Result of FASTA (omim) for
pF1KB4735
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4735, 384 aa
1>>>pF1KB4735 384 - 384 aa - 384 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3644+/-0.000376; mu= 15.8942+/- 0.023
mean_var=66.4509+/-13.243, 0's: 0 Z-trim(113.3): 37 B-trim: 201 in 1/50
Lambda= 0.157334
statistics sampled from 22504 (22541) to 22504 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.65), E-opt: 0.2 (0.264), width: 16
Scan time: 6.040
The best scores are: opt bits E(85289)
NP_068594 (OMIM: 607113) DNA dC->dU-editing enzyme ( 384) 2801 644.9 9.5e-185
XP_016884392 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 524) 2774 638.8 8.7e-183
XP_006724353 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 317) 2327 537.2 2e-152
XP_016884393 (OMIM: 607113) PREDICTED: DNA dC->dU- ( 457) 2300 531.2 1.9e-150
NP_004891 (OMIM: 607110) DNA dC->dU-editing enzyme ( 382) 1473 343.4 5.2e-94
NP_660341 (OMIM: 608993) DNA dC->dU-editing enzyme ( 373) 1258 294.6 2.5e-79
XP_016884131 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 227) 827 196.7 4.7e-50
NP_663745 (OMIM: 607109) DNA dC->dU-editing enzyme ( 199) 820 195.0 1.3e-49
NP_001257335 (OMIM: 607109) DNA dC->dU-editing enz ( 181) 759 181.2 1.7e-45
XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 442) 689 165.5 2.2e-40
NP_001257340 (OMIM: 607110) DNA dC->dU-editing enz ( 357) 524 128.0 3.5e-29
NP_055323 (OMIM: 607750) DNA dC->dU-editing enzyme ( 190) 513 125.4 1.1e-28
NP_689639 (OMIM: 609900) DNA dC->dU-editing enzyme ( 386) 511 125.1 2.9e-28
XP_016884085 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 455) 511 125.1 3.3e-28
XP_005261394 (OMIM: 609900) PREDICTED: DNA dC->dU- ( 202) 435 107.7 2.6e-23
NP_065712 (OMIM: 605257,605258) single-stranded DN ( 198) 402 100.2 4.6e-21
XP_016884132 (OMIM: 608993) PREDICTED: DNA dC->dU- ( 101) 397 98.9 5.7e-21
NP_001006667 (OMIM: 608993) DNA dC->dU-editing enz ( 101) 397 98.9 5.7e-21
NP_861438 (OMIM: 610976) DNA dC->dU-editing enzyme ( 183) 349 88.1 1.8e-17
NP_001159474 (OMIM: 610976) DNA dC->dU-editing enz ( 182) 344 87.0 3.9e-17
XP_011528294 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 200) 344 87.0 4.2e-17
NP_001159475 (OMIM: 610976) DNA dC->dU-editing enz ( 200) 344 87.0 4.2e-17
XP_011528292 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203) 344 87.0 4.3e-17
XP_011528293 (OMIM: 610976) PREDICTED: DNA dC->dU- ( 203) 344 87.0 4.3e-17
NP_001317272 (OMIM: 605257,605258) single-stranded ( 188) 330 83.8 3.6e-16
NP_001291495 (OMIM: 600130) C->U-editing enzyme AP ( 236) 307 78.6 1.6e-14
NP_001635 (OMIM: 600130) C->U-editing enzyme APOBE ( 236) 307 78.6 1.6e-14
NP_005880 (OMIM: 600130) C->U-editing enzyme APOBE ( 191) 294 75.6 1.1e-13
NP_006780 (OMIM: 604797) C->U-editing enzyme APOBE ( 224) 294 75.7 1.2e-13
XP_011519075 (OMIM: 605257,605258) PREDICTED: sing ( 145) 281 72.6 6.5e-13
NP_001159476 (OMIM: 610976) DNA dC->dU-editing enz ( 154) 250 65.6 9e-11
>>NP_068594 (OMIM: 607113) DNA dC->dU-editing enzyme APO (384 aa)
initn: 2801 init1: 2801 opt: 2801 Z-score: 3437.8 bits: 644.9 E(85289): 9.5e-185
Smith-Waterman score: 2801; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:1-384)
10 20 30 40 50 60
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_068 KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
310 320 330 340 350 360
370 380
pF1KB4 WDGLDEHSQDLSGRLRAILQNQEN
::::::::::::::::::::::::
NP_068 WDGLDEHSQDLSGRLRAILQNQEN
370 380
>>XP_016884392 (OMIM: 607113) PREDICTED: DNA dC->dU-edit (524 aa)
initn: 2774 init1: 2774 opt: 2774 Z-score: 3402.6 bits: 638.8 E(85289): 8.7e-183
Smith-Waterman score: 2774; 100.0% identity (100.0% similar) in 380 aa overlap (1-380:1-380)
10 20 30 40 50 60
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
310 320 330 340 350 360
370 380
pF1KB4 WDGLDEHSQDLSGRLRAILQNQEN
::::::::::::::::::::
XP_016 WDGLDEHSQDLSGRLRAILQVRASSLCPVPHRPPPPPLSPAPCLPLCSEPPLGSLLPQGT
370 380 390 400 410 420
>>XP_006724353 (OMIM: 607113) PREDICTED: DNA dC->dU-edit (317 aa)
initn: 2327 init1: 2327 opt: 2327 Z-score: 2857.6 bits: 537.2 E(85289): 2e-152
Smith-Waterman score: 2327; 100.0% identity (100.0% similar) in 317 aa overlap (68-384:1-317)
40 50 60 70 80 90
pF1KB4 EVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPC
::::::::::::::::::::::::::::::
XP_006 MRFFHWFSKWRKLHRDQEYEVTWYISWSPC
10 20 30
100 110 120 130 140 150
pF1KB4 TKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEF
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB4 QHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHE
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB4 TYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDY
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB4 RVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISI
220 230 240 250 260 270
340 350 360 370 380
pF1KB4 MTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
:::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
280 290 300 310
>>XP_016884393 (OMIM: 607113) PREDICTED: DNA dC->dU-edit (457 aa)
initn: 2300 init1: 2300 opt: 2300 Z-score: 2822.1 bits: 531.2 E(85289): 1.9e-150
Smith-Waterman score: 2300; 100.0% identity (100.0% similar) in 313 aa overlap (68-380:1-313)
40 50 60 70 80 90
pF1KB4 EVKTKGPSRPPLDAKIFRGQVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPC
::::::::::::::::::::::::::::::
XP_016 MRFFHWFSKWRKLHRDQEYEVTWYISWSPC
10 20 30
100 110 120 130 140 150
pF1KB4 TKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TKCTRDMATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEF
40 50 60 70 80 90
160 170 180 190 200 210
pF1KB4 QHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHE
100 110 120 130 140 150
220 230 240 250 260 270
pF1KB4 TYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TYLCYEVERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDY
160 170 180 190 200 210
280 290 300 310 320 330
pF1KB4 RVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISI
220 230 240 250 260 270
340 350 360 370 380
pF1KB4 MTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
:::::::::::::::::::::::::::::::::::::::::::
XP_016 MTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQVRASSLCPVPHRPPPPP
280 290 300 310 320 330
XP_016 LSPAPCLPLCSEPPLGSLLPQGTCLCPSLSFSQPPFLSHLPHPSLLSDHCHCPQASTICL
340 350 360 370 380 390
>>NP_004891 (OMIM: 607110) DNA dC->dU-editing enzyme APO (382 aa)
initn: 1343 init1: 579 opt: 1473 Z-score: 1808.7 bits: 343.4 E(85289): 5.2e-94
Smith-Waterman score: 1473; 56.6% identity (75.2% similar) in 387 aa overlap (1-384:1-382)
10 20 30 40 50
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPPLDAKIFRGQVY
:.:..:: .:::::::: :: :.::: :. .::::::: : : : :. .::::::
NP_004 MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGQVY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 SELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIF
. .:: :: :. :: .: . ...::..::.:: :. .: ::.: :.:::::
NP_004 FKPQYHAEMCFLSWFCG-NQLPAYKCFQITWFVSWTPCPDCVAKLAEFLSEHPNVTLTIS
70 80 90 100 110
120 130 140 150 160 170
pF1KB4 VARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLP
.:::::.:. ::..:: : : : : .:::.:.:: .:: .:::.. . : :: ..
NP_004 AARLYYYWERDYRRALCRLSQA--GAR--VKIMDYEEFAYCWENFVYNEGQQFMPWYKFD
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB4 KYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRR
. : .:: : ::::. ::: ::::::::.: : :..:::::::::. : ::::..:.
NP_004 ENYAFLHRTLKEILRYLMDPDTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHM
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 GFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFS--CAQEMAK
:::::.: . . :::::: :::..: .:: : :::: : ::::::: :: :.
NP_004 GFLCNEAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 FISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCP
:...: :: : ::.::::: . .:.:. : .:::..:::::.::..:::::: .::::
NP_004 FLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCP
300 310 320 330 340 350
360 370 380
pF1KB4 FQPWDGLDEHSQDLSGRLRAILQNQEN
:::::::.:::: :::::::::::: :
NP_004 FQPWDGLEEHSQALSGRLRAILQNQGN
360 370 380
>>NP_660341 (OMIM: 608993) DNA dC->dU-editing enzyme APO (373 aa)
initn: 1306 init1: 460 opt: 1258 Z-score: 1545.1 bits: 294.6 E(85289): 2.5e-79
Smith-Waterman score: 1258; 50.8% identity (72.8% similar) in 386 aa overlap (1-380:1-373)
10 20 30 40 50 60
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_660 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
. ..: :: :. :: .: . ...::..::.:: :. .: :::: :.::::: .
NP_660 QPEHHAEMCFLSWFCG-NQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
70 80 90 100 110
130 140 150 160 170 180
pF1KB4 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
:::::.:. ::..:: : : : : .:::. .:: .:: .::::. . : :: ..
NP_660 ARLYYYWERDYRRALCRLSQA--GAR--VKIMDDEEFAYCWENFVYSEGQPFMPWYKFDD
120 130 140 150 160 170
190 200 210 220 230
pF1KB4 YYILLHIMLGEILRHSMD---PPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQ
: .:: : ::::. :. : : :.:.: . ::.:..::. .: ... . : .
NP_660 NYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSPV--SW
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 RRGFLCNQA-PHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMA
.:: . ::. :. : ::: :::. . :. . .:.:: .:::::: :: :.:
NP_660 KRGVFRNQVDPETHC-----HAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVA
240 250 260 270 280
300 310 320 330 340 350
pF1KB4 KFISKNKHVSLCIFTARIYD--DQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQ
.:......:.: :::::.: : :::::.:.. ::.. :: :..::.::..:: ..
NP_660 EFLARHSNVNLTIFTARLYYFWDTDY-QEGLRSLSQEGASVEIMGYKDFKYCWENFVYND
290 300 310 320 330 340
360 370 380
pF1KB4 GCPFQPWDGLDEHSQDLSGRLRAILQNQEN
::.:: :: . :...:. ::.
NP_660 DEPFKPWKGLKYNFLFLDSKLQEILE
350 360 370
>>XP_016884131 (OMIM: 608993) PREDICTED: DNA dC->dU-edit (227 aa)
initn: 822 init1: 460 opt: 827 Z-score: 1019.7 bits: 196.7 E(85289): 4.7e-50
Smith-Waterman score: 827; 54.4% identity (70.5% similar) in 237 aa overlap (1-226:1-224)
10 20 30 40 50 60
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_016 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
. ..: :: :. :: .: . ...::..::.:: :. .: :::: :.::::: .
XP_016 QPEHHAEMCFLSWFCG-NQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
70 80 90 100 110
130 140 150 160 170 180
pF1KB4 ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
:::::.:. ::..:: : : : : .:::. .:: .:: .::::. . : :: ..
XP_016 ARLYYYWERDYRRALCRLSQA--GAR--VKIMDDEEFAYCWENFVYSEGQPFMPWYKFDD
120 130 140 150 160 170
190 200 210 220
pF1KB4 YYILLHIMLGEILR-----------HSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHN
: .:: : :::: ::. ::. . :: :. .:... :
XP_016 NYAFLHRTLKEILRATSIHLRGRPPHSLGSPTWLL---PSPW----HNR-ICHKTGRKWA
180 190 200 210 220
230 240 250 260 270 280
pF1KB4 DTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCF
>>NP_663745 (OMIM: 607109) DNA dC->dU-editing enzyme APO (199 aa)
initn: 828 init1: 471 opt: 820 Z-score: 1012.0 bits: 195.0 E(85289): 1.3e-49
Smith-Waterman score: 820; 65.3% identity (77.2% similar) in 193 aa overlap (194-384:10-199)
170 180 190 200 210 220
pF1KB4 FVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYE
:: ::: :: :::: :::.::::::
NP_663 MEASPASGPRHLMDPHIFTSNFNNGI---GRHKTYLCYE
10 20 30
230 240 250 260 270 280
pF1KB4 VERMHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFT
:::. : : : ..:.:::: ::: . . :::::: :::..: .:: : :::: :
NP_663 VERLDNGTSVKMDQHRGFLHNQAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFI
40 50 60 70 80 90
290 300 310 320 330 340
pF1KB4 SWSPCFS--CAQEMAKFISKNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYS
::::::: :: :. :...: :: : ::.::::: . .:.:. : .:::..:::::.
NP_663 SWSPCFSWGCAGEVRAFLQENTHVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYD
100 110 120 130 140 150
350 360 370 380
pF1KB4 EFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
:::::::::::::::::::::::::::: :::::::::::: :
NP_663 EFKHCWDTFVDHQGCPFQPWDGLDEHSQALSGRLRAILQNQGN
160 170 180 190
>>NP_001257335 (OMIM: 607109) DNA dC->dU-editing enzyme (181 aa)
initn: 759 init1: 471 opt: 759 Z-score: 937.8 bits: 181.2 E(85289): 1.7e-45
Smith-Waterman score: 759; 66.3% identity (79.7% similar) in 172 aa overlap (215-384:10-181)
190 200 210 220 230 240
pF1KB4 LHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRGFLCN
::.:::::::::. : : : ..:.:::: :
NP_001 MEASPASGPRHKTYLCYEVERLDNGTSVKMDQHRGFLHN
10 20 30
250 260 270 280 290 300
pF1KB4 QAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFS--CAQEMAKFISKN
:: . . :::::: :::..: .:: : :::: : ::::::: :: :. :...:
NP_001 QAKNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQEN
40 50 60 70 80 90
310 320 330 340 350 360
pF1KB4 KHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWD
:: : ::.::::: . .:.:. : .:::..:::::.:::::::::::::::::::::
NP_001 THVRLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWD
100 110 120 130 140 150
370 380
pF1KB4 GLDEHSQDLSGRLRAILQNQEN
::::::: :::::::::::: :
NP_001 GLDEHSQALSGRLRAILQNQGN
160 170 180
>>XP_011528296 (OMIM: 608993) PREDICTED: DNA dC->dU-edit (442 aa)
initn: 1306 init1: 460 opt: 689 Z-score: 846.0 bits: 165.5 E(85289): 2.2e-40
Smith-Waterman score: 1056; 44.3% identity (62.6% similar) in 422 aa overlap (1-351:1-413)
10 20 30 40 50 60
pF1KB4 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_011 MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPRLDAKIFRGQVYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
. ..: :: :. :: .: . ...::..::.:: :. .: :::: :.::::: .
XP_011 QPEHHAEMCFLSWFCG-NQLPAYKCFQITWFVSWTPCPDCVAKLAEFLAEHPNVTLTISA
70 80 90 100 110
130 140 150
pF1KB4 ARLYYFWDPDYQEALRSLCQ---------------KRDGP---RATMK---IMN------
:::::.:. ::..:: : : . .: : .:: : :
XP_011 ARLYYYWERDYRRALCRLSQAGARVKIMDDEGERWRGQGSVSGRNSMKDGWICNAMAGGV
120 130 140 150 160 170
160 170
pF1KB4 --------------------------------------YDEFQHCWSKFVYSQRELFEPW
.:: .:: .::::. . : ::
XP_011 PGQPAGAGPALTATDSQETRPGSAGPGSGQSLTASCLFVSEFAYCWENFVYSEGQPFMPW
180 190 200 210 220 230
180 190 200 210 220 230
pF1KB4 NNLPKYYILLHIMLGEILRHSMD---PPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTW
.. : .:: : ::::. :. : : :.:.: . ::.:..::. .: ... .
XP_011 YKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKHHSP
240 250 260 270 280 290
240 250 260 270 280 290
pF1KB4 VLLNQRRGFLCNQA-PHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSC
: . .:: . ::. :. : ::: :::. . :. . .:.:: .:::::: :
XP_011 V--SWKRGVFRNQVDPETHC-----HAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPEC
300 310 320 330 340 350
300 310 320 330 340
pF1KB4 AQEMAKFISKNKHVSLCIFTARIYD--DQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDT
: :.:.:......:.: :::::.: : :::::.:.. ::.. :: :..::.::..
XP_011 AGEVAEFLARHSNVNLTIFTARLYYFWDTDY-QEGLRSLSQEGASVEIMGYKDFKYCWEN
360 370 380 390 400 410
350 360 370 380
pF1KB4 FVDHQGCPFQPWDGLDEHSQDLSGRLRAILQNQEN
::
XP_011 FVYNDDEPFKPWKGLKYNFLFLDSKLQEILE
420 430 440
384 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:12:07 2016 done: Fri Nov 4 03:12:08 2016
Total Scan time: 6.040 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]