FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB4674, 392 aa
  1>>>pF1KB4674 392 - 392 aa - 392 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7742+/-0.000883; mu= 14.0336+/- 0.053
 mean_var=68.0383+/-13.529, 0's: 0 Z-trim(106.1): 11  B-trim: 7 in 1/49
 Lambda= 0.155488
 statistics sampled from 8813 (8818) to 8813 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.271), width:  16
 Scan time:  2.550

The best scores are:                                      opt bits E(32554)
CCDS4994.1 BCKDHB gene_id:594|Hs108|chr6           ( 392) 2677 609.6 1.6e-174
CCDS82795.1 PDHB gene_id:5162|Hs108|chr3           ( 341)  630 150.4 2.4e-36
CCDS2890.1 PDHB gene_id:5162|Hs108|chr3            ( 359)  630 150.4 2.5e-36


>>CCDS4994.1 BCKDHB gene_id:594|Hs108|chr6                (392 aa)
 initn: 2677 init1: 2677 opt: 2677  Z-score: 3246.8  bits: 609.6 E(32554): 1.6e-174
Smith-Waterman score: 2677; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392)

               10        20        30        40        50        60
pF1KB4 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 MAVVAAAAGWLLRLRAAGAEGHWRRLPGAGLARGFLHPAATVEDAAQRRQVAHFTFQPDP
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB4 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 EPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVAFGGVFRCTVGLRDKYGKDRVF
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB4 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 NTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFNCGSL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB4 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 TIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNPCIFFEP
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB4 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 KILYRAAAEEVPIEPYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVSCE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB4 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS49 VIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLTGGFASEISSTVQEECFLNLEAPISRV
              310       320       330       340       350       360

              370       380       390  
pF1KB4 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
       ::::::::::::::::::::::::::::::::
CCDS49 CGYDTPFPHIFEPFYIPDKWKCYDALRKMINY
              370       380       390  

>>CCDS82795.1 PDHB gene_id:5162|Hs108|chr3                (341 aa)
 initn: 464 init1: 178 opt: 630  Z-score: 766.1  bits: 150.4 E(32554): 2.4e-36
Smith-Waterman score: 630; 34.4% identity (67.1% similar) in 331 aa overlap (69-391:13-340)

       40        50        60        70        80        90        
pF1KB4 AATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDV
                                     ..... .......:. : .:  . ..::.:
CCDS82                   MAAVSGLVRRPLREVTVRDAINQGMDEELERDEKVFLLGEEV
                                 10        20        30        40  

       100       110       120       130       140       150       
pF1KB4 A-FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAF
       : . :... . ::  :::  :...::. :.:..:...: :..:   : :..  .. . :.
CCDS82 AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
             50        60        70        80        90       100  

       160       170       180       190       200       210       
pF1KB4 DQIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRS
       ::..: :::  : :: :     ...:.: :  .  :  :::   :...::::.::: : .
CCDS82 DQVINSAAKTYYMSGGLQPV-PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWN
            110       120        130       140       150       160 

       220       230       240          250       260       270    
pF1KB4 PFQAKGLLLSCIEDKNPCIFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTL
         .::::. : :.:.:: . .: ...: .  :   :.  . . ::...:.. ..:. .:.
CCDS82 SEDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITV
             170       180       190       200       210       220 

          280        290       300       310       320       330   
pF1KB4 VAWGTQV-HVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPL
       :. .  : : .. .: ..::  :: ::::..::: : :..::  ::.::..:.  . .  
CCDS82 VSHSRPVGHCLEAAAVLSKE--GVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWP
             230       240         250       260       270         

           340       350        360         370       380       390
pF1KB4 TGGFASEISSTVQEECFLN-LEAPISRVCGYDTPFPH--IFEPFYIPDKWKCYDALRKMI
         : ..:: . ..:   .: :.::  :: : :.:.:.  :.:   ::.      :..: .
CCDS82 QFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTL
     280       290       300       310       320       330         

         
pF1KB4 NY
       : 
CCDS82 NI
     340 

>>CCDS2890.1 PDHB gene_id:5162|Hs108|chr3                 (359 aa)
 initn: 464 init1: 178 opt: 630  Z-score: 765.8  bits: 150.4 E(32554): 2.5e-36
Smith-Waterman score: 630; 34.5% identity (67.0% similar) in 330 aa overlap (70-391:32-358)

      40        50        60        70        80        90         
pF1KB4 ATVEDAAQRRQVAHFTFQPDPEPREYGQTQKMNLFQSVTSALDNSLAKDPTAVIFGEDVA
                                     .... .......:. : .:  . ..::.::
CCDS28 AAVSGLVRRPLREVSGLLKRRFHWTAPAALQVTVRDAINQGMDEELERDEKVFLLGEEVA
              10        20        30        40        50        60 

      100       110       120       130       140       150        
pF1KB4 -FGGVFRCTVGLRDKYGKDRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFD
        . :... . ::  :::  :...::. :.:..:...: :..:   : :..  .. . :.:
CCDS28 QYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAID
              70        80        90       100       110       120 

      160       170       180       190       200       210        
pF1KB4 QIVNEAAKYRYRSGDLFNCGSLTIRSPWGCVGHGALYHSQSPEAFFAHCPGIKVVIPRSP
       :..: :::  : :: :     ...:.: :  .  :  :::   :...::::.::: : . 
CCDS28 QVINSAAKTYYMSGGLQPV-PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
             130       140        150       160       170       180

      220       230       240          250       260       270     
pF1KB4 FQAKGLLLSCIEDKNPCIFFEPKILYRAAAE---EVPIEPYNIPLSQAEVIQEGSDVTLV
        .::::. : :.:.:: . .: ...: .  :   :.  . . ::...:.. ..:. .:.:
CCDS28 EDAKGLIKSAIRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVV
              190       200       210       220       230       240

         280        290       300       310       320       330    
pF1KB4 AWGTQV-HVIREVASMAKEKLGVSCEVIDLRTIIPWDVDTICKSVIKTGRLLISHEAPLT
       . .  : : .. .: ..::  :: ::::..::: : :..::  ::.::..:.  . .   
CCDS28 SHSRPVGHCLEAAAVLSKE--GVECEVINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQ
              250         260       270       280       290        

          340       350        360         370       380       390 
pF1KB4 GGFASEISSTVQEECFLN-LEAPISRVCGYDTPFPH--IFEPFYIPDKWKCYDALRKMIN
        : ..:: . ..:   .: :.::  :: : :.:.:.  :.:   ::.      :..: .:
CCDS28 FGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKDIIFAIKKTLN
      300       310       320       330       340       350        

        
pF1KB4 Y
        
CCDS28 I
        




392 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Sat Nov  5 05:59:15 2016 done: Sat Nov  5 05:59:15 2016
 Total Scan time:  2.550 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]