Result of FASTA (omim) for
pF1KB4822
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4822, 451 aa
1>>>pF1KB4822 451 - 451 aa - 451 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7296+/-0.000353; mu= 17.7808+/- 0.022
mean_var=119.2315+/-23.731, 0's: 0 Z-trim(117.9): 72 B-trim: 605 in 1/54
Lambda= 0.117457
statistics sampled from 30184 (30265) to 30184 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.355), width: 16
Scan time: 9.710
The best scores are: opt bits E(85289)
NP_002451 (OMIM: 601900,611724) interferon regulat ( 451) 3222 557.0 3.7e-158
NP_001182215 (OMIM: 601900,611724) interferon regu ( 450) 3203 553.8 3.4e-157
XP_006715153 (OMIM: 601900,611724) PREDICTED: inte ( 415) 1562 275.7 1.7e-73
NP_006138 (OMIM: 119300,119500,607199,608864) inte ( 467) 667 124.1 8.1e-28
XP_011514465 (OMIM: 607218,612245,612251) PREDICTE ( 488) 640 119.5 2e-26
XP_011514464 (OMIM: 607218,612245,612251) PREDICTE ( 488) 640 119.5 2e-26
XP_011514466 (OMIM: 607218,612245,612251) PREDICTE ( 488) 640 119.5 2e-26
NP_002154 (OMIM: 601565,614893,614894) interferon ( 426) 638 119.1 2.3e-26
NP_006075 (OMIM: 147574) interferon regulatory fac ( 393) 525 99.9 1.3e-20
NP_116032 (OMIM: 607218,612245,612251) interferon ( 498) 421 82.4 3e-15
NP_001092097 (OMIM: 607218,612245,612251) interfer ( 498) 421 82.4 3e-15
NP_001092100 (OMIM: 607218,612245,612251) interfer ( 498) 421 82.4 3e-15
NP_002190 (OMIM: 147576) interferon regulatory fac ( 349) 406 79.7 1.4e-14
XP_016878688 (OMIM: 601565,614893,614894) PREDICTE ( 222) 399 78.3 2.3e-14
XP_011541680 (OMIM: 147575,211980,613659) PREDICTE ( 284) 382 75.5 2e-13
NP_002189 (OMIM: 147575,211980,613659) interferon ( 325) 382 75.6 2.2e-13
XP_011514463 (OMIM: 607218,612245,612251) PREDICTE ( 504) 384 76.1 2.3e-13
NP_001229381 (OMIM: 607218,612245,612251) interfer ( 412) 378 75.0 4.1e-13
XP_005250374 (OMIM: 607218,612245,612251) PREDICTE ( 514) 378 75.1 4.8e-13
NP_001092099 (OMIM: 607218,612245,612251) interfer ( 514) 378 75.1 4.8e-13
XP_011514462 (OMIM: 607218,612245,612251) PREDICTE ( 514) 378 75.1 4.8e-13
XP_006716037 (OMIM: 607218,612245,612251) PREDICTE ( 514) 378 75.1 4.8e-13
XP_011514460 (OMIM: 607218,612245,612251) PREDICTE ( 514) 378 75.1 4.8e-13
XP_011514461 (OMIM: 607218,612245,612251) PREDICTE ( 514) 378 75.1 4.8e-13
NP_001193625 (OMIM: 119300,119500,607199,608864) i ( 372) 353 70.7 7.2e-12
NP_001184053 (OMIM: 603734,616532) interferon regu ( 300) 347 69.6 1.3e-11
XP_016882256 (OMIM: 603734,616532) PREDICTED: inte ( 427) 347 69.8 1.6e-11
NP_001562 (OMIM: 603734,616532) interferon regulat ( 427) 347 69.8 1.6e-11
XP_016882255 (OMIM: 603734,616532) PREDICTED: inte ( 427) 347 69.8 1.6e-11
NP_001184051 (OMIM: 603734,616532) interferon regu ( 452) 347 69.8 1.7e-11
XP_006723260 (OMIM: 603734,616532) PREDICTED: inte ( 452) 347 69.8 1.7e-11
XP_006723261 (OMIM: 603734,616532) PREDICTED: inte ( 452) 347 69.8 1.7e-11
XP_011518368 (OMIM: 605047,616345) PREDICTED: inte ( 502) 298 61.6 5.7e-09
XP_005252964 (OMIM: 605047,616345) PREDICTED: inte ( 515) 298 61.6 5.8e-09
NP_004020 (OMIM: 605047,616345) interferon regulat ( 474) 290 60.2 1.4e-08
XP_005252966 (OMIM: 605047,616345) PREDICTED: inte ( 487) 290 60.2 1.4e-08
NP_001563 (OMIM: 605047,616345) interferon regulat ( 503) 290 60.2 1.5e-08
XP_005252963 (OMIM: 605047,616345) PREDICTED: inte ( 516) 290 60.2 1.5e-08
NP_004022 (OMIM: 605047,616345) interferon regulat ( 516) 290 60.2 1.5e-08
XP_016873163 (OMIM: 605047,616345) PREDICTED: inte ( 210) 204 45.2 0.0002
NP_001184055 (OMIM: 603734,616532) interferon regu ( 281) 196 44.0 0.00061
NP_001184054 (OMIM: 603734,616532) interferon regu ( 281) 196 44.0 0.00061
NP_001184052 (OMIM: 603734,616532) interferon regu ( 392) 183 42.0 0.0035
XP_006723263 (OMIM: 603734,616532) PREDICTED: inte ( 417) 183 42.0 0.0037
>>NP_002451 (OMIM: 601900,611724) interferon regulatory (451 aa)
initn: 3222 init1: 3222 opt: 3222 Z-score: 2960.5 bits: 557.0 E(85289): 3.7e-158
Smith-Waterman score: 3222; 100.0% identity (100.0% similar) in 451 aa overlap (1-451:1-451)
10 20 30 40 50 60
pF1KB4 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PYKVYRIVPEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRSWRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PYKVYRIVPEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRSWRD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 YVPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPESQAPGVPTEPSIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YVPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPESQAPGVPTEPSIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHTYDASNLDQVLFPYPEDNGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHTYDASNLDQVLFPYPEDNGQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCKLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 RKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCKLFD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 TQQFLSELQAFAHHGRSLPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TQQFLSELQAFAHHGRSLPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQN
370 380 390 400 410 420
430 440 450
pF1KB4 SGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
:::::::::::::::::::::::::::::::
NP_002 SGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
430 440 450
>>NP_001182215 (OMIM: 601900,611724) interferon regulato (450 aa)
initn: 2073 init1: 2073 opt: 3203 Z-score: 2943.1 bits: 553.8 E(85289): 3.4e-157
Smith-Waterman score: 3203; 99.8% identity (99.8% similar) in 451 aa overlap (1-451:1-450)
10 20 30 40 50 60
pF1KB4 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PYKVYRIVPEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRSWRD
:::::::::::::::::::::::::::::::::::::::::::: :::::::::::::::
NP_001 PYKVYRIVPEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQ-VHNYMMPPLDRSWRD
130 140 150 160 170
190 200 210 220 230 240
pF1KB4 YVPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPESQAPGVPTEPSIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPESQAPGVPTEPSIR
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 SAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHTYDASNLDQVLFPYPEDNGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHTYDASNLDQVLFPYPEDNGQ
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 RKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCKLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCKLFD
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB4 TQQFLSELQAFAHHGRSLPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TQQFLSELQAFAHHGRSLPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQN
360 370 380 390 400 410
430 440 450
pF1KB4 SGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
:::::::::::::::::::::::::::::::
NP_001 SGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
420 430 440 450
>>XP_006715153 (OMIM: 601900,611724) PREDICTED: interfer (415 aa)
initn: 1560 init1: 1560 opt: 1562 Z-score: 1440.7 bits: 275.7 E(85289): 1.7e-73
Smith-Waterman score: 2892; 92.0% identity (92.0% similar) in 451 aa overlap (1-451:1-415)
10 20 30 40 50 60
pF1KB4 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PYKVYRIVPEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRSWRD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PYKVYRIVPEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRSWRD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 YVPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPESQAPGVPTEPSIR
::::::::::::::::::::::::::::::::
XP_006 YVPDQPHPEIPYQCPMTFGPRGHHWQGPACEN----------------------------
190 200 210
250 260 270 280 290 300
pF1KB4 SAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHTYDASNLDQVLFPYPEDNGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 --------DCRLHICLYYREILVKELTTSSPEGCRISHGHTYDASNLDQVLFPYPEDNGQ
220 230 240 250 260
310 320 330 340 350 360
pF1KB4 RKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCKLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCKLFD
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB4 TQQFLSELQAFAHHGRSLPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TQQFLSELQAFAHHGRSLPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQN
330 340 350 360 370 380
430 440 450
pF1KB4 SGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
:::::::::::::::::::::::::::::::
XP_006 SGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
390 400 410
>>NP_006138 (OMIM: 119300,119500,607199,608864) interfer (467 aa)
initn: 675 init1: 397 opt: 667 Z-score: 620.4 bits: 124.1 E(85289): 8.1e-28
Smith-Waterman score: 803; 33.9% identity (60.9% similar) in 445 aa overlap (23-438:9-427)
10 20 30 40 50 60
pF1KB4 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
.:. ::. :.::: ::::.: ..... :.:::::: ..
NP_006 MALHPRRVRLKPWLVAQVDSGLYPGLIWLHRDSKRFQIPWKHATRH
10 20 30 40
70 80 90 100 110 120
pF1KB4 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
. ..::. ..:::::. ::..::.: ::: ::..:::::::: .:. . . .. .
NP_006 SPQQEEENTIFKAWAVETGKYQEGVDDPDPAKWKAQLRCALNKSREFNLMYDGTKEVPMN
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB4 PYKVYRIVPEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRSWRD
: :.:.. . .:: :. .: . : : .. : .:. ..
NP_006 PVKIYQVC-----------DIPQPQGSIINPGST----GSAPWDEKDN----DVDEEDEE
110 120 130 140
190 200 210 220 230
pF1KB4 YVPDQPHPEIPYQCPMTFGPRGHHWQGPA----CENG-CQVTGTFYACAPPESQAPGVPT
:: . ..: : . : . ..:: : : :. ... : : ..: .:
NP_006 DELDQSQHHVPIQDTFPFLNINGSPMAPASVGNCSVGNCSPEAVWPKTEPLEMEVPQAPI
150 160 170 180 190 200
240 250 260 270 280
pF1KB4 EPSIRSAE----ALAFSDCRLHICLYYR-EILVKELTTSSPEGCRISHG---------HT
.: : : .: ..: : : . :: . . .:.:.:.:::. .: .
NP_006 QPFYSSPELWISSLPMTD--LDIKFQYRGKEYGQTMTVSNPQGCRLFYGDLGPMPDQEEL
210 220 230 240 250 260
290 300 310 320 330
pF1KB4 YDASNLDQVLFPYPE---DNGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDG
. .:.:: :: :: .. :. :::. ..::..: .. ..:: :::: ..::.:
NP_006 FGPVSLEQVKFPGPEHITNEKQKLFTSKLLDVMDRGLILEVSGHAIYAIRLCQCKVYWSG
270 280 290 300 310 320
340 350 360 370 380 390
pF1KB4 PLALCNDRPNKLERDQTCKLFDTQQFLSELQAFAHHGRSL---PRFQVTLCFGEEFPDPQ
: : :: .::.. ::: . :::.: .::. .. : :.. ::::::.:: .
NP_006 PCAPSLVAPNLIERQKKVKLFCLETFLSDL--IAHQKGQIEKQPPFEIYLCFGEEWPDGK
330 340 350 360 370 380
400 410 420 430 440 450
pF1KB4 R-QRKLITAHVEPLLARQLYYFAQQNSGHFLRGYD---LPEHISNPEDYHRSIRHSSIQE
.:::: ..: :..::..: .. :: : :..: . .::.:.
NP_006 PLERKLILVQVIPVVARMIY---EMFSGDFTRSFDSGSVRLQISTPDIKDNIVAQLKQLY
390 400 410 420 430 440
NP_006 RILQTQESWQPMQPTPSMQLPPALPPQ
450 460
>>XP_011514465 (OMIM: 607218,612245,612251) PREDICTED: i (488 aa)
initn: 730 init1: 377 opt: 640 Z-score: 595.4 bits: 119.5 E(85289): 2e-26
Smith-Waterman score: 761; 33.6% identity (57.1% similar) in 455 aa overlap (23-446:16-447)
10 20 30 40 50 60
pF1KB4 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
.:. ::. :..: .:::: : : ::..: :::.:: ..
XP_011 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRH
10 20 30 40 50
70 80 90 100 110
pF1KB4 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDIS-
... : ..::::: ::. ::.:. :: ::. :::::::: ::. :. . :.
XP_011 GPSQDGDNTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFR-LIYDGPRDMPP
60 70 80 90 100 110
120 130 140 150 160
pF1KB4 DPYKVYRIV-----------PEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHN
.:::.:.. :: . :: . :. ... : : . :
XP_011 QPYKIYEVCSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPP
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB4 YMMPPLDRSWRDYVPDQPHPEIPYQCPMTFGPRG-HHWQGPACENGCQVTGTFYACAPP-
..::. : : :. : .: : .. . . : : . : ::
XP_011 TLQPPV-------VLGPPAPDPSPLAPPPGNPAGFRELLSEVLE-----PGPLPASLPPA
180 190 200 210 220
230 240 250 260 270 280
pF1KB4 -ESQAPGVPTEPSIRSAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHT----
:. : . : . : ..: :.: . :: . :: :.:.:::. ...
XP_011 GEQLLPDLLISPHM-----LPLTD--LEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQ
230 240 250 260 270
290 300 310 320 330
pF1KB4 -----YDASNLDQVLFPYPED---NGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSR
. .:.:: :: ::: . :: ..::. :.::..: . . ::: :::: .
XP_011 EQVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCK
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB4 IYWDGPLALCNDR-PNKLERDQTCKLFDTQQFLSELQAFAH-HGRSLPRFQVTLCFGEEF
..:.:: : .: :: ..:. :::. ..::.:: : . . . : :.. .:::::.
XP_011 VFWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEW
340 350 360 370 380 390
400 410 420 430 440
pF1KB4 PDPQ-RQRKLITAHVEPLLARQLYYFAQQNSGHFLRGYD-LPEHISNPEDYHRSIRHSSI
:: . :..::::..: :. :: : .. ::.. . : . .::::. : ...
XP_011 PDRKPREKKLITVQVVPVAARLLL---EMFSGELSWSADSIRLQISNPDLKDRMVEQFKE
400 410 420 430 440 450
450
pF1KB4 QE
XP_011 LHHIWQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ
460 470 480
>>XP_011514464 (OMIM: 607218,612245,612251) PREDICTED: i (488 aa)
initn: 730 init1: 377 opt: 640 Z-score: 595.4 bits: 119.5 E(85289): 2e-26
Smith-Waterman score: 761; 33.6% identity (57.1% similar) in 455 aa overlap (23-446:16-447)
10 20 30 40 50 60
pF1KB4 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
.:. ::. :..: .:::: : : ::..: :::.:: ..
XP_011 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRH
10 20 30 40 50
70 80 90 100 110
pF1KB4 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDIS-
... : ..::::: ::. ::.:. :: ::. :::::::: ::. :. . :.
XP_011 GPSQDGDNTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFR-LIYDGPRDMPP
60 70 80 90 100 110
120 130 140 150 160
pF1KB4 DPYKVYRIV-----------PEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHN
.:::.:.. :: . :: . :. ... : : . :
XP_011 QPYKIYEVCSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPP
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB4 YMMPPLDRSWRDYVPDQPHPEIPYQCPMTFGPRG-HHWQGPACENGCQVTGTFYACAPP-
..::. : : :. : .: : .. . . : : . : ::
XP_011 TLQPPV-------VLGPPAPDPSPLAPPPGNPAGFRELLSEVLE-----PGPLPASLPPA
180 190 200 210 220
230 240 250 260 270 280
pF1KB4 -ESQAPGVPTEPSIRSAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHT----
:. : . : . : ..: :.: . :: . :: :.:.:::. ...
XP_011 GEQLLPDLLISPHM-----LPLTD--LEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQ
230 240 250 260 270
290 300 310 320 330
pF1KB4 -----YDASNLDQVLFPYPED---NGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSR
. .:.:: :: ::: . :: ..::. :.::..: . . ::: :::: .
XP_011 EQVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCK
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB4 IYWDGPLALCNDR-PNKLERDQTCKLFDTQQFLSELQAFAH-HGRSLPRFQVTLCFGEEF
..:.:: : .: :: ..:. :::. ..::.:: : . . . : :.. .:::::.
XP_011 VFWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEW
340 350 360 370 380 390
400 410 420 430 440
pF1KB4 PDPQ-RQRKLITAHVEPLLARQLYYFAQQNSGHFLRGYD-LPEHISNPEDYHRSIRHSSI
:: . :..::::..: :. :: : .. ::.. . : . .::::. : ...
XP_011 PDRKPREKKLITVQVVPVAARLLL---EMFSGELSWSADSIRLQISNPDLKDRMVEQFKE
400 410 420 430 440 450
450
pF1KB4 QE
XP_011 LHHIWQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ
460 470 480
>>XP_011514466 (OMIM: 607218,612245,612251) PREDICTED: i (488 aa)
initn: 730 init1: 377 opt: 640 Z-score: 595.4 bits: 119.5 E(85289): 2e-26
Smith-Waterman score: 761; 33.6% identity (57.1% similar) in 455 aa overlap (23-446:16-447)
10 20 30 40 50 60
pF1KB4 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
.:. ::. :..: .:::: : : ::..: :::.:: ..
XP_011 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRH
10 20 30 40 50
70 80 90 100 110
pF1KB4 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDIS-
... : ..::::: ::. ::.:. :: ::. :::::::: ::. :. . :.
XP_011 GPSQDGDNTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFR-LIYDGPRDMPP
60 70 80 90 100 110
120 130 140 150 160
pF1KB4 DPYKVYRIV-----------PEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHN
.:::.:.. :: . :: . :. ... : : . :
XP_011 QPYKIYEVCSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPP
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB4 YMMPPLDRSWRDYVPDQPHPEIPYQCPMTFGPRG-HHWQGPACENGCQVTGTFYACAPP-
..::. : : :. : .: : .. . . : : . : ::
XP_011 TLQPPV-------VLGPPAPDPSPLAPPPGNPAGFRELLSEVLE-----PGPLPASLPPA
180 190 200 210 220
230 240 250 260 270 280
pF1KB4 -ESQAPGVPTEPSIRSAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHT----
:. : . : . : ..: :.: . :: . :: :.:.:::. ...
XP_011 GEQLLPDLLISPHM-----LPLTD--LEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQ
230 240 250 260 270
290 300 310 320 330
pF1KB4 -----YDASNLDQVLFPYPED---NGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSR
. .:.:: :: ::: . :: ..::. :.::..: . . ::: :::: .
XP_011 EQVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCK
280 290 300 310 320 330
340 350 360 370 380 390
pF1KB4 IYWDGPLALCNDR-PNKLERDQTCKLFDTQQFLSELQAFAH-HGRSLPRFQVTLCFGEEF
..:.:: : .: :: ..:. :::. ..::.:: : . . . : :.. .:::::.
XP_011 VFWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEW
340 350 360 370 380 390
400 410 420 430 440
pF1KB4 PDPQ-RQRKLITAHVEPLLARQLYYFAQQNSGHFLRGYD-LPEHISNPEDYHRSIRHSSI
:: . :..::::..: :. :: : .. ::.. . : . .::::. : ...
XP_011 PDRKPREKKLITVQVVPVAARLLL---EMFSGELSWSADSIRLQISNPDLKDRMVEQFKE
400 410 420 430 440 450
450
pF1KB4 QE
XP_011 LHHIWQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ
460 470 480
>>NP_002154 (OMIM: 601565,614893,614894) interferon regu (426 aa)
initn: 1103 init1: 388 opt: 638 Z-score: 594.3 bits: 119.1 E(85289): 2.3e-26
Smith-Waterman score: 1040; 45.6% identity (63.7% similar) in 421 aa overlap (20-422:6-386)
10 20 30 40 50 60
pF1KB4 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
:. .::::::.::::. ::::.:::::::.:::::::::::
NP_002 MCDRNGGRRLRQWLIEQIDSSMYPGLIWENEEKSMFRIPWKHAGKQ
10 20 30 40
70 80 90 100 110 120
pF1KB4 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
:::.: ::..:::::.:::::.:: :: .: ::::::::::::: ::::...:::::::.
NP_002 DYNQEVDASIFKAWAVFKGKFKEG-DKAEPATWKTRLRCALNKSPDFEEVTDRSQLDISE
50 60 70 80 90 100
130 140 150 160 170
pF1KB4 PYKVYRIVPEGAKK---GAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRS
:::::::::: .: :. . : . . :. : .::
NP_002 PYKVYRIVPEEEQKCKLGVATAGCVNEVTEMECGRSEIDELIKEPS--VDDYM-------
110 120 130 140 150
180 190 200 210 220 230
pF1KB4 WRDYVPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPESQAPGVP--T
.. .: : : : . : : .: : . ::: :
NP_002 --GMIKRSPSP--PEACRSQLLP---DW---------------WAQQP----STGVPLVT
160 170 180 190
240 250 260 270 280
pF1KB4 EPSIRSAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHT-------YDASNLD
. .:. ::: .. : .:: :: . ::. :::::.: .. : .:.
NP_002 GYTTYDAHHSAFS--QMVISFYYGGKLVGQATTTCPEGCRLSLSQPGLPGTKLYGPEGLE
200 210 220 230 240
290 300 310 320 330 340
pF1KB4 QVLFPYPED----NGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCN
: :: : : . ::. .::..::::::.: . .:...:::::.:.. .: ..:.
NP_002 LVRFP-PADAIPSERQRQVTRKLFGHLERGVLLHSSRQGVFVKRLCQGRVFCSGNAVVCK
250 260 270 280 290 300
350 360 370 380 390 400
pF1KB4 DRPNKLERDQTCKLFDTQQFLSELQAFAHHGRSLPRFQVTLCFGEEFPD--PQRQRKLIT
::::::::.. ..:::.::. ::: : . :: .:.::::::::: : :. :::
NP_002 GRPNKLERDEVVQVFDTSQFFRELQQFYNSQGRLPDGRVVLCFGEEFPDMAPLRS-KLIL
310 320 330 340 350 360
410 420 430 440 450
pF1KB4 AHVEPLLARQLYYFAQQNSGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
...: : .::: : .. :
NP_002 VQIEQLYVRQLAEEAGKSCGAGSVMQAPEEPPPDQVFRMFPDICASHQRSFFRENQQITV
370 380 390 400 410 420
>>NP_006075 (OMIM: 147574) interferon regulatory factor (393 aa)
initn: 741 init1: 328 opt: 525 Z-score: 491.2 bits: 99.9 E(85289): 1.3e-20
Smith-Waterman score: 738; 34.4% identity (61.3% similar) in 395 aa overlap (23-413:11-378)
10 20 30 40 50 60
pF1KB4 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
:::.:...:..::..::. :.. :..:::::::::::
NP_006 MASGRARCTRKLRNWVVEQVESGQFPGVCWDDTAKTMFRIPWKHAGKQ
10 20 30 40
70 80 90 100 110 120
pF1KB4 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISD
:. ...:::.:::::.::::..:: : : .::::::::::::..:.:. ::...:...
NP_006 DFREDQDAAFFKAWAIFKGKYKEG-DTGGPAVWKTRLRCALNKSSEFKEVPERGRMDVAE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB4 PYKVYRIVPEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHNYMMPPLDRSWRD
:::::...: : .: .: :. ..:... :. . . .:
NP_006 PYKVYQLLPPGIVSG--------------QPGTQ-----KVPSKRQHSSVSSE-RKEEED
110 120 130 140
190 200 210 220 230
pF1KB4 YVPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPPE-SQAPGVPTEPSI
. . : .. .: .: : .. ... . : : ... .: . .
NP_006 AMQNCTLSPSVLQDSLNNEEEGA--SGGAVHSDIGSSSSSSSPEPQEVTDTTEAPFQGDQ
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB4 RSAEAL--AFSDCRLHICLYYREILVKELTTSSPEGCRISHGHTYDASNLDQVLFPYPED
:: : : : : . . : .: : ..: . ::. . . :...::::: :
NP_006 RSLEFLLPPEPDYSLLLTFIYNGRVVGEAQVQSLD-CRLVAEPSGSESSMEQVLFPKP--
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB4 NGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRIYWDGPLALCNDRPNKLERDQTCK
: . ..:::.::::... : ::...::: : :..: : . :. : .. .
NP_006 -GPLEPTQRLLSQLERGILVASNPRGLFVQRLCPIPISWNAPQAPPGPGPHLLPSNECVE
270 280 290 300 310 320
360 370 380 390 400 410
pF1KB4 LFDTQQFLSELQAFAHHGRSLPRFQVTLCFGEE-FPDPQRQRKLITAHVEPLLARQLYYF
:: : : .: . . :.::::: : :: . . ..:::...: .:: :
NP_006 LFRTAYFCRDLVRYFQGLGPPPKFQVTLNFWEESHGSSHTPQNLITVKMEQAFARYLLEQ
330 340 350 360 370 380
420 430 440 450
pF1KB4 AQQNSGHFLRGYDLPEHISNPEDYHRSIRHSSIQE
NP_006 TPEQQAAILSLV
390
>>NP_116032 (OMIM: 607218,612245,612251) interferon regu (498 aa)
initn: 730 init1: 377 opt: 421 Z-score: 394.8 bits: 82.4 E(85289): 3e-15
Smith-Waterman score: 767; 33.5% identity (56.4% similar) in 454 aa overlap (23-446:16-457)
10 20 30 40 50 60
pF1KB4 MNLEGGGRGGEFGMSAVSCGNGKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQ
.:. ::. :..: .:::: : : ::..: :::.:: ..
NP_116 MNQSIPVAPTPPRRVRLKPWLVAQVNSCQYPGLQWVNGEKKLFCIPWRHATRH
10 20 30 40 50
70 80 90 100 110
pF1KB4 DYNREEDAALFKAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDIS-
... : ..::::: ::. ::.:. :: ::. :::::::: ::. :. . :.
NP_116 GPSQDGDNTIFKAWAKETGKYTEGVDEADPAKWKANLRCALNKSRDFR-LIYDGPRDMPP
60 70 80 90 100 110
120 130 140 150 160
pF1KB4 DPYKVYRIV-----------PEGAKKGAKQLTLEDPQMSMSHPYTMTTPYPSLPAQQVHN
.:::.:.. :: . :: . :. ... : : . :
NP_116 QPYKIYEVCSNGPAPTDSQPPEDYSFGAGEEEEEEEELQRMLPSLSLTEDVKWPPTLQPP
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB4 YMMPPLDRSWRDYVPDQPHPEIPYQCPMTFGPRGHHWQGPACENGCQVTGTFYACAPP--
. :: . : : : :.. : :. . : . : ::
NP_116 TLRPPTLQPPTLQPPVVLGPPAPDPSPLA-PPPGNPAGFRELLSEVLEPGPLPASLPPAG
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB4 ESQAPGVPTEPSIRSAEALAFSDCRLHICLYYREILVKELTTSSPEGCRISHGHT-----
:. : . : . : ..: :.: . :: . :: :.:.:::. ...
NP_116 EQLLPDLLISPHM-----LPLTD--LEIKFQYRGRPPRALTISNPHGCRLFYSQLEATQE
240 250 260 270 280
290 300 310 320 330
pF1KB4 ----YDASNLDQVLFPYPED---NGQRKNIEKLLSHLERGVVLWMAPDGLYAKRLCQSRI
. .:.:: :: ::: . :: ..::. :.::..: . . ::: :::: ..
NP_116 QVELFGPISLEQVRFPSPEDIPSDKQRFYTNQLLDVLDRGLILQLQGQDLYAIRLCQCKV
290 300 310 320 330 340
340 350 360 370 380 390
pF1KB4 YWDGPLALCNDR-PNKLERDQTCKLFDTQQFLSELQAFAH-HGRSLPRFQVTLCFGEEFP
.:.:: : .: :: ..:. :::. ..::.:: : . . . : :.. .:::::.:
NP_116 FWSGPCASAHDSCPNPIQREVKTKLFSLEHFLNELILFQKGQTNTPPPFEIFFCFGEEWP
350 360 370 380 390 400
400 410 420 430 440 450
pF1KB4 DPQ-RQRKLITAHVEPLLARQLYYFAQQNSGHFLRGYD-LPEHISNPEDYHRSIRHSSIQ
: . :..::::..: :. :: : .. ::.. . : . .::::. : ...
NP_116 DRKPREKKLITVQVVPVAARLLL---EMFSGELSWSADSIRLQISNPDLKDRMVEQFKEL
410 420 430 440 450 460
pF1KB4 E
NP_116 HHIWQSQQRLQPVAQAPPGAGLGVGQGPWPMHPAGMQ
470 480 490
451 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:15:28 2016 done: Fri Nov 4 03:15:29 2016
Total Scan time: 9.710 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]