESLSKR
90 100 110 120
140 150 160 170 180
pF1KB4 LP------QPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAA----GTIHDYVVAMLCGL
.: . :. : ..: :. . . ::: . :. . ::: .... : :
NP_000 IPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLTGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PRPLM--SD-QNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRTSHMWFE
. .: ::. :: .: :. . . :.:...::.. . . : . .:
NP_000 VNGGVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEILPNVRSSSEIYGLMKAGALE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 IPKGTQVGVALGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDPTAPVAY
:. .. ::: .:.. . :
NP_000 ---GVPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAY
250 260 270 280 290 300
>>NP_976325 (OMIM: 300474,307030) glycerol kinase isofor (530 aa)
initn: 111 init1: 71 opt: 147 Z-score: 171.3 bits: 41.2 E(85289): 0.0084
Smith-Waterman score: 158; 26.1% identity (50.0% similar) in 238 aa overlap (59-268:54-274)
30 40 50 60 70 80
pF1KB4 PSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRILQALHECLAALPRP--QLR----
::: ..::....::. . ::
NP_976 RFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILHSVYECIEKTCEKLGQLNIDIS
30 40 50 60 70 80
90 100 110 120 130
pF1KB4 SVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQDGRCSS--EFLAS-
.. .::::.: . .: : : :: . . :.: : : .: : :..
NP_976 NIKAIGVSNQRETTVVWDKITG------------EP--LYNAVVWLDLRTQSTVESLSKR
90 100 110 120
140 150 160 170 180
pF1KB4 LP------QPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAA----GTIHDYVVAMLCGL
.: . :. : ..: :. . . ::: . :. . ::: .... : :
NP_976 IPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLTGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PRPLM--SD-QNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAG--RTSHMW
. .: ::. :: .: :. . . :.:...::.. . . : . ::
NP_976 VNGGVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEILPNVRSSSEIYGLMKISH--
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 FEIPKGTQVGVA----LGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDP
. :. :: ::: .:.. . :
NP_976 -SVKAGALEGVPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGL
250 260 270 280 290 300
>>NP_001121599 (OMIM: 300474,307030) glycerol kinase iso (553 aa)
initn: 111 init1: 71 opt: 147 Z-score: 171.0 bits: 41.2 E(85289): 0.0087
Smith-Waterman score: 158; 25.4% identity (50.9% similar) in 232 aa overlap (59-268:54-268)
30 40 50 60 70 80
pF1KB4 PSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRILQALHECLAALPRP--QLR----
::: ..::....::. . ::
NP_001 RFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILHSVYECIEKTCEKLGQLNIDIS
30 40 50 60 70 80
90 100 110 120 130
pF1KB4 SVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQDGRCSS--EFLAS-
.. .::::.: . .: : : :: . . :.: : : .: : :..
NP_001 NIKAIGVSNQRETTVVWDKITG------------EP--LYNAVVWLDLRTQSTVESLSKR
90 100 110 120
140 150 160 170 180
pF1KB4 LP------QPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAA----GTIHDYVVAMLCGL
.: . :. : ..: :. . . ::: . :. . ::: .... : :
NP_001 IPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLTGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PRPLM--SD-QNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAGRTSHMWFE
. .: ::. :: .: :. . . :.:...::.. . . : . .:
NP_001 VNGGVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEILPNVRSSSEIYGLMKAGALE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 IPKGTQVGVALGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDPTAPVAY
:. .. ::: .:.. . :
NP_001 ---GVPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGLLTTVAY
250 260 270 280 290 300
>>NP_001191948 (OMIM: 300474,307030) glycerol kinase iso (559 aa)
initn: 111 init1: 71 opt: 147 Z-score: 170.9 bits: 41.2 E(85289): 0.0088
Smith-Waterman score: 158; 26.1% identity (50.0% similar) in 238 aa overlap (59-268:54-274)
30 40 50 60 70 80
pF1KB4 PSGFAVLASCARAARAEAAVESAVAGPQGREQDVSRILQALHECLAALPRP--QLR----
::: ..::....::. . ::
NP_001 RFLVFNSKTAELLSHHQVEIKQEFPREGWVEQDPKEILHSVYECIEKTCEKLGQLNIDIS
30 40 50 60 70 80
90 100 110 120 130
pF1KB4 SVVGIGVSGQMHGVVFWKTGQGCEWTEGGITPVFEPRAVSHLVTWQDGRCSS--EFLAS-
.. .::::.: . .: : : :: . . :.: : : .: : :..
NP_001 NIKAIGVSNQRETTVVWDKITG------------EP--LYNAVVWLDLRTQSTVESLSKR
90 100 110 120
140 150 160 170 180
pF1KB4 LP------QPKSHLSVATGFGCATIFWLLKYRPEFLKSYDAA----GTIHDYVVAMLCGL
.: . :. : ..: :. . . ::: . :. . ::: .... : :
NP_001 IPGNNNFVKSKTGLPLSTYFSAVKLRWLLDNVRKVQKAVEEKRALFGTIDSWLIWSLTGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 PRPLM--SD-QNAASWGYFNTQSQSWNVETLRSSGFPVHLLPDIAEPGSVAG--RTSHMW
. .: ::. :: .: :. . . :.:...::.. . . : . ::
NP_001 VNGGVHCTDVTNASRTMLFNIHSLEWDKQLCEFFGIPMEILPNVRSSSEIYGLMKISH--
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 FEIPKGTQVGVA----LGDLQASVYSCMAQRTDAVLNISTSVQLAASMPSGFQPAQTPDP
. :. :: ::: .:.. . :
NP_001 -SVKAGALEGVPISGCLGDQSAALVGQMCFQIGQAKNTYGTGCFLLCNTGHKCVFSDHGL
250 260 270 280 290 300
478 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 06:03:30 2016 done: Sat Nov 5 06:03:31 2016
Total Scan time: 9.400 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]