Result of FASTA (omim) for
pF1KB4593
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4593, 780 aa
1>>>pF1KB4593 780 - 780 aa - 780 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.2617+/-0.000393; mu= -3.4979+/- 0.025
mean_var=212.2101+/-43.719, 0's: 0 Z-trim(120.2): 413 B-trim: 1221 in 1/55
Lambda= 0.088042
statistics sampled from 34629 (35060) to 34629 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.732), E-opt: 0.2 (0.411), width: 16
Scan time: 12.090
The best scores are: opt bits E(85289)
NP_002826 (OMIM: 600079) tyrosine-protein phosphat ( 780) 5304 686.8 9.3e-197
NP_001124480 (OMIM: 600079) tyrosine-protein phosp ( 661) 4515 586.6 1.2e-166
XP_016867963 (OMIM: 600079) PREDICTED: tyrosine-pr ( 665) 4457 579.2 2e-164
XP_005250575 (OMIM: 600079) PREDICTED: tyrosine-pr ( 665) 4457 579.2 2e-164
XP_006716136 (OMIM: 600079) PREDICTED: tyrosine-pr ( 748) 4458 579.3 2e-164
NP_001124481 (OMIM: 600079) tyrosine-protein phosp ( 650) 4442 577.3 7.2e-164
XP_011514746 (OMIM: 600079) PREDICTED: tyrosine-pr ( 567) 3703 483.4 1.1e-135
NP_001180360 (OMIM: 152700,180300,222100,600716) t ( 779) 1477 200.7 2e-50
XP_016856495 (OMIM: 152700,180300,222100,600716) P ( 311) 1354 184.9 4.4e-46
XP_011539525 (OMIM: 152700,180300,222100,600716) P ( 715) 1355 185.2 8.5e-46
XP_016856493 (OMIM: 152700,180300,222100,600716) P ( 771) 1355 185.2 9.1e-46
XP_011539524 (OMIM: 152700,180300,222100,600716) P ( 773) 1355 185.2 9.1e-46
NP_057051 (OMIM: 152700,180300,222100,600716) tyro ( 807) 1355 185.2 9.5e-46
XP_011539523 (OMIM: 152700,180300,222100,600716) P ( 781) 1318 180.5 2.4e-44
NP_036543 (OMIM: 152700,180300,222100,600716) tyro ( 752) 1170 161.7 1.1e-38
NP_055184 (OMIM: 606587) tyrosine-protein phosphat ( 460) 933 131.5 7.8e-30
XP_006712480 (OMIM: 606587) PREDICTED: tyrosine-pr ( 464) 933 131.5 7.9e-30
XP_016856494 (OMIM: 152700,180300,222100,600716) P ( 692) 867 123.2 3.8e-27
NP_536859 (OMIM: 176883) tyrosine-protein phosphat ( 624) 692 101.0 1.7e-20
XP_006719057 (OMIM: 176883) PREDICTED: tyrosine-pr ( 481) 665 97.5 1.4e-19
NP_002822 (OMIM: 176883) tyrosine-protein phosphat ( 595) 665 97.5 1.7e-19
XP_011519290 (OMIM: 176883) PREDICTED: tyrosine-pr ( 597) 665 97.5 1.7e-19
NP_536858 (OMIM: 176883) tyrosine-protein phosphat ( 597) 665 97.5 1.7e-19
XP_016883102 (OMIM: 608712) PREDICTED: receptor-ty (1436) 660 97.0 6e-19
NP_008981 (OMIM: 608712) receptor-type tyrosine-pr (1441) 660 97.0 6e-19
XP_016883101 (OMIM: 608712) PREDICTED: receptor-ty (1455) 660 97.0 6.1e-19
NP_573400 (OMIM: 608712) receptor-type tyrosine-pr (1460) 660 97.0 6.1e-19
XP_016866637 (OMIM: 602545) PREDICTED: receptor-ty (1368) 647 95.4 1.8e-18
NP_001278913 (OMIM: 602545) receptor-type tyrosine (1439) 647 95.4 1.9e-18
NP_002835 (OMIM: 602545) receptor-type tyrosine-pr (1440) 647 95.4 1.9e-18
XP_011534318 (OMIM: 602545) PREDICTED: receptor-ty (1456) 647 95.4 1.9e-18
XP_011539527 (OMIM: 152700,180300,222100,600716) P ( 749) 639 94.3 2.1e-18
NP_001295226 (OMIM: 152700,180300,222100,600716) t ( 783) 639 94.3 2.2e-18
NP_109595 (OMIM: 600579,614196) receptor-type tyro ( 377) 631 93.1 2.3e-18
NP_109593 (OMIM: 600579,614196) receptor-type tyro ( 377) 631 93.1 2.3e-18
NP_109596 (OMIM: 600579,614196) receptor-type tyro ( 405) 631 93.2 2.4e-18
NP_109594 (OMIM: 600579,614196) receptor-type tyro ( 405) 631 93.2 2.4e-18
XP_016873574 (OMIM: 600925) PREDICTED: receptor-ty (1321) 642 94.7 2.7e-18
NP_002834 (OMIM: 600925) receptor-type tyrosine-pr (1337) 642 94.7 2.7e-18
XP_016873573 (OMIM: 600925) PREDICTED: receptor-ty (1344) 642 94.7 2.7e-18
XP_016873572 (OMIM: 600925) PREDICTED: receptor-ty (1363) 642 94.7 2.8e-18
XP_016882551 (OMIM: 602510) PREDICTED: receptor-ty ( 928) 637 94.0 3.1e-18
XP_016882552 (OMIM: 602510) PREDICTED: receptor-ty ( 928) 637 94.0 3.1e-18
XP_011525490 (OMIM: 602510) PREDICTED: receptor-ty ( 928) 637 94.0 3.1e-18
NP_001154912 (OMIM: 602510) receptor-type tyrosine ( 937) 637 94.0 3.1e-18
XP_016882550 (OMIM: 602510) PREDICTED: receptor-ty ( 959) 637 94.0 3.1e-18
NP_002833 (OMIM: 602510) receptor-type tyrosine-pr (1115) 637 94.1 3.6e-18
XP_016882549 (OMIM: 602510) PREDICTED: receptor-ty (1121) 637 94.1 3.6e-18
XP_011525485 (OMIM: 602510) PREDICTED: receptor-ty (1122) 637 94.1 3.6e-18
XP_016882547 (OMIM: 602510) PREDICTED: receptor-ty (1130) 637 94.1 3.6e-18
>>NP_002826 (OMIM: 600079) tyrosine-protein phosphatase (780 aa)
initn: 5304 init1: 5304 opt: 5304 Z-score: 3653.4 bits: 686.8 E(85289): 9.3e-197
Smith-Waterman score: 5304; 100.0% identity (100.0% similar) in 780 aa overlap (1-780:1-780)
10 20 30 40 50 60
pF1KB4 MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 YEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 YEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPH
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 PVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 STIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 STIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 LSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 PENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNP
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 LHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTH
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 SGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 NEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
730 740 750 760 770 780
>>NP_001124480 (OMIM: 600079) tyrosine-protein phosphata (661 aa)
initn: 4515 init1: 4515 opt: 4515 Z-score: 3113.0 bits: 586.6 E(85289): 1.2e-166
Smith-Waterman score: 4515; 100.0% identity (100.0% similar) in 661 aa overlap (120-780:1-661)
90 100 110 120 130 140
pF1KB4 NANFIKGVYGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPL
::::::::::::::::::::::::::::::
NP_001 MIWEYNVVIIVMACREFEMGRKKCERYWPL
10 20 30
150 160 170 180 190 200
pF1KB4 YGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGEDPITFAPFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSI
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB4 LDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEM
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB4 RTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIEPEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIEPEK
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB4 QDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHP
220 230 240 250 260 270
390 400 410 420 430 440
pF1KB4 KPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKS
280 290 300 310 320 330
450 460 470 480 490 500
pF1KB4 FDGNTLLNRGHAIKIKSASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FDGNTLLNRGHAIKIKSASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVT
340 350 360 370 380 390
510 520 530 540 550 560
pF1KB4 PPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLT
400 410 420 430 440 450
570 580 590 600 610 620
pF1KB4 PSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASA
460 470 480 490 500 510
630 640 650 660 670 680
pF1KB4 TVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLAS
520 530 540 550 560 570
690 700 710 720 730 740
pF1KB4 EHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQ
580 590 600 610 620 630
750 760 770 780
pF1KB4 ISENPTEATDIGFGNRCGKPKGPRDPPSEWT
:::::::::::::::::::::::::::::::
NP_001 ISENPTEATDIGFGNRCGKPKGPRDPPSEWT
640 650 660
>>XP_016867963 (OMIM: 600079) PREDICTED: tyrosine-protei (665 aa)
initn: 4457 init1: 4457 opt: 4457 Z-score: 3073.1 bits: 579.2 E(85289): 2e-164
Smith-Waterman score: 4457; 100.0% identity (100.0% similar) in 653 aa overlap (128-780:13-665)
100 110 120 130 140 150
pF1KB4 YGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITF
::::::::::::::::::::::::::::::
XP_016 MLKRTDTRTYCHIIVMACREFEMGRKKCERYWPLYGEDPITF
10 20 30 40
160 170 180 190 200 210
pF1KB4 APFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 APFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMR
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB4 KYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAV
110 120 130 140 150 160
280 290 300 310 320 330
pF1KB4 QTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKP
170 180 190 200 210 220
340 350 360 370 380 390
pF1KB4 PRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVS
230 240 250 260 270 280
400 410 420 430 440 450
pF1KB4 SEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLN
290 300 310 320 330 340
460 470 480 490 500 510
pF1KB4 RGHAIKIKSASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RGHAIKIKSASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNS
350 360 370 380 390 400
520 530 540 550 560 570
pF1KB4 DTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVE
410 420 430 440 450 460
580 590 600 610 620 630
pF1KB4 TPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATST
470 480 490 500 510 520
640 650 660 670 680 690
pF1KB4 ESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRS
530 540 550 560 570 580
700 710 720 730 740 750
pF1KB4 EWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEA
590 600 610 620 630 640
760 770 780
pF1KB4 TDIGFGNRCGKPKGPRDPPSEWT
:::::::::::::::::::::::
XP_016 TDIGFGNRCGKPKGPRDPPSEWT
650 660
>>XP_005250575 (OMIM: 600079) PREDICTED: tyrosine-protei (665 aa)
initn: 4457 init1: 4457 opt: 4457 Z-score: 3073.1 bits: 579.2 E(85289): 2e-164
Smith-Waterman score: 4457; 100.0% identity (100.0% similar) in 653 aa overlap (128-780:13-665)
100 110 120 130 140 150
pF1KB4 YGPKAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITF
::::::::::::::::::::::::::::::
XP_005 MLKRTDTRTYCHIIVMACREFEMGRKKCERYWPLYGEDPITF
10 20 30 40
160 170 180 190 200 210
pF1KB4 APFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 APFKISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMR
50 60 70 80 90 100
220 230 240 250 260 270
pF1KB4 KYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAV
110 120 130 140 150 160
280 290 300 310 320 330
pF1KB4 QTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKP
170 180 190 200 210 220
340 350 360 370 380 390
pF1KB4 PRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVS
230 240 250 260 270 280
400 410 420 430 440 450
pF1KB4 SEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLN
290 300 310 320 330 340
460 470 480 490 500 510
pF1KB4 RGHAIKIKSASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RGHAIKIKSASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNS
350 360 370 380 390 400
520 530 540 550 560 570
pF1KB4 DTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVE
410 420 430 440 450 460
580 590 600 610 620 630
pF1KB4 TPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATST
470 480 490 500 510 520
640 650 660 670 680 690
pF1KB4 ESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRS
530 540 550 560 570 580
700 710 720 730 740 750
pF1KB4 EWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEA
590 600 610 620 630 640
760 770 780
pF1KB4 TDIGFGNRCGKPKGPRDPPSEWT
:::::::::::::::::::::::
XP_005 TDIGFGNRCGKPKGPRDPPSEWT
650 660
>>XP_006716136 (OMIM: 600079) PREDICTED: tyrosine-protei (748 aa)
initn: 4458 init1: 4458 opt: 4458 Z-score: 3073.0 bits: 579.3 E(85289): 2e-164
Smith-Waterman score: 5004; 95.9% identity (95.9% similar) in 780 aa overlap (1-780:1-748)
10 20 30 40 50 60
pF1KB4 MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM
:::::::::::::::::::::::::::::::::::
XP_006 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIK-------------------------
70 80 90
130 140 150 160 170 180
pF1KB4 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 -------IIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL
100 110 120 130 140
190 200 210 220 230 240
pF1KB4 EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB4 ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL
210 220 230 240 250 260
310 320 330 340 350 360
pF1KB4 YEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPH
270 280 290 300 310 320
370 380 390 400 410 420
pF1KB4 PVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNE
330 340 350 360 370 380
430 440 450 460 470 480
pF1KB4 STIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQE
390 400 410 420 430 440
490 500 510 520 530 540
pF1KB4 LSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHG
450 460 470 480 490 500
550 560 570 580 590 600
pF1KB4 PENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNP
510 520 530 540 550 560
610 620 630 640 650 660
pF1KB4 LHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESISTRKVLPMSIARHNIAGTTH
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB4 SGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSE
630 640 650 660 670 680
730 740 750 760 770 780
pF1KB4 NEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
690 700 710 720 730 740
>>NP_001124481 (OMIM: 600079) tyrosine-protein phosphata (650 aa)
initn: 4442 init1: 4442 opt: 4442 Z-score: 3063.0 bits: 577.3 E(85289): 7.2e-164
Smith-Waterman score: 4442; 100.0% identity (100.0% similar) in 650 aa overlap (131-780:1-650)
110 120 130 140 150 160
pF1KB4 KAYVATQGPLANTVIDFWRMIWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPF
::::::::::::::::::::::::::::::
NP_001 MACREFEMGRKKCERYWPLYGEDPITFAPF
10 20 30
170 180 190 200 210 220
pF1KB4 KISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KISCEDEQARTDYFIRTLLLEFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQ
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB4 EHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTK
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB4 EQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRT
160 170 180 190 200 210
350 360 370 380 390 400
pF1KB4 RSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQ
220 230 240 250 260 270
410 420 430 440 450 460
pF1KB4 HSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGH
280 290 300 310 320 330
470 480 490 500 510 520
pF1KB4 AIKIKSASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIKIKSASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTP
340 350 360 370 380 390
530 540 550 560 570 580
pF1KB4 PRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPD
400 410 420 430 440 450
590 600 610 620 630 640
pF1KB4 LVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATSTESI
460 470 480 490 500 510
650 660 670 680 690 700
pF1KB4 STRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWS
520 530 540 550 560 570
710 720 730 740 750 760
pF1KB4 ELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDI
580 590 600 610 620 630
770 780
pF1KB4 GFGNRCGKPKGPRDPPSEWT
::::::::::::::::::::
NP_001 GFGNRCGKPKGPRDPPSEWT
640 650
>>XP_011514746 (OMIM: 600079) PREDICTED: tyrosine-protei (567 aa)
initn: 3703 init1: 3703 opt: 3703 Z-score: 2556.6 bits: 483.4 E(85289): 1.1e-135
Smith-Waterman score: 3703; 100.0% identity (100.0% similar) in 548 aa overlap (233-780:20-567)
210 220 230 240 250 260
pF1KB4 PSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGAICAIDYTWNLLKAGKIPEEFNV
::::::::::::::::::::::::::::::
XP_011 MNKQEQTTSSGHSYLNFKIAGCGRTGAICAIDYTWNLLKAGKIPEEFNV
10 20 30 40
270 280 290 300 310 320
pF1KB4 FNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQLYEIHGAQKIADGVNEINTENMV
50 60 70 80 90 100
330 340 350 360 370 380
pF1KB4 SSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPHPVPPILTPSPPSAFPTVTTVWQ
110 120 130 140 150 160
390 400 410 420 430 440
pF1KB4 DNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DNDRYHPKPVLHMVSSEQHSADLNRNYSKSTELPGKNESTIEQIDKKLERNLSFEIKKVP
170 180 190 200 210 220
450 460 470 480 490 500
pF1KB4 LQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LQEGPKSFDGNTLLNRGHAIKIKSASPCIADKISKPQELSSDLNVGDTSQNSCVDCSVTQ
230 240 250 260 270 280
510 520 530 540 550 560
pF1KB4 SNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVTWSFHGPENAIPIPDLSEGNSSDINYQT
290 300 310 320 330 340
570 580 590 600 610 620
pF1KB4 RKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKTVSLTPSPTTQVETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKT
350 360 370 380 390 400
630 640 650 660 670 680
pF1KB4 NISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NISTASATVSAATSTESISTRKVLPMSIARHNIAGTTHSGAEKDVDVSEDSPPPLPERTP
410 420 430 440 450 460
690 700 710 720 730 740
pF1KB4 ESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ESFVLASEHNTPVRSEWSELQSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPT
470 480 490 500 510 520
750 760 770 780
pF1KB4 FSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
::::::::::::::::::::::::::::::::::::::
XP_011 FSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
530 540 550 560
>>NP_001180360 (OMIM: 152700,180300,222100,600716) tyros (779 aa)
initn: 1634 init1: 1318 opt: 1477 Z-score: 1026.3 bits: 200.7 E(85289): 2e-50
Smith-Waterman score: 1520; 37.1% identity (63.1% similar) in 819 aa overlap (1-779:1-777)
10 20 30 40 50 60
pF1KB4 MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK
:.: :::.::....:. : ...:: .:..:.: ::::...: :::...:: .:.:
NP_001 MDQREILQKFLDEAQSKKIT----KEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIK
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM
:::::::::.:.:::.:.: : ..::.::::::::::::::::.::::::..:..:::::
NP_001 KNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL
::::.:.:::::: :.:::.::::::: :: . :.::..::: :. ..::.:::: .
NP_001 IWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA
.:..:.: .::::: ::::::::::.: ::..: .: ::: ..:::::::::::::::.
NP_001 KFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL
:::::::: ::: : :::.:.::.::.:::::: : :::.::::::. :. .::..:...
NP_001 ICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDV
240 250 260 270 280 290
310 320 330 340 350
pF1KB4 YEIHGAQKIADGVNEINTENMVSSIEPEKQ-----DSPPPKPPRTRSCLVEGDAKEEILQ
: : .. .::.... :::. :: :. :.. . : . . :
NP_001 --------IRD--KHSGTESQAKHCIPEKNHTLQADSYSPNLPKSTT-----KAAKMMNQ
300 310 320 330 340
360 370 380 390 400 410
pF1KB4 PPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTEL
. : : : ... :: :. .:: ...:...
NP_001 QRTKMEIKE----SSSFDFRTSEISAKEELVLHPAK----SSTSFDFLELNYSFDKNADT
350 360 370 380 390
420 430 440 450 460
pF1KB4 PGKNES-TIEQIDKKLERNLSFEIKKVPLQEG-----PKSFDGNTLLNRGHAIKIKSASP
: .. .. . . :... :... .. : :: : . : . .. . :: .:
NP_001 TMKWQTKAFPIVGEPLQKHQSLDLGSL-LFEGCSNSKPVNAAGRYFNSKVPITRTKS-TP
400 410 420 430 440 450
470 480 490 500 510 520
pF1KB4 CIADKISKPQELSSDLNVG---DTSQNSC-VDCSVTQSNKVSVTPPEESQNSDTPPRPDR
. . .:..: : . . ..:: :. .. . .:: . . : :. . :
NP_001 FELIQQRETKEVDSKENFSYLESQPHDSCFVEMQAQKVMHVSSAELNYSLPYDSKHQI-R
460 470 480 490 500 510
530 540 550 560 570
pF1KB4 LPLDEKGHVTWSFHGPENAIPI---PDLSE----GNSS--DINYQTRKTVSLTPSPTTQV
. : : . : : . ::. : .: :.:: ... .. .. :: .
NP_001 NASNVKHHDS-SALGVYSYIPLVENPYFSSWPPSGTSSKMSLDLPEKQDGTVFPSSLLPT
520 530 540 550 560
580 590 600 610 620 630
pF1KB4 ETPDLVDHDNTSPLFRTPLSFTNPLHSDDSDSDERNSDGAVTQNKTNISTASATVSAATS
. .: .. :. . ::...: . :. :...:: . :. . .
NP_001 SSTSLFSYYNS----HDSLSLNSPTNI----SSLLNQESAVLATAPRIDDEIPPPLPVRT
570 580 590 600 610 620
640 650 660 670 680
pF1KB4 TES-ISTRKV------LPMSIARHNIAGTTHSGAEKDVDVSEDSPPP-LPERTPESFVLA
:: : .... .: :.. . .. . .... ...:::: ::::: ::: ::
NP_001 PESFIVVEEAGEFSPNVPKSLSS-AVKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLA
630 640 650 660 670 680
690 700 710 720 730 740
pF1KB4 SEHNTPVRS--EWSE-----LQSQERSEQK-KSEGLITSENEKCDHPAGGIHYEMCIECP
.: ..: .: .... :.: :. : ... : . ... .: ::
NP_001 DEDCMQAQSIETYSTSYPDTMENSTSSKQTLKTPGKSFTRS-KSLKILRNMKKSICNSCP
690 700 710 720 730
750 760 770 780
pF1KB4 PTFSDKREQISENPTEATDIGFGNRCGKPKGPRDPPSEWT
:. . : :.: . ..::.:: .::::::.:: :
NP_001 PNKPAESVQ-SNNSSSFLNFGFANRFSKPKGPRNPPPTWNI
740 750 760 770
>>XP_016856495 (OMIM: 152700,180300,222100,600716) PREDI (311 aa)
initn: 1346 init1: 1315 opt: 1354 Z-score: 948.4 bits: 184.9 E(85289): 4.4e-46
Smith-Waterman score: 1354; 63.3% identity (87.3% similar) in 300 aa overlap (1-300:1-296)
10 20 30 40 50 60
pF1KB4 MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK
:.: :::.::....:. : ...:: .:..:.: ::::...: :::...:: .:.:
XP_016 MDQREILQKFLDEAQSKKIT----KEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIK
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM
:::::::::.:.:::.:.: : ..::.::::::::::::::::.::::::..:..:::::
XP_016 KNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL
::::.:.:::::: :.:::.::::::: :: . :.::..::: :. ..::.:::: .
XP_016 IWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA
.:..:.: .::::: ::::::::::.: ::..: .: ::: ..:::::::::::::::.
XP_016 KFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL
:::::::: ::: : :::.:.::.::.:::::: : :::.::::::. :. .::..:...
XP_016 ICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDV
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 YEIHGAQKIADGVNEINTENMVSSIEPEKQDSPPPKPPRTRSCLVEGDAKEEILQPPEPH
XP_016 IRDKHSGTEPLTYFF
300 310
>>XP_011539525 (OMIM: 152700,180300,222100,600716) PREDI (715 aa)
initn: 1392 init1: 1318 opt: 1355 Z-score: 943.2 bits: 185.2 E(85289): 8.5e-46
Smith-Waterman score: 1430; 40.0% identity (64.1% similar) in 708 aa overlap (1-690:1-630)
10 20 30 40 50 60
pF1KB4 MEQVEILRKFIQRVQAMKSPDHNGEDNFARDFMRLRRLSTKYRTEKIYPTATGEKEENVK
:.: :::.::....:. : ...:: .:..:.: ::::...: :::...:: .:.:
XP_011 MDQREILQKFLDEAQSKKIT----KEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIK
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 KNRYKDILPFDHSRVKLTLKTPSQDSDYINANFIKGVYGPKAYVATQGPLANTVIDFWRM
:::::::::.:.:::.:.: : ..::.::::::::::::::::.::::::..:..:::::
XP_011 KNRYKDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 IWEYNVVIIVMACREFEMGRKKCERYWPLYGEDPITFAPFKISCEDEQARTDYFIRTLLL
::::.:.:::::: :.:::.::::::: :: . :.::..::: :. ..::.:::: .
XP_011 IWEYSVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 EFQNESRRLYQFHYVNWPDHDVPSSFDSILDMISLMRKYQEHEDVPICIHCSAGCGRTGA
.:..:.: .::::: ::::::::::.: ::..: .: ::: ..:::::::::::::::.
XP_011 KFNSETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 ICAIDYTWNLLKAGKIPEEFNVFNLIQEMRTQRHSAVQTKEQYELVHRAIAQLFEKQLQL
:::::::: ::: : :::.:.::.::.:::::: : :::.::::::. :. .::..:...
XP_011 ICAIDYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDV
240 250 260 270 280 290
310 320 330 340 350
pF1KB4 YEIHGAQKIADGVNEINTENMVSSIEPEKQ-----DSPPPKPPRTRSCLVEGDAKEEILQ
: : .. .::.... :::. :: :. :.. . : . . :
XP_011 --------IRD--KHSGTESQAKHCIPEKNHTLQADSYSPNLPKSTT-----KAAKMMNQ
300 310 320 330 340
360 370 380 390 400 410
pF1KB4 PPEPHPVPPILTPSPPSAFPTVTTVWQDNDRYHPKPVLHMVSSEQHSADLNRNYSKSTEL
. . :.: :. . ... ::: ..: :. ::: .
XP_011 QRTKMEI------KESSSFDFRTSEISAKEEL----VLHPAKSSTSFDFLELNYSFD---
350 360 370 380
420 430 440 450 460 470
pF1KB4 PGKNESTIEQIDKKLERNLSFEIKKVPLQEGPKSFDGNTLLNRGHAIKIKSASPCIADKI
:: .: . . : .: : :::. .:.: ..:: .: : .
XP_011 --KNADTTMKWQTK-----AFPIVGEPLQKH-QSLDLGSLLFEG----------C---SN
390 400 410 420
480 490 500 510 520 530
pF1KB4 SKPQELSSDLNVGDTSQNSCVDCSVTQSNKVSVTPPEESQNSDTPPRPDRLPLDEKGHVT
::: .:.. :: : . :.:. . .:... :. . . :. . :
XP_011 SKP------VNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDS--KENFSYLESQPHD-
430 440 450 460 470
540 550 560 570 580
pF1KB4 WSFHGPENAIPIPDLSEGNSSDINYQTRKTVSLTPSPTTQVETPDLVDHDNTS-------
: .: . .: :...:: :: . :... . : : ..:
XP_011 -SCFVEMQAQKVMHVS---SAELNY------SLPYDSKHQIRNASNVKHHDSSALGVYSY
480 490 500 510 520
590 600 610 620 630 640
pF1KB4 -PLFRTPLSFTNPLHSDDS----DSDERNSDGAVTQNKTNISTASATVSAATSTESISTR
:: ..: . : . .: : :.. ::.: .. ..... : .: .:.:
XP_011 IPLVENPYFSSWPPSGTSSKMSLDLPEKQ-DGTVFPSSLLPTSSTSLFSYYNSHDSLSLN
530 540 550 560 570 580
650 660 670 680 690 700
pF1KB4 KVLPMSIARH-NIAGTTHSGAEKDVDVSEDSPPPLPERTPESFVLASEHNTPVRSEWSEL
. : .:. : ... . : . .... ::::: :::::... :
XP_011 S--PTNISSLLNQESAVLATAPR---IDDEIPPPLPVWTPESFIVVEEAGEFSPNVPKSL
590 600 610 620 630 640
710 720 730 740 750 760
pF1KB4 QSQERSEQKKSEGLITSENEKCDHPAGGIHYEMCIECPPTFSDKREQISENPTEATDIGF
XP_011 SSAVKVKIGTSLEWGGTSEPKKFDDSVILRPSKSVKLRSPKSDREKKGGNSSSRDQPTND
650 660 670 680 690 700
780 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:12:33 2016 done: Thu Nov 3 15:12:35 2016
Total Scan time: 12.090 Total Display time: 0.200
Function used was FASTA [36.3.4 Apr, 2011]