Result of FASTA (omim) for
pF1KB4636
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4636, 1126 aa
1>>>pF1KB4636 1126 - 1126 aa - 1126 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 14.4287+/-0.000458; mu= -17.7445+/- 0.029
mean_var=667.1551+/-137.771, 0's: 0 Z-trim(124.8): 68 B-trim: 0 in 0/61
Lambda= 0.049655
statistics sampled from 47223 (47318) to 47223 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.794), E-opt: 0.2 (0.555), width: 16
Scan time: 20.560
The best scores are: opt bits E(85289)
NP_542434 (OMIM: 142590) large proline-rich protei (1126) 7643 563.5 2.6e-159
NP_542433 (OMIM: 142590) large proline-rich protei (1126) 7643 563.5 2.6e-159
NP_001092004 (OMIM: 142590) large proline-rich pro (1126) 7643 563.5 2.6e-159
XP_016866781 (OMIM: 142590) PREDICTED: large proli (1125) 7624 562.1 6.6e-159
NP_004630 (OMIM: 142590) large proline-rich protei (1132) 7621 561.9 7.7e-159
NP_001186627 (OMIM: 142590) large proline-rich pro (1077) 7118 525.9 5.2e-148
XP_016866785 (OMIM: 142590) PREDICTED: large proli (1076) 7099 524.5 1.3e-147
XP_016866782 (OMIM: 142590) PREDICTED: large proli (1108) 6619 490.1 3.1e-137
XP_016866787 (OMIM: 142590) PREDICTED: large proli (1028) 6514 482.6 5.3e-135
XP_016866778 (OMIM: 142590) PREDICTED: large proli (1135) 4783 358.6 1.2e-97
XP_011513194 (OMIM: 142590) PREDICTED: large proli (1173) 4428 333.2 5.6e-90
XP_016866776 (OMIM: 142590) PREDICTED: large proli (1162) 4416 332.3 1e-89
XP_016866783 (OMIM: 142590) PREDICTED: large proli (1100) 4415 332.2 1e-89
XP_016866775 (OMIM: 142590) PREDICTED: large proli (1164) 4409 331.8 1.4e-89
XP_016866774 (OMIM: 142590) PREDICTED: large proli (1164) 4409 331.8 1.4e-89
XP_016866764 (OMIM: 142590) PREDICTED: large proli (1182) 4409 331.8 1.5e-89
XP_016866771 (OMIM: 142590) PREDICTED: large proli (1182) 4409 331.8 1.5e-89
XP_016866767 (OMIM: 142590) PREDICTED: large proli (1182) 4409 331.8 1.5e-89
XP_016866769 (OMIM: 142590) PREDICTED: large proli (1182) 4409 331.8 1.5e-89
XP_016866766 (OMIM: 142590) PREDICTED: large proli (1182) 4409 331.8 1.5e-89
XP_016866768 (OMIM: 142590) PREDICTED: large proli (1182) 4409 331.8 1.5e-89
XP_016866770 (OMIM: 142590) PREDICTED: large proli (1182) 4409 331.8 1.5e-89
XP_016866765 (OMIM: 142590) PREDICTED: large proli (1182) 4409 331.8 1.5e-89
XP_016866777 (OMIM: 142590) PREDICTED: large proli (1143) 4391 330.5 3.5e-89
XP_016866773 (OMIM: 142590) PREDICTED: large proli (1171) 4390 330.5 3.7e-89
XP_016866772 (OMIM: 142590) PREDICTED: large proli (1181) 4390 330.5 3.7e-89
XP_016866780 (OMIM: 142590) PREDICTED: large proli (1133) 3884 294.2 3e-78
XP_016866786 (OMIM: 142590) PREDICTED: large proli (1094) 3866 292.9 7.1e-78
NP_001186626 (OMIM: 142590) large proline-rich pro ( 903) 3745 284.2 2.5e-75
XP_016866784 (OMIM: 142590) PREDICTED: large proli (1085) 3299 252.3 1.2e-65
XP_016866779 (OMIM: 142590) PREDICTED: large proli (1134) 3299 252.3 1.2e-65
>>NP_542434 (OMIM: 142590) large proline-rich protein BA (1126 aa)
initn: 7643 init1: 7643 opt: 7643 Z-score: 2981.3 bits: 563.5 E(85289): 2.6e-159
Smith-Waterman score: 7643; 100.0% identity (100.0% similar) in 1126 aa overlap (1-1126:1-1126)
10 20 30 40 50 60
pF1KB4 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120
pF1KB4 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
::::::::::::::::::::::::::::::::::::::::::::::
NP_542 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
1090 1100 1110 1120
>>NP_542433 (OMIM: 142590) large proline-rich protein BA (1126 aa)
initn: 7643 init1: 7643 opt: 7643 Z-score: 2981.3 bits: 563.5 E(85289): 2.6e-159
Smith-Waterman score: 7643; 100.0% identity (100.0% similar) in 1126 aa overlap (1-1126:1-1126)
10 20 30 40 50 60
pF1KB4 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_542 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120
pF1KB4 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
::::::::::::::::::::::::::::::::::::::::::::::
NP_542 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
1090 1100 1110 1120
>>NP_001092004 (OMIM: 142590) large proline-rich protein (1126 aa)
initn: 7643 init1: 7643 opt: 7643 Z-score: 2981.3 bits: 563.5 E(85289): 2.6e-159
Smith-Waterman score: 7643; 100.0% identity (100.0% similar) in 1126 aa overlap (1-1126:1-1126)
10 20 30 40 50 60
pF1KB4 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120
pF1KB4 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
1090 1100 1110 1120
>>XP_016866781 (OMIM: 142590) PREDICTED: large proline-r (1125 aa)
initn: 4105 init1: 4105 opt: 7624 Z-score: 2973.9 bits: 562.1 E(85289): 6.6e-159
Smith-Waterman score: 7624; 99.9% identity (99.9% similar) in 1126 aa overlap (1-1126:1-1125)
10 20 30 40 50 60
pF1KB4 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_016 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTL-GAGLGTNASLAQMVSGLVG
490 500 510 520 530
550 560 570 580 590 600
pF1KB4 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB4 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB4 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB4 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB4 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB4 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB4 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB4 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB4 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120
pF1KB4 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
1080 1090 1100 1110 1120
>>NP_004630 (OMIM: 142590) large proline-rich protein BA (1132 aa)
initn: 6457 init1: 6457 opt: 7621 Z-score: 2972.7 bits: 561.9 E(85289): 7.7e-159
Smith-Waterman score: 7621; 99.5% identity (99.5% similar) in 1132 aa overlap (1-1126:1-1132)
10 20 30 40 50 60
pF1KB4 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
130 140 150 160 170 180
190 200 210 220 230
pF1KB4 SRME------CRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVE
:::: ::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SRMETLPYLQCRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB4 ERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ERAPAQNPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB4 LGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LGAAATTDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB4 MSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSHYTTPMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB4 ESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ESSAEGAPPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB4 PPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQM
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB4 VSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQP
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB4 SMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPP
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB4 PPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB4 GSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQR
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB4 LQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB4 FLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIR
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB4 RMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGA
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB4 ERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVP
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB4 IIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 IIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLT
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120
pF1KB4 SPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 SPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
1090 1100 1110 1120 1130
>>NP_001186627 (OMIM: 142590) large proline-rich protein (1077 aa)
initn: 7118 init1: 7118 opt: 7118 Z-score: 2778.2 bits: 525.9 E(85289): 5.2e-148
Smith-Waterman score: 7228; 95.6% identity (95.6% similar) in 1126 aa overlap (1-1126:1-1077)
10 20 30 40 50 60
pF1KB4 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
::::::::::::::::::::::::::
NP_001 QSQRKVKPQPPLSDAYLSGMPAKRRK----------------------------------
1030 1040
1090 1100 1110 1120
pF1KB4 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
:::::::::::::::::::::::::::::::
NP_001 ---------------LRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
1050 1060 1070
>>XP_016866785 (OMIM: 142590) PREDICTED: large proline-r (1076 aa)
initn: 3832 init1: 3618 opt: 7099 Z-score: 2770.9 bits: 524.5 E(85289): 1.3e-147
Smith-Waterman score: 7209; 95.6% identity (95.6% similar) in 1126 aa overlap (1-1126:1-1076)
10 20 30 40 50 60
pF1KB4 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_016 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTL-GAGLGTNASLAQMVSGLVG
490 500 510 520 530
550 560 570 580 590 600
pF1KB4 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB4 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB4 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB4 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB4 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB4 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB4 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB4 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KB4 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
::::::::::::::::::::::::::
XP_016 QSQRKVKPQPPLSDAYLSGMPAKRRK----------------------------------
1020 1030 1040
1090 1100 1110 1120
pF1KB4 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
:::::::::::::::::::::::::::::::
XP_016 ---------------LRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
1050 1060 1070
>>XP_016866782 (OMIM: 142590) PREDICTED: large proline-r (1108 aa)
initn: 6608 init1: 6608 opt: 6619 Z-score: 2584.9 bits: 490.1 E(85289): 3.1e-137
Smith-Waterman score: 7479; 98.4% identity (98.4% similar) in 1126 aa overlap (1-1126:1-1108)
10 20 30 40 50 60
pF1KB4 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
:::::::::::::::::::::: ::::::::::::::::::::
XP_016 GASVHDRNANSYVMVGTFNLPS------------------EPRVRLVMAQHMIRDIQTLL
130 140 150 160
190 200 210 220 230 240
pF1KB4 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB4 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB4 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB4 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB4 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB4 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB4 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB4 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB4 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
650 660 670 680 690 700
730 740 750 760 770 780
pF1KB4 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
710 720 730 740 750 760
790 800 810 820 830 840
pF1KB4 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
770 780 790 800 810 820
850 860 870 880 890 900
pF1KB4 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
830 840 850 860 870 880
910 920 930 940 950 960
pF1KB4 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
890 900 910 920 930 940
970 980 990 1000 1010 1020
pF1KB4 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
950 960 970 980 990 1000
1030 1040 1050 1060 1070 1080
pF1KB4 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
1010 1020 1030 1040 1050 1060
1090 1100 1110 1120
pF1KB4 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
1070 1080 1090 1100
>>XP_016866787 (OMIM: 142590) PREDICTED: large proline-r (1028 aa)
initn: 3865 init1: 3618 opt: 6514 Z-score: 2544.7 bits: 482.6 E(85289): 5.3e-135
Smith-Waterman score: 6768; 91.3% identity (91.3% similar) in 1126 aa overlap (1-1126:1-1028)
10 20 30 40 50 60
pF1KB4 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVG
:::::::::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_016 TLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTL-GAGLGTNASLAQMVSGLVG
490 500 510 520 530
550 560 570 580 590 600
pF1KB4 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQ
540 550 560 570 580 590
610 620 630 640 650 660
pF1KB4 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPP
600 610 620 630 640 650
670 680 690 700 710 720
pF1KB4 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLGARAGSSESI
660 670 680 690 700 710
730 740 750 760 770 780
pF1KB4 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQPLQRLQPQLR
720 730 740 750 760 770
790 800 810 820 830 840
pF1KB4 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRTNLEFLQEQF
780 790 800 810 820 830
850 860 870 880 890 900
pF1KB4 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVINGRIRRMSRGV
840 850 860 870 880 890
910 920 930 940 950 960
pF1KB4 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEVQGAERASPE
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KB4 PQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPEWVPIIQQDI
:: ::::::::::
XP_016 PQ------------------------------------------------EWVPIIQQDI
960 970
1030 1040 1050 1060 1070 1080
pF1KB4 QSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGARPLTSPESLS
::::::::::::::::::::::::::
XP_016 QSQRKVKPQPPLSDAYLSGMPAKRRK----------------------------------
980 990
1090 1100 1110 1120
pF1KB4 RDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
:::::::::::::::::::::::::::::::
XP_016 ---------------LRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
1000 1010 1020
>>XP_016866778 (OMIM: 142590) PREDICTED: large proline-r (1135 aa)
initn: 7629 init1: 4574 opt: 4783 Z-score: 1873.9 bits: 358.6 E(85289): 1.2e-97
Smith-Waterman score: 7615; 99.2% identity (99.2% similar) in 1135 aa overlap (1-1126:1-1135)
10 20 30 40 50 60
pF1KB4 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEPNDSTSTAVEEPDSLEVLVKTLDSQTRTFIVGAQMNVKEFKEHIAASVSIPSEKQRLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YQGRVLQDDKKLQEYNVGGKVIHLVERAPPQTHLPSGASSGTGSASATHGGGSPPGTRGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GASVHDRNANSYVMVGTFNLPSDGSAVDVHINMEQAPIQSEPRVRLVMAQHMIRDIQTLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRMECRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPELTPGPAPAGPTPAPETNAPNHPSPAEYVEVLQELQRLESRLQPFLQRYYEVLGAAAT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TDYNNNHEGREEDQRLINLVGESLRLLGNTFVALSDLRCNLACTPPRHLHVVRPMSHYTT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PMVLQQAAIPIQINVGTTVTMTGNGTRPPPTPNAEAPPPGPGQASSVAPSSTNVESSAEG
370 380 390 400 410 420
430 440 450 460 470
pF1KB4 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQ---------DSGTQPGGVPSAPTG
:::::::::::::::::::::::::::::::::::: :::::::::::::::
XP_016 APPPGPAPPPATSHPRVIRISHQSVEPVVMMHMNIQGPLSLSPCPDSGTQPGGVPSAPTG
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB4 PLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQARPSHPGGPPVSGTLQGAGLGTNASL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB4 AQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPT
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB4 PQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQPSMADLQFSQLLGNLLGPAGPGAGGSGVASPTITVAMPGVPAFLQGMTDFLQATQTAP
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB4 PPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPPPPPPPPPPAPEQQTMPPPGSPSGGAGSPGGLGLESLSPEFFTSVVQGVLSSLLGSLG
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB4 ARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ARAGSSESIAAFIQRLSGSSNIFEPGADGALGFFGALLSLLCQNFSMVDVVMLLHGHFQP
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB4 LQRLQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LQRLQPQLRSFFHQHYLGGQEPTPSNIRMATHTLITGLEEYVRESFSLVQVQPGVDIIRT
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB4 NLEFLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVING
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLEFLQEQFNSIAAHVLHCTDSGFGARLLELCNQGLFECLALNLHCLGGQQMELAAVING
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB4 RIRRMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIRRMSRGVNPSLVSWLTTMMGLRLQVVLEHMPVGPDAILRYVRRVGDPPQPLPEEPMEV
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB4 QGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QGAERASPEPQRENASPAPGTTAEEAMSRGPPPAPEGGSRDEQDGASAETEPWAAAVPPE
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB4 WVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WVPIIQQDIQSQRKVKPQPPLSDAYLSGMPAKRRKTMQGEGPQLLLSEAVSRAAKAAGAR
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120
pF1KB4 PLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTSPESLSRDLEAPEVQESYRQQLRSDIQKRLQEDPNYSPQRFPNAQRAFADDP
1090 1100 1110 1120 1130
1126 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:15:58 2016 done: Thu Nov 3 15:16:01 2016
Total Scan time: 20.560 Total Display time: 0.500
Function used was FASTA [36.3.4 Apr, 2011]