Result of FASTA (omim) for
pF1KB4809
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4809, 734 aa
1>>>pF1KB4809 734 - 734 aa - 734 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3615+/-0.000437; mu= 20.2791+/- 0.027
mean_var=79.2681+/-15.714, 0's: 0 Z-trim(110.7): 31 B-trim: 0 in 0/53
Lambda= 0.144054
statistics sampled from 19093 (19118) to 19093 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.581), E-opt: 0.2 (0.224), width: 16
Scan time: 10.600
The best scores are: opt bits E(85289)
NP_006730 (OMIM: 602696) DNA replication licensing ( 734) 4810 1010.1 0
XP_006724305 (OMIM: 602696) PREDICTED: DNA replica ( 732) 4590 964.4 0
NP_005905 (OMIM: 602638,609981) DNA replication li ( 863) 1087 236.4 3.7e-61
NP_877423 (OMIM: 602638,609981) DNA replication li ( 863) 1087 236.4 3.7e-61
NP_001265524 (OMIM: 600592) DNA replication licens ( 543) 981 214.2 1.1e-54
NP_877577 (OMIM: 600592) DNA replication licensing ( 543) 981 214.2 1.1e-54
XP_005250405 (OMIM: 600592) PREDICTED: DNA replica ( 612) 981 214.3 1.2e-54
XP_016867706 (OMIM: 600592) PREDICTED: DNA replica ( 612) 981 214.3 1.2e-54
NP_005907 (OMIM: 600592) DNA replication licensing ( 719) 981 214.3 1.4e-54
NP_005906 (OMIM: 223100,601806) DNA replication li ( 821) 882 193.8 2.3e-48
NP_001257401 (OMIM: 602693) DNA replication licens ( 818) 856 188.4 9.9e-47
NP_002379 (OMIM: 602693) DNA replication licensing ( 853) 856 188.4 1e-46
NP_004517 (OMIM: 116945,616968) DNA replication li ( 904) 827 182.4 7e-45
NP_060166 (OMIM: 610098,616185) DNA helicase MCM9 (1143) 762 169.0 9.8e-41
XP_016883595 (OMIM: 608187,612885) PREDICTED: DNA ( 776) 695 154.9 1.1e-36
NP_001268449 (OMIM: 608187,612885) DNA helicase MC ( 840) 695 154.9 1.2e-36
NP_115874 (OMIM: 608187,612885) DNA helicase MCM8 ( 840) 695 154.9 1.2e-36
XP_016883596 (OMIM: 608187,612885) PREDICTED: DNA ( 557) 628 140.9 1.4e-32
XP_011527689 (OMIM: 608187,612885) PREDICTED: DNA ( 581) 597 134.5 1.2e-30
NP_877954 (OMIM: 608187,612885) DNA helicase MCM8 ( 824) 582 131.5 1.4e-29
NP_001268450 (OMIM: 608187,612885) DNA helicase MC ( 880) 529 120.5 3e-26
XP_016883594 (OMIM: 608187,612885) PREDICTED: DNA ( 880) 529 120.5 3e-26
NP_001268451 (OMIM: 608187,612885) DNA helicase MC ( 793) 410 95.7 7.7e-19
NP_694987 (OMIM: 610098,616185) DNA helicase MCM9 ( 391) 402 93.8 1.4e-18
>>NP_006730 (OMIM: 602696) DNA replication licensing fac (734 aa)
initn: 4810 init1: 4810 opt: 4810 Z-score: 5401.7 bits: 1010.1 E(85289): 0
Smith-Waterman score: 4810; 100.0% identity (100.0% similar) in 734 aa overlap (1-734:1-734)
10 20 30 40 50 60
pF1KB4 MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 VSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 DRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 EGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGE
670 680 690 700 710 720
730
pF1KB4 IQHRMQRKVLYRLK
::::::::::::::
NP_006 IQHRMQRKVLYRLK
730
>>XP_006724305 (OMIM: 602696) PREDICTED: DNA replication (732 aa)
initn: 4590 init1: 4590 opt: 4590 Z-score: 5154.6 bits: 964.4 E(85289): 0
Smith-Waterman score: 4590; 100.0% identity (100.0% similar) in 701 aa overlap (1-701:1-701)
10 20 30 40 50 60
pF1KB4 MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSGEEV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGLTTSRGRDRVGVGIRSSYIRVLGIQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RCSVLAAANSVFGRWDETKGEDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLH
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 VSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 EGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGE
:::::::::::::::::::::::::::::::::::::::::
XP_006 EGFTSQEDQEMLSRIEKQLKRRFAIGSQVSEHSIIKDFTKQLSLLSGQAKASETETDRDR
670 680 690 700 710 720
730
pF1KB4 IQHRMQRKVLYRLK
XP_006 DERQTELETAIE
730
>>NP_005905 (OMIM: 602638,609981) DNA replication licens (863 aa)
initn: 951 init1: 520 opt: 1087 Z-score: 1219.1 bits: 236.4 E(85289): 3.7e-61
Smith-Waterman score: 1134; 34.7% identity (61.9% similar) in 680 aa overlap (26-679:161-808)
10 20 30 40 50
pF1KB4 MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFL-----RQYRVGTDRTG
: : ..:: ...:. .. :: : :
NP_005 SDGAAAEDIVASEQSLGQKLVIWGTDVNVAACKENFQRFLQRFIDPLAKEEENVGIDITE
140 150 160 170 180 190
60 70 80 90 100 110
pF1KB4 FTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEV
. : : . .:: ...:. : . :::..: : . : : . .. : ..:.
NP_005 PLYMQR--LGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMA----VNEI
200 210 220 230 240
120 130 140 150 160 170
pF1KB4 TRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISI
: . ..::: . . ...:.:. . ...:. : :..: .: . . . .
NP_005 FFDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFF
250 260 270 280 290 300
180 190 200 210 220
pF1KB4 QCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKC-PLDPYFIMPDKCKCVDFQTLKL
::. : .: : . : : : : : :: : . .. .. : : .::
NP_005 QCQVCAHT-TRVEMDRGR--IAEPSVC-----GR--CHTTHSMALIHNRSLFSDKQMIKL
310 320 330 340 350
230 240 250 260 270 280
pF1KB4 QELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGL----TTSRGRDRV
:: :. .: :. :. . :. : ::: ::.::.. ::: . . .. .. ..
NP_005 QESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKT
360 370 380 390 400 410
290 300 310 320 330 340
pF1KB4 GVGI----RSSYIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAP
. . ... :. :. : .. . : : .. : ...:. :..:: .....::
NP_005 HIDVIHYRKTDAKRLHGL--DEEAEQKLF----SEKRVELLKELSRKPDIYERLASALAP
420 430 440 450 460
350 360 370 380 390
pF1KB4 SIFGGTDMKKAIACLLFGGSRKRLPD-GLTR-RGDINLLMLGDPGTAKSQLLKFVEKCSP
::. :.::.: ::::.:: . : . :..::.:. :::::.:::::..: . :
NP_005 SIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVP
470 480 490 500 510 520
400 410 420 430 440 450
pF1KB4 IGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIH
: :::::::::.:::: ::.:: .:..... ::.::.:.:. :::::::: :. : ..:
NP_005 RGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLH
530 540 550 560 570 580
460 470 480 490 500 510
pF1KB4 EAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKGE-DNIDFMPTILSRFDMIF
:.:::::.::::::: ::.: ::::::: . ..:. : .::.. :.:::::.::
NP_005 EVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIF
590 600 610 620 630 640
520 530 540 550 560 570
pF1KB4 IVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEA
.. : ..: : ::.:...:. . .. :: : .:.: :: .::: . :::: ::
NP_005 LLLDPQDEAYDRRLAHHLVALYYQ--SEEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEA
650 660 670 680 690 700
580 590 600 610 620 630
pF1KB4 AEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVE
.. : . :. :: . .. :. . ::::...:.::: .:..:. . :::
NP_005 SQALIEAYVDMR-------KIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVE
710 720 730 740 750
640 650 660 670 680
pF1KB4 EALRLFQVSTLDAA---------LSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQV
:: :: . . ..: .: .:. . ::.. .: :.. :.:
NP_005 EAKRLHREALKQSATDPRTGIVDISILTTGMSA-TSRKRKEELAEALKKLILSKGKTPAL
760 770 780 790 800 810
690 700 710 720 730
pF1KB4 SEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRKVLYRLK
NP_005 KYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTGKTVRLL
820 830 840 850 860
>>NP_877423 (OMIM: 602638,609981) DNA replication licens (863 aa)
initn: 951 init1: 520 opt: 1087 Z-score: 1219.1 bits: 236.4 E(85289): 3.7e-61
Smith-Waterman score: 1134; 34.7% identity (61.9% similar) in 680 aa overlap (26-679:161-808)
10 20 30 40 50
pF1KB4 MSGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFL-----RQYRVGTDRTG
: : ..:: ...:. .. :: : :
NP_877 SDGAAAEDIVASEQSLGQKLVIWGTDVNVAACKENFQRFLQRFIDPLAKEEENVGIDITE
140 150 160 170 180 190
60 70 80 90 100 110
pF1KB4 FTFKYRDELKRHYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEV
. : : . .:: ...:. : . :::..: : . : : . .. : ..:.
NP_877 PLYMQR--LGEINVIGEPFLNVNCEHIKSFDKNLYRQLISYPQEVIPTFDMA----VNEI
200 210 220 230 240
120 130 140 150 160 170
pF1KB4 TRPRPSGEEVLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISI
: . ..::: . . ...:.:. . ...:. : :..: .: . . . .
NP_877 FFDRYPDSILEHQIQVRPFNALKTKNMRNLNPEDIDQLITISGMVIRTSQLIPEMQEAFF
250 260 270 280 290 300
180 190 200 210 220
pF1KB4 QCRSCRNTLTNIAMRPGLEGYALPRKCNTDQAGRPKC-PLDPYFIMPDKCKCVDFQTLKL
::. : .: : . : : : : : :: : . .. .. : : .::
NP_877 QCQVCAHT-TRVEMDRGR--IAEPSVC-----GR--CHTTHSMALIHNRSLFSDKQMIKL
310 320 330 340 350
230 240 250 260 270 280
pF1KB4 QELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTIMGIYSIKKFGL----TTSRGRDRV
:: :. .: :. :. . :. : ::: ::.::.. ::: . . .. .. ..
NP_877 QESPEDMPAGQTPHTVILFAHNDLVDKVQPGDRVNVTGIYRAVPIRVNPRVSNVKSVYKT
360 370 380 390 400 410
290 300 310 320 330 340
pF1KB4 GVGI----RSSYIRVLGIQVDTDGSGRSFAGAVSPQEEEEFRRLAALPNVYEVISKSIAP
. . ... :. :. : .. . : : .. : ...:. :..:: .....::
NP_877 HIDVIHYRKTDAKRLHGL--DEEAEQKLF----SEKRVELLKELSRKPDIYERLASALAP
420 430 440 450 460
350 360 370 380 390
pF1KB4 SIFGGTDMKKAIACLLFGGSRKRLPD-GLTR-RGDINLLMLGDPGTAKSQLLKFVEKCSP
::. :.::.: ::::.:: . : . :..::.:. :::::.:::::..: . :
NP_877 SIYEHEDIKKGILLQLFGGTRKDFSHTGRGKFRAEINILLCGDPGTSKSQLLQYVYNLVP
470 480 490 500 510 520
400 410 420 430 440 450
pF1KB4 IGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDDRVAIH
: :::::::::.:::: ::.:: .:..... ::.::.:.:. :::::::: :. : ..:
NP_877 RGQYTSGKGSSAVGLTAYVMKDPETRQLVLQTGALVLSDNGICCIDEFDKMNESTRSVLH
530 540 550 560 570 580
460 470 480 490 500 510
pF1KB4 EAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKGE-DNIDFMPTILSRFDMIF
:.:::::.::::::: ::.: ::::::: . ..:. : .::.. :.:::::.::
NP_877 EVMEQQTLSIAKAGIICQLNARTSVLAAANPIESQWNPKKTTIENIQLPHTLLSRFDLIF
590 600 610 620 630 640
520 530 540 550 560 570
pF1KB4 IVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPRLSAEA
.. : ..: : ::.:...:. . .. :: : .:.: :: .::: . :::: ::
NP_877 LLLDPQDEAYDRRLAHHLVALYYQ--SEEQAEEELLDMAVLKDYIAYAHSTIMPRLSEEA
650 660 670 680 690 700
580 590 600 610 620 630
pF1KB4 AEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFATEADVE
.. : . :. :: . .. :. . ::::...:.::: .:..:. . :::
NP_877 SQALIEAYVDMR-------KIGSSRGMVSAYPRQLESLIRLAEAHAKVRLSNKVEAIDVE
710 720 730 740 750
640 650 660 670 680
pF1KB4 EALRLFQVSTLDAA---------LSGTLSGVEGFTSQEDQEMLSRIEKQLKRRFAIGSQV
:: :: . . ..: .: .:. . ::.. .: :.. :.:
NP_877 EAKRLHREALKQSATDPRTGIVDISILTTGMSA-TSRKRKEELAEALKKLILSKGKTPAL
760 770 780 790 800 810
690 700 710 720 730
pF1KB4 SEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRKVLYRLK
NP_877 KYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTGKTVRLL
820 830 840 850 860
>>NP_001265524 (OMIM: 600592) DNA replication licensing (543 aa)
initn: 863 init1: 602 opt: 981 Z-score: 1102.8 bits: 214.2 E(85289): 1.1e-54
Smith-Waterman score: 992; 37.0% identity (65.9% similar) in 481 aa overlap (172-647:8-464)
150 160 170 180 190
pF1KB4 SDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYAL-P-RKCNT
: .: . . : . . : ..:.:
NP_001 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQT
10 20 30
200 210 220 230 240 250
pF1KB4 DQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVP
...: ... . . :: .:.:: : :: :..:: . . . . :
NP_001 NRSG------GRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQP
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB4 GNRVTIMGIY-SIKKFGLTTSRGRDRVGVGIRSSYIRVLGI-QVDTDGSGRSFAGAVSPQ
:..:.. ::. : . :. :. : . .:... : ... . . .: :: ..
NP_001 GDHVSVTGIFLPILRTGF-----RQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELT--
100 110 120 130 140
320 330 340 350 360 370
pF1KB4 EEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINL
.::.:..: . :: .. :::: :.: :.:::. :: :: . : :. ::.::.
NP_001 -REELRQIAE-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINI
150 160 170 180 190 200
380 390 400 410 420 430
pF1KB4 LMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLA
..::::.::::::..... .: . ::.:.:::..::::.:.:: : .. .::::.:::
NP_001 CLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLA
210 220 230 240 250 260
440 450 460 470 480 490
pF1KB4 DGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDE
: :: :::::::: : ::.::::.::::::::::::: ::::.:::.::::: ..::..
NP_001 DQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNP
270 280 290 300 310 320
500 510 520 530 540 550
pF1KB4 TKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDL
.. :.::.. ..:::::......:. ... :. ::.:. .: . . : .:.
NP_001 RRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFE-PLDM
330 340 350 360 370 380
560 570 580 590 600 610
pF1KB4 AKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAI
....::.:: : : . :. . :. :: : .:. :. : : ::
NP_001 KLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREA-WASKDATYTSA-----RTLLAI
390 400 410 420 430
620 630 640 650 660 670
pF1KB4 VRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIE
.:.. ::..... . . ::.::.::...:
NP_001 LRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELV
440 450 460 470 480 490
680 690 700 710 720 730
pF1KB4 KQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRKVLYRLK
NP_001 SGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV
500 510 520 530 540
>>NP_877577 (OMIM: 600592) DNA replication licensing fac (543 aa)
initn: 863 init1: 602 opt: 981 Z-score: 1102.8 bits: 214.2 E(85289): 1.1e-54
Smith-Waterman score: 992; 37.0% identity (65.9% similar) in 481 aa overlap (172-647:8-464)
150 160 170 180 190
pF1KB4 SDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYAL-P-RKCNT
: .: . . : . . : ..:.:
NP_877 MVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQT
10 20 30
200 210 220 230 240 250
pF1KB4 DQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVP
...: ... . . :: .:.:: : :: :..:: . . . . :
NP_877 NRSG------GRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQP
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB4 GNRVTIMGIY-SIKKFGLTTSRGRDRVGVGIRSSYIRVLGI-QVDTDGSGRSFAGAVSPQ
:..:.. ::. : . :. :. : . .:... : ... . . .: :: ..
NP_877 GDHVSVTGIFLPILRTGF-----RQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELT--
100 110 120 130 140
320 330 340 350 360 370
pF1KB4 EEEEFRRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINL
.::.:..: . :: .. :::: :.: :.:::. :: :: . : :. ::.::.
NP_877 -REELRQIAE-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINI
150 160 170 180 190 200
380 390 400 410 420 430
pF1KB4 LMLGDPGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLA
..::::.::::::..... .: . ::.:.:::..::::.:.:: : .. .::::.:::
NP_877 CLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLA
210 220 230 240 250 260
440 450 460 470 480 490
pF1KB4 DGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDE
: :: :::::::: : ::.::::.::::::::::::: ::::.:::.::::: ..::..
NP_877 DQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNP
270 280 290 300 310 320
500 510 520 530 540 550
pF1KB4 TKG-EDNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDL
.. :.::.. ..:::::......:. ... :. ::.:. .: . . : .:.
NP_877 RRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFE-PLDM
330 340 350 360 370 380
560 570 580 590 600 610
pF1KB4 AKLKKFIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAI
....::.:: : : . :. . :. :: : .:. :. : : ::
NP_877 KLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREA-WASKDATYTSA-----RTLLAI
390 400 410 420 430
620 630 640 650 660 670
pF1KB4 VRIAEALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIE
.:.. ::..... . . ::.::.::...:
NP_877 LRLSTALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELV
440 450 460 470 480 490
680 690 700 710 720 730
pF1KB4 KQLKRRFAIGSQVSEHSIIKDFTKQKYPEHAIHKVLQLMLRRGEIQHRMQRKVLYRLK
NP_877 SGGRSVRFSEAEQRCVSRGFTPAQFQAALDEYEELNVWQVNASRTRITFV
500 510 520 530 540
>>XP_005250405 (OMIM: 600592) PREDICTED: DNA replication (612 aa)
initn: 863 init1: 602 opt: 981 Z-score: 1102.1 bits: 214.3 E(85289): 1.2e-54
Smith-Waterman score: 1064; 35.6% identity (65.9% similar) in 536 aa overlap (119-647:22-533)
90 100 110 120 130 140
pF1KB4 YKQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDAS--PSSIRSLKSDMMS
:... ....... .: : :: ...: ..
XP_005 MMEQRSRDPGMVRSPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVG
10 20 30 40 50
150 160 170 180 190 200
pF1KB4 HLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYAL-P-RKCNTDQAGR
.:: . ::. .: :. : . . : .: . . : . . : ..:.:...:
XP_005 KLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSG-
60 70 80 90 100 110
210 220 230 240 250 260
pF1KB4 PKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVT
... . . :: .:.:: : :: :..:: . . . . ::..:.
XP_005 -----GRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVS
120 130 140 150 160
270 280 290 300 310 320
pF1KB4 IMGIY-SIKKFGLTTSRGRDRVGVGIRSSYIRVLGI-QVDTDGSGRSFAGAVSPQEEEEF
. ::. : . :. :. : . .:... : ... . . .: :: .. .::.
XP_005 VTGIFLPILRTGF-----RQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELT---REEL
170 180 190 200 210
330 340 350 360 370 380
pF1KB4 RRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGD
:..: . :: .. :::: :.: :.:::. :: :: . : :. ::.::. ..::
XP_005 RQIAE-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGD
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB4 PGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVV
::.::::::..... .: . ::.:.:::..::::.:.:: : .. .::::.:::: ::
XP_005 PGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVC
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB4 CIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-E
:::::::: : ::.::::.::::::::::::: ::::.:::.::::: ..::.. .. :
XP_005 CIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLE
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB4 DNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKK
.::.. ..:::::......:. ... :. ::.:. .: . . : .:. ...
XP_005 QNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFE-PLDMKLMRR
400 410 420 430 440 450
570 580 590 600 610 620
pF1KB4 FIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAE
.::.:: : : . :. . :. :: : .:. :. : : ::.:..
XP_005 YIAMCREK-QPMVPESLADYITAAYVEMRREA-WASKDATYTSA-----RTLLAILRLST
460 470 480 490 500
630 640 650 660 670 680
pF1KB4 ALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKR
::..... . . ::.::.::...:
XP_005 ALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRS
510 520 530 540 550 560
>>XP_016867706 (OMIM: 600592) PREDICTED: DNA replication (612 aa)
initn: 863 init1: 602 opt: 981 Z-score: 1102.1 bits: 214.3 E(85289): 1.2e-54
Smith-Waterman score: 1064; 35.6% identity (65.9% similar) in 536 aa overlap (119-647:22-533)
90 100 110 120 130 140
pF1KB4 YKQPAEHLQLLEEAAKEVADEVTRPRPSGEEVLQDIQVMLKSDAS--PSSIRSLKSDMMS
:... ....... .: : :: ...: ..
XP_016 MMEQRSRDPGMVRSPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVG
10 20 30 40 50
150 160 170 180 190 200
pF1KB4 HLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYAL-P-RKCNTDQAGR
.:: . ::. .: :. : . . : .: . . : . . : ..:.:...:
XP_016 KLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSG-
60 70 80 90 100 110
210 220 230 240 250 260
pF1KB4 PKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVT
... . . :: .:.:: : :: :..:: . . . . ::..:.
XP_016 -----GRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVS
120 130 140 150 160
270 280 290 300 310 320
pF1KB4 IMGIY-SIKKFGLTTSRGRDRVGVGIRSSYIRVLGI-QVDTDGSGRSFAGAVSPQEEEEF
. ::. : . :. :. : . .:... : ... . . .: :: .. .::.
XP_016 VTGIFLPILRTGF-----RQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELT---REEL
170 180 190 200 210
330 340 350 360 370 380
pF1KB4 RRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGD
:..: . :: .. :::: :.: :.:::. :: :: . : :. ::.::. ..::
XP_016 RQIAE-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGD
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB4 PGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVV
::.::::::..... .: . ::.:.:::..::::.:.:: : .. .::::.:::: ::
XP_016 PGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVC
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB4 CIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-E
:::::::: : ::.::::.::::::::::::: ::::.:::.::::: ..::.. .. :
XP_016 CIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLE
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB4 DNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKK
.::.. ..:::::......:. ... :. ::.:. .: . . : .:. ...
XP_016 QNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFE-PLDMKLMRR
400 410 420 430 440 450
570 580 590 600 610 620
pF1KB4 FIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAE
.::.:: : : . :. . :. :: : .:. :. : : ::.:..
XP_016 YIAMCREK-QPMVPESLADYITAAYVEMRREA-WASKDATYTSA-----RTLLAILRLST
460 470 480 490 500
630 640 650 660 670 680
pF1KB4 ALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKR
::..... . . ::.::.::...:
XP_016 ALARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRS
510 520 530 540 550 560
>>NP_005907 (OMIM: 600592) DNA replication licensing fac (719 aa)
initn: 863 init1: 602 opt: 981 Z-score: 1101.1 bits: 214.3 E(85289): 1.4e-54
Smith-Waterman score: 1091; 32.5% identity (62.0% similar) in 655 aa overlap (32-647:10-640)
10 20 30 40 50 60
pF1KB4 SGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELKR
... :.::... . ::: ..: :
NP_005 MALKDYALEKEKVKKFLQEFYQDDELGKKQFKYGNQLVR
10 20 30
70 80 90 100 110
pF1KB4 HYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKEVAD-----EVT-----
. . . :...:.: : .:.: . .. .. .:. .:..:. ::.
NP_005 LAHREQVALYVDLDDVAEDDPELVDSICENARRYAKLFADAVQELLPQYKEREVVNKDVL
40 50 60 70 80 90
120 130 140
pF1KB4 ------------RPRPSG----------EEVLQDIQVMLKSDAS--PSSIRSLKSDMMSH
: : : :... ....... .: : :: ...: ...
NP_005 DVYIEHRLMMEQRSRDPGMVRSPQNQYPAELMRRFELYFQGPSSNKPRVIREVRADSVGK
100 110 120 130 140 150
150 160 170 180 190 200
pF1KB4 LVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGYAL-P-RKCNTDQAGRP
:: . ::. .: :. : . . : .: . . : . . : ..:.:...:
NP_005 LVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSG--
160 170 180 190 200 210
210 220 230 240 250 260
pF1KB4 KCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCDRYLCDKVVPGNRVTI
... . . :: .:.:: : :: :..:: . . . . ::..:..
NP_005 ----GRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSV
220 230 240 250 260 270
270 280 290 300 310 320
pF1KB4 MGIY-SIKKFGLTTSRGRDRVGVGIRSSYIRVLGI-QVDTDGSGRSFAGAVSPQEEEEFR
::. : . :. :. : . .:... : ... . . .: :: .. .::.:
NP_005 TGIFLPILRTGF-----RQVVQGLLSETYLEAHRIVKMNKSEDDESGAGELT---REELR
280 290 300 310 320
330 340 350 360 370 380
pF1KB4 RLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDP
..: . :: .. :::: :.: :.:::. :: :: . : :. ::.::. ..:::
NP_005 QIAE-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDP
330 340 350 360 370 380
390 400 410 420 430 440
pF1KB4 GTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVC
:.::::::..... .: . ::.:.:::..::::.:.:: : .. .::::.:::: :: :
NP_005 GVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCC
390 400 410 420 430 440
450 460 470 480 490 500
pF1KB4 IDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-ED
::::::: : ::.::::.::::::::::::: ::::.:::.::::: ..::.. .. :.
NP_005 IDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQ
450 460 470 480 490 500
510 520 530 540 550 560
pF1KB4 NIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKF
::.. ..:::::......:. ... :. ::.:. .: . . : .:. ....
NP_005 NIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFE-PLDMKLMRRY
510 520 530 540 550 560
570 580 590 600 610 620
pF1KB4 IAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEA
::.:: : : . :. . :. :: : .:. :. : : ::.:.. :
NP_005 IAMCREK-QPMVPESLADYITAAYVEMRREA-WASKDATYTSA-----RTLLAILRLSTA
570 580 590 600 610
630 640 650 660 670 680
pF1KB4 LSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKRR
:..... . . ::.::.::...:
NP_005 LARLRMVDVVEKEDVNEAIRLMEMSKDSLLGDKGQTARTQRPADVIFATVRELVSGGRSV
620 630 640 650 660 670
>>NP_005906 (OMIM: 223100,601806) DNA replication licens (821 aa)
initn: 917 init1: 638 opt: 882 Z-score: 989.1 bits: 193.8 E(85289): 2.3e-48
Smith-Waterman score: 1011; 31.5% identity (62.3% similar) in 658 aa overlap (32-649:27-657)
10 20 30 40 50 60
pF1KB4 SGFDDPGIFYSDSFGGDAQADEGQARKSQLQRRFKEFLRQYRVGTDRTGFTFKYRDELKR
:. : .::.... . . . .. .:: :
NP_005 MDLAAAAEPGAGSQHLEVRDEVAEKCQKLFLDFLEEFQSSDGEIKY-LQLAEELIR
10 20 30 40 50
70 80 90 100 110
pF1KB4 -HYNLGEYWIEVEMEDLASFDEDLADYLYKQPAEHLQLLEEAAKE-VADEVTRPRPSGEE
. : . : . :: .:...:. . .. . : .: : : :. :
NP_005 PERNT----LVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKDRKEIP------
60 70 80 90 100
120 130 140 150 160 170
pF1KB4 VLQDIQVMLKSDASPSSIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTL
. .:. : ... . .:: : :. .. :..: : .. . :. . . .. : .:....
NP_005 LAKDFYVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVI
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB4 TNIAMRPGLEGYALPRKCNTDQAGRPKCPLDPYFIMP-DKCKCVDFQTLKLQELPDAVPH
.. .. :. : : . : : :.. .: . :::: ...:: .:.
NP_005 RDVEQQ---FKYTQPNICRN-----PVCANRRRFLLDTNKSRFVDFQKVRIQETQAELPR
170 180 190 200 210
240 250 260 270 280
pF1KB4 GEMPRHMQLYCDRYLCDKVVPGNRVTIMG----IYSIKKFGL------TTSR-----GRD
: .:: ... ... :.. . : . ...:.. :.:: : .
NP_005 GSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDGYE
220 230 240 250 260 270
290 300 310 320
pF1KB4 RVGV-GIRSSYIRVLGIQV--------------------DTDGSGRSFAGAVSPQEEEEF
:. :.:. .: :. .. : . ...:. . .. .: :.
NP_005 TEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWEKV
280 290 300 310 320 330
330 340 350 360 370 380
pF1KB4 RRLAALPNVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGD
... :.:. . :. :.: :. ..:... .:::: : .: . :::::. ..::
NP_005 FEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIVGD
340 350 360 370 380 390
390 400 410 420 430 440
pF1KB4 PGTAKSQLLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVV
:.:::::.:: ::. :: .::::::.::::::::.:.:: :..:..:.::..:::.::
NP_005 PSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNGVC
400 410 420 430 440 450
450 460 470 480 490 500
pF1KB4 CIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-E
:::::::: :.::::::::::::::.:::. .:::.: :.::::: . :..:..:. .
NP_005 CIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKSLK
460 470 480 490 500 510
510 520 530 540 550 560
pF1KB4 DNIDFMPTILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKK
.::.. :.::::..::. :: :: : .:.... :: : . .. .. .: ...
NP_005 QNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLH-SRIEES--IDRVYSLDDIRR
520 530 540 550 560 570
570 580 590 600 610 620
pF1KB4 FIAYCRVKCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAE
.. . : . :..: :. . . ..: .: :.. .. .:: :::::::...:..:
NP_005 YLLFAR-QFKPKISKESEDFIVEQYKHLR----QRDGSGVTKSSWRITVRQLESMIRLSE
580 590 600 610 620
630 640 650 660 670 680
pF1KB4 ALSKMKLQPFATEADVEEALRLFQVSTLDAALSGTLSGVEGFTSQEDQEMLSRIEKQLKR
:...:. . :.::.::.. : .
NP_005 AMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEEEIQMEVDEGAGGINGHADS
630 640 650 660 670 680
734 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:14:49 2016 done: Fri Nov 4 03:14:51 2016
Total Scan time: 10.600 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]