Result of FASTA (omim) for
pF1KB4832
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4832, 422 aa
1>>>pF1KB4832 422 - 422 aa - 422 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7605+/-0.000356; mu= 14.8246+/- 0.022
mean_var=71.8777+/-13.736, 0's: 0 Z-trim(114.3): 62 B-trim: 0 in 0/51
Lambda= 0.151279
statistics sampled from 24017 (24079) to 24017 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.282), width: 16
Scan time: 9.050
The best scores are: opt bits E(85289)
NP_002552 (OMIM: 602836) P2X purinoceptor 5 isofor ( 422) 2863 634.1 2e-181
NP_001191448 (OMIM: 602836) P2X purinoceptor 5 iso ( 421) 2841 629.3 5.5e-180
NP_001191449 (OMIM: 602836) P2X purinoceptor 5 iso ( 398) 2092 465.8 8.5e-131
NP_778255 (OMIM: 602836) P2X purinoceptor 5 isofor ( 397) 2070 461.0 2.4e-129
NP_002551 (OMIM: 600846) P2X purinoceptor 4 isofor ( 388) 1196 270.3 6.1e-72
NP_001248327 (OMIM: 600846) P2X purinoceptor 4 iso ( 341) 1194 269.8 7.4e-72
NP_005437 (OMIM: 608077) P2X purinoceptor 6 isofor ( 441) 1106 250.7 5.6e-66
XP_016884557 (OMIM: 608077) PREDICTED: P2X purinoc ( 393) 1102 249.8 9.2e-66
XP_011528800 (OMIM: 608077) PREDICTED: P2X purinoc ( 539) 1102 249.8 1.2e-65
NP_001243725 (OMIM: 600846) P2X purinoceptor 4 iso ( 404) 1086 246.3 1.1e-64
NP_002549 (OMIM: 600845,609821) P2X purinoceptor 1 ( 399) 1016 231.0 4.2e-60
NP_777362 (OMIM: 600844,608224) P2X purinoceptor 2 ( 404) 998 227.1 6.4e-59
XP_005266213 (OMIM: 600844,608224) PREDICTED: P2X ( 430) 998 227.1 6.8e-59
XP_016874524 (OMIM: 600844,608224) PREDICTED: P2X ( 462) 998 227.1 7.2e-59
NP_733782 (OMIM: 600844,608224) P2X purinoceptor 2 ( 471) 998 227.1 7.3e-59
XP_005266212 (OMIM: 600844,608224) PREDICTED: P2X ( 488) 998 227.1 7.6e-59
NP_733783 (OMIM: 600844,608224) P2X purinoceptor 2 ( 497) 998 227.1 7.7e-59
NP_001269094 (OMIM: 600844,608224) P2X purinocepto ( 349) 994 226.2 1e-58
NP_001153026 (OMIM: 608077) P2X purinoceptor 6 iso ( 415) 981 223.4 8.6e-58
XP_011528802 (OMIM: 608077) PREDICTED: P2X purinoc ( 513) 977 222.5 1.9e-57
XP_011522201 (OMIM: 600845,609821) PREDICTED: P2X ( 411) 906 207.0 7.2e-53
XP_011522199 (OMIM: 600845,609821) PREDICTED: P2X ( 419) 902 206.1 1.3e-52
XP_005266211 (OMIM: 600844,608224) PREDICTED: P2X ( 512) 879 201.1 5.2e-51
XP_011528804 (OMIM: 608077) PREDICTED: P2X purinoc ( 324) 858 196.5 8.4e-50
XP_016884555 (OMIM: 608077) PREDICTED: P2X purinoc ( 425) 858 196.5 1.1e-49
XP_005261876 (OMIM: 608077) PREDICTED: P2X purinoc ( 473) 858 196.5 1.2e-49
XP_011543371 (OMIM: 600843) PREDICTED: P2X purinoc ( 397) 843 193.2 9.7e-49
XP_011543372 (OMIM: 600843) PREDICTED: P2X purinoc ( 397) 843 193.2 9.7e-49
NP_002550 (OMIM: 600843) P2X purinoceptor 3 [Homo ( 397) 843 193.2 9.7e-49
XP_011543374 (OMIM: 600843) PREDICTED: P2X purinoc ( 323) 833 191.0 3.7e-48
XP_011543373 (OMIM: 600843) PREDICTED: P2X purinoc ( 395) 822 188.7 2.3e-47
XP_011522198 (OMIM: 600845,609821) PREDICTED: P2X ( 431) 792 182.1 2.3e-45
NP_002553 (OMIM: 602566) P2X purinoceptor 7 [Homo ( 595) 788 181.3 5.6e-45
NP_777361 (OMIM: 600844,608224) P2X purinoceptor 2 ( 379) 696 161.1 4.2e-39
NP_057402 (OMIM: 600844,608224) P2X purinoceptor 2 ( 447) 696 161.2 4.9e-39
XP_011533088 (OMIM: 600844,608224) PREDICTED: P2X ( 473) 696 161.2 5.1e-39
XP_016884558 (OMIM: 608077) PREDICTED: P2X purinoc ( 391) 683 158.3 3.1e-38
XP_011536721 (OMIM: 602566) PREDICTED: P2X purinoc ( 491) 653 151.8 3.5e-36
NP_036358 (OMIM: 600844,608224) P2X purinoceptor 2 ( 399) 634 147.6 5.2e-35
XP_016884561 (OMIM: 608077) PREDICTED: P2X purinoc ( 290) 627 146.0 1.1e-34
XP_016884564 (OMIM: 608077) PREDICTED: P2X purinoc ( 290) 627 146.0 1.1e-34
XP_016884562 (OMIM: 608077) PREDICTED: P2X purinoc ( 290) 627 146.0 1.1e-34
XP_016884565 (OMIM: 608077) PREDICTED: P2X purinoc ( 290) 627 146.0 1.1e-34
XP_016884563 (OMIM: 608077) PREDICTED: P2X purinoc ( 290) 627 146.0 1.1e-34
NP_001248326 (OMIM: 600846) P2X purinoceptor 4 iso ( 361) 627 146.1 1.4e-34
XP_011536718 (OMIM: 600846) PREDICTED: P2X purinoc ( 258) 621 144.7 2.6e-34
XP_011528803 (OMIM: 608077) PREDICTED: P2X purinoc ( 388) 623 145.2 2.7e-34
XP_016884559 (OMIM: 608077) PREDICTED: P2X purinoc ( 388) 623 145.2 2.7e-34
XP_016874853 (OMIM: 602566) PREDICTED: P2X purinoc ( 475) 595 139.1 2.2e-32
XP_016874854 (OMIM: 602566) PREDICTED: P2X purinoc ( 475) 595 139.1 2.2e-32
>>NP_002552 (OMIM: 602836) P2X purinoceptor 5 isoform A (422 aa)
initn: 2863 init1: 2863 opt: 2863 Z-score: 3378.3 bits: 634.1 E(85289): 2e-181
Smith-Waterman score: 2863; 100.0% identity (100.0% similar) in 422 aa overlap (1-422:1-422)
10 20 30 40 50 60
pF1KB4 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
370 380 390 400 410 420
pF1KB4 ST
::
NP_002 ST
>>NP_001191448 (OMIM: 602836) P2X purinoceptor 5 isoform (421 aa)
initn: 1480 init1: 1480 opt: 2841 Z-score: 3352.3 bits: 629.3 E(85289): 5.5e-180
Smith-Waterman score: 2841; 99.5% identity (99.8% similar) in 422 aa overlap (1-422:1-421)
10 20 30 40 50 60
pF1KB4 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
:::::::::::::::::::::::: .::::::::::::::::::::::::::::::::::
NP_001 FLKEAEDFTIFIKNHIRFPKFNFS-NNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
190 200 210 220 230
250 260 270 280 290 300
pF1KB4 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB4 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
360 370 380 390 400 410
pF1KB4 ST
::
NP_001 ST
420
>>NP_001191449 (OMIM: 602836) P2X purinoceptor 5 isoform (398 aa)
initn: 2092 init1: 2092 opt: 2092 Z-score: 2469.2 bits: 465.8 E(85289): 8.5e-131
Smith-Waterman score: 2647; 94.3% identity (94.3% similar) in 422 aa overlap (1-422:1-398)
10 20 30 40 50 60
pF1KB4 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE
::::::::::::::::::::::::::::::::::::
NP_001 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQ------------------------
70 80 90
130 140 150 160 170 180
pF1KB4 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB4 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB4 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB4 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB4 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
340 350 360 370 380 390
pF1KB4 ST
::
NP_001 ST
>>NP_778255 (OMIM: 602836) P2X purinoceptor 5 isoform B (397 aa)
initn: 2096 init1: 1480 opt: 2070 Z-score: 2443.3 bits: 461.0 E(85289): 2.4e-129
Smith-Waterman score: 2625; 93.8% identity (94.1% similar) in 422 aa overlap (1-422:1-397)
10 20 30 40 50 60
pF1KB4 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 MGQAGCKGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAE
::::::::::::::::::::::::::::::::::::
NP_778 SLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQ------------------------
70 80 90
130 140 150 160 170 180
pF1KB4 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 NEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSRPEEP
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB4 FLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
:::::::::::::::::::::::: .::::::::::::::::::::::::::::::::::
NP_778 FLKEAEDFTIFIKNHIRFPKFNFS-NNVMDVKDRSFLKSCHFGPKNHYCPIFRLGSVIRW
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB4 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVSSGYNFRFARY
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB4 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 YRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEVRGLEDS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB4 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_778 SQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHR
340 350 360 370 380 390
pF1KB4 ST
::
NP_778 ST
>>NP_002551 (OMIM: 600846) P2X purinoceptor 4 isoform 2 (388 aa)
initn: 1105 init1: 407 opt: 1196 Z-score: 1412.6 bits: 270.3 E(85289): 6.1e-72
Smith-Waterman score: 1246; 50.3% identity (74.0% similar) in 392 aa overlap (4-367:2-388)
10 20 30 40 50
pF1KB4 MGQAGC-KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVD
::: .: ::.: : . :. ...::::. : .: ::::.. :::. .::::..:
NP_002 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETD
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 TSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCA
:. :.: ::::::: :::: :: ::::::::::::: :: .::.::.:.: :: :..:
NP_002 -SVVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 ENEGIPDGA--CSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSR-
: :::.. :..:..: :: : : .:::.::::. .. .. :::. ::::.: ...
NP_002 E---IPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVK-TCEVAAWCPVEDDTHV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB4 PEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPK-NHYCPIFRLG
:. ::: ::.::...::.: .::::::: :.. ..:::: . : . .:::::::
NP_002 PQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 SVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNK-LSKSVSSGYN
.... :: .:::.:.:::..::...:.:.::.::: : :.::: :::.. . ..:: :::
NP_002 KIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYN
240 250 260 270 280 290
300 310 320 330
pF1KB4 FRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK-GAF---------------------FC
::::.:::: :: : :::.::::::::..: :: : : .:
NP_002 FRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLC
300 310 320 330 340 350
340 350 360 370 380 390
pF1KB4 DLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQEL
:....: .::: .::.:::. :. :.. :.
NP_002 DIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ
360 370 380
400 410 420
pF1KB4 QEPPEAKRGSSSQKGNGSVCPQLLEPHRST
>>NP_001248327 (OMIM: 600846) P2X purinoceptor 4 isoform (341 aa)
initn: 1015 init1: 407 opt: 1194 Z-score: 1411.1 bits: 269.8 E(85289): 7.4e-72
Smith-Waterman score: 1194; 54.5% identity (79.0% similar) in 334 aa overlap (4-331:2-330)
10 20 30 40 50
pF1KB4 MGQAGC-KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVD
::: .: ::.: : . :. ...::::. : .: ::::.. :::. .::::..:
NP_001 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETD
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 TSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCA
:. :.: ::::::: :::: :: ::::::::::::: :: .::.::.:.: :: :..:
NP_001 -SVVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 ENEGIPDGA--CSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLETSSR-
: :::.. :..:..: :: : : .:::.::::. .. .. :::. ::::.: ...
NP_001 E---IPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVK-TCEVAAWCPVEDDTHV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB4 PEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPK-NHYCPIFRLG
:. ::: ::.::...::.: .::::::: :.. ..:::: . : . .:::::::
NP_001 PQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLG
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 SVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNK-LSKSVSSGYN
.... :: .:::.:.:::..::...:.:.::.::: : :.::: :::.. . ..:: :::
NP_001 KIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 FRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKKYEEV
::::.:::: :: : :::.::::::::..: ::.. :
NP_001 FRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDITPEKFLESD
300 310 320 330 340
360 370 380 390 400 410
pF1KB4 RGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQ
>>NP_005437 (OMIM: 608077) P2X purinoceptor 6 isoform 1 (441 aa)
initn: 858 init1: 647 opt: 1106 Z-score: 1305.5 bits: 250.7 E(85289): 5.6e-66
Smith-Waterman score: 1156; 44.1% identity (69.6% similar) in 424 aa overlap (2-395:9-423)
10 20 30 40 50
pF1KB4 MGQAGCKGLCLS--LFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLI
:. : : . :.::::::::...: .:: : :::: .:..:.: :..:
NP_005 MCPQLAGAGSMGSPGATTGWGLLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 KKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTP
:::::. : : ..:::.:::. :. ..::.:.:::::.: : :::::::.:::..:::
NP_005 KKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 NQRQNVCAENEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPL
: :. : :. ..: . : : :: ::. : ..:::::.:. .. : ::::..:::.
NP_005 AQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHR-TCEIWSWCPV
130 140 150 160 170
180 190 200 210 220 230
pF1KB4 ETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPK-NHYCP
:.. : .:.: .:..::.:::: . : ::::::::.... : ...: :.. :. . :::
NP_005 ESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 IFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVS
.::.:... ::. :.:.:: :: .:: ..:.:::: . : : ::::: .:..:
NP_005 VFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSF-QLQEK------
240 250 260 270 280 290
300 310 320
pF1KB4 SGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK---------------GA------
.:::: : .. . ::: :::.: ::::::..:.:. ::
NP_005 -SYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVV
300 310 320 330 340 350
330 340 350 360 370 380
pF1KB4 -FFCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDE---ASGLGLSEQL--TSGPGL
:::::.:.:. .. .:: ::::... . ... . : :: :.: : .:.:.
NP_005 TFFCDLLLLYVDREAHFYWRTKYEEAKAPKATANSVWRELALASQARLAECLRRSSAPAP
360 370 380 390 400 410
390 400 410 420
pF1KB4 LGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHRST
. .. : :
NP_005 TATAAGSQTQTPGWPCPSSDTHLPTHSGSL
420 430 440
>>XP_016884557 (OMIM: 608077) PREDICTED: P2X purinocepto (393 aa)
initn: 772 init1: 647 opt: 1102 Z-score: 1301.6 bits: 249.8 E(85289): 9.2e-66
Smith-Waterman score: 1102; 49.2% identity (75.7% similar) in 329 aa overlap (2-327:9-328)
10 20 30 40 50
pF1KB4 MGQAGCKGLCLS--LFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLI
:. : : . :.::::::::...: .:: : :::: .:..:.: :..:
XP_016 MCPQLAGAGSMGSPGATTGWGLLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 KKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTP
:::::. : : ..:::.:::. :. ..::.:.:::::.: : :::::::.:::..:::
XP_016 KKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 NQRQNVCAENEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPL
: :. : :. ..: . : : :: ::. : ..:::::.:. .. : ::::..:::.
XP_016 AQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHR-TCEIWSWCPV
130 140 150 160 170
180 190 200 210 220 230
pF1KB4 ETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPK-NHYCP
:.. : .:.: .:..::.:::: . : ::::::::.... : ...: :.. :. . :::
XP_016 ESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 IFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVS
.::.:... ::. :.:.:: :: .:: ..:.:::: . : : ::::: .:..:
XP_016 VFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSF-QLQEK------
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 SGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKK
.:::: : .. . ::: :::.: ::::::..:.:.
XP_016 -SYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQAKAPKATANSVWRELALASQARL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB4 YEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGS
XP_016 AECLRRSSAPAPTATAAGSQTQTPGWPCPSSDTHLPTHSGSL
360 370 380 390
>>XP_011528800 (OMIM: 608077) PREDICTED: P2X purinocepto (539 aa)
initn: 772 init1: 647 opt: 1102 Z-score: 1299.5 bits: 249.8 E(85289): 1.2e-65
Smith-Waterman score: 1102; 49.2% identity (75.7% similar) in 329 aa overlap (2-327:9-328)
10 20 30 40 50
pF1KB4 MGQAGCKGLCLS--LFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLI
:. : : . :.::::::::...: .:: : :::: .:..:.: :..:
XP_011 MCPQLAGAGSMGSPGATTGWGLLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 KKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTP
:::::. : : ..:::.:::. :. ..::.:.:::::.: : :::::::.:::..:::
XP_011 KKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 NQRQNVCAENEGIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPL
: :. : :. ..: . : : :: ::. : ..:::::.:. .. : ::::..:::.
XP_011 AQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHR-TCEIWSWCPV
130 140 150 160 170
180 190 200 210 220 230
pF1KB4 ETSSRPEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGPK-NHYCP
:.. : .:.: .:..::.:::: . : ::::::::.... : ...: :.. :. . :::
XP_011 ESGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 IFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSKSVS
.::.:... ::. :.:.:: :: .:: ..:.:::: . : : ::::: .:..:
XP_011 VFRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSF-QLQEK------
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 SGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLIKKREFYRDKK
.:::: : .. . ::: :::.: ::::::..:.:.
XP_011 -SYNFRTATHWWEQPGVEARTLLKLYGIRFDILVTGQVGTGREVRAHPHGRHTGHRGSLA
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB4 YEEVRGLEDSSQEAEDEASGLGLSEQLTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGS
XP_011 GRGECEHCGHLQAAVSAADQGVSNACWSLRCLHIESRGAGWGGGRRAGSGAGTWVGPASP
360 370 380 390 400 410
>>NP_001243725 (OMIM: 600846) P2X purinoceptor 4 isoform (404 aa)
initn: 1095 init1: 407 opt: 1086 Z-score: 1282.6 bits: 246.3 E(85289): 1.1e-64
Smith-Waterman score: 1205; 48.3% identity (71.1% similar) in 408 aa overlap (4-367:2-404)
10 20 30 40
pF1KB4 MGQAGC-KGLCLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLV--------------
::: .: ::.: : . :. ...::::. : .: ::::..
NP_001 MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGCYHPHLAEVEMES
10 20 30 40 50
50 60 70 80 90 100
pF1KB4 --VWVFLIKKGYQDVDTSLQSAVITKVKGVAFTNTSDLGQRIWDVADYVIPAQGENVFFV
:::. .::::..: :. :.: ::::::: :::: :: ::::::::::::: :: .::
NP_001 PRRWVFVWEKGYQETD-SVVSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFV
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB4 VTNLIVTPNQRQNVCAENEGIPDGA--CSKDSDCHAGEAVTAGNGVKTGRCLRRENLARG
.::.:.: :: :..: : :::.. :..:..: :: : : .:::.::::. .. ..
NP_001 MTNVILTMNQTQGLCPE---IPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVK-
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB4 TCEIFAWCPLETSSR-PEEPFLKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSC
:::. ::::.: ... :. ::: ::.::...::.: .::::::: :.. ..::::
NP_001 TCEVAAWCPVEDDTHVPQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSC
180 190 200 210 220 230
230 240 250 260 270
pF1KB4 HFGPK-NHYCPIFRLGSVIRWAGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFS
. : . .:::::::.... :: .:::.:.:::..::...:.:.::.::: : :.:::
NP_001 IYDAKTDPFCPIFRLGKIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFR
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB4 RLDNK-LSKSVSSGYNFRFARYYRDAAGVEFRTLMKAYGIRFDVMVNGK-GAF-------
:::.. . ..:: :::::::.:::: :: : :::.::::::::..: :: : :
NP_001 RLDTRDVEHNVSPGYNFRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMI
300 310 320 330 340 350
340 350 360 370
pF1KB4 --------------FCDLVLIYLIKKREFYRDKKYEEVRGLEDSSQEAEDEASGLGLSEQ
.::....: .::: .::.:::. :. :.. :.
NP_001 NIGSGLALLGMATVLCDIIVLYCMKKRLYYREKKYKYVEDYEQGLASELDQ
360 370 380 390 400
380 390 400 410 420
pF1KB4 LTSGPGLLGMPEQQELQEPPEAKRGSSSQKGNGSVCPQLLEPHRST
422 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:33:31 2016 done: Fri Nov 4 20:33:32 2016
Total Scan time: 9.050 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]